Genome ID：GCA_903890635.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	25	28	37.55

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
OPAJLCEP_1	131774	133714	tet(S)	ARO:3000192	tet(S)	99.84	100.78	L09756.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
OPAJLCEP_1	131789	133714	tet(S)	Doxycycline, Tetracycline, Minocycline	100.00	100.00	L09756

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
OPAJLCEP_1	131789	133711	tet(S)	tetracycline resistance ribosomal protection protein Tet(S)	EXACTX	100.00	100.00	WP_000691722.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
OPAJLCEP_1	1166695	1167288	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
OPAJLCEP_1	1166695	1167288	STER_RS06030	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
OPAJLCEP_1	1166695	1167288	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
OPAJLCEP_1	1382932	1383888	STU_RS16250	0.0	Capsule	Immune modulation	99.48	100.00	WP_011226328
OPAJLCEP_1	1167288	1168157	rfbA	0.0	Capsule	Immune modulation	99.42	100.00	WP_011681286
OPAJLCEP_1	913758	915416	fbp54	0.0	FBPs	Adherence	99.34	100.00	WP_011227179
OPAJLCEP_1	1382139	1382948	STU_RS16245	0.0	Capsule	Immune modulation	99.01	100.00	WP_002948020
OPAJLCEP_1	1030874	1031870	STU_RS14625*	0.0	Capsule	Immune modulation	99.00	100.00	-
OPAJLCEP_1	1035728	1036420	STU_RS14640	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226047
OPAJLCEP_1	1383885	1385033	STU_RS16255	0.0	Capsule	Immune modulation	98.87	100.00	WP_041828290
OPAJLCEP_1	1380934	1382139	STU_RS16240	0.0	Capsule	Immune modulation	98.76	100.00	WP_011226326
OPAJLCEP_1	1035728	1036420	STR_RS05255	0.0	Capsule	Immune modulation	98.70	100.00	WP_011227247
OPAJLCEP_1	1386741	1387703	STU_RS16260	0.0	Capsule	Immune modulation	98.65	95.25	WP_011226330
OPAJLCEP_1	1378066	1379850	STU_RS16230	0.0	Capsule	Immune modulation	98.60	100.00	WP_011226325
OPAJLCEP_1	43621	44460	cbpD	0.0	Autolysin	Exoenzyme	98.21	100.00	WP_011226733
OPAJLCEP_1	1037161	1038621	STER_RS05320	0.0	Capsule	Immune modulation	98.08	100.00	WP_011681177
OPAJLCEP_1	1206197	1206958	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
OPAJLCEP_1	1036429	1037160	STU_RS14645	0.0	Capsule	Immune modulation	97.40	100.00	WP_011226048
OPAJLCEP_1	1036429	1037160	STER_RS05315	0.0	Capsule	Immune modulation	97.13	100.00	WP_011681176
OPAJLCEP_1	1034978	1035718	STER_RS05305	0.0	Capsule	Immune modulation	97.03	100.00	WP_011681174
OPAJLCEP_1	1036429	1037160	STR_RS05260	0.0	Capsule	Immune modulation	97.00	100.00	WP_011227248
OPAJLCEP_1	1390080	1390931	rfbD	0.0	Capsule	Immune modulation	96.95	100.00	WP_014621820
OPAJLCEP_1	1037161	1038621	STU_RS14650	0.0	Capsule	Immune modulation	96.78	100.21	WP_011226049
OPAJLCEP_1	1034978	1035718	STU_RS14635	0.0	Capsule	Immune modulation	96.63	100.00	WP_011226046
OPAJLCEP_1	1034983	1035718	STR_RS05250	0.0	Capsule	Immune modulation	96.47	98.13	WP_011227246
OPAJLCEP_1	1037161	1038621	STR_RS05265	0.0	Capsule	Immune modulation	95.83	100.21	WP_041827043
OPAJLCEP_1	1379847	1380914	STU_RS16235	0.0	Capsule	Immune modulation	95.17	101.14	WP_002948022
OPAJLCEP_1	1032112	1033308	STU_RS14630	0.0	Capsule	Immune modulation	94.57	87.43	WP_011226045
OPAJLCEP_1	1032114	1033308	STER_RS05300	0.0	Capsule	Immune modulation	94.24	87.21	WP_011681173
OPAJLCEP_1	1111975	1112753	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	92.81	99.37	-
OPAJLCEP_1	1035728	1036420	STER_RS05310	0.0	Capsule	Immune modulation	90.62	100.00	WP_011681175
OPAJLCEP_1	1387706	1388977	STU_RS16265	0.0	Capsule	Immune modulation	90.18	99.69	WP_011226331
OPAJLCEP_1	671436	672739	eno	0.0	Streptococcal enolase	Exoenzyme	87.41	99.54	WP_000022832
OPAJLCEP_1	1777589	1778599	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.96	99.90	WP_002986042
OPAJLCEP_1	1165219	1166265	rfbB	0.0	Capsule	Immune modulation	83.40	99.90	WP_002263087
OPAJLCEP_1	157601	158884	tig/ropA	0.0	Trigger factor	Stress survival	80.92	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
OPAJLCEP_1	1209645	1210628	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
OPAJLCEP_1	778881	779954	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
OPAJLCEP_1	586096	587064	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
OPAJLCEP_1	1648449	1650581	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	91.86	AAK74619
OPAJLCEP_1	1273440	1274921	SPD_0310	0.0	UPF0371 protein SPD_0310	91.90	100.00	ABJ54480
OPAJLCEP_1	798745	800991	metE	0.0	methionine biosynthesis enzymes	91.72	100.00	AAK74738
OPAJLCEP_1	27140	28111	prsA2	0.0	ribose-phosphate pyrophosphokinase	89.81	100.00	ABF36968
OPAJLCEP_1	1507060	1505909	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
OPAJLCEP_1	1477602	1475614	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
OPAJLCEP_1	1193446	1191716	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.39	100.00	AAK34199
OPAJLCEP_1	2006452	2004974	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
OPAJLCEP_1	671436	672737	Eno	0.0	enolase	85.75	99.77	ABP90468
OPAJLCEP_1	64615	65706	recA	0.0	DNA recombination and repair	85.44	95.10	AAL00560
OPAJLCEP_1	1991713	1989821	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.10	98.90	ABP91129
OPAJLCEP_1	803916	802207	PGM	0.0	phosphoglucomutase	83.71	99.65	ACH87041
OPAJLCEP_1	1856909	1857919	pdh	0.0	pyruvate dehydrogenase	82.20	99.70	ABP91006
OPAJLCEP_1	947296	945935	mnmE	0.0	central tRNA-modifying GTPase	80.92	99.56	ABP90420
OPAJLCEP_1	1906475	1904583	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
OPAJLCEP_1	657004	657894	bglB	1.45e-178	putative phospho--glucosidase	88.89	99.66	AAK33487
OPAJLCEP_1	858988	858050	SP_0676	1.22e-166	transcription facot	81.15	97.20	AAK74821
OPAJLCEP_1	801183	802040	metF	3.60e-163	methionine biosynthesis enzymes	85.31	99.31	AAK74739
OPAJLCEP_1	1074699	1073995	covR	1.24e-128	responder protein	84.25	100.00	AAK71319
OPAJLCEP_1	1254461	1253790	rr01	4.50e-126	response regulator	84.82	99.56	CAB54566
OPAJLCEP_1	807871	808539	CiaR	6.15e-124	two-component response regulator	87.00	99.55	AAK74935
OPAJLCEP_1	807871	808542	ciaR	2.71e-122	two component system response regulator	85.27	99.12	AIK75708
OPAJLCEP_1	1074699	1073995	walR	5.99e-120	DNA-binding response regulator	81.28	100.00	ANC99504
OPAJLCEP_1	324147	324827	CovR	7.08e-117	serves to repress GAS virulence factor-encoding genes	81.06	99.12	ACE75886
OPAJLCEP_1	65889	66284	SpxA2	2.10e-72	transcriptional regulator	89.39	100.00	ERL21461
OPAJLCEP_1	159042	159542	RopE (M5005_Spy_1611)	3.86e-75	probable DNA-directed RNA polymerase subunit delta	82.04	87.43	AAK34603
OPAJLCEP_1	1648449	1650575	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.70	90.78	MYN69560
OPAJLCEP_1	1892035	1891016	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451