Genome ID：GCA_047460085.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	17	34	38.07

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
HCKODEND_6	126170	127387	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
HCKODEND_6	124587	126050	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
HCKODEND_6	126173	127387	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
HCKODEND_6	124590	126050	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HCKODEND_7	51148	51864	STER_RS07085	0.0	Capsule	Immune modulation	96.79	100.00	WP_011681442
HCKODEND_1	223799	225259	STER_RS05320	0.0	Capsule	Immune modulation	96.58	100.00	WP_011681177
HCKODEND_1	223799	225259	STU_RS14650	0.0	Capsule	Immune modulation	96.23	100.21	WP_011226049
HCKODEND_1	223799	225259	STR_RS05265	0.0	Capsule	Immune modulation	95.69	100.21	WP_041827043
HCKODEND_1	220194	221559	STER_RS05300	0.0	Capsule	Immune modulation	95.17	99.85	WP_011681173
HCKODEND_1	220192	221559	STU_RS14630	0.0	Capsule	Immune modulation	94.37	100.00	WP_011226045
HCKODEND_1	221616	222356	STER_RS05305	0.0	Capsule	Immune modulation	94.06	100.00	WP_011681174
HCKODEND_7	46152	47003	rfbD	0.0	Capsule	Immune modulation	93.90	100.00	WP_014621820
HCKODEND_1	223067	223798	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
HCKODEND_1	223067	223798	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
HCKODEND_1	221616	222356	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
HCKODEND_1	223067	223798	STR_RS05260	0.0	Capsule	Immune modulation	93.03	100.00	WP_011227248
HCKODEND_7	52210	52980	STER_RS07075	0.0	Capsule	Immune modulation	92.88	99.10	WP_011681440
HCKODEND_1	221621	222356	STR_RS05250	0.0	Capsule	Immune modulation	92.80	98.13	WP_011227246
HCKODEND_13	24504	25097	STR_RS05880	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
HCKODEND_13	24504	25097	STER_RS06030	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
HCKODEND_13	24504	25097	STU_RS15260	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
HCKODEND_13	23635	24504	rfbA	0.0	Capsule	Immune modulation	90.69	100.00	WP_011681286
HCKODEND_1	114795	116453	fbp54	0.0	FBPs	Adherence	90.48	99.94	WP_011227179
HCKODEND_15	19244	20083	cbpD	0.0	Autolysin	Exoenzyme	89.76	100.00	WP_011226733
HCKODEND_1	222366	223058	STR_RS05255	0.0	Capsule	Immune modulation	88.62	99.86	WP_011227247
HCKODEND_1	222366	223058	STU_RS14640	0.0	Capsule	Immune modulation	88.62	99.86	WP_011226047
HCKODEND_2	14433	15443	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.55	99.80	WP_002986042
HCKODEND_4	208455	209758	eno	0.0	Streptococcal enolase	Exoenzyme	88.32	99.54	WP_000022832
HCKODEND_1	222366	223058	STER_RS05310	0.0	Capsule	Immune modulation	87.75	99.86	WP_011681175
HCKODEND_13	25483	26529	rfbB	0.0	Capsule	Immune modulation	84.45	99.90	WP_002263087
HCKODEND_3	27128	27889	srtA	0.0	Sortase A	Exoenzyme	83.75	99.87	-
HCKODEND_5	1891	3174	tig/ropA	0.0	Trigger factor	Stress survival	81.08	99.53	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HCKODEND_3	30579	31553	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.61	99.09	AAK75326
HCKODEND_3	18994	17921	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
HCKODEND_2	135843	133537	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.28	99.22	AAK74619
HCKODEND_1	324	2570	metE	0.0	methionine biosynthesis enzymes	93.32	100.00	AAK74738
HCKODEND_3	186920	188401	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
HCKODEND_4	118014	118982	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
HCKODEND_15	4820	5791	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HCKODEND_3	80297	73734	PrtA	0.0	serine protease	90.10	101.96	ABJ55268
HCKODEND_6	1892	162	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HCKODEND_7	3815	4966	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HCKODEND_7	32422	34410	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
HCKODEND_11	49416	47938	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
HCKODEND_4	208455	209756	Eno	0.0	enolase	86.44	99.77	ABP90468
HCKODEND_11	34088	32196	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
HCKODEND_1	5492	3783	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
HCKODEND_16	2725	1634	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HCKODEND_8	86856	85846	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HCKODEND_1	130384	129023	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
HCKODEND_4	194049	194939	bglB	2.66e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
HCKODEND_1	47799	46849	SP_0676	4.94e-169	transcription facot	81.07	98.45	AAK74821
HCKODEND_1	2760	3617	metF	1.54e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
HCKODEND_3	112370	111699	rr01	1.04e-126	response regulator	84.38	99.56	CAB54566
HCKODEND_1	271027	270323	covR	5.64e-126	responder protein	85.11	100.00	AAK71319
HCKODEND_1	9460	10131	ciaR	3.41e-125	two component system response regulator	86.16	99.12	AIK75708
HCKODEND_1	9460	10128	CiaR	6.31e-125	two-component response regulator	87.44	99.55	AAK74935
HCKODEND_5	149710	150396	CovR	3.54e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
HCKODEND_1	271027	270323	walR	1.04e-119	DNA-binding response regulator	81.70	100.00	ANC99504
HCKODEND_16	694	299	SpxA2	1.50e-76	transcriptional regulator	91.67	100.00	ERL21461
HCKODEND_1	141850	142251	SpxA1	4.19e-68	transcriptional regulator	81.34	100.00	ERL19273
HCKODEND_10	83481	83894	GrpE	1.65e-67	protein grpE	81.16	80.59	ABP89267
HCKODEND_14	11312	11599	spr0479	1.25e-48	essential gene	85.42	98.97	AAK99283
HCKODEND_4	71393	71647	spr1327	9.56e-45	essential gene	92.94	100.00	AAL00131
HCKODEND_11	2861	3124	spr0175	3.89e-43	pathogenitcity related	85.23	100.00	AAK98979
HCKODEND_11	3687	3953	spr0177	5.42e-42	essential gene	83.15	88.12	AAK98981
HCKODEND_5	3341	3832	RopE (M5005_Spy_1611)	7.84e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HCKODEND_2	135843	133543	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
HCKODEND_8	50166	51185	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451