Genome ID：GCA_901875525.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	34	39.50

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
DDCBIDHL_33	69054	70271	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
DDCBIDHL_33	67471	68934	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
DDCBIDHL_33	69057	70271	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
DDCBIDHL_33	67474	68934	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
DDCBIDHL_11	135637	136488	rfbD	0.0	Capsule	Immune modulation	95.31	100.00	WP_014621820
DDCBIDHL_8	35454	36185	STR_RS05260	0.0	Capsule	Immune modulation	94.40	100.00	WP_011227248
DDCBIDHL_8	35454	36185	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
DDCBIDHL_8	35454	36185	STER_RS05315	0.0	Capsule	Immune modulation	93.44	100.00	WP_011681176
DDCBIDHL_11	128553	130309	STU_RS16230	0.0	Capsule	Immune modulation	92.54	98.43	WP_011226325
DDCBIDHL_11	133359	134315	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
DDCBIDHL_11	131361	132566	STU_RS16240	0.0	Capsule	Immune modulation	92.21	100.00	WP_011226326
DDCBIDHL_11	132566	133375	STU_RS16245	0.0	Capsule	Immune modulation	92.11	99.88	WP_002948020
DDCBIDHL_11	134312	135460	STU_RS16255	0.0	Capsule	Immune modulation	91.56	99.91	WP_041828290
DDCBIDHL_8	33993	35453	STER_RS05320	0.0	Capsule	Immune modulation	91.33	99.86	WP_011681177
DDCBIDHL_11	130306	131340	STU_RS16235	0.0	Capsule	Immune modulation	91.10	99.15	WP_002948022
DDCBIDHL_15	32249	32842	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
DDCBIDHL_22	49757	51415	fbp54	0.0	FBPs	Adherence	90.96	99.94	WP_011227179
DDCBIDHL_15	32249	32842	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
DDCBIDHL_15	32249	32842	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
DDCBIDHL_8	33993	35453	STU_RS14650	0.0	Capsule	Immune modulation	90.72	100.00	WP_011226049
DDCBIDHL_11	198729	199634	cbpD	0.0	Autolysin	Exoenzyme	90.07	93.50	WP_082302295
DDCBIDHL_8	33993	35453	STR_RS05265	0.0	Capsule	Immune modulation	90.03	100.00	WP_041827043
DDCBIDHL_8	36194	36886	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
DDCBIDHL_8	36194	36886	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
DDCBIDHL_8	36194	36886	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
DDCBIDHL_33	92386	93689	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
DDCBIDHL_12	28672	29685	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
DDCBIDHL_3	48116	48877	srtA	0.0	Sortase A	Exoenzyme	85.21	99.74	-
DDCBIDHL_15	30933	31979	rfbB	0.0	Capsule	Immune modulation	83.49	99.90	WP_002263087
DDCBIDHL_19	1783	3066	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
DDCBIDHL_15	32842	33711	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
DDCBIDHL_8	36896	37566	STU_RS14635	6.30e-150	Capsule	Immune modulation	81.13	90.28	WP_011226046
DDCBIDHL_8	36896	37566	STER_RS05305	2.93e-148	Capsule	Immune modulation	80.98	90.28	WP_011681174
DDCBIDHL_8	36896	37566	STR_RS05250	2.97e-138	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
DDCBIDHL_3	45427	44444	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
DDCBIDHL_3	57013	58086	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
DDCBIDHL_49	83833	86139	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
DDCBIDHL_17	10908	9427	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
DDCBIDHL_3	76075	78321	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
DDCBIDHL_9	41913	40945	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
DDCBIDHL_14	36624	35653	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
DDCBIDHL_1	7164	691	PrtA	0.0	serine protease	91.44	100.61	ABJ55268
DDCBIDHL_51	20206	18476	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
DDCBIDHL_10	3949	2798	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
DDCBIDHL_11	149473	147485	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
DDCBIDHL_48	25833	27311	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
DDCBIDHL_33	93689	92388	Eno	0.0	enolase	86.44	99.77	ABP90468
DDCBIDHL_48	41181	43073	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
DDCBIDHL_14	1892	801	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
DDCBIDHL_13	40607	42316	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
DDCBIDHL_22	35831	37192	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
DDCBIDHL_47	77179	76169	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
DDCBIDHL_33	108099	107209	bglB	1.53e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
DDCBIDHL_3	78511	79368	metF	2.91e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
DDCBIDHL_22	145533	146483	SP_0676	3.94e-170	transcription facot	81.39	98.45	AAK74821
DDCBIDHL_1	31315	30644	rr01	1.59e-127	response regulator	84.82	99.56	CAB54566
DDCBIDHL_8	1811	2515	covR	2.19e-127	responder protein	85.53	100.00	AAK71319
DDCBIDHL_13	35942	35271	ciaR	1.88e-125	two component system response regulator	85.71	99.12	AIK75708
DDCBIDHL_13	35942	35274	CiaR	2.33e-125	two-component response regulator	87.00	99.55	AAK74935
DDCBIDHL_8	1811	2515	walR	4.98e-121	DNA-binding response regulator	82.13	100.00	ANC99504
DDCBIDHL_44	70933	71619	CovR	1.04e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
DDCBIDHL_14	626	231	SpxA2	4.01e-76	transcriptional regulator	91.67	100.00	ERL21461
DDCBIDHL_22	24374	23973	SpxA1	9.35e-70	transcriptional regulator	82.09	100.00	ERL19273
DDCBIDHL_23	6581	6168	GrpE	1.45e-68	protein grpE	81.88	80.59	ABP89267
DDCBIDHL_44	94135	94422	spr0479	3.30e-48	essential gene	85.42	98.97	AAK99283
DDCBIDHL_24	16792	17046	spr1327	5.89e-47	essential gene	94.12	100.00	AAL00131
DDCBIDHL_48	81791	81528	spr0175	4.87e-43	pathogenitcity related	85.23	100.00	AAK98979
DDCBIDHL_48	80966	80700	spr0177	1.08e-41	essential gene	83.15	88.12	AAK98981
DDCBIDHL_19	3233	3724	RopE (M5005_Spy_1611)	1.31e-73	probable DNA-directed RNA polymerase subunit delta	83.54	85.86	AAK34603
DDCBIDHL_49	83833	86133	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.36	98.08	MYN69560
DDCBIDHL_47	40769	41788	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451