Genome ID：GCA_900636435.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	24	30	38.42

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
MLHHEAKI_1	1682992	1683843	rfbD	0.0	Capsule	Immune modulation	95.19	100.00	WP_014621820
MLHHEAKI_1	1057102	1057842	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
MLHHEAKI_1	1057102	1057842	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
MLHHEAKI_1	1054199	1055659	STU_RS14650	0.0	Capsule	Immune modulation	94.11	100.14	WP_011226049
MLHHEAKI_1	1054199	1055659	STER_RS05320	0.0	Capsule	Immune modulation	94.05	99.93	WP_011681177
MLHHEAKI_1	1057899	1059266	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
MLHHEAKI_1	1057102	1057837	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
MLHHEAKI_1	1680620	1681891	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
MLHHEAKI_1	1057899	1059264	STER_RS05300	0.0	Capsule	Immune modulation	93.70	99.85	WP_011681173
MLHHEAKI_1	1679662	1680617	STU_RS16260	0.0	Capsule	Immune modulation	93.41	94.56	WP_011226330
MLHHEAKI_1	1054199	1055659	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
MLHHEAKI_1	1671010	1672794	STU_RS16230	0.0	Capsule	Immune modulation	92.61	99.94	WP_011226325
MLHHEAKI_1	1675844	1676800	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
MLHHEAKI_1	1676797	1677945	STU_RS16255	0.0	Capsule	Immune modulation	92.34	100.00	WP_041828290
MLHHEAKI_1	1675051	1675860	STU_RS16245	0.0	Capsule	Immune modulation	92.23	99.88	WP_002948020
MLHHEAKI_1	1673846	1675051	STU_RS16240	0.0	Capsule	Immune modulation	92.12	100.00	WP_011226326
MLHHEAKI_1	1055660	1056391	STU_RS14645	0.0	Capsule	Immune modulation	91.53	100.00	WP_011226048
MLHHEAKI_1	1672791	1673825	STU_RS16235	0.0	Capsule	Immune modulation	91.29	99.15	WP_002948022
MLHHEAKI_1	1055660	1056391	STER_RS05315	0.0	Capsule	Immune modulation	91.12	100.00	WP_011681176
MLHHEAKI_1	882707	883300	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
MLHHEAKI_1	38878	39717	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
MLHHEAKI_1	882707	883300	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
MLHHEAKI_1	882707	883300	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
MLHHEAKI_1	1163295	1164953	fbp54	0.0	FBPs	Adherence	90.84	99.94	WP_011227179
MLHHEAKI_1	1055660	1056391	STR_RS05260	0.0	Capsule	Immune modulation	90.57	100.00	WP_011227248
MLHHEAKI_1	881838	882707	rfbA	0.0	Capsule	Immune modulation	90.46	100.00	WP_011681286
MLHHEAKI_1	1990513	1991523	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.55	99.80	WP_002986042
MLHHEAKI_1	670366	671669	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
MLHHEAKI_1	1056400	1057092	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
MLHHEAKI_1	1056400	1057092	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
MLHHEAKI_1	1056400	1057092	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
MLHHEAKI_1	1301845	1302606	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
MLHHEAKI_1	883571	884617	rfbB	0.0	Capsule	Immune modulation	83.98	99.81	WP_002263087
MLHHEAKI_1	195146	196429	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
MLHHEAKI_1	1068405	1068990	SPD_RS01775	2.19e-139	Capsule	Immune modulation	82.28	96.53	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
MLHHEAKI_1	1305296	1306279	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.65	100.00	AAK75326
MLHHEAKI_1	1293709	1292636	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
MLHHEAKI_1	1866313	1868619	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
MLHHEAKI_1	1446317	1447798	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
MLHHEAKI_1	581535	582503	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
MLHHEAKI_1	1274649	1272403	metE	0.0	methionine biosynthesis enzymes	92.52	100.00	AAK74738
MLHHEAKI_1	24455	25426	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
MLHHEAKI_1	856461	858191	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
MLHHEAKI_1	1696057	1694069	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
MLHHEAKI_1	1724410	1723259	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
MLHHEAKI_1	2195070	2193592	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
MLHHEAKI_1	670366	671667	Eno	0.0	enolase	86.44	99.77	ABP90468
MLHHEAKI_1	2179737	2177845	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
MLHHEAKI_1	1269484	1271193	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
MLHHEAKI_1	61207	62298	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
MLHHEAKI_1	2046900	2047910	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
MLHHEAKI_1	1149532	1150893	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
MLHHEAKI_1	655947	656837	bglB	2.39e-176	putative phospho--glucosidase	87.20	99.66	AAK33487
MLHHEAKI_1	1272216	1271359	metF	5.57e-168	methionine biosynthesis enzymes	87.76	99.31	AAK74739
MLHHEAKI_1	1230217	1231167	SP_0676	5.69e-168	transcription facot	81.07	98.45	AAK74821
MLHHEAKI_1	1180793	1180008	pnuC	1.59e-148	NAD salvage pathway importer	87.02	97.40	AAK75931
MLHHEAKI_1	1376738	1376067	rr01	4.74e-126	response regulator	84.82	99.56	CAB54566
MLHHEAKI_1	1008538	1009242	covR	9.84e-126	responder protein	85.53	100.00	AAK71319
MLHHEAKI_1	1265517	1264846	ciaR	2.12e-124	two component system response regulator	86.16	99.12	AIK75708
MLHHEAKI_1	1265517	1264849	CiaR	3.91e-124	two-component response regulator	87.44	99.55	AAK74935
MLHHEAKI_1	1008538	1009242	walR	2.24e-119	DNA-binding response regulator	82.13	100.00	ANC99504
MLHHEAKI_1	339626	340312	CovR	4.83e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
MLHHEAKI_1	62472	62867	SpxA2	2.17e-74	transcriptional regulator	91.67	100.00	ERL21461
MLHHEAKI_1	1138067	1137666	SpxA1	4.52e-69	transcriptional regulator	82.84	100.00	ERL19273
MLHHEAKI_1	181525	181938	GrpE	1.72e-66	protein grpE	81.88	80.59	ABP89267
MLHHEAKI_1	196596	197087	RopE (M5005_Spy_1611)	1.07e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
MLHHEAKI_1	1866313	1868613	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
MLHHEAKI_1	2083334	2082315	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451