Genome ID：GCA_903891245.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	28	28	39.60

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HLHDPEDG_1	1087087	1087956	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
HLHDPEDG_1	1086494	1087087	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
HLHDPEDG_1	1300410	1301219	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
HLHDPEDG_1	1086494	1087087	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HLHDPEDG_1	1301203	1302159	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
HLHDPEDG_1	1302156	1303304	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
HLHDPEDG_1	1299205	1300410	STU_RS16240	0.0	Capsule	Immune modulation	99.67	100.00	WP_011226326
HLHDPEDG_1	1086494	1087087	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
HLHDPEDG_1	1306800	1307651	rfbD	0.0	Capsule	Immune modulation	99.65	100.00	WP_014621820
HLHDPEDG_1	43684	44523	cbpD	0.0	Autolysin	Exoenzyme	99.52	100.00	WP_011226733
HLHDPEDG_1	857267	858925	fbp54	0.0	FBPs	Adherence	99.52	100.00	WP_011227179
HLHDPEDG_1	1296349	1298133	STU_RS16230	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226325
HLHDPEDG_1	1298130	1299185	STU_RS16235	0.0	Capsule	Immune modulation	99.43	100.00	WP_002948022
HLHDPEDG_1	1303413	1304423	STU_RS16260	0.0	Capsule	Immune modulation	99.41	100.00	WP_011226330
HLHDPEDG_1	964903	965634	STER_RS05315	0.0	Capsule	Immune modulation	99.04	100.00	WP_011681176
HLHDPEDG_1	965635	967095	STER_RS05320	0.0	Capsule	Immune modulation	98.97	100.00	WP_011681177
HLHDPEDG_1	1031598	1032386	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.36	99.75	-
HLHDPEDG_1	964903	965634	STR_RS05260	0.0	Capsule	Immune modulation	98.09	100.00	WP_011227248
HLHDPEDG_1	964903	965634	STU_RS14645	0.0	Capsule	Immune modulation	97.95	100.00	WP_011226048
HLHDPEDG_1	1123279	1124040	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
HLHDPEDG_1	1304426	1305697	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
HLHDPEDG_1	965635	967095	STU_RS14650	0.0	Capsule	Immune modulation	97.26	100.21	WP_011226049
HLHDPEDG_1	963452	964192	STU_RS14635	0.0	Capsule	Immune modulation	97.17	100.00	WP_011226046
HLHDPEDG_1	963452	964192	STER_RS05305	0.0	Capsule	Immune modulation	96.76	100.00	WP_011681174
HLHDPEDG_1	965635	967095	STR_RS05265	0.0	Capsule	Immune modulation	96.72	100.21	WP_041827043
HLHDPEDG_1	960790	961786	STU_RS14625*	0.0	Capsule	Immune modulation	96.69	100.00	-
HLHDPEDG_1	963457	964192	STR_RS05250	0.0	Capsule	Immune modulation	96.20	98.13	WP_011227246
HLHDPEDG_1	962028	963395	STU_RS14630	0.0	Capsule	Immune modulation	95.54	100.00	WP_011226045
HLHDPEDG_1	964202	964894	STR_RS05255	0.0	Capsule	Immune modulation	95.40	99.86	WP_011227247
HLHDPEDG_1	964202	964894	STU_RS14640	0.0	Capsule	Immune modulation	95.40	99.86	WP_011226047
HLHDPEDG_1	962030	963395	STER_RS05300	0.0	Capsule	Immune modulation	94.88	99.85	WP_011681173
HLHDPEDG_1	964202	964894	STER_RS05310	0.0	Capsule	Immune modulation	89.75	100.00	WP_011681175
HLHDPEDG_1	596066	597369	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
HLHDPEDG_1	1594822	1595832	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.54	99.41	WP_002986042
HLHDPEDG_1	148356	149639	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
HLHDPEDG_1	1085019	1086065	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
HLHDPEDG_1	960332	960781	STU_RS14620	2.83e-177	Capsule	Immune modulation	92.00	100.00	WP_011226042
HLHDPEDG_1	950746	951329	SPD_RS01775	2.28e-148	Capsule	Immune modulation	83.25	96.20	WP_001819836
HLHDPEDG_1	959971	960332	STU_RS14615	1.17e-81	Capsule	Immune modulation	82.51	73.87	WP_011226041

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HLHDPEDG_1	1126727	1127710	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
HLHDPEDG_1	702850	703923	MntE	0.0	manganese homeostasis	94.13	99.72	ABF32167
HLHDPEDG_1	512385	513353	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
HLHDPEDG_1	1471898	1474201	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
HLHDPEDG_1	1196630	1198111	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
HLHDPEDG_1	732660	734906	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
HLHDPEDG_1	64187	65188	recA	0.0	DNA recombination and repair	91.02	86.08	AAL00560
HLHDPEDG_1	27202	28173	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
HLHDPEDG_1	1358133	1356982	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
HLHDPEDG_1	1322640	1320652	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
HLHDPEDG_1	1110531	1108801	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
HLHDPEDG_1	1789825	1788347	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
HLHDPEDG_1	596066	597367	Eno	0.0	enolase	86.21	99.77	ABP90468
HLHDPEDG_1	1774636	1772744	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
HLHDPEDG_1	737831	736122	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
HLHDPEDG_1	1636814	1637824	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HLHDPEDG_1	882340	880979	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
HLHDPEDG_1	1687082	1685190	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
HLHDPEDG_1	581631	582521	bglB	1.29e-177	putative phospho--glucosidase	88.55	99.66	AAK33487
HLHDPEDG_1	795793	794858	SP_0676	7.18e-168	transcription facot	81.73	96.89	AAK74821
HLHDPEDG_1	735098	735955	metF	1.49e-164	methionine biosynthesis enzymes	86.36	99.31	AAK74739
HLHDPEDG_1	1003916	1003212	covR	4.26e-131	responder protein	85.53	100.00	AAK71319
HLHDPEDG_1	1177655	1176984	rr01	2.92e-124	response regulator	83.93	99.56	CAB54566
HLHDPEDG_1	1003916	1003212	walR	1.79e-121	DNA-binding response regulator	82.13	100.00	ANC99504
HLHDPEDG_1	302817	303503	CovR	3.00e-118	serves to repress GAS virulence factor-encoding genes	81.22	100.00	ACE75886
HLHDPEDG_1	741785	742453	CiaR	1.96e-117	two-component response regulator	84.31	99.55	AAK74935
HLHDPEDG_1	741785	742456	ciaR	1.93e-115	two component system response regulator	82.14	99.12	AIK75708
HLHDPEDG_1	65461	65856	SpxA2	1.13e-73	transcriptional regulator	90.15	100.00	ERL21461
HLHDPEDG_1	149797	150297	RopE (M5005_Spy_1611)	4.78e-75	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
HLHDPEDG_1	1471898	1474195	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
HLHDPEDG_1	1672675	1671656	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	95.88	100.00	ABJ55451