Genome ID：GCA_047460285.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	19	33	38.13

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
PGOPPEHA_1	173331	174548	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
PGOPPEHA_1	171748	173211	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
PGOPPEHA_1	173334	174548	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
PGOPPEHA_1	171751	173211	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
PGOPPEHA_5	70513	71228	STER_RS07085	0.0	Capsule	Immune modulation	96.51	99.86	WP_011681442
PGOPPEHA_5	67323	68576	STER_RS07100	0.0	Capsule	Immune modulation	95.14	99.44	WP_011681445
PGOPPEHA_5	66353	67204	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
PGOPPEHA_5	69543	70511	STER_RS07090	0.0	Capsule	Immune modulation	94.84	100.00	WP_011681443
PGOPPEHA_12	55059	56426	STU_RS14630	0.0	Capsule	Immune modulation	94.15	100.00	WP_011226045
PGOPPEHA_12	55059	56424	STER_RS05300	0.0	Capsule	Immune modulation	94.14	99.85	WP_011681173
PGOPPEHA_12	51359	52819	STER_RS05320	0.0	Capsule	Immune modulation	93.70	100.00	WP_011681177
PGOPPEHA_12	51359	52819	STU_RS14650	0.0	Capsule	Immune modulation	93.63	100.21	WP_011226049
PGOPPEHA_12	54262	55002	STER_RS05305	0.0	Capsule	Immune modulation	93.52	100.00	WP_011681174
PGOPPEHA_5	71574	72344	STER_RS07075	0.0	Capsule	Immune modulation	93.26	99.23	WP_011681440
PGOPPEHA_12	51359	52819	STR_RS05265	0.0	Capsule	Immune modulation	92.88	100.21	WP_041827043
PGOPPEHA_12	54262	55002	STU_RS14635	0.0	Capsule	Immune modulation	92.85	100.00	WP_011226046
PGOPPEHA_12	54262	54997	STR_RS05250	0.0	Capsule	Immune modulation	92.25	98.13	WP_011227246
PGOPPEHA_3	122682	123275	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
PGOPPEHA_12	52820	53551	STU_RS14645	0.0	Capsule	Immune modulation	91.67	100.00	WP_011226048
PGOPPEHA_3	122682	123275	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
PGOPPEHA_3	122682	123275	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
PGOPPEHA_3	123275	124144	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
PGOPPEHA_12	52820	53551	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
PGOPPEHA_12	52820	53551	STR_RS05260	0.0	Capsule	Immune modulation	90.71	100.00	WP_011227248
PGOPPEHA_1	106421	108079	fbp54	0.0	FBPs	Adherence	90.66	99.94	WP_011227179
PGOPPEHA_22	19906	20745	cbpD	0.0	Autolysin	Exoenzyme	89.92	99.76	WP_011226733
PGOPPEHA_2	182664	183967	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
PGOPPEHA_12	53560	54252	STR_RS05255	0.0	Capsule	Immune modulation	87.90	99.86	WP_011227247
PGOPPEHA_12	53560	54252	STU_RS14640	0.0	Capsule	Immune modulation	87.90	99.86	WP_011226047
PGOPPEHA_29	14337	15347	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
PGOPPEHA_12	53560	54252	STER_RS05310	0.0	Capsule	Immune modulation	87.32	99.86	WP_011681175
PGOPPEHA_24	3852	4613	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
PGOPPEHA_3	121433	122479	rfbB	0.0	Capsule	Immune modulation	81.98	99.90	WP_009659423
PGOPPEHA_8	1949	3232	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
PGOPPEHA_24	1163	189	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
PGOPPEHA_24	12748	13821	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
PGOPPEHA_9	32064	29758	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
PGOPPEHA_11	55767	57248	SPD_0310	0.0	UPF0371 protein SPD_0310	93.52	100.00	ABJ54480
PGOPPEHA_24	32288	34534	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
PGOPPEHA_2	92870	93838	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
PGOPPEHA_22	4311	5282	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
PGOPPEHA_3	149525	147795	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
PGOPPEHA_5	52490	54478	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
PGOPPEHA_5	24152	25303	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
PGOPPEHA_18	25841	27319	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
PGOPPEHA_2	182664	183965	Eno	0.0	enolase	86.44	99.77	ABP90468
PGOPPEHA_18	41195	43087	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
PGOPPEHA_1	1957	248	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
PGOPPEHA_36	2043	952	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
PGOPPEHA_6	28926	29936	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
PGOPPEHA_1	133979	132618	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
PGOPPEHA_2	168248	169138	bglB	1.99e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
PGOPPEHA_1	41138	40188	SP_0676	3.73e-170	transcription facot	81.39	98.45	AAK74821
PGOPPEHA_24	34724	35581	metF	1.53e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
PGOPPEHA_12	6586	7290	covR	2.99e-127	responder protein	85.53	100.00	AAK71319
PGOPPEHA_16	27247	27918	rr01	3.62e-126	response regulator	83.93	99.56	CAB54566
PGOPPEHA_1	5924	6595	ciaR	2.25e-125	two component system response regulator	86.16	99.12	AIK75708
PGOPPEHA_1	5924	6592	CiaR	4.15e-125	two-component response regulator	87.44	99.55	AAK74935
PGOPPEHA_12	6586	7290	walR	6.80e-121	DNA-binding response regulator	82.13	100.00	ANC99504
PGOPPEHA_4	74293	74979	CovR	2.83e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
PGOPPEHA_36	779	384	SpxA2	4.67e-77	transcriptional regulator	91.67	100.00	ERL21461
PGOPPEHA_1	145447	145848	SpxA1	6.00e-70	transcriptional regulator	82.84	100.00	ERL19273
PGOPPEHA_25	6204	5791	GrpE	1.97e-68	protein grpE	81.88	80.59	ABP89267
PGOPPEHA_4	97505	97792	spr0479	3.43e-48	essential gene	85.42	98.97	AAK99283
PGOPPEHA_2	50593	50847	spr1327	8.38e-45	essential gene	92.94	100.00	AAL00131
PGOPPEHA_20	2731	2994	spr0175	2.49e-43	pathogenitcity related	85.23	100.00	AAK98979
PGOPPEHA_20	3557	3823	spr0177	3.47e-42	essential gene	83.15	88.12	AAK98981
PGOPPEHA_8	3399	3890	RopE (M5005_Spy_1611)	4.18e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
PGOPPEHA_9	32064	29764	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
PGOPPEHA_6	65642	64623	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451