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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PNEFGJKF_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PNEFGJKF_00002	8.49e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PNEFGJKF_00003	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PNEFGJKF_00004	2.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PNEFGJKF_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNEFGJKF_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNEFGJKF_00007	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PNEFGJKF_00008	1.03e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PNEFGJKF_00009	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PNEFGJKF_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PNEFGJKF_00011	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PNEFGJKF_00012	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PNEFGJKF_00013	3.37e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_00014	1.56e-80	-	-	-	-	-	-	-	-
PNEFGJKF_00015	1.36e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
PNEFGJKF_00016	5.2e-132	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PNEFGJKF_00018	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PNEFGJKF_00019	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PNEFGJKF_00021	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PNEFGJKF_00022	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNEFGJKF_00023	0.0	yycH	-	-	S	-	-	-	YycH protein
PNEFGJKF_00024	6.38e-196	yycI	-	-	S	-	-	-	YycH protein
PNEFGJKF_00025	3.06e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PNEFGJKF_00026	6.24e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PNEFGJKF_00027	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
PNEFGJKF_00028	1.02e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PNEFGJKF_00029	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PNEFGJKF_00031	1.56e-125	-	-	-	S	-	-	-	reductase
PNEFGJKF_00032	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
PNEFGJKF_00033	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PNEFGJKF_00034	3.72e-193	-	-	-	E	-	-	-	Glyoxalase-like domain
PNEFGJKF_00035	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNEFGJKF_00036	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PNEFGJKF_00037	1.06e-202	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PNEFGJKF_00038	1.69e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PNEFGJKF_00039	3.16e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PNEFGJKF_00041	7.63e-64	-	-	-	-	-	-	-	-
PNEFGJKF_00042	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PNEFGJKF_00045	1.37e-35	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PNEFGJKF_00046	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
PNEFGJKF_00047	5.24e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEFGJKF_00048	2.83e-282	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNEFGJKF_00049	8.68e-44	-	-	-	-	-	-	-	-
PNEFGJKF_00050	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
PNEFGJKF_00052	1.22e-139	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PNEFGJKF_00053	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNEFGJKF_00054	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PNEFGJKF_00055	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PNEFGJKF_00056	9.34e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
PNEFGJKF_00057	4.84e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PNEFGJKF_00058	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PNEFGJKF_00059	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PNEFGJKF_00060	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PNEFGJKF_00061	8.58e-94	-	-	-	-	-	-	-	-
PNEFGJKF_00062	7.34e-27	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PNEFGJKF_00063	1.55e-73	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PNEFGJKF_00064	1.1e-153	dltr	-	-	K	-	-	-	response regulator
PNEFGJKF_00065	5.59e-290	sptS	-	-	T	-	-	-	Histidine kinase
PNEFGJKF_00066	7.76e-279	-	-	-	P	-	-	-	Voltage gated chloride channel
PNEFGJKF_00067	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PNEFGJKF_00068	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00069	1.29e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PNEFGJKF_00070	1.54e-216	-	-	-	C	-	-	-	Aldo keto reductase
PNEFGJKF_00071	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PNEFGJKF_00072	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PNEFGJKF_00073	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PNEFGJKF_00074	2.95e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PNEFGJKF_00075	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PNEFGJKF_00076	2.31e-131	-	-	-	-	-	-	-	-
PNEFGJKF_00077	1.14e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PNEFGJKF_00079	3.62e-308	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_00080	4.72e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PNEFGJKF_00081	8.71e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PNEFGJKF_00082	5.46e-315	-	-	-	E	-	-	-	amino acid
PNEFGJKF_00083	1.64e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PNEFGJKF_00084	4.39e-94	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PNEFGJKF_00085	8.53e-95	-	-	-	-	-	-	-	-
PNEFGJKF_00086	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PNEFGJKF_00087	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
PNEFGJKF_00088	0.0	-	-	-	M	-	-	-	domain protein
PNEFGJKF_00089	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PNEFGJKF_00090	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PNEFGJKF_00091	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PNEFGJKF_00092	3.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PNEFGJKF_00093	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PNEFGJKF_00094	2.07e-236	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
PNEFGJKF_00095	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNEFGJKF_00097	6e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PNEFGJKF_00098	3e-274	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PNEFGJKF_00099	2.4e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PNEFGJKF_00100	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_00101	8.5e-266	-	-	-	M	-	-	-	Rib/alpha-like repeat
PNEFGJKF_00102	9.62e-94	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_00103	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PNEFGJKF_00104	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PNEFGJKF_00105	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNEFGJKF_00106	3.99e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00107	2.25e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PNEFGJKF_00108	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
PNEFGJKF_00109	2.47e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PNEFGJKF_00110	1.08e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
PNEFGJKF_00111	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PNEFGJKF_00112	3.57e-198	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PNEFGJKF_00113	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PNEFGJKF_00114	1.68e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PNEFGJKF_00115	8.24e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PNEFGJKF_00116	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PNEFGJKF_00117	6.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PNEFGJKF_00118	5.64e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PNEFGJKF_00119	6.87e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PNEFGJKF_00120	5.15e-306	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
PNEFGJKF_00121	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PNEFGJKF_00122	5.59e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
PNEFGJKF_00123	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PNEFGJKF_00124	9.76e-161	vanR	-	-	K	-	-	-	response regulator
PNEFGJKF_00125	1.36e-266	hpk31	-	-	T	-	-	-	Histidine kinase
PNEFGJKF_00126	6.03e-196	-	-	-	E	-	-	-	AzlC protein
PNEFGJKF_00127	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
PNEFGJKF_00128	1.3e-156	-	-	-	K	ko:K09681	-	ko00000,ko03000	DNA-binding transcription factor activity
PNEFGJKF_00129	1.56e-20	-	-	-	K	-	-	-	LysR substrate binding domain
PNEFGJKF_00130	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PNEFGJKF_00131	3.19e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PNEFGJKF_00132	2.77e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PNEFGJKF_00133	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PNEFGJKF_00134	6.66e-151	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PNEFGJKF_00135	1.4e-152	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PNEFGJKF_00136	1.4e-302	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PNEFGJKF_00137	5.53e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
PNEFGJKF_00138	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PNEFGJKF_00139	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PNEFGJKF_00140	4.32e-173	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
PNEFGJKF_00141	8.95e-110	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PNEFGJKF_00142	1.75e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PNEFGJKF_00143	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PNEFGJKF_00144	2.7e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PNEFGJKF_00145	1.34e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEFGJKF_00146	1.19e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEFGJKF_00147	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEFGJKF_00148	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PNEFGJKF_00149	8.29e-252	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PNEFGJKF_00150	4.09e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PNEFGJKF_00151	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PNEFGJKF_00152	4.44e-314	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PNEFGJKF_00153	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PNEFGJKF_00154	4.86e-237	-	-	-	-	-	-	-	-
PNEFGJKF_00155	2.97e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PNEFGJKF_00158	1.5e-85	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNEFGJKF_00159	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_00161	3.87e-112	-	-	-	-	-	-	-	-
PNEFGJKF_00162	6.73e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_00163	1.69e-170	-	-	-	F	-	-	-	NUDIX domain
PNEFGJKF_00164	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNEFGJKF_00165	3.53e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
PNEFGJKF_00166	2.34e-266	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PNEFGJKF_00167	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
PNEFGJKF_00168	2.09e-213	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
PNEFGJKF_00169	1.07e-52	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
PNEFGJKF_00170	1.05e-309	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
PNEFGJKF_00171	1.89e-171	-	-	-	IQ	-	-	-	dehydrogenase reductase
PNEFGJKF_00172	2.33e-51	-	-	-	-	-	-	-	-
PNEFGJKF_00173	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PNEFGJKF_00174	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
PNEFGJKF_00175	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PNEFGJKF_00176	1.86e-136	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNEFGJKF_00177	1.2e-63	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNEFGJKF_00179	3.04e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
PNEFGJKF_00180	6.25e-83	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PNEFGJKF_00181	6.12e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PNEFGJKF_00183	3.04e-233	ydhF	-	-	S	-	-	-	Aldo keto reductase
PNEFGJKF_00184	1.31e-109	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
PNEFGJKF_00185	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PNEFGJKF_00187	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PNEFGJKF_00188	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PNEFGJKF_00189	2.31e-166	-	-	-	-	-	-	-	-
PNEFGJKF_00190	3e-167	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PNEFGJKF_00191	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PNEFGJKF_00192	5.8e-291	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
PNEFGJKF_00193	4.44e-11	-	-	-	-	-	-	-	-
PNEFGJKF_00194	5.1e-204	-	-	-	GM	-	-	-	NAD(P)H-binding
PNEFGJKF_00195	1.07e-68	ywnA	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_00196	1.85e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
PNEFGJKF_00197	2.86e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_00198	6.38e-184	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00199	6.84e-139	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
PNEFGJKF_00200	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PNEFGJKF_00201	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PNEFGJKF_00202	6.12e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PNEFGJKF_00203	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_00204	1.04e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PNEFGJKF_00205	5.28e-201	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PNEFGJKF_00206	1.26e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PNEFGJKF_00207	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
PNEFGJKF_00208	3.07e-58	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
PNEFGJKF_00209	4.89e-153	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PNEFGJKF_00210	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PNEFGJKF_00211	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PNEFGJKF_00213	1.1e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PNEFGJKF_00214	0.0	-	-	-	L	-	-	-	DNA helicase
PNEFGJKF_00215	2.02e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PNEFGJKF_00216	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
PNEFGJKF_00217	1.36e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PNEFGJKF_00218	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PNEFGJKF_00219	1.98e-297	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PNEFGJKF_00220	1.33e-228	-	-	-	-	-	-	-	-
PNEFGJKF_00221	1.51e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PNEFGJKF_00223	1.16e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PNEFGJKF_00224	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PNEFGJKF_00225	5.77e-201	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PNEFGJKF_00226	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PNEFGJKF_00227	3.73e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PNEFGJKF_00228	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PNEFGJKF_00229	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PNEFGJKF_00230	5.16e-218	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PNEFGJKF_00231	4.85e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PNEFGJKF_00232	4.31e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
PNEFGJKF_00233	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PNEFGJKF_00234	2.74e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PNEFGJKF_00235	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PNEFGJKF_00236	2.4e-102	-	-	-	-	-	-	-	-
PNEFGJKF_00237	2.06e-193	yidA	-	-	S	-	-	-	hydrolase
PNEFGJKF_00238	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PNEFGJKF_00239	2.16e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PNEFGJKF_00240	1.2e-80	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00241	1.54e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_00242	1.95e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PNEFGJKF_00243	3.49e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PNEFGJKF_00244	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PNEFGJKF_00245	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_00246	6.72e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNEFGJKF_00247	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PNEFGJKF_00248	2.02e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNEFGJKF_00249	8.23e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PNEFGJKF_00250	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PNEFGJKF_00251	3.01e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PNEFGJKF_00252	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PNEFGJKF_00253	1.84e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PNEFGJKF_00254	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PNEFGJKF_00255	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PNEFGJKF_00256	1.84e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PNEFGJKF_00257	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PNEFGJKF_00258	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PNEFGJKF_00259	4.68e-197	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PNEFGJKF_00260	6.14e-215	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PNEFGJKF_00261	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00262	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_00263	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PNEFGJKF_00264	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEFGJKF_00265	3.3e-302	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PNEFGJKF_00266	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEFGJKF_00267	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PNEFGJKF_00268	2.29e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PNEFGJKF_00269	2.28e-271	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PNEFGJKF_00270	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PNEFGJKF_00271	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PNEFGJKF_00272	9.6e-310	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
PNEFGJKF_00273	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PNEFGJKF_00274	8.08e-147	-	-	-	S	-	-	-	(CBS) domain
PNEFGJKF_00275	1.38e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PNEFGJKF_00276	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PNEFGJKF_00277	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
PNEFGJKF_00278	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PNEFGJKF_00279	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PNEFGJKF_00280	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PNEFGJKF_00281	1.05e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PNEFGJKF_00282	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PNEFGJKF_00283	2.77e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PNEFGJKF_00284	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PNEFGJKF_00285	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PNEFGJKF_00286	6.85e-115	-	-	-	-	-	-	-	-
PNEFGJKF_00290	2.21e-87	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNEFGJKF_00291	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_00294	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PNEFGJKF_00295	2.01e-206	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PNEFGJKF_00298	5.92e-150	-	-	-	-	-	-	-	-
PNEFGJKF_00299	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_00300	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PNEFGJKF_00301	5.9e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PNEFGJKF_00302	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PNEFGJKF_00303	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNEFGJKF_00304	1.84e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PNEFGJKF_00305	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PNEFGJKF_00306	2e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PNEFGJKF_00308	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PNEFGJKF_00309	9.89e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PNEFGJKF_00310	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PNEFGJKF_00311	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PNEFGJKF_00312	7.63e-217	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PNEFGJKF_00313	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PNEFGJKF_00314	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNEFGJKF_00315	1.75e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00316	3.01e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PNEFGJKF_00317	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PNEFGJKF_00318	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PNEFGJKF_00319	1.65e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PNEFGJKF_00320	1.02e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PNEFGJKF_00321	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PNEFGJKF_00322	2.54e-266	yacL	-	-	S	-	-	-	domain protein
PNEFGJKF_00323	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PNEFGJKF_00324	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PNEFGJKF_00325	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNEFGJKF_00326	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PNEFGJKF_00327	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PNEFGJKF_00328	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PNEFGJKF_00329	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PNEFGJKF_00330	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PNEFGJKF_00331	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
PNEFGJKF_00333	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
PNEFGJKF_00334	4.1e-273	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PNEFGJKF_00335	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PNEFGJKF_00336	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PNEFGJKF_00337	8.34e-65	-	-	-	-	-	-	-	-
PNEFGJKF_00339	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PNEFGJKF_00340	1.38e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
PNEFGJKF_00341	5.64e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PNEFGJKF_00342	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PNEFGJKF_00343	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PNEFGJKF_00344	1.14e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEFGJKF_00345	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEFGJKF_00346	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PNEFGJKF_00347	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PNEFGJKF_00348	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNEFGJKF_00349	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PNEFGJKF_00350	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PNEFGJKF_00351	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PNEFGJKF_00352	1.11e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PNEFGJKF_00353	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PNEFGJKF_00354	2.72e-237	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PNEFGJKF_00355	6.41e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PNEFGJKF_00356	9.87e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PNEFGJKF_00357	2.92e-183	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PNEFGJKF_00358	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PNEFGJKF_00359	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PNEFGJKF_00360	1.43e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PNEFGJKF_00361	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PNEFGJKF_00362	1.52e-270	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_00363	1.93e-40	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_00364	5.86e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PNEFGJKF_00365	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PNEFGJKF_00366	1.74e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PNEFGJKF_00367	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNEFGJKF_00368	1.62e-293	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PNEFGJKF_00369	2.29e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PNEFGJKF_00370	3.05e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PNEFGJKF_00371	1.37e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNEFGJKF_00372	1.92e-238	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PNEFGJKF_00373	0.0	-	-	-	L	-	-	-	Transposase
PNEFGJKF_00374	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PNEFGJKF_00375	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PNEFGJKF_00377	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PNEFGJKF_00378	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PNEFGJKF_00379	3.5e-112	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PNEFGJKF_00380	0.0	-	-	-	E	-	-	-	amino acid
PNEFGJKF_00381	0.0	ydaO	-	-	E	-	-	-	amino acid
PNEFGJKF_00382	2.63e-53	-	-	-	-	-	-	-	-
PNEFGJKF_00383	3.07e-89	-	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_00384	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_00385	1.4e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PNEFGJKF_00386	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PNEFGJKF_00387	1.4e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PNEFGJKF_00388	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PNEFGJKF_00389	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PNEFGJKF_00390	4.72e-240	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PNEFGJKF_00391	3.65e-67	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
PNEFGJKF_00392	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PNEFGJKF_00393	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PNEFGJKF_00394	4.38e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PNEFGJKF_00395	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PNEFGJKF_00396	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PNEFGJKF_00397	4.49e-178	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PNEFGJKF_00398	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PNEFGJKF_00399	2.37e-216	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PNEFGJKF_00400	2.04e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PNEFGJKF_00401	1.45e-281	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PNEFGJKF_00402	5.33e-211	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
PNEFGJKF_00403	5.98e-116	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PNEFGJKF_00404	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PNEFGJKF_00405	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PNEFGJKF_00406	2.12e-19	-	-	-	-	-	-	-	-
PNEFGJKF_00407	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PNEFGJKF_00408	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PNEFGJKF_00409	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PNEFGJKF_00410	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PNEFGJKF_00411	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PNEFGJKF_00412	6.77e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PNEFGJKF_00414	1.83e-21	-	-	-	-	-	-	-	-
PNEFGJKF_00415	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PNEFGJKF_00416	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PNEFGJKF_00417	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PNEFGJKF_00418	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PNEFGJKF_00419	6.17e-192	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PNEFGJKF_00420	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PNEFGJKF_00421	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PNEFGJKF_00422	9.61e-137	-	-	-	-	-	-	-	-
PNEFGJKF_00423	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PNEFGJKF_00424	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PNEFGJKF_00425	1.2e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PNEFGJKF_00426	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PNEFGJKF_00427	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PNEFGJKF_00428	6.9e-134	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PNEFGJKF_00429	2.36e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PNEFGJKF_00430	2.26e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PNEFGJKF_00431	2.47e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PNEFGJKF_00432	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
PNEFGJKF_00433	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PNEFGJKF_00434	1.99e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
PNEFGJKF_00435	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PNEFGJKF_00436	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PNEFGJKF_00437	5.17e-70	-	-	-	-	-	-	-	-
PNEFGJKF_00438	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PNEFGJKF_00439	7.53e-104	-	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_00440	4.88e-194	-	-	-	S	-	-	-	Cof-like hydrolase
PNEFGJKF_00441	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
PNEFGJKF_00443	2.06e-176	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PNEFGJKF_00444	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PNEFGJKF_00445	7.78e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PNEFGJKF_00446	2.09e-154	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PNEFGJKF_00447	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PNEFGJKF_00448	2.69e-36	-	-	-	-	-	-	-	-
PNEFGJKF_00450	6.11e-44	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
PNEFGJKF_00451	3.87e-111	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00452	2.24e-200	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
PNEFGJKF_00453	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PNEFGJKF_00454	1.37e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
PNEFGJKF_00455	1.92e-209	-	-	-	EG	-	-	-	EamA-like transporter family
PNEFGJKF_00456	1.04e-135	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PNEFGJKF_00457	1.53e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
PNEFGJKF_00458	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
PNEFGJKF_00459	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PNEFGJKF_00460	2.91e-118	-	-	-	-	-	-	-	-
PNEFGJKF_00462	1.28e-75	-	-	-	-	-	-	-	-
PNEFGJKF_00463	6.08e-305	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PNEFGJKF_00467	1.52e-303	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PNEFGJKF_00468	3.92e-87	-	-	-	-	-	-	-	-
PNEFGJKF_00470	1.6e-94	-	-	-	-	-	-	-	-
PNEFGJKF_00472	1.38e-05	-	-	-	-	-	-	-	-
PNEFGJKF_00475	2.49e-180	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNEFGJKF_00476	1.21e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_00477	2.51e-83	-	-	-	-	-	-	-	-
PNEFGJKF_00478	3e-251	ampC	-	-	V	-	-	-	Beta-lactamase
PNEFGJKF_00479	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
PNEFGJKF_00480	3.05e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PNEFGJKF_00481	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PNEFGJKF_00482	1.07e-301	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
PNEFGJKF_00483	1.19e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
PNEFGJKF_00484	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
PNEFGJKF_00485	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PNEFGJKF_00486	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PNEFGJKF_00487	7.63e-217	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PNEFGJKF_00488	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PNEFGJKF_00489	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PNEFGJKF_00490	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PNEFGJKF_00491	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PNEFGJKF_00492	1.27e-250	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PNEFGJKF_00493	4.22e-169	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PNEFGJKF_00494	9.76e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PNEFGJKF_00495	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PNEFGJKF_00496	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNEFGJKF_00497	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PNEFGJKF_00498	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNEFGJKF_00499	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PNEFGJKF_00500	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PNEFGJKF_00501	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PNEFGJKF_00502	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PNEFGJKF_00503	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PNEFGJKF_00504	7.7e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNEFGJKF_00505	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PNEFGJKF_00506	3.77e-56	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PNEFGJKF_00507	7.96e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PNEFGJKF_00508	4.7e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PNEFGJKF_00509	2.98e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PNEFGJKF_00510	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PNEFGJKF_00511	5.42e-276	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PNEFGJKF_00512	6.61e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_00513	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEFGJKF_00514	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
PNEFGJKF_00515	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PNEFGJKF_00516	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PNEFGJKF_00517	2.28e-137	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
PNEFGJKF_00518	3.74e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
PNEFGJKF_00519	1.3e-265	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
PNEFGJKF_00520	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
PNEFGJKF_00521	3.61e-61	-	-	-	-	-	-	-	-
PNEFGJKF_00522	4.83e-312	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PNEFGJKF_00523	3.65e-114	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PNEFGJKF_00524	1.14e-27	-	-	-	-	-	-	-	-
PNEFGJKF_00525	4.92e-99	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
PNEFGJKF_00526	4.16e-180	-	-	-	S	-	-	-	Membrane
PNEFGJKF_00527	1.24e-182	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PNEFGJKF_00528	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PNEFGJKF_00529	6.74e-209	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PNEFGJKF_00530	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00531	2.45e-110	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PNEFGJKF_00532	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_00533	1.14e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PNEFGJKF_00534	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PNEFGJKF_00535	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PNEFGJKF_00536	2.59e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PNEFGJKF_00537	4.1e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PNEFGJKF_00538	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PNEFGJKF_00539	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PNEFGJKF_00540	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PNEFGJKF_00541	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PNEFGJKF_00542	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PNEFGJKF_00543	1.09e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PNEFGJKF_00544	9.51e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PNEFGJKF_00545	3.6e-158	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PNEFGJKF_00546	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PNEFGJKF_00547	7.72e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PNEFGJKF_00548	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PNEFGJKF_00549	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PNEFGJKF_00550	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00551	2.84e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PNEFGJKF_00552	3.68e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PNEFGJKF_00553	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
PNEFGJKF_00554	7.21e-198	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PNEFGJKF_00555	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PNEFGJKF_00556	6.36e-296	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PNEFGJKF_00557	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PNEFGJKF_00558	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PNEFGJKF_00559	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PNEFGJKF_00560	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PNEFGJKF_00561	4.52e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PNEFGJKF_00562	9.97e-245	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PNEFGJKF_00563	1.11e-260	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PNEFGJKF_00564	1.86e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PNEFGJKF_00565	2.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PNEFGJKF_00566	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PNEFGJKF_00567	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PNEFGJKF_00568	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PNEFGJKF_00569	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PNEFGJKF_00570	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PNEFGJKF_00571	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
PNEFGJKF_00572	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PNEFGJKF_00573	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PNEFGJKF_00574	3.01e-126	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PNEFGJKF_00575	3.41e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PNEFGJKF_00576	1.53e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PNEFGJKF_00577	1.16e-124	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PNEFGJKF_00578	1.79e-100	ykuL	-	-	S	-	-	-	(CBS) domain
PNEFGJKF_00579	1.4e-198	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PNEFGJKF_00580	1.6e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PNEFGJKF_00581	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PNEFGJKF_00582	2.93e-58	-	-	-	-	-	-	-	-
PNEFGJKF_00583	6.25e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PNEFGJKF_00584	1.7e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PNEFGJKF_00585	1.03e-181	-	-	-	-	-	-	-	-
PNEFGJKF_00586	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PNEFGJKF_00587	8.77e-237	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PNEFGJKF_00588	2.95e-240	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PNEFGJKF_00589	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PNEFGJKF_00590	3.65e-103	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
PNEFGJKF_00591	3.65e-60	-	-	-	-	-	-	-	-
PNEFGJKF_00592	1.01e-95	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
PNEFGJKF_00594	3.58e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PNEFGJKF_00595	1.36e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PNEFGJKF_00596	6.01e-153	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PNEFGJKF_00597	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PNEFGJKF_00598	1.44e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PNEFGJKF_00599	7.15e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PNEFGJKF_00600	1.29e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PNEFGJKF_00622	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PNEFGJKF_00623	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PNEFGJKF_00624	5.67e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PNEFGJKF_00625	2.15e-267	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PNEFGJKF_00626	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNEFGJKF_00627	2.51e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
PNEFGJKF_00628	9.06e-151	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PNEFGJKF_00629	1.52e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PNEFGJKF_00630	4.28e-225	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNEFGJKF_00633	1.96e-237	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_00634	6.29e-119	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_00635	3.81e-88	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNEFGJKF_00637	6.84e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PNEFGJKF_00638	3.61e-209	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PNEFGJKF_00639	2.64e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PNEFGJKF_00640	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PNEFGJKF_00641	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PNEFGJKF_00642	1.6e-77	-	-	-	-	-	-	-	-
PNEFGJKF_00643	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PNEFGJKF_00644	1.61e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PNEFGJKF_00645	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PNEFGJKF_00646	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PNEFGJKF_00647	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PNEFGJKF_00648	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PNEFGJKF_00649	2.16e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PNEFGJKF_00650	7.77e-198	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PNEFGJKF_00651	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PNEFGJKF_00652	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PNEFGJKF_00653	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PNEFGJKF_00654	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PNEFGJKF_00655	1.84e-190	ylmH	-	-	S	-	-	-	S4 domain protein
PNEFGJKF_00656	6.11e-108	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PNEFGJKF_00657	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PNEFGJKF_00658	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PNEFGJKF_00659	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PNEFGJKF_00660	1.54e-33	-	-	-	-	-	-	-	-
PNEFGJKF_00661	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PNEFGJKF_00662	1.63e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PNEFGJKF_00663	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PNEFGJKF_00664	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PNEFGJKF_00665	4.89e-160	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PNEFGJKF_00666	1.1e-156	-	-	-	S	-	-	-	repeat protein
PNEFGJKF_00667	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PNEFGJKF_00668	3.64e-224	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PNEFGJKF_00669	6.48e-243	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PNEFGJKF_00670	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PNEFGJKF_00671	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PNEFGJKF_00672	1.2e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PNEFGJKF_00673	4.19e-286	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PNEFGJKF_00674	5.62e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PNEFGJKF_00675	1.62e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PNEFGJKF_00676	3.19e-283	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNEFGJKF_00677	1.56e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PNEFGJKF_00678	6.43e-05	cdaR_3	-	-	QT	ko:K02647	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
PNEFGJKF_00679	6.84e-35	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
PNEFGJKF_00680	2.31e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
PNEFGJKF_00681	1.73e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PNEFGJKF_00682	5.28e-76	-	-	-	-	-	-	-	-
PNEFGJKF_00684	5.28e-254	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PNEFGJKF_00685	4.37e-39	-	-	-	-	-	-	-	-
PNEFGJKF_00686	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
PNEFGJKF_00687	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PNEFGJKF_00688	2.79e-107	-	-	-	-	-	-	-	-
PNEFGJKF_00689	8.3e-134	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PNEFGJKF_00690	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PNEFGJKF_00691	2.31e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PNEFGJKF_00692	1.34e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PNEFGJKF_00693	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PNEFGJKF_00694	2.87e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PNEFGJKF_00695	2.12e-178	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PNEFGJKF_00696	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PNEFGJKF_00697	2.75e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PNEFGJKF_00698	3.83e-61	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PNEFGJKF_00699	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PNEFGJKF_00700	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PNEFGJKF_00701	1.56e-254	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PNEFGJKF_00702	8.7e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PNEFGJKF_00703	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PNEFGJKF_00704	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PNEFGJKF_00705	5.84e-203	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PNEFGJKF_00706	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PNEFGJKF_00707	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PNEFGJKF_00708	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNEFGJKF_00709	1.3e-210	-	-	-	S	-	-	-	Tetratricopeptide repeat
PNEFGJKF_00710	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PNEFGJKF_00711	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PNEFGJKF_00712	5.06e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PNEFGJKF_00713	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PNEFGJKF_00714	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PNEFGJKF_00715	2.44e-20	-	-	-	-	-	-	-	-
PNEFGJKF_00716	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PNEFGJKF_00717	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PNEFGJKF_00718	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PNEFGJKF_00719	1.05e-201	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEFGJKF_00720	5.25e-106	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PNEFGJKF_00724	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
PNEFGJKF_00727	3.72e-111	-	-	-	L	-	-	-	HNH nucleases
PNEFGJKF_00729	1.34e-103	terS	-	-	L	-	-	-	Phage terminase, small subunit
PNEFGJKF_00730	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PNEFGJKF_00732	9.18e-265	-	-	-	S	-	-	-	Phage portal protein
PNEFGJKF_00733	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
PNEFGJKF_00734	3.04e-100	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
PNEFGJKF_00735	6.69e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNEFGJKF_00737	3.18e-167	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNEFGJKF_00738	1.49e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PNEFGJKF_00739	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PNEFGJKF_00740	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
PNEFGJKF_00741	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PNEFGJKF_00742	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PNEFGJKF_00743	2.92e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PNEFGJKF_00744	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PNEFGJKF_00745	8.74e-235	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEFGJKF_00746	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PNEFGJKF_00747	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PNEFGJKF_00748	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PNEFGJKF_00749	7.32e-124	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PNEFGJKF_00750	5.49e-282	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_00751	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00752	6.92e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PNEFGJKF_00753	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PNEFGJKF_00754	9.87e-300	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PNEFGJKF_00755	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PNEFGJKF_00756	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNEFGJKF_00757	7.73e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PNEFGJKF_00758	3.54e-276	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PNEFGJKF_00759	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PNEFGJKF_00760	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
PNEFGJKF_00761	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PNEFGJKF_00762	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PNEFGJKF_00763	1.48e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PNEFGJKF_00764	4.14e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PNEFGJKF_00765	3.09e-85	-	-	-	-	-	-	-	-
PNEFGJKF_00766	1.37e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PNEFGJKF_00767	2.83e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PNEFGJKF_00768	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PNEFGJKF_00769	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PNEFGJKF_00770	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PNEFGJKF_00771	4.55e-288	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_00772	1.7e-182	-	-	-	-	-	-	-	-
PNEFGJKF_00773	4.29e-18	-	-	-	-	-	-	-	-
PNEFGJKF_00774	2.44e-99	-	-	-	-	-	-	-	-
PNEFGJKF_00775	5.09e-107	-	-	-	-	-	-	-	-
PNEFGJKF_00776	2.6e-14	-	-	-	K	-	-	-	Peptidase S24-like
PNEFGJKF_00777	1.21e-30	-	-	-	K	-	-	-	Peptidase S24-like
PNEFGJKF_00778	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNEFGJKF_00779	3.16e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
PNEFGJKF_00780	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PNEFGJKF_00782	3.36e-77	-	-	-	-	-	-	-	-
PNEFGJKF_00783	2.15e-234	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PNEFGJKF_00784	1.05e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PNEFGJKF_00785	2.38e-72	-	-	-	-	-	-	-	-
PNEFGJKF_00786	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PNEFGJKF_00787	5.38e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PNEFGJKF_00788	2.03e-218	-	-	-	G	-	-	-	Phosphotransferase enzyme family
PNEFGJKF_00789	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PNEFGJKF_00790	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_00791	1.01e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00792	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PNEFGJKF_00793	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PNEFGJKF_00794	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PNEFGJKF_00795	6.44e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PNEFGJKF_00796	6.2e-305	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PNEFGJKF_00797	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PNEFGJKF_00798	7.55e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PNEFGJKF_00799	4.86e-233	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PNEFGJKF_00800	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PNEFGJKF_00801	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PNEFGJKF_00802	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PNEFGJKF_00803	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PNEFGJKF_00804	3.71e-190	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PNEFGJKF_00805	6.69e-238	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PNEFGJKF_00806	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PNEFGJKF_00807	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PNEFGJKF_00808	2.54e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PNEFGJKF_00809	2.51e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNEFGJKF_00810	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PNEFGJKF_00811	1.23e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PNEFGJKF_00812	1.93e-203	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PNEFGJKF_00813	1.72e-305	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PNEFGJKF_00814	5.59e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PNEFGJKF_00815	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PNEFGJKF_00816	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PNEFGJKF_00817	9.26e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PNEFGJKF_00818	4.23e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PNEFGJKF_00819	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEFGJKF_00820	1.05e-181	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PNEFGJKF_00821	1.15e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PNEFGJKF_00822	2.58e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PNEFGJKF_00823	3.23e-134	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PNEFGJKF_00824	8.62e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
PNEFGJKF_00825	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PNEFGJKF_00826	1.81e-70	-	-	-	M	-	-	-	Lysin motif
PNEFGJKF_00827	4.62e-154	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PNEFGJKF_00828	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PNEFGJKF_00829	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PNEFGJKF_00830	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PNEFGJKF_00831	1.64e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PNEFGJKF_00832	1.8e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PNEFGJKF_00833	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_00834	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PNEFGJKF_00835	4.1e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PNEFGJKF_00836	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PNEFGJKF_00837	9.45e-198	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PNEFGJKF_00838	1.18e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PNEFGJKF_00839	2.01e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PNEFGJKF_00840	4.62e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PNEFGJKF_00841	2.53e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PNEFGJKF_00842	3.16e-184	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNEFGJKF_00843	2.44e-210	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PNEFGJKF_00844	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PNEFGJKF_00845	2.19e-218	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PNEFGJKF_00846	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PNEFGJKF_00847	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNEFGJKF_00848	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNEFGJKF_00849	3.56e-113	-	-	-	F	-	-	-	NUDIX domain
PNEFGJKF_00850	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PNEFGJKF_00851	3.33e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_00852	2.59e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PNEFGJKF_00853	4.18e-43	-	-	-	-	-	-	-	-
PNEFGJKF_00855	9.65e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PNEFGJKF_00856	1.15e-82	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PNEFGJKF_00857	3.09e-35	-	-	-	-	-	-	-	-
PNEFGJKF_00858	1.38e-125	-	-	-	-	-	-	-	-
PNEFGJKF_00859	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PNEFGJKF_00860	2.49e-235	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
PNEFGJKF_00861	8.68e-257	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PNEFGJKF_00862	7.28e-305	int	-	-	L	ko:K06400	-	ko00000	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PNEFGJKF_00863	4.28e-192	-	-	-	-	-	-	-	-
PNEFGJKF_00865	3.75e-98	-	-	-	-	-	-	-	-
PNEFGJKF_00866	2.86e-93	-	-	-	S	-	-	-	IrrE N-terminal-like domain
PNEFGJKF_00867	7.08e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
PNEFGJKF_00868	3.73e-44	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_00869	1.1e-180	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
PNEFGJKF_00872	1.98e-44	-	-	-	-	-	-	-	-
PNEFGJKF_00873	1.35e-05	-	-	-	K	-	-	-	XRE family transcriptional regulator
PNEFGJKF_00877	1.03e-211	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PNEFGJKF_00878	2.65e-210	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
PNEFGJKF_00879	1.65e-205	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PNEFGJKF_00880	2.3e-78	-	-	-	-	-	-	-	-
PNEFGJKF_00889	2.17e-10	-	-	-	-	-	-	-	-
PNEFGJKF_00892	4.49e-102	-	-	-	-	-	-	-	-
PNEFGJKF_00894	8.42e-163	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
PNEFGJKF_00895	7.15e-95	-	-	-	-	-	-	-	-
PNEFGJKF_00896	1.14e-183	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
PNEFGJKF_00898	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
PNEFGJKF_00899	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PNEFGJKF_00900	5.45e-231	-	-	-	S	-	-	-	Phage Mu protein F like protein
PNEFGJKF_00902	1e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
PNEFGJKF_00903	8.1e-261	gpG	-	-	-	-	-	-	-
PNEFGJKF_00904	1.8e-83	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNEFGJKF_00905	3.92e-70	-	-	-	-	-	-	-	-
PNEFGJKF_00906	5.18e-128	-	-	-	-	-	-	-	-
PNEFGJKF_00907	5.74e-94	-	-	-	-	-	-	-	-
PNEFGJKF_00908	2.24e-159	-	-	-	-	-	-	-	-
PNEFGJKF_00909	1.55e-122	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
PNEFGJKF_00910	0.0	-	-	-	D	-	-	-	domain protein
PNEFGJKF_00911	1.49e-222	-	-	-	S	-	-	-	Phage tail protein
PNEFGJKF_00912	0.0	-	-	-	S	-	-	-	Peptidase family M23
PNEFGJKF_00913	8.21e-19	-	-	-	LM	-	-	-	gp58-like protein
PNEFGJKF_00917	6.49e-268	-	-	-	-	-	-	-	-
PNEFGJKF_00920	2.78e-100	-	-	-	-	-	-	-	-
PNEFGJKF_00922	2.35e-106	-	-	-	S	-	-	-	Bacteriophage holin family
PNEFGJKF_00923	1.5e-247	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
PNEFGJKF_00924	8.65e-20	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PNEFGJKF_00925	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PNEFGJKF_00926	2.06e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PNEFGJKF_00927	1.81e-41	-	-	-	-	-	-	-	-
PNEFGJKF_00928	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PNEFGJKF_00929	1.26e-60	-	-	-	-	-	-	-	-
PNEFGJKF_00930	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PNEFGJKF_00931	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PNEFGJKF_00932	6.46e-131	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PNEFGJKF_00933	4.33e-146	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PNEFGJKF_00934	3.55e-231	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_00935	6.57e-239	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PNEFGJKF_00936	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PNEFGJKF_00937	1.5e-48	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
PNEFGJKF_00938	0.0	-	-	-	L	-	-	-	PLD-like domain
PNEFGJKF_00940	3.42e-233	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
PNEFGJKF_00941	1.19e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PNEFGJKF_00942	3.2e-138	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PNEFGJKF_00943	1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PNEFGJKF_00944	2.33e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PNEFGJKF_00945	1.81e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
PNEFGJKF_00946	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PNEFGJKF_00947	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
PNEFGJKF_00948	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
PNEFGJKF_00949	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
PNEFGJKF_00950	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PNEFGJKF_00951	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PNEFGJKF_00952	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PNEFGJKF_00953	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
PNEFGJKF_00954	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PNEFGJKF_00955	2.11e-308	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PNEFGJKF_00956	2.43e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PNEFGJKF_00957	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PNEFGJKF_00958	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PNEFGJKF_00959	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PNEFGJKF_00960	2e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PNEFGJKF_00961	6.38e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
PNEFGJKF_00962	7.08e-52	-	-	-	S	-	-	-	Cytochrome B5
PNEFGJKF_00963	4.21e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PNEFGJKF_00964	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PNEFGJKF_00965	3.63e-190	-	-	-	O	-	-	-	Band 7 protein
PNEFGJKF_00966	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
PNEFGJKF_00967	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
PNEFGJKF_00968	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
PNEFGJKF_00969	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
PNEFGJKF_00970	1.19e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PNEFGJKF_00971	1.7e-101	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PNEFGJKF_00972	4.28e-102	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PNEFGJKF_00973	1.12e-246	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
PNEFGJKF_00974	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PNEFGJKF_00975	8.22e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PNEFGJKF_00976	2.27e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PNEFGJKF_00977	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PNEFGJKF_00978	1.74e-226	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PNEFGJKF_00979	1.09e-221	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PNEFGJKF_00980	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PNEFGJKF_00981	1.15e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PNEFGJKF_00982	2.48e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PNEFGJKF_00983	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
PNEFGJKF_00984	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PNEFGJKF_00985	1.21e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PNEFGJKF_00986	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PNEFGJKF_00987	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PNEFGJKF_00988	6.11e-111	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PNEFGJKF_00989	6.84e-296	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PNEFGJKF_00990	7.66e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PNEFGJKF_00991	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
PNEFGJKF_00992	8.85e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PNEFGJKF_00993	7.11e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNEFGJKF_00994	1.93e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
PNEFGJKF_00995	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PNEFGJKF_00996	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PNEFGJKF_00997	5.11e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
PNEFGJKF_00998	7.18e-126	-	-	-	-	-	-	-	-
PNEFGJKF_00999	1.29e-155	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PNEFGJKF_01000	9.18e-206	gspA	-	-	M	-	-	-	family 8
PNEFGJKF_01001	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
PNEFGJKF_01002	1.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PNEFGJKF_01003	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01004	9.81e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PNEFGJKF_01005	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PNEFGJKF_01006	2.79e-225	yvgN	-	-	C	-	-	-	Aldo keto reductase
PNEFGJKF_01007	2.08e-208	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
PNEFGJKF_01008	7.72e-114	-	-	-	C	-	-	-	Flavodoxin
PNEFGJKF_01009	1.42e-82	-	-	-	S	-	-	-	Cupin domain
PNEFGJKF_01010	1.35e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
PNEFGJKF_01011	2.6e-312	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PNEFGJKF_01012	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PNEFGJKF_01013	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PNEFGJKF_01014	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
PNEFGJKF_01015	2.92e-192	-	-	-	S	-	-	-	DUF218 domain
PNEFGJKF_01016	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEFGJKF_01017	7.82e-80	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNEFGJKF_01018	1.27e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNEFGJKF_01019	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PNEFGJKF_01020	2.9e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
PNEFGJKF_01021	3.41e-296	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PNEFGJKF_01022	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PNEFGJKF_01024	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PNEFGJKF_01025	1.78e-204	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PNEFGJKF_01026	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNEFGJKF_01027	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01028	7.11e-57	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
PNEFGJKF_01029	5.07e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PNEFGJKF_01030	2.7e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PNEFGJKF_01031	3.57e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
PNEFGJKF_01032	5.57e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PNEFGJKF_01033	5.02e-29	-	-	-	-	-	-	-	-
PNEFGJKF_01034	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PNEFGJKF_01035	3.73e-203	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PNEFGJKF_01036	1.94e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PNEFGJKF_01038	3.01e-63	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_01039	6.4e-26	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
PNEFGJKF_01040	1.54e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_01041	3.7e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_01042	9.5e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01043	5.51e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PNEFGJKF_01044	5.47e-151	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PNEFGJKF_01045	1.57e-73	-	-	-	-	-	-	-	-
PNEFGJKF_01054	1.04e-172	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PNEFGJKF_01055	5.87e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PNEFGJKF_01056	7.2e-185	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PNEFGJKF_01057	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PNEFGJKF_01058	1.38e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PNEFGJKF_01059	1.3e-99	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PNEFGJKF_01060	1.27e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNEFGJKF_01061	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PNEFGJKF_01062	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PNEFGJKF_01063	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PNEFGJKF_01064	4.83e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PNEFGJKF_01065	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PNEFGJKF_01066	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PNEFGJKF_01068	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_01069	9.94e-148	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_01070	6.64e-161	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	transposase activity
PNEFGJKF_01071	8.81e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
PNEFGJKF_01072	1.15e-152	-	-	-	L	-	-	-	Integrase
PNEFGJKF_01073	3.97e-198	-	-	-	EG	-	-	-	EamA-like transporter family
PNEFGJKF_01074	0.0	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01075	6.19e-163	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_01076	3.84e-60	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
PNEFGJKF_01077	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01078	2.4e-231	-	-	-	-	-	-	-	-
PNEFGJKF_01079	7.69e-100	-	-	-	-	-	-	-	-
PNEFGJKF_01080	5.16e-115	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PNEFGJKF_01082	1.01e-69	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNEFGJKF_01083	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_01084	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
PNEFGJKF_01085	6.11e-68	-	-	-	-	-	-	-	-
PNEFGJKF_01086	2.03e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PNEFGJKF_01087	3e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PNEFGJKF_01088	8.1e-153	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PNEFGJKF_01089	6.12e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
PNEFGJKF_01090	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PNEFGJKF_01091	5.8e-149	-	-	-	I	-	-	-	Acid phosphatase homologues
PNEFGJKF_01093	1.5e-85	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PNEFGJKF_01094	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PNEFGJKF_01096	9.88e-239	-	-	-	-	-	-	-	-
PNEFGJKF_01097	7.82e-37	-	-	-	-	-	-	-	-
PNEFGJKF_01098	7.77e-196	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PNEFGJKF_01099	1.9e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PNEFGJKF_01100	3.82e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PNEFGJKF_01101	5.2e-89	-	-	-	-	-	-	-	-
PNEFGJKF_01102	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PNEFGJKF_01103	1.24e-136	-	-	-	L	-	-	-	nuclease
PNEFGJKF_01104	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PNEFGJKF_01105	7.33e-271	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PNEFGJKF_01106	1.63e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PNEFGJKF_01107	1.77e-203	snf	-	-	KL	-	-	-	domain protein
PNEFGJKF_01108	0.0	snf	-	-	KL	-	-	-	domain protein
PNEFGJKF_01110	4.51e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
PNEFGJKF_01111	3.07e-05	-	-	-	K	-	-	-	sequence-specific DNA binding
PNEFGJKF_01113	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PNEFGJKF_01114	1.49e-225	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PNEFGJKF_01115	9.76e-93	-	-	-	O	-	-	-	Preprotein translocase subunit SecB
PNEFGJKF_01116	3.33e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_01117	1.01e-203	-	-	-	-	-	-	-	-
PNEFGJKF_01118	7.45e-181	-	-	-	L	-	-	-	Bacterial dnaA protein
PNEFGJKF_01119	2.9e-295	-	-	-	L	-	-	-	Integrase core domain
PNEFGJKF_01120	1.93e-266	-	-	-	L	-	-	-	DNA helicase
PNEFGJKF_01121	0.0	-	-	-	S	ko:K07459	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PNEFGJKF_01122	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
PNEFGJKF_01123	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
PNEFGJKF_01124	8.85e-208	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PNEFGJKF_01125	1.55e-224	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PNEFGJKF_01126	1.31e-28	epsB	-	-	M	-	-	-	biosynthesis protein
PNEFGJKF_01127	2.91e-230	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PNEFGJKF_01128	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNEFGJKF_01129	2.24e-123	-	-	-	-	-	-	-	-
PNEFGJKF_01130	4.69e-236	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_01131	1.68e-43	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_01132	2e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01133	7.59e-37	-	-	-	-	-	-	-	-
PNEFGJKF_01134	6.28e-136	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PNEFGJKF_01135	4.1e-51	-	-	-	-	-	-	-	-
PNEFGJKF_01136	8.53e-120	-	-	-	-	-	-	-	-
PNEFGJKF_01137	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PNEFGJKF_01138	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PNEFGJKF_01139	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PNEFGJKF_01140	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNEFGJKF_01141	1.61e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01142	3.09e-209	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNEFGJKF_01143	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
PNEFGJKF_01144	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
PNEFGJKF_01145	8.64e-196	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PNEFGJKF_01146	8.1e-160	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PNEFGJKF_01149	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNEFGJKF_01150	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PNEFGJKF_01151	6.3e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PNEFGJKF_01152	2.22e-168	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PNEFGJKF_01153	7.22e-286	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PNEFGJKF_01154	4.7e-186	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
PNEFGJKF_01155	8.07e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PNEFGJKF_01156	8.36e-231	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PNEFGJKF_01157	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PNEFGJKF_01158	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PNEFGJKF_01159	5.12e-243	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PNEFGJKF_01160	2.68e-110	-	-	-	-	-	-	-	-
PNEFGJKF_01161	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01162	1.31e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PNEFGJKF_01163	5.41e-73	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
PNEFGJKF_01164	4.45e-47	-	-	-	-	-	-	-	-
PNEFGJKF_01165	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01166	6.1e-247	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
PNEFGJKF_01167	6.74e-80	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
PNEFGJKF_01168	4.85e-57	-	-	-	-	-	-	-	-
PNEFGJKF_01170	9.71e-101	-	-	-	-	-	-	-	-
PNEFGJKF_01173	6.49e-268	-	-	-	-	-	-	-	-
PNEFGJKF_01177	2.9e-23	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
PNEFGJKF_01178	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
PNEFGJKF_01179	7.27e-207	-	-	-	S	-	-	-	Phage tail protein
PNEFGJKF_01180	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PNEFGJKF_01181	6.12e-83	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
PNEFGJKF_01182	4.5e-174	-	-	-	S	-	-	-	Phage tail tube protein
PNEFGJKF_01183	3.7e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
PNEFGJKF_01184	1.11e-92	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PNEFGJKF_01185	4.51e-77	-	-	-	S	-	-	-	Phage head-tail joining protein
PNEFGJKF_01186	4.41e-80	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PNEFGJKF_01187	3.68e-276	-	-	-	S	-	-	-	Phage capsid family
PNEFGJKF_01188	9.31e-166	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PNEFGJKF_01189	1.85e-283	-	-	-	S	-	-	-	Phage portal protein
PNEFGJKF_01190	0.0	-	-	-	S	-	-	-	Phage Terminase
PNEFGJKF_01191	1.59e-13	-	-	-	-	-	-	-	-
PNEFGJKF_01193	1.1e-108	-	-	-	L	-	-	-	Phage terminase, small subunit
PNEFGJKF_01194	1.51e-132	-	-	-	L	-	-	-	HNH nucleases
PNEFGJKF_01195	2.71e-14	-	-	-	-	-	-	-	-
PNEFGJKF_01196	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01198	9.86e-200	-	-	-	-	-	-	-	-
PNEFGJKF_01199	4.49e-102	-	-	-	-	-	-	-	-
PNEFGJKF_01202	2.17e-10	-	-	-	-	-	-	-	-
PNEFGJKF_01211	2.3e-78	-	-	-	-	-	-	-	-
PNEFGJKF_01212	1.65e-205	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PNEFGJKF_01213	5.75e-196	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
PNEFGJKF_01214	2.9e-228	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PNEFGJKF_01218	3.7e-25	-	-	-	-	-	-	-	-
PNEFGJKF_01219	2.73e-181	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
PNEFGJKF_01220	2.72e-42	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_01221	2.37e-95	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PNEFGJKF_01222	2.76e-108	-	-	-	E	-	-	-	IrrE N-terminal-like domain
PNEFGJKF_01223	1.48e-66	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
PNEFGJKF_01224	2.86e-68	-	-	-	-	-	-	-	-
PNEFGJKF_01225	1.66e-269	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_01226	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PNEFGJKF_01227	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
PNEFGJKF_01228	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PNEFGJKF_01229	1.86e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PNEFGJKF_01230	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PNEFGJKF_01231	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PNEFGJKF_01232	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PNEFGJKF_01233	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PNEFGJKF_01234	4.22e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PNEFGJKF_01235	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PNEFGJKF_01236	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PNEFGJKF_01237	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PNEFGJKF_01238	1.41e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PNEFGJKF_01239	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PNEFGJKF_01240	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PNEFGJKF_01241	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PNEFGJKF_01242	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PNEFGJKF_01243	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PNEFGJKF_01244	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PNEFGJKF_01245	1.59e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PNEFGJKF_01246	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PNEFGJKF_01247	4.45e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PNEFGJKF_01248	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PNEFGJKF_01249	1.81e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PNEFGJKF_01250	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PNEFGJKF_01251	1.97e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PNEFGJKF_01252	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PNEFGJKF_01253	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PNEFGJKF_01254	9e-72	-	-	-	-	-	-	-	-
PNEFGJKF_01255	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PNEFGJKF_01256	6.71e-102	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PNEFGJKF_01257	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PNEFGJKF_01258	3.59e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PNEFGJKF_01259	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PNEFGJKF_01260	5.04e-283	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PNEFGJKF_01261	2.71e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PNEFGJKF_01262	9.11e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PNEFGJKF_01263	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PNEFGJKF_01264	6.38e-159	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
PNEFGJKF_01265	2.83e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PNEFGJKF_01266	1.63e-171	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PNEFGJKF_01267	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PNEFGJKF_01268	8.76e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PNEFGJKF_01269	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PNEFGJKF_01270	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_01273	3.61e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
PNEFGJKF_01274	2.07e-239	-	-	-	-	-	-	-	-
PNEFGJKF_01275	8.42e-204	-	-	-	-	-	-	-	-
PNEFGJKF_01276	7.62e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PNEFGJKF_01277	6.94e-132	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PNEFGJKF_01278	1.51e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PNEFGJKF_01279	1.28e-18	-	-	-	-	-	-	-	-
PNEFGJKF_01280	1.31e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PNEFGJKF_01281	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PNEFGJKF_01282	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PNEFGJKF_01283	1.06e-228	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PNEFGJKF_01284	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PNEFGJKF_01285	2.67e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PNEFGJKF_01286	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PNEFGJKF_01287	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PNEFGJKF_01288	1.44e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PNEFGJKF_01289	9.73e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PNEFGJKF_01290	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PNEFGJKF_01291	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PNEFGJKF_01292	0.0	-	-	-	S	-	-	-	membrane
PNEFGJKF_01293	4.64e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PNEFGJKF_01294	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PNEFGJKF_01295	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PNEFGJKF_01296	6.17e-151	-	-	-	M	-	-	-	PFAM NLP P60 protein
PNEFGJKF_01297	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNEFGJKF_01298	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PNEFGJKF_01299	4.77e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNEFGJKF_01300	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PNEFGJKF_01301	6.64e-187	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNEFGJKF_01302	1.07e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PNEFGJKF_01303	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNEFGJKF_01304	5.74e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PNEFGJKF_01305	1.84e-298	-	-	-	V	-	-	-	MatE
PNEFGJKF_01306	0.0	potE	-	-	E	-	-	-	Amino Acid
PNEFGJKF_01307	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PNEFGJKF_01308	1.38e-155	csrR	-	-	K	-	-	-	response regulator
PNEFGJKF_01309	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PNEFGJKF_01310	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PNEFGJKF_01311	1.75e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PNEFGJKF_01312	9.84e-183	yqeM	-	-	Q	-	-	-	Methyltransferase
PNEFGJKF_01313	2.3e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PNEFGJKF_01314	1.07e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PNEFGJKF_01315	4.36e-161	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PNEFGJKF_01316	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PNEFGJKF_01317	1.9e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PNEFGJKF_01318	1.91e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PNEFGJKF_01319	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PNEFGJKF_01320	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PNEFGJKF_01321	2.15e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PNEFGJKF_01322	2.57e-223	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PNEFGJKF_01323	2.42e-300	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PNEFGJKF_01324	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PNEFGJKF_01325	5.5e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PNEFGJKF_01326	8.18e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PNEFGJKF_01327	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PNEFGJKF_01328	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PNEFGJKF_01329	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PNEFGJKF_01330	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PNEFGJKF_01331	3.43e-154	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNEFGJKF_01332	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
PNEFGJKF_01333	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
PNEFGJKF_01334	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PNEFGJKF_01335	5.08e-237	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PNEFGJKF_01336	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PNEFGJKF_01337	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01338	0.0	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
PNEFGJKF_01339	1.24e-233	-	-	-	S	-	-	-	YSIRK type signal peptide
PNEFGJKF_01340	4.53e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PNEFGJKF_01341	2.95e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PNEFGJKF_01342	1.39e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01343	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PNEFGJKF_01345	3.01e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PNEFGJKF_01346	0.0	yhaN	-	-	L	-	-	-	AAA domain
PNEFGJKF_01347	4.1e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PNEFGJKF_01348	3.9e-79	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PNEFGJKF_01349	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PNEFGJKF_01350	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PNEFGJKF_01351	1.51e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PNEFGJKF_01352	4.93e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PNEFGJKF_01354	1.49e-54	-	-	-	-	-	-	-	-
PNEFGJKF_01355	4.61e-61	-	-	-	-	-	-	-	-
PNEFGJKF_01356	5.66e-278	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
PNEFGJKF_01357	8.88e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
PNEFGJKF_01358	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PNEFGJKF_01359	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
PNEFGJKF_01360	4.05e-124	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PNEFGJKF_01361	1.22e-74	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PNEFGJKF_01362	5.82e-96	-	-	-	-	-	-	-	-
PNEFGJKF_01364	9.17e-59	-	-	-	-	-	-	-	-
PNEFGJKF_01365	2.21e-155	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNEFGJKF_01366	1.52e-43	-	-	-	-	-	-	-	-
PNEFGJKF_01367	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PNEFGJKF_01368	2.63e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PNEFGJKF_01369	5.33e-147	-	-	-	-	-	-	-	-
PNEFGJKF_01370	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PNEFGJKF_01371	9.46e-242	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PNEFGJKF_01372	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PNEFGJKF_01373	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PNEFGJKF_01374	9.07e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PNEFGJKF_01375	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PNEFGJKF_01376	8.74e-57	-	-	-	-	-	-	-	-
PNEFGJKF_01377	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PNEFGJKF_01378	9.47e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PNEFGJKF_01379	4.49e-130	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PNEFGJKF_01380	7.96e-41	-	-	-	-	-	-	-	-
PNEFGJKF_01381	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01382	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PNEFGJKF_01383	8.53e-304	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PNEFGJKF_01384	2.01e-134	-	-	-	V	-	-	-	VanZ like family
PNEFGJKF_01385	7.03e-33	-	-	-	-	-	-	-	-
PNEFGJKF_01386	2.05e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PNEFGJKF_01387	7.91e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PNEFGJKF_01388	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
PNEFGJKF_01389	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PNEFGJKF_01390	2.42e-201	yeaE	-	-	S	-	-	-	Aldo keto
PNEFGJKF_01391	2.29e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
PNEFGJKF_01392	4.87e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PNEFGJKF_01393	4.36e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PNEFGJKF_01394	2.13e-142	-	-	-	M	-	-	-	LysM domain protein
PNEFGJKF_01395	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
PNEFGJKF_01396	1.32e-131	-	-	-	M	-	-	-	LysM domain protein
PNEFGJKF_01397	7.9e-214	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
PNEFGJKF_01398	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PNEFGJKF_01399	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PNEFGJKF_01400	9.83e-316	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PNEFGJKF_01401	9.73e-132	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PNEFGJKF_01413	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PNEFGJKF_01414	8e-230	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PNEFGJKF_01415	4.82e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PNEFGJKF_01416	6.85e-295	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PNEFGJKF_01417	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PNEFGJKF_01418	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PNEFGJKF_01419	9.69e-38	-	-	-	-	-	-	-	-
PNEFGJKF_01420	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PNEFGJKF_01421	1.56e-130	-	-	-	S	-	-	-	Pfam:DUF3816
PNEFGJKF_01422	9.48e-183	-	-	-	G	-	-	-	MucBP domain
PNEFGJKF_01423	1.27e-151	-	-	-	-	-	-	-	-
PNEFGJKF_01424	4.04e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01425	1.45e-85	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
PNEFGJKF_01426	6.81e-221	-	3.2.1.23, 3.2.1.89	-	G	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	arabinogalactan endo-1,4-beta-galactosidase activity
PNEFGJKF_01427	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
PNEFGJKF_01428	8.12e-64	-	-	-	S	-	-	-	dextransucrase activity
PNEFGJKF_01429	1.45e-57	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_01430	1.08e-209	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNEFGJKF_01431	2.05e-72	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01432	2.09e-41	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01433	2.33e-316	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01434	1.21e-35	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01435	9.89e-76	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_01436	5.96e-125	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
PNEFGJKF_01437	7.81e-148	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
PNEFGJKF_01439	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
PNEFGJKF_01440	7.45e-07	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
PNEFGJKF_01441	7.03e-156	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PNEFGJKF_01442	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01443	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01444	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PNEFGJKF_01445	7.37e-300	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PNEFGJKF_01446	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PNEFGJKF_01447	5.17e-252	yueF	-	-	S	-	-	-	AI-2E family transporter
PNEFGJKF_01448	1.11e-190	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
PNEFGJKF_01449	4.77e-289	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PNEFGJKF_01450	2.43e-156	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_01451	1.21e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01452	3.07e-102	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNEFGJKF_01453	1.23e-171	-	-	-	O	-	-	-	Bacterial dnaA protein
PNEFGJKF_01454	6.69e-304	-	-	-	L	-	-	-	Integrase core domain
PNEFGJKF_01455	4.14e-230	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PNEFGJKF_01456	3.2e-68	-	-	-	-	-	-	-	-
PNEFGJKF_01457	1.51e-204	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
PNEFGJKF_01458	1.48e-242	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
PNEFGJKF_01459	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01460	8.56e-236	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
PNEFGJKF_01461	2.11e-250	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
PNEFGJKF_01462	3.11e-248	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PNEFGJKF_01463	1.23e-255	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
PNEFGJKF_01464	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PNEFGJKF_01465	1.82e-137	-	-	-	M	-	-	-	biosynthesis protein
PNEFGJKF_01466	2.22e-276	cps3F	-	-	-	-	-	-	-
PNEFGJKF_01467	3.84e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PNEFGJKF_01468	3.06e-157	-	-	-	M	-	-	-	Bacterial sugar transferase
PNEFGJKF_01469	5.87e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PNEFGJKF_01470	2.95e-193	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PNEFGJKF_01471	6.84e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PNEFGJKF_01472	6.21e-43	-	-	-	-	-	-	-	-
PNEFGJKF_01473	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PNEFGJKF_01474	9.09e-204	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PNEFGJKF_01475	0.0	potE	-	-	E	-	-	-	Amino Acid
PNEFGJKF_01476	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PNEFGJKF_01477	5.05e-283	arcT	-	-	E	-	-	-	Aminotransferase
PNEFGJKF_01478	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PNEFGJKF_01479	1.64e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PNEFGJKF_01480	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
PNEFGJKF_01481	4.07e-72	-	-	-	-	-	-	-	-
PNEFGJKF_01482	6.52e-270	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PNEFGJKF_01484	3.45e-300	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PNEFGJKF_01485	1.31e-245	mocA	-	-	S	-	-	-	Oxidoreductase
PNEFGJKF_01486	7.97e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PNEFGJKF_01487	1.66e-142	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PNEFGJKF_01488	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PNEFGJKF_01489	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PNEFGJKF_01490	1.32e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
PNEFGJKF_01491	3.32e-107	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
PNEFGJKF_01492	1.59e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PNEFGJKF_01493	7.31e-27	-	-	-	-	-	-	-	-
PNEFGJKF_01494	2.44e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PNEFGJKF_01495	2.57e-103	-	-	-	K	-	-	-	LytTr DNA-binding domain
PNEFGJKF_01496	4.56e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PNEFGJKF_01497	1.22e-218	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PNEFGJKF_01498	4.43e-100	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PNEFGJKF_01499	1.04e-168	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_01500	1.85e-109	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PNEFGJKF_01501	3.87e-161	pnb	-	-	C	-	-	-	nitroreductase
PNEFGJKF_01502	5.22e-120	-	-	-	-	-	-	-	-
PNEFGJKF_01503	2.89e-110	yvbK	-	-	K	-	-	-	GNAT family
PNEFGJKF_01504	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
PNEFGJKF_01505	8.89e-269	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PNEFGJKF_01506	2.27e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PNEFGJKF_01507	3.01e-92	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PNEFGJKF_01508	5.76e-134	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PNEFGJKF_01509	0.0	XK27_08510	-	-	L	-	-	-	Type III restriction protein res subunit
PNEFGJKF_01510	1.6e-69	-	-	-	-	-	-	-	-
PNEFGJKF_01511	9.52e-204	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNEFGJKF_01512	8.27e-189	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PNEFGJKF_01513	3.2e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
PNEFGJKF_01514	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PNEFGJKF_01516	6.17e-236	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
PNEFGJKF_01518	2.7e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PNEFGJKF_01519	3.54e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PNEFGJKF_01520	2.79e-49	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	PFAM Heavy metal transport detoxification protein
PNEFGJKF_01521	2.66e-110	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PNEFGJKF_01522	2.74e-246	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PNEFGJKF_01523	8.72e-50	-	-	-	F	-	-	-	NUDIX domain
PNEFGJKF_01524	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PNEFGJKF_01525	2.66e-117	entB	-	-	Q	-	-	-	Isochorismatase family
PNEFGJKF_01526	0.0	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
PNEFGJKF_01527	4.95e-269	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PNEFGJKF_01528	1.68e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_01529	7.33e-248	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PNEFGJKF_01530	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PNEFGJKF_01531	1.83e-302	-	-	-	-	-	-	-	-
PNEFGJKF_01532	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNEFGJKF_01534	5.72e-239	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PNEFGJKF_01535	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNEFGJKF_01536	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PNEFGJKF_01537	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNEFGJKF_01538	1.91e-261	camS	-	-	S	-	-	-	sex pheromone
PNEFGJKF_01539	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PNEFGJKF_01540	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PNEFGJKF_01541	3.24e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PNEFGJKF_01542	2.36e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PNEFGJKF_01543	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PNEFGJKF_01544	7.72e-181	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
PNEFGJKF_01545	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PNEFGJKF_01546	2.27e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PNEFGJKF_01547	7.76e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PNEFGJKF_01548	3.51e-182	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEFGJKF_01549	1.1e-200	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEFGJKF_01550	2.21e-189	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEFGJKF_01551	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PNEFGJKF_01552	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEFGJKF_01553	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PNEFGJKF_01554	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PNEFGJKF_01555	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PNEFGJKF_01556	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PNEFGJKF_01557	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PNEFGJKF_01558	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PNEFGJKF_01559	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PNEFGJKF_01560	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PNEFGJKF_01561	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PNEFGJKF_01562	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PNEFGJKF_01563	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PNEFGJKF_01564	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PNEFGJKF_01565	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNEFGJKF_01566	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PNEFGJKF_01567	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PNEFGJKF_01568	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PNEFGJKF_01569	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PNEFGJKF_01570	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PNEFGJKF_01571	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PNEFGJKF_01572	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PNEFGJKF_01573	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PNEFGJKF_01574	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PNEFGJKF_01575	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PNEFGJKF_01576	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PNEFGJKF_01577	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PNEFGJKF_01578	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PNEFGJKF_01579	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PNEFGJKF_01580	1.1e-255	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01581	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PNEFGJKF_01582	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PNEFGJKF_01583	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PNEFGJKF_01584	1.44e-155	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PNEFGJKF_01585	3.31e-263	-	-	-	-	-	-	-	-
PNEFGJKF_01586	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEFGJKF_01587	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEFGJKF_01588	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PNEFGJKF_01589	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PNEFGJKF_01590	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PNEFGJKF_01591	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PNEFGJKF_01592	7.53e-191	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PNEFGJKF_01598	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
PNEFGJKF_01599	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01600	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PNEFGJKF_01601	8.71e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PNEFGJKF_01602	2.79e-153	-	-	-	I	-	-	-	phosphatase
PNEFGJKF_01603	2.59e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PNEFGJKF_01604	7.95e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
PNEFGJKF_01605	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PNEFGJKF_01606	2.32e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
PNEFGJKF_01607	1.72e-213	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PNEFGJKF_01608	3.11e-153	-	-	-	S	-	-	-	membrane
PNEFGJKF_01609	4.71e-142	-	-	-	S	-	-	-	VIT family
PNEFGJKF_01610	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
PNEFGJKF_01611	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01612	9.45e-196	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNEFGJKF_01613	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_01614	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_01615	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PNEFGJKF_01616	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNEFGJKF_01617	8.46e-77	-	-	-	-	-	-	-	-
PNEFGJKF_01618	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PNEFGJKF_01619	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PNEFGJKF_01620	6.51e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PNEFGJKF_01621	3.34e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PNEFGJKF_01623	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PNEFGJKF_01624	4.55e-121	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PNEFGJKF_01625	1.16e-242	-	-	-	I	-	-	-	Alpha beta
PNEFGJKF_01626	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01627	2.82e-154	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PNEFGJKF_01628	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PNEFGJKF_01629	5.08e-205	-	-	-	K	-	-	-	LysR family
PNEFGJKF_01630	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PNEFGJKF_01631	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PNEFGJKF_01632	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PNEFGJKF_01633	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PNEFGJKF_01634	1.3e-206	mleR	-	-	K	-	-	-	LysR family
PNEFGJKF_01635	8.22e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEFGJKF_01636	9.87e-266	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
PNEFGJKF_01637	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
PNEFGJKF_01638	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PNEFGJKF_01639	1.19e-31	-	-	-	-	-	-	-	-
PNEFGJKF_01640	8.05e-259	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PNEFGJKF_01641	5.36e-97	-	-	-	-	-	-	-	-
PNEFGJKF_01642	2.79e-294	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PNEFGJKF_01643	1.43e-180	-	-	-	V	-	-	-	Beta-lactamase enzyme family
PNEFGJKF_01644	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PNEFGJKF_01645	5.43e-276	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PNEFGJKF_01646	0.0	arcT	-	-	E	-	-	-	Dipeptidase
PNEFGJKF_01647	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PNEFGJKF_01648	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PNEFGJKF_01649	9.01e-132	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PNEFGJKF_01650	3.74e-212	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PNEFGJKF_01651	6.66e-177	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PNEFGJKF_01652	2.95e-157	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PNEFGJKF_01653	9.06e-125	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PNEFGJKF_01654	1.13e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PNEFGJKF_01655	9.78e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PNEFGJKF_01656	4.85e-296	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PNEFGJKF_01657	1.13e-108	-	-	-	Q	-	-	-	Methyltransferase
PNEFGJKF_01658	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PNEFGJKF_01659	4.98e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PNEFGJKF_01660	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PNEFGJKF_01661	3.28e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PNEFGJKF_01662	1.85e-288	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PNEFGJKF_01663	2.22e-313	-	-	-	M	-	-	-	Glycosyl transferase
PNEFGJKF_01664	6.17e-202	-	-	-	-	-	-	-	-
PNEFGJKF_01665	8.65e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PNEFGJKF_01666	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNEFGJKF_01667	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PNEFGJKF_01668	1.95e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PNEFGJKF_01669	1.71e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PNEFGJKF_01670	7.47e-173	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
PNEFGJKF_01671	6.3e-104	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01672	2.78e-48	-	-	-	L	-	-	-	Transposase
PNEFGJKF_01674	1.66e-247	-	-	-	-	-	-	-	-
PNEFGJKF_01675	4.01e-127	-	-	-	K	-	-	-	acetyltransferase
PNEFGJKF_01676	1.54e-147	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PNEFGJKF_01677	1.93e-210	-	-	-	K	-	-	-	LysR substrate binding domain
PNEFGJKF_01678	2.09e-268	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PNEFGJKF_01679	3.88e-71	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PNEFGJKF_01680	4.54e-241	-	-	-	-	-	-	-	-
PNEFGJKF_01681	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PNEFGJKF_01682	2.66e-235	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PNEFGJKF_01684	1.27e-99	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_01686	1.58e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PNEFGJKF_01687	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PNEFGJKF_01688	2.31e-163	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
PNEFGJKF_01689	2.26e-149	-	-	-	S	-	-	-	Membrane
PNEFGJKF_01690	8.69e-257	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PNEFGJKF_01691	7.98e-223	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
PNEFGJKF_01692	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PNEFGJKF_01693	1.3e-304	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PNEFGJKF_01694	9.92e-53	-	-	-	S	-	-	-	Cytochrome B5
PNEFGJKF_01695	2.54e-36	-	-	-	-	-	-	-	-
PNEFGJKF_01696	3.85e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PNEFGJKF_01697	5.26e-19	-	-	-	-	-	-	-	-
PNEFGJKF_01698	7.09e-273	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
PNEFGJKF_01699	1.52e-125	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
PNEFGJKF_01700	9.83e-106	-	-	-	-	-	-	-	-
PNEFGJKF_01701	1.71e-173	-	-	-	M	-	-	-	Lysin motif
PNEFGJKF_01702	1.97e-257	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01703	5.37e-112	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PNEFGJKF_01704	1.03e-206	-	-	-	J	-	-	-	Methyltransferase
PNEFGJKF_01705	5.16e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PNEFGJKF_01706	1.51e-301	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PNEFGJKF_01707	7.81e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
PNEFGJKF_01709	0.0	-	-	-	-	-	-	-	-
PNEFGJKF_01710	3.94e-221	-	-	-	-	-	-	-	-
PNEFGJKF_01711	1.43e-110	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PNEFGJKF_01712	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PNEFGJKF_01713	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
PNEFGJKF_01714	1.48e-64	-	-	-	V	-	-	-	DNA modification
PNEFGJKF_01715	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PNEFGJKF_01717	4.23e-289	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
PNEFGJKF_01718	2.04e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PNEFGJKF_01719	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PNEFGJKF_01720	6.71e-207	-	-	-	EG	-	-	-	EamA-like transporter family
PNEFGJKF_01721	4.64e-37	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
PNEFGJKF_01722	7.64e-294	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_01723	4.91e-80	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_01724	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PNEFGJKF_01725	8.39e-151	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
PNEFGJKF_01726	1.64e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
PNEFGJKF_01727	1.58e-301	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PNEFGJKF_01728	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
PNEFGJKF_01729	6.22e-10	-	-	-	S	-	-	-	CsbD-like
PNEFGJKF_01730	1.76e-234	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEFGJKF_01731	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PNEFGJKF_01732	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
PNEFGJKF_01733	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
PNEFGJKF_01734	3.42e-195	-	-	-	-	-	-	-	-
PNEFGJKF_01735	1.37e-40	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PNEFGJKF_01736	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PNEFGJKF_01737	5.82e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PNEFGJKF_01738	2.53e-97	-	-	-	F	-	-	-	Nudix hydrolase
PNEFGJKF_01739	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PNEFGJKF_01740	5.29e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PNEFGJKF_01741	1.06e-297	-	-	-	-	-	-	-	-
PNEFGJKF_01742	2.54e-268	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PNEFGJKF_01743	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_01744	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PNEFGJKF_01745	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PNEFGJKF_01746	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PNEFGJKF_01747	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PNEFGJKF_01748	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PNEFGJKF_01749	2.93e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PNEFGJKF_01750	0.0	yagE	-	-	E	-	-	-	amino acid
PNEFGJKF_01751	4.01e-153	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
PNEFGJKF_01752	1.24e-37	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PNEFGJKF_01753	3.33e-33	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01754	6.11e-111	-	-	-	L	-	-	-	Helix-turn-helix domain
PNEFGJKF_01755	1.91e-164	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
PNEFGJKF_01756	1.51e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PNEFGJKF_01757	1.1e-232	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
PNEFGJKF_01758	7.72e-178	-	-	-	IQ	-	-	-	KR domain
PNEFGJKF_01759	1.26e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PNEFGJKF_01760	1.55e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PNEFGJKF_01761	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01762	1.5e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PNEFGJKF_01763	6.5e-71	-	-	-	-	-	-	-	-
PNEFGJKF_01764	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PNEFGJKF_01765	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PNEFGJKF_01766	2.19e-214	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PNEFGJKF_01767	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_01768	1.26e-209	-	-	-	-	-	-	-	-
PNEFGJKF_01769	4.33e-234	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
PNEFGJKF_01770	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
PNEFGJKF_01771	1.18e-271	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01772	4.99e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PNEFGJKF_01773	6.26e-156	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PNEFGJKF_01774	3.18e-11	-	-	-	-	-	-	-	-
PNEFGJKF_01775	4.37e-84	-	-	-	-	-	-	-	-
PNEFGJKF_01776	4.97e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PNEFGJKF_01777	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
PNEFGJKF_01778	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PNEFGJKF_01779	3.22e-215	-	-	-	GK	-	-	-	ROK family
PNEFGJKF_01780	6.47e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PNEFGJKF_01781	8.19e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PNEFGJKF_01782	1.72e-305	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PNEFGJKF_01783	2.71e-181	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PNEFGJKF_01784	3.68e-311	-	-	-	E	-	-	-	amino acid
PNEFGJKF_01785	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PNEFGJKF_01786	2.22e-173	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PNEFGJKF_01787	6.99e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PNEFGJKF_01788	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNEFGJKF_01789	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PNEFGJKF_01790	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01791	4.05e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEFGJKF_01792	4.13e-116	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PNEFGJKF_01793	3.57e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PNEFGJKF_01794	1.6e-247	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
PNEFGJKF_01795	2.5e-171	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
PNEFGJKF_01796	3.23e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
PNEFGJKF_01797	1.05e-176	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PNEFGJKF_01798	1.47e-132	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
PNEFGJKF_01799	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
PNEFGJKF_01800	1.39e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
PNEFGJKF_01801	1.73e-217	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PNEFGJKF_01802	3.46e-303	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PNEFGJKF_01803	9.88e-105	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
PNEFGJKF_01804	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
PNEFGJKF_01805	1.24e-191	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
PNEFGJKF_01806	1.43e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PNEFGJKF_01807	2.56e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PNEFGJKF_01808	4.44e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PNEFGJKF_01809	2.2e-161	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PNEFGJKF_01810	1.51e-188	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
PNEFGJKF_01811	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PNEFGJKF_01812	9.74e-177	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
PNEFGJKF_01813	5.23e-171	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PNEFGJKF_01814	1.55e-250	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
PNEFGJKF_01815	3.02e-176	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PNEFGJKF_01816	1.28e-127	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PNEFGJKF_01817	5.13e-144	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
PNEFGJKF_01818	6.31e-273	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PNEFGJKF_01819	6.88e-160	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
PNEFGJKF_01820	3.27e-229	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PNEFGJKF_01821	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
PNEFGJKF_01822	3.08e-267	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
PNEFGJKF_01823	6.73e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_01824	1.37e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
PNEFGJKF_01825	7.23e-202	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
PNEFGJKF_01826	6.23e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PNEFGJKF_01827	2.69e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
PNEFGJKF_01828	5.79e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
PNEFGJKF_01829	4.9e-158	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
PNEFGJKF_01830	1.7e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
PNEFGJKF_01831	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
PNEFGJKF_01832	1.3e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PNEFGJKF_01833	6.52e-270	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
PNEFGJKF_01834	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
PNEFGJKF_01835	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
PNEFGJKF_01836	1.26e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
PNEFGJKF_01837	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
PNEFGJKF_01838	2.75e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
PNEFGJKF_01839	1.77e-151	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
PNEFGJKF_01840	4.11e-57	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
PNEFGJKF_01841	1.02e-115	-	-	-	CQ	-	-	-	BMC
PNEFGJKF_01842	1.44e-79	pduH	-	-	S	-	-	-	Dehydratase medium subunit
PNEFGJKF_01843	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
PNEFGJKF_01844	5.05e-112	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
PNEFGJKF_01845	1.33e-166	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
PNEFGJKF_01846	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
PNEFGJKF_01847	3.41e-170	pduB	-	-	E	-	-	-	BMC
PNEFGJKF_01848	2.72e-56	-	-	-	CQ	-	-	-	BMC
PNEFGJKF_01849	1.69e-258	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PNEFGJKF_01850	3.27e-192	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
PNEFGJKF_01851	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PNEFGJKF_01852	5.87e-213	-	-	-	-	-	-	-	-
PNEFGJKF_01853	5.33e-208	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PNEFGJKF_01854	2.08e-245	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
PNEFGJKF_01855	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
PNEFGJKF_01856	5.75e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_01857	1.51e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PNEFGJKF_01858	2.93e-119	-	-	-	GM	-	-	-	epimerase
PNEFGJKF_01859	1.51e-202	-	-	-	V	-	-	-	(ABC) transporter
PNEFGJKF_01860	6.04e-309	yhdP	-	-	S	-	-	-	Transporter associated domain
PNEFGJKF_01861	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PNEFGJKF_01862	1.82e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
PNEFGJKF_01863	1.59e-247	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PNEFGJKF_01864	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PNEFGJKF_01865	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PNEFGJKF_01866	3.16e-55	-	-	-	-	-	-	-	-
PNEFGJKF_01867	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PNEFGJKF_01868	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
PNEFGJKF_01869	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
PNEFGJKF_01870	3.7e-297	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNEFGJKF_01871	9.09e-142	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
PNEFGJKF_01872	8.19e-107	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
PNEFGJKF_01873	1.31e-140	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PNEFGJKF_01874	5.06e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PNEFGJKF_01875	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PNEFGJKF_01876	1.08e-289	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PNEFGJKF_01877	7.24e-239	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PNEFGJKF_01878	4.87e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PNEFGJKF_01879	1.65e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PNEFGJKF_01880	1.21e-48	-	-	-	-	-	-	-	-
PNEFGJKF_01881	4.33e-69	-	-	-	-	-	-	-	-
PNEFGJKF_01882	2.72e-262	-	-	-	-	-	-	-	-
PNEFGJKF_01883	8.19e-108	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PNEFGJKF_01884	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PNEFGJKF_01885	2.25e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
PNEFGJKF_01886	6.91e-164	XK27_10500	-	-	K	-	-	-	response regulator
PNEFGJKF_01887	7.79e-236	-	-	-	T	-	-	-	Histidine kinase-like ATPases
PNEFGJKF_01888	5.22e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01889	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PNEFGJKF_01890	1.78e-204	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PNEFGJKF_01891	4.75e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PNEFGJKF_01892	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNEFGJKF_01893	7.66e-255	-	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01894	8.53e-120	ymdB	-	-	S	-	-	-	Macro domain protein
PNEFGJKF_01895	1.03e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PNEFGJKF_01896	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PNEFGJKF_01897	1.48e-64	-	-	-	-	-	-	-	-
PNEFGJKF_01898	2.59e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
PNEFGJKF_01899	3.49e-269	-	-	-	S	-	-	-	associated with various cellular activities
PNEFGJKF_01900	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PNEFGJKF_01901	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PNEFGJKF_01903	2.8e-159	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
PNEFGJKF_01904	8.14e-73	-	-	-	-	-	-	-	-
PNEFGJKF_01906	4.75e-184	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PNEFGJKF_01907	2.48e-66	-	-	-	-	-	-	-	-
PNEFGJKF_01908	5.51e-264	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
PNEFGJKF_01909	2.81e-297	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PNEFGJKF_01910	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PNEFGJKF_01911	1.79e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
PNEFGJKF_01912	1.57e-190	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PNEFGJKF_01913	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PNEFGJKF_01916	1.15e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
PNEFGJKF_01917	3.01e-19	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PNEFGJKF_01919	3.5e-186	-	-	-	M	-	-	-	PFAM NLP P60 protein
PNEFGJKF_01920	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PNEFGJKF_01921	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PNEFGJKF_01922	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01923	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
PNEFGJKF_01924	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PNEFGJKF_01925	6.78e-306	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PNEFGJKF_01926	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PNEFGJKF_01927	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
PNEFGJKF_01928	9.37e-227	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PNEFGJKF_01929	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PNEFGJKF_01930	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PNEFGJKF_01931	5.83e-308	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PNEFGJKF_01932	4.33e-315	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PNEFGJKF_01933	9.6e-317	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PNEFGJKF_01934	5.94e-128	-	-	-	S	-	-	-	Family of unknown function (DUF5449)
PNEFGJKF_01935	2.32e-234	-	4.1.1.22	-	H	ko:K01590	ko00340,ko01100,ko01110,map00340,map01100,map01110	ko00000,ko00001,ko01000	Histidine carboxylase PI chain
PNEFGJKF_01936	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PNEFGJKF_01937	4.98e-89	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PNEFGJKF_01938	2.04e-225	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
PNEFGJKF_01939	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PNEFGJKF_01940	4.03e-163	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
PNEFGJKF_01941	1.77e-56	-	-	-	-	-	-	-	-
PNEFGJKF_01942	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PNEFGJKF_01943	6.52e-270	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
PNEFGJKF_01944	3.54e-181	-	-	-	S	-	-	-	Alpha beta hydrolase
PNEFGJKF_01945	6.17e-281	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PNEFGJKF_01946	3.48e-134	-	-	-	-	-	-	-	-
PNEFGJKF_01948	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PNEFGJKF_01949	1.4e-120	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PNEFGJKF_01950	1.25e-54	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PNEFGJKF_01951	1.34e-145	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PNEFGJKF_01952	1.8e-115	-	-	-	-	-	-	-	-
PNEFGJKF_01953	1.38e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PNEFGJKF_01954	2.7e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
PNEFGJKF_01955	1.52e-148	-	-	-	-	-	-	-	-
PNEFGJKF_01956	2.6e-33	-	-	-	-	-	-	-	-
PNEFGJKF_01957	1.38e-223	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PNEFGJKF_01958	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PNEFGJKF_01959	2.75e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PNEFGJKF_01960	2.89e-51	-	-	-	-	-	-	-	-
PNEFGJKF_01961	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01962	2.58e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PNEFGJKF_01963	2.5e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PNEFGJKF_01964	5.75e-117	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
PNEFGJKF_01965	9.96e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
PNEFGJKF_01966	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PNEFGJKF_01967	2.09e-86	-	-	-	-	-	-	-	-
PNEFGJKF_01968	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PNEFGJKF_01970	5.75e-117	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PNEFGJKF_01971	1.36e-141	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
PNEFGJKF_01972	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PNEFGJKF_01973	4.54e-316	-	-	-	E	ko:K03294	-	ko00000	amino acid
PNEFGJKF_01974	1.46e-236	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PNEFGJKF_01976	2.33e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PNEFGJKF_01977	9.7e-06	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
PNEFGJKF_01978	2.61e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PNEFGJKF_01979	5.47e-55	-	-	-	S	-	-	-	Cytochrome B5
PNEFGJKF_01980	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
PNEFGJKF_01981	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
PNEFGJKF_01982	7.65e-101	-	-	-	S	ko:K02348	-	ko00000	Gnat family
PNEFGJKF_01983	6.67e-158	-	-	-	GM	-	-	-	NmrA-like family
PNEFGJKF_01984	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNEFGJKF_01985	1.41e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PNEFGJKF_01986	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PNEFGJKF_01987	6.82e-309	-	-	-	-	-	-	-	-
PNEFGJKF_01988	2.28e-270	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PNEFGJKF_01989	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PNEFGJKF_01990	6.4e-149	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PNEFGJKF_01991	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PNEFGJKF_01992	1.37e-123	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PNEFGJKF_01993	1.23e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PNEFGJKF_01994	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PNEFGJKF_01995	3.29e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PNEFGJKF_01996	1.75e-263	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PNEFGJKF_01997	7.04e-118	-	-	-	-	-	-	-	-
PNEFGJKF_01998	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PNEFGJKF_01999	1.07e-205	-	-	-	T	-	-	-	EAL domain
PNEFGJKF_02000	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
PNEFGJKF_02001	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
PNEFGJKF_02002	1.74e-85	-	-	-	-	-	-	-	-
PNEFGJKF_02003	1.15e-147	-	-	-	GM	-	-	-	NAD(P)H-binding
PNEFGJKF_02004	6.54e-253	-	-	-	S	-	-	-	membrane
PNEFGJKF_02005	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PNEFGJKF_02006	5.33e-210	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PNEFGJKF_02007	1.64e-203	-	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_02008	3.43e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PNEFGJKF_02009	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PNEFGJKF_02010	1.17e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
PNEFGJKF_02011	2.28e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PNEFGJKF_02012	1.46e-196	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
PNEFGJKF_02013	2.15e-171	-	-	-	S	-	-	-	Alpha beta hydrolase
PNEFGJKF_02014	1.48e-05	-	-	-	S	-	-	-	Hydrolases of the alpha beta superfamily
PNEFGJKF_02015	2.21e-115	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PNEFGJKF_02016	1.35e-206	lysR	-	-	K	-	-	-	Transcriptional regulator
PNEFGJKF_02017	5e-116	-	-	-	C	-	-	-	Flavodoxin
PNEFGJKF_02018	1.16e-14	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
PNEFGJKF_02019	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PNEFGJKF_02020	6.2e-155	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PNEFGJKF_02021	1.21e-292	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PNEFGJKF_02022	3.3e-208	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PNEFGJKF_02023	1.76e-161	-	-	-	H	-	-	-	RibD C-terminal domain
PNEFGJKF_02025	7.86e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic region
PNEFGJKF_02026	5.59e-54	-	-	-	H	-	-	-	RibD C-terminal domain
PNEFGJKF_02027	1.15e-26	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PNEFGJKF_02028	3.43e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
PNEFGJKF_02029	6.53e-118	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
PNEFGJKF_02030	9.8e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PNEFGJKF_02031	5.85e-254	flp	-	-	V	-	-	-	Beta-lactamase
PNEFGJKF_02032	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PNEFGJKF_02033	2.81e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PNEFGJKF_02034	4.91e-156	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PNEFGJKF_02036	7.82e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PNEFGJKF_02037	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
PNEFGJKF_02038	5.61e-156	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
PNEFGJKF_02039	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
PNEFGJKF_02040	0.0	-	-	-	S	-	-	-	amidohydrolase
PNEFGJKF_02041	1.86e-212	-	-	-	S	-	-	-	reductase
PNEFGJKF_02042	2.55e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
PNEFGJKF_02043	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PNEFGJKF_02044	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PNEFGJKF_02045	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PNEFGJKF_02046	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PNEFGJKF_02047	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PNEFGJKF_02048	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PNEFGJKF_02049	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PNEFGJKF_02050	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNEFGJKF_02051	2.41e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PNEFGJKF_02052	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family