Genome ID：GCA_049310985.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	22	33	39.66

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HDCEGNDM_26	73897	74706	STU_RS16245	0.0	Capsule	Immune modulation	95.68	100.00	WP_002948020
HDCEGNDM_13	49228	50593	STER_RS05300	0.0	Capsule	Immune modulation	95.61	99.85	WP_011681173
HDCEGNDM_13	49226	50593	STU_RS14630	0.0	Capsule	Immune modulation	95.10	100.00	WP_011226045
HDCEGNDM_26	78052	78903	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
HDCEGNDM_13	50650	51390	STER_RS05305	0.0	Capsule	Immune modulation	94.20	100.00	WP_011681174
HDCEGNDM_13	52833	54293	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
HDCEGNDM_13	52833	54293	STU_RS14650	0.0	Capsule	Immune modulation	93.84	100.14	WP_011226049
HDCEGNDM_13	50650	51390	STU_RS14635	0.0	Capsule	Immune modulation	93.66	100.00	WP_011226046
HDCEGNDM_13	52833	54293	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
HDCEGNDM_13	50655	51390	STR_RS05250	0.0	Capsule	Immune modulation	93.21	98.13	WP_011227246
HDCEGNDM_26	69856	71640	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
HDCEGNDM_13	52101	52832	STU_RS14645	0.0	Capsule	Immune modulation	92.35	100.00	WP_011226048
HDCEGNDM_26	72692	73897	STU_RS16240	0.0	Capsule	Immune modulation	92.21	100.00	WP_011226326
HDCEGNDM_13	223545	224138	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
HDCEGNDM_26	75643	76791	STU_RS16255	0.0	Capsule	Immune modulation	91.91	100.00	WP_041828290
HDCEGNDM_13	223545	224138	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
HDCEGNDM_13	223545	224138	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
HDCEGNDM_13	52101	52832	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
HDCEGNDM_26	71637	72671	STU_RS16235	0.0	Capsule	Immune modulation	91.67	99.05	WP_002948022
HDCEGNDM_26	74690	75646	STU_RS16250	0.0	Capsule	Immune modulation	91.64	100.00	WP_011226328
HDCEGNDM_13	224138	225007	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
HDCEGNDM_13	52101	52832	STR_RS05260	0.0	Capsule	Immune modulation	91.39	100.00	WP_011227248
HDCEGNDM_20	66521	68179	fbp54	0.0	FBPs	Adherence	91.08	99.94	WP_011227179
HDCEGNDM_13	602413	603318	cbpD	0.0	Autolysin	Exoenzyme	89.51	93.50	WP_082302295
HDCEGNDM_13	51400	52092	STR_RS05255	0.0	Capsule	Immune modulation	88.91	99.86	WP_011227247
HDCEGNDM_13	51400	52092	STU_RS14640	0.0	Capsule	Immune modulation	88.91	99.86	WP_011226047
HDCEGNDM_21	13966	14976	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
HDCEGNDM_13	409169	410472	eno	0.0	Streptococcal enolase	Exoenzyme	88.40	99.54	WP_000022832
HDCEGNDM_13	51400	52092	STER_RS05310	0.0	Capsule	Immune modulation	87.18	99.86	WP_011681175
HDCEGNDM_13	222297	223343	rfbB	0.0	Capsule	Immune modulation	84.06	99.90	WP_002263087
HDCEGNDM_20	210930	211691	srtA	0.0	Sortase A	Exoenzyme	83.77	99.74	-
HDCEGNDM_7	31140	32423	tig/ropA	0.0	Trigger factor	Stress survival	80.76	99.61	WP_000107753
HDCEGNDM_13	37813	38396	SPD_RS01775	1.84e-150	Capsule	Immune modulation	83.42	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HDCEGNDM_20	214378	215361	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
HDCEGNDM_20	202800	201727	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
HDCEGNDM_21	143550	141244	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
HDCEGNDM_20	320663	322144	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
HDCEGNDM_20	183744	181498	metE	0.0	methionine biosynthesis enzymes	92.66	100.00	AAK74738
HDCEGNDM_13	516832	515864	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
HDCEGNDM_6	4386	5357	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HDCEGNDM_13	250389	248659	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HDCEGNDM_26	92339	90351	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
HDCEGNDM_26	128372	127221	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
HDCEGNDM_32	45394	43916	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
HDCEGNDM_13	410472	409171	Eno	0.0	enolase	86.44	99.77	ABP90468
HDCEGNDM_32	30073	28181	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.10	98.90	ABP91129
HDCEGNDM_20	178577	180286	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
HDCEGNDM_31	2888	3979	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HDCEGNDM_28	90282	89272	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HDCEGNDM_20	41198	42559	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
HDCEGNDM_13	424882	423992	bglB	6.90e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
HDCEGNDM_20	137678	138628	SP_0676	6.75e-170	transcription facot	81.39	98.45	AAK74821
HDCEGNDM_20	181308	180451	metF	3.35e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
HDCEGNDM_13	97351	96647	covR	1.72e-131	responder protein	85.53	100.00	AAK71319
HDCEGNDM_20	277267	276596	rr01	2.88e-127	response regulator	85.27	99.56	CAB54566
HDCEGNDM_20	174609	173938	ciaR	4.06e-125	two component system response regulator	86.16	99.12	AIK75708
HDCEGNDM_20	174609	173941	CiaR	7.51e-125	two-component response regulator	87.44	99.55	AAK74935
HDCEGNDM_13	97351	96647	walR	9.12e-122	DNA-binding response regulator	81.70	100.00	ANC99504
HDCEGNDM_33	54028	53342	CovR	1.35e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
HDCEGNDM_31	4155	4550	SpxA2	4.56e-77	transcriptional regulator	91.67	100.00	ERL21461
HDCEGNDM_20	29729	29328	SpxA1	4.69e-69	transcriptional regulator	82.09	100.00	ERL19273
HDCEGNDM_5	6678	6265	GrpE	9.75e-68	protein grpE	81.16	80.59	ABP89267
HDCEGNDM_33	30816	30529	spr0479	1.64e-48	essential gene	85.42	98.97	AAK99283
HDCEGNDM_13	550934	550680	spr1327	3.44e-44	essential gene	92.94	100.00	AAL00131
HDCEGNDM_28	1893	1630	spr0175	5.71e-43	pathogenitcity related	85.23	100.00	AAK98979
HDCEGNDM_28	1067	801	spr0177	7.96e-42	essential gene	83.15	88.12	AAK98981
HDCEGNDM_7	30973	30482	RopE (M5005_Spy_1611)	2.19e-72	probable DNA-directed RNA polymerase subunit delta	82.32	85.86	AAK34603
HDCEGNDM_21	143550	141250	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
HDCEGNDM_28	55162	56181	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451