Genome ID：GCA_046531615.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	24	31	39.26

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
MKPKCPNB_1	1354362	1355099	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1
MKPKCPNB_1	1351518	1353437	tet(M)	ARO:3000186	tet(M)	99.06	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
MKPKCPNB_1	1354362	1355099	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
MKPKCPNB_1	1351518	1353437	tet(M)	Doxycycline, Tetracycline, Minocycline	99.53	100.00	X75073

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
MKPKCPNB_1	1354362	1355096	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
MKPKCPNB_1	1351518	1353434	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	99.84	100.00	WP_000691736.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
MKPKCPNB_1	952817	953557	STER_RS05305	0.0	Capsule	Immune modulation	95.28	100.00	WP_011681174
MKPKCPNB_1	1618305	1619156	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
MKPKCPNB_1	952817	953557	STU_RS14635	0.0	Capsule	Immune modulation	94.60	100.00	WP_011226046
MKPKCPNB_1	953615	954982	STU_RS14630	0.0	Capsule	Immune modulation	94.30	100.00	WP_011226045
MKPKCPNB_1	952817	953552	STR_RS05250	0.0	Capsule	Immune modulation	94.02	98.13	WP_011227246
MKPKCPNB_1	953615	954980	STER_RS05300	0.0	Capsule	Immune modulation	94.00	99.85	WP_011681173
MKPKCPNB_1	1615933	1617204	STU_RS16265	0.0	Capsule	Immune modulation	93.95	99.76	WP_011226331
MKPKCPNB_1	949914	951374	STER_RS05320	0.0	Capsule	Immune modulation	93.91	100.00	WP_011681177
MKPKCPNB_1	949914	951374	STU_RS14650	0.0	Capsule	Immune modulation	93.70	100.14	WP_011226049
MKPKCPNB_1	949914	951374	STR_RS05265	0.0	Capsule	Immune modulation	93.09	100.14	WP_041827043
MKPKCPNB_1	1610364	1611173	STU_RS16245	0.0	Capsule	Immune modulation	92.96	100.00	WP_002948020
MKPKCPNB_1	1606324	1608108	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
MKPKCPNB_1	1614972	1615930	STU_RS16260	0.0	Capsule	Immune modulation	92.81	94.86	WP_011226330
MKPKCPNB_1	1611157	1612113	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
MKPKCPNB_1	1609159	1610364	STU_RS16240	0.0	Capsule	Immune modulation	92.45	100.00	WP_011226326
MKPKCPNB_1	951375	952106	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
MKPKCPNB_1	1612110	1613258	STU_RS16255	0.0	Capsule	Immune modulation	91.66	99.83	WP_041828290
MKPKCPNB_1	951375	952106	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
MKPKCPNB_1	775049	775918	rfbA	0.0	Capsule	Immune modulation	91.38	100.00	WP_011681286
MKPKCPNB_1	951375	952106	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
MKPKCPNB_1	37025	37864	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
MKPKCPNB_1	775918	776511	STR_RS05880	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
MKPKCPNB_1	1608105	1609139	STU_RS16235	0.0	Capsule	Immune modulation	90.91	99.15	WP_002948022
MKPKCPNB_1	775918	776511	STER_RS06030	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
MKPKCPNB_1	775918	776511	STU_RS15260	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
MKPKCPNB_1	1072786	1074444	fbp54	0.0	FBPs	Adherence	90.42	99.94	WP_011227179
MKPKCPNB_1	952115	952807	STR_RS05255	0.0	Capsule	Immune modulation	88.49	99.71	WP_011227247
MKPKCPNB_1	952115	952807	STU_RS14640	0.0	Capsule	Immune modulation	88.49	99.71	WP_011226047
MKPKCPNB_1	604999	606302	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
MKPKCPNB_1	952115	952807	STER_RS05310	0.0	Capsule	Immune modulation	87.48	99.71	WP_011681175
MKPKCPNB_1	1933117	1934127	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
MKPKCPNB_1	1223676	1224437	srtA	0.0	Sortase A	Exoenzyme	84.16	99.74	-
MKPKCPNB_1	776776	777822	rfbB	0.0	Capsule	Immune modulation	81.12	99.90	WP_009659423
MKPKCPNB_1	134108	135391	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
MKPKCPNB_1	965095	965678	SPD_RS01775	1.29e-146	Capsule	Immune modulation	83.08	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
MKPKCPNB_1	1227125	1228099	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	95.69	99.09	AAK75326
MKPKCPNB_1	1215541	1214468	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
MKPKCPNB_1	1809902	1812208	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
MKPKCPNB_1	1394514	1395995	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
MKPKCPNB_1	515709	516677	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
MKPKCPNB_1	1187002	1184756	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
MKPKCPNB_1	22603	23574	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
MKPKCPNB_1	1280080	1273517	PrtA	0.0	serine protease	90.05	101.96	ABJ55268
MKPKCPNB_1	749673	751403	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
MKPKCPNB_1	1661222	1660071	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
MKPKCPNB_1	1632566	1630578	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
MKPKCPNB_1	2165028	2163550	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
MKPKCPNB_1	604999	606300	Eno	0.0	enolase	86.44	99.77	ABP90468
MKPKCPNB_1	2149681	2147789	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
MKPKCPNB_1	1181838	1183547	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
MKPKCPNB_1	58891	59982	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
MKPKCPNB_1	1987966	1988976	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
MKPKCPNB_1	1046973	1048334	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
MKPKCPNB_1	590593	591483	bglB	2.71e-177	putative phospho--glucosidase	87.88	99.66	AAK33487
MKPKCPNB_1	1140955	1141893	SP_0676	1.87e-168	transcription facot	81.79	97.20	AAK74821
MKPKCPNB_1	1184570	1183713	metF	5.87e-167	methionine biosynthesis enzymes	86.71	99.31	AAK74739
MKPKCPNB_1	1090193	1089408	pnuC	9.15e-149	NAD salvage pathway importer	87.02	97.40	AAK75931
MKPKCPNB_1	904824	905528	covR	3.45e-125	responder protein	85.11	100.00	AAK71319
MKPKCPNB_1	1304717	1304046	rr01	1.57e-124	response regulator	83.93	99.56	CAB54566
MKPKCPNB_1	1177870	1177199	ciaR	2.09e-124	two component system response regulator	86.16	99.12	AIK75708
MKPKCPNB_1	1177870	1177202	CiaR	3.86e-124	two-component response regulator	87.44	99.55	AAK74935
MKPKCPNB_1	278548	279234	CovR	4.77e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
MKPKCPNB_1	904824	905528	walR	6.33e-119	DNA-binding response regulator	81.70	100.00	ANC99504
MKPKCPNB_1	60155	60550	SpxA2	2.15e-74	transcriptional regulator	91.67	100.00	ERL21461
MKPKCPNB_1	1035484	1035083	SpxA1	2.41e-68	transcriptional regulator	82.09	100.00	ERL19273
MKPKCPNB_1	120841	121254	GrpE	4.01e-66	protein grpE	81.16	80.59	ABP89267
MKPKCPNB_1	135558	136049	RopE (M5005_Spy_1611)	1.05e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
MKPKCPNB_1	1809902	1812202	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
MKPKCPNB_1	2024370	2023351	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451