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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KGFKFCOI_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KGFKFCOI_00002	4.21e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KGFKFCOI_00003	9.82e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
KGFKFCOI_00004	1.98e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KGFKFCOI_00005	2.79e-11	yqbO1	-	-	S	-	-	-	Domain of unknown function (DUF370)
KGFKFCOI_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGFKFCOI_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGFKFCOI_00008	2.72e-236	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_00009	1.98e-127	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
KGFKFCOI_00010	1.88e-194	yaaC	-	-	S	-	-	-	YaaC-like Protein
KGFKFCOI_00011	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KGFKFCOI_00012	7.18e-308	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KGFKFCOI_00013	3.3e-282	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGFKFCOI_00014	2.18e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KGFKFCOI_00015	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
KGFKFCOI_00016	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KGFKFCOI_00017	7.18e-301	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
KGFKFCOI_00018	3.54e-06	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KGFKFCOI_00019	0.0	nhaC_2	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
KGFKFCOI_00021	1.1e-300	-	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KGFKFCOI_00022	3.51e-294	-	2.5.1.48, 4.4.1.11	-	E	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KGFKFCOI_00023	1e-292	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KGFKFCOI_00024	2.89e-251	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KGFKFCOI_00025	0.0	gabD_2	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_00026	8.06e-96	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
KGFKFCOI_00027	8.69e-187	glnH	-	-	ET	ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ligated ion channel L-glutamate- and glycine-binding site
KGFKFCOI_00028	1.23e-141	glnP	-	-	E	ko:K02029,ko:K10037,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Polar amino acid ABC transporter, inner membrane subunit
KGFKFCOI_00029	3.01e-165	-	3.6.3.21	-	E	ko:K02028,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
KGFKFCOI_00030	4.05e-244	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00031	4.75e-247	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00032	3.19e-214	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00033	3.86e-205	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00034	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_00036	3.92e-115	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KGFKFCOI_00037	1.8e-136	clpP1	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGFKFCOI_00038	2.08e-157	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
KGFKFCOI_00039	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGFKFCOI_00040	4.53e-51	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KGFKFCOI_00041	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KGFKFCOI_00042	6.78e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KGFKFCOI_00043	2.37e-27	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
KGFKFCOI_00044	3.47e-267	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
KGFKFCOI_00045	7.96e-19	-	-	-	-	-	-	-	-
KGFKFCOI_00046	0.0	cckA	2.7.13.3	-	T	ko:K02482	-	ko00000,ko01000,ko01001,ko02022	GAF domain
KGFKFCOI_00047	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
KGFKFCOI_00048	1.5e-256	adhA	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KGFKFCOI_00049	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KGFKFCOI_00050	2.83e-236	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGFKFCOI_00052	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
KGFKFCOI_00053	2.23e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KGFKFCOI_00054	1.19e-71	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_00055	2.59e-234	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KGFKFCOI_00056	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
KGFKFCOI_00057	2.97e-60	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KGFKFCOI_00058	1.14e-175	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
KGFKFCOI_00059	1.29e-58	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
KGFKFCOI_00060	7.25e-206	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KGFKFCOI_00061	3.04e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
KGFKFCOI_00062	5.2e-226	-	-	-	S	-	-	-	NurA
KGFKFCOI_00063	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
KGFKFCOI_00064	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KGFKFCOI_00065	5.07e-108	-	-	-	K	-	-	-	DNA-binding transcription factor activity
KGFKFCOI_00066	6.03e-240	pelB	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Amb_all
KGFKFCOI_00068	0.0	-	-	-	S	-	-	-	ABC transporter
KGFKFCOI_00069	4.01e-154	-	-	-	T	-	-	-	protein histidine kinase activity
KGFKFCOI_00070	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
KGFKFCOI_00071	1.98e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
KGFKFCOI_00072	2.72e-286	yabE	-	-	T	-	-	-	protein conserved in bacteria
KGFKFCOI_00073	9.52e-149	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KGFKFCOI_00074	4.85e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KGFKFCOI_00075	4.38e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
KGFKFCOI_00076	4.02e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_00077	1.8e-34	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
KGFKFCOI_00078	2.35e-211	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KGFKFCOI_00079	2.69e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KGFKFCOI_00080	9.96e-82	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
KGFKFCOI_00081	2.26e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KGFKFCOI_00082	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KGFKFCOI_00083	6.02e-219	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGFKFCOI_00084	1.95e-141	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KGFKFCOI_00085	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KGFKFCOI_00086	7.35e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
KGFKFCOI_00087	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KGFKFCOI_00088	2.3e-123	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
KGFKFCOI_00089	2.11e-139	-	-	-	S	-	-	-	Yip1 domain
KGFKFCOI_00090	3.02e-254	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KGFKFCOI_00091	1.2e-116	-	-	-	S	-	-	-	Yip1 domain
KGFKFCOI_00092	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGFKFCOI_00093	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KGFKFCOI_00094	2.69e-43	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KGFKFCOI_00095	1.02e-153	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
KGFKFCOI_00096	3.01e-226	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGFKFCOI_00097	1.12e-114	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_00098	5.82e-255	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KGFKFCOI_00099	9.86e-135	-	-	-	S	-	-	-	SNARE associated Golgi protein
KGFKFCOI_00100	6.77e-71	yabP	-	-	S	-	-	-	Sporulation protein YabP
KGFKFCOI_00101	1.33e-94	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
KGFKFCOI_00102	1.73e-80	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KGFKFCOI_00103	7.4e-93	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
KGFKFCOI_00105	7.22e-285	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
KGFKFCOI_00106	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
KGFKFCOI_00107	2.67e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
KGFKFCOI_00108	5.96e-226	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KGFKFCOI_00109	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KGFKFCOI_00110	2.21e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
KGFKFCOI_00111	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KGFKFCOI_00112	3.69e-183	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KGFKFCOI_00113	3.73e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KGFKFCOI_00114	1.13e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KGFKFCOI_00115	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KGFKFCOI_00116	2.26e-141	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
KGFKFCOI_00117	4.52e-200	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
KGFKFCOI_00118	7.44e-192	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KGFKFCOI_00119	7.65e-83	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KGFKFCOI_00120	1.3e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KGFKFCOI_00121	1.86e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGFKFCOI_00122	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KGFKFCOI_00133	1.66e-89	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KGFKFCOI_00134	4.37e-124	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
KGFKFCOI_00135	6.55e-251	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KGFKFCOI_00136	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
KGFKFCOI_00137	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KGFKFCOI_00138	4.09e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KGFKFCOI_00139	1.18e-253	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
KGFKFCOI_00140	7.39e-156	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KGFKFCOI_00141	1.33e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KGFKFCOI_00142	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGFKFCOI_00143	9.81e-157	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
KGFKFCOI_00144	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KGFKFCOI_00145	3.61e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KGFKFCOI_00146	2.3e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGFKFCOI_00147	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
KGFKFCOI_00148	4.15e-153	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
KGFKFCOI_00149	2.37e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KGFKFCOI_00150	1.83e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KGFKFCOI_00151	1.19e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KGFKFCOI_00152	4.64e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KGFKFCOI_00153	8.48e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KGFKFCOI_00154	1.27e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KGFKFCOI_00155	2.15e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
KGFKFCOI_00156	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFKFCOI_00157	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFKFCOI_00158	1.84e-47	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
KGFKFCOI_00159	4.33e-95	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KGFKFCOI_00160	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KGFKFCOI_00161	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KGFKFCOI_00162	7.02e-288	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KGFKFCOI_00163	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KGFKFCOI_00164	9.49e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KGFKFCOI_00165	5.45e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KGFKFCOI_00166	9.74e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KGFKFCOI_00167	3.58e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KGFKFCOI_00168	2.63e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KGFKFCOI_00169	8.5e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KGFKFCOI_00170	1.76e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KGFKFCOI_00171	3.79e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KGFKFCOI_00172	5.12e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KGFKFCOI_00173	2.17e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KGFKFCOI_00174	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KGFKFCOI_00175	7.7e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KGFKFCOI_00176	2.21e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KGFKFCOI_00177	2.66e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KGFKFCOI_00178	6.37e-125	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KGFKFCOI_00179	8.96e-79	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KGFKFCOI_00180	1.59e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KGFKFCOI_00181	7.06e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KGFKFCOI_00182	9.26e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KGFKFCOI_00183	4.17e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KGFKFCOI_00184	8.08e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KGFKFCOI_00185	9.44e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
KGFKFCOI_00186	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KGFKFCOI_00187	5.99e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KGFKFCOI_00188	8.92e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KGFKFCOI_00189	4.05e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KGFKFCOI_00190	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFKFCOI_00191	3.65e-78	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KGFKFCOI_00192	7.56e-209	cbiO	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFKFCOI_00193	1.63e-199	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFKFCOI_00194	6.03e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFKFCOI_00195	4.33e-189	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KGFKFCOI_00196	2.77e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KGFKFCOI_00197	4.45e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KGFKFCOI_00198	2.78e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
KGFKFCOI_00199	1.08e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_00201	3.81e-160	yhjR	-	-	S	-	-	-	Rubrerythrin
KGFKFCOI_00202	3.93e-19	-	-	-	-	-	-	-	-
KGFKFCOI_00205	3.65e-105	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
KGFKFCOI_00206	1.1e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
KGFKFCOI_00207	7.19e-197	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
KGFKFCOI_00208	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00209	1.67e-249	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KGFKFCOI_00210	7.65e-101	-	-	-	S	-	-	-	Bacterial PH domain
KGFKFCOI_00211	2.06e-130	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
KGFKFCOI_00212	1.61e-225	-	-	-	-	-	-	-	-
KGFKFCOI_00213	8.19e-134	-	-	-	-	-	-	-	-
KGFKFCOI_00214	6.68e-96	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
KGFKFCOI_00215	3.54e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
KGFKFCOI_00216	3.05e-185	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
KGFKFCOI_00217	8.74e-47	-	-	-	-	-	-	-	-
KGFKFCOI_00220	2.13e-223	-	-	-	L	-	-	-	Endonuclease/Exonuclease/phosphatase family
KGFKFCOI_00221	1.14e-176	-	-	-	Q	-	-	-	Methyltransferase domain
KGFKFCOI_00222	3.65e-181	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_00223	8.52e-211	-	2.7.1.190	-	S	ko:K17910	-	ko00000,ko01000,ko01504	Protein of unknown function (DUF1679)
KGFKFCOI_00224	2.76e-152	-	-	-	O	-	-	-	Sap, sulfolipid-1-addressing protein
KGFKFCOI_00225	2.2e-95	-	-	-	-	-	-	-	-
KGFKFCOI_00226	2.8e-187	-	-	-	K	-	-	-	MerR family transcriptional regulator
KGFKFCOI_00227	6.03e-216	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KGFKFCOI_00228	1.89e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
KGFKFCOI_00229	1.51e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KGFKFCOI_00230	2.81e-74	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
KGFKFCOI_00231	1.51e-34	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
KGFKFCOI_00232	4.47e-98	-	-	-	-	-	-	-	-
KGFKFCOI_00233	0.0	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_00234	5.68e-95	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
KGFKFCOI_00235	2.96e-241	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_00236	6.83e-225	-	1.1.1.399, 1.1.1.95	-	C	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGFKFCOI_00237	4.58e-269	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
KGFKFCOI_00238	4.06e-213	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGFKFCOI_00239	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
KGFKFCOI_00240	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KGFKFCOI_00241	0.0	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
KGFKFCOI_00242	5.14e-143	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KGFKFCOI_00244	0.0	-	-	-	S	-	-	-	PepSY-associated TM region
KGFKFCOI_00245	5.89e-76	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
KGFKFCOI_00246	9.08e-234	-	-	-	S	-	-	-	amine dehydrogenase activity
KGFKFCOI_00247	2.66e-96	-	-	-	S	-	-	-	YtkA-like
KGFKFCOI_00249	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00250	2.91e-192	nikC	-	-	EP	ko:K02034,ko:K15586	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00251	6.43e-212	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00252	0.0	dppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KGFKFCOI_00253	1.48e-247	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
KGFKFCOI_00254	1.3e-141	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KGFKFCOI_00255	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_00256	1.95e-13	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
KGFKFCOI_00264	5.59e-128	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
KGFKFCOI_00265	8.4e-158	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KGFKFCOI_00266	6.84e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGFKFCOI_00267	3.74e-284	ybbR	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_00268	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KGFKFCOI_00269	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
KGFKFCOI_00271	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGFKFCOI_00272	4.36e-200	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00273	1.28e-224	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
KGFKFCOI_00274	2.58e-255	-	-	-	V	-	-	-	Beta-lactamase
KGFKFCOI_00276	0.0	-	-	-	S	-	-	-	Aminoglycoside phosphotransferase
KGFKFCOI_00277	1.43e-96	-	-	-	K	-	-	-	SpoVT / AbrB like domain
KGFKFCOI_00278	4.7e-283	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KGFKFCOI_00279	3.27e-183	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_00280	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KGFKFCOI_00281	1.5e-157	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
KGFKFCOI_00282	3.78e-248	-	-	-	T	-	-	-	Histidine kinase-like ATPases
KGFKFCOI_00283	4.32e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_00284	2.67e-292	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KGFKFCOI_00285	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KGFKFCOI_00286	2.12e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_00287	4.39e-76	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
KGFKFCOI_00288	2.17e-207	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_00289	2.4e-129	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGFKFCOI_00290	1.83e-230	-	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGFKFCOI_00291	7.03e-215	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
KGFKFCOI_00292	0.0	mecR1	-	-	KTV	ko:K02172,ko:K02547	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	BlaR1 peptidase M56
KGFKFCOI_00293	1.11e-84	blaI	-	-	K	ko:K02171,ko:K02546	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
KGFKFCOI_00294	2.62e-192	-	-	-	H	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
KGFKFCOI_00295	1.57e-83	-	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional
KGFKFCOI_00296	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
KGFKFCOI_00297	1.57e-263	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
KGFKFCOI_00298	1.64e-119	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_00299	5.31e-120	-	-	-	-	-	-	-	-
KGFKFCOI_00300	1.07e-195	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
KGFKFCOI_00301	1.85e-240	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KGFKFCOI_00302	4.3e-158	-	-	-	Q	-	-	-	SAM-dependent methyltransferase
KGFKFCOI_00303	1.27e-188	-	-	-	EG	-	-	-	EamA-like transporter family
KGFKFCOI_00304	3.63e-13	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
KGFKFCOI_00305	4.82e-89	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGFKFCOI_00306	7.32e-150	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_00307	4.71e-87	-	-	-	-	-	-	-	-
KGFKFCOI_00308	2.45e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
KGFKFCOI_00309	1.21e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KGFKFCOI_00310	2.05e-113	-	2.3.1.128	-	J	ko:K03789,ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_00311	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
KGFKFCOI_00312	3.84e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
KGFKFCOI_00313	5.78e-212	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
KGFKFCOI_00314	3.66e-274	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KGFKFCOI_00315	9.51e-129	flaR	-	-	F	-	-	-	topology modulation protein
KGFKFCOI_00316	4.11e-11	-	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
KGFKFCOI_00317	2.62e-111	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
KGFKFCOI_00318	4.83e-224	yueF	-	-	S	-	-	-	transporter activity
KGFKFCOI_00319	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KGFKFCOI_00320	2.41e-134	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KGFKFCOI_00321	4.83e-154	-	-	-	-	-	-	-	-
KGFKFCOI_00322	2.85e-134	-	-	-	-	-	-	-	-
KGFKFCOI_00324	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
KGFKFCOI_00325	1e-276	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
KGFKFCOI_00326	2.17e-108	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_00327	5.97e-241	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_00328	1.27e-224	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KGFKFCOI_00329	2.31e-182	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_00330	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KGFKFCOI_00331	3.25e-190	murR	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_00332	3.05e-235	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
KGFKFCOI_00333	3.66e-311	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
KGFKFCOI_00334	4.37e-218	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KGFKFCOI_00336	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
KGFKFCOI_00337	1.83e-203	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KGFKFCOI_00338	3.64e-306	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00339	1.14e-257	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
KGFKFCOI_00340	2.73e-240	purR15	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
KGFKFCOI_00341	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGFKFCOI_00342	7.75e-213	-	-	-	GK	-	-	-	ROK family
KGFKFCOI_00343	3.26e-199	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00344	2.97e-216	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
KGFKFCOI_00345	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00346	1.6e-209	manA3	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Endoglucanase
KGFKFCOI_00347	1.34e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
KGFKFCOI_00349	4.72e-127	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KGFKFCOI_00350	5.57e-71	fdx5	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
KGFKFCOI_00351	2.13e-28	-	-	-	-	-	-	-	-
KGFKFCOI_00352	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
KGFKFCOI_00353	3.19e-283	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KGFKFCOI_00354	4.73e-300	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
KGFKFCOI_00355	1.14e-224	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
KGFKFCOI_00356	3.47e-267	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
KGFKFCOI_00357	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_00358	0.0	-	-	-	EG	ko:K06295	-	ko00000	Bacillus/Clostridium GerA spore germination protein
KGFKFCOI_00359	2.63e-90	-	-	-	-	-	-	-	-
KGFKFCOI_00360	1.77e-116	ectA	2.3.1.178	-	K	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-2,4-diaminobutyric acid acetyltransferase
KGFKFCOI_00361	7.81e-316	ectB	2.6.1.76	-	E	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGFKFCOI_00362	1.59e-99	ectC	4.2.1.108	-	S	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
KGFKFCOI_00363	0.0	-	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
KGFKFCOI_00364	1.99e-196	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_00365	2.75e-211	-	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
KGFKFCOI_00366	2.4e-190	-	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
KGFKFCOI_00367	8.84e-254	-	3.6.3.20	-	P	ko:K05816	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00369	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGFKFCOI_00370	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
KGFKFCOI_00371	4.65e-276	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
KGFKFCOI_00372	2.6e-188	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_00373	8.28e-252	yneE	-	-	K	-	-	-	Arabinose-binding domain of AraC transcription regulator, N-term
KGFKFCOI_00374	2.2e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
KGFKFCOI_00375	1.47e-100	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
KGFKFCOI_00376	2.09e-308	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KGFKFCOI_00377	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
KGFKFCOI_00378	4.35e-262	ugpC	3.6.3.20	-	P	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00379	2.08e-211	ugpA	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
KGFKFCOI_00380	5.39e-184	ugpE	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter permease
KGFKFCOI_00381	3.09e-307	ugpB	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
KGFKFCOI_00382	3.56e-183	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KGFKFCOI_00383	7.67e-273	-	-	-	EGP	ko:K08162	-	ko00000,ko02000	Major Facilitator Superfamily
KGFKFCOI_00384	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00385	2.94e-194	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
KGFKFCOI_00386	1.02e-120	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KGFKFCOI_00387	1.33e-226	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00388	1.06e-200	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
KGFKFCOI_00389	3.96e-166	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KGFKFCOI_00390	9.42e-232	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_00391	4.12e-254	-	1.1.1.361	-	S	ko:K18652	-	ko00000,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_00392	4.08e-137	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
KGFKFCOI_00393	1.03e-264	-	-	-	-	-	-	-	-
KGFKFCOI_00394	6.82e-183	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_00395	8.47e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGFKFCOI_00396	5.5e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGFKFCOI_00397	5.18e-221	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KGFKFCOI_00398	0.0	-	-	-	E	-	-	-	amino acid
KGFKFCOI_00399	2.81e-232	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00400	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
KGFKFCOI_00401	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
KGFKFCOI_00402	1.21e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
KGFKFCOI_00403	9.68e-291	-	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
KGFKFCOI_00404	1.63e-197	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00405	1.27e-296	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_00406	1.16e-284	-	-	-	EM	-	-	-	Protein of unknown function (DUF993)
KGFKFCOI_00407	1.2e-201	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_00408	8.83e-289	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_00409	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_00410	4.05e-266	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
KGFKFCOI_00411	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00412	2.04e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00413	2.42e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00414	1.34e-258	-	-	-	I	-	-	-	Acyltransferase family
KGFKFCOI_00415	1.31e-304	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
KGFKFCOI_00416	1.02e-154	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_00417	1.85e-208	-	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_00418	3.41e-165	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
KGFKFCOI_00420	0.0	yesW	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
KGFKFCOI_00421	1.18e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00422	5.84e-189	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00423	2.52e-202	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00424	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
KGFKFCOI_00425	5.82e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00426	1.25e-204	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00427	7.77e-197	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00428	2.8e-142	-	-	-	S	-	-	-	Protein of unknown function, DUF624
KGFKFCOI_00429	9.7e-223	M1-640	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_00430	2.87e-217	rhaR1	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00431	4.82e-182	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
KGFKFCOI_00432	4.34e-281	egsA	1.1.1.261	-	C	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KGFKFCOI_00433	7.5e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KGFKFCOI_00434	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
KGFKFCOI_00435	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
KGFKFCOI_00436	2.39e-253	chvE	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_00437	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KGFKFCOI_00438	3.63e-253	araH	-	-	G	ko:K10544,ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGFKFCOI_00439	0.0	melA7	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
KGFKFCOI_00440	2.21e-168	-	-	-	-	-	-	-	-
KGFKFCOI_00442	3.11e-106	-	-	-	S	-	-	-	Putative small multi-drug export protein
KGFKFCOI_00443	4.73e-149	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KGFKFCOI_00444	1.06e-240	-	-	-	KTV	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
KGFKFCOI_00445	4.09e-63	ykkD_1	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
KGFKFCOI_00446	2.06e-78	ykkC_1	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
KGFKFCOI_00447	1.47e-130	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_00448	3.67e-310	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGFKFCOI_00449	2.48e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
KGFKFCOI_00450	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_00451	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KGFKFCOI_00452	9.35e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KGFKFCOI_00453	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KGFKFCOI_00454	7.41e-227	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KGFKFCOI_00455	6.31e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KGFKFCOI_00456	5.52e-208	iolJ	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KGFKFCOI_00457	2.99e-247	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_00458	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGFKFCOI_00459	2.39e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
KGFKFCOI_00460	5.4e-311	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
KGFKFCOI_00461	2.93e-86	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
KGFKFCOI_00462	2.98e-183	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00463	2.34e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00464	0.0	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00465	3.73e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00466	1.42e-248	-	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
KGFKFCOI_00467	3.33e-242	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_00468	2.78e-108	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_00469	4.36e-284	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
KGFKFCOI_00470	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
KGFKFCOI_00471	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
KGFKFCOI_00472	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
KGFKFCOI_00473	3.06e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
KGFKFCOI_00474	1.83e-101	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGFKFCOI_00475	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGFKFCOI_00476	7.44e-238	fruA2	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
KGFKFCOI_00477	1.08e-124	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
KGFKFCOI_00479	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGFKFCOI_00480	1.2e-203	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KGFKFCOI_00481	5.76e-134	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KGFKFCOI_00482	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
KGFKFCOI_00483	5.19e-308	-	-	-	E	-	-	-	Acyclic terpene utilisation family protein AtuA
KGFKFCOI_00484	1.27e-70	-	-	-	-	-	-	-	-
KGFKFCOI_00485	1.23e-292	-	-	-	C	ko:K03300	-	ko00000	Citrate transporter
KGFKFCOI_00486	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
KGFKFCOI_00487	4.09e-306	-	-	-	V	-	-	-	MatE
KGFKFCOI_00488	4.97e-39	-	-	-	-	-	-	-	-
KGFKFCOI_00489	1.06e-130	-	-	-	S	-	-	-	Tetratricopeptide repeat
KGFKFCOI_00490	1.05e-89	-	-	-	F	-	-	-	NUDIX domain
KGFKFCOI_00491	5.26e-172	-	-	-	-	-	-	-	-
KGFKFCOI_00492	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_00493	1.62e-37	-	-	-	-	-	-	-	-
KGFKFCOI_00494	1.22e-70	-	-	-	-	-	-	-	-
KGFKFCOI_00495	7.59e-245	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mannonate dehydratase activity
KGFKFCOI_00496	5.34e-245	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_00497	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_00498	9.73e-109	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
KGFKFCOI_00499	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_00500	1.22e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
KGFKFCOI_00501	6.32e-158	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
KGFKFCOI_00502	3.8e-60	-	-	-	UW	-	-	-	Collagen triple helix repeat (20 copies)
KGFKFCOI_00503	3.63e-272	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
KGFKFCOI_00504	7.98e-156	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
KGFKFCOI_00505	3.53e-275	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
KGFKFCOI_00506	4.66e-87	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
KGFKFCOI_00507	1.68e-107	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
KGFKFCOI_00508	3.76e-179	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
KGFKFCOI_00509	3.7e-60	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00510	1.37e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGFKFCOI_00511	5.36e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00512	0.0	gmuD	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGFKFCOI_00513	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
KGFKFCOI_00514	3.38e-119	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
KGFKFCOI_00515	7.36e-114	-	-	-	-	-	-	-	-
KGFKFCOI_00517	4.21e-39	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KGFKFCOI_00518	1.03e-126	-	-	-	M	-	-	-	3D domain
KGFKFCOI_00519	4.61e-293	-	-	-	JM	-	-	-	Bacterial transferase hexapeptide (six repeats)
KGFKFCOI_00520	1.14e-167	frlR3	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
KGFKFCOI_00521	3.29e-181	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
KGFKFCOI_00522	4.35e-12	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_00523	5.3e-83	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_00524	3.68e-311	ykoH	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_00525	1.04e-161	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KGFKFCOI_00526	4.23e-117	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KGFKFCOI_00527	1.42e-23	-	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KGFKFCOI_00528	0.000121	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KGFKFCOI_00530	0.0	-	-	-	I	-	-	-	radical SAM domain protein
KGFKFCOI_00531	0.0	-	1.3.98.3	-	H	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of porphyrin-containing compound
KGFKFCOI_00533	2.13e-180	yafE	-	-	Q	-	-	-	methyltransferase
KGFKFCOI_00535	6.1e-116	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
KGFKFCOI_00536	5.96e-284	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_00537	7.95e-133	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KGFKFCOI_00538	4.79e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
KGFKFCOI_00539	1.53e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
KGFKFCOI_00540	4.52e-203	-	-	-	-	-	-	-	-
KGFKFCOI_00541	2.94e-171	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
KGFKFCOI_00542	2.57e-223	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
KGFKFCOI_00543	5.27e-169	-	-	-	M	-	-	-	Glycosyl transferase family 2
KGFKFCOI_00544	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGFKFCOI_00545	3.19e-35	ybbJ	-	-	K	-	-	-	acetyltransferase
KGFKFCOI_00546	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KGFKFCOI_00547	6.43e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
KGFKFCOI_00548	1.13e-36	-	-	-	-	-	-	-	-
KGFKFCOI_00549	3.63e-309	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
KGFKFCOI_00550	5.2e-145	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
KGFKFCOI_00551	1.61e-169	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
KGFKFCOI_00552	7.37e-224	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
KGFKFCOI_00553	5.47e-144	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
KGFKFCOI_00554	5.13e-292	dgoD	4.2.1.6	-	M	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
KGFKFCOI_00555	3.46e-205	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
KGFKFCOI_00556	2.4e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2243)
KGFKFCOI_00557	3.76e-163	-	-	-	S	ko:K02351	-	ko00000	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
KGFKFCOI_00558	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
KGFKFCOI_00559	3.7e-164	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_00560	1.36e-245	-	-	-	K	-	-	-	DJ-1/PfpI family
KGFKFCOI_00561	5.69e-147	-	-	-	S	-	-	-	Predicted membrane protein (DUF2306)
KGFKFCOI_00562	8.84e-266	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
KGFKFCOI_00563	2e-103	-	-	-	S	-	-	-	VanZ like family
KGFKFCOI_00564	1.2e-144	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
KGFKFCOI_00565	3.74e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KGFKFCOI_00566	4.44e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KGFKFCOI_00567	0.0	-	-	-	V	-	-	-	SNF2 family N-terminal domain
KGFKFCOI_00570	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_00571	2.83e-144	-	-	-	-	-	-	-	-
KGFKFCOI_00572	3.59e-147	-	-	-	-	-	-	-	-
KGFKFCOI_00574	2.72e-194	-	-	-	-	-	-	-	-
KGFKFCOI_00575	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
KGFKFCOI_00576	8.92e-29	-	-	-	-	-	-	-	-
KGFKFCOI_00577	3.53e-296	bbsF_2	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
KGFKFCOI_00578	3.56e-152	-	-	-	K	-	-	-	FCD domain
KGFKFCOI_00579	1.62e-212	-	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
KGFKFCOI_00580	2.4e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
KGFKFCOI_00581	8.83e-285	hmrA	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
KGFKFCOI_00582	6.67e-202	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KGFKFCOI_00583	3.91e-145	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
KGFKFCOI_00584	1.78e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGFKFCOI_00585	2.97e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGFKFCOI_00587	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
KGFKFCOI_00588	0.0	aguA	3.2.1.139	-	G	ko:K01235	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 67 family
KGFKFCOI_00589	5.62e-226	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00590	8.06e-199	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
KGFKFCOI_00591	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00592	5.6e-159	-	-	-	S	-	-	-	Protein of unknown function, DUF624
KGFKFCOI_00593	2.81e-257	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
KGFKFCOI_00594	1.84e-49	-	-	-	D	-	-	-	nuclear chromosome segregation
KGFKFCOI_00596	4.52e-283	hutI	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
KGFKFCOI_00597	3.2e-265	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
KGFKFCOI_00598	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_00599	4.39e-219	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00600	3.26e-197	-	-	-	EP	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00601	1.36e-242	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00602	1.5e-242	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00603	4.12e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
KGFKFCOI_00604	5.79e-309	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
KGFKFCOI_00605	1.97e-176	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_00606	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
KGFKFCOI_00607	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
KGFKFCOI_00608	3.69e-259	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
KGFKFCOI_00609	3.43e-281	xylR5	-	-	GK	-	-	-	ROK family
KGFKFCOI_00610	5.09e-161	-	-	-	S	ko:K09992	-	ko00000	Trehalose utilisation
KGFKFCOI_00611	7.54e-285	yrbE	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_00612	0.0	-	-	-	KT	ko:K09684	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
KGFKFCOI_00613	1.6e-143	-	-	-	E	-	-	-	Asp/Glu/Hydantoin racemase
KGFKFCOI_00614	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
KGFKFCOI_00615	7.03e-246	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
KGFKFCOI_00616	8.9e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
KGFKFCOI_00617	7.15e-148	-	-	-	E	ko:K14591	-	ko00000	AroM protein
KGFKFCOI_00618	1.44e-226	-	-	-	E	-	-	-	Thermophilic metalloprotease (M29)
KGFKFCOI_00619	1.22e-285	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
KGFKFCOI_00620	2.4e-42	-	5.3.2.6	-	S	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
KGFKFCOI_00621	5.22e-276	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	chromate transporter, chromate ion transporter
KGFKFCOI_00623	1.2e-59	M1-594	-	-	S	-	-	-	Thiamine-binding protein
KGFKFCOI_00624	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGFKFCOI_00625	1.19e-314	-	-	-	-	-	-	-	-
KGFKFCOI_00627	5.07e-299	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
KGFKFCOI_00628	2.98e-216	-	2.7.1.196, 2.7.1.205	-	K	ko:K02760,ko:K20480	ko00500,ko02024,ko02060,map00500,map02024,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	sequence-specific DNA binding
KGFKFCOI_00629	6.94e-160	yflK	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_00630	4.12e-104	-	-	-	-	-	-	-	-
KGFKFCOI_00631	4.28e-09	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
KGFKFCOI_00632	6.32e-122	ssuE	1.5.1.38, 1.5.1.45	-	S	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
KGFKFCOI_00633	2.7e-232	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_00634	3.35e-270	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
KGFKFCOI_00635	3.67e-178	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KGFKFCOI_00636	1.01e-171	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KGFKFCOI_00637	3.52e-124	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KGFKFCOI_00638	1.86e-210	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
KGFKFCOI_00639	9.04e-159	kdgR	-	-	K	-	-	-	FCD
KGFKFCOI_00640	3.2e-287	-	1.1.1.18, 1.1.1.369, 1.1.1.371	-	S	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_00641	1.24e-46	-	-	-	S	-	-	-	oxidoreductase
KGFKFCOI_00642	3.2e-187	-	-	-	S	-	-	-	oxidoreductase
KGFKFCOI_00643	4.35e-238	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_00644	1.58e-100	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_00645	4.7e-271	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
KGFKFCOI_00646	9.48e-183	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
KGFKFCOI_00647	2.13e-279	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
KGFKFCOI_00648	3.56e-239	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
KGFKFCOI_00649	1.03e-144	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
KGFKFCOI_00650	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
KGFKFCOI_00651	1.19e-185	cbiX	4.99.1.3	-	C	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	CbiX
KGFKFCOI_00652	2.22e-143	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
KGFKFCOI_00653	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KGFKFCOI_00654	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KGFKFCOI_00655	2.18e-22	-	-	-	-	-	-	-	-
KGFKFCOI_00656	1.25e-204	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_00657	1.47e-79	-	-	-	K	-	-	-	GntR family transcriptional regulator
KGFKFCOI_00658	1.63e-280	yraM	-	-	S	-	-	-	PrpF protein
KGFKFCOI_00659	9.21e-89	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
KGFKFCOI_00660	0.0	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_00661	2.11e-271	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_00662	3.92e-215	yraN	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_00663	5.66e-256	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
KGFKFCOI_00664	0.0	-	-	-	C	ko:K13796	-	ko00000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
KGFKFCOI_00665	1.28e-249	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
KGFKFCOI_00666	1.13e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
KGFKFCOI_00667	4.34e-199	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_00668	1.86e-134	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KGFKFCOI_00669	2.38e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_00670	2.28e-242	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
KGFKFCOI_00671	5.3e-215	-	-	-	P	-	-	-	Arsenic resistance protein
KGFKFCOI_00672	1.88e-125	-	-	-	-	-	-	-	-
KGFKFCOI_00673	9.43e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KGFKFCOI_00674	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
KGFKFCOI_00675	1.21e-59	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00676	1.82e-71	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00677	2.9e-310	ywbA	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGFKFCOI_00678	0.0	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGFKFCOI_00679	1.24e-179	celCD	2.7.1.196, 2.7.1.205, 3.5.1.105	-	G	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
KGFKFCOI_00680	6.12e-179	ybgA	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
KGFKFCOI_00681	0.0	chiA	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycoside Hydrolase Family 18
KGFKFCOI_00682	1.2e-65	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
KGFKFCOI_00683	3.01e-73	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KGFKFCOI_00684	1.13e-290	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_00685	1.03e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KGFKFCOI_00686	0.0	kynU	3.7.1.3	-	E	ko:K01556	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
KGFKFCOI_00687	3.44e-153	kynB	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KGFKFCOI_00688	6.18e-206	kynA	1.13.11.11	-	E	ko:K00453	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
KGFKFCOI_00689	2.93e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
KGFKFCOI_00690	2.87e-269	-	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
KGFKFCOI_00692	3.9e-286	gerAC1	-	-	S	ko:K06297	-	ko00000	spore germination
KGFKFCOI_00693	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
KGFKFCOI_00694	5e-174	-	-	-	K	-	-	-	DeoR C terminal sensor domain
KGFKFCOI_00695	8.5e-303	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
KGFKFCOI_00696	3.07e-240	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
KGFKFCOI_00697	1.98e-285	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
KGFKFCOI_00698	6.65e-196	araQ5	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
KGFKFCOI_00699	3.08e-213	cebF	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
KGFKFCOI_00700	4.06e-293	lacE3	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
KGFKFCOI_00702	1.61e-293	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
KGFKFCOI_00703	3.14e-167	-	-	-	T	-	-	-	Response regulator receiver domain
KGFKFCOI_00704	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
KGFKFCOI_00705	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
KGFKFCOI_00706	7.48e-162	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KGFKFCOI_00707	2.78e-251	-	-	-	G	-	-	-	Acyltransferase family
KGFKFCOI_00708	4.88e-208	-	-	-	P	-	-	-	YhfZ C-terminal domain
KGFKFCOI_00709	9.89e-76	-	-	-	S	-	-	-	PRD domain
KGFKFCOI_00710	1.98e-76	-	-	-	S	-	-	-	Protein of unknown function DUF2620
KGFKFCOI_00711	3.44e-283	-	-	-	S	-	-	-	Protein of unknown function
KGFKFCOI_00712	6.07e-223	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
KGFKFCOI_00713	3.72e-262	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
KGFKFCOI_00714	3.3e-281	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
KGFKFCOI_00715	8.26e-292	-	-	-	G	-	-	-	Metalloenzyme superfamily
KGFKFCOI_00717	0.0	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
KGFKFCOI_00718	0.0	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Hsp70 protein
KGFKFCOI_00719	4.65e-182	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_00720	2.79e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
KGFKFCOI_00721	3.54e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KGFKFCOI_00722	6.07e-223	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00723	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00724	9.01e-198	M1-465	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00725	3.86e-204	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00726	3.62e-65	esxA	-	-	S	-	-	-	Belongs to the WXG100 family
KGFKFCOI_00727	7.61e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
KGFKFCOI_00728	1.88e-278	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
KGFKFCOI_00729	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KGFKFCOI_00730	0.0	yueB	-	-	S	-	-	-	domain protein
KGFKFCOI_00731	1.77e-93	-	-	-	S	-	-	-	Family of unknown function (DUF5383)
KGFKFCOI_00732	3.61e-61	-	-	-	-	-	-	-	-
KGFKFCOI_00733	1.71e-65	-	-	-	-	-	-	-	-
KGFKFCOI_00734	4.66e-105	-	-	-	-	-	-	-	-
KGFKFCOI_00735	0.0	-	-	-	S	-	-	-	nuclease activity
KGFKFCOI_00737	6.99e-115	-	-	-	-	-	-	-	-
KGFKFCOI_00741	3.24e-223	-	-	-	G	-	-	-	Glycoside hydrolase family 16
KGFKFCOI_00747	1.01e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
KGFKFCOI_00748	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KGFKFCOI_00749	5.98e-116	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KGFKFCOI_00750	1.7e-106	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_00751	3.12e-181	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGFKFCOI_00752	8.63e-154	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KGFKFCOI_00753	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_00754	3.29e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KGFKFCOI_00755	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGFKFCOI_00756	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
KGFKFCOI_00757	4.77e-151	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
KGFKFCOI_00758	6.63e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
KGFKFCOI_00759	3.55e-109	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	phosphoenolpyruvate-protein phosphotransferase activity
KGFKFCOI_00760	6.61e-256	nreB	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KGFKFCOI_00761	8.71e-148	nreC	-	-	T	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFKFCOI_00762	0.0	narK	-	-	P	ko:K02575,ko:K10850	ko00910,ko02020,map00910,map02020	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
KGFKFCOI_00763	2.12e-167	-	-	-	S	-	-	-	YwiC-like protein
KGFKFCOI_00764	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_00765	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_00766	6.3e-292	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
KGFKFCOI_00767	9.97e-221	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00768	7.53e-206	ytcP1	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00769	1.14e-52	-	-	-	-	-	-	-	-
KGFKFCOI_00770	7.3e-131	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
KGFKFCOI_00771	4.54e-144	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
KGFKFCOI_00772	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
KGFKFCOI_00773	8.93e-219	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_00774	7.66e-251	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
KGFKFCOI_00775	1.93e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_00776	2.08e-138	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFKFCOI_00777	3.13e-282	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
KGFKFCOI_00778	2.16e-99	-	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
KGFKFCOI_00779	2.33e-74	-	-	-	-	-	-	-	-
KGFKFCOI_00780	5.33e-119	-	3.1.1.29	-	K	ko:K01056	-	ko00000,ko01000,ko03012	-acetyltransferase
KGFKFCOI_00781	1.18e-311	-	-	-	EK	-	-	-	Alanine-glyoxylate amino-transferase
KGFKFCOI_00782	1.16e-107	yvbK	-	-	K	-	-	-	acetyltransferase
KGFKFCOI_00783	4.17e-188	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
KGFKFCOI_00784	4.21e-105	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KGFKFCOI_00785	2.09e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KGFKFCOI_00786	1.15e-258	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Sugar diacid utilization regulator
KGFKFCOI_00787	1.18e-252	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
KGFKFCOI_00788	1.11e-166	-	-	-	-	-	-	-	-
KGFKFCOI_00789	3.31e-150	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGFKFCOI_00790	1.25e-241	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KGFKFCOI_00791	2.25e-200	hisJ3	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
KGFKFCOI_00792	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KGFKFCOI_00793	3.7e-123	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
KGFKFCOI_00794	4.31e-166	-	-	-	-	ko:K06336	-	ko00000,ko01002	-
KGFKFCOI_00795	2.82e-127	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
KGFKFCOI_00796	1.35e-169	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KGFKFCOI_00797	1.8e-226	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
KGFKFCOI_00798	2.37e-181	-	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KGFKFCOI_00799	6.83e-224	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
KGFKFCOI_00800	3.03e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KGFKFCOI_00802	2.91e-256	aprE	3.4.21.62	-	O	ko:K01342	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KGFKFCOI_00803	1.91e-299	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
KGFKFCOI_00804	2.26e-147	cwlK	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
KGFKFCOI_00805	0.0	-	-	-	E	ko:K03294,ko:K14052	-	ko00000,ko02000	Amino acid permease
KGFKFCOI_00806	5.77e-210	sseA	2.8.1.1, 2.8.1.2	-	P	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	ko00000,ko00001,ko01000	sulfurtransferase
KGFKFCOI_00807	8.4e-297	yukF	-	-	QT	-	-	-	Transcriptional regulator
KGFKFCOI_00808	3.15e-257	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
KGFKFCOI_00809	2.91e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
KGFKFCOI_00810	2.05e-203	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
KGFKFCOI_00811	3.02e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
KGFKFCOI_00812	5.66e-191	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KGFKFCOI_00813	4.65e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_00814	8.58e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_00815	2.15e-203	-	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
KGFKFCOI_00816	2.52e-301	-	2.7.13.3	-	T	ko:K07706,ko:K07717	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase-like ATPases
KGFKFCOI_00817	5.06e-194	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
KGFKFCOI_00818	6.94e-209	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00819	1e-220	dppC	-	-	EP	ko:K16201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_00820	1.15e-235	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00821	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_00822	1.56e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
KGFKFCOI_00823	4.11e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KGFKFCOI_00824	2.73e-239	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_00825	4.14e-79	hxlR	-	-	K	-	-	-	transcriptional
KGFKFCOI_00826	5.35e-145	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
KGFKFCOI_00827	6.16e-168	-	-	-	T	-	-	-	Universal stress protein family
KGFKFCOI_00828	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KGFKFCOI_00829	5.88e-89	mnhB2	-	-	P	ko:K05566	-	ko00000,ko02000	antiporter activity
KGFKFCOI_00830	1.85e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_00831	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_00832	2.82e-111	mnhE2	-	-	P	ko:K05569	-	ko00000,ko02000	Na+/H+ ion antiporter subunit
KGFKFCOI_00833	2.23e-51	mnhF2	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_00834	7.98e-80	-	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
KGFKFCOI_00835	6.23e-209	-	-	-	S	-	-	-	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KGFKFCOI_00836	4.4e-249	-	-	-	G	-	-	-	Xylose isomerase
KGFKFCOI_00837	3.24e-249	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_00838	1.76e-181	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_00839	3.7e-281	-	-	-	S	ko:K09927	-	ko00000	Winged helix DNA-binding domain
KGFKFCOI_00840	3.3e-145	-	-	-	S	-	-	-	Integral membrane protein
KGFKFCOI_00841	5.02e-63	-	-	-	-	-	-	-	-
KGFKFCOI_00842	2.71e-182	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KGFKFCOI_00843	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
KGFKFCOI_00844	8.21e-132	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KGFKFCOI_00845	7.1e-175	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
KGFKFCOI_00846	1.69e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KGFKFCOI_00847	3.58e-239	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
KGFKFCOI_00848	4.12e-294	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGFKFCOI_00849	4.38e-35	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KGFKFCOI_00850	1.53e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
KGFKFCOI_00851	1.32e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
KGFKFCOI_00852	2.69e-70	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
KGFKFCOI_00853	1.49e-97	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KGFKFCOI_00854	1.25e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
KGFKFCOI_00855	8.36e-72	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
KGFKFCOI_00856	2.89e-110	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KGFKFCOI_00857	1.49e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_00858	7.84e-152	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
KGFKFCOI_00859	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
KGFKFCOI_00860	9.84e-13	-	-	-	-	-	-	-	-
KGFKFCOI_00861	1.4e-114	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KGFKFCOI_00869	1.58e-153	-	-	-	L	-	-	-	ApaLI-like restriction endonuclease
KGFKFCOI_00870	2.04e-295	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
KGFKFCOI_00872	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
KGFKFCOI_00873	7.41e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
KGFKFCOI_00874	2.06e-12	-	-	-	KQ	-	-	-	Methyltransferase
KGFKFCOI_00877	2.53e-127	yrkC	-	-	G	-	-	-	Cupin domain
KGFKFCOI_00878	6.19e-105	-	-	-	L	-	-	-	NUDIX domain
KGFKFCOI_00879	7.16e-114	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
KGFKFCOI_00880	3.27e-185	-	-	-	S	-	-	-	TraX protein
KGFKFCOI_00881	9.73e-226	mviM3	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_00882	7.28e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
KGFKFCOI_00883	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
KGFKFCOI_00884	2.44e-69	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
KGFKFCOI_00885	1.59e-87	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGFKFCOI_00886	2.25e-76	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
KGFKFCOI_00887	1.02e-296	ydfA	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KGFKFCOI_00888	8.4e-102	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KGFKFCOI_00890	4.15e-304	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
KGFKFCOI_00892	6.53e-217	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
KGFKFCOI_00893	9.03e-153	ydhC	-	-	K	-	-	-	FCD
KGFKFCOI_00894	8.34e-255	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
KGFKFCOI_00895	2.4e-86	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGFKFCOI_00896	2.49e-259	-	-	-	K	-	-	-	ArsR family transcriptional regulator
KGFKFCOI_00897	5.32e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KGFKFCOI_00898	1.06e-167	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
KGFKFCOI_00899	0.0	-	-	-	L	-	-	-	ABC transporter
KGFKFCOI_00900	1.32e-97	-	-	-	K	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
KGFKFCOI_00901	5.22e-75	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KGFKFCOI_00903	1.86e-90	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
KGFKFCOI_00904	9.83e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
KGFKFCOI_00905	1.67e-161	azlC	-	-	E	-	-	-	AzlC protein
KGFKFCOI_00906	3.25e-97	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_00907	2.77e-94	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
KGFKFCOI_00908	1.04e-307	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
KGFKFCOI_00909	1.55e-91	-	-	-	J	-	-	-	L-PSP family endoribonuclease
KGFKFCOI_00910	2e-206	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
KGFKFCOI_00911	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
KGFKFCOI_00912	6.44e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
KGFKFCOI_00913	0.0	-	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KGFKFCOI_00914	1.08e-214	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
KGFKFCOI_00915	1.54e-128	-	-	-	-	-	-	-	-
KGFKFCOI_00917	2.57e-36	-	-	-	-	-	-	-	-
KGFKFCOI_00926	8.89e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
KGFKFCOI_00927	2.93e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGFKFCOI_00928	1.93e-77	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGFKFCOI_00929	1.28e-274	-	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KGFKFCOI_00932	4.71e-239	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KGFKFCOI_00933	1.15e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
KGFKFCOI_00934	1.44e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
KGFKFCOI_00935	2.21e-114	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KGFKFCOI_00936	4.31e-233	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KGFKFCOI_00937	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
KGFKFCOI_00938	6.15e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KGFKFCOI_00939	7.3e-34	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KGFKFCOI_00940	2.86e-179	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KGFKFCOI_00941	2.61e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGFKFCOI_00942	4.77e-144	metP_2	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
KGFKFCOI_00943	1.57e-194	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
KGFKFCOI_00944	3.46e-265	gldA	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
KGFKFCOI_00946	2.84e-154	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KGFKFCOI_00947	7.46e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KGFKFCOI_00948	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KGFKFCOI_00949	0.0	-	-	-	G	-	-	-	Mga helix-turn-helix domain
KGFKFCOI_00950	2.88e-96	-	2.7.1.194	-	GT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGFKFCOI_00951	5.5e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
KGFKFCOI_00952	3.06e-283	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
KGFKFCOI_00953	3.13e-170	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
KGFKFCOI_00954	1.75e-158	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KGFKFCOI_00955	1.64e-196	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGFKFCOI_00956	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
KGFKFCOI_00957	6.25e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KGFKFCOI_00958	2.88e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KGFKFCOI_00959	8.27e-111	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
KGFKFCOI_00960	1.3e-240	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KGFKFCOI_00961	4.1e-310	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
KGFKFCOI_00962	4.56e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
KGFKFCOI_00963	2.79e-97	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
KGFKFCOI_00964	4.25e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KGFKFCOI_00965	9.61e-187	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
KGFKFCOI_00966	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
KGFKFCOI_00967	7.47e-141	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
KGFKFCOI_00968	2.48e-177	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KGFKFCOI_00969	9.17e-116	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KGFKFCOI_00970	4.31e-11	-	-	-	-	-	-	-	-
KGFKFCOI_00971	6.31e-11	-	-	-	-	-	-	-	-
KGFKFCOI_00972	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KGFKFCOI_00973	2.15e-92	-	-	-	S	-	-	-	GtrA-like protein
KGFKFCOI_00974	2.7e-232	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
KGFKFCOI_00975	1.89e-197	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KGFKFCOI_00976	7.65e-187	-	-	-	-	-	-	-	-
KGFKFCOI_00977	1.62e-192	tcyA_1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KGFKFCOI_00978	3.11e-145	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00979	8e-154	-	-	-	E	ko:K02029,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_00980	2.4e-192	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
KGFKFCOI_00981	1.06e-96	-	-	-	M	-	-	-	ArpU family transcriptional regulator
KGFKFCOI_00982	0.0	malK	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
KGFKFCOI_00983	3.52e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
KGFKFCOI_00984	2.31e-313	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
KGFKFCOI_00985	4.48e-273	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
KGFKFCOI_00986	5.46e-195	-	-	-	S	-	-	-	Short C-terminal domain
KGFKFCOI_00987	2.21e-94	-	-	-	-	-	-	-	-
KGFKFCOI_00988	1.42e-101	-	-	-	-	-	-	-	-
KGFKFCOI_00989	1.4e-244	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
KGFKFCOI_00990	8.4e-176	-	-	-	S	-	-	-	Phage tail protein
KGFKFCOI_00991	0.0	-	-	-	L	-	-	-	Phage minor structural protein
KGFKFCOI_00993	2.31e-100	-	-	-	S	-	-	-	Bacteriophage holin family
KGFKFCOI_00994	7.89e-153	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
KGFKFCOI_00995	5.56e-139	yfhC	-	-	C	-	-	-	nitroreductase
KGFKFCOI_00996	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
KGFKFCOI_00997	1.15e-12	-	-	-	-	-	-	-	-
KGFKFCOI_00999	1.07e-236	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
KGFKFCOI_01000	3.01e-131	-	-	-	CO	-	-	-	Thioredoxin
KGFKFCOI_01001	1.87e-221	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
KGFKFCOI_01002	3.29e-279	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KGFKFCOI_01003	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
KGFKFCOI_01004	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KGFKFCOI_01005	1.01e-100	-	-	-	S	-	-	-	glyoxalase bleomycin resistance protein dioxygenase
KGFKFCOI_01006	1.4e-314	-	-	-	C	-	-	-	Na+/H+ antiporter family
KGFKFCOI_01007	8.48e-241	dapB	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
KGFKFCOI_01008	5.8e-219	-	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_01009	1.8e-276	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
KGFKFCOI_01010	2.12e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_01011	8.02e-152	XK27_07680	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGFKFCOI_01012	5.04e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KGFKFCOI_01013	0.0	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
KGFKFCOI_01014	2.17e-57	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGFKFCOI_01015	3.16e-296	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
KGFKFCOI_01016	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KGFKFCOI_01017	1.31e-266	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGFKFCOI_01018	3.85e-98	rmaD	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
KGFKFCOI_01019	5.64e-114	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
KGFKFCOI_01020	6.09e-228	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
KGFKFCOI_01021	4.71e-142	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
KGFKFCOI_01022	7.13e-87	-	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
KGFKFCOI_01023	5.14e-34	-	-	-	S	-	-	-	YfhD-like protein
KGFKFCOI_01024	5.25e-279	-	-	-	G	-	-	-	Transmembrane secretion effector
KGFKFCOI_01025	6.13e-232	-	-	-	S	-	-	-	Phosphotransferase enzyme family
KGFKFCOI_01026	3.99e-92	-	-	-	-	-	-	-	-
KGFKFCOI_01027	5.11e-286	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KGFKFCOI_01029	0.0	-	-	-	S	-	-	-	proteins of the AP superfamily
KGFKFCOI_01030	3.6e-112	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGFKFCOI_01031	5.6e-205	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
KGFKFCOI_01032	1.09e-220	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
KGFKFCOI_01033	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
KGFKFCOI_01034	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
KGFKFCOI_01036	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KGFKFCOI_01037	5.49e-38	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_01038	2.93e-102	ygaO	-	-	-	-	-	-	-
KGFKFCOI_01039	1.89e-134	-	-	-	Q	-	-	-	Isochorismatase family
KGFKFCOI_01040	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
KGFKFCOI_01041	0.0	abgT_2	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
KGFKFCOI_01042	8.97e-294	cypA	-	-	C	ko:K15468	-	ko00000,ko01008	Cytochrome P450
KGFKFCOI_01043	2.91e-27	-	-	-	-	-	-	-	-
KGFKFCOI_01044	0.0	-	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KGFKFCOI_01045	2.93e-176	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KGFKFCOI_01046	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KGFKFCOI_01047	3.55e-163	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KGFKFCOI_01048	1.36e-177	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
KGFKFCOI_01049	7.06e-291	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
KGFKFCOI_01050	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KGFKFCOI_01051	3.79e-131	-	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
KGFKFCOI_01052	1.03e-202	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
KGFKFCOI_01053	4.39e-215	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
KGFKFCOI_01054	0.0	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KGFKFCOI_01055	1.93e-137	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
KGFKFCOI_01056	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
KGFKFCOI_01057	0.0	lipA1	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KGFKFCOI_01058	3.5e-147	mqnB	3.2.2.26	-	F	ko:K11783	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KGFKFCOI_01059	2.01e-206	mqnD	-	-	S	ko:K11785	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KGFKFCOI_01060	2.35e-138	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
KGFKFCOI_01061	5.61e-115	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
KGFKFCOI_01062	7.11e-174	-	-	-	K	-	-	-	DeoR C terminal sensor domain
KGFKFCOI_01063	5.41e-173	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01064	2.44e-207	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KGFKFCOI_01065	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
KGFKFCOI_01066	3.46e-155	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_01067	2.48e-174	mta	-	-	K	-	-	-	transcriptional
KGFKFCOI_01068	1.87e-270	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
KGFKFCOI_01069	3.39e-127	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
KGFKFCOI_01072	3.86e-299	-	-	-	G	-	-	-	Major facilitator Superfamily
KGFKFCOI_01074	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_01075	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_01077	3.33e-190	-	-	-	-	-	-	-	-
KGFKFCOI_01078	4.34e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
KGFKFCOI_01079	7.8e-181	-	-	-	-	-	-	-	-
KGFKFCOI_01080	6.9e-27	-	-	-	S	-	-	-	YvrJ protein family
KGFKFCOI_01081	3.74e-142	fliA	-	-	K	ko:K02405,ko:K03093	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	sigma factor activity
KGFKFCOI_01083	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
KGFKFCOI_01084	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
KGFKFCOI_01085	9.4e-156	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KGFKFCOI_01086	1.72e-244	-	-	-	S	ko:K07795	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_01087	7.2e-98	-	-	-	S	ko:K07794	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctB family
KGFKFCOI_01088	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_01089	1.84e-07	-	-	-	T	-	-	-	SpoVT / AbrB like domain
KGFKFCOI_01090	1.54e-92	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
KGFKFCOI_01091	5.03e-43	yebG	-	-	S	-	-	-	NETI protein
KGFKFCOI_01092	8.23e-89	-	-	-	S	-	-	-	Calcium/calmodulin dependent protein kinase II association domain
KGFKFCOI_01093	1.08e-146	-	-	-	-	-	-	-	-
KGFKFCOI_01094	4.2e-157	-	-	-	S	-	-	-	PFAM AIG2 family protein
KGFKFCOI_01095	1.62e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_01096	5.38e-166	-	-	-	S	-	-	-	CAAX protease self-immunity
KGFKFCOI_01097	3.35e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KGFKFCOI_01098	2.02e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KGFKFCOI_01099	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KGFKFCOI_01100	1.96e-165	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KGFKFCOI_01101	5.87e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGFKFCOI_01102	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGFKFCOI_01103	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGFKFCOI_01104	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KGFKFCOI_01105	2.48e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KGFKFCOI_01106	1.03e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KGFKFCOI_01107	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KGFKFCOI_01108	6.49e-304	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KGFKFCOI_01109	2.95e-262	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KGFKFCOI_01110	7.85e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KGFKFCOI_01111	1.35e-177	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01112	5.64e-255	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
KGFKFCOI_01113	1.45e-296	gntT	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
KGFKFCOI_01114	5.63e-176	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01115	1.41e-196	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KGFKFCOI_01116	3.32e-119	ttr	-	-	K	-	-	-	GCN5 family acetyltransferase
KGFKFCOI_01117	4.28e-256	-	-	-	T	-	-	-	Signal transduction histidine kinase
KGFKFCOI_01118	3.54e-140	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
KGFKFCOI_01119	4.96e-219	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_01120	2.73e-282	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
KGFKFCOI_01121	2.72e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
KGFKFCOI_01123	4.09e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
KGFKFCOI_01124	2.83e-53	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
KGFKFCOI_01125	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_01126	1.06e-109	-	-	-	-	-	-	-	-
KGFKFCOI_01127	3.2e-123	-	-	-	-	-	-	-	-
KGFKFCOI_01128	1.91e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01129	6.21e-105	-	-	-	-	-	-	-	-
KGFKFCOI_01130	3.14e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01131	2.64e-86	-	-	-	-	-	-	-	-
KGFKFCOI_01132	1.03e-76	-	-	-	-	-	-	-	-
KGFKFCOI_01133	9.57e-84	-	-	-	U	-	-	-	domain, Protein
KGFKFCOI_01134	6.08e-106	-	-	-	-	-	-	-	-
KGFKFCOI_01135	5.29e-113	-	-	-	-	-	-	-	-
KGFKFCOI_01136	6.18e-67	-	-	-	-	-	-	-	-
KGFKFCOI_01137	5.66e-106	-	-	-	M	-	-	-	nuclease activity
KGFKFCOI_01138	2.12e-106	-	-	-	-	-	-	-	-
KGFKFCOI_01139	3.67e-89	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
KGFKFCOI_01140	4.39e-62	-	-	-	-	-	-	-	-
KGFKFCOI_01141	4.73e-27	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	Belongs to the WXG100 family
KGFKFCOI_01142	7.04e-79	-	-	-	-	-	-	-	-
KGFKFCOI_01143	7.84e-71	-	-	-	-	-	-	-	-
KGFKFCOI_01147	2.13e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
KGFKFCOI_01148	7.21e-281	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
KGFKFCOI_01149	6.84e-190	gbuB	-	-	P	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
KGFKFCOI_01150	1.26e-217	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
KGFKFCOI_01152	2.3e-256	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
KGFKFCOI_01153	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
KGFKFCOI_01154	1.55e-66	yerC	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_01155	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KGFKFCOI_01156	3.8e-314	acyII	3.5.1.11	-	S	ko:K01434	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000,ko01002	Penicillin amidase
KGFKFCOI_01157	1.03e-74	acyII	3.5.1.11	-	S	ko:K01434	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000,ko01002	Penicillin amidase
KGFKFCOI_01158	7.93e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KGFKFCOI_01159	5.02e-33	mepA	-	-	V	-	-	-	MATE efflux family protein
KGFKFCOI_01161	2.09e-227	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_01162	1.16e-222	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_01163	4.33e-196	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KGFKFCOI_01164	1.16e-167	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KGFKFCOI_01165	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KGFKFCOI_01166	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KGFKFCOI_01167	3.07e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
KGFKFCOI_01168	2.24e-261	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
KGFKFCOI_01169	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_01170	1.3e-242	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGFKFCOI_01171	2.6e-209	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGFKFCOI_01173	4.31e-231	-	-	-	-	-	-	-	-
KGFKFCOI_01174	5.2e-118	yizA	-	-	S	-	-	-	DinB family
KGFKFCOI_01175	3.39e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGFKFCOI_01176	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KGFKFCOI_01177	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGFKFCOI_01178	1.43e-219	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KGFKFCOI_01179	1.2e-105	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KGFKFCOI_01180	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGFKFCOI_01181	7.48e-133	-	-	-	-	-	-	-	-
KGFKFCOI_01182	0.0	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
KGFKFCOI_01183	8.46e-58	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
KGFKFCOI_01184	2.22e-284	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
KGFKFCOI_01185	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KGFKFCOI_01186	7.14e-180	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_01187	6.55e-42	-	-	-	K	-	-	-	MerR family transcriptional regulator
KGFKFCOI_01188	2.6e-316	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
KGFKFCOI_01189	0.0	-	4.2.1.82	-	EG	ko:K22396	ko00040,map00040	ko00000,ko00001,ko01000	Dehydratase family
KGFKFCOI_01190	7.44e-184	-	-	-	K	ko:K19333	-	ko00000,ko03000	helix_turn_helix isocitrate lyase regulation
KGFKFCOI_01191	2.75e-211	-	4.2.1.141	-	S	ko:K14259	ko00040,map00040	ko00000,ko00001,ko01000	Fumarylacetoacetate (FAA) hydrolase family
KGFKFCOI_01192	7.32e-215	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
KGFKFCOI_01193	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_01194	3.98e-170	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KGFKFCOI_01195	4.17e-174	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KGFKFCOI_01196	0.0	psaA3	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Zinc-uptake complex component A periplasmic
KGFKFCOI_01197	7.34e-249	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KGFKFCOI_01198	6.68e-237	yjiA	-	-	S	-	-	-	Cobalamin biosynthesis protein CobW
KGFKFCOI_01199	3.48e-210	-	-	-	S	-	-	-	Alpha beta hydrolase
KGFKFCOI_01200	8.44e-178	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
KGFKFCOI_01201	8.57e-216	-	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KGFKFCOI_01202	3.22e-211	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_01203	2.78e-250	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_01204	1.35e-118	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_01205	1.22e-274	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
KGFKFCOI_01206	1.37e-64	-	4.2.1.7	-	G	ko:K16849	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	SAF
KGFKFCOI_01207	4.5e-280	-	4.2.1.7	-	G	ko:K16850	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	D-galactarate dehydratase / Altronate hydrolase, C terminus
KGFKFCOI_01208	0.0	M1-1044	-	-	S	-	-	-	Belongs to the UPF0061 (SELO) family
KGFKFCOI_01209	2.54e-243	nagC_1	-	-	GK	-	-	-	ROK family
KGFKFCOI_01210	1.79e-268	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
KGFKFCOI_01211	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
KGFKFCOI_01212	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_01213	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
KGFKFCOI_01214	6.61e-230	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01215	2.76e-218	lplC1	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01216	0.0	lplA3	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_01217	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
KGFKFCOI_01218	1.82e-170	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
KGFKFCOI_01219	7.25e-144	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_01220	1.19e-259	-	4.2.2.2	-	M	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectic acid lyase
KGFKFCOI_01221	1.78e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_01222	0.0	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_01223	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_01224	1.19e-231	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
KGFKFCOI_01225	5.67e-200	ytcP3	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01226	9.01e-227	-	-	-	E	-	-	-	Abhydrolase family
KGFKFCOI_01227	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
KGFKFCOI_01228	4.85e-284	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KGFKFCOI_01229	4.58e-109	-	-	-	G	-	-	-	carbohydrate transport
KGFKFCOI_01230	3.26e-162	yteU	-	-	S	-	-	-	Integral membrane protein
KGFKFCOI_01231	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_01232	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
KGFKFCOI_01233	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
KGFKFCOI_01234	6.62e-222	-	-	-	K	-	-	-	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KGFKFCOI_01235	1.72e-99	srlR	-	-	K	-	-	-	Glucitol operon activator
KGFKFCOI_01236	5.57e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
KGFKFCOI_01237	4.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
KGFKFCOI_01238	1.5e-76	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KGFKFCOI_01239	7.14e-183	-	1.1.1.140	-	C	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_01240	2.01e-203	-	-	AA10,CBM73	D	ko:K03933	-	ko00000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
KGFKFCOI_01241	8.68e-44	-	-	-	S	-	-	-	Sporulation inhibitor A
KGFKFCOI_01242	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
KGFKFCOI_01243	5.39e-130	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
KGFKFCOI_01244	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
KGFKFCOI_01245	2.97e-303	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
KGFKFCOI_01246	1.68e-227	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KGFKFCOI_01247	6.77e-307	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KGFKFCOI_01248	1.39e-161	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_01249	4.41e-220	ycbM	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_01250	1.73e-219	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_01251	2.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
KGFKFCOI_01252	2.74e-151	ydfE	-	-	S	-	-	-	Flavin reductase like domain
KGFKFCOI_01253	1.82e-160	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KGFKFCOI_01254	2.54e-214	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
KGFKFCOI_01255	2.83e-260	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_01256	1.06e-166	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
KGFKFCOI_01257	1.4e-240	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Arginase family
KGFKFCOI_01258	7.77e-151	-	-	-	S	-	-	-	HTH domain
KGFKFCOI_01259	8.22e-272	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KGFKFCOI_01260	9.33e-226	eutB	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
KGFKFCOI_01261	6.55e-223	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
KGFKFCOI_01262	6.91e-06	-	-	-	S	-	-	-	Sporulation inhibitor A
KGFKFCOI_01263	1.64e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
KGFKFCOI_01264	3.84e-313	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
KGFKFCOI_01265	6.62e-140	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
KGFKFCOI_01266	9.83e-191	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
KGFKFCOI_01267	7.76e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
KGFKFCOI_01268	2.83e-53	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
KGFKFCOI_01269	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_01270	3.55e-79	-	-	-	-	-	-	-	-
KGFKFCOI_01271	3.94e-95	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_01272	5.79e-78	-	-	-	-	-	-	-	-
KGFKFCOI_01273	7.54e-41	-	-	-	T	-	-	-	Protein conserved in bacteria
KGFKFCOI_01274	1.45e-29	-	-	-	-	-	-	-	-
KGFKFCOI_01276	8.24e-82	-	-	-	-	-	-	-	-
KGFKFCOI_01277	7.68e-109	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
KGFKFCOI_01278	7.55e-65	-	-	-	-	-	-	-	-
KGFKFCOI_01279	3.46e-87	-	-	-	-	-	-	-	-
KGFKFCOI_01280	5.09e-19	-	-	-	-	-	-	-	-
KGFKFCOI_01281	1.08e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1569)
KGFKFCOI_01282	7.45e-101	yuxK	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_01283	2.16e-124	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
KGFKFCOI_01284	0.0	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGFKFCOI_01285	6.8e-135	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
KGFKFCOI_01286	1.05e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
KGFKFCOI_01287	3.42e-97	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KGFKFCOI_01288	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
KGFKFCOI_01289	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
KGFKFCOI_01290	4.88e-161	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
KGFKFCOI_01291	1.05e-176	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
KGFKFCOI_01292	3.24e-170	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
KGFKFCOI_01293	1.62e-161	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_01294	2.21e-221	yisR1	3.2.1.23	-	K	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	AraC-like ligand binding domain
KGFKFCOI_01295	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
KGFKFCOI_01296	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_01297	2.72e-222	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01298	7e-196	malG	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01299	6.15e-127	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_01300	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_01301	8.15e-267	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
KGFKFCOI_01302	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_01303	2.25e-207	-	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_01304	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGFKFCOI_01305	1.05e-206	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
KGFKFCOI_01306	0.0	dld	1.1.2.4, 1.1.3.15	-	C	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
KGFKFCOI_01307	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
KGFKFCOI_01308	1.62e-106	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KGFKFCOI_01309	1.61e-251	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
KGFKFCOI_01310	7.52e-176	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
KGFKFCOI_01311	2.72e-172	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
KGFKFCOI_01312	2.8e-256	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KGFKFCOI_01313	2.69e-248	-	-	-	-	-	-	-	-
KGFKFCOI_01314	1.74e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	transport system, ATPase component
KGFKFCOI_01315	1.2e-219	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGFKFCOI_01316	8.97e-227	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	transport system, periplasmic component
KGFKFCOI_01317	4.47e-294	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
KGFKFCOI_01318	1.11e-133	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_01319	2.46e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
KGFKFCOI_01320	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KGFKFCOI_01321	5.69e-235	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_01322	6.99e-242	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_01323	0.0	hbpA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_01324	3.99e-233	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_01325	4.88e-207	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_01326	1.12e-209	pepI	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha/beta hydrolase family
KGFKFCOI_01327	2.01e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_01328	3.55e-313	-	-	-	V	-	-	-	MatE
KGFKFCOI_01329	5.02e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGFKFCOI_01330	3.66e-184	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_01331	1.22e-175	phnE	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_01332	3.79e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KGFKFCOI_01333	5.37e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
KGFKFCOI_01334	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGFKFCOI_01335	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KGFKFCOI_01336	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_01337	2.52e-298	kinB3	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_01338	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KGFKFCOI_01339	0.0	glpD	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KGFKFCOI_01340	2.04e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KGFKFCOI_01341	3.33e-315	alsT	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
KGFKFCOI_01342	1.21e-301	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGFKFCOI_01343	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
KGFKFCOI_01344	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
KGFKFCOI_01345	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_01346	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
KGFKFCOI_01347	9.73e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
KGFKFCOI_01348	1.13e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
KGFKFCOI_01349	1.6e-274	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KGFKFCOI_01350	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KGFKFCOI_01351	2.57e-173	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_01352	1.35e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
KGFKFCOI_01353	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KGFKFCOI_01354	3.04e-233	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
KGFKFCOI_01355	3.95e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KGFKFCOI_01356	2.07e-75	-	-	-	-	-	-	-	-
KGFKFCOI_01357	2.17e-62	-	-	-	K	-	-	-	SpoVT / AbrB like domain
KGFKFCOI_01358	1.81e-54	-	-	-	-	-	-	-	-
KGFKFCOI_01359	4.23e-147	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
KGFKFCOI_01360	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KGFKFCOI_01361	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
KGFKFCOI_01362	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
KGFKFCOI_01363	0.0	kat	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
KGFKFCOI_01364	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
KGFKFCOI_01365	4.3e-187	-	-	-	-	-	-	-	-
KGFKFCOI_01366	5.11e-242	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KGFKFCOI_01367	2.06e-314	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
KGFKFCOI_01368	1.21e-29	-	-	-	S	-	-	-	Fur-regulated basic protein B
KGFKFCOI_01371	4.85e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
KGFKFCOI_01372	4.13e-280	yfkA	-	-	S	-	-	-	YfkB-like domain
KGFKFCOI_01373	1.2e-154	-	-	-	G	ko:K15640	-	ko00000	Belongs to the phosphoglycerate mutase family
KGFKFCOI_01374	0.0	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
KGFKFCOI_01375	7.39e-187	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
KGFKFCOI_01376	1.35e-191	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
KGFKFCOI_01377	4.26e-219	-	-	-	O	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
KGFKFCOI_01378	2.51e-94	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_01380	2.29e-81	-	-	-	-	-	-	-	-
KGFKFCOI_01381	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGFKFCOI_01382	1.51e-263	mccF	-	-	V	-	-	-	LD-carboxypeptidase
KGFKFCOI_01383	4.73e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01384	1.43e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
KGFKFCOI_01385	2.03e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
KGFKFCOI_01386	1.58e-70	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
KGFKFCOI_01387	9.25e-30	-	-	-	S	-	-	-	YpzG-like protein
KGFKFCOI_01389	2.17e-242	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
KGFKFCOI_01390	9.61e-267	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
KGFKFCOI_01391	2.28e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01392	3.86e-78	-	-	-	-	-	-	-	-
KGFKFCOI_01393	5.62e-27	yfhS	-	-	-	-	-	-	-
KGFKFCOI_01394	9.29e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01395	6.03e-23	-	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
KGFKFCOI_01396	2.94e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KGFKFCOI_01397	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
KGFKFCOI_01398	2.34e-242	ygaE	-	-	S	-	-	-	Membrane
KGFKFCOI_01399	4.31e-315	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
KGFKFCOI_01400	4.85e-116	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
KGFKFCOI_01401	2.42e-234	ghrA	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGFKFCOI_01402	6.47e-64	-	-	-	S	-	-	-	Cyclic-di-AMP receptor
KGFKFCOI_01403	1.18e-103	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KGFKFCOI_01404	1.87e-76	ygzB	-	-	S	-	-	-	UPF0295 protein
KGFKFCOI_01421	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
KGFKFCOI_01423	2.81e-231	-	-	-	L	-	-	-	Phage integrase family
KGFKFCOI_01426	1.24e-146	-	-	-	-	-	-	-	-
KGFKFCOI_01428	1.7e-101	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
KGFKFCOI_01430	7.13e-110	-	-	-	L	-	-	-	phage terminase small subunit
KGFKFCOI_01431	0.0	-	-	-	S	-	-	-	Terminase
KGFKFCOI_01432	5.59e-37	-	-	-	-	-	-	-	-
KGFKFCOI_01433	0.0	-	-	-	S	-	-	-	Phage portal protein
KGFKFCOI_01434	5.7e-146	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
KGFKFCOI_01435	6.1e-294	-	-	-	S	-	-	-	capsid protein
KGFKFCOI_01436	5.98e-94	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
KGFKFCOI_01437	3.2e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KGFKFCOI_01438	1.75e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
KGFKFCOI_01439	4.98e-16	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
KGFKFCOI_01440	2.74e-73	-	-	-	-	-	-	-	-
KGFKFCOI_01441	4.21e-144	-	-	-	N	-	-	-	phage major tail protein, phi13 family
KGFKFCOI_01444	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
KGFKFCOI_01445	5.45e-205	-	-	-	S	-	-	-	Phage tail protein
KGFKFCOI_01446	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
KGFKFCOI_01447	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_01452	0.0	-	-	-	L	-	-	-	Prophage endopeptidase tail
KGFKFCOI_01453	4.34e-85	-	-	-	S	-	-	-	Bacteriophage holin family
KGFKFCOI_01454	1.74e-224	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
KGFKFCOI_01455	2.48e-80	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
KGFKFCOI_01458	1.36e-86	yqiX	-	-	S	-	-	-	YolD-like protein
KGFKFCOI_01459	1.64e-35	-	-	-	-	-	-	-	-
KGFKFCOI_01462	4.22e-109	-	-	-	E	-	-	-	Zn peptidase
KGFKFCOI_01463	5.88e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_01464	6.59e-36	-	-	-	-	-	-	-	-
KGFKFCOI_01466	3.77e-68	-	-	-	-	-	-	-	-
KGFKFCOI_01468	5.51e-28	-	-	-	-	-	-	-	-
KGFKFCOI_01469	1.68e-122	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
KGFKFCOI_01470	8.61e-224	-	-	-	D	-	-	-	AAA domain
KGFKFCOI_01471	6.8e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
KGFKFCOI_01472	0.0	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
KGFKFCOI_01473	3.51e-101	-	-	-	-	-	-	-	-
KGFKFCOI_01474	1.91e-125	-	-	-	L	-	-	-	ERCC4 domain
KGFKFCOI_01475	2.57e-59	-	-	-	-	-	-	-	-
KGFKFCOI_01477	3.36e-77	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
KGFKFCOI_01479	5.51e-42	-	-	-	-	-	-	-	-
KGFKFCOI_01481	1.61e-88	-	-	-	S	-	-	-	Phosphoribosyl-ATP pyrophosphohydrolase
KGFKFCOI_01482	8.53e-41	-	-	-	-	-	-	-	-
KGFKFCOI_01483	1.6e-98	-	-	-	S	-	-	-	Transcriptional regulator
KGFKFCOI_01484	3.02e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3533)
KGFKFCOI_01485	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
KGFKFCOI_01486	1.78e-267	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
KGFKFCOI_01487	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
KGFKFCOI_01488	4.08e-88	-	-	-	J	-	-	-	oxidation-reduction process
KGFKFCOI_01489	2.05e-109	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KGFKFCOI_01490	1.85e-220	-	-	-	S	-	-	-	thiolester hydrolase activity
KGFKFCOI_01491	1.32e-300	-	3.3.2.9	-	S	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	ko00000,ko00001,ko01000,ko01002	Epoxide hydrolase N terminus
KGFKFCOI_01492	3.26e-66	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_01493	1.02e-12	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_01494	0.0	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KGFKFCOI_01495	1.12e-142	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
KGFKFCOI_01496	2.35e-101	nsrR3	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_01497	0.0	ypfE	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
KGFKFCOI_01498	3.8e-91	-	-	-	-	-	-	-	-
KGFKFCOI_01499	1.64e-125	-	-	-	F	-	-	-	uridine kinase
KGFKFCOI_01500	3.39e-184	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_01501	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
KGFKFCOI_01502	7.76e-182	-	-	-	M	-	-	-	RIO1 family
KGFKFCOI_01503	9.24e-272	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
KGFKFCOI_01504	0.0	-	-	-	L	-	-	-	AAA ATPase domain
KGFKFCOI_01505	2.29e-76	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
KGFKFCOI_01506	2.97e-51	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
KGFKFCOI_01507	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
KGFKFCOI_01508	4.25e-43	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
KGFKFCOI_01509	1.22e-215	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_01510	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
KGFKFCOI_01511	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
KGFKFCOI_01512	3.04e-278	-	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	amidohydrolase
KGFKFCOI_01513	1.88e-67	-	-	-	S	-	-	-	PRD domain
KGFKFCOI_01514	2.29e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
KGFKFCOI_01515	6.36e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
KGFKFCOI_01516	9.36e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
KGFKFCOI_01517	4.08e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
KGFKFCOI_01518	3.57e-261	selA	2.9.1.1	-	E	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
KGFKFCOI_01519	1.28e-165	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
KGFKFCOI_01521	2.61e-235	pld1	1.1.1.122	-	C	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Aldo/keto reductase family
KGFKFCOI_01522	5.4e-58	-	-	-	H	-	-	-	RibD C-terminal domain
KGFKFCOI_01523	1.19e-77	-	-	-	S	-	-	-	YjbR
KGFKFCOI_01524	5.75e-98	-	-	-	S	-	-	-	Glyoxalase-like domain
KGFKFCOI_01525	4.41e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGFKFCOI_01526	3.69e-124	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KGFKFCOI_01527	5.72e-198	-	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
KGFKFCOI_01528	8.9e-137	-	-	-	K	-	-	-	TetR family transcriptional regulator
KGFKFCOI_01529	1e-271	-	-	-	CH	-	-	-	FAD binding domain
KGFKFCOI_01530	6.28e-276	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KGFKFCOI_01531	4.01e-12	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_01532	8.01e-227	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
KGFKFCOI_01533	1.04e-76	ydzF	-	-	K	-	-	-	HxlR-like helix-turn-helix
KGFKFCOI_01534	1.88e-309	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGFKFCOI_01535	1.14e-167	-	-	-	L	-	-	-	DNA alkylation repair enzyme
KGFKFCOI_01536	7.92e-76	-	-	-	S	-	-	-	AAA domain
KGFKFCOI_01537	5.27e-128	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
KGFKFCOI_01538	9.26e-251	-	-	-	T	-	-	-	Signal transduction histidine kinase
KGFKFCOI_01539	4.49e-143	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
KGFKFCOI_01540	1.54e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_01541	2.79e-293	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGFKFCOI_01542	1.36e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KGFKFCOI_01543	8.79e-200	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
KGFKFCOI_01544	1.34e-91	yxjI	-	-	S	-	-	-	LURP-one-related
KGFKFCOI_01545	9.42e-225	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KGFKFCOI_01546	1.56e-169	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KGFKFCOI_01547	2.51e-130	p20	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_01548	2.2e-62	-	-	-	-	-	-	-	-
KGFKFCOI_01549	2.84e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KGFKFCOI_01550	0.0	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
KGFKFCOI_01551	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K06931,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KGFKFCOI_01552	8.39e-75	-	-	-	S	-	-	-	Regulatory protein YrvL
KGFKFCOI_01553	1.16e-243	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
KGFKFCOI_01554	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
KGFKFCOI_01555	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KGFKFCOI_01556	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
KGFKFCOI_01557	2.45e-124	-	-	-	-	-	-	-	-
KGFKFCOI_01558	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_01559	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_01560	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
KGFKFCOI_01561	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KGFKFCOI_01562	1.1e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KGFKFCOI_01563	1.36e-121	-	-	-	S	-	-	-	MepB protein
KGFKFCOI_01564	2.75e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_01565	2.02e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KGFKFCOI_01566	1.55e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_01567	2.9e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGFKFCOI_01568	8.6e-169	-	-	-	-	-	-	-	-
KGFKFCOI_01569	8.32e-254	yhfE	-	-	G	-	-	-	peptidase M42
KGFKFCOI_01570	6.41e-106	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KGFKFCOI_01571	8e-131	yhzB	-	-	S	-	-	-	B3/4 domain
KGFKFCOI_01572	6.67e-284	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KGFKFCOI_01573	9.84e-123	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KGFKFCOI_01574	4.7e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_01575	1.66e-215	yhbB	-	-	S	-	-	-	Putative amidase domain
KGFKFCOI_01576	1.24e-114	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KGFKFCOI_01577	3.08e-115	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
KGFKFCOI_01578	1.17e-71	-	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
KGFKFCOI_01579	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
KGFKFCOI_01580	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
KGFKFCOI_01581	2.19e-135	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KGFKFCOI_01582	5.91e-180	cysA1	-	-	S	-	-	-	AAA domain
KGFKFCOI_01583	1.11e-281	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
KGFKFCOI_01585	1.07e-213	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_01586	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
KGFKFCOI_01587	1.18e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_01588	3.14e-191	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KGFKFCOI_01590	7.16e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF664)
KGFKFCOI_01591	0.0	-	-	-	G	ko:K10297	-	ko00000,ko04121	Right handed beta helix region
KGFKFCOI_01592	4.72e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_01593	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
KGFKFCOI_01594	3.83e-165	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
KGFKFCOI_01595	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KGFKFCOI_01596	1.97e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
KGFKFCOI_01597	1.94e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KGFKFCOI_01598	6.62e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KGFKFCOI_01599	4e-170	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
KGFKFCOI_01600	2.44e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KGFKFCOI_01601	1.4e-151	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
KGFKFCOI_01602	2.31e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KGFKFCOI_01603	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KGFKFCOI_01604	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KGFKFCOI_01605	7.42e-162	sfsA	-	-	S	ko:K06206	-	ko00000	Sugar fermentation stimulation protein
KGFKFCOI_01606	0.0	-	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
KGFKFCOI_01607	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
KGFKFCOI_01608	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
KGFKFCOI_01609	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_01610	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_01611	1.56e-296	avtA	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGFKFCOI_01612	4.1e-193	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
KGFKFCOI_01613	3.52e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KGFKFCOI_01614	1.97e-275	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
KGFKFCOI_01615	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
KGFKFCOI_01616	1.95e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
KGFKFCOI_01617	1.07e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
KGFKFCOI_01618	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KGFKFCOI_01620	2.14e-278	-	-	-	-	-	-	-	-
KGFKFCOI_01621	1.78e-102	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
KGFKFCOI_01622	8.44e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_01623	1.04e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
KGFKFCOI_01624	2.94e-31	-	-	-	-	-	-	-	-
KGFKFCOI_01626	4.95e-268	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
KGFKFCOI_01627	2.8e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KGFKFCOI_01628	5.03e-202	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
KGFKFCOI_01630	1.47e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01631	2.31e-162	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_01632	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_01633	4.85e-231	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
KGFKFCOI_01634	6.88e-59	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
KGFKFCOI_01635	2.1e-213	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KGFKFCOI_01636	2.48e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
KGFKFCOI_01637	8.43e-141	-	-	-	S	-	-	-	Protein conserved in bacteria
KGFKFCOI_01638	2.03e-141	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
KGFKFCOI_01639	9.77e-73	yhaH	-	-	D	-	-	-	gas vesicle protein
KGFKFCOI_01640	7.59e-269	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KGFKFCOI_01641	1.56e-98	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KGFKFCOI_01642	8.06e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
KGFKFCOI_01643	8.89e-288	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_01644	6.61e-167	ecsC	-	-	S	-	-	-	EcsC protein family
KGFKFCOI_01645	1.59e-156	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
KGFKFCOI_01646	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KGFKFCOI_01647	5.06e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KGFKFCOI_01648	2.06e-233	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KGFKFCOI_01649	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KGFKFCOI_01651	4.46e-132	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
KGFKFCOI_01652	1.51e-296	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KGFKFCOI_01653	3.91e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
KGFKFCOI_01654	1.65e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
KGFKFCOI_01655	4.96e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
KGFKFCOI_01656	8.85e-267	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
KGFKFCOI_01657	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
KGFKFCOI_01658	8.69e-195	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
KGFKFCOI_01659	1.31e-269	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KGFKFCOI_01660	2.93e-275	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
KGFKFCOI_01661	7.43e-25	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGFKFCOI_01662	4.73e-85	-	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	cytochrome c oxidase subunit II
KGFKFCOI_01663	5.29e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
KGFKFCOI_01664	1.41e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KGFKFCOI_01665	2.23e-234	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KGFKFCOI_01666	7.27e-38	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
KGFKFCOI_01667	3.49e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KGFKFCOI_01668	6.48e-291	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KGFKFCOI_01669	1.92e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
KGFKFCOI_01670	3.57e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
KGFKFCOI_01671	1.34e-103	-	-	-	S	-	-	-	membrane
KGFKFCOI_01672	1.13e-44	yodI	-	-	-	-	-	-	-
KGFKFCOI_01673	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGFKFCOI_01674	2.15e-29	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
KGFKFCOI_01675	5.23e-295	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KGFKFCOI_01676	2.54e-197	secF	-	-	U	ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KGFKFCOI_01677	7.21e-53	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
KGFKFCOI_01678	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KGFKFCOI_01679	4.03e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KGFKFCOI_01680	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KGFKFCOI_01681	5.58e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KGFKFCOI_01682	5.96e-240	-	-	-	K	-	-	-	LacI family transcriptional regulator
KGFKFCOI_01683	9.13e-185	thuA	-	-	G	-	-	-	Trehalose utilisation
KGFKFCOI_01684	8.24e-248	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_01685	6.12e-282	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
KGFKFCOI_01687	3.51e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KGFKFCOI_01688	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KGFKFCOI_01689	3.74e-283	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KGFKFCOI_01690	5.89e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01691	2.58e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KGFKFCOI_01692	2.12e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KGFKFCOI_01693	1.34e-139	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_01694	1.7e-298	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KGFKFCOI_01695	2.93e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_01696	5.86e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
KGFKFCOI_01697	2.57e-276	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KGFKFCOI_01698	1.7e-65	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
KGFKFCOI_01699	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KGFKFCOI_01700	1.19e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_01701	1.11e-41	yrzR	-	-	-	-	-	-	-
KGFKFCOI_01702	4.34e-240	yrrI	-	-	S	-	-	-	AI-2E family transporter
KGFKFCOI_01703	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KGFKFCOI_01704	6.53e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KGFKFCOI_01705	2.3e-96	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KGFKFCOI_01706	1.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KGFKFCOI_01707	2.1e-269	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGFKFCOI_01708	1.19e-150	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
KGFKFCOI_01709	6.91e-149	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KGFKFCOI_01710	8.99e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGFKFCOI_01711	2.42e-17	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
KGFKFCOI_01712	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
KGFKFCOI_01713	7.14e-192	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KGFKFCOI_01714	8.69e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KGFKFCOI_01716	7.57e-103	-	-	-	-	-	-	-	-
KGFKFCOI_01717	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KGFKFCOI_01718	7.14e-191	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGFKFCOI_01719	4.46e-185	-	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
KGFKFCOI_01720	3.86e-206	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
KGFKFCOI_01721	2.1e-197	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_01722	7.24e-141	arpR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_01723	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Starch/carbohydrate-binding module (family 53)
KGFKFCOI_01724	7.56e-148	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KGFKFCOI_01725	3.46e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KGFKFCOI_01726	0.0	-	-	-	S	-	-	-	Membrane
KGFKFCOI_01727	2.43e-285	hipO3	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
KGFKFCOI_01728	7.86e-217	ybaS	-	-	S	-	-	-	Na -dependent transporter
KGFKFCOI_01729	1.27e-159	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_01730	2.71e-35	-	-	-	-	-	-	-	-
KGFKFCOI_01732	8.1e-71	-	-	-	-	-	-	-	-
KGFKFCOI_01733	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
KGFKFCOI_01734	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KGFKFCOI_01735	5.47e-76	nirD	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
KGFKFCOI_01736	0.0	nirB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KGFKFCOI_01737	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGFKFCOI_01738	7.82e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
KGFKFCOI_01739	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
KGFKFCOI_01741	3.05e-196	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KGFKFCOI_01742	5.78e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGFKFCOI_01743	1.19e-88	-	-	-	P	ko:K05571	-	ko00000,ko02000	Na+/H+ antiporter subunit
KGFKFCOI_01744	4.41e-52	-	-	-	P	ko:K05570	-	ko00000,ko02000	Multiple resistance and pH regulation protein F (MrpF / PhaF)
KGFKFCOI_01745	1.54e-106	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_01746	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_01747	1.13e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_01748	1.09e-95	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KGFKFCOI_01749	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KGFKFCOI_01751	1.52e-125	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
KGFKFCOI_01752	4.12e-277	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KGFKFCOI_01753	3.71e-197	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KGFKFCOI_01754	2.64e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
KGFKFCOI_01755	5.17e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KGFKFCOI_01756	7.33e-141	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
KGFKFCOI_01757	5.25e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KGFKFCOI_01758	3.61e-209	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
KGFKFCOI_01759	1.4e-182	-	-	-	S	-	-	-	Methyltransferase domain
KGFKFCOI_01760	3.69e-193	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGFKFCOI_01761	1.51e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
KGFKFCOI_01762	8.89e-143	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KGFKFCOI_01763	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KGFKFCOI_01764	9.62e-09	-	-	-	S	-	-	-	YqzM-like protein
KGFKFCOI_01765	2.59e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KGFKFCOI_01766	1.15e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KGFKFCOI_01767	1.25e-262	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KGFKFCOI_01768	5.79e-269	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
KGFKFCOI_01769	2.63e-71	-	-	-	-	-	-	-	-
KGFKFCOI_01770	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KGFKFCOI_01771	4.89e-284	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
KGFKFCOI_01772	7.24e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KGFKFCOI_01773	3.52e-113	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KGFKFCOI_01774	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KGFKFCOI_01775	4.95e-269	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KGFKFCOI_01776	3.65e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
KGFKFCOI_01777	1.09e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KGFKFCOI_01778	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
KGFKFCOI_01779	8.34e-179	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
KGFKFCOI_01780	1.3e-282	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGFKFCOI_01781	7.36e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGFKFCOI_01782	6.08e-225	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
KGFKFCOI_01783	2.92e-206	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
KGFKFCOI_01784	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KGFKFCOI_01785	3.29e-94	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
KGFKFCOI_01786	1.48e-291	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
KGFKFCOI_01787	1.79e-156	yqfA	-	-	S	-	-	-	UPF0365 protein
KGFKFCOI_01788	2.93e-108	-	-	-	-	-	-	-	-
KGFKFCOI_01789	1.73e-63	yqfC	-	-	S	-	-	-	sporulation protein YqfC
KGFKFCOI_01790	4.2e-284	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
KGFKFCOI_01791	1.6e-221	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
KGFKFCOI_01792	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
KGFKFCOI_01793	4.11e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KGFKFCOI_01794	4.46e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KGFKFCOI_01795	2.32e-94	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KGFKFCOI_01796	1.22e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KGFKFCOI_01797	2.53e-25	-	-	-	S	-	-	-	YqzL-like protein
KGFKFCOI_01798	5.46e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KGFKFCOI_01800	1.43e-220	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KGFKFCOI_01801	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KGFKFCOI_01802	1.56e-145	ccpN	-	-	K	-	-	-	CBS domain
KGFKFCOI_01803	1.01e-183	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KGFKFCOI_01804	5.47e-103	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
KGFKFCOI_01805	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KGFKFCOI_01806	1.45e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KGFKFCOI_01807	4.86e-84	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
KGFKFCOI_01808	1.49e-180	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KGFKFCOI_01809	5.88e-257	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KGFKFCOI_01810	9.03e-229	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KGFKFCOI_01811	1.65e-111	-	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
KGFKFCOI_01812	9.84e-106	yqfQ	-	-	S	-	-	-	YqfQ-like protein
KGFKFCOI_01813	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KGFKFCOI_01814	1.31e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KGFKFCOI_01816	2.78e-274	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
KGFKFCOI_01817	9.77e-170	-	-	-	M	-	-	-	Transglycosylase SLT domain
KGFKFCOI_01818	2.06e-185	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KGFKFCOI_01819	9.87e-185	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KGFKFCOI_01820	3.86e-102	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KGFKFCOI_01821	1.79e-50	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
KGFKFCOI_01822	7.94e-145	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
KGFKFCOI_01823	1.19e-88	yqfX	-	-	S	-	-	-	membrane
KGFKFCOI_01824	6.11e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KGFKFCOI_01825	4.71e-80	fimV	-	-	NU	ko:K08086,ko:K15845	ko05120,map05120	ko00000,ko00001	translation initiation factor activity
KGFKFCOI_01826	1.06e-244	-	-	-	EGP	ko:K08221	-	ko00000,ko02000	Sugar (and other) transporter
KGFKFCOI_01827	1.61e-196	ypuA	-	-	S	-	-	-	Secreted protein
KGFKFCOI_01828	6.09e-152	-	-	-	O	-	-	-	NfeD-like C-terminal, partner-binding
KGFKFCOI_01829	2.39e-253	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFKFCOI_01830	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
KGFKFCOI_01836	1.93e-149	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
KGFKFCOI_01837	3.71e-298	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
KGFKFCOI_01838	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
KGFKFCOI_01839	4.28e-102	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGFKFCOI_01840	2.23e-80	-	-	-	-	-	-	-	-
KGFKFCOI_01841	3.15e-162	-	-	-	G	-	-	-	PFAM Glycoside hydrolase 15-related
KGFKFCOI_01842	6.04e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KGFKFCOI_01843	4.98e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KGFKFCOI_01844	2.39e-184	-	-	-	S	-	-	-	Integral membrane protein DUF92
KGFKFCOI_01845	4.38e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KGFKFCOI_01846	1.33e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
KGFKFCOI_01848	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
KGFKFCOI_01849	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Bacillus/Clostridium GerA spore germination protein
KGFKFCOI_01850	8.61e-89	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KGFKFCOI_01851	6.67e-109	-	-	-	-	-	-	-	-
KGFKFCOI_01852	8.32e-12	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_01853	1.24e-232	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KGFKFCOI_01854	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
KGFKFCOI_01855	1.15e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KGFKFCOI_01856	4.45e-38	-	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
KGFKFCOI_01857	7.4e-182	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KGFKFCOI_01858	2.28e-272	thiO	1.4.3.19	-	E	ko:K03153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
KGFKFCOI_01859	1.13e-185	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KGFKFCOI_01860	1.18e-128	-	-	-	-	-	-	-	-
KGFKFCOI_01861	5.01e-251	yqgV	-	-	S	-	-	-	Thiamine-binding protein
KGFKFCOI_01862	1.64e-103	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_01863	1.25e-123	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
KGFKFCOI_01864	5.06e-179	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
KGFKFCOI_01865	4.16e-42	-	-	-	-	-	-	-	-
KGFKFCOI_01866	2.49e-67	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_01867	2.58e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KGFKFCOI_01868	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KGFKFCOI_01869	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KGFKFCOI_01870	3.35e-121	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGFKFCOI_01871	1.33e-229	-	-	-	F	-	-	-	GHKL domain
KGFKFCOI_01872	1.41e-218	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
KGFKFCOI_01873	6.58e-122	yqjB	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_01875	3.72e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
KGFKFCOI_01876	3.28e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
KGFKFCOI_01879	1e-91	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
KGFKFCOI_01880	9.53e-107	-	-	-	S	-	-	-	Pfam Polyketide cyclase dehydrase and lipid transport
KGFKFCOI_01881	7.08e-96	ykuL	-	-	S	-	-	-	CBS domain
KGFKFCOI_01882	1.75e-56	-	-	-	-	-	-	-	-
KGFKFCOI_01883	0.0	apr	-	-	O	-	-	-	Belongs to the peptidase S8 family
KGFKFCOI_01884	9.84e-193	yibQ	-	-	S	ko:K09798	-	ko00000	protein conserved in bacteria
KGFKFCOI_01885	3.57e-62	tnrA	-	-	K	-	-	-	transcriptional
KGFKFCOI_01886	1.53e-66	-	-	-	-	-	-	-	-
KGFKFCOI_01888	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KGFKFCOI_01889	2.33e-167	-	-	-	P	ko:K08714	-	ko00000,ko02000	Polycystin cation channel
KGFKFCOI_01890	1.74e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGFKFCOI_01891	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KGFKFCOI_01892	1.3e-264	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KGFKFCOI_01893	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KGFKFCOI_01894	1.71e-239	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
KGFKFCOI_01895	3.54e-110	-	-	-	V	-	-	-	COG4767 Glycopeptide antibiotics resistance protein
KGFKFCOI_01896	1.08e-71	ogt	-	-	L	ko:K07443	-	ko00000	Methyltransferase
KGFKFCOI_01897	2.49e-128	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
KGFKFCOI_01898	2.45e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
KGFKFCOI_01899	9.24e-122	-	-	-	S	-	-	-	UPF0316 protein
KGFKFCOI_01900	1.73e-270	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KGFKFCOI_01901	2.65e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KGFKFCOI_01902	8.65e-116	-	-	-	CO	-	-	-	Thioredoxin-like
KGFKFCOI_01904	1.1e-121	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
KGFKFCOI_01905	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KGFKFCOI_01906	9.28e-113	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KGFKFCOI_01907	8.77e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
KGFKFCOI_01908	1.87e-217	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
KGFKFCOI_01909	8.89e-290	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGFKFCOI_01910	7.28e-303	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
KGFKFCOI_01911	4.19e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
KGFKFCOI_01912	3.72e-154	-	-	-	J	-	-	-	translation release factor activity
KGFKFCOI_01913	9.25e-306	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
KGFKFCOI_01914	4.52e-29	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
KGFKFCOI_01915	4.46e-74	-	-	-	-	-	-	-	-
KGFKFCOI_01916	2.8e-111	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
KGFKFCOI_01917	3.24e-182	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
KGFKFCOI_01918	2.05e-276	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KGFKFCOI_01919	7.27e-73	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
KGFKFCOI_01920	1.32e-97	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KGFKFCOI_01921	9.34e-176	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_01922	7.14e-105	-	-	-	S	ko:K06405	-	ko00000	Pfam:SpoVA
KGFKFCOI_01923	2.93e-235	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
KGFKFCOI_01924	8.69e-76	-	-	-	S	ko:K06407	-	ko00000	Pfam:SpoVA
KGFKFCOI_01925	5.35e-139	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
KGFKFCOI_01926	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
KGFKFCOI_01927	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KGFKFCOI_01928	4.61e-106	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGFKFCOI_01929	5.1e-207	ccpC	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_01930	8.78e-262	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KGFKFCOI_01932	1.47e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
KGFKFCOI_01933	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
KGFKFCOI_01934	1.16e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KGFKFCOI_01935	1.25e-208	hgd	1.1.1.31, 1.1.1.60	-	I	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
KGFKFCOI_01936	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_01937	1.05e-251	-	-	-	I	-	-	-	3-hydroxyisobutyryl-CoA hydrolase
KGFKFCOI_01938	2.59e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KGFKFCOI_01939	6.5e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KGFKFCOI_01940	1.39e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KGFKFCOI_01941	6.41e-111	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
KGFKFCOI_01942	2.26e-161	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KGFKFCOI_01943	3.87e-126	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KGFKFCOI_01944	4.98e-137	-	-	-	K	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
KGFKFCOI_01945	0.0	acoD	-	-	C	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
KGFKFCOI_01946	9.28e-218	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
KGFKFCOI_01947	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGFKFCOI_01948	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
KGFKFCOI_01949	3.27e-60	-	-	-	S	-	-	-	ATP synthase, subunit b
KGFKFCOI_01950	1.56e-161	-	-	-	S	-	-	-	membrane
KGFKFCOI_01951	1.09e-58	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGFKFCOI_01952	5.44e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
KGFKFCOI_01953	5.15e-247	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
KGFKFCOI_01954	1.46e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
KGFKFCOI_01955	9.37e-276	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KGFKFCOI_01956	8.76e-131	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
KGFKFCOI_01957	2.1e-104	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
KGFKFCOI_01958	3.81e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KGFKFCOI_01959	5.06e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KGFKFCOI_01960	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
KGFKFCOI_01961	1.35e-282	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KGFKFCOI_01962	2.69e-167	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_01963	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_01965	2.85e-244	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_01966	3.67e-180	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KGFKFCOI_01967	1.18e-127	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
KGFKFCOI_01969	5e-175	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KGFKFCOI_01970	0.0	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KGFKFCOI_01971	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGFKFCOI_01972	2.77e-58	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
KGFKFCOI_01973	1.11e-242	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
KGFKFCOI_01974	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGFKFCOI_01975	3.63e-135	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
KGFKFCOI_01978	1.3e-69	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_01979	3.14e-52	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_01981	2.27e-289	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl Transferase
KGFKFCOI_01982	5e-253	-	-	GT4	M	ko:K13678	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KGFKFCOI_01983	1.94e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGFKFCOI_01985	1.59e-288	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KGFKFCOI_01986	3.54e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
KGFKFCOI_01987	5.4e-222	ycgE	-	-	K	ko:K22491	-	ko00000,ko03000	MerR family transcriptional regulator
KGFKFCOI_01988	8.17e-141	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KGFKFCOI_01989	2.41e-165	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_01990	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KGFKFCOI_01991	6.02e-246	-	-	-	-	-	-	-	-
KGFKFCOI_01992	7.53e-304	gudB	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KGFKFCOI_01993	6.07e-232	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
KGFKFCOI_01994	1.05e-230	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KGFKFCOI_01995	2.05e-146	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
KGFKFCOI_01996	8.25e-36	-	-	-	-	-	-	-	-
KGFKFCOI_01997	1.47e-268	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KGFKFCOI_01998	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KGFKFCOI_01999	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
KGFKFCOI_02000	4.76e-215	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
KGFKFCOI_02001	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
KGFKFCOI_02002	2.95e-170	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KGFKFCOI_02003	4.75e-138	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	1-acyl-sn-glycerol-3-phosphate acyltransferase
KGFKFCOI_02004	1.51e-260	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KGFKFCOI_02006	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KGFKFCOI_02007	3.54e-133	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGFKFCOI_02008	8.8e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KGFKFCOI_02009	5.25e-54	-	-	-	S	-	-	-	Stage VI sporulation protein F
KGFKFCOI_02010	8.81e-10	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
KGFKFCOI_02011	1.66e-174	yphF	-	-	-	-	-	-	-
KGFKFCOI_02012	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KGFKFCOI_02013	4.09e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
KGFKFCOI_02014	1.85e-48	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KGFKFCOI_02015	4.74e-73	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	heptaprenyl diphosphate synthase
KGFKFCOI_02016	3.84e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KGFKFCOI_02017	4.87e-203	ubiA	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KGFKFCOI_02018	2.97e-208	mqnA	4.2.1.151	-	S	ko:K11782	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KGFKFCOI_02019	2.93e-234	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KGFKFCOI_02020	6.26e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KGFKFCOI_02021	5.05e-188	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
KGFKFCOI_02022	3.58e-281	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KGFKFCOI_02023	1.18e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KGFKFCOI_02024	7.94e-78	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KGFKFCOI_02025	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KGFKFCOI_02026	9.51e-240	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KGFKFCOI_02027	2.66e-171	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
KGFKFCOI_02028	1.63e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosylanthranilate isomerase activity
KGFKFCOI_02029	3.61e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KGFKFCOI_02030	1.19e-190	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KGFKFCOI_02031	3.6e-265	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KGFKFCOI_02032	4.68e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KGFKFCOI_02033	4.93e-303	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGFKFCOI_02034	1.95e-294	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
KGFKFCOI_02035	4.13e-127	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
KGFKFCOI_02036	3.85e-108	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
KGFKFCOI_02037	3.64e-119	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
KGFKFCOI_02038	8.39e-159	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
KGFKFCOI_02039	2.15e-192	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
KGFKFCOI_02040	1.8e-141	ypjA	-	-	S	-	-	-	membrane
KGFKFCOI_02041	1.1e-180	-	-	-	S	-	-	-	Sporulation protein YpjB (SpoYpjB)
KGFKFCOI_02042	1.21e-151	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
KGFKFCOI_02043	9.3e-273	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
KGFKFCOI_02044	3.86e-202	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
KGFKFCOI_02045	2.69e-79	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
KGFKFCOI_02046	1.06e-186	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KGFKFCOI_02047	4.83e-98	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
KGFKFCOI_02048	3.48e-114	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_02049	7.81e-303	hint	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
KGFKFCOI_02050	3.33e-51	-	-	-	-	-	-	-	-
KGFKFCOI_02051	9.34e-101	yyaT	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_02052	5.69e-184	-	-	-	Q	-	-	-	Methyltransferase domain
KGFKFCOI_02053	3.68e-69	-	-	-	-	-	-	-	-
KGFKFCOI_02055	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KGFKFCOI_02056	3.05e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
KGFKFCOI_02057	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KGFKFCOI_02058	6.63e-173	yodH	-	-	Q	-	-	-	Methyltransferase
KGFKFCOI_02059	3.24e-221	-	-	-	M	-	-	-	3D domain
KGFKFCOI_02060	5.82e-232	-	-	-	M	-	-	-	3D domain
KGFKFCOI_02061	4.7e-204	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGFKFCOI_02062	7.25e-265	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
KGFKFCOI_02063	1.64e-196	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
KGFKFCOI_02064	7.48e-133	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
KGFKFCOI_02065	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KGFKFCOI_02066	1.62e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KGFKFCOI_02067	4.57e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KGFKFCOI_02068	7.37e-139	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KGFKFCOI_02069	1.28e-151	-	-	CBM50	M	ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
KGFKFCOI_02070	1.98e-301	-	-	-	S	-	-	-	Acetyltransferase
KGFKFCOI_02071	1.21e-135	yvdT	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_02072	1.58e-238	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFKFCOI_02073	9.74e-176	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
KGFKFCOI_02074	4.73e-241	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFKFCOI_02075	2.28e-219	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
KGFKFCOI_02076	3.92e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KGFKFCOI_02077	3.09e-78	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
KGFKFCOI_02078	0.0	asbA	-	-	Q	-	-	-	Siderophore biosynthesis protein
KGFKFCOI_02079	0.0	asbB	-	-	Q	-	-	-	IucA / IucC family
KGFKFCOI_02080	5.96e-304	asbC	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	AMP-binding enzyme C-terminal domain
KGFKFCOI_02081	1.56e-55	asbD	-	-	IQ	-	-	-	Phosphopantetheine attachment site
KGFKFCOI_02082	1.98e-244	asbE	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGFKFCOI_02083	3.22e-212	asbF	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
KGFKFCOI_02084	4.55e-130	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	D,D-heptose 1,7-bisphosphate phosphatase
KGFKFCOI_02085	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
KGFKFCOI_02086	4.91e-199	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KGFKFCOI_02087	1.67e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
KGFKFCOI_02090	4.62e-194	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
KGFKFCOI_02092	1.18e-72	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
KGFKFCOI_02093	5.41e-08	-	-	-	S	-	-	-	Putative methionine and alanine importer, small subunit
KGFKFCOI_02094	0.0	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KGFKFCOI_02095	3.33e-207	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
KGFKFCOI_02096	4.21e-126	-	-	-	K	-	-	-	Virulence activator alpha C-term
KGFKFCOI_02097	2.32e-113	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
KGFKFCOI_02098	2.8e-277	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_02099	2.15e-181	-	-	-	-	-	-	-	-
KGFKFCOI_02100	3.84e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
KGFKFCOI_02102	6.14e-15	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
KGFKFCOI_02103	5.58e-218	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_02104	9e-181	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KGFKFCOI_02105	1.1e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
KGFKFCOI_02107	1.03e-17	-	-	-	-	-	-	-	-
KGFKFCOI_02108	2.17e-12	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
KGFKFCOI_02109	8.12e-238	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
KGFKFCOI_02110	5.27e-95	-	-	-	S	-	-	-	Bacterial PH domain
KGFKFCOI_02111	9.89e-83	-	-	-	S	-	-	-	Belongs to the LOG family
KGFKFCOI_02112	1.84e-116	-	-	-	C	-	-	-	HEAT repeats
KGFKFCOI_02113	5.1e-165	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	This enzyme is an effector of chloramphenicol resistance in bacteria
KGFKFCOI_02114	1.72e-140	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
KGFKFCOI_02115	3.49e-48	-	-	-	K	-	-	-	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
KGFKFCOI_02116	6.29e-152	-	-	-	S	-	-	-	Golgi phosphoprotein 3 (GPP34)
KGFKFCOI_02117	1.44e-194	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
KGFKFCOI_02118	2.56e-180	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
KGFKFCOI_02119	1.27e-172	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
KGFKFCOI_02120	1.97e-259	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
KGFKFCOI_02121	1.5e-112	yocK	-	-	T	-	-	-	general stress protein
KGFKFCOI_02122	6.66e-79	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2200)
KGFKFCOI_02123	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGFKFCOI_02124	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGFKFCOI_02125	1.79e-92	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
KGFKFCOI_02126	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
KGFKFCOI_02127	1.66e-246	opuBA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KGFKFCOI_02128	1.24e-189	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_02129	8.78e-130	-	-	-	U	-	-	-	MarC family integral membrane protein
KGFKFCOI_02130	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KGFKFCOI_02131	6.83e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
KGFKFCOI_02132	1.17e-124	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
KGFKFCOI_02133	5.03e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
KGFKFCOI_02135	1.75e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
KGFKFCOI_02136	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KGFKFCOI_02137	1.12e-68	-	-	-	-	-	-	-	-
KGFKFCOI_02138	4.02e-91	-	-	-	S	-	-	-	Src homology 3 domains
KGFKFCOI_02139	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
KGFKFCOI_02140	1.68e-255	-	-	-	E	-	-	-	Spore germination protein
KGFKFCOI_02141	4.15e-258	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
KGFKFCOI_02143	4.49e-224	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KGFKFCOI_02144	6.96e-83	-	-	-	-	-	-	-	-
KGFKFCOI_02145	1.04e-83	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KGFKFCOI_02146	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
KGFKFCOI_02147	7.53e-239	-	-	-	S	-	-	-	Oxidoreductase
KGFKFCOI_02148	1.63e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KGFKFCOI_02149	4.7e-52	-	-	-	-	-	-	-	-
KGFKFCOI_02150	5.36e-271	-	-	-	L	ko:K07496	-	ko00000	Transposase
KGFKFCOI_02151	8.9e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
KGFKFCOI_02152	2.65e-64	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KGFKFCOI_02153	3.49e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KGFKFCOI_02154	3.2e-07	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
KGFKFCOI_02155	8.95e-293	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
KGFKFCOI_02156	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KGFKFCOI_02157	0.0	pepF	-	-	E	-	-	-	oligoendopeptidase F
KGFKFCOI_02158	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
KGFKFCOI_02159	1.07e-242	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
KGFKFCOI_02160	2.11e-272	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
KGFKFCOI_02161	8.66e-132	-	-	-	-	-	-	-	-
KGFKFCOI_02162	5.31e-149	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
KGFKFCOI_02163	8.79e-239	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
KGFKFCOI_02164	1.41e-28	-	-	-	-	-	-	-	-
KGFKFCOI_02165	2.31e-198	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
KGFKFCOI_02166	3.72e-116	-	-	-	-	-	-	-	-
KGFKFCOI_02167	2.9e-05	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
KGFKFCOI_02168	3.58e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGFKFCOI_02169	9.99e-86	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
KGFKFCOI_02170	3.24e-53	-	-	-	-	-	-	-	-
KGFKFCOI_02171	2.85e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
KGFKFCOI_02172	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KGFKFCOI_02173	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
KGFKFCOI_02175	2.89e-199	telA	-	-	P	-	-	-	Belongs to the TelA family
KGFKFCOI_02176	8.81e-215	-	-	-	-	-	-	-	-
KGFKFCOI_02177	7.61e-247	-	-	-	S	-	-	-	Protein of unknown function (DUF2777)
KGFKFCOI_02178	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
KGFKFCOI_02179	4.28e-112	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
KGFKFCOI_02180	5.49e-42	-	-	-	-	-	-	-	-
KGFKFCOI_02181	2.15e-201	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
KGFKFCOI_02182	1.7e-176	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
KGFKFCOI_02183	1.03e-96	-	-	-	CO	-	-	-	Thioredoxin-like
KGFKFCOI_02184	1.09e-100	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
KGFKFCOI_02185	3.99e-74	yusE	-	-	CO	-	-	-	cell redox homeostasis
KGFKFCOI_02186	1.38e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KGFKFCOI_02187	1.13e-125	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
KGFKFCOI_02188	6.68e-302	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KGFKFCOI_02189	2.9e-26	-	-	-	-	-	-	-	-
KGFKFCOI_02190	4.37e-81	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
KGFKFCOI_02191	1.92e-118	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KGFKFCOI_02193	3e-220	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
KGFKFCOI_02194	2.96e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KGFKFCOI_02195	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KGFKFCOI_02196	0.0	ypbR	-	-	S	-	-	-	Dynamin family
KGFKFCOI_02197	2.51e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KGFKFCOI_02198	6.12e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
KGFKFCOI_02199	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
KGFKFCOI_02200	1.8e-110	ypmB	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02201	8.74e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
KGFKFCOI_02203	3.83e-316	mtaD	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
KGFKFCOI_02204	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KGFKFCOI_02205	2.31e-229	-	-	-	S	-	-	-	Tetratricopeptide repeat
KGFKFCOI_02206	8.4e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KGFKFCOI_02207	1.67e-218	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KGFKFCOI_02208	2.4e-195	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KGFKFCOI_02209	1.1e-228	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KGFKFCOI_02210	1.17e-269	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KGFKFCOI_02211	1.71e-257	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
KGFKFCOI_02212	1.06e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
KGFKFCOI_02213	4.17e-37	-	-	-	-	-	-	-	-
KGFKFCOI_02214	1.02e-194	-	-	-	S	-	-	-	Nucleotidyltransferase domain
KGFKFCOI_02215	2.66e-215	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
KGFKFCOI_02216	7.35e-252	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
KGFKFCOI_02217	1.7e-148	-	-	-	S	-	-	-	CAAX protease self-immunity
KGFKFCOI_02218	3.39e-165	-	-	-	K	ko:K11922	-	ko00000,ko03000	UTRA
KGFKFCOI_02219	0.0	glvA	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGFKFCOI_02220	7.45e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
KGFKFCOI_02221	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KGFKFCOI_02224	4.03e-23	-	-	-	-	-	-	-	-
KGFKFCOI_02225	1.48e-22	-	-	-	-	-	-	-	-
KGFKFCOI_02226	1.75e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KGFKFCOI_02228	1.8e-164	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
KGFKFCOI_02229	0.0	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
KGFKFCOI_02230	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_02231	3.29e-181	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
KGFKFCOI_02232	8.62e-81	-	-	-	-	-	-	-	-
KGFKFCOI_02233	4.45e-128	-	-	-	S	-	-	-	DinB superfamily
KGFKFCOI_02234	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KGFKFCOI_02235	3.61e-77	-	-	-	-	-	-	-	-
KGFKFCOI_02236	8.77e-135	-	-	-	-	-	-	-	-
KGFKFCOI_02237	6.72e-161	-	-	-	-	-	-	-	-
KGFKFCOI_02238	9.17e-70	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_02240	4.67e-52	-	-	-	-	-	-	-	-
KGFKFCOI_02242	5.6e-308	-	-	-	S	-	-	-	membrane
KGFKFCOI_02243	6.52e-310	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
KGFKFCOI_02245	1.92e-92	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
KGFKFCOI_02246	3.57e-150	mucD	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGFKFCOI_02247	9.83e-81	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
KGFKFCOI_02248	1.15e-160	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
KGFKFCOI_02249	3.36e-218	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
KGFKFCOI_02250	1.3e-135	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_02251	1.09e-118	yocC	-	-	-	-	-	-	-
KGFKFCOI_02252	1.16e-76	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
KGFKFCOI_02253	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGFKFCOI_02254	2.25e-202	yvgN	-	-	S	-	-	-	reductase
KGFKFCOI_02255	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KGFKFCOI_02256	9.15e-45	yozC	-	-	-	-	-	-	-
KGFKFCOI_02257	2.1e-260	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KGFKFCOI_02258	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KGFKFCOI_02260	6.96e-264	-	-	-	Q	-	-	-	O-methyltransferase
KGFKFCOI_02261	3.88e-153	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
KGFKFCOI_02263	1.36e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
KGFKFCOI_02264	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGFKFCOI_02266	1.58e-221	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_02267	3.22e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KGFKFCOI_02268	3.25e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KGFKFCOI_02269	1.98e-259	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_02270	1.24e-137	-	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
KGFKFCOI_02272	1.13e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KGFKFCOI_02273	1.51e-161	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KGFKFCOI_02274	1.39e-101	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
KGFKFCOI_02275	8.12e-165	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KGFKFCOI_02276	1.58e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
KGFKFCOI_02277	0.0	agcS	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
KGFKFCOI_02278	1.95e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KGFKFCOI_02279	5.71e-58	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
KGFKFCOI_02280	2.19e-67	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
KGFKFCOI_02281	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
KGFKFCOI_02282	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KGFKFCOI_02283	7.16e-236	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KGFKFCOI_02284	3.94e-58	-	-	-	S	-	-	-	DNA alkylation repair protein
KGFKFCOI_02285	5.48e-281	-	-	-	I	ko:K01066	-	ko00000,ko01000	COG0657 Esterase lipase
KGFKFCOI_02286	2.57e-127	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGFKFCOI_02287	3.64e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
KGFKFCOI_02289	7.84e-207	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
KGFKFCOI_02290	1.18e-225	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
KGFKFCOI_02291	6.63e-95	hspX	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KGFKFCOI_02292	1.03e-47	-	-	-	S	-	-	-	YppG-like protein
KGFKFCOI_02293	1.28e-31	-	-	-	-	-	-	-	-
KGFKFCOI_02294	3.02e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
KGFKFCOI_02295	3.44e-200	-	-	-	I	-	-	-	Hydrolase
KGFKFCOI_02296	2.03e-230	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KGFKFCOI_02297	4.11e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
KGFKFCOI_02298	8.79e-199	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KGFKFCOI_02299	1.02e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
KGFKFCOI_02300	0.0	spoVK_1	-	-	O	-	-	-	stage V sporulation protein K
KGFKFCOI_02301	2.47e-188	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
KGFKFCOI_02302	4.21e-171	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
KGFKFCOI_02303	3.93e-17	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
KGFKFCOI_02304	2.3e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
KGFKFCOI_02305	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KGFKFCOI_02307	5.66e-19	-	-	-	-	-	-	-	-
KGFKFCOI_02308	2.93e-107	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
KGFKFCOI_02309	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_02310	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
KGFKFCOI_02311	8.21e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
KGFKFCOI_02312	5.64e-97	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
KGFKFCOI_02313	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KGFKFCOI_02314	2.51e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
KGFKFCOI_02315	8.37e-153	yneB	-	-	L	-	-	-	resolvase
KGFKFCOI_02317	8.11e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KGFKFCOI_02318	4.36e-283	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
KGFKFCOI_02320	2.2e-273	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGFKFCOI_02321	2.14e-127	-	-	-	FG	-	-	-	Domain of unknown function (DUF4269)
KGFKFCOI_02322	8.41e-119	-	-	-	-	-	-	-	-
KGFKFCOI_02323	2.49e-177	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
KGFKFCOI_02324	5.46e-184	-	-	-	Q	-	-	-	Domain of unknown function (DUF2437)
KGFKFCOI_02325	0.0	glcB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KGFKFCOI_02326	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
KGFKFCOI_02327	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
KGFKFCOI_02328	0.0	-	-	-	C	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	FAD binding domain
KGFKFCOI_02329	5.69e-100	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_02330	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KGFKFCOI_02331	1.24e-314	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KGFKFCOI_02332	2.02e-220	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
KGFKFCOI_02333	3.91e-245	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KGFKFCOI_02334	1.24e-47	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KGFKFCOI_02335	5e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KGFKFCOI_02336	2.05e-180	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
KGFKFCOI_02337	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KGFKFCOI_02338	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KGFKFCOI_02339	1.13e-133	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
KGFKFCOI_02340	1.1e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
KGFKFCOI_02341	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KGFKFCOI_02342	7.83e-200	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
KGFKFCOI_02343	7.82e-51	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
KGFKFCOI_02344	8.12e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
KGFKFCOI_02345	3.81e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KGFKFCOI_02346	1.33e-149	-	-	-	L	-	-	-	DNA recombination
KGFKFCOI_02347	1.02e-10	-	-	-	-	-	-	-	-
KGFKFCOI_02348	0.0	-	-	-	L	-	-	-	AAA domain
KGFKFCOI_02349	1.41e-240	-	-	-	L	-	-	-	Calcineurin-like phosphoesterase superfamily domain
KGFKFCOI_02350	1.47e-243	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KGFKFCOI_02351	0.0	deaD	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGFKFCOI_02352	7.13e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KGFKFCOI_02353	2.85e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGFKFCOI_02354	1.58e-188	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
KGFKFCOI_02355	5.43e-180	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
KGFKFCOI_02356	3.99e-53	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
KGFKFCOI_02357	1.81e-160	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_02358	0.0	ymfH	-	-	S	-	-	-	zinc protease
KGFKFCOI_02359	2.01e-304	albE	-	-	S	-	-	-	Peptidase M16
KGFKFCOI_02360	2.49e-167	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_02361	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KGFKFCOI_02362	3.72e-06	-	-	-	S	-	-	-	YlzJ-like protein
KGFKFCOI_02363	3.79e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
KGFKFCOI_02364	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGFKFCOI_02365	1.26e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGFKFCOI_02366	1.52e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KGFKFCOI_02367	2.27e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KGFKFCOI_02368	3.23e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KGFKFCOI_02369	1.15e-205	spoVFA	-	-	E	ko:K06410	-	ko00000	subunit a
KGFKFCOI_02370	5.31e-49	ymxH	-	-	S	-	-	-	YlmC YmxH family
KGFKFCOI_02371	1.81e-290	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
KGFKFCOI_02372	1.36e-244	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
KGFKFCOI_02373	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KGFKFCOI_02374	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KGFKFCOI_02375	1.49e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KGFKFCOI_02376	6.31e-223	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KGFKFCOI_02377	2.49e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KGFKFCOI_02378	5.12e-56	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
KGFKFCOI_02379	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KGFKFCOI_02380	2.49e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
KGFKFCOI_02381	1.42e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
KGFKFCOI_02382	3.99e-257	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KGFKFCOI_02383	9.4e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KGFKFCOI_02384	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGFKFCOI_02385	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KGFKFCOI_02386	3.42e-297	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KGFKFCOI_02387	1.16e-266	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KGFKFCOI_02388	7.6e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KGFKFCOI_02389	2.61e-188	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KGFKFCOI_02390	6.48e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KGFKFCOI_02391	1.18e-160	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KGFKFCOI_02392	5.04e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KGFKFCOI_02393	5.65e-171	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KGFKFCOI_02394	8.61e-06	ylxL	-	-	-	-	-	-	-
KGFKFCOI_02395	7.05e-171	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_02396	7.7e-110	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KGFKFCOI_02397	3.87e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KGFKFCOI_02398	3.12e-222	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KGFKFCOI_02399	3.09e-127	-	-	-	-	-	-	-	-
KGFKFCOI_02400	3.28e-232	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
KGFKFCOI_02401	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KGFKFCOI_02402	4.54e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KGFKFCOI_02403	1.93e-171	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
KGFKFCOI_02404	8.01e-54	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
KGFKFCOI_02405	1.04e-145	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
KGFKFCOI_02406	1.04e-140	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
KGFKFCOI_02407	2.57e-78	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
KGFKFCOI_02408	5.01e-274	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KGFKFCOI_02409	1.13e-225	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KGFKFCOI_02410	1.61e-92	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
KGFKFCOI_02411	3.86e-38	flbD	-	-	N	ko:K02385	-	ko00000,ko02035	protein, possibly involved in motility
KGFKFCOI_02412	6.89e-189	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
KGFKFCOI_02413	4.43e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
KGFKFCOI_02414	0.0	-	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein FliK
KGFKFCOI_02416	2.64e-93	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
KGFKFCOI_02417	2.93e-313	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KGFKFCOI_02418	9.41e-110	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
KGFKFCOI_02419	1.32e-227	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KGFKFCOI_02420	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
KGFKFCOI_02421	8.2e-58	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
KGFKFCOI_02422	6.48e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
KGFKFCOI_02423	2.47e-88	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KGFKFCOI_02424	2.27e-174	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KGFKFCOI_02425	7.5e-301	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KGFKFCOI_02426	1.05e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KGFKFCOI_02427	7.91e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
KGFKFCOI_02428	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KGFKFCOI_02429	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGFKFCOI_02430	2.08e-221	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
KGFKFCOI_02431	3.09e-215	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KGFKFCOI_02432	1.27e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KGFKFCOI_02433	5.58e-104	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	FlhB HrpN YscU SpaS Family
KGFKFCOI_02435	2.38e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGFKFCOI_02436	5.1e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KGFKFCOI_02437	7.13e-134	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KGFKFCOI_02438	1.1e-10	-	-	-	-	-	-	-	-
KGFKFCOI_02439	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KGFKFCOI_02440	0.0	-	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
KGFKFCOI_02441	1.76e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KGFKFCOI_02442	6.52e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KGFKFCOI_02443	2.5e-90	-	-	-	S	-	-	-	YlqD protein
KGFKFCOI_02444	9.51e-47	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KGFKFCOI_02445	7.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KGFKFCOI_02446	5.06e-314	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KGFKFCOI_02447	3.83e-68	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KGFKFCOI_02448	3.38e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KGFKFCOI_02449	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KGFKFCOI_02450	2.38e-14	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
KGFKFCOI_02451	1.55e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KGFKFCOI_02452	1.35e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGFKFCOI_02453	1.04e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KGFKFCOI_02454	1.6e-219	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
KGFKFCOI_02455	5.46e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KGFKFCOI_02456	3.76e-128	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KGFKFCOI_02457	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KGFKFCOI_02458	6.57e-197	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
KGFKFCOI_02459	2.23e-157	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
KGFKFCOI_02460	1.18e-194	yitS	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02461	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
KGFKFCOI_02462	1.81e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02463	4.09e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KGFKFCOI_02465	2.71e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KGFKFCOI_02466	7.3e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KGFKFCOI_02467	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KGFKFCOI_02468	2.78e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KGFKFCOI_02469	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KGFKFCOI_02470	1.43e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGFKFCOI_02471	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGFKFCOI_02472	1.02e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KGFKFCOI_02473	5.59e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KGFKFCOI_02474	3.88e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KGFKFCOI_02475	1.15e-52	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
KGFKFCOI_02476	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
KGFKFCOI_02477	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
KGFKFCOI_02478	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KGFKFCOI_02480	2.31e-156	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
KGFKFCOI_02481	7.28e-142	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KGFKFCOI_02482	2.39e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KGFKFCOI_02483	1.79e-214	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KGFKFCOI_02484	5.05e-187	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KGFKFCOI_02485	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
KGFKFCOI_02486	2.55e-270	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KGFKFCOI_02487	5.87e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KGFKFCOI_02488	1.59e-211	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KGFKFCOI_02489	7.11e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
KGFKFCOI_02490	2.85e-135	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGFKFCOI_02491	5.41e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KGFKFCOI_02492	8.13e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KGFKFCOI_02493	9.51e-148	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
KGFKFCOI_02494	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KGFKFCOI_02495	2.64e-96	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
KGFKFCOI_02496	3.83e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
KGFKFCOI_02497	7.03e-58	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
KGFKFCOI_02498	2.04e-94	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KGFKFCOI_02499	4.27e-155	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KGFKFCOI_02500	1.95e-191	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
KGFKFCOI_02501	6.23e-62	ylmC	-	-	S	-	-	-	sporulation protein
KGFKFCOI_02502	3.67e-181	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_02503	8.95e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_02504	4.54e-209	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KGFKFCOI_02505	1.02e-241	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KGFKFCOI_02506	1.02e-295	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KGFKFCOI_02508	1.27e-173	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KGFKFCOI_02509	5.14e-247	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KGFKFCOI_02510	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KGFKFCOI_02511	9.92e-218	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGFKFCOI_02512	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KGFKFCOI_02513	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGFKFCOI_02514	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
KGFKFCOI_02515	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KGFKFCOI_02516	1.12e-71	ftsL	-	-	D	-	-	-	cell division protein FtsL
KGFKFCOI_02517	2.28e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KGFKFCOI_02518	4.81e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KGFKFCOI_02519	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KGFKFCOI_02521	9.16e-208	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGFKFCOI_02522	2.19e-121	ylbP	-	-	K	-	-	-	n-acetyltransferase
KGFKFCOI_02523	4.67e-104	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KGFKFCOI_02524	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KGFKFCOI_02525	4.91e-121	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
KGFKFCOI_02526	1.96e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KGFKFCOI_02527	4.78e-249	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KGFKFCOI_02528	1e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
KGFKFCOI_02529	3.72e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
KGFKFCOI_02530	1.28e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KGFKFCOI_02531	1.44e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
KGFKFCOI_02532	3.58e-85	-	-	-	S	-	-	-	Methylthioribose kinase
KGFKFCOI_02533	4.89e-63	ylbG	-	-	S	-	-	-	UPF0298 protein
KGFKFCOI_02534	4.07e-92	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
KGFKFCOI_02535	6.64e-186	-	-	-	HJ	ko:K05844	-	ko00000,ko01000,ko03009	Prokaryotic glutathione synthetase, ATP-grasp domain
KGFKFCOI_02536	7.5e-43	ylbE	-	-	S	-	-	-	YlbE-like protein
KGFKFCOI_02537	5.03e-95	ylbD	-	-	S	-	-	-	Putative coat protein
KGFKFCOI_02538	2.89e-110	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
KGFKFCOI_02539	2.2e-272	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
KGFKFCOI_02540	1.34e-83	ylbA	-	-	S	-	-	-	YugN-like family
KGFKFCOI_02541	2.37e-110	-	-	-	-	-	-	-	-
KGFKFCOI_02542	1.13e-120	yozB	-	-	S	ko:K08976	-	ko00000	membrane
KGFKFCOI_02543	7.24e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KGFKFCOI_02544	8.77e-144	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KGFKFCOI_02545	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KGFKFCOI_02546	4.12e-254	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KGFKFCOI_02547	6.42e-205	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KGFKFCOI_02548	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KGFKFCOI_02549	1.92e-56	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
KGFKFCOI_02550	6.72e-123	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KGFKFCOI_02551	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
KGFKFCOI_02552	1.3e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02553	3.25e-70	ylaH	-	-	S	-	-	-	YlaH-like protein
KGFKFCOI_02554	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KGFKFCOI_02555	1.13e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
KGFKFCOI_02556	2.35e-212	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KGFKFCOI_02557	3.73e-198	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
KGFKFCOI_02558	1.71e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
KGFKFCOI_02559	7.65e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KGFKFCOI_02560	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
KGFKFCOI_02561	1.06e-298	-	-	-	O	-	-	-	Peptidase family M48
KGFKFCOI_02562	2.51e-195	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
KGFKFCOI_02563	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
KGFKFCOI_02564	6.88e-89	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
KGFKFCOI_02565	8.8e-210	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_02566	3.37e-223	-	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_02567	0.0	appA_2	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_02568	5.5e-238	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_02569	3.07e-239	appD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_02570	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KGFKFCOI_02571	6.67e-248	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGFKFCOI_02572	1.5e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGFKFCOI_02573	3.83e-256	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGFKFCOI_02574	8.8e-133	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
KGFKFCOI_02575	1.8e-33	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
KGFKFCOI_02576	2.58e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGFKFCOI_02577	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KGFKFCOI_02578	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGFKFCOI_02579	6.6e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
KGFKFCOI_02580	3.06e-108	ykuV	-	-	CO	-	-	-	thiol-disulfide
KGFKFCOI_02581	3.15e-131	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
KGFKFCOI_02582	3.77e-173	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
KGFKFCOI_02583	1.46e-50	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
KGFKFCOI_02584	1.96e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KGFKFCOI_02585	9.3e-292	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
KGFKFCOI_02586	2.79e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KGFKFCOI_02587	2.62e-188	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KGFKFCOI_02588	4.39e-244	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGFKFCOI_02589	5.65e-256	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
KGFKFCOI_02591	1.25e-127	copC	-	-	S	ko:K07156	-	ko00000,ko02000	CopC domain
KGFKFCOI_02592	3.27e-237	ytvI	-	-	S	-	-	-	AI-2E family transporter
KGFKFCOI_02593	2.99e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
KGFKFCOI_02594	1.64e-290	-	-	-	E	-	-	-	Peptidase family M28
KGFKFCOI_02595	8.56e-247	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KGFKFCOI_02597	1.14e-128	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KGFKFCOI_02598	9.47e-39	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
KGFKFCOI_02599	1.16e-62	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
KGFKFCOI_02600	1.66e-42	-	-	-	-	-	-	-	-
KGFKFCOI_02601	1.29e-188	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
KGFKFCOI_02603	8.3e-78	-	-	-	-	-	-	-	-
KGFKFCOI_02604	2.91e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
KGFKFCOI_02605	8.99e-293	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGFKFCOI_02606	4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGFKFCOI_02607	2.17e-241	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGFKFCOI_02608	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KGFKFCOI_02609	3.58e-263	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KGFKFCOI_02610	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
KGFKFCOI_02611	3.32e-48	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
KGFKFCOI_02612	4.19e-154	-	-	-	M	-	-	-	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGFKFCOI_02613	8.04e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KGFKFCOI_02614	9.21e-305	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
KGFKFCOI_02615	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KGFKFCOI_02616	6.48e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KGFKFCOI_02617	2.32e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
KGFKFCOI_02618	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KGFKFCOI_02619	2.41e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KGFKFCOI_02620	2.03e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGFKFCOI_02621	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGFKFCOI_02622	1.22e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KGFKFCOI_02623	5.96e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02624	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KGFKFCOI_02625	7.32e-105	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KGFKFCOI_02626	3.08e-74	-	-	-	-	-	-	-	-
KGFKFCOI_02627	2.98e-117	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
KGFKFCOI_02628	1.05e-146	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
KGFKFCOI_02629	1.76e-124	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
KGFKFCOI_02630	7.49e-263	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
KGFKFCOI_02631	6.3e-54	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
KGFKFCOI_02632	1.98e-40	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
KGFKFCOI_02633	6.16e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
KGFKFCOI_02634	2.02e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
KGFKFCOI_02635	3.84e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
KGFKFCOI_02636	9.91e-68	-	-	-	S	-	-	-	YfzA-like protein
KGFKFCOI_02637	3.54e-128	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KGFKFCOI_02638	7.96e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGFKFCOI_02639	5.61e-251	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
KGFKFCOI_02640	4.42e-116	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
KGFKFCOI_02641	2.46e-79	-	-	-	-	-	-	-	-
KGFKFCOI_02642	1.47e-213	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
KGFKFCOI_02643	6.58e-101	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KGFKFCOI_02644	5.42e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
KGFKFCOI_02645	1.03e-203	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KGFKFCOI_02646	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGFKFCOI_02647	6.16e-197	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KGFKFCOI_02648	4.68e-82	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
KGFKFCOI_02649	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KGFKFCOI_02650	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KGFKFCOI_02651	1.46e-263	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
KGFKFCOI_02652	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
KGFKFCOI_02653	3.45e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
KGFKFCOI_02655	1.85e-155	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
KGFKFCOI_02656	2.65e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
KGFKFCOI_02659	4.4e-106	-	-	-	-	-	-	-	-
KGFKFCOI_02661	5.75e-98	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
KGFKFCOI_02662	1.22e-64	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
KGFKFCOI_02663	3.58e-55	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KGFKFCOI_02673	8.18e-243	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
KGFKFCOI_02674	2e-241	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KGFKFCOI_02675	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KGFKFCOI_02676	4.39e-97	-	-	-	-	-	-	-	-
KGFKFCOI_02677	1.88e-113	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
KGFKFCOI_02678	6.94e-07	-	-	-	-	-	-	-	-
KGFKFCOI_02680	1.77e-176	-	-	-	-	-	-	-	-
KGFKFCOI_02681	3.67e-164	-	-	-	-	-	-	-	-
KGFKFCOI_02682	1.91e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
KGFKFCOI_02683	7.52e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1360)
KGFKFCOI_02684	4.28e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
KGFKFCOI_02685	1.95e-221	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KGFKFCOI_02686	5.27e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGFKFCOI_02687	1.02e-142	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
KGFKFCOI_02688	3.74e-82	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
KGFKFCOI_02689	1.37e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_02690	4.71e-142	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KGFKFCOI_02691	1.67e-95	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
KGFKFCOI_02692	2.68e-223	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
KGFKFCOI_02694	1.24e-303	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KGFKFCOI_02695	5.5e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KGFKFCOI_02696	2.03e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KGFKFCOI_02698	2.05e-127	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_02699	2.74e-302	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
KGFKFCOI_02700	1.83e-12	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
KGFKFCOI_02701	1.5e-144	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
KGFKFCOI_02702	1.83e-129	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
KGFKFCOI_02703	1.54e-137	-	-	-	CO	-	-	-	Redoxin
KGFKFCOI_02705	6.64e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
KGFKFCOI_02706	1.94e-15	-	-	-	-	-	-	-	-
KGFKFCOI_02707	8.42e-185	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
KGFKFCOI_02708	3.59e-202	yjaZ	-	-	O	-	-	-	Zn-dependent protease
KGFKFCOI_02709	1.49e-176	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
KGFKFCOI_02710	2.22e-230	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KGFKFCOI_02711	2.77e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
KGFKFCOI_02712	1.16e-134	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
KGFKFCOI_02714	0.0	-	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Poly A polymerase head domain
KGFKFCOI_02715	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_02716	1.28e-294	fabF	2.3.1.179	-	I	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGFKFCOI_02717	1.53e-214	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGFKFCOI_02719	7.3e-19	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	Competence protein ComG
KGFKFCOI_02720	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KGFKFCOI_02721	5.73e-203	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
KGFKFCOI_02722	6.55e-155	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
KGFKFCOI_02723	2.19e-220	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KGFKFCOI_02724	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
KGFKFCOI_02725	2.17e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KGFKFCOI_02726	7.44e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
KGFKFCOI_02727	1.18e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KGFKFCOI_02728	1.32e-289	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KGFKFCOI_02729	3.4e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KGFKFCOI_02730	1.17e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
KGFKFCOI_02731	1.57e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
KGFKFCOI_02732	2.72e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_02733	1.78e-140	-	-	-	-	-	-	-	-
KGFKFCOI_02734	2.05e-296	ywqB	-	-	S	-	-	-	zinc ion binding
KGFKFCOI_02735	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
KGFKFCOI_02737	6.44e-18	-	-	-	S	-	-	-	Intracellular proteinase inhibitor
KGFKFCOI_02738	7.65e-188	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
KGFKFCOI_02739	5.49e-192	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KGFKFCOI_02740	1.01e-56	-	-	-	-	-	-	-	-
KGFKFCOI_02741	2.36e-84	ytwF	-	-	P	-	-	-	Sulfurtransferase
KGFKFCOI_02742	2.04e-118	-	-	-	-	-	-	-	-
KGFKFCOI_02743	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KGFKFCOI_02744	6.94e-200	ykgA	-	-	E	-	-	-	Amidinotransferase
KGFKFCOI_02746	7.4e-93	yxxG	-	-	-	-	-	-	-
KGFKFCOI_02747	3e-132	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
KGFKFCOI_02749	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
KGFKFCOI_02750	1.59e-64	-	-	-	S	-	-	-	IDEAL
KGFKFCOI_02751	0.0	asnH	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KGFKFCOI_02752	1.74e-96	cheW	-	-	NT	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	chemotaxis
KGFKFCOI_02753	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
KGFKFCOI_02754	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KGFKFCOI_02755	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	exonuclease activity
KGFKFCOI_02756	4.58e-82	-	-	-	-	-	-	-	-
KGFKFCOI_02757	6.09e-144	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KGFKFCOI_02758	1.5e-184	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGFKFCOI_02759	3.69e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGFKFCOI_02760	2.52e-205	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
KGFKFCOI_02761	4.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KGFKFCOI_02762	1.04e-214	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KGFKFCOI_02763	1.18e-108	-	-	-	S	-	-	-	DinB family
KGFKFCOI_02764	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KGFKFCOI_02765	1.45e-171	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
KGFKFCOI_02766	3.51e-274	-	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
KGFKFCOI_02767	9.12e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
KGFKFCOI_02769	1.68e-276	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
KGFKFCOI_02770	2.47e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
KGFKFCOI_02771	1.58e-59	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KGFKFCOI_02772	5.37e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
KGFKFCOI_02773	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KGFKFCOI_02774	0.0	cafA	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
KGFKFCOI_02775	7.19e-198	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
KGFKFCOI_02776	9.49e-170	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
KGFKFCOI_02777	3.64e-219	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
KGFKFCOI_02778	2.86e-121	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
KGFKFCOI_02779	2.17e-97	-	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaC family
KGFKFCOI_02780	4.46e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
KGFKFCOI_02781	6.84e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
KGFKFCOI_02782	9.38e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KGFKFCOI_02783	1.48e-103	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
KGFKFCOI_02784	1.02e-203	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KGFKFCOI_02785	4.89e-239	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
KGFKFCOI_02786	2.48e-157	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
KGFKFCOI_02787	4.42e-136	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
KGFKFCOI_02788	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
KGFKFCOI_02789	2.89e-252	-	-	-	-	ko:K06380	-	ko00000	-
KGFKFCOI_02790	2.26e-155	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KGFKFCOI_02791	6.87e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KGFKFCOI_02792	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KGFKFCOI_02793	2.36e-42	-	-	-	-	-	-	-	-
KGFKFCOI_02794	3.32e-150	-	-	-	-	-	-	-	-
KGFKFCOI_02795	3.09e-245	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KGFKFCOI_02796	1.94e-211	-	-	-	-	-	-	-	-
KGFKFCOI_02797	3.65e-253	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
KGFKFCOI_02798	2.13e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
KGFKFCOI_02799	6.91e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
KGFKFCOI_02800	1.75e-179	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
KGFKFCOI_02801	4.76e-218	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KGFKFCOI_02802	2.21e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
KGFKFCOI_02803	0.0	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KGFKFCOI_02804	2.65e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KGFKFCOI_02805	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KGFKFCOI_02806	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
KGFKFCOI_02807	2.85e-303	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KGFKFCOI_02808	1.97e-295	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KGFKFCOI_02809	1.09e-230	ysoA	-	-	O	-	-	-	COG0457 FOG TPR repeat
KGFKFCOI_02810	3.49e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGFKFCOI_02811	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGFKFCOI_02812	3.13e-252	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KGFKFCOI_02813	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KGFKFCOI_02814	2.5e-235	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KGFKFCOI_02815	5.26e-112	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KGFKFCOI_02816	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
KGFKFCOI_02817	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
KGFKFCOI_02818	8.81e-98	-	-	-	-	-	-	-	-
KGFKFCOI_02819	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
KGFKFCOI_02820	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
KGFKFCOI_02824	1.59e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KGFKFCOI_02825	6e-142	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KGFKFCOI_02826	5.64e-175	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KGFKFCOI_02827	4.75e-249	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
KGFKFCOI_02828	3.77e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
KGFKFCOI_02829	3.13e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
KGFKFCOI_02830	5.46e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KGFKFCOI_02831	4e-105	ysmB	-	-	K	-	-	-	transcriptional
KGFKFCOI_02832	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGFKFCOI_02833	2.33e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
KGFKFCOI_02834	2.77e-45	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_02835	5.51e-106	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
KGFKFCOI_02836	4.17e-186	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
KGFKFCOI_02837	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
KGFKFCOI_02838	5.12e-145	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
KGFKFCOI_02839	1.82e-295	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
KGFKFCOI_02840	4.32e-100	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KGFKFCOI_02841	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KGFKFCOI_02842	1.37e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KGFKFCOI_02843	1.13e-223	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
KGFKFCOI_02844	7.35e-174	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
KGFKFCOI_02845	3.4e-179	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
KGFKFCOI_02846	2.65e-135	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_02847	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGFKFCOI_02848	7.25e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
KGFKFCOI_02849	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGFKFCOI_02850	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
KGFKFCOI_02851	5.01e-118	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
KGFKFCOI_02852	6.35e-46	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KGFKFCOI_02853	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGFKFCOI_02854	8.23e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KGFKFCOI_02855	5.88e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGFKFCOI_02856	3.13e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
KGFKFCOI_02858	1.45e-22	-	-	-	-	-	-	-	-
KGFKFCOI_02859	1.84e-260	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
KGFKFCOI_02860	7.91e-86	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
KGFKFCOI_02861	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGFKFCOI_02862	9.32e-70	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
KGFKFCOI_02863	5.42e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KGFKFCOI_02864	7.54e-40	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KGFKFCOI_02865	4.04e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KGFKFCOI_02866	1.48e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
KGFKFCOI_02867	2.79e-153	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_02868	7.63e-305	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KGFKFCOI_02869	8.9e-168	-	-	-	-	-	-	-	-
KGFKFCOI_02870	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
KGFKFCOI_02871	3.98e-229	-	-	-	C	-	-	-	Aldo/keto reductase family
KGFKFCOI_02872	6.99e-242	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_02873	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGFKFCOI_02874	1.16e-208	ytxC	-	-	S	-	-	-	YtxC-like family
KGFKFCOI_02875	1.41e-287	mqnC	1.21.98.1	-	H	ko:K11784	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
KGFKFCOI_02876	1.48e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KGFKFCOI_02877	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
KGFKFCOI_02878	1.52e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KGFKFCOI_02879	6.77e-87	-	-	-	-	-	-	-	-
KGFKFCOI_02880	2.59e-89	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KGFKFCOI_02881	4.26e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGFKFCOI_02882	2.44e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KGFKFCOI_02883	3.68e-136	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
KGFKFCOI_02884	7.85e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGFKFCOI_02885	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KGFKFCOI_02886	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
KGFKFCOI_02887	2.8e-170	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_02888	1.16e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
KGFKFCOI_02889	7.32e-219	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
KGFKFCOI_02890	1.08e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
KGFKFCOI_02891	1.53e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
KGFKFCOI_02892	4.98e-96	-	-	-	S	-	-	-	UPF0756 membrane protein
KGFKFCOI_02893	6.55e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
KGFKFCOI_02894	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KGFKFCOI_02895	1.14e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KGFKFCOI_02896	1.68e-229	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KGFKFCOI_02897	9.45e-198	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KGFKFCOI_02898	1.75e-150	lutR_1	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KGFKFCOI_02899	1.04e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
KGFKFCOI_02900	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KGFKFCOI_02901	4.62e-70	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
KGFKFCOI_02902	1.03e-117	ytrI	-	-	-	-	-	-	-
KGFKFCOI_02903	7.67e-223	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
KGFKFCOI_02904	3.35e-11	ytpI	-	-	S	-	-	-	YtpI-like protein
KGFKFCOI_02905	2.37e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
KGFKFCOI_02907	1.45e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
KGFKFCOI_02908	3.91e-269	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
KGFKFCOI_02909	1.35e-85	-	-	-	-	-	-	-	-
KGFKFCOI_02910	8.7e-179	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_02912	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KGFKFCOI_02913	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KGFKFCOI_02915	5.8e-219	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
KGFKFCOI_02916	1.23e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGFKFCOI_02917	1.19e-231	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
KGFKFCOI_02918	3.35e-111	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KGFKFCOI_02919	8.63e-258	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_02920	1.19e-97	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
KGFKFCOI_02921	5.89e-161	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
KGFKFCOI_02922	1.14e-129	yteJ	-	-	S	-	-	-	RDD family
KGFKFCOI_02923	2.4e-231	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
KGFKFCOI_02924	1.17e-38	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
KGFKFCOI_02925	2.36e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGFKFCOI_02926	7.02e-268	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
KGFKFCOI_02927	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KGFKFCOI_02928	8.97e-191	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KGFKFCOI_02929	3.71e-147	yttP	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_02930	2.2e-115	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KGFKFCOI_02931	8.51e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KGFKFCOI_02932	2.24e-300	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KGFKFCOI_02933	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG0744 Membrane carboxypeptidase (penicillin-binding protein)
KGFKFCOI_02934	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KGFKFCOI_02935	1.41e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KGFKFCOI_02936	4.31e-149	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
KGFKFCOI_02937	5.67e-303	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
KGFKFCOI_02938	1.24e-237	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KGFKFCOI_02939	4.11e-252	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KGFKFCOI_02940	3.48e-29	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
KGFKFCOI_02941	1.68e-84	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KGFKFCOI_02942	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KGFKFCOI_02943	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KGFKFCOI_02944	1.64e-136	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGFKFCOI_02945	2.92e-189	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
KGFKFCOI_02946	6.89e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
KGFKFCOI_02947	2.47e-189	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
KGFKFCOI_02948	5.77e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
KGFKFCOI_02949	5.57e-118	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KGFKFCOI_02950	1.92e-263	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
KGFKFCOI_02951	2.23e-65	ytzB	-	-	-	-	-	-	-
KGFKFCOI_02952	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KGFKFCOI_02954	1.35e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
KGFKFCOI_02955	4.39e-211	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KGFKFCOI_02956	5.2e-167	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_02957	5.57e-70	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
KGFKFCOI_02958	2.24e-282	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGFKFCOI_02959	6.28e-248	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGFKFCOI_02960	9.76e-229	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KGFKFCOI_02961	4.04e-279	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KGFKFCOI_02962	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
KGFKFCOI_02963	4.53e-148	cidB	-	-	M	-	-	-	effector of murein hydrolase
KGFKFCOI_02964	1.41e-84	-	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KGFKFCOI_02965	2.3e-140	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KGFKFCOI_02966	4.6e-220	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KGFKFCOI_02967	2.36e-213	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
KGFKFCOI_02968	3.06e-64	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
KGFKFCOI_02969	1.63e-195	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_02970	8.58e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KGFKFCOI_02971	4.69e-43	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
KGFKFCOI_02972	1.28e-172	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KGFKFCOI_02973	1.8e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KGFKFCOI_02974	3.03e-258	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KGFKFCOI_02975	0.0	ytgP	-	-	S	ko:K03328,ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGFKFCOI_02976	1.04e-217	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
KGFKFCOI_02977	7.86e-96	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
KGFKFCOI_02978	1.12e-291	yhaA1	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KGFKFCOI_02979	1.25e-82	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
KGFKFCOI_02981	2.78e-274	-	-	-	-	-	-	-	-
KGFKFCOI_02983	2.36e-27	-	-	-	-	-	-	-	-
KGFKFCOI_02984	4.73e-89	yqiX	-	-	S	-	-	-	YolD-like protein
KGFKFCOI_02985	4.83e-201	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
KGFKFCOI_02987	9.81e-69	-	-	-	-	-	-	-	-
KGFKFCOI_02988	1.11e-107	-	-	-	-	-	-	-	-
KGFKFCOI_02990	1.73e-289	-	-	-	L	-	-	-	Transposase IS116/IS110/IS902 family
KGFKFCOI_02992	2.12e-230	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
KGFKFCOI_02994	3.52e-58	-	-	-	-	-	-	-	-
KGFKFCOI_02995	0.0	-	-	-	L	-	-	-	Prophage endopeptidase tail
KGFKFCOI_02998	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_02999	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
KGFKFCOI_03000	1.46e-202	-	-	-	S	-	-	-	Phage tail protein
KGFKFCOI_03001	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
KGFKFCOI_03002	4.25e-154	-	-	-	-	-	-	-	-
KGFKFCOI_03004	6.78e-100	-	-	-	-	-	-	-	-
KGFKFCOI_03005	5.52e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
KGFKFCOI_03006	1.53e-138	-	-	-	-	-	-	-	-
KGFKFCOI_03007	8.68e-105	-	-	-	-	-	-	-	-
KGFKFCOI_03008	4.11e-110	-	-	-	-	-	-	-	-
KGFKFCOI_03009	1.26e-77	-	-	-	-	-	-	-	-
KGFKFCOI_03010	4.46e-72	-	-	-	-	-	-	-	-
KGFKFCOI_03012	1.22e-89	-	-	-	S	-	-	-	Phage major capsid protein E
KGFKFCOI_03013	2.49e-87	-	-	-	-	-	-	-	-
KGFKFCOI_03014	9.98e-147	-	-	-	-	-	-	-	-
KGFKFCOI_03015	1.24e-259	-	-	-	S	-	-	-	Phage minor capsid protein 2
KGFKFCOI_03016	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_03017	0.0	-	-	-	S	-	-	-	Terminase RNAseH like domain
KGFKFCOI_03018	1.67e-95	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
KGFKFCOI_03023	3.15e-279	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
KGFKFCOI_03024	1.04e-98	-	-	-	-	-	-	-	-
KGFKFCOI_03025	1.66e-100	-	-	-	-	-	-	-	-
KGFKFCOI_03027	4.59e-118	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
KGFKFCOI_03029	2.85e-119	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
KGFKFCOI_03032	3.42e-97	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	single-stranded DNA binding
KGFKFCOI_03034	1.04e-213	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KGFKFCOI_03036	3.72e-114	-	-	-	S	-	-	-	HNH nucleases
KGFKFCOI_03037	4.32e-155	-	-	-	K	ko:K03086	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KGFKFCOI_03040	1.08e-190	-	-	-	L	ko:K02315	-	ko00000,ko03032	Bacterial dnaA protein
KGFKFCOI_03041	1.33e-182	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
KGFKFCOI_03042	6.88e-171	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
KGFKFCOI_03044	3.08e-47	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KGFKFCOI_03045	3.24e-79	-	-	-	-	-	-	-	-
KGFKFCOI_03047	7.22e-06	-	-	-	S	-	-	-	YopX protein
KGFKFCOI_03056	2.56e-162	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
KGFKFCOI_03057	1.2e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
KGFKFCOI_03061	1.51e-145	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Peptidase S24-like
KGFKFCOI_03062	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
KGFKFCOI_03063	9.17e-303	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
KGFKFCOI_03064	5.31e-90	-	-	-	-	-	-	-	-
KGFKFCOI_03065	1.12e-99	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
KGFKFCOI_03066	2.33e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
KGFKFCOI_03067	1.37e-310	-	-	-	S	ko:K12941	-	ko00000,ko01002	amidohydrolase
KGFKFCOI_03068	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KGFKFCOI_03069	1.15e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KGFKFCOI_03070	4.19e-263	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
KGFKFCOI_03072	7.9e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
KGFKFCOI_03073	8.11e-138	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
KGFKFCOI_03074	4.53e-195	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
KGFKFCOI_03075	2.59e-100	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KGFKFCOI_03076	1.42e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KGFKFCOI_03077	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KGFKFCOI_03078	8.15e-198	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KGFKFCOI_03079	7.17e-233	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KGFKFCOI_03080	1.14e-175	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KGFKFCOI_03081	5.58e-178	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KGFKFCOI_03082	5.41e-115	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KGFKFCOI_03083	1.65e-286	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_03084	5.16e-110	ywpF	-	-	S	-	-	-	YwpF-like protein
KGFKFCOI_03086	7.78e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KGFKFCOI_03087	6.97e-150	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
KGFKFCOI_03088	1.52e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
KGFKFCOI_03089	9.52e-141	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
KGFKFCOI_03090	1.01e-225	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
KGFKFCOI_03091	5.06e-194	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03092	1.63e-200	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03093	1.23e-207	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03094	2.05e-138	pgpB3	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
KGFKFCOI_03095	3.35e-305	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGFKFCOI_03096	4.63e-101	-	-	-	S	-	-	-	Putative small multi-drug export protein
KGFKFCOI_03097	2.95e-106	-	-	-	S	-	-	-	DinB superfamily
KGFKFCOI_03098	9.46e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
KGFKFCOI_03099	6e-110	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
KGFKFCOI_03100	9.87e-211	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KGFKFCOI_03101	4.56e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
KGFKFCOI_03102	3.78e-15	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KGFKFCOI_03104	2.25e-29	-	-	-	-	-	-	-	-
KGFKFCOI_03105	1.77e-93	yugN	-	-	S	-	-	-	YugN-like family
KGFKFCOI_03106	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KGFKFCOI_03107	1.58e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KGFKFCOI_03108	2.44e-288	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
KGFKFCOI_03109	2.41e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
KGFKFCOI_03110	7.86e-77	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
KGFKFCOI_03111	1.99e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
KGFKFCOI_03112	6.3e-177	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KGFKFCOI_03113	3.31e-283	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
KGFKFCOI_03114	7.3e-111	alaR	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03115	4.49e-112	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KGFKFCOI_03116	6.56e-187	-	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KGFKFCOI_03117	1.81e-55	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGFKFCOI_03118	1.56e-296	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
KGFKFCOI_03119	5.93e-60	-	-	-	-	-	-	-	-
KGFKFCOI_03120	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KGFKFCOI_03121	2.38e-103	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
KGFKFCOI_03122	1.2e-145	yuiC	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03123	2.23e-62	yuiB	-	-	S	-	-	-	Putative membrane protein
KGFKFCOI_03124	1.09e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KGFKFCOI_03125	3.18e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
KGFKFCOI_03126	3.34e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
KGFKFCOI_03127	5e-96	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KGFKFCOI_03128	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
KGFKFCOI_03129	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
KGFKFCOI_03130	3.3e-198	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KGFKFCOI_03131	2.45e-141	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
KGFKFCOI_03132	2.5e-79	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
KGFKFCOI_03133	3.32e-13	-	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
KGFKFCOI_03134	5.12e-267	mqnE	2.5.1.120	-	H	ko:K18285	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KGFKFCOI_03135	9.96e-210	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KGFKFCOI_03136	9.92e-57	-	-	-	-	-	-	-	-
KGFKFCOI_03137	3.63e-54	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
KGFKFCOI_03138	0.0	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KGFKFCOI_03139	6.51e-69	yuzD	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03140	4.25e-49	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
KGFKFCOI_03141	1.3e-208	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KGFKFCOI_03142	2.38e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KGFKFCOI_03143	1.03e-304	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KGFKFCOI_03144	5.3e-269	yutH	-	-	S	-	-	-	Spore coat protein
KGFKFCOI_03145	1.37e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
KGFKFCOI_03146	1.68e-176	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KGFKFCOI_03147	5.75e-103	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
KGFKFCOI_03148	1.79e-59	-	-	-	-	-	-	-	-
KGFKFCOI_03149	6.09e-67	yutD	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03150	7.13e-123	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KGFKFCOI_03151	3.12e-222	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KGFKFCOI_03152	3.22e-261	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
KGFKFCOI_03153	0.0	-	-	-	C	ko:K18218	-	ko00000,ko00002,ko01504,ko02000	Na+/H+ antiporter family
KGFKFCOI_03154	3.14e-179	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
KGFKFCOI_03155	1.61e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KGFKFCOI_03156	2.96e-202	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGFKFCOI_03157	6.82e-66	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
KGFKFCOI_03158	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KGFKFCOI_03159	8.56e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KGFKFCOI_03160	3.64e-217	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
KGFKFCOI_03161	1.7e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
KGFKFCOI_03162	1.26e-67	-	-	-	-	-	-	-	-
KGFKFCOI_03163	3.92e-192	-	-	-	-	-	-	-	-
KGFKFCOI_03164	2.77e-61	-	-	-	-	-	-	-	-
KGFKFCOI_03165	1.14e-305	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_03166	1.85e-58	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
KGFKFCOI_03167	3.1e-214	-	-	-	S	-	-	-	Phosphotransferase enzyme family
KGFKFCOI_03168	1.2e-235	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KGFKFCOI_03169	5.69e-195	msmR	-	-	K	-	-	-	AraC family transcriptional regulator
KGFKFCOI_03170	1.3e-240	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
KGFKFCOI_03171	4.17e-183	-	-	-	Q	-	-	-	Methyltransferase domain
KGFKFCOI_03172	4.74e-55	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
KGFKFCOI_03173	5.66e-70	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
KGFKFCOI_03174	2.61e-24	-	-	-	S	-	-	-	YhfH-like protein
KGFKFCOI_03175	3.1e-307	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
KGFKFCOI_03176	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
KGFKFCOI_03177	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
KGFKFCOI_03178	3.17e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KGFKFCOI_03179	2.3e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
KGFKFCOI_03180	8.04e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KGFKFCOI_03181	7.34e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KGFKFCOI_03182	3.35e-216	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KGFKFCOI_03183	5.64e-125	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
KGFKFCOI_03184	7.2e-200	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
KGFKFCOI_03185	8.98e-149	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
KGFKFCOI_03186	1.99e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGFKFCOI_03187	6.74e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KGFKFCOI_03188	1.43e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
KGFKFCOI_03189	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
KGFKFCOI_03190	8.7e-274	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
KGFKFCOI_03191	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
KGFKFCOI_03192	2.87e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGFKFCOI_03193	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
KGFKFCOI_03194	3.72e-166	-	-	-	S	-	-	-	Glycosyltransferase like family
KGFKFCOI_03195	1.71e-197	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
KGFKFCOI_03196	6.97e-09	-	-	-	-	-	-	-	-
KGFKFCOI_03197	1.16e-142	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KGFKFCOI_03198	0.0	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGFKFCOI_03199	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03200	1.23e-84	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGFKFCOI_03201	5.57e-135	-	-	-	-	-	-	-	-
KGFKFCOI_03202	3.26e-174	-	-	-	-	-	-	-	-
KGFKFCOI_03204	1.12e-104	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KGFKFCOI_03205	2.11e-80	-	-	-	S	ko:K15977	-	ko00000	DoxX
KGFKFCOI_03206	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KGFKFCOI_03207	1.29e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
KGFKFCOI_03208	4.6e-177	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	COG1647 Esterase lipase
KGFKFCOI_03209	1.64e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFKFCOI_03210	9.6e-38	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
KGFKFCOI_03211	9.92e-104	yclD	-	-	-	-	-	-	-
KGFKFCOI_03212	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_03213	2.39e-103	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
KGFKFCOI_03214	1e-221	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_03215	8.5e-286	-	4.2.1.158	-	M	ko:K20022	-	ko00000,ko01000	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
KGFKFCOI_03216	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_03217	1.81e-224	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
KGFKFCOI_03218	3.78e-156	-	-	-	K	-	-	-	FCD
KGFKFCOI_03219	9.59e-305	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGFKFCOI_03220	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
KGFKFCOI_03221	2.71e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGFKFCOI_03222	2.4e-278	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KGFKFCOI_03223	1.46e-240	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGFKFCOI_03224	1.05e-230	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KGFKFCOI_03225	2.33e-263	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03227	1.55e-55	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KGFKFCOI_03228	9.37e-311	sigL	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KGFKFCOI_03229	4.06e-134	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGFKFCOI_03230	8.35e-307	-	-	-	E	-	-	-	Peptidase dimerisation domain
KGFKFCOI_03231	7.15e-75	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
KGFKFCOI_03232	2.22e-277	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KGFKFCOI_03233	5.2e-139	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
KGFKFCOI_03234	1.8e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KGFKFCOI_03235	2.76e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
KGFKFCOI_03236	4.07e-52	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
KGFKFCOI_03237	2.16e-228	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KGFKFCOI_03238	1.09e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KGFKFCOI_03239	4.57e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KGFKFCOI_03240	1.28e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
KGFKFCOI_03241	1.01e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KGFKFCOI_03242	5.86e-254	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
KGFKFCOI_03243	4.59e-315	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
KGFKFCOI_03244	1.07e-188	-	-	-	K	-	-	-	FR47-like protein
KGFKFCOI_03245	5.1e-147	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
KGFKFCOI_03246	6.86e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KGFKFCOI_03247	8.99e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KGFKFCOI_03248	1.71e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KGFKFCOI_03249	4.58e-140	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
KGFKFCOI_03250	7.19e-298	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KGFKFCOI_03251	3.55e-146	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KGFKFCOI_03252	1.2e-282	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KGFKFCOI_03253	2.68e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
KGFKFCOI_03254	3.44e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KGFKFCOI_03255	1.44e-206	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
KGFKFCOI_03256	2.24e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KGFKFCOI_03257	3.78e-219	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KGFKFCOI_03258	3.6e-64	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
KGFKFCOI_03260	3.48e-205	yvlB	-	-	S	-	-	-	Putative adhesin
KGFKFCOI_03261	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KGFKFCOI_03262	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KGFKFCOI_03263	2.02e-220	yoaV3	-	-	EG	-	-	-	EamA-like transporter family
KGFKFCOI_03264	9.16e-265	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGFKFCOI_03265	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
KGFKFCOI_03266	3.78e-178	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
KGFKFCOI_03267	7.66e-195	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KGFKFCOI_03268	7.42e-161	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
KGFKFCOI_03269	8.63e-194	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
KGFKFCOI_03270	1.24e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KGFKFCOI_03271	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGFKFCOI_03272	3.01e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KGFKFCOI_03273	6.79e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	cold-shock protein
KGFKFCOI_03274	7.77e-198	-	-	-	-	-	-	-	-
KGFKFCOI_03276	4.42e-87	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
KGFKFCOI_03277	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KGFKFCOI_03278	3.19e-66	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
KGFKFCOI_03279	1.67e-46	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KGFKFCOI_03280	2.99e-103	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KGFKFCOI_03281	4.08e-247	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
KGFKFCOI_03282	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
KGFKFCOI_03283	1.12e-07	yvyG	-	-	NOU	-	-	-	Flagellar biosynthesis protein FlgN
KGFKFCOI_03284	6.14e-53	-	-	-	N	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Anti-sigma-28 factor, FlgM
KGFKFCOI_03285	5.44e-99	yvyF	-	-	S	-	-	-	flagellar protein
KGFKFCOI_03286	2.06e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
KGFKFCOI_03287	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KGFKFCOI_03288	1.34e-197	degV	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03289	4.63e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFKFCOI_03290	6.87e-257	degS	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KGFKFCOI_03291	1.99e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
KGFKFCOI_03292	7.57e-141	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KGFKFCOI_03293	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
KGFKFCOI_03294	8.72e-203	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
KGFKFCOI_03295	4.99e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_03296	5.46e-192	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_03297	2.28e-248	oppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_03298	2.96e-105	-	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
KGFKFCOI_03299	4.43e-251	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03300	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGFKFCOI_03301	1.2e-207	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KGFKFCOI_03302	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KGFKFCOI_03303	0.0	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KGFKFCOI_03304	7.06e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
KGFKFCOI_03305	1.68e-176	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
KGFKFCOI_03306	4.63e-299	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KGFKFCOI_03307	0.0	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KGFKFCOI_03308	2.9e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KGFKFCOI_03309	2.39e-179	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KGFKFCOI_03310	2.08e-85	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
KGFKFCOI_03311	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGFKFCOI_03312	1.08e-246	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGFKFCOI_03313	8.45e-147	ymaB	-	-	S	-	-	-	MutT family
KGFKFCOI_03314	1.82e-130	pncA	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
KGFKFCOI_03315	2.24e-37	-	-	-	-	-	-	-	-
KGFKFCOI_03316	9.52e-285	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
KGFKFCOI_03317	4.11e-173	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_03318	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KGFKFCOI_03319	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	invertase
KGFKFCOI_03320	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03321	9.9e-208	lplC7	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
KGFKFCOI_03322	1.43e-225	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
KGFKFCOI_03324	3.43e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
KGFKFCOI_03326	1.6e-150	-	-	-	-	-	-	-	-
KGFKFCOI_03327	7.22e-262	-	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_03328	2.15e-204	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03329	4.55e-211	-	-	-	G	ko:K02025,ko:K17238	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03330	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03331	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
KGFKFCOI_03332	6.15e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
KGFKFCOI_03333	1.85e-204	-	-	-	S	-	-	-	NYN domain
KGFKFCOI_03334	1.99e-175	-	-	-	-	-	-	-	-
KGFKFCOI_03336	7.5e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
KGFKFCOI_03337	8.03e-160	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03338	3.25e-185	-	-	-	-	-	-	-	-
KGFKFCOI_03340	1.39e-142	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
KGFKFCOI_03341	9.84e-181	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
KGFKFCOI_03342	2.08e-112	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03343	6.92e-193	yrzF	-	-	KLT	-	-	-	serine threonine protein kinase
KGFKFCOI_03344	1.59e-53	-	-	-	-	-	-	-	-
KGFKFCOI_03345	1.8e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_03346	1.1e-152	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFKFCOI_03348	2.09e-243	-	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KGFKFCOI_03349	3.14e-166	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_03350	2.2e-134	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
KGFKFCOI_03351	8.87e-215	yobV	-	-	K	-	-	-	WYL domain
KGFKFCOI_03352	2.65e-118	dinB	-	-	S	-	-	-	DinB family
KGFKFCOI_03353	3.58e-198	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
KGFKFCOI_03354	1.74e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGFKFCOI_03355	8.92e-273	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_03356	1.56e-228	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KGFKFCOI_03357	1.06e-151	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
KGFKFCOI_03358	2.5e-126	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KGFKFCOI_03359	6.63e-55	-	-	-	-	-	-	-	-
KGFKFCOI_03363	0.0	-	-	-	UW	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
KGFKFCOI_03369	7.72e-229	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_03370	3.13e-236	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KGFKFCOI_03371	6.65e-183	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
KGFKFCOI_03372	2.96e-91	-	-	-	-	-	-	-	-
KGFKFCOI_03373	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGFKFCOI_03374	8.96e-317	-	-	-	M	-	-	-	-O-antigen
KGFKFCOI_03375	8.35e-73	-	-	-	-	-	-	-	-
KGFKFCOI_03376	8.43e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
KGFKFCOI_03377	2.62e-197	-	-	-	S	-	-	-	Glycosyl transferase family 2
KGFKFCOI_03378	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
KGFKFCOI_03379	9.45e-152	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03380	1.07e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, C-terminal domain
KGFKFCOI_03381	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
KGFKFCOI_03382	8.99e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
KGFKFCOI_03383	2.32e-61	-	-	-	L	-	-	-	Transposase IS200 like
KGFKFCOI_03384	1.55e-314	-	-	-	S	ko:K12940	-	ko00000,ko01002	Peptidase dimerisation domain
KGFKFCOI_03385	0.0	-	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
KGFKFCOI_03386	0.0	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
KGFKFCOI_03387	5.38e-309	-	-	-	KT	-	-	-	transcriptional regulatory protein
KGFKFCOI_03388	5.49e-193	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
KGFKFCOI_03389	2.37e-271	thrCA	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
KGFKFCOI_03390	2.31e-116	-	-	-	M	ko:K01993	-	ko00000	PFAM secretion protein HlyD family protein
KGFKFCOI_03391	1.69e-184	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_03392	1.27e-254	ybhR	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
KGFKFCOI_03393	1.33e-152	ycfA	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03394	1.56e-137	ywqN_1	-	-	S	-	-	-	NAD(P)H-dependent
KGFKFCOI_03395	7.56e-209	-	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_03396	1.26e-10	tlp	-	-	S	ko:K06434	-	ko00000	spore protein
KGFKFCOI_03399	1.04e-110	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
KGFKFCOI_03400	2.46e-114	-	-	-	-	-	-	-	-
KGFKFCOI_03401	3.57e-202	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
KGFKFCOI_03402	9.17e-100	fruD	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGFKFCOI_03403	0.0	fruC	2.7.1.202	-	G	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGFKFCOI_03404	3.94e-221	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
KGFKFCOI_03405	6.56e-182	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGFKFCOI_03406	1.31e-212	XK27_03180	-	-	T	-	-	-	Belongs to the universal stress protein A family
KGFKFCOI_03408	2.59e-69	-	-	-	-	-	-	-	-
KGFKFCOI_03409	1.49e-74	-	-	-	-	-	-	-	-
KGFKFCOI_03410	3.13e-253	-	-	-	E	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
KGFKFCOI_03411	7.4e-226	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
KGFKFCOI_03412	7.59e-180	-	-	-	E	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
KGFKFCOI_03413	2.09e-172	potC3	-	-	P	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03414	9.33e-252	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KGFKFCOI_03415	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
KGFKFCOI_03416	0.0	M1-554	-	-	G	-	-	-	Endonuclease Exonuclease Phosphatase
KGFKFCOI_03417	2.39e-18	-	-	-	S	-	-	-	Inner spore coat protein D
KGFKFCOI_03418	2.08e-81	-	-	-	FJ	-	-	-	tRNA wobble adenosine to inosine editing
KGFKFCOI_03419	1.57e-201	-	-	-	P	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
KGFKFCOI_03420	2.52e-206	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03421	2.46e-310	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
KGFKFCOI_03422	1.41e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGFKFCOI_03423	0.0	ltaS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
KGFKFCOI_03424	4.63e-175	lacR	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
KGFKFCOI_03425	1.53e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGFKFCOI_03426	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KGFKFCOI_03427	9.24e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KGFKFCOI_03428	1.57e-187	-	-	-	C	-	-	-	lyase activity
KGFKFCOI_03429	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
KGFKFCOI_03430	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
KGFKFCOI_03431	8.9e-216	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
KGFKFCOI_03432	1.07e-65	-	-	-	-	-	-	-	-
KGFKFCOI_03433	3.63e-172	yvcP	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_03434	3.93e-248	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
KGFKFCOI_03435	6.61e-183	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03436	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
KGFKFCOI_03438	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KGFKFCOI_03439	9.9e-208	-	-	-	S	-	-	-	CAAX amino terminal protease family protein
KGFKFCOI_03440	2.66e-220	-	-	-	K	-	-	-	Putative sugar-binding domain
KGFKFCOI_03441	5.44e-79	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KGFKFCOI_03442	1.29e-235	-	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
KGFKFCOI_03443	8.78e-115	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
KGFKFCOI_03444	1.9e-89	-	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
KGFKFCOI_03445	1.07e-300	-	-	-	E	-	-	-	SAF
KGFKFCOI_03446	2.05e-51	-	-	-	G	-	-	-	PTS HPr component phosphorylation site
KGFKFCOI_03447	1.95e-158	-	-	-	-	-	-	-	-
KGFKFCOI_03448	4.23e-123	-	-	-	S	-	-	-	VanZ like family
KGFKFCOI_03449	2.44e-104	yybA	-	-	K	-	-	-	transcriptional
KGFKFCOI_03450	5.94e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_03451	1.88e-225	ssuA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KGFKFCOI_03452	2.49e-134	ssuC_2	-	-	P	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03453	1.99e-199	ssuB	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KGFKFCOI_03454	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
KGFKFCOI_03455	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
KGFKFCOI_03456	2.08e-265	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
KGFKFCOI_03457	7.19e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
KGFKFCOI_03458	1.37e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KGFKFCOI_03460	5.71e-261	-	-	-	S	-	-	-	Tetratricopeptide repeat
KGFKFCOI_03461	1.46e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KGFKFCOI_03463	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KGFKFCOI_03464	7.6e-118	-	-	-	-	-	-	-	-
KGFKFCOI_03465	7.7e-165	-	-	-	S	-	-	-	KR domain
KGFKFCOI_03466	9.44e-190	M1-276	-	-	-	-	-	-	-
KGFKFCOI_03467	6.04e-272	ysh1	-	-	J	-	-	-	Metallo-beta-lactamase superfamily
KGFKFCOI_03468	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03469	8.22e-246	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03470	1.2e-234	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KGFKFCOI_03471	1.71e-207	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03472	9.05e-160	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KGFKFCOI_03473	4.2e-79	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
KGFKFCOI_03474	4.22e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_03476	4.04e-211	-	-	-	EG	-	-	-	EamA-like transporter family
KGFKFCOI_03477	0.0	ywoF	-	-	P	-	-	-	Right handed beta helix region
KGFKFCOI_03478	9.48e-125	mutT	3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574	ko00230,map00230	ko00000,ko00001,ko01000,ko03400	nUDIX hydrolase
KGFKFCOI_03479	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
KGFKFCOI_03481	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
KGFKFCOI_03482	2.21e-192	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03483	3.74e-211	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03484	1.89e-278	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
KGFKFCOI_03485	2.47e-220	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_03486	1.42e-291	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_03487	6.01e-270	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_03488	7.62e-133	-	-	-	K	-	-	-	AraC-like ligand binding domain
KGFKFCOI_03489	8.08e-185	inoDHR	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_03490	4.18e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03491	3.93e-220	ugpA7	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03492	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
KGFKFCOI_03493	2.45e-268	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_03494	5.46e-181	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KGFKFCOI_03495	8.28e-222	-	-	-	K	-	-	-	Cupin domain
KGFKFCOI_03496	2.02e-247	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_03497	6.43e-88	-	-	-	S	-	-	-	Protein of unknown function, DUF393
KGFKFCOI_03498	5.97e-209	yfhB	-	-	S	-	-	-	PhzF family
KGFKFCOI_03499	2.26e-101	-	-	-	V	-	-	-	Beta-lactamase
KGFKFCOI_03500	2.12e-120	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGFKFCOI_03501	0.0	-	-	-	E	-	-	-	Aminotransferase class-V
KGFKFCOI_03502	0.0	-	-	-	M	-	-	-	Sulfatase
KGFKFCOI_03503	3.39e-91	-	-	-	E	ko:K07032	-	ko00000	lactoylglutathione lyase activity
KGFKFCOI_03504	1.71e-202	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
KGFKFCOI_03506	3.37e-220	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
KGFKFCOI_03507	1.19e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KGFKFCOI_03508	1.2e-57	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
KGFKFCOI_03509	3.03e-190	araQ	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
KGFKFCOI_03510	2.95e-206	-	-	-	G	ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03511	5.42e-312	-	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_03512	2.72e-67	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
KGFKFCOI_03513	5.38e-154	-	-	-	E	-	-	-	AzlC protein
KGFKFCOI_03514	4.71e-129	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_03515	1.21e-120	M1-753	-	-	M	-	-	-	FR47-like protein
KGFKFCOI_03516	4.68e-188	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase domain
KGFKFCOI_03518	5.27e-49	ydaS	-	-	S	-	-	-	membrane
KGFKFCOI_03519	1.01e-123	ywmF	-	-	S	-	-	-	Peptidase M50
KGFKFCOI_03520	1.32e-309	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KGFKFCOI_03521	2.15e-153	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
KGFKFCOI_03522	2.53e-38	-	-	-	-	-	-	-	-
KGFKFCOI_03523	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
KGFKFCOI_03524	1.07e-263	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
KGFKFCOI_03525	6.62e-280	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
KGFKFCOI_03526	1.11e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_03527	7.14e-187	-	-	-	K	-	-	-	acetyltransferase
KGFKFCOI_03528	1.58e-111	-	-	-	S	ko:K06385	-	ko00000	Stage II sporulation protein P (SpoIIP)
KGFKFCOI_03529	1.42e-211	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein kinase domain
KGFKFCOI_03530	1.68e-76	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
KGFKFCOI_03531	1.02e-235	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGFKFCOI_03532	2.02e-138	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
KGFKFCOI_03533	5.49e-124	-	-	-	-	-	-	-	-
KGFKFCOI_03535	3.04e-233	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KGFKFCOI_03536	1.18e-309	-	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03537	0.0	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
KGFKFCOI_03538	7e-293	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KGFKFCOI_03539	0.0	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
KGFKFCOI_03540	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KGFKFCOI_03541	0.0	-	-	-	T	-	-	-	COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
KGFKFCOI_03542	6.94e-282	-	-	-	G	-	-	-	Transmembrane secretion effector
KGFKFCOI_03543	6.58e-254	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_03544	1.71e-138	desR	-	-	K	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
KGFKFCOI_03545	2.32e-153	-	-	-	-	-	-	-	-
KGFKFCOI_03546	3.87e-200	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
KGFKFCOI_03547	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KGFKFCOI_03548	4.45e-225	-	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
KGFKFCOI_03549	4.27e-132	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
KGFKFCOI_03550	9.05e-93	-	-	-	-	-	-	-	-
KGFKFCOI_03551	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
KGFKFCOI_03552	8.52e-269	gatD	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
KGFKFCOI_03553	4.01e-30	-	-	-	-	-	-	-	-
KGFKFCOI_03554	7.98e-253	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KGFKFCOI_03555	7.32e-288	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
KGFKFCOI_03556	3.67e-57	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGFKFCOI_03557	2.34e-105	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGFKFCOI_03558	0.0	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
KGFKFCOI_03559	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
KGFKFCOI_03560	1.97e-255	-	-	-	-	-	-	-	-
KGFKFCOI_03561	7.47e-141	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
KGFKFCOI_03562	1.01e-226	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
KGFKFCOI_03563	2.26e-145	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KGFKFCOI_03564	7.67e-124	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
KGFKFCOI_03565	9.7e-265	siaT_3	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
KGFKFCOI_03566	9.62e-111	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_03567	6.9e-234	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_03568	1.52e-237	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
KGFKFCOI_03569	4.89e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
KGFKFCOI_03570	1.38e-97	-	-	-	-	-	-	-	-
KGFKFCOI_03571	8.2e-104	-	-	-	-	-	-	-	-
KGFKFCOI_03572	5.89e-257	ysdC_3	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	M42 glutamyl aminopeptidase
KGFKFCOI_03573	7.46e-59	M1-485	-	-	S	-	-	-	Membrane
KGFKFCOI_03574	2.07e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
KGFKFCOI_03575	6.17e-241	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KGFKFCOI_03576	6.61e-187	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
KGFKFCOI_03577	6.64e-189	-	-	-	S	ko:K06976	-	ko00000	GNAT acetyltransferase
KGFKFCOI_03578	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
KGFKFCOI_03579	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
KGFKFCOI_03580	1.97e-35	-	-	-	-	-	-	-	-
KGFKFCOI_03581	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
KGFKFCOI_03582	8.04e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
KGFKFCOI_03583	8.92e-144	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
KGFKFCOI_03584	9.41e-140	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFKFCOI_03585	4.22e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_03586	7.66e-163	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
KGFKFCOI_03587	1.67e-135	-	-	-	-	-	-	-	-
KGFKFCOI_03588	2.51e-06	liaI	-	-	-	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	-
KGFKFCOI_03589	6.65e-51	-	-	-	-	-	-	-	-
KGFKFCOI_03590	7.35e-152	-	-	-	S	-	-	-	Cupin
KGFKFCOI_03591	0.0	-	-	-	M	-	-	-	glycoside hydrolase family 81
KGFKFCOI_03592	7.61e-247	cytR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KGFKFCOI_03593	3.83e-165	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KGFKFCOI_03594	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KGFKFCOI_03595	7.97e-222	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_03596	1.1e-228	-	-	-	K	-	-	-	WYL domain
KGFKFCOI_03597	4.55e-150	-	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KGFKFCOI_03598	1.5e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGFKFCOI_03599	6.1e-203	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
KGFKFCOI_03600	8.37e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
KGFKFCOI_03601	5.77e-214	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_03602	0.0	gdhA	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KGFKFCOI_03603	6.85e-179	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KGFKFCOI_03604	6.33e-227	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_03605	6.88e-261	-	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
KGFKFCOI_03606	1.61e-177	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KGFKFCOI_03607	6.41e-77	-	-	-	S	-	-	-	Dinitrogenase iron-molybdenum cofactor
KGFKFCOI_03608	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFKFCOI_03609	2.12e-120	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
KGFKFCOI_03610	2.25e-210	ytlI3	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
KGFKFCOI_03611	2.44e-112	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KGFKFCOI_03612	8.04e-158	-	-	-	S	-	-	-	membrane
KGFKFCOI_03613	1.03e-37	-	-	-	S	-	-	-	spore protein
KGFKFCOI_03614	3.08e-39	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
KGFKFCOI_03615	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KGFKFCOI_03617	7.78e-202	yerO	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03618	1.38e-165	-	-	-	-	-	-	-	-
KGFKFCOI_03619	1.31e-210	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KGFKFCOI_03620	8.89e-80	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
KGFKFCOI_03621	1.16e-147	-	-	-	Q	-	-	-	Methyltransferase domain
KGFKFCOI_03622	1.01e-186	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
KGFKFCOI_03623	2.54e-10	-	-	-	-	-	-	-	-
KGFKFCOI_03624	2.52e-286	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KGFKFCOI_03625	1.48e-217	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
KGFKFCOI_03626	8.3e-223	-	-	-	P	ko:K07217	-	ko00000	Catalase
KGFKFCOI_03627	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2254)
KGFKFCOI_03628	1.31e-211	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycine betaine ABC transporter
KGFKFCOI_03629	2.75e-306	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
KGFKFCOI_03630	2.06e-184	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KGFKFCOI_03631	1.27e-174	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03632	1.16e-217	fhuB11	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03633	4.04e-210	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_03634	0.0	-	-	-	M	-	-	-	Cell surface protein
KGFKFCOI_03635	1.38e-156	isdC	-	-	M	-	-	-	NEAr Transporter domain
KGFKFCOI_03636	2.94e-71	isdG	1.14.99.48	-	C	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
KGFKFCOI_03637	1.21e-223	fhuG7	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03638	6.28e-221	fhuD11	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KGFKFCOI_03639	1.52e-286	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KGFKFCOI_03640	1.35e-192	-	-	-	S	-	-	-	Methyltransferase domain
KGFKFCOI_03641	1.52e-144	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
KGFKFCOI_03642	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
KGFKFCOI_03643	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
KGFKFCOI_03644	2.6e-296	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
KGFKFCOI_03645	5.26e-163	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KGFKFCOI_03646	4.88e-200	gltR3	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_03647	2.06e-233	-	3.8.1.3	-	S	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
KGFKFCOI_03648	2.73e-201	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
KGFKFCOI_03649	2.85e-242	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KGFKFCOI_03650	1.36e-242	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_03651	1.57e-189	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03652	2.55e-219	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03653	4.41e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03654	5.15e-289	-	-	-	GK	-	-	-	ROK family
KGFKFCOI_03655	2.73e-283	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
KGFKFCOI_03656	1.1e-86	yqiX	-	-	S	-	-	-	YolD-like protein
KGFKFCOI_03658	3.02e-06	sda	-	-	S	ko:K06371	-	ko00000	sporulation
KGFKFCOI_03659	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
KGFKFCOI_03660	4.55e-64	-	-	-	-	-	-	-	-
KGFKFCOI_03661	3.14e-113	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
KGFKFCOI_03662	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KGFKFCOI_03663	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase
KGFKFCOI_03664	8.28e-255	dctP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGFKFCOI_03665	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_03666	9.91e-222	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
KGFKFCOI_03667	1.1e-228	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KGFKFCOI_03668	2.63e-161	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
KGFKFCOI_03671	9.21e-212	-	-	-	V	-	-	-	VanW like protein
KGFKFCOI_03672	1.99e-124	-	-	-	V	-	-	-	(ABC) transporter
KGFKFCOI_03673	2.06e-61	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
KGFKFCOI_03674	6.33e-157	yqeB	-	-	-	-	-	-	-
KGFKFCOI_03675	2.97e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KGFKFCOI_03676	1.1e-196	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KGFKFCOI_03677	0.0	-	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGFKFCOI_03678	5.31e-115	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
KGFKFCOI_03679	4.27e-33	-	-	-	-	-	-	-	-
KGFKFCOI_03680	3.04e-80	-	-	-	-	-	-	-	-
KGFKFCOI_03681	3.76e-142	-	-	-	K	ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KGFKFCOI_03683	3.93e-199	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KGFKFCOI_03684	5.35e-247	-	-	-	G	-	-	-	Xylose isomerase
KGFKFCOI_03685	4.1e-186	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03686	1.36e-217	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03687	1.11e-301	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03688	5.72e-238	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KGFKFCOI_03689	4.74e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
KGFKFCOI_03690	1.32e-80	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
KGFKFCOI_03691	4.33e-189	-	-	-	K	-	-	-	Helix-turn-helix domain
KGFKFCOI_03692	2.14e-232	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KGFKFCOI_03693	9.12e-199	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
KGFKFCOI_03694	1.07e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KGFKFCOI_03695	2.7e-312	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
KGFKFCOI_03696	1.92e-196	-	-	-	S	-	-	-	Nucleotidyltransferase domain
KGFKFCOI_03697	7e-196	-	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
KGFKFCOI_03698	1.15e-163	-	-	-	KT	-	-	-	Forkhead associated domain
KGFKFCOI_03699	7.13e-313	amaB_2	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KGFKFCOI_03700	3.08e-204	yuiI	-	-	S	ko:K07017	-	ko00000	Putative esterase
KGFKFCOI_03701	1.58e-238	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03702	8.75e-237	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03703	1.37e-224	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
KGFKFCOI_03704	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
KGFKFCOI_03706	1.5e-230	ectD	1.14.11.55	-	Q	ko:K10674	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Phytanoyl-CoA dioxygenase (PhyH)
KGFKFCOI_03707	9.05e-258	-	-	-	-	-	-	-	-
KGFKFCOI_03708	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
KGFKFCOI_03709	5.78e-247	gerKB	-	-	E	-	-	-	Spore germination protein
KGFKFCOI_03710	4.21e-266	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
KGFKFCOI_03711	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
KGFKFCOI_03712	4.47e-177	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03713	1.68e-301	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03714	6.74e-16	amyD1	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03715	1.81e-156	msmF3	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03716	4.27e-186	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
KGFKFCOI_03717	0.0	-	-	-	S	-	-	-	Chlorophyllase enzyme
KGFKFCOI_03718	9.41e-84	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGFKFCOI_03720	0.0	-	-	-	GKT	-	-	-	Mga helix-turn-helix domain
KGFKFCOI_03721	5.91e-235	-	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KGFKFCOI_03722	2.25e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
KGFKFCOI_03723	4.42e-274	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
KGFKFCOI_03724	3.3e-200	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
KGFKFCOI_03725	7.71e-133	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
KGFKFCOI_03726	3.01e-09	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
KGFKFCOI_03727	4.04e-204	-	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylases
KGFKFCOI_03728	6.41e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
KGFKFCOI_03729	8.65e-92	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_03730	1.83e-257	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
KGFKFCOI_03731	4.56e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
KGFKFCOI_03732	1.99e-131	-	-	-	S	-	-	-	DinB superfamily
KGFKFCOI_03734	1.27e-33	rapA	-	-	S	ko:K06359,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03735	9.06e-189	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03736	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
KGFKFCOI_03737	8.44e-307	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
KGFKFCOI_03738	3.52e-191	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
KGFKFCOI_03739	1.92e-316	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
KGFKFCOI_03740	7.26e-304	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
KGFKFCOI_03741	1.58e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_03742	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_03743	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_03744	2.68e-129	-	-	-	-	-	-	-	-
KGFKFCOI_03745	4.31e-198	yxxF	-	-	EG	-	-	-	EamA-like transporter family
KGFKFCOI_03746	4.15e-191	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03747	5.17e-142	-	-	-	S	-	-	-	ABC-2 family transporter protein
KGFKFCOI_03748	2.51e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_03749	5.49e-237	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_03750	5.72e-241	-	-	-	E	-	-	-	Amidinotransferase
KGFKFCOI_03751	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
KGFKFCOI_03752	2.05e-176	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_03753	5.64e-254	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
KGFKFCOI_03754	5.86e-297	-	-	-	S	-	-	-	Erythromycin esterase
KGFKFCOI_03755	6.03e-119	ykuD	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_03756	7.66e-233	-	-	-	S	-	-	-	Choline/ethanolamine kinase
KGFKFCOI_03757	6.66e-72	-	-	-	-	-	-	-	-
KGFKFCOI_03758	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_03759	1.29e-152	-	-	-	-	-	-	-	-
KGFKFCOI_03760	9.96e-82	-	-	-	K	-	-	-	MerR, DNA binding
KGFKFCOI_03761	1.15e-197	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_03762	5.16e-95	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03763	3.73e-104	-	-	-	-	-	-	-	-
KGFKFCOI_03764	7.19e-209	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
KGFKFCOI_03765	1.62e-206	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KGFKFCOI_03766	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KGFKFCOI_03767	3.97e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KGFKFCOI_03768	9.82e-202	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGFKFCOI_03769	6.64e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
KGFKFCOI_03770	4.15e-231	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
KGFKFCOI_03772	3.53e-119	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
KGFKFCOI_03773	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KGFKFCOI_03774	1.63e-161	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
KGFKFCOI_03775	1.32e-171	-	-	-	-	-	-	-	-
KGFKFCOI_03776	4.24e-182	-	-	-	S	-	-	-	ABC-2 family transporter protein
KGFKFCOI_03777	2.21e-167	pstB13	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
KGFKFCOI_03778	4.78e-135	-	-	-	H	-	-	-	Flavoprotein
KGFKFCOI_03779	0.0	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
KGFKFCOI_03780	0.0	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
KGFKFCOI_03782	1.43e-222	XK27_06795	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
KGFKFCOI_03783	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KGFKFCOI_03786	1.04e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KGFKFCOI_03787	7.57e-135	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KGFKFCOI_03788	0.0	-	-	-	M	-	-	-	cell wall anchor domain
KGFKFCOI_03790	1.25e-202	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
KGFKFCOI_03791	2.03e-251	-	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
KGFKFCOI_03792	1.44e-311	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
KGFKFCOI_03793	6.76e-56	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
KGFKFCOI_03794	2.78e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KGFKFCOI_03795	2.05e-183	-	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
KGFKFCOI_03796	2.22e-229	lacC	2.7.1.144	-	G	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
KGFKFCOI_03797	1.06e-118	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
KGFKFCOI_03799	1.68e-108	-	-	-	-	-	-	-	-
KGFKFCOI_03800	2.67e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
KGFKFCOI_03801	9.06e-182	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
KGFKFCOI_03802	0.0	malP	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_03803	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGFKFCOI_03804	0.0	-	-	-	C	-	-	-	FAD dependent oxidoreductase
KGFKFCOI_03805	9.39e-192	ugpE3	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03806	4.25e-220	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03807	3.95e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03808	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_03809	7.72e-177	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
KGFKFCOI_03810	1.75e-313	-	-	-	G	-	-	-	beta-fructofuranosidase activity
KGFKFCOI_03811	1.79e-121	-	-	-	G	-	-	-	beta-fructofuranosidase activity
KGFKFCOI_03812	1.64e-98	-	-	-	L	ko:K07451,ko:K07452	-	ko00000,ko01000,ko02048	HNH endonuclease
KGFKFCOI_03813	2.19e-61	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFKFCOI_03814	2.37e-250	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFKFCOI_03815	1.13e-152	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	RecB family exonuclease
KGFKFCOI_03816	1.3e-202	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
KGFKFCOI_03817	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
KGFKFCOI_03818	1.7e-178	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
KGFKFCOI_03820	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Metal dependent phosphohydrolases with conserved 'HD' motif.
KGFKFCOI_03821	4e-163	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KGFKFCOI_03822	0.0	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
KGFKFCOI_03824	1.1e-103	-	-	-	S	-	-	-	yiaA/B two helix domain
KGFKFCOI_03825	6.62e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
KGFKFCOI_03826	1.7e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGFKFCOI_03827	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
KGFKFCOI_03829	3.15e-229	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
KGFKFCOI_03830	2.45e-215	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
KGFKFCOI_03831	1.01e-227	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
KGFKFCOI_03832	5.28e-146	-	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
KGFKFCOI_03833	9.55e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
KGFKFCOI_03834	6.17e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
KGFKFCOI_03835	1.08e-172	-	-	-	K	-	-	-	DeoR C terminal sensor domain
KGFKFCOI_03836	6.8e-175	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KGFKFCOI_03837	2.87e-272	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
KGFKFCOI_03838	6.73e-305	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
KGFKFCOI_03839	9.62e-75	-	-	-	S	ko:K07068	-	ko00000	DUF35 OB-fold domain, acyl-CoA-associated
KGFKFCOI_03840	2.53e-265	-	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Thiolase, C-terminal domain
KGFKFCOI_03841	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KGFKFCOI_03842	2.25e-118	-	-	-	S	-	-	-	DNA-binding protein with PD1-like DNA-binding motif
KGFKFCOI_03843	1.1e-179	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KGFKFCOI_03844	9.26e-278	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
KGFKFCOI_03845	2.82e-111	-	-	-	G	ko:K11689	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_03846	4.24e-247	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KGFKFCOI_03847	5.17e-174	-	-	-	K	ko:K19333	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_03848	1.7e-261	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03851	8.98e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
KGFKFCOI_03852	5.85e-225	-	-	-	P	ko:K07217	-	ko00000	Catalase
KGFKFCOI_03853	1.88e-222	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
KGFKFCOI_03854	9.66e-38	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
KGFKFCOI_03855	0.0	-	-	-	F	-	-	-	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
KGFKFCOI_03856	2.17e-78	ydeP9	-	-	K	-	-	-	HxlR-like helix-turn-helix
KGFKFCOI_03857	5.8e-216	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
KGFKFCOI_03858	1.52e-205	ycnC	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03859	8.7e-278	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
KGFKFCOI_03861	4.75e-96	-	-	-	-	-	-	-	-
KGFKFCOI_03864	1.42e-47	-	-	-	-	-	-	-	-
KGFKFCOI_03865	3.95e-155	-	-	-	S	-	-	-	Putative adhesin
KGFKFCOI_03866	3.38e-159	-	-	-	S	-	-	-	ABC-2 family transporter protein
KGFKFCOI_03867	3.21e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_03868	1.76e-172	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_03869	4.18e-261	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_03870	1.83e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGFKFCOI_03871	2.69e-168	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
KGFKFCOI_03872	1.03e-262	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03873	1.68e-177	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
KGFKFCOI_03874	0.0	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_03875	0.0	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03876	9.76e-256	fbpC	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KGFKFCOI_03877	6.74e-244	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_03879	1.85e-115	-	-	-	-	-	-	-	-
KGFKFCOI_03880	1.8e-290	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KGFKFCOI_03881	4.58e-289	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
KGFKFCOI_03882	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KGFKFCOI_03883	1.48e-288	-	-	-	E	-	-	-	Peptidase family M28
KGFKFCOI_03884	1.42e-247	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_03885	1.3e-236	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_03886	1.12e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
KGFKFCOI_03887	1.5e-202	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03888	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KGFKFCOI_03890	2.18e-213	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03891	7.35e-209	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
KGFKFCOI_03892	1.47e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KGFKFCOI_03893	2.88e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KGFKFCOI_03894	2.68e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KGFKFCOI_03895	5e-292	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGFKFCOI_03896	2.22e-61	-	-	-	-	-	-	-	-
KGFKFCOI_03897	0.0	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KGFKFCOI_03898	2.15e-75	-	-	-	-	-	-	-	-
KGFKFCOI_03899	3.93e-181	-	-	-	S	-	-	-	CAAX protease self-immunity
KGFKFCOI_03900	2.28e-113	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
KGFKFCOI_03901	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
KGFKFCOI_03905	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
KGFKFCOI_03908	2.13e-92	ytcD	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03909	2.78e-136	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KGFKFCOI_03910	1.71e-144	-	-	-	K	-	-	-	intracellular protease amidase
KGFKFCOI_03912	9.32e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
KGFKFCOI_03913	6.34e-315	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGFKFCOI_03914	7.2e-282	cps1C	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KGFKFCOI_03915	1.64e-203	spsK	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KGFKFCOI_03916	1.33e-254	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KGFKFCOI_03917	2.7e-132	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KGFKFCOI_03918	1.21e-214	rmlA2	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KGFKFCOI_03919	1.73e-139	-	-	-	M	-	-	-	Glycosyl transferase family 2
KGFKFCOI_03920	5.43e-228	-	-	-	M	-	-	-	Glycosyl transferase family 2
KGFKFCOI_03921	1.39e-190	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KGFKFCOI_03922	2.76e-289	-	-	-	-	-	-	-	-
KGFKFCOI_03923	1.75e-156	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
KGFKFCOI_03924	2.34e-209	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KGFKFCOI_03925	8.01e-201	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KGFKFCOI_03930	1.61e-254	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
KGFKFCOI_03931	1.04e-271	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
KGFKFCOI_03932	6.22e-245	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
KGFKFCOI_03933	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
KGFKFCOI_03934	3.4e-256	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
KGFKFCOI_03935	8.15e-136	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
KGFKFCOI_03936	2.05e-104	-	-	-	S	-	-	-	Bacterial PH domain
KGFKFCOI_03937	1.23e-172	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
KGFKFCOI_03938	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
KGFKFCOI_03939	1.83e-156	mdmC1	-	-	S	-	-	-	O-methyltransferase
KGFKFCOI_03940	1.04e-215	-	-	-	K	-	-	-	LysR substrate binding domain
KGFKFCOI_03941	2.76e-59	sdpR	-	-	K	-	-	-	transcriptional
KGFKFCOI_03942	2.82e-147	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KGFKFCOI_03943	3.09e-188	-	-	-	G	-	-	-	Phosphoenolpyruvate phosphomutase
KGFKFCOI_03945	1.36e-209	-	-	-	E	-	-	-	Glyoxalase-like domain
KGFKFCOI_03946	2.89e-237	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KGFKFCOI_03947	2.58e-178	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KGFKFCOI_03948	5.38e-167	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KGFKFCOI_03949	4.94e-29	-	-	-	-	-	-	-	-
KGFKFCOI_03951	7.25e-153	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
KGFKFCOI_03952	4.13e-109	-	-	-	K	ko:K13572	-	ko00000,ko03051	transcriptional regulator
KGFKFCOI_03953	9.17e-37	yobV9	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_03954	1.63e-195	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KGFKFCOI_03955	4.05e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_03956	3.05e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase family
KGFKFCOI_03957	6.19e-239	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
KGFKFCOI_03959	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
KGFKFCOI_03961	8.65e-296	-	-	-	S	-	-	-	Putative esterase
KGFKFCOI_03962	6.97e-121	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
KGFKFCOI_03963	5.47e-66	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
KGFKFCOI_03964	7.51e-188	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
KGFKFCOI_03966	3.56e-281	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
KGFKFCOI_03967	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KGFKFCOI_03968	0.0	-	-	-	S	-	-	-	Membrane
KGFKFCOI_03969	2.87e-78	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KGFKFCOI_03970	1.26e-235	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KGFKFCOI_03971	2.53e-118	-	-	-	S	-	-	-	OHCU decarboxylase
KGFKFCOI_03972	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
KGFKFCOI_03973	4.68e-300	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KGFKFCOI_03974	6.26e-311	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KGFKFCOI_03975	2.32e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KGFKFCOI_03976	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KGFKFCOI_03977	9.96e-213	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KGFKFCOI_03978	6.42e-140	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
KGFKFCOI_03979	2.73e-240	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KGFKFCOI_03980	9.89e-239	-	-	-	P	-	-	-	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KGFKFCOI_03981	9.24e-188	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03982	7.99e-182	-	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KGFKFCOI_03984	1.62e-241	-	-	-	P	-	-	-	NMT1-like family
KGFKFCOI_03985	1.49e-194	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_03986	2.39e-178	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KGFKFCOI_03987	0.0	fhuB5	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFKFCOI_03988	6.15e-235	cbrA5	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ferrichrome ABC transporter substrate-binding protein
KGFKFCOI_03989	3.34e-92	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
KGFKFCOI_03990	5.49e-107	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
KGFKFCOI_03991	1.07e-108	-	-	-	S	-	-	-	ASCH
KGFKFCOI_03992	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
KGFKFCOI_03993	1.76e-198	-	-	-	I	-	-	-	Domain of unknown function (DUF1932)
KGFKFCOI_03994	1.02e-200	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KGFKFCOI_03995	4.34e-151	-	4.1.3.17	-	H	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	ko00000,ko00001,ko01000	Methyltransferase
KGFKFCOI_03996	3.3e-43	-	-	-	-	-	-	-	-
KGFKFCOI_03997	6.08e-309	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
KGFKFCOI_03998	1.37e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFKFCOI_03999	5.68e-233	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_04000	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_04001	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KGFKFCOI_04002	5.48e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KGFKFCOI_04003	5.93e-149	ydgI	-	-	C	-	-	-	nitroreductase
KGFKFCOI_04004	6.26e-80	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_04005	2.19e-121	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KGFKFCOI_04006	4.65e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
KGFKFCOI_04007	6.75e-269	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
KGFKFCOI_04008	3.2e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
KGFKFCOI_04009	2.06e-177	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
KGFKFCOI_04010	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KGFKFCOI_04011	3.24e-221	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_04012	7.25e-206	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KGFKFCOI_04013	1.06e-180	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_04014	6.79e-59	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KGFKFCOI_04015	2.85e-304	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KGFKFCOI_04017	2.93e-108	-	-	-	-	-	-	-	-
KGFKFCOI_04018	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KGFKFCOI_04019	1.64e-300	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
KGFKFCOI_04020	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
KGFKFCOI_04022	1.64e-302	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KGFKFCOI_04023	0.0	-	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGFKFCOI_04024	3.71e-100	-	-	-	F	-	-	-	PFAM AIG2 family protein
KGFKFCOI_04025	2.41e-149	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
KGFKFCOI_04026	2.21e-94	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_04028	0.0	bglP11	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KGFKFCOI_04029	9.79e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
KGFKFCOI_04030	0.0	bglH7	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KGFKFCOI_04033	5.88e-94	-	-	-	L	-	-	-	transposase activity
KGFKFCOI_04034	1.7e-70	-	-	-	-	-	-	-	-
KGFKFCOI_04035	4.68e-99	-	-	-	S	-	-	-	Protein of unknown function, DUF600
KGFKFCOI_04036	5.61e-107	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
KGFKFCOI_04037	2.02e-50	-	-	-	-	-	-	-	-
KGFKFCOI_04038	3.09e-122	-	-	-	-	-	-	-	-
KGFKFCOI_04039	1.51e-99	-	-	-	S	-	-	-	Immunity protein 70
KGFKFCOI_04040	1.81e-167	-	-	-	U	-	-	-	Belongs to the WXG100 family
KGFKFCOI_04041	2.98e-80	-	-	-	-	-	-	-	-
KGFKFCOI_04042	2.07e-71	-	-	-	-	-	-	-	-
KGFKFCOI_04043	0.0	-	-	-	M	-	-	-	nuclease activity
KGFKFCOI_04044	2.83e-53	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
KGFKFCOI_04045	8.24e-44	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
KGFKFCOI_04048	1.41e-251	-	-	-	S	-	-	-	Tetratricopeptide repeat
KGFKFCOI_04049	0.0	-	-	-	T	-	-	-	Domain present in phytochromes and cGMP-specific phosphodiesterases.
KGFKFCOI_04050	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KGFKFCOI_04051	1.11e-202	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KGFKFCOI_04052	3.64e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
KGFKFCOI_04053	7.85e-96	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
KGFKFCOI_04054	1.06e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
KGFKFCOI_04055	3.66e-157	epsB	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
KGFKFCOI_04056	1.08e-150	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
KGFKFCOI_04057	2.99e-219	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KGFKFCOI_04058	1.17e-110	-	-	-	S	-	-	-	Tetratrico peptide repeat
KGFKFCOI_04059	1.1e-112	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
KGFKFCOI_04060	1.17e-104	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
KGFKFCOI_04061	7.07e-290	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KGFKFCOI_04062	6.27e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KGFKFCOI_04063	2.09e-216	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KGFKFCOI_04064	2.02e-61	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
KGFKFCOI_04065	1.56e-297	-	-	-	-	-	-	-	-
KGFKFCOI_04066	3.6e-306	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGFKFCOI_04067	2.71e-298	lytE	-	-	M	-	-	-	NlpC/P60 family
KGFKFCOI_04068	1.2e-195	-	-	-	Q	-	-	-	N-acetyltransferase
KGFKFCOI_04069	3.37e-115	yisT	-	-	S	-	-	-	DinB family
KGFKFCOI_04070	7.16e-127	-	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KGFKFCOI_04071	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
KGFKFCOI_04072	1.09e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KGFKFCOI_04073	3.57e-188	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
KGFKFCOI_04074	1.52e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KGFKFCOI_04075	1.27e-248	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
KGFKFCOI_04076	8.03e-256	-	-	-	E	-	-	-	Spore germination protein
KGFKFCOI_04077	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
KGFKFCOI_04078	4.62e-81	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
KGFKFCOI_04079	1.44e-183	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
KGFKFCOI_04080	2.58e-183	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
KGFKFCOI_04081	1.9e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
KGFKFCOI_04082	1.68e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
KGFKFCOI_04083	2.02e-63	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
KGFKFCOI_04084	1.25e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
KGFKFCOI_04085	1.07e-181	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
KGFKFCOI_04086	3.08e-243	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
KGFKFCOI_04087	1.92e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGFKFCOI_04088	1.66e-21	ywmB	-	-	S	-	-	-	TATA-box binding
KGFKFCOI_04089	2.09e-81	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KGFKFCOI_04090	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KGFKFCOI_04091	3.39e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KGFKFCOI_04092	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KGFKFCOI_04093	7.09e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGFKFCOI_04094	2.37e-47	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KGFKFCOI_04095	2.78e-28	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGFKFCOI_04096	3.41e-170	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KGFKFCOI_04097	1.25e-10	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
KGFKFCOI_04098	1.61e-44	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
KGFKFCOI_04099	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
KGFKFCOI_04100	1.1e-117	panZ	-	-	K	-	-	-	-acetyltransferase
KGFKFCOI_04101	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KGFKFCOI_04102	2.63e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KGFKFCOI_04103	2.79e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
KGFKFCOI_04104	3.9e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
KGFKFCOI_04105	2.49e-249	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
KGFKFCOI_04106	4.11e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGFKFCOI_04107	2.39e-121	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
KGFKFCOI_04108	6.43e-77	-	-	-	S	-	-	-	Regulator of ribonuclease activity B
KGFKFCOI_04109	9.76e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KGFKFCOI_04110	1.36e-96	ywlB	1.20.4.1, 2.3.1.1	-	E	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetyltransferase family. ArgA subfamily
KGFKFCOI_04111	7.81e-148	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
KGFKFCOI_04112	1.12e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KGFKFCOI_04113	1.55e-232	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KGFKFCOI_04114	0.0	cdr	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KGFKFCOI_04115	1.19e-97	-	-	-	-	-	-	-	-
KGFKFCOI_04116	1.88e-142	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KGFKFCOI_04117	2.08e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KGFKFCOI_04118	2.94e-300	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KGFKFCOI_04119	2.21e-228	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
KGFKFCOI_04120	2e-285	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGFKFCOI_04121	2.81e-149	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KGFKFCOI_04122	3.32e-206	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
KGFKFCOI_04123	1.27e-78	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
KGFKFCOI_04124	4.35e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
KGFKFCOI_04125	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KGFKFCOI_04126	6.82e-95	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KGFKFCOI_04127	1.83e-141	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_04128	1.15e-262	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
KGFKFCOI_04129	2.15e-200	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
KGFKFCOI_04130	2.8e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
KGFKFCOI_04131	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
KGFKFCOI_04132	8.2e-288	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KGFKFCOI_04133	6.53e-97	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
KGFKFCOI_04134	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KGFKFCOI_04135	1.89e-100	ywiB	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04136	2.02e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
KGFKFCOI_04137	8.83e-205	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KGFKFCOI_04138	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KGFKFCOI_04139	1.15e-199	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_04140	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KGFKFCOI_04141	5.84e-129	ywhD	-	-	S	-	-	-	YwhD family
KGFKFCOI_04142	1.39e-257	-	-	-	F	-	-	-	S-adenosylhomocysteine deaminase activity
KGFKFCOI_04143	5.89e-161	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
KGFKFCOI_04144	5.91e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
KGFKFCOI_04146	8.17e-119	ywgA	-	-	-	ko:K09388	-	ko00000	-
KGFKFCOI_04147	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
KGFKFCOI_04148	4.6e-273	gltP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGFKFCOI_04149	2.32e-195	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KGFKFCOI_04150	3.69e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
KGFKFCOI_04151	6.63e-184	-	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
KGFKFCOI_04152	1.35e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
KGFKFCOI_04153	2.12e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGFKFCOI_04154	3.16e-64	-	-	-	-	-	-	-	-
KGFKFCOI_04155	4.29e-252	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
KGFKFCOI_04156	5.34e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KGFKFCOI_04157	8.83e-209	natA1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_04158	2.28e-84	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KGFKFCOI_04159	1.01e-169	-	-	-	-	-	-	-	-
KGFKFCOI_04160	1.38e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
KGFKFCOI_04161	8.65e-107	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KGFKFCOI_04162	4.91e-78	ywdK	-	-	S	-	-	-	small membrane protein
KGFKFCOI_04163	1.31e-148	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFKFCOI_04164	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KGFKFCOI_04165	4.39e-62	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
KGFKFCOI_04166	5.7e-176	polC1	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
KGFKFCOI_04167	3.12e-223	-	-	-	T	ko:K07182	-	ko00000	Putative nucleotidyltransferase substrate binding domain
KGFKFCOI_04168	4.12e-296	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
KGFKFCOI_04169	2.18e-227	-	-	-	S	ko:K07120	-	ko00000	Pfam:AmoA
KGFKFCOI_04170	1.7e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KGFKFCOI_04171	7.47e-306	-	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04172	6.38e-191	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KGFKFCOI_04173	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
KGFKFCOI_04174	5.89e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
KGFKFCOI_04175	1.22e-161	-	-	-	E	-	-	-	AzlC protein
KGFKFCOI_04176	0.0	gntR9	-	-	K	-	-	-	Alanine-glyoxylate amino-transferase
KGFKFCOI_04177	7.44e-168	XK27_07210	-	-	S	-	-	-	B3/4 domain
KGFKFCOI_04178	4.32e-301	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	methionine gamma-lyase
KGFKFCOI_04179	1.12e-245	-	-	-	I	-	-	-	Fatty acid desaturase
KGFKFCOI_04180	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
KGFKFCOI_04181	2.3e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
KGFKFCOI_04182	1.56e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_04183	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGFKFCOI_04184	4.32e-105	bdbA	-	-	CO	-	-	-	Thioredoxin
KGFKFCOI_04185	5.29e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
KGFKFCOI_04186	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
KGFKFCOI_04188	5.89e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
KGFKFCOI_04189	2.44e-243	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
KGFKFCOI_04190	1.56e-175	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
KGFKFCOI_04191	4.21e-156	ydbC	-	-	G	-	-	-	Domain of unknown function (DUF4937
KGFKFCOI_04192	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
KGFKFCOI_04193	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGFKFCOI_04194	8.95e-293	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
KGFKFCOI_04195	2.81e-57	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
KGFKFCOI_04196	7.27e-73	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
KGFKFCOI_04197	2.48e-129	-	-	-	S	-	-	-	UPF0302 domain
KGFKFCOI_04198	2.37e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KGFKFCOI_04199	3.98e-205	XK27_03890	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KGFKFCOI_04200	4.85e-181	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KGFKFCOI_04201	4.61e-224	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KGFKFCOI_04202	8.38e-189	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
KGFKFCOI_04203	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
KGFKFCOI_04204	2.35e-290	-	-	-	S	-	-	-	Acetyltransferase
KGFKFCOI_04205	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
KGFKFCOI_04206	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KGFKFCOI_04207	7.42e-276	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
KGFKFCOI_04208	1.01e-132	-	-	-	S	-	-	-	DinB superfamily
KGFKFCOI_04209	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
KGFKFCOI_04210	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KGFKFCOI_04211	1.09e-221	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
KGFKFCOI_04212	5.49e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KGFKFCOI_04213	2.7e-147	yrbG	-	-	S	-	-	-	membrane
KGFKFCOI_04214	9.99e-216	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KGFKFCOI_04216	2.31e-182	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
KGFKFCOI_04217	7.71e-227	-	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
KGFKFCOI_04218	2.53e-139	-	-	-	K	-	-	-	GrpB protein
KGFKFCOI_04219	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGFKFCOI_04220	4.62e-85	yosT	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
KGFKFCOI_04221	4.69e-161	-	-	-	-	-	-	-	-
KGFKFCOI_04222	1.81e-161	-	-	-	-	-	-	-	-
KGFKFCOI_04223	1.6e-159	-	-	-	-	-	-	-	-
KGFKFCOI_04224	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_04225	1.19e-89	-	-	-	-	-	-	-	-
KGFKFCOI_04226	2.75e-91	-	-	-	-	-	-	-	-
KGFKFCOI_04227	3.3e-180	-	-	-	S	-	-	-	GNAT acetyltransferase
KGFKFCOI_04228	2.23e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KGFKFCOI_04230	6.12e-314	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
KGFKFCOI_04232	0.0	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_04234	0.0	-	-	-	-	-	-	-	-
KGFKFCOI_04235	1.29e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_04236	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
KGFKFCOI_04237	9.65e-157	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
KGFKFCOI_04238	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
KGFKFCOI_04239	1.85e-156	M1-740	-	-	I	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KGFKFCOI_04240	1.82e-226	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
KGFKFCOI_04241	9.85e-81	-	-	-	S	-	-	-	CHY zinc finger
KGFKFCOI_04242	4.21e-302	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KGFKFCOI_04243	1.01e-114	sdpI	-	-	S	-	-	-	integral membrane protein
KGFKFCOI_04244	1.47e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KGFKFCOI_04245	7.98e-137	-	-	-	S	ko:K09962	-	ko00000	protein conserved in bacteria
KGFKFCOI_04246	1.2e-190	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
KGFKFCOI_04247	2.86e-304	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KGFKFCOI_04248	1.32e-61	phhB	3.5.4.33, 4.2.1.96	-	H	ko:K01724,ko:K11991	ko00790,map00790	ko00000,ko00001,ko01000,ko03016,ko04147	pterin-4-alpha-carbinolamine dehydratase
KGFKFCOI_04249	7.69e-87	eaeH	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	LysM domain
KGFKFCOI_04250	2.58e-93	-	-	-	S	-	-	-	YtkA-like
KGFKFCOI_04251	0.0	-	-	-	T	-	-	-	Histidine kinase
KGFKFCOI_04252	1.75e-157	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_04253	2.07e-237	-	-	-	S	-	-	-	amine dehydrogenase activity
KGFKFCOI_04254	2.26e-249	-	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
KGFKFCOI_04256	6.91e-45	-	-	-	-	-	-	-	-
KGFKFCOI_04258	2.89e-152	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KGFKFCOI_04259	4.59e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_04261	1.25e-140	-	-	-	S	-	-	-	DUF218 domain
KGFKFCOI_04262	8.33e-193	degV	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04263	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGFKFCOI_04264	4.64e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGFKFCOI_04265	3.5e-292	yciC	-	-	S	-	-	-	GTPases (G3E family)
KGFKFCOI_04266	5.66e-168	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
KGFKFCOI_04267	3.33e-241	mhqA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
KGFKFCOI_04268	0.0	-	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182	ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the UbiD family
KGFKFCOI_04269	1.51e-147	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KGFKFCOI_04270	1.29e-169	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KGFKFCOI_04271	7.98e-309	atoE	-	-	I	ko:K02106	ko02020,map02020	ko00000,ko00001	Short chain fatty acid transporter
KGFKFCOI_04272	6.72e-242	malR	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_04273	2.79e-190	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
KGFKFCOI_04274	0.0	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
KGFKFCOI_04275	3.13e-310	malE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
KGFKFCOI_04276	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
KGFKFCOI_04278	1.61e-312	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
KGFKFCOI_04279	3.06e-285	codB	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
KGFKFCOI_04281	0.0	-	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
KGFKFCOI_04282	5.37e-292	lhgO	1.1.5.3	-	S	ko:K00111,ko:K15736	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
KGFKFCOI_04283	0.0	-	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
KGFKFCOI_04284	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
KGFKFCOI_04285	2.56e-162	-	-	-	K	-	-	-	COG2186 Transcriptional regulators
KGFKFCOI_04286	1.26e-155	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
KGFKFCOI_04287	0.0	-	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
KGFKFCOI_04288	2.94e-237	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
KGFKFCOI_04289	4.53e-206	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
KGFKFCOI_04290	1.03e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
KGFKFCOI_04291	8.5e-271	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
KGFKFCOI_04292	2.99e-98	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_04293	4.35e-238	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
KGFKFCOI_04294	2.39e-155	kdgR	-	-	K	-	-	-	FCD
KGFKFCOI_04295	1.67e-251	yjmC	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
KGFKFCOI_04296	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
KGFKFCOI_04297	1.53e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KGFKFCOI_04298	2.92e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
KGFKFCOI_04299	6.65e-236	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
KGFKFCOI_04300	4.83e-98	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
KGFKFCOI_04301	3.45e-150	-	-	-	S	-	-	-	CGNR zinc finger
KGFKFCOI_04303	2.42e-110	-	-	-	-	-	-	-	-
KGFKFCOI_04304	0.0	-	-	-	T	-	-	-	Carbon starvation protein
KGFKFCOI_04305	2.58e-173	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
KGFKFCOI_04306	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_04307	1.26e-136	-	-	-	K	-	-	-	Transcriptional regulator
KGFKFCOI_04308	0.0	ydfJ	-	-	S	ko:K07003	-	ko00000	MMPL family
KGFKFCOI_04309	3.26e-265	-	-	-	S	-	-	-	domain protein
KGFKFCOI_04310	5.07e-235	oppF3	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_04311	4.14e-231	oppD3	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KGFKFCOI_04312	5.32e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_04313	1.88e-223	appB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFKFCOI_04314	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KGFKFCOI_04315	5.96e-12	-	-	-	-	-	-	-	-
KGFKFCOI_04316	1.08e-176	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
KGFKFCOI_04317	2.67e-144	-	-	-	S	-	-	-	ABC-2 family transporter protein
KGFKFCOI_04318	7.45e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KGFKFCOI_04319	6.19e-94	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KGFKFCOI_04320	3.95e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
KGFKFCOI_04321	4.46e-131	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KGFKFCOI_04322	1.27e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KGFKFCOI_04323	3.41e-256	-	-	-	M	ko:K19504	-	ko00000	SIS domain
KGFKFCOI_04324	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	PTS system fructose IIA component
KGFKFCOI_04325	8.11e-159	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
KGFKFCOI_04326	1.03e-269	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
KGFKFCOI_04327	1.83e-101	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
KGFKFCOI_04328	4.88e-236	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KGFKFCOI_04329	2.17e-242	tdh	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
KGFKFCOI_04330	1.46e-142	-	-	-	K	-	-	-	FCD domain
KGFKFCOI_04331	1.87e-316	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
KGFKFCOI_04332	2.65e-214	-	-	-	-	-	-	-	-
KGFKFCOI_04333	2.4e-181	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KGFKFCOI_04334	9.49e-175	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	O-methyltransferase
KGFKFCOI_04335	1.12e-175	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
KGFKFCOI_04336	0.0	-	-	-	F	-	-	-	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KGFKFCOI_04337	2.27e-174	-	-	-	-	-	-	-	-
KGFKFCOI_04338	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
KGFKFCOI_04341	2.57e-140	-	-	-	-	-	-	-	-
KGFKFCOI_04343	1.43e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KGFKFCOI_04344	6.27e-271	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KGFKFCOI_04345	5.69e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KGFKFCOI_04346	2.27e-214	yycI	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04347	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04348	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KGFKFCOI_04349	7.17e-171	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFKFCOI_04355	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KGFKFCOI_04356	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KGFKFCOI_04357	1.71e-89	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KGFKFCOI_04358	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KGFKFCOI_04359	7.84e-191	yybS	-	-	S	-	-	-	membrane
KGFKFCOI_04360	4.32e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KGFKFCOI_04361	4.35e-92	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGFKFCOI_04362	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KGFKFCOI_04363	6.91e-247	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KGFKFCOI_04364	1.19e-37	yyzM	-	-	S	-	-	-	protein conserved in bacteria
KGFKFCOI_04365	4.33e-223	yyaD	-	-	S	-	-	-	Membrane
KGFKFCOI_04366	7.22e-149	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
KGFKFCOI_04367	8.36e-278	-	-	-	E	-	-	-	Aminotransferase class-V
KGFKFCOI_04368	7.4e-195	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KGFKFCOI_04369	2.04e-174	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
KGFKFCOI_04370	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KGFKFCOI_04371	2.49e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KGFKFCOI_04372	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KGFKFCOI_04373	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KGFKFCOI_04374	6.15e-146	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
KGFKFCOI_04375	7.48e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGFKFCOI_04376	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KGFKFCOI_04377	2.52e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family