Genome ID：GCA_047463255.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	16	35	38.54

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
GFMHCCIN_14	43392	44609	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
GFMHCCIN_14	44729	46192	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
GFMHCCIN_14	43392	44606	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
GFMHCCIN_14	44729	46189	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
GFMHCCIN_22	10021	10752	STR_RS05260	0.0	Capsule	Immune modulation	94.54	100.00	WP_011227248
GFMHCCIN_3	23795	24511	STER_RS07085	0.0	Capsule	Immune modulation	94.42	100.00	WP_011681442
GFMHCCIN_3	20219	21070	rfbD	0.0	Capsule	Immune modulation	94.37	100.00	WP_014621820
GFMHCCIN_22	10021	10752	STU_RS14645	0.0	Capsule	Immune modulation	93.85	100.00	WP_011226048
GFMHCCIN_22	10021	10752	STER_RS05315	0.0	Capsule	Immune modulation	93.58	100.00	WP_011681176
GFMHCCIN_3	24857	25627	STER_RS07075	0.0	Capsule	Immune modulation	92.35	99.23	WP_011681440
GFMHCCIN_22	10753	12213	STER_RS05320	0.0	Capsule	Immune modulation	91.26	99.86	WP_011681177
GFMHCCIN_28	7699	8292	STR_RS05880	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
GFMHCCIN_28	7699	8292	STER_RS06030	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
GFMHCCIN_28	7699	8292	STU_RS15260	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
GFMHCCIN_22	10753	12213	STU_RS14650	0.0	Capsule	Immune modulation	90.65	100.00	WP_011226049
GFMHCCIN_21	39530	41187	fbp54	0.0	FBPs	Adherence	90.30	99.88	WP_011227179
GFMHCCIN_22	10753	12213	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
GFMHCCIN_17	12140	13045	cbpD	0.0	Autolysin	Exoenzyme	89.96	93.50	WP_082302295
GFMHCCIN_22	9320	10012	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
GFMHCCIN_22	9320	10012	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
GFMHCCIN_22	9320	10012	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
GFMHCCIN_14	22415	23718	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
GFMHCCIN_25	16125	17138	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
GFMHCCIN_6	37835	38596	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
GFMHCCIN_28	6383	7429	rfbB	0.0	Capsule	Immune modulation	83.59	99.90	WP_002263087
GFMHCCIN_40	8443	9726	tig/ropA	0.0	Trigger factor	Stress survival	80.76	99.61	WP_000107753
GFMHCCIN_28	8292	9161	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
GFMHCCIN_22	8640	9310	STU_RS14635	5.68e-150	Capsule	Immune modulation	81.13	90.28	WP_011226046
GFMHCCIN_22	8640	9310	STER_RS05305	2.64e-148	Capsule	Immune modulation	80.98	90.28	WP_011681174
GFMHCCIN_22	8640	9310	STR_RS05250	2.68e-138	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
GFMHCCIN_6	35146	34163	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
GFMHCCIN_6	46734	47807	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
GFMHCCIN_2	87528	85222	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
GFMHCCIN_15	35357	34389	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
GFMHCCIN_8	58676	57195	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
GFMHCCIN_6	65794	68040	metE	0.0	methionine biosynthesis enzymes	92.79	100.00	AAK74738
GFMHCCIN_23	37635	36664	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
GFMHCCIN_49	3567	1837	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
GFMHCCIN_3	5086	7074	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
GFMHCCIN_7	25708	24557	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
GFMHCCIN_16	7020	8498	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
GFMHCCIN_14	22415	23716	Eno	0.0	enolase	86.44	99.77	ABP90468
GFMHCCIN_16	22370	24262	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
GFMHCCIN_23	1924	833	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
GFMHCCIN_6	70958	69249	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
GFMHCCIN_21	25768	27129	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
GFMHCCIN_5	92049	91039	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
GFMHCCIN_14	8009	8899	bglB	8.01e-179	putative phospho--glucosidase	87.88	99.66	AAK33487
GFMHCCIN_6	110927	109977	SP_0676	1.75e-170	transcription facot	81.39	98.45	AAK74821
GFMHCCIN_6	68230	69087	metF	1.35e-168	methionine biosynthesis enzymes	86.71	99.31	AAK74739
GFMHCCIN_27	18523	19380	mtsA	8.84e-153	substrate-binding lipoprotein of manganese transporter	80.49	92.86	AIK76191
GFMHCCIN_3	20219	21040	GacA	2.32e-147	dTDP-4-dehydrorhamnose reductas	80.29	96.48	AAZ51220
GFMHCCIN_12	31486	30815	rr01	1.54e-127	response regulator	84.82	99.56	CAB54566
GFMHCCIN_22	44520	43816	covR	2.80e-127	responder protein	85.53	100.00	AAK71319
GFMHCCIN_6	75623	76294	ciaR	1.14e-125	two component system response regulator	86.16	99.12	AIK75708
GFMHCCIN_6	75623	76291	CiaR	2.11e-125	two-component response regulator	87.44	99.55	AAK74935
GFMHCCIN_1	53873	53187	CovR	1.58e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
GFMHCCIN_22	44520	43816	walR	2.48e-120	DNA-binding response regulator	81.70	100.00	ANC99504
GFMHCCIN_23	660	265	SpxA2	4.11e-76	transcriptional regulator	91.67	100.00	ERL21461
GFMHCCIN_21	14311	13910	SpxA1	2.86e-70	transcriptional regulator	82.09	100.00	ERL19273
GFMHCCIN_10	6663	6250	GrpE	5.78e-68	protein grpE	81.88	80.59	ABP89267
GFMHCCIN_1	30667	30380	spr0479	1.03e-47	essential gene	85.42	98.97	AAK99283
GFMHCCIN_30	4936	4682	spr1327	8.19e-45	essential gene	90.59	100.00	AAL00131
GFMHCCIN_5	1266	1003	spr0175	6.29e-43	pathogenitcity related	85.23	100.00	AAK98979
GFMHCCIN_5	441	175	spr0177	1.40e-41	essential gene	83.15	88.12	AAK98981
GFMHCCIN_40	8276	7785	RopE (M5005_Spy_1611)	5.08e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
GFMHCCIN_2	87528	85228	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
GFMHCCIN_5	55910	56929	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
GFMHCCIN_32	8985	8449	pnuC	6.33e-99	NAD salvage pathway importer	88.83	66.54	AAK75931