Genome ID：GCA_047463075.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	34	39.50

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
KMKPCFBF_1	300568	301785	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
KMKPCFBF_1	301905	303368	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
KMKPCFBF_1	300568	301782	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
KMKPCFBF_1	301905	303365	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KMKPCFBF_2	211814	212529	STER_RS07085	0.0	Capsule	Immune modulation	96.51	99.86	WP_011681442
KMKPCFBF_2	208624	209877	STER_RS07100	0.0	Capsule	Immune modulation	95.14	99.44	WP_011681445
KMKPCFBF_2	207654	208505	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
KMKPCFBF_2	210844	211812	STER_RS07090	0.0	Capsule	Immune modulation	94.84	100.00	WP_011681443
KMKPCFBF_1	648038	649403	STER_RS05300	0.0	Capsule	Immune modulation	94.14	99.85	WP_011681173
KMKPCFBF_1	644337	645797	STU_RS14650	0.0	Capsule	Immune modulation	94.05	100.07	WP_011226049
KMKPCFBF_1	647240	647980	STER_RS05305	0.0	Capsule	Immune modulation	93.93	100.00	WP_011681174
KMKPCFBF_1	644337	645797	STER_RS05320	0.0	Capsule	Immune modulation	93.84	100.00	WP_011681177
KMKPCFBF_1	648038	649405	STU_RS14630	0.0	Capsule	Immune modulation	93.79	100.00	WP_011226045
KMKPCFBF_2	212875	213645	STER_RS07075	0.0	Capsule	Immune modulation	93.26	99.23	WP_011681440
KMKPCFBF_1	644337	645797	STR_RS05265	0.0	Capsule	Immune modulation	93.16	100.07	WP_041827043
KMKPCFBF_1	647240	647980	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
KMKPCFBF_1	647240	647975	STR_RS05250	0.0	Capsule	Immune modulation	92.66	98.13	WP_011227246
KMKPCFBF_1	645798	646529	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
KMKPCFBF_1	645798	646529	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
KMKPCFBF_1	472763	473356	STR_RS05880	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
KMKPCFBF_1	472763	473356	STER_RS06030	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
KMKPCFBF_1	472763	473356	STU_RS15260	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
KMKPCFBF_1	471894	472763	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
KMKPCFBF_1	645798	646529	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
KMKPCFBF_1	754894	756552	fbp54	0.0	FBPs	Adherence	90.66	99.94	WP_011227179
KMKPCFBF_7	14853	15863	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
KMKPCFBF_1	272464	273767	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
KMKPCFBF_1	646538	647230	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
KMKPCFBF_1	646538	647230	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
KMKPCFBF_1	646538	647230	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
KMKPCFBF_1	91625	92521	cbpD	0.0	Autolysin	Exoenzyme	84.66	93.19	WP_082302295
KMKPCFBF_1	473622	474668	rfbB	0.0	Capsule	Immune modulation	84.35	99.90	WP_002263087
KMKPCFBF_6	79968	80729	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
KMKPCFBF_10	1837	3120	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
KMKPCFBF_1	657556	658139	SPD_RS01775	4.71e-157	Capsule	Immune modulation	84.10	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KMKPCFBF_6	83417	84400	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
KMKPCFBF_6	71837	70764	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
KMKPCFBF_2	31165	28859	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
KMKPCFBF_4	74551	76032	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
KMKPCFBF_1	180287	181255	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
KMKPCFBF_6	52784	50538	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
KMKPCFBF_9	4366	5337	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
KMKPCFBF_6	141144	134671	PrtA	0.0	serine protease	91.35	100.61	ABJ55268
KMKPCFBF_1	446509	448239	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
KMKPCFBF_2	193791	195779	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
KMKPCFBF_2	165439	166590	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
KMKPCFBF_3	25881	27359	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
KMKPCFBF_1	272464	273765	Eno	0.0	enolase	86.44	99.77	ABP90468
KMKPCFBF_3	41239	43131	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
KMKPCFBF_6	47619	49328	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
KMKPCFBF_9	44416	45507	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KMKPCFBF_3	185762	184752	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
KMKPCFBF_1	739331	740692	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
KMKPCFBF_1	258045	258935	bglB	8.77e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
KMKPCFBF_6	8355	9305	SP_0676	2.41e-170	transcription facot	81.39	98.45	AAK74821
KMKPCFBF_6	50351	49494	metF	3.82e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
KMKPCFBF_1	598656	599360	covR	3.60e-126	responder protein	85.53	100.00	AAK71319
KMKPCFBF_6	43649	42978	ciaR	1.45e-125	two component system response regulator	86.16	99.12	AIK75708
KMKPCFBF_4	14018	13347	rr01	1.53e-125	response regulator	83.93	99.56	CAB54566
KMKPCFBF_6	43649	42981	CiaR	2.68e-125	two-component response regulator	87.44	99.55	AAK74935
KMKPCFBF_5	149719	150405	CovR	4.44e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
KMKPCFBF_1	598656	599360	walR	8.19e-120	DNA-binding response regulator	82.13	100.00	ANC99504
KMKPCFBF_9	45681	46076	SpxA2	4.55e-76	transcriptional regulator	91.67	100.00	ERL21461
KMKPCFBF_1	727864	727463	SpxA1	8.94e-69	transcriptional regulator	82.09	100.00	ERL19273
KMKPCFBF_8	48398	48811	GrpE	4.27e-68	protein grpE	81.88	80.59	ABP89267
KMKPCFBF_5	172930	173217	spr0479	5.38e-48	essential gene	85.42	98.97	AAK99283
KMKPCFBF_1	146785	147039	spr1327	1.31e-45	essential gene	95.29	100.00	AAL00131
KMKPCFBF_3	94245	93982	spr0175	1.11e-42	pathogenitcity related	85.23	100.00	AAK98979
KMKPCFBF_3	93421	93155	spr0177	2.46e-41	essential gene	83.15	88.12	AAK98981
KMKPCFBF_10	3287	3778	RopE (M5005_Spy_1611)	5.43e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
KMKPCFBF_2	31165	28865	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.36	98.08	MYN69560
KMKPCFBF_3	149351	150370	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451