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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IIKHECMK_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIKHECMK_00002	1.57e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIKHECMK_00003	9.5e-39	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
IIKHECMK_00004	1.06e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIKHECMK_00005	4.43e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIKHECMK_00006	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIKHECMK_00007	3.77e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IIKHECMK_00008	8.2e-81	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IIKHECMK_00009	1.94e-05	-	-	-	-	-	-	-	-
IIKHECMK_00010	3.78e-307	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
IIKHECMK_00011	1.87e-307	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIKHECMK_00012	2.22e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IIKHECMK_00013	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIKHECMK_00014	3.83e-173	-	-	-	L	-	-	-	Transposase
IIKHECMK_00015	3.83e-61	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_00016	1.45e-29	-	-	-	L	-	-	-	Transposase
IIKHECMK_00017	1.54e-73	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00018	1.09e-115	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00037	2.45e-182	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IIKHECMK_00038	1.52e-116	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IIKHECMK_00039	4.75e-168	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
IIKHECMK_00040	2.75e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIKHECMK_00041	2.17e-35	-	-	-	-	-	-	-	-
IIKHECMK_00042	1.06e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIKHECMK_00043	5.05e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IIKHECMK_00044	1.33e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIKHECMK_00045	1.93e-46	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIKHECMK_00046	1.5e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IIKHECMK_00047	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIKHECMK_00048	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIKHECMK_00049	5.98e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IIKHECMK_00050	6.85e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIKHECMK_00051	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IIKHECMK_00052	1.77e-65	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_00053	6.93e-68	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00054	7.27e-206	-	-	-	S	-	-	-	CHAP domain
IIKHECMK_00055	1.65e-305	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IIKHECMK_00056	2.66e-99	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIKHECMK_00057	1.03e-261	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIKHECMK_00058	1.69e-181	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
IIKHECMK_00059	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIKHECMK_00060	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIKHECMK_00061	1.36e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IIKHECMK_00062	5.42e-75	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IIKHECMK_00063	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIKHECMK_00064	6.4e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
IIKHECMK_00065	2.17e-81	-	-	-	KT	-	-	-	phosphorelay signal transduction system
IIKHECMK_00067	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIKHECMK_00069	3.08e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIKHECMK_00070	1.07e-36	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
IIKHECMK_00071	1.19e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IIKHECMK_00072	3.79e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIKHECMK_00073	1.27e-86	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IIKHECMK_00087	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIKHECMK_00088	1.46e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IIKHECMK_00089	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
IIKHECMK_00090	1.44e-72	badR	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IIKHECMK_00091	1.13e-125	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
IIKHECMK_00092	6.05e-113	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00093	1.44e-51	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00095	3.12e-100	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	carboxypeptidase activity
IIKHECMK_00096	1.46e-118	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IIKHECMK_00098	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IIKHECMK_00099	1.73e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIKHECMK_00100	3.55e-109	-	-	-	S	-	-	-	Putative small multi-drug export protein
IIKHECMK_00101	1.15e-98	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IIKHECMK_00102	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IIKHECMK_00103	1.96e-130	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIKHECMK_00104	3.56e-65	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIKHECMK_00105	6.81e-295	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIKHECMK_00106	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IIKHECMK_00107	3.84e-185	-	-	-	S	-	-	-	SseB protein N-terminal domain
IIKHECMK_00108	7.75e-145	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
IIKHECMK_00109	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IIKHECMK_00110	2.1e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIKHECMK_00113	1.23e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIKHECMK_00114	6.97e-121	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IIKHECMK_00115	1.5e-197	yitS	-	-	S	-	-	-	DegV family
IIKHECMK_00116	1.22e-42	-	-	-	K	-	-	-	helix-turn-helix
IIKHECMK_00117	4e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIKHECMK_00118	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIKHECMK_00119	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IIKHECMK_00120	3.37e-43	-	-	-	K	-	-	-	Peptidase S24-like
IIKHECMK_00122	6.28e-125	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
IIKHECMK_00123	0.0	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
IIKHECMK_00124	1.97e-295	spaC2	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C family protein
IIKHECMK_00125	2.6e-236	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIKHECMK_00126	5.31e-120	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
IIKHECMK_00127	3.75e-63	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIKHECMK_00128	9.43e-34	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIKHECMK_00129	8.09e-19	-	-	-	S	-	-	-	Helix-turn-helix domain
IIKHECMK_00131	1.43e-169	-	-	-	-	-	-	-	-
IIKHECMK_00132	2.1e-52	-	-	-	-	-	-	-	-
IIKHECMK_00133	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00134	4.98e-96	isp2	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
IIKHECMK_00135	7.63e-117	-	-	-	L	ko:K07498	-	ko00000	Transposase
IIKHECMK_00136	1.81e-55	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
IIKHECMK_00137	9.29e-138	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
IIKHECMK_00138	4.9e-72	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
IIKHECMK_00139	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
IIKHECMK_00140	4.59e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IIKHECMK_00141	9.09e-173	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
IIKHECMK_00142	5.21e-183	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IIKHECMK_00143	2.17e-133	acmA	3.2.1.17	-	NU	ko:K01185,ko:K02395	-	ko00000,ko01000,ko02035	amidase activity
IIKHECMK_00144	4.82e-254	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIKHECMK_00145	8.45e-107	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIKHECMK_00146	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IIKHECMK_00147	4.85e-258	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIKHECMK_00148	7.45e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIKHECMK_00149	2.58e-177	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
IIKHECMK_00150	2.97e-82	hmpT	-	-	S	-	-	-	membrane
IIKHECMK_00163	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IIKHECMK_00164	3.11e-219	-	-	-	L	-	-	-	Transposase
IIKHECMK_00165	2.36e-73	amd	-	-	E	-	-	-	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIKHECMK_00166	9.7e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IIKHECMK_00167	2.46e-113	-	-	-	-	-	-	-	-
IIKHECMK_00168	7.24e-102	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
IIKHECMK_00169	4.13e-192	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IIKHECMK_00170	6.47e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIKHECMK_00171	6.13e-119	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIKHECMK_00172	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIKHECMK_00173	5.04e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
IIKHECMK_00174	1.61e-75	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IIKHECMK_00175	3.13e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IIKHECMK_00176	7.42e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIKHECMK_00177	4.62e-40	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
IIKHECMK_00178	3.79e-176	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIKHECMK_00179	1.96e-228	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIKHECMK_00180	8.28e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
IIKHECMK_00181	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIKHECMK_00182	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIKHECMK_00183	3.09e-13	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IIKHECMK_00184	3.58e-33	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IIKHECMK_00185	2.53e-75	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IIKHECMK_00186	1.1e-67	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
IIKHECMK_00187	9.52e-303	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IIKHECMK_00188	2.96e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIKHECMK_00189	6.64e-146	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IIKHECMK_00190	6.09e-257	XK27_00055	-	-	P	-	-	-	Major Facilitator
IIKHECMK_00191	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIKHECMK_00192	8.47e-126	-	-	-	V	-	-	-	VanZ like family
IIKHECMK_00193	1.42e-09	-	-	-	D	-	-	-	nuclear chromosome segregation
IIKHECMK_00195	6.06e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_00196	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIKHECMK_00197	1.43e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIKHECMK_00198	6.09e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIKHECMK_00199	1.25e-248	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IIKHECMK_00200	1.82e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IIKHECMK_00201	1.7e-298	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IIKHECMK_00202	4.01e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIKHECMK_00203	2.78e-98	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IIKHECMK_00204	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IIKHECMK_00205	7.71e-24	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IIKHECMK_00206	7.77e-178	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IIKHECMK_00207	3.19e-36	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIKHECMK_00208	4.03e-14	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIKHECMK_00209	1.35e-64	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIKHECMK_00210	3.82e-77	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIKHECMK_00211	9.63e-38	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_00212	1.15e-43	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_00213	8.02e-89	-	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_00214	1.76e-59	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_00215	7.63e-220	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_00216	1.2e-15	-	-	-	-	-	-	-	-
IIKHECMK_00217	3.85e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIKHECMK_00218	2.41e-234	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIKHECMK_00219	1.06e-163	-	-	-	K	ko:K20374,ko:K21405	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IIKHECMK_00220	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
IIKHECMK_00221	1.03e-284	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IIKHECMK_00222	1.28e-94	adcR	-	-	K	-	-	-	transcriptional
IIKHECMK_00223	2.06e-174	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIKHECMK_00224	1.14e-161	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_00225	2.93e-208	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
IIKHECMK_00226	2.5e-86	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00227	8.33e-30	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00228	5.41e-202	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00229	5.86e-139	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IIKHECMK_00230	8.14e-201	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
IIKHECMK_00231	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IIKHECMK_00232	1.6e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IIKHECMK_00233	9.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
IIKHECMK_00234	1.76e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIKHECMK_00235	1.29e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IIKHECMK_00236	1.28e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IIKHECMK_00237	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIKHECMK_00238	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IIKHECMK_00239	4.1e-181	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_00240	4.47e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIKHECMK_00241	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIKHECMK_00242	1.05e-99	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_00243	6.93e-68	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00244	2.92e-46	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00247	1.35e-56	-	-	-	-	-	-	-	-
IIKHECMK_00248	1.15e-39	-	-	-	J	-	-	-	TM2 domain
IIKHECMK_00249	5.78e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IIKHECMK_00250	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIKHECMK_00251	1.27e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
IIKHECMK_00252	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IIKHECMK_00253	4.1e-111	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
IIKHECMK_00254	2.86e-74	cof	-	-	Q	-	-	-	phosphatase activity
IIKHECMK_00255	3.96e-49	cof	-	-	Q	-	-	-	phosphatase activity
IIKHECMK_00256	2.29e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
IIKHECMK_00257	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IIKHECMK_00258	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00259	1.93e-122	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
IIKHECMK_00260	1.2e-186	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IIKHECMK_00261	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIKHECMK_00262	6.15e-195	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIKHECMK_00263	1.13e-98	yhaI	-	-	L	-	-	-	Membrane
IIKHECMK_00264	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IIKHECMK_00265	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIKHECMK_00266	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIKHECMK_00267	8.82e-124	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IIKHECMK_00268	5.86e-68	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIKHECMK_00269	1.07e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IIKHECMK_00270	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IIKHECMK_00271	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00272	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
IIKHECMK_00273	3.69e-27	XK27_11680	-	-	-	-	-	-	-
IIKHECMK_00274	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IIKHECMK_00275	5.33e-76	XK27_09675	-	-	K	ko:K07105	-	ko00000	-acetyltransferase
IIKHECMK_00276	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIKHECMK_00277	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIKHECMK_00278	1.13e-108	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00279	5.31e-212	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIKHECMK_00280	9.51e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IIKHECMK_00281	2.78e-168	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIKHECMK_00282	8.25e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
IIKHECMK_00283	2.43e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IIKHECMK_00286	1.42e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIKHECMK_00287	3.67e-120	-	-	-	K	-	-	-	transcriptional regulator
IIKHECMK_00288	5.74e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IIKHECMK_00289	9.38e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IIKHECMK_00290	2.33e-236	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIKHECMK_00291	7.82e-128	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IIKHECMK_00292	1.49e-112	ykuL	-	-	S	-	-	-	CBS domain
IIKHECMK_00293	3.55e-176	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IIKHECMK_00294	1.66e-156	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIKHECMK_00295	7.56e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIKHECMK_00296	3.14e-179	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIKHECMK_00297	6.55e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IIKHECMK_00298	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
IIKHECMK_00299	2.41e-315	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
IIKHECMK_00300	1.34e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIKHECMK_00301	4.83e-118	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIKHECMK_00302	2.22e-146	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
IIKHECMK_00303	5.08e-207	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IIKHECMK_00304	3.36e-46	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
IIKHECMK_00305	7.97e-147	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIKHECMK_00306	5.61e-46	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
IIKHECMK_00307	4.06e-81	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
IIKHECMK_00308	9.82e-92	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIKHECMK_00309	6.22e-58	yhaI	-	-	L	-	-	-	Membrane
IIKHECMK_00310	9.51e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
IIKHECMK_00311	1.17e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
IIKHECMK_00312	7.25e-123	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
IIKHECMK_00313	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IIKHECMK_00314	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IIKHECMK_00315	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IIKHECMK_00316	2.74e-101	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
IIKHECMK_00317	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIKHECMK_00318	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IIKHECMK_00319	2.96e-205	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIKHECMK_00320	7.11e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
IIKHECMK_00321	1.18e-176	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
IIKHECMK_00322	4.48e-170	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIKHECMK_00323	9.07e-197	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
IIKHECMK_00324	1.26e-212	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IIKHECMK_00325	8.99e-114	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IIKHECMK_00326	1.48e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
IIKHECMK_00327	2.79e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
IIKHECMK_00328	2.17e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIKHECMK_00329	1.77e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_00330	9.46e-264	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IIKHECMK_00331	1.03e-202	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IIKHECMK_00332	5.41e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IIKHECMK_00333	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_00334	1.18e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IIKHECMK_00335	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIKHECMK_00336	2.41e-15	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ascorbate 6-phosphate lactonase
IIKHECMK_00337	1.98e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IIKHECMK_00338	3.5e-310	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
IIKHECMK_00339	1.5e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
IIKHECMK_00340	7.37e-120	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IIKHECMK_00341	2.69e-158	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIKHECMK_00342	0.0	covS	-	-	T	-	-	-	Histidine kinase
IIKHECMK_00343	1.46e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIKHECMK_00344	7.74e-278	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IIKHECMK_00345	5.34e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IIKHECMK_00346	1.72e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IIKHECMK_00347	0.0	-	-	-	P	-	-	-	ABC transporter transmembrane region
IIKHECMK_00349	1.79e-63	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_00350	2.92e-188	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_00351	5.89e-30	-	-	-	S	-	-	-	Protein of unknown function DUF262
IIKHECMK_00352	4.86e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIKHECMK_00353	7.55e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
IIKHECMK_00354	2.99e-217	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
IIKHECMK_00355	4.38e-164	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
IIKHECMK_00356	5.66e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00357	1.76e-180	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
IIKHECMK_00358	1.46e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IIKHECMK_00359	3.52e-316	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IIKHECMK_00360	1.54e-101	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IIKHECMK_00361	6.67e-120	-	-	-	M	-	-	-	Acetyltransferase GNAT Family
IIKHECMK_00362	5.27e-280	brpA	-	-	K	-	-	-	Transcriptional
IIKHECMK_00363	3.06e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IIKHECMK_00364	2.65e-270	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IIKHECMK_00365	6.68e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
IIKHECMK_00366	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
IIKHECMK_00367	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIKHECMK_00368	9.81e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIKHECMK_00369	1.44e-29	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IIKHECMK_00370	1.63e-50	-	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IIKHECMK_00371	9.48e-300	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
IIKHECMK_00372	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIKHECMK_00373	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IIKHECMK_00374	3.07e-114	pacL	-	-	P	-	-	-	cation transport ATPase
IIKHECMK_00375	1.76e-258	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IIKHECMK_00376	5.65e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IIKHECMK_00377	3.28e-06	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
IIKHECMK_00378	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIKHECMK_00379	2.64e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIKHECMK_00380	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IIKHECMK_00381	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
IIKHECMK_00382	3.94e-271	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IIKHECMK_00383	8.19e-190	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIKHECMK_00384	7.76e-183	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIKHECMK_00385	6.57e-176	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IIKHECMK_00386	1.32e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IIKHECMK_00387	2.41e-92	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
IIKHECMK_00388	1.52e-57	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
IIKHECMK_00389	1.3e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIKHECMK_00390	3.86e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IIKHECMK_00391	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IIKHECMK_00392	1.02e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IIKHECMK_00393	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIKHECMK_00394	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00402	9.95e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IIKHECMK_00403	9.03e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
IIKHECMK_00404	9.83e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IIKHECMK_00405	3.96e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IIKHECMK_00406	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIKHECMK_00407	9.23e-246	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IIKHECMK_00408	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IIKHECMK_00409	5.07e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IIKHECMK_00410	4.99e-180	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
IIKHECMK_00411	5.39e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
IIKHECMK_00412	1.88e-224	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIKHECMK_00413	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIKHECMK_00414	1.13e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
IIKHECMK_00415	3.32e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IIKHECMK_00416	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IIKHECMK_00417	2.6e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIKHECMK_00418	2.89e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIKHECMK_00419	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIKHECMK_00420	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IIKHECMK_00421	7.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIKHECMK_00422	1.88e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IIKHECMK_00423	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIKHECMK_00424	9.82e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase
IIKHECMK_00425	1.63e-313	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IIKHECMK_00426	3.04e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_00427	1.37e-165	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
IIKHECMK_00428	5.31e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IIKHECMK_00429	8.93e-68	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IIKHECMK_00430	5.31e-29	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
IIKHECMK_00431	2.69e-35	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IIKHECMK_00432	1.1e-129	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IIKHECMK_00433	1.53e-63	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IIKHECMK_00434	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIKHECMK_00435	2.19e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIKHECMK_00437	1.8e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IIKHECMK_00438	4.96e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIKHECMK_00439	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IIKHECMK_00440	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IIKHECMK_00441	1.12e-50	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
IIKHECMK_00442	1.13e-37	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
IIKHECMK_00443	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IIKHECMK_00444	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IIKHECMK_00445	1.11e-128	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIKHECMK_00446	2.91e-50	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIKHECMK_00447	3.89e-84	WQ51_03320	-	-	S	-	-	-	cog cog4835
IIKHECMK_00448	5.79e-43	XK27_08360	-	-	S	-	-	-	lipid binding
IIKHECMK_00449	2.03e-141	degV	-	-	T	-	-	-	EDD domain protein, DegV family
IIKHECMK_00450	6.34e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIKHECMK_00451	7.9e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIKHECMK_00452	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_00453	4.47e-27	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IIKHECMK_00454	1.68e-176	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
IIKHECMK_00455	2.03e-275	nadR	-	-	H	-	-	-	adenylyltransferase
IIKHECMK_00456	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IIKHECMK_00457	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIKHECMK_00459	4.4e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IIKHECMK_00460	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_00461	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_00462	1.86e-157	sptS	-	-	T	-	-	-	Histidine kinase
IIKHECMK_00463	1.38e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IIKHECMK_00464	6.76e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIKHECMK_00465	9.65e-206	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
IIKHECMK_00466	3.3e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IIKHECMK_00467	4.78e-189	usp	3.5.1.104, 3.5.1.28	CBM50	S	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133	ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	pathogenesis
IIKHECMK_00469	1.99e-193	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_00470	7.98e-17	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_00471	1.12e-90	sip	-	-	M	-	-	-	LysM domain protein
IIKHECMK_00472	9.19e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IIKHECMK_00476	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIKHECMK_00477	9.23e-214	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
IIKHECMK_00478	3.31e-238	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IIKHECMK_00479	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IIKHECMK_00480	2.39e-164	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
IIKHECMK_00481	3.25e-237	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
IIKHECMK_00482	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIKHECMK_00483	1.22e-29	-	-	-	M	-	-	-	GBS Bsp-like repeat
IIKHECMK_00484	4.2e-131	-	-	-	M	-	-	-	GBS Bsp-like repeat
IIKHECMK_00485	6.15e-57	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
IIKHECMK_00486	2.35e-184	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
IIKHECMK_00487	2.32e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIKHECMK_00488	8.57e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
IIKHECMK_00489	8.21e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIKHECMK_00490	4.21e-285	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIKHECMK_00491	7.33e-164	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IIKHECMK_00492	6.48e-267	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IIKHECMK_00493	5e-182	icaB	-	-	G	-	-	-	deacetylase
IIKHECMK_00494	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IIKHECMK_00495	1.29e-198	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIKHECMK_00496	1.89e-194	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
IIKHECMK_00498	3.61e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IIKHECMK_00499	1.55e-131	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IIKHECMK_00500	7.34e-63	-	2.3.1.128, 5.2.1.8	-	J	ko:K03768,ko:K03790	-	ko00000,ko01000,ko03009,ko03110	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIKHECMK_00501	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIKHECMK_00502	1.19e-22	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIKHECMK_00503	2.46e-157	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IIKHECMK_00504	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase F(0) sector subunit b
IIKHECMK_00505	1.05e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIKHECMK_00506	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIKHECMK_00507	9.48e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIKHECMK_00508	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIKHECMK_00509	6.23e-97	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IIKHECMK_00510	1.43e-292	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IIKHECMK_00511	7.86e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIKHECMK_00512	6.58e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIKHECMK_00513	5.91e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIKHECMK_00514	2.73e-207	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
IIKHECMK_00515	4.95e-178	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IIKHECMK_00516	2.84e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IIKHECMK_00517	7.25e-206	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIKHECMK_00518	1.26e-297	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
IIKHECMK_00519	3.27e-71	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IIKHECMK_00520	2.28e-140	mur1	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	mannosyl-glycoprotein
IIKHECMK_00521	7.55e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IIKHECMK_00522	2.01e-42	phoU_1	-	-	P	ko:K03324	-	ko00000,ko02000	sodium-dependent phosphate transmembrane transporter activity
IIKHECMK_00523	1.23e-106	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IIKHECMK_00524	4.81e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIKHECMK_00525	4.34e-73	-	-	-	-	-	-	-	-
IIKHECMK_00526	3.92e-34	-	-	-	-	-	-	-	-
IIKHECMK_00527	3.77e-81	-	-	-	-	-	-	-	-
IIKHECMK_00528	2.48e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IIKHECMK_00529	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IIKHECMK_00530	1.42e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
IIKHECMK_00531	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
IIKHECMK_00533	3.11e-35	-	2.7.1.208, 2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IIKHECMK_00534	6.05e-93	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00535	2.57e-121	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_00536	2.72e-102	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS glucose transporter subunit IIA
IIKHECMK_00537	3.54e-179	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIKHECMK_00542	3.2e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
IIKHECMK_00543	1.4e-100	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIKHECMK_00544	1.95e-197	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IIKHECMK_00545	6.68e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIKHECMK_00546	2.87e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
IIKHECMK_00547	8.28e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IIKHECMK_00548	1.12e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
IIKHECMK_00549	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
IIKHECMK_00550	4.63e-175	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
IIKHECMK_00551	1.86e-34	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIKHECMK_00552	4.46e-48	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIKHECMK_00553	5.34e-54	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
IIKHECMK_00554	8.95e-44	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
IIKHECMK_00555	6.91e-34	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
IIKHECMK_00556	4.71e-37	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	efflux transmembrane transporter activity
IIKHECMK_00557	3.14e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIKHECMK_00558	2.46e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIKHECMK_00560	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_00561	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_00562	1.09e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIKHECMK_00563	1.03e-163	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIKHECMK_00564	2.59e-294	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
IIKHECMK_00565	3.51e-170	rr02	-	-	KT	-	-	-	response regulator
IIKHECMK_00566	1.26e-101	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIKHECMK_00567	6.61e-162	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIKHECMK_00568	1.17e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IIKHECMK_00569	1.79e-157	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IIKHECMK_00570	3.93e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IIKHECMK_00571	3.94e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
IIKHECMK_00573	3.69e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
IIKHECMK_00574	8.88e-147	-	-	-	S	-	-	-	VIT family
IIKHECMK_00575	3.68e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIKHECMK_00576	3.04e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIKHECMK_00577	1.29e-24	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	alanine dehydrogenase activity
IIKHECMK_00578	3.82e-57	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IIKHECMK_00580	0.0	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIKHECMK_00581	3.96e-137	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
IIKHECMK_00582	2.19e-193	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
IIKHECMK_00583	3.24e-222	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IIKHECMK_00584	8.32e-229	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IIKHECMK_00585	3.21e-244	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIKHECMK_00586	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIKHECMK_00587	1.23e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
IIKHECMK_00588	1.47e-41	-	-	-	-	-	-	-	-
IIKHECMK_00589	7.33e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIKHECMK_00591	9.15e-10	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
IIKHECMK_00592	1.15e-59	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
IIKHECMK_00593	4.93e-243	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIKHECMK_00594	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IIKHECMK_00595	5.47e-29	-	-	-	-	-	-	-	-
IIKHECMK_00596	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIKHECMK_00597	2.88e-220	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIKHECMK_00598	2.02e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
IIKHECMK_00599	6.8e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
IIKHECMK_00600	1.05e-153	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IIKHECMK_00601	6.15e-298	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IIKHECMK_00602	3.13e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
IIKHECMK_00603	3.63e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIKHECMK_00604	7.02e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIKHECMK_00605	2.97e-30	-	-	-	-	-	-	-	-
IIKHECMK_00606	8.89e-288	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIKHECMK_00607	6.75e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IIKHECMK_00608	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IIKHECMK_00609	8.31e-226	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
IIKHECMK_00610	5.22e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
IIKHECMK_00611	1.1e-20	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
IIKHECMK_00612	1.49e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIKHECMK_00613	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIKHECMK_00614	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIKHECMK_00615	4.29e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIKHECMK_00616	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IIKHECMK_00619	1.44e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
IIKHECMK_00622	9.86e-38	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IIKHECMK_00623	5.3e-41	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IIKHECMK_00624	1.37e-87	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
IIKHECMK_00625	1.33e-295	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
IIKHECMK_00626	8.6e-11	-	-	-	S	-	-	-	oxidoreductase
IIKHECMK_00627	1.61e-36	-	2.7.7.15	-	S	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	inositol 2-dehydrogenase activity
IIKHECMK_00628	2.66e-68	ydgJ	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	inositol 2-dehydrogenase activity
IIKHECMK_00629	5.47e-66	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IIKHECMK_00630	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IIKHECMK_00631	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IIKHECMK_00632	5.71e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIKHECMK_00633	1.15e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IIKHECMK_00634	3.24e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIKHECMK_00635	4.45e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_00636	8.63e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
IIKHECMK_00637	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
IIKHECMK_00638	6.95e-12	-	-	-	-	-	-	-	-
IIKHECMK_00639	2.87e-47	yugF	-	-	I	-	-	-	carboxylic ester hydrolase activity
IIKHECMK_00640	5.04e-29	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IIKHECMK_00641	1.71e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIKHECMK_00642	5.03e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIKHECMK_00643	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
IIKHECMK_00644	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIKHECMK_00645	3.61e-84	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IIKHECMK_00646	9.96e-69	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IIKHECMK_00647	2.18e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIKHECMK_00648	1.16e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IIKHECMK_00649	3.2e-210	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIKHECMK_00650	2.33e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIKHECMK_00651	3.51e-133	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIKHECMK_00652	7.22e-282	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
IIKHECMK_00653	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IIKHECMK_00654	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIKHECMK_00655	5.69e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIKHECMK_00656	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIKHECMK_00657	1.08e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
IIKHECMK_00658	9.95e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
IIKHECMK_00659	1.34e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
IIKHECMK_00660	1.2e-33	XK27_07735	-	-	S	-	-	-	YjbR
IIKHECMK_00661	9.83e-187	XK27_07735	-	-	S	-	-	-	YjbR
IIKHECMK_00662	1.71e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IIKHECMK_00663	1.03e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IIKHECMK_00664	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIKHECMK_00665	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IIKHECMK_00666	2.93e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IIKHECMK_00667	3.99e-158	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIKHECMK_00668	1.96e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIKHECMK_00669	2.5e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIKHECMK_00670	1.29e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIKHECMK_00671	1.11e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IIKHECMK_00672	1.48e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
IIKHECMK_00673	2.67e-222	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IIKHECMK_00674	1.02e-298	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIKHECMK_00675	1.6e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIKHECMK_00676	3.43e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IIKHECMK_00677	2.79e-85	msrR	-	-	K	-	-	-	Transcriptional regulator
IIKHECMK_00678	3.63e-224	msrR	-	-	K	-	-	-	Transcriptional regulator
IIKHECMK_00679	2.04e-204	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
IIKHECMK_00680	4.67e-258	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
IIKHECMK_00681	7.4e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
IIKHECMK_00682	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIKHECMK_00683	4.4e-110	-	-	-	-	-	-	-	-
IIKHECMK_00684	2.13e-44	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IIKHECMK_00685	4.96e-59	dam	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
IIKHECMK_00687	4.22e-122	-	-	-	-	-	-	-	-
IIKHECMK_00688	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIKHECMK_00689	6.55e-221	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIKHECMK_00690	3.44e-70	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIKHECMK_00691	1.96e-232	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
IIKHECMK_00692	5.43e-188	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
IIKHECMK_00693	9.75e-201	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
IIKHECMK_00695	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
IIKHECMK_00696	3.63e-113	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IIKHECMK_00697	5.93e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
IIKHECMK_00698	1.42e-218	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIKHECMK_00699	8.73e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIKHECMK_00700	1.07e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIKHECMK_00701	6.79e-90	ytxH	-	-	S	-	-	-	General stress protein
IIKHECMK_00703	1.5e-229	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IIKHECMK_00704	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IIKHECMK_00705	3.24e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
IIKHECMK_00707	4.22e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
IIKHECMK_00708	6.38e-298	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IIKHECMK_00710	7.77e-88	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IIKHECMK_00711	5.48e-123	-	-	-	L	-	-	-	helicase
IIKHECMK_00712	1.74e-52	-	-	-	-	-	-	-	-
IIKHECMK_00713	9.89e-51	-	-	-	-	-	-	-	-
IIKHECMK_00718	2.9e-26	-	-	-	K	-	-	-	Helix-turn-helix domain
IIKHECMK_00719	2.28e-30	-	-	-	-	-	-	-	-
IIKHECMK_00720	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00721	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IIKHECMK_00722	4.12e-28	-	-	-	M	-	-	-	LysM domain
IIKHECMK_00723	7.16e-70	-	-	-	M	-	-	-	LysM domain
IIKHECMK_00724	1.16e-78	-	-	-	M	-	-	-	LysM domain
IIKHECMK_00725	5.38e-30	-	-	-	-	-	-	-	-
IIKHECMK_00726	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
IIKHECMK_00727	3.06e-151	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
IIKHECMK_00728	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIKHECMK_00729	6.96e-197	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
IIKHECMK_00730	1.14e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
IIKHECMK_00731	6.94e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIKHECMK_00732	6.19e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IIKHECMK_00733	4.66e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IIKHECMK_00734	1.57e-170	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIKHECMK_00735	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IIKHECMK_00736	1.56e-306	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
IIKHECMK_00738	8.87e-287	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
IIKHECMK_00739	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
IIKHECMK_00740	4.14e-177	-	-	-	S	-	-	-	Protein conserved in bacteria
IIKHECMK_00741	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IIKHECMK_00742	2.51e-15	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
IIKHECMK_00743	8.28e-33	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
IIKHECMK_00744	3.33e-241	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IIKHECMK_00745	7.6e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IIKHECMK_00746	1.9e-186	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IIKHECMK_00747	1.74e-96	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
IIKHECMK_00748	2.18e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
IIKHECMK_00749	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IIKHECMK_00750	2.71e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IIKHECMK_00751	6.73e-145	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IIKHECMK_00752	7.26e-290	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
IIKHECMK_00753	3.17e-150	pppA	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
IIKHECMK_00754	2.24e-118	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IIKHECMK_00755	5.82e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IIKHECMK_00756	7.8e-38	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
IIKHECMK_00757	8.34e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IIKHECMK_00758	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IIKHECMK_00759	2.68e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
IIKHECMK_00760	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIKHECMK_00761	5.46e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIKHECMK_00762	2.43e-245	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIKHECMK_00763	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIKHECMK_00764	2.64e-303	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIKHECMK_00765	1.39e-159	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIKHECMK_00766	5.13e-125	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIKHECMK_00767	4.42e-47	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
IIKHECMK_00768	3.39e-184	ylmH	-	-	T	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	S4 RNA-binding domain
IIKHECMK_00769	5.11e-187	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division protein DivIVA
IIKHECMK_00770	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIKHECMK_00771	8.24e-25	-	-	-	-	-	-	-	-
IIKHECMK_00772	1.93e-12	-	-	-	-	-	-	-	-
IIKHECMK_00773	2.47e-291	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
IIKHECMK_00774	1.39e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
IIKHECMK_00775	6.83e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIKHECMK_00776	4.29e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
IIKHECMK_00777	6.55e-196	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
IIKHECMK_00778	1.92e-24	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IIKHECMK_00779	6.77e-202	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IIKHECMK_00780	1.16e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IIKHECMK_00781	5.57e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIKHECMK_00782	2.15e-197	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIKHECMK_00783	5.72e-139	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIKHECMK_00784	1.24e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIKHECMK_00785	1.82e-229	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
IIKHECMK_00786	3.79e-138	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
IIKHECMK_00787	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_00788	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_00789	3.08e-14	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IIKHECMK_00790	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIKHECMK_00791	2.52e-302	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
IIKHECMK_00792	4.98e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIKHECMK_00793	1.09e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIKHECMK_00794	2.06e-46	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00795	3.42e-41	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_00796	3.25e-70	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00797	1.12e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_00798	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
IIKHECMK_00799	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
IIKHECMK_00803	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
IIKHECMK_00804	1.77e-180	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
IIKHECMK_00805	1.9e-30	-	-	-	-	-	-	-	-
IIKHECMK_00810	1.71e-24	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IIKHECMK_00811	0.000205	-	-	-	K	-	-	-	Helix-turn-helix domain protein
IIKHECMK_00812	9.47e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIKHECMK_00814	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIKHECMK_00815	2.65e-212	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
IIKHECMK_00816	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IIKHECMK_00817	3.72e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IIKHECMK_00818	5.7e-124	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIKHECMK_00819	6.6e-158	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
IIKHECMK_00820	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IIKHECMK_00821	7.2e-109	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIKHECMK_00822	1.1e-50	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_00823	6.62e-53	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_00824	9.69e-165	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_00825	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
IIKHECMK_00826	3.22e-156	-	-	-	L	-	-	-	Transposase
IIKHECMK_00827	1.98e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
IIKHECMK_00828	1.22e-222	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IIKHECMK_00829	1.51e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
IIKHECMK_00830	6.15e-36	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
IIKHECMK_00831	5.3e-33	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
IIKHECMK_00832	6.61e-78	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IIKHECMK_00833	6.79e-85	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
IIKHECMK_00834	9.02e-28	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIKHECMK_00835	1.32e-83	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIKHECMK_00836	4.51e-75	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIKHECMK_00837	6.06e-246	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IIKHECMK_00838	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IIKHECMK_00839	3.21e-245	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIKHECMK_00840	5.16e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIKHECMK_00841	4.54e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IIKHECMK_00842	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IIKHECMK_00843	3.8e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IIKHECMK_00844	1.57e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IIKHECMK_00845	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIKHECMK_00848	1.84e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
IIKHECMK_00849	1.58e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IIKHECMK_00850	3.49e-107	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IIKHECMK_00851	7.78e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IIKHECMK_00852	4.7e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IIKHECMK_00853	4.9e-24	-	-	-	D	-	-	-	nuclear chromosome segregation
IIKHECMK_00854	3.26e-177	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
IIKHECMK_00855	5.97e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IIKHECMK_00856	2.6e-233	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IIKHECMK_00857	1.2e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IIKHECMK_00858	5.22e-117	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IIKHECMK_00859	4.41e-55	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
IIKHECMK_00860	4.24e-44	-	-	-	K	-	-	-	Cold shock protein domain
IIKHECMK_00861	3.71e-57	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-Shock Protein
IIKHECMK_00862	1.12e-286	-	-	-	L	-	-	-	Transposase, Mutator family
IIKHECMK_00863	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	P-type ATPase
IIKHECMK_00864	1.55e-112	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_00865	1.69e-112	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_00866	2.03e-250	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IIKHECMK_00867	1.8e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IIKHECMK_00868	2.93e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IIKHECMK_00869	7.37e-80	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
IIKHECMK_00870	8.38e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_00871	7.16e-77	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K07317	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
IIKHECMK_00872	2.42e-81	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IIKHECMK_00873	2.44e-43	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
IIKHECMK_00874	6.91e-203	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IIKHECMK_00875	5.25e-08	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
IIKHECMK_00876	4.83e-97	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
IIKHECMK_00877	4.37e-139	XK27_10720	-	-	D	-	-	-	peptidase activity
IIKHECMK_00878	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IIKHECMK_00881	3.33e-139	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_00882	2.29e-62	-	-	-	-	-	-	-	-
IIKHECMK_00883	6.17e-24	-	-	-	-	ko:K07485	-	ko00000	-
IIKHECMK_00884	1.3e-218	yeiH	-	-	S	-	-	-	Membrane
IIKHECMK_00885	4.02e-147	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
IIKHECMK_00886	3.89e-125	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_00887	2.18e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator
IIKHECMK_00888	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIKHECMK_00889	7.71e-77	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
IIKHECMK_00890	2.37e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_00891	5.28e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_00892	9.52e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIKHECMK_00893	1.97e-191	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIKHECMK_00894	2.18e-10	-	-	-	-	-	-	-	-
IIKHECMK_00895	5.44e-34	-	-	-	-	-	-	-	-
IIKHECMK_00896	1.96e-82	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIKHECMK_00897	2.22e-22	adhP	1.1.1.1	-	P	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIKHECMK_00898	3.63e-105	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
IIKHECMK_00899	7.95e-30	-	-	-	-	-	-	-	-
IIKHECMK_00900	0.0	sthIR	3.1.21.5	-	S	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction
IIKHECMK_00901	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
IIKHECMK_00902	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IIKHECMK_00903	2.59e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IIKHECMK_00904	9e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIKHECMK_00905	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIKHECMK_00906	5.63e-113	niaX	-	-	-	ko:K16788	-	ko00000,ko02000	-
IIKHECMK_00907	7.82e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IIKHECMK_00908	7.77e-167	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
IIKHECMK_00909	1.46e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIKHECMK_00910	1.72e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIKHECMK_00911	5.35e-217	-	-	-	GK	-	-	-	ROK family
IIKHECMK_00912	2e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IIKHECMK_00913	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIKHECMK_00914	1.03e-198	-	-	-	S	-	-	-	TraX protein
IIKHECMK_00915	2.93e-157	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIKHECMK_00916	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IIKHECMK_00917	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIKHECMK_00918	1.03e-197	XK27_05470	-	-	E	-	-	-	Methionine synthase
IIKHECMK_00919	1.01e-99	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IIKHECMK_00920	1.81e-61	pspE	-	-	P	ko:K03972	-	ko00000	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIKHECMK_00921	5.99e-118	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IIKHECMK_00922	3.14e-71	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
IIKHECMK_00923	1.01e-24	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
IIKHECMK_00924	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIKHECMK_00928	3.63e-71	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
IIKHECMK_00929	4.16e-199	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
IIKHECMK_00932	5.16e-272	nirJ	-	-	C	ko:K06139,ko:K22227	-	ko00000	radical SAM domain protein
IIKHECMK_00933	3.15e-175	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IIKHECMK_00934	9.01e-75	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
IIKHECMK_00935	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IIKHECMK_00936	1.34e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
IIKHECMK_00938	9.11e-178	-	-	-	L	-	-	-	Transposase
IIKHECMK_00939	7.98e-17	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_00940	2.23e-140	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_00941	7.85e-143	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIKHECMK_00942	9.28e-15	-	-	-	-	-	-	-	-
IIKHECMK_00943	8.71e-128	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
IIKHECMK_00944	9.1e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IIKHECMK_00945	4.65e-27	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IIKHECMK_00946	2.11e-69	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IIKHECMK_00947	2.72e-177	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IIKHECMK_00948	1.66e-30	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
IIKHECMK_00949	1.7e-207	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
IIKHECMK_00950	2.92e-11	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
IIKHECMK_00951	3.95e-24	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIKHECMK_00952	2.95e-104	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIKHECMK_00955	6.92e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
IIKHECMK_00956	2.4e-153	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
IIKHECMK_00957	2.48e-09	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IIKHECMK_00958	3.53e-24	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
IIKHECMK_00959	1.7e-95	dinF	-	-	V	-	-	-	Mate efflux family protein
IIKHECMK_00961	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IIKHECMK_00962	0.000908	-	-	-	S	-	-	-	TraX protein
IIKHECMK_00963	1.69e-116	-	-	-	S	-	-	-	TraX protein
IIKHECMK_00964	1.74e-124	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
IIKHECMK_00965	5.05e-191	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IIKHECMK_00966	7.37e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIKHECMK_00967	7.21e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
IIKHECMK_00968	6.04e-67	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
IIKHECMK_00969	2.69e-149	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
IIKHECMK_00970	2.1e-215	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
IIKHECMK_00971	3.18e-262	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm5 family
IIKHECMK_00972	7.98e-18	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IIKHECMK_00973	2.12e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IIKHECMK_00974	6.87e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIKHECMK_00975	6.16e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIKHECMK_00976	3.66e-11	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	amidase activity
IIKHECMK_00977	9.11e-77	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IIKHECMK_00978	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	transporter
IIKHECMK_00979	3.63e-49	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00980	9.48e-165	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_00981	1.62e-137	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
IIKHECMK_00982	5.13e-95	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_00983	4.82e-78	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_00984	1.15e-89	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_00985	7.45e-31	yecS	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid transport
IIKHECMK_00986	1.07e-09	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIKHECMK_00987	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIKHECMK_00988	3.06e-50	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
IIKHECMK_00989	4.28e-133	yfiF3	-	-	K	-	-	-	sequence-specific DNA binding
IIKHECMK_00990	1.76e-28	bglC	-	-	K	-	-	-	Transcriptional regulator
IIKHECMK_00991	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIKHECMK_00992	2.03e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
IIKHECMK_00993	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IIKHECMK_00994	2.08e-307	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
IIKHECMK_00995	6.24e-78	-	-	-	Q	-	-	-	phosphatase activity
IIKHECMK_00996	5.48e-79	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IIKHECMK_00997	1.48e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIKHECMK_00998	3.31e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
IIKHECMK_00999	2.2e-278	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
IIKHECMK_01000	4.02e-193	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIKHECMK_01001	4.8e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IIKHECMK_01002	8.79e-94	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIKHECMK_01003	1.7e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IIKHECMK_01004	5.9e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
IIKHECMK_01005	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IIKHECMK_01006	3.94e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
IIKHECMK_01007	4.63e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IIKHECMK_01008	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
IIKHECMK_01009	5.27e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIKHECMK_01010	1.24e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIKHECMK_01011	1.1e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IIKHECMK_01012	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IIKHECMK_01013	1.32e-249	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IIKHECMK_01015	2.63e-240	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IIKHECMK_01018	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IIKHECMK_01019	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
IIKHECMK_01020	2.89e-228	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIKHECMK_01021	6.6e-25	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IIKHECMK_01022	1.94e-18	malX	-	-	G	ko:K02027,ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	maltose binding
IIKHECMK_01023	3.01e-36	malX	-	-	G	ko:K02027,ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	maltose binding
IIKHECMK_01024	3.19e-69	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01025	1.17e-55	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01026	4.79e-34	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
IIKHECMK_01027	3.17e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIKHECMK_01028	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IIKHECMK_01029	2.59e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
IIKHECMK_01030	2.5e-199	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IIKHECMK_01031	1.38e-231	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
IIKHECMK_01032	1.75e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01033	6.34e-214	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIKHECMK_01034	7.09e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIKHECMK_01035	1.97e-43	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
IIKHECMK_01036	4.31e-270	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
IIKHECMK_01037	3.61e-67	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_01038	2.06e-190	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_01039	1e-35	-	-	-	-	-	-	-	-
IIKHECMK_01040	3.83e-35	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
IIKHECMK_01041	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_01043	2.04e-13	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIKHECMK_01044	8.28e-135	-	-	-	L	-	-	-	nUDIX hydrolase
IIKHECMK_01045	2.11e-221	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIKHECMK_01046	5.71e-201	-	-	-	K	ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
IIKHECMK_01047	1.16e-304	-	-	-	L	-	-	-	Transposase
IIKHECMK_01048	1.09e-91	-	3.2.1.17	-	M	ko:K01185,ko:K07273	-	ko00000,ko01000	lysozyme activity
IIKHECMK_01049	2.33e-29	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
IIKHECMK_01050	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
IIKHECMK_01051	2.12e-275	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIKHECMK_01052	3.38e-232	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIKHECMK_01053	1.07e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
IIKHECMK_01054	2.9e-53	-	-	-	P	-	-	-	membrane protein (DUF2207)
IIKHECMK_01055	9.16e-78	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IIKHECMK_01056	2.07e-300	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIKHECMK_01057	3.23e-162	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIKHECMK_01058	2.7e-277	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIKHECMK_01059	1.57e-33	dacA1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IIKHECMK_01060	3.4e-228	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
IIKHECMK_01061	5.5e-203	-	-	-	S	-	-	-	Phospholipase, patatin family
IIKHECMK_01062	1.43e-111	-	-	-	E	-	-	-	GDSL-like protein
IIKHECMK_01063	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
IIKHECMK_01064	8.7e-53	-	-	-	S	-	-	-	granule-associated protein
IIKHECMK_01065	4.17e-50	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IIKHECMK_01066	6.88e-58	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
IIKHECMK_01067	2.93e-130	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IIKHECMK_01068	6.76e-39	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
IIKHECMK_01069	2.04e-255	XK27_12525	-	-	S	-	-	-	hmm pf01594
IIKHECMK_01070	5.25e-114	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IIKHECMK_01071	8.95e-91	supH	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
IIKHECMK_01072	3.58e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_01073	8.61e-67	-	-	-	M	-	-	-	Glycosyl transferases group 1
IIKHECMK_01074	8.26e-87	-	-	-	L	ko:K07498	-	ko00000	DDE domain
IIKHECMK_01075	1.32e-11	-	-	-	L	ko:K07498	-	ko00000	DDE domain
IIKHECMK_01076	6.15e-118	-	-	-	V	-	-	-	VanZ like family
IIKHECMK_01077	4.28e-128	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
IIKHECMK_01078	8.18e-64	-	-	-	GM	-	-	-	Polysaccharide pyruvyl transferase
IIKHECMK_01079	6.09e-19	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IIKHECMK_01080	5.95e-08	-	-	-	S	-	-	-	EpsG family
IIKHECMK_01081	2.44e-72	-	-	-	S	-	-	-	Glycosyltransferase like family 2
IIKHECMK_01082	1.18e-48	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
IIKHECMK_01083	2.32e-67	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
IIKHECMK_01084	1.09e-103	-	-	-	M	-	-	-	Glycosyl transferase 4-like
IIKHECMK_01086	3.82e-74	-	-	-	M	-	-	-	Bacterial sugar transferase
IIKHECMK_01087	1.14e-150	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
IIKHECMK_01088	8.78e-144	capA	-	-	M	-	-	-	biosynthesis protein
IIKHECMK_01089	1.1e-173	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
IIKHECMK_01090	1.18e-303	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IIKHECMK_01091	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
IIKHECMK_01092	9.24e-153	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
IIKHECMK_01093	2.76e-84	clcA_2	-	-	P	ko:K03281	-	ko00000	chloride channel
IIKHECMK_01094	5.05e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IIKHECMK_01095	5.55e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
IIKHECMK_01096	4.48e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIKHECMK_01097	2.91e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIKHECMK_01098	4.42e-45	-	-	-	V	-	-	-	Glucan-binding protein C
IIKHECMK_01099	2.28e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
IIKHECMK_01100	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
IIKHECMK_01101	2.78e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IIKHECMK_01102	9.78e-112	XK27_03610	-	-	K	-	-	-	Gnat family
IIKHECMK_01103	1.39e-33	-	-	-	L	ko:K07491	-	ko00000	Transposase
IIKHECMK_01104	1.61e-55	-	-	-	L	ko:K07491	-	ko00000	Transposase
IIKHECMK_01105	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIKHECMK_01106	5.79e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IIKHECMK_01107	9.02e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIKHECMK_01108	1.44e-156	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IIKHECMK_01109	1.64e-42	XK27_09115	-	-	M	-	-	-	LysM domain
IIKHECMK_01110	1.12e-119	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
IIKHECMK_01111	1.76e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IIKHECMK_01112	1.13e-126	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIKHECMK_01113	1.34e-285	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
IIKHECMK_01114	2.58e-233	XK27_05220	-	-	S	-	-	-	permease
IIKHECMK_01115	3.52e-120	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIKHECMK_01116	1.99e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IIKHECMK_01117	1.04e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IIKHECMK_01118	5.35e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIKHECMK_01119	2.52e-262	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IIKHECMK_01120	1.01e-229	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IIKHECMK_01121	1.97e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
IIKHECMK_01122	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
IIKHECMK_01123	1.19e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IIKHECMK_01124	3.47e-69	XK27_00115	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
IIKHECMK_01125	5.66e-189	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
IIKHECMK_01126	1.05e-293	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
IIKHECMK_01127	1.77e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
IIKHECMK_01128	1.86e-316	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_01129	1.44e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIKHECMK_01130	3.14e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01131	5.66e-193	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIKHECMK_01132	2.9e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01133	6.09e-144	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IIKHECMK_01134	1.77e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IIKHECMK_01135	4.09e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
IIKHECMK_01136	5.05e-297	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIKHECMK_01138	1.05e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIKHECMK_01139	1.16e-17	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
IIKHECMK_01140	6.71e-266	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIKHECMK_01141	1.95e-222	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIKHECMK_01142	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIKHECMK_01143	2.25e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IIKHECMK_01144	1.82e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIKHECMK_01145	2.71e-27	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
IIKHECMK_01148	5.73e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIKHECMK_01149	7.16e-278	-	-	-	P	-	-	-	chloride
IIKHECMK_01150	1.27e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
IIKHECMK_01151	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
IIKHECMK_01152	4.07e-97	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IIKHECMK_01154	2.2e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
IIKHECMK_01155	1.84e-194	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
IIKHECMK_01156	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIKHECMK_01157	2.68e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01158	9.64e-191	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IIKHECMK_01159	4.13e-230	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IIKHECMK_01160	5.6e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4649)
IIKHECMK_01162	1.72e-50	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IIKHECMK_01163	1.12e-33	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IIKHECMK_01165	6.86e-11	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IIKHECMK_01167	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IIKHECMK_01168	1.04e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIKHECMK_01169	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IIKHECMK_01170	1.99e-194	XK27_00020	-	-	J	-	-	-	Belongs to the SUA5 family
IIKHECMK_01171	2.76e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIKHECMK_01172	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIKHECMK_01173	1.11e-55	ysdA	-	-	L	-	-	-	Membrane
IIKHECMK_01174	7.51e-242	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IIKHECMK_01175	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IIKHECMK_01176	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIKHECMK_01177	8.68e-163	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_01178	2.31e-230	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
IIKHECMK_01180	1.54e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIKHECMK_01181	7.29e-125	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
IIKHECMK_01182	1.09e-187	ypmR	-	-	E	-	-	-	lipolytic protein G-D-S-L family
IIKHECMK_01183	3.39e-190	WQ51_01275	-	-	S	-	-	-	DegV family
IIKHECMK_01184	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IIKHECMK_01185	1.26e-96	argR	-	-	K	ko:K03402	-	ko00000,ko03000	arginine binding
IIKHECMK_01186	2.83e-203	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IIKHECMK_01187	5.71e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IIKHECMK_01188	1.72e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
IIKHECMK_01189	1.83e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIKHECMK_01192	1.28e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIKHECMK_01193	9.02e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
IIKHECMK_01194	6.91e-233	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IIKHECMK_01195	6.44e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIKHECMK_01196	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
IIKHECMK_01197	1.56e-179	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IIKHECMK_01198	4.43e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIKHECMK_01199	4.69e-151	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
IIKHECMK_01200	4.06e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIKHECMK_01201	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IIKHECMK_01202	1.23e-89	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
IIKHECMK_01203	1.46e-17	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
IIKHECMK_01204	6.62e-179	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
IIKHECMK_01205	5.08e-158	-	-	-	S	-	-	-	tigr01906
IIKHECMK_01206	8.04e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIKHECMK_01207	7.79e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IIKHECMK_01208	2.21e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IIKHECMK_01212	3.31e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIKHECMK_01213	4.07e-144	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIKHECMK_01214	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIKHECMK_01215	1.45e-262	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
IIKHECMK_01216	2.15e-129	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
IIKHECMK_01217	3.75e-29	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
IIKHECMK_01218	1.15e-189	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIKHECMK_01219	1.82e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IIKHECMK_01220	1.66e-91	mesH	-	-	S	-	-	-	GtrA-like protein
IIKHECMK_01221	4.62e-316	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIKHECMK_01222	1.47e-217	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
IIKHECMK_01223	1.15e-160	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIKHECMK_01224	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
IIKHECMK_01225	1.02e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IIKHECMK_01226	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIKHECMK_01227	7.13e-168	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
IIKHECMK_01228	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
IIKHECMK_01229	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IIKHECMK_01230	9.56e-245	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IIKHECMK_01231	3.36e-27	-	6.3.2.2, 6.3.2.4	-	F	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	ko00000,ko00001,ko00002,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IIKHECMK_01232	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IIKHECMK_01233	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIKHECMK_01234	1.58e-50	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
IIKHECMK_01235	4.36e-284	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
IIKHECMK_01236	4.25e-271	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IIKHECMK_01237	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IIKHECMK_01238	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
IIKHECMK_01239	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIKHECMK_01240	8.44e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIKHECMK_01242	3.68e-97	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
IIKHECMK_01243	2.7e-86	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
IIKHECMK_01244	5.92e-213	ypuA	-	-	S	-	-	-	secreted protein
IIKHECMK_01245	1.48e-73	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 LactoylglutaTHIone lyase and related lyases
IIKHECMK_01246	3.97e-76	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IIKHECMK_01247	1.12e-78	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
IIKHECMK_01248	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIKHECMK_01249	2.06e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IIKHECMK_01250	0.0	noxE	-	-	P	-	-	-	NADH oxidase
IIKHECMK_01251	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
IIKHECMK_01252	7.55e-61	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIKHECMK_01253	5.36e-12	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIKHECMK_01254	7.8e-198	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
IIKHECMK_01255	1.46e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IIKHECMK_01257	1.21e-303	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIKHECMK_01258	4.59e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
IIKHECMK_01261	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIKHECMK_01262	1.07e-120	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIKHECMK_01263	1.75e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIKHECMK_01264	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IIKHECMK_01265	6.47e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIKHECMK_01266	3.12e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIKHECMK_01267	8.33e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIKHECMK_01268	4.29e-116	alkD	-	-	L	-	-	-	Dna alkylation repair
IIKHECMK_01269	8.82e-119	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
IIKHECMK_01270	1.68e-58	-	-	-	L	-	-	-	Transposase
IIKHECMK_01271	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIKHECMK_01272	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIKHECMK_01273	6.13e-165	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
IIKHECMK_01274	7.3e-85	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
IIKHECMK_01275	6.45e-124	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IIKHECMK_01276	1.1e-177	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01277	3.49e-217	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
IIKHECMK_01278	1.09e-143	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01279	0.0	-	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
IIKHECMK_01280	1.2e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
IIKHECMK_01281	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IIKHECMK_01282	8.06e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IIKHECMK_01283	2.03e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IIKHECMK_01285	2.06e-188	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IIKHECMK_01286	1.21e-128	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	transport system, permease component
IIKHECMK_01287	7.23e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIKHECMK_01288	1.75e-238	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_01289	8.66e-172	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
IIKHECMK_01290	1.52e-205	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01293	2.73e-213	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
IIKHECMK_01294	5.54e-105	-	-	-	F	-	-	-	cytidine deaminase activity
IIKHECMK_01295	6.33e-46	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
IIKHECMK_01296	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IIKHECMK_01297	3e-171	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IIKHECMK_01298	4.75e-220	-	-	-	T	-	-	-	Histidine kinase
IIKHECMK_01299	1.29e-159	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIKHECMK_01300	3.72e-87	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIKHECMK_01301	4.61e-97	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IIKHECMK_01302	9.96e-97	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
IIKHECMK_01303	3.14e-46	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IIKHECMK_01304	2.41e-315	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IIKHECMK_01305	2.01e-241	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIKHECMK_01306	2.09e-115	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_01307	1.9e-250	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase
IIKHECMK_01308	2.66e-118	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01309	8.13e-93	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01310	1.13e-74	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IIKHECMK_01311	3.99e-141	-	-	-	S	-	-	-	MmgE/PrpD family
IIKHECMK_01312	8.63e-120	ykrV3	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
IIKHECMK_01313	9.05e-30	ykrV3	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IIKHECMK_01314	1.61e-51	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
IIKHECMK_01315	3.03e-63	-	-	-	C	ko:K08317	-	ko00000,ko01000	glycerol dehydrogenase
IIKHECMK_01317	5.65e-231	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIKHECMK_01318	1.4e-299	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IIKHECMK_01319	1.39e-88	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIKHECMK_01320	1.4e-65	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIKHECMK_01321	3.31e-35	csbD	-	-	K	-	-	-	CsbD-like
IIKHECMK_01322	9.34e-09	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
IIKHECMK_01323	4.6e-294	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IIKHECMK_01324	2.85e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
IIKHECMK_01325	1.08e-118	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IIKHECMK_01326	2.96e-100	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
IIKHECMK_01327	1.84e-203	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IIKHECMK_01328	6.14e-297	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIKHECMK_01329	1.42e-143	ydgI	-	-	C	-	-	-	Nitroreductase
IIKHECMK_01330	9.58e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIKHECMK_01331	1.23e-06	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
IIKHECMK_01332	1.11e-203	yvgN	-	-	C	-	-	-	reductase
IIKHECMK_01333	7.36e-70	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIKHECMK_01334	4.11e-12	-	-	-	-	-	-	-	-
IIKHECMK_01335	1.68e-180	-	-	-	S	-	-	-	Abortive infection C-terminus
IIKHECMK_01336	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
IIKHECMK_01337	1.29e-158	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
IIKHECMK_01338	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
IIKHECMK_01340	1.58e-50	BP1961	-	-	P	-	-	-	nitric oxide dioxygenase activity
IIKHECMK_01341	7.28e-70	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IIKHECMK_01342	7.54e-83	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
IIKHECMK_01344	8.65e-81	-	-	-	-	-	-	-	-
IIKHECMK_01345	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIKHECMK_01346	1.69e-219	-	-	-	-	-	-	-	-
IIKHECMK_01347	1.08e-14	-	-	-	IQ	-	-	-	PFAM AMP-dependent synthetase and ligase
IIKHECMK_01349	4.88e-140	-	-	-	E	-	-	-	LysE type translocator
IIKHECMK_01350	3.23e-10	-	-	-	-	-	-	-	-
IIKHECMK_01351	1.96e-12	-	-	-	-	-	-	-	-
IIKHECMK_01352	0.0	-	-	-	M	-	-	-	family 8
IIKHECMK_01353	9.56e-14	-	-	-	-	-	-	-	-
IIKHECMK_01355	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
IIKHECMK_01356	2.27e-293	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIKHECMK_01357	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
IIKHECMK_01358	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
IIKHECMK_01359	1.69e-257	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
IIKHECMK_01360	6.03e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IIKHECMK_01361	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
IIKHECMK_01362	1.15e-282	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIKHECMK_01363	1.4e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IIKHECMK_01364	1.7e-13	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_01365	1.18e-34	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_01366	5.97e-253	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	translation initiation factor activity
IIKHECMK_01367	1.32e-97	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
IIKHECMK_01368	4.12e-98	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IIKHECMK_01369	1.49e-54	-	-	-	V	ko:K18996,ko:K19171	-	ko00000,ko02048,ko03032	(ABC) transporter
IIKHECMK_01370	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
IIKHECMK_01371	2.58e-113	-	-	-	L	-	-	-	Transposase
IIKHECMK_01372	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IIKHECMK_01373	2e-241	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IIKHECMK_01374	5.45e-172	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IIKHECMK_01375	6.44e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIKHECMK_01378	8.07e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIKHECMK_01379	4.58e-224	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IIKHECMK_01380	1.88e-155	yvqF	-	-	KT	ko:K11622	ko02020,map02020	ko00000,ko00001	membrane
IIKHECMK_01381	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IIKHECMK_01382	7.75e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IIKHECMK_01383	1.1e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIKHECMK_01384	1.55e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIKHECMK_01385	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIKHECMK_01386	6.79e-62	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
IIKHECMK_01387	1.51e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IIKHECMK_01388	1.39e-312	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIKHECMK_01389	2.05e-190	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
IIKHECMK_01390	1.57e-188	-	-	-	S	-	-	-	overlaps another CDS with the same product name
IIKHECMK_01391	3.45e-83	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
IIKHECMK_01392	1.23e-160	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01393	2.73e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
IIKHECMK_01394	3.46e-218	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_01395	8.41e-260	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_01396	2.01e-213	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01397	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01398	2.67e-178	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IIKHECMK_01399	1.44e-198	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IIKHECMK_01400	7.98e-17	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_01401	1.15e-245	-	-	-	L	ko:K07485	-	ko00000	Transposase
IIKHECMK_01402	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
IIKHECMK_01403	1.18e-60	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IIKHECMK_01404	8.42e-51	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
IIKHECMK_01405	3.41e-277	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IIKHECMK_01406	9.59e-141	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IIKHECMK_01407	2.04e-38	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_01408	2.9e-29	-	-	-	L	-	-	-	Transposase
IIKHECMK_01409	5.86e-52	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_01410	1.15e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IIKHECMK_01411	7.67e-222	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IIKHECMK_01412	1.19e-197	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIKHECMK_01413	5.61e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
IIKHECMK_01414	5.5e-134	yjbK	-	-	S	-	-	-	Adenylate cyclase
IIKHECMK_01415	2.07e-226	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIKHECMK_01416	1.12e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IIKHECMK_01417	1.77e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IIKHECMK_01418	9.11e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIKHECMK_01419	1.83e-166	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
IIKHECMK_01420	7.98e-155	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IIKHECMK_01421	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
IIKHECMK_01422	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
IIKHECMK_01423	0.0	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
IIKHECMK_01424	8.58e-291	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIKHECMK_01425	1.38e-184	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
IIKHECMK_01426	1.14e-226	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
IIKHECMK_01427	7.51e-285	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
IIKHECMK_01428	1.07e-134	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
IIKHECMK_01429	2.21e-63	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
IIKHECMK_01430	1.69e-161	-	-	-	S	-	-	-	Glycosyl transferase family 2
IIKHECMK_01431	4.19e-51	arnC	-	-	M	ko:K00786	-	ko00000,ko01000	group 2 family protein
IIKHECMK_01432	3.53e-178	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
IIKHECMK_01433	1.68e-277	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
IIKHECMK_01434	1.9e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIKHECMK_01435	1.37e-220	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
IIKHECMK_01436	4.86e-74	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
IIKHECMK_01437	3.03e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIKHECMK_01438	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIKHECMK_01439	3.51e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IIKHECMK_01440	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_01441	8.57e-177	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_01442	1.17e-268	arcT	-	-	E	-	-	-	Aminotransferase
IIKHECMK_01443	1.53e-175	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_01444	2.75e-184	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IIKHECMK_01445	1.45e-107	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
IIKHECMK_01446	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIKHECMK_01447	2.41e-74	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IIKHECMK_01448	1.27e-39	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
IIKHECMK_01449	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
IIKHECMK_01450	7.15e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01451	1.84e-24	XK27_00735	-	-	-	-	-	-	-
IIKHECMK_01452	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIKHECMK_01453	8.41e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
IIKHECMK_01454	6.36e-173	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IIKHECMK_01457	3.48e-140	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
IIKHECMK_01458	4.33e-69	-	-	-	V	-	-	-	Psort location Cytoplasmic, score
IIKHECMK_01459	4.34e-202	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
IIKHECMK_01460	0.0	-	-	-	C	ko:K06871	-	ko00000	Arylsulfatase regulator (Fe-S oxidoreductase)
IIKHECMK_01461	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
IIKHECMK_01463	3.11e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4299)
IIKHECMK_01464	1.25e-85	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
IIKHECMK_01465	2.2e-195	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
IIKHECMK_01467	1.69e-145	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
IIKHECMK_01468	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIKHECMK_01469	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIKHECMK_01470	1.07e-141	-	-	-	S	-	-	-	IA, variant 1
IIKHECMK_01471	4.46e-151	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	effector of murein hydrolase
IIKHECMK_01472	5.26e-77	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
IIKHECMK_01474	2.92e-78	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IIKHECMK_01475	3.47e-72	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
IIKHECMK_01476	2.61e-281	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIKHECMK_01477	5.63e-136	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
IIKHECMK_01478	3.61e-267	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIKHECMK_01479	1.7e-149	-	-	-	GK	-	-	-	ROK family
IIKHECMK_01480	1.61e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
IIKHECMK_01481	2.63e-157	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
IIKHECMK_01482	1.85e-05	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
IIKHECMK_01483	6.65e-261	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
IIKHECMK_01484	2.09e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
IIKHECMK_01485	1.15e-178	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
IIKHECMK_01486	7.96e-272	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIKHECMK_01487	3.1e-219	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IIKHECMK_01488	1.13e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IIKHECMK_01489	1.05e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIKHECMK_01490	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IIKHECMK_01491	1.29e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IIKHECMK_01492	1.17e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
IIKHECMK_01493	0.0	ydaO	-	-	E	-	-	-	amino acid
IIKHECMK_01494	2.35e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IIKHECMK_01495	9.09e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IIKHECMK_01496	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IIKHECMK_01497	5.38e-219	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
IIKHECMK_01498	2.43e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IIKHECMK_01499	1.22e-97	-	-	-	S	-	-	-	QueT transporter
IIKHECMK_01500	2.33e-155	-	-	-	L	-	-	-	Transposase DDE domain
IIKHECMK_01501	3.86e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIKHECMK_01502	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIKHECMK_01503	2.79e-111	ccl	-	-	S	-	-	-	cog cog4708
IIKHECMK_01504	2.35e-205	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IIKHECMK_01505	2.86e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IIKHECMK_01506	6.58e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IIKHECMK_01507	5.58e-126	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
IIKHECMK_01508	2.59e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIKHECMK_01509	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IIKHECMK_01510	4.12e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IIKHECMK_01511	1.76e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IIKHECMK_01512	3.54e-117	nodB3	-	-	G	-	-	-	polysaccharide deacetylase
IIKHECMK_01513	7.67e-66	nodB3	-	-	G	-	-	-	polysaccharide deacetylase
IIKHECMK_01514	6.12e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
IIKHECMK_01515	4.12e-56	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IIKHECMK_01516	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIKHECMK_01517	6.14e-205	corA	-	-	P	-	-	-	CorA-like protein
IIKHECMK_01518	1.07e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
IIKHECMK_01519	4.57e-129	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
IIKHECMK_01520	2.62e-203	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
IIKHECMK_01521	3.13e-257	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
IIKHECMK_01522	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIKHECMK_01523	1.15e-155	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
IIKHECMK_01524	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIKHECMK_01527	9.46e-200	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IIKHECMK_01528	2.01e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01529	1.4e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01530	8.58e-149	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01531	1.12e-246	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IIKHECMK_01532	9.48e-43	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
IIKHECMK_01533	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IIKHECMK_01534	3.66e-98	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
IIKHECMK_01535	1.23e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIKHECMK_01536	2.76e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIKHECMK_01537	3.9e-131	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
IIKHECMK_01538	7.94e-173	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IIKHECMK_01539	1.1e-230	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIKHECMK_01540	2.47e-136	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
IIKHECMK_01541	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIKHECMK_01542	3.63e-57	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
IIKHECMK_01543	1.25e-74	-	-	-	-	-	-	-	-
IIKHECMK_01544	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IIKHECMK_01545	3.83e-35	-	-	-	-	-	-	-	-
IIKHECMK_01546	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIKHECMK_01547	2.2e-61	-	-	-	L	-	-	-	transposase activity
IIKHECMK_01548	5.63e-148	-	-	-	K	-	-	-	transcriptional regulator, MerR family
IIKHECMK_01549	1.31e-135	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IIKHECMK_01550	1.41e-80	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
IIKHECMK_01551	1.23e-82	XK27_02560	-	-	S	-	-	-	cog cog2151
IIKHECMK_01552	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
IIKHECMK_01553	3.35e-289	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
IIKHECMK_01555	4.36e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIKHECMK_01556	6.95e-196	ytmP	-	-	M	-	-	-	Phosphotransferase
IIKHECMK_01557	2.57e-230	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IIKHECMK_01558	1.5e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01559	2.93e-93	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IIKHECMK_01560	2.23e-13	-	-	-	-	-	-	-	-
IIKHECMK_01561	4.85e-143	-	-	-	-	-	-	-	-
IIKHECMK_01563	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
IIKHECMK_01564	1.46e-261	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IIKHECMK_01565	3.24e-178	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
IIKHECMK_01566	9.81e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIKHECMK_01567	2.01e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IIKHECMK_01568	1.11e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIKHECMK_01569	1.59e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
IIKHECMK_01570	2.78e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IIKHECMK_01571	1.84e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IIKHECMK_01572	8.57e-197	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIKHECMK_01573	1.02e-85	-	-	-	-	-	-	-	-
IIKHECMK_01574	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIKHECMK_01575	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIKHECMK_01576	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIKHECMK_01577	4.51e-35	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
IIKHECMK_01578	3.8e-43	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
IIKHECMK_01579	1.85e-120	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IIKHECMK_01580	1.12e-190	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IIKHECMK_01581	2.29e-124	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIKHECMK_01582	3.83e-196	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IIKHECMK_01583	3.02e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
IIKHECMK_01584	6.34e-182	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IIKHECMK_01585	3.71e-303	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IIKHECMK_01586	7.54e-99	XK27_03180	-	-	T	-	-	-	universal stress protein
IIKHECMK_01588	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIKHECMK_01589	2.02e-304	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
IIKHECMK_01590	1.29e-185	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01591	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
IIKHECMK_01593	1.82e-126	mraW1	-	-	J	-	-	-	(SAM)-dependent
IIKHECMK_01594	1.51e-236	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
IIKHECMK_01595	1.61e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IIKHECMK_01596	7.91e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIKHECMK_01597	9.01e-121	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IIKHECMK_01598	4.78e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIKHECMK_01599	2.82e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
IIKHECMK_01600	3.38e-170	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
IIKHECMK_01601	1.37e-221	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
IIKHECMK_01602	1.12e-191	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIKHECMK_01604	8.1e-261	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIKHECMK_01605	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
IIKHECMK_01606	1.35e-156	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
IIKHECMK_01607	1.49e-48	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIKHECMK_01608	5.76e-44	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIKHECMK_01609	2.05e-59	hsdS_1	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
IIKHECMK_01610	7.75e-44	-	-	-	D	-	-	-	nuclear chromosome segregation
IIKHECMK_01611	6.36e-105	-	-	-	L	ko:K04763	-	ko00000,ko03036	DNA integration
IIKHECMK_01612	3.03e-159	XK27_05540	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
IIKHECMK_01613	7e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IIKHECMK_01614	6.9e-150	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01615	2.76e-42	-	-	-	-	-	-	-	-
IIKHECMK_01616	1.19e-234	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
IIKHECMK_01617	6.61e-179	cppA	-	-	E	-	-	-	CppA N-terminal
IIKHECMK_01618	6.33e-233	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives IS30 family
IIKHECMK_01619	3.74e-38	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IIKHECMK_01620	7.59e-212	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IIKHECMK_01621	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIKHECMK_01623	1.03e-111	-	-	-	L	-	-	-	Transposase
IIKHECMK_01624	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
IIKHECMK_01626	3.68e-172	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
IIKHECMK_01627	1.03e-301	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
IIKHECMK_01629	1.9e-203	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIKHECMK_01630	2.57e-67	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIKHECMK_01631	0.0	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIKHECMK_01632	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01633	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01635	1.34e-120	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
IIKHECMK_01636	1.36e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IIKHECMK_01637	2.44e-139	yutD	-	-	J	-	-	-	protein conserved in bacteria
IIKHECMK_01638	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IIKHECMK_01640	5.56e-304	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIKHECMK_01641	8.08e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIKHECMK_01642	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
IIKHECMK_01643	5.53e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
IIKHECMK_01644	2.67e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIKHECMK_01645	1.25e-68	-	-	-	-	-	-	-	-
IIKHECMK_01646	1.93e-28	-	-	-	-	-	-	-	-
IIKHECMK_01647	8.59e-54	-	-	-	-	-	-	-	-
IIKHECMK_01648	4.29e-40	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
IIKHECMK_01649	1.12e-28	-	-	-	D	-	-	-	nuclear chromosome segregation
IIKHECMK_01650	2.11e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIKHECMK_01651	2.47e-182	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIKHECMK_01652	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
IIKHECMK_01653	4.4e-117	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
IIKHECMK_01654	1.92e-60	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
IIKHECMK_01655	3.67e-137	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IIKHECMK_01656	6.65e-15	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IIKHECMK_01657	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IIKHECMK_01658	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IIKHECMK_01659	2.54e-84	-	-	-	S	-	-	-	membrane
IIKHECMK_01660	3.34e-14	XK27_02470	-	-	K	-	-	-	LytTr DNA-binding domain protein
IIKHECMK_01661	3.89e-82	-	-	-	KT	-	-	-	response to antibiotic
IIKHECMK_01662	6.48e-22	-	-	-	KT	-	-	-	response to antibiotic
IIKHECMK_01663	2.11e-127	yebC	-	-	M	-	-	-	Membrane
IIKHECMK_01664	4.77e-24	yebC	-	-	M	-	-	-	Membrane
IIKHECMK_01665	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
IIKHECMK_01666	7.77e-234	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IIKHECMK_01667	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIKHECMK_01668	1.92e-243	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIKHECMK_01669	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIKHECMK_01670	1.32e-247	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IIKHECMK_01671	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIKHECMK_01673	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IIKHECMK_01674	2.77e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
IIKHECMK_01675	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
IIKHECMK_01676	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IIKHECMK_01677	2.63e-44	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	purine nucleotide biosynthetic process
IIKHECMK_01678	3.61e-143	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional
IIKHECMK_01679	2.67e-96	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIKHECMK_01680	9.01e-81	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
IIKHECMK_01681	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIKHECMK_01682	1.43e-109	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IIKHECMK_01683	5.88e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
IIKHECMK_01686	7.27e-57	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
IIKHECMK_01687	2.97e-46	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
IIKHECMK_01690	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IIKHECMK_01691	3.48e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
IIKHECMK_01692	5.91e-159	-	-	-	S	-	-	-	Pfam PF06570
IIKHECMK_01694	2.03e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIKHECMK_01695	2.07e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIKHECMK_01696	3.11e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IIKHECMK_01698	3.72e-35	XK27_05745	-	-	-	-	-	-	-
IIKHECMK_01699	9.59e-293	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
IIKHECMK_01703	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIKHECMK_01704	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIKHECMK_01705	9.72e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
IIKHECMK_01706	5.78e-19	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIKHECMK_01707	1.91e-205	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIKHECMK_01708	3.19e-146	spi	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IIKHECMK_01709	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIKHECMK_01710	1.91e-63	azlD	-	-	E	-	-	-	branched-chain amino acid
IIKHECMK_01711	7.55e-150	XK27_12120	-	-	E	-	-	-	AzlC protein
IIKHECMK_01712	1.64e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIKHECMK_01713	1.54e-96	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIKHECMK_01714	2.39e-156	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
IIKHECMK_01715	6.45e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IIKHECMK_01716	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIKHECMK_01717	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IIKHECMK_01718	1.12e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
IIKHECMK_01719	1.53e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IIKHECMK_01720	4.89e-48	-	-	-	L	-	-	-	Transposase
IIKHECMK_01721	1.35e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IIKHECMK_01722	1.23e-56	-	-	-	L	ko:K07491	-	ko00000	Transposase
IIKHECMK_01723	3.83e-61	-	-	-	L	ko:K07483	-	ko00000	transposase activity
IIKHECMK_01724	1.45e-29	-	-	-	L	-	-	-	Transposase
IIKHECMK_01725	1.73e-70	-	-	-	L	ko:K07497	-	ko00000	transposition
IIKHECMK_01726	2.37e-110	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
IIKHECMK_01727	7.74e-241	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIKHECMK_01728	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIKHECMK_01729	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIKHECMK_01730	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIKHECMK_01731	7.65e-185	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
IIKHECMK_01732	1.13e-227	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
IIKHECMK_01733	4.63e-236	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
IIKHECMK_01734	1.92e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IIKHECMK_01735	2.76e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IIKHECMK_01736	5.55e-211	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIKHECMK_01738	1.06e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIKHECMK_01739	1.81e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIKHECMK_01740	4.49e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
IIKHECMK_01741	8.04e-99	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IIKHECMK_01742	5.36e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IIKHECMK_01743	5.24e-185	-	-	-	S	-	-	-	Macro domain protein
IIKHECMK_01744	3.24e-14	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
IIKHECMK_01745	3.95e-71	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
IIKHECMK_01748	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIKHECMK_01749	1.76e-114	-	-	-	L	ko:K07491	-	ko00000	Transposase
IIKHECMK_01750	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
IIKHECMK_01751	1.19e-237	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
IIKHECMK_01752	1.8e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIKHECMK_01753	7.08e-74	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIKHECMK_01754	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
IIKHECMK_01755	3.19e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIKHECMK_01756	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIKHECMK_01757	1.28e-107	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IIKHECMK_01758	1.56e-98	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IIKHECMK_01759	1.66e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIKHECMK_01760	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIKHECMK_01761	3.28e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IIKHECMK_01762	9.62e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IIKHECMK_01763	2.42e-49	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IIKHECMK_01764	3.23e-16	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IIKHECMK_01765	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIKHECMK_01766	2.98e-104	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IIKHECMK_01767	1.42e-85	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
IIKHECMK_01768	4.15e-46	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
IIKHECMK_01769	1.79e-46	XK27_09615	-	-	S	-	-	-	FMN reductase (NADPH) activity
IIKHECMK_01770	2.68e-171	-	-	-	S	-	-	-	PAS domain
IIKHECMK_01771	7.8e-11	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
IIKHECMK_01772	2.99e-83	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
IIKHECMK_01773	9.39e-83	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
IIKHECMK_01774	7.25e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IIKHECMK_01775	1.95e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IIKHECMK_01776	5.64e-153	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IIKHECMK_01777	4.01e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIKHECMK_01778	2.31e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIKHECMK_01779	6.92e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIKHECMK_01780	9.35e-64	-	-	-	S	ko:K07025	-	ko00000	glycolate biosynthetic process
IIKHECMK_01781	9.2e-87	-	-	-	S	ko:K07025	-	ko00000	phosphatase activity
IIKHECMK_01782	3.45e-203	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
IIKHECMK_01784	1.7e-117	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIKHECMK_01785	3.13e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIKHECMK_01786	3.2e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
IIKHECMK_01787	2.09e-244	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
IIKHECMK_01788	9.14e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIKHECMK_01789	3.48e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
IIKHECMK_01791	6.4e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IIKHECMK_01792	1.17e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIKHECMK_01793	3.37e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
IIKHECMK_01795	9.58e-88	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
IIKHECMK_01796	1.18e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
IIKHECMK_01797	4.85e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIKHECMK_01798	2.04e-227	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IIKHECMK_01799	5.13e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IIKHECMK_01800	2.56e-94	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
IIKHECMK_01801	3.66e-21	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
IIKHECMK_01802	1.03e-75	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
IIKHECMK_01803	2.23e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IIKHECMK_01804	6.09e-194	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IIKHECMK_01805	2.3e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IIKHECMK_01806	3.93e-91	-	-	-	S	-	-	-	cog cog4699
IIKHECMK_01807	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIKHECMK_01808	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIKHECMK_01809	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IIKHECMK_01810	1.01e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIKHECMK_01811	1.88e-250	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IIKHECMK_01812	2.89e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IIKHECMK_01813	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IIKHECMK_01814	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IIKHECMK_01815	1.57e-11	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IIKHECMK_01816	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IIKHECMK_01817	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
IIKHECMK_01818	7.9e-288	norN	-	-	V	-	-	-	Mate efflux family protein
IIKHECMK_01819	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IIKHECMK_01820	7.42e-74	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IIKHECMK_01821	3.04e-48	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
IIKHECMK_01822	1.16e-100	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IIKHECMK_01823	5.62e-132	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
IIKHECMK_01824	2.89e-87	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
IIKHECMK_01825	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IIKHECMK_01826	3.27e-155	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IIKHECMK_01827	2.49e-88	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IIKHECMK_01828	4.42e-75	treB	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS System
IIKHECMK_01829	2.66e-29	treR	-	-	K	ko:K03486,ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
IIKHECMK_01830	7.91e-115	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
IIKHECMK_01831	2.35e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IIKHECMK_01834	7.69e-18	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIKHECMK_01835	1.64e-98	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIKHECMK_01836	9.95e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
IIKHECMK_01838	7.87e-144	-	6.3.2.2	-	H	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	ergothioneine biosynthetic process
IIKHECMK_01839	2.3e-20	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
IIKHECMK_01840	6.82e-16	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
IIKHECMK_01841	1.14e-40	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIKHECMK_01842	4.9e-100	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
IIKHECMK_01843	2.13e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
IIKHECMK_01844	5.37e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIKHECMK_01845	1.57e-80	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIKHECMK_01846	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIKHECMK_01847	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IIKHECMK_01848	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIKHECMK_01849	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIKHECMK_01850	3.68e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIKHECMK_01851	3.45e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IIKHECMK_01852	2e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
IIKHECMK_01853	9.94e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIKHECMK_01854	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIKHECMK_01855	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIKHECMK_01856	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIKHECMK_01857	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIKHECMK_01858	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIKHECMK_01859	3.99e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIKHECMK_01860	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIKHECMK_01861	7.55e-53	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIKHECMK_01862	4.36e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IIKHECMK_01863	3.58e-93	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIKHECMK_01864	1.1e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIKHECMK_01865	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIKHECMK_01866	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIKHECMK_01867	7.19e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIKHECMK_01868	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIKHECMK_01869	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IIKHECMK_01870	2.23e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIKHECMK_01871	7.13e-63	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IIKHECMK_01872	1.78e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIKHECMK_01873	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
IIKHECMK_01874	2.43e-47	-	-	-	S	-	-	-	MORN repeat protein
IIKHECMK_01875	3.25e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIKHECMK_01876	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIKHECMK_01877	3.59e-123	flaR	-	-	F	-	-	-	topology modulation protein
IIKHECMK_01878	3.14e-244	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IIKHECMK_01879	3.96e-253	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
IIKHECMK_01880	3.2e-68	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_01881	5.63e-188	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IIKHECMK_01883	7.46e-200	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
IIKHECMK_01884	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
IIKHECMK_01885	1.81e-40	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
IIKHECMK_01886	2.28e-302	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
IIKHECMK_01887	2.51e-17	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
IIKHECMK_01888	8.05e-166	Z012_04635	-	-	K	-	-	-	sequence-specific DNA binding
IIKHECMK_01890	1.15e-296	-	-	-	C	ko:K06871	-	ko00000	Radical SAM
IIKHECMK_01891	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
IIKHECMK_01892	2.28e-207	-	-	-	L	-	-	-	Replication initiation factor
IIKHECMK_01893	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
IIKHECMK_01894	8.68e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IIKHECMK_01896	3.74e-303	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
IIKHECMK_01897	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IIKHECMK_01898	4.83e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IIKHECMK_01899	2.06e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIKHECMK_01900	2.22e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IIKHECMK_01901	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IIKHECMK_01902	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IIKHECMK_01903	7.68e-20	-	-	-	-	-	-	-	-
IIKHECMK_01904	1.87e-118	-	-	-	K	-	-	-	acetyltransferase
IIKHECMK_01905	2.18e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIKHECMK_01906	9.38e-187	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IIKHECMK_01907	5.33e-216	XK27_01785	-	-	S	-	-	-	cog cog1284
IIKHECMK_01908	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIKHECMK_01910	4.78e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IIKHECMK_01911	3.8e-174	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IIKHECMK_01912	2.42e-45	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IIKHECMK_01913	4.33e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IIKHECMK_01914	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IIKHECMK_01917	3.77e-68	yegS	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	lipid kinase activity
IIKHECMK_01918	1.25e-125	-	-	-	S	-	-	-	Hydrophobic domain protein
IIKHECMK_01920	1.61e-44	ytgB	-	-	S	-	-	-	Membrane
IIKHECMK_01921	1.32e-131	-	-	-	-	-	-	-	-
IIKHECMK_01922	7.53e-33	-	-	-	S	-	-	-	Small integral membrane protein
IIKHECMK_01923	1.31e-116	-	-	-	M	-	-	-	Protein conserved in bacteria
IIKHECMK_01924	1.49e-28	-	-	-	K	-	-	-	CsbD-like
IIKHECMK_01925	9.38e-134	XK27_06885	-	-	L	-	-	-	hydrolase
IIKHECMK_01926	2.9e-18	XK27_06885	-	-	L	-	-	-	hydrolase
IIKHECMK_01927	1.3e-26	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
IIKHECMK_01928	7.45e-34	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
IIKHECMK_01929	1.17e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
IIKHECMK_01930	1e-147	-	-	-	S	-	-	-	Putative adhesin
IIKHECMK_01931	8.83e-266	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
IIKHECMK_01932	3.98e-124	XK27_06935	-	-	K	-	-	-	transcriptional regulator
IIKHECMK_01933	7.97e-73	ypaA	-	-	S	ko:K08987	-	ko00000	membrane
IIKHECMK_01934	2.05e-09	-	-	-	-	-	-	-	-
IIKHECMK_01935	5.92e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIKHECMK_01936	3.05e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
IIKHECMK_01937	1.29e-312	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IIKHECMK_01938	2.86e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IIKHECMK_01939	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IIKHECMK_01940	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIKHECMK_01941	1.62e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIKHECMK_01942	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IIKHECMK_01943	9.5e-124	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
IIKHECMK_01944	1.37e-122	lytE	-	-	M	-	-	-	LysM domain protein
IIKHECMK_01945	2.56e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIKHECMK_01946	2.6e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIKHECMK_01947	4.68e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIKHECMK_01948	1.55e-117	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIKHECMK_01949	3.09e-185	ymfM	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
IIKHECMK_01950	6.27e-308	ymfH	-	-	S	-	-	-	Peptidase M16
IIKHECMK_01951	5.28e-300	albE	-	-	S	-	-	-	Peptidase M16
IIKHECMK_01952	3.7e-69	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
IIKHECMK_01953	2.24e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIKHECMK_01954	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IIKHECMK_01955	1.17e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IIKHECMK_01956	3.96e-195	XK27_10395	-	-	S	-	-	-	membrane
IIKHECMK_01957	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
IIKHECMK_01958	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
IIKHECMK_01962	3.66e-155	yveI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IIKHECMK_01963	1.79e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIKHECMK_01964	3.59e-268	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IIKHECMK_01965	3.94e-173	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family