ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CLLFOCLF_00006 3.14e-43 - - - L ko:K07484 - ko00000 Transposase IS66 family
CLLFOCLF_00007 7.21e-123 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
CLLFOCLF_00008 1.51e-75 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
CLLFOCLF_00009 1.23e-95 cadD - - P - - - Cadmium resistance transporter
CLLFOCLF_00010 5.12e-08 cadD - - P - - - Cadmium resistance transporter
CLLFOCLF_00011 2.78e-265 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
CLLFOCLF_00012 3.57e-61 - - - S - - - VRR_NUC
CLLFOCLF_00013 1.07e-88 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
CLLFOCLF_00014 1.49e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
CLLFOCLF_00015 1.39e-232 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
CLLFOCLF_00016 6.88e-144 - - - I - - - Acid phosphatase homologues
CLLFOCLF_00017 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
CLLFOCLF_00018 1.91e-108 - - - - - - - -
CLLFOCLF_00019 3.57e-94 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
CLLFOCLF_00020 7.99e-120 - - - - - - - -
CLLFOCLF_00021 1.07e-254 - - - KL - - - DNA methylase
CLLFOCLF_00022 1.73e-67 - - - S - - - Psort location Cytoplasmic, score
CLLFOCLF_00023 3.59e-34 - - - S - - - Domain of unknown function (DUF5049)
CLLFOCLF_00024 0.0 - - - S - - - overlaps another CDS with the same product name
CLLFOCLF_00027 1.33e-15 - - - K - - - Antidote-toxin recognition MazE, bacterial antitoxin
CLLFOCLF_00028 2.89e-276 - - - S - - - Phage portal protein
CLLFOCLF_00029 5.25e-104 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
CLLFOCLF_00030 5.05e-217 - - - S - - - Phage capsid family
CLLFOCLF_00031 1.93e-42 - - - S - - - Phage gp6-like head-tail connector protein
CLLFOCLF_00032 3.47e-61 - - - S - - - Phage head-tail joining protein
CLLFOCLF_00033 8.23e-68 - - - S - - - Bacteriophage holin family
CLLFOCLF_00034 1.12e-10 - - - - - - - -
CLLFOCLF_00035 2.33e-144 - - - L - - - Recombinase zinc beta ribbon domain
CLLFOCLF_00036 1.09e-08 - - - L ko:K06400 - ko00000 Psort location Cytoplasmic, score
CLLFOCLF_00037 1.39e-248 - - - L ko:K06400 - ko00000 Recombinase
CLLFOCLF_00039 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLLFOCLF_00040 7.79e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
CLLFOCLF_00041 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLLFOCLF_00042 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CLLFOCLF_00043 2.75e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLLFOCLF_00044 1.29e-259 camS - - S - - - sex pheromone
CLLFOCLF_00045 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLLFOCLF_00046 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CLLFOCLF_00047 4.55e-267 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLLFOCLF_00048 2.75e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CLLFOCLF_00049 5.09e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
CLLFOCLF_00050 2.58e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
CLLFOCLF_00051 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CLLFOCLF_00052 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLLFOCLF_00053 1.75e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CLLFOCLF_00054 2.89e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLLFOCLF_00055 3.8e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLLFOCLF_00056 2.96e-178 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLLFOCLF_00057 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CLLFOCLF_00058 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLLFOCLF_00059 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLLFOCLF_00060 2.19e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLLFOCLF_00061 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CLLFOCLF_00062 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLLFOCLF_00063 1.51e-159 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CLLFOCLF_00064 8.24e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CLLFOCLF_00065 2.03e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CLLFOCLF_00066 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CLLFOCLF_00067 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLLFOCLF_00068 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLLFOCLF_00069 6.12e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLLFOCLF_00070 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLLFOCLF_00071 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLLFOCLF_00072 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLLFOCLF_00073 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLLFOCLF_00074 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLLFOCLF_00075 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLLFOCLF_00076 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CLLFOCLF_00077 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLLFOCLF_00078 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLLFOCLF_00079 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLLFOCLF_00080 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLLFOCLF_00081 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLLFOCLF_00082 4.22e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CLLFOCLF_00083 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CLLFOCLF_00084 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLLFOCLF_00085 1.75e-63 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CLLFOCLF_00087 1.45e-291 - - - - - - - -
CLLFOCLF_00088 1.39e-82 repB - - L - - - Initiator Replication protein
CLLFOCLF_00090 2.26e-46 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
CLLFOCLF_00091 1e-213 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
CLLFOCLF_00092 1.89e-36 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_00093 8.28e-20 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_00094 2.17e-56 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
CLLFOCLF_00095 2.74e-38 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
CLLFOCLF_00096 1.97e-15 - - - M - - - Rib/alpha-like repeat
CLLFOCLF_00097 0.0 - - - J - - - Elongation factor G, domain IV
CLLFOCLF_00099 3.3e-124 - - - L - - - Integrase
CLLFOCLF_00100 2.2e-70 - - - S - - - Phage derived protein Gp49-like (DUF891)
CLLFOCLF_00101 1.85e-127 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CLLFOCLF_00102 9.83e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
CLLFOCLF_00103 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
CLLFOCLF_00104 2.35e-215 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CLLFOCLF_00105 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CLLFOCLF_00106 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
CLLFOCLF_00107 3.77e-56 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
CLLFOCLF_00108 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
CLLFOCLF_00109 3e-308 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLLFOCLF_00110 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
CLLFOCLF_00111 6.05e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CLLFOCLF_00112 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLLFOCLF_00113 7.51e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLLFOCLF_00114 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLLFOCLF_00115 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLLFOCLF_00116 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLLFOCLF_00117 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLLFOCLF_00118 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CLLFOCLF_00119 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
CLLFOCLF_00120 2.84e-167 yibF - - S - - - overlaps another CDS with the same product name
CLLFOCLF_00121 1.92e-245 yibE - - S - - - overlaps another CDS with the same product name
CLLFOCLF_00122 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLLFOCLF_00123 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLLFOCLF_00124 4.98e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLLFOCLF_00125 6.29e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CLLFOCLF_00126 1.73e-213 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CLLFOCLF_00127 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLLFOCLF_00128 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CLLFOCLF_00129 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
CLLFOCLF_00130 6.91e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
CLLFOCLF_00152 6.97e-27 - - - - - - - -
CLLFOCLF_00161 3.04e-147 dgk2 - - F - - - deoxynucleoside kinase
CLLFOCLF_00162 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
CLLFOCLF_00163 1.69e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CLLFOCLF_00164 6.31e-150 - - - I - - - phosphatase
CLLFOCLF_00165 1.75e-105 - - - S - - - Threonine/Serine exporter, ThrE
CLLFOCLF_00166 2.85e-164 - - - S - - - Putative threonine/serine exporter
CLLFOCLF_00167 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
CLLFOCLF_00168 3.16e-159 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
CLLFOCLF_00169 1.58e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
CLLFOCLF_00170 2.99e-151 - - - S - - - membrane
CLLFOCLF_00171 7.81e-141 - - - S - - - VIT family
CLLFOCLF_00172 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
CLLFOCLF_00173 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_00174 6.38e-194 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLLFOCLF_00175 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_00176 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_00177 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CLLFOCLF_00178 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLLFOCLF_00179 6.7e-74 - - - - - - - -
CLLFOCLF_00180 3.09e-97 - - - K - - - MerR HTH family regulatory protein
CLLFOCLF_00181 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
CLLFOCLF_00182 3.76e-160 - - - S - - - Domain of unknown function (DUF4811)
CLLFOCLF_00183 2.49e-87 yneR - - S - - - Belongs to the HesB IscA family
CLLFOCLF_00184 0.0 - - - S - - - membrane
CLLFOCLF_00185 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CLLFOCLF_00186 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CLLFOCLF_00187 1.61e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLLFOCLF_00188 1.04e-141 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
CLLFOCLF_00189 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
CLLFOCLF_00190 4.16e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
CLLFOCLF_00191 7.66e-88 yqhL - - P - - - Rhodanese-like protein
CLLFOCLF_00192 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
CLLFOCLF_00193 2.99e-219 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLLFOCLF_00194 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CLLFOCLF_00195 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLLFOCLF_00196 8.73e-28 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLLFOCLF_00197 1.28e-18 - - - - - - - -
CLLFOCLF_00198 1.69e-197 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CLLFOCLF_00199 1.11e-128 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLLFOCLF_00200 1.08e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
CLLFOCLF_00201 1.39e-202 - - - - - - - -
CLLFOCLF_00202 2.04e-230 - - - - - - - -
CLLFOCLF_00203 4.54e-111 - - - S - - - Protein conserved in bacteria
CLLFOCLF_00207 7.88e-135 - - - K - - - Transcriptional regulator
CLLFOCLF_00208 1.21e-135 - - - L - - - Integrase
CLLFOCLF_00209 4.34e-45 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
CLLFOCLF_00210 7.42e-59 - - - - - - - -
CLLFOCLF_00212 2.36e-299 - - - - - - - -
CLLFOCLF_00213 2.05e-77 - - - - - - - -
CLLFOCLF_00214 1.99e-38 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
CLLFOCLF_00215 6.57e-121 - - - J - - - Aminoglycoside-2''-adenylyltransferase
CLLFOCLF_00216 1.85e-20 pre - - D - - - plasmid recombination enzyme
CLLFOCLF_00217 3.27e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
CLLFOCLF_00218 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
CLLFOCLF_00219 3.46e-95 - - - F - - - Nudix hydrolase
CLLFOCLF_00220 2.66e-132 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
CLLFOCLF_00221 1.48e-107 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
CLLFOCLF_00222 1.26e-30 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
CLLFOCLF_00223 5.43e-192 - - - - - - - -
CLLFOCLF_00224 5.02e-52 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
CLLFOCLF_00225 7.15e-122 - - - K - - - Transcriptional regulator (TetR family)
CLLFOCLF_00226 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
CLLFOCLF_00227 2.5e-230 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLLFOCLF_00228 1.74e-12 - - - S - - - CsbD-like
CLLFOCLF_00229 1.34e-47 - - - S - - - Transglycosylase associated protein
CLLFOCLF_00230 2.93e-297 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLLFOCLF_00231 1.64e-162 pgm3 - - G - - - phosphoglycerate mutase
CLLFOCLF_00232 1.1e-146 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
CLLFOCLF_00233 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CLLFOCLF_00234 3.89e-49 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
CLLFOCLF_00235 1.45e-201 - - - EG - - - EamA-like transporter family
CLLFOCLF_00236 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CLLFOCLF_00237 2.39e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CLLFOCLF_00238 9.81e-279 - - - S ko:K07133 - ko00000 cog cog1373
CLLFOCLF_00240 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CLLFOCLF_00245 2.87e-42 - - - L ko:K07484 - ko00000 Transposase IS66 family
CLLFOCLF_00246 9.9e-39 - - - L ko:K07484 - ko00000 Transposase IS66 family
CLLFOCLF_00247 9.46e-264 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CLLFOCLF_00248 2.68e-36 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CLLFOCLF_00249 1.62e-178 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
CLLFOCLF_00250 6.62e-177 - - - S - - - Membrane
CLLFOCLF_00251 1.36e-96 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
CLLFOCLF_00252 2.77e-109 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
CLLFOCLF_00253 1.22e-305 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
CLLFOCLF_00254 6e-60 - - - - - - - -
CLLFOCLF_00255 1.95e-109 uspA - - T - - - universal stress protein
CLLFOCLF_00256 3.29e-259 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
CLLFOCLF_00257 2.71e-197 yvgN - - S - - - Aldo keto reductase
CLLFOCLF_00258 2.65e-38 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
CLLFOCLF_00259 1.1e-65 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
CLLFOCLF_00260 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
CLLFOCLF_00261 1.34e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CLLFOCLF_00262 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
CLLFOCLF_00263 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLLFOCLF_00264 1.82e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
CLLFOCLF_00265 7.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CLLFOCLF_00266 2.4e-29 - - - - - - - -
CLLFOCLF_00267 7.9e-130 - - - - - - - -
CLLFOCLF_00269 1.69e-71 - 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NAD(P)H-binding
CLLFOCLF_00271 1.36e-39 - - - S - - - Protein of unknown function (DUF4065)
CLLFOCLF_00272 8.76e-64 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
CLLFOCLF_00273 1.21e-14 - - - - - - - -
CLLFOCLF_00276 1.87e-219 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
CLLFOCLF_00277 6.23e-316 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CLLFOCLF_00279 6.49e-49 - - - - ko:K18829 - ko00000,ko02048 -
CLLFOCLF_00281 0.0 snf - - KL - - - domain protein
CLLFOCLF_00282 6.86e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
CLLFOCLF_00283 1.85e-264 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CLLFOCLF_00284 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
CLLFOCLF_00285 9.38e-22 - - - L - - - nuclease
CLLFOCLF_00286 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CLLFOCLF_00287 5.24e-92 - - - - - - - -
CLLFOCLF_00288 1.95e-131 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
CLLFOCLF_00289 5.6e-158 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CLLFOCLF_00290 1.29e-194 - - - G - - - Belongs to the phosphoglycerate mutase family
CLLFOCLF_00291 4.15e-34 - - - - - - - -
CLLFOCLF_00292 2.52e-186 - - - - - - - -
CLLFOCLF_00294 3.18e-301 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLLFOCLF_00295 1.12e-226 - - - - - - - -
CLLFOCLF_00296 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLLFOCLF_00297 1.17e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
CLLFOCLF_00298 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
CLLFOCLF_00299 1.37e-134 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLLFOCLF_00300 4.6e-249 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
CLLFOCLF_00301 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLLFOCLF_00302 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLLFOCLF_00303 1.15e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLLFOCLF_00304 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLLFOCLF_00305 5.23e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
CLLFOCLF_00306 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLLFOCLF_00307 5.01e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLLFOCLF_00308 1.43e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLLFOCLF_00309 4.96e-127 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CLLFOCLF_00310 3.61e-219 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CLLFOCLF_00311 6.23e-233 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
CLLFOCLF_00312 9.67e-31 rhaS4 - - K - - - helix_turn_helix, arabinose operon control protein
CLLFOCLF_00313 6.08e-164 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
CLLFOCLF_00314 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CLLFOCLF_00315 1.05e-171 - - - L ko:K07487 - ko00000 Transposase
CLLFOCLF_00316 7.44e-82 - - - L ko:K07487 - ko00000 Transposase
CLLFOCLF_00317 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLLFOCLF_00318 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CLLFOCLF_00319 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLLFOCLF_00320 8.83e-141 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
CLLFOCLF_00321 1.38e-158 - - - - - - - -
CLLFOCLF_00322 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLLFOCLF_00323 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLLFOCLF_00324 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
CLLFOCLF_00325 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CLLFOCLF_00326 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
CLLFOCLF_00327 2.56e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
CLLFOCLF_00328 1.36e-198 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
CLLFOCLF_00329 9.29e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CLLFOCLF_00330 2.07e-196 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLLFOCLF_00331 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
CLLFOCLF_00332 3.29e-146 yjbH - - Q - - - Thioredoxin
CLLFOCLF_00333 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CLLFOCLF_00334 6.57e-253 coiA - - S ko:K06198 - ko00000 Competence protein
CLLFOCLF_00335 3.67e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CLLFOCLF_00336 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CLLFOCLF_00337 5.33e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
CLLFOCLF_00338 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CLLFOCLF_00339 2.85e-100 - - - E ko:K03294 - ko00000 amino acid
CLLFOCLF_00340 3.62e-206 - - - E ko:K03294 - ko00000 amino acid
CLLFOCLF_00341 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CLLFOCLF_00342 5.33e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLLFOCLF_00343 5.32e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
CLLFOCLF_00344 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CLLFOCLF_00345 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLLFOCLF_00346 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLLFOCLF_00347 4.05e-258 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CLLFOCLF_00348 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CLLFOCLF_00349 6.38e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CLLFOCLF_00350 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLLFOCLF_00351 4.72e-241 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CLLFOCLF_00352 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLLFOCLF_00353 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
CLLFOCLF_00354 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
CLLFOCLF_00355 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CLLFOCLF_00356 1.57e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CLLFOCLF_00357 4.49e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CLLFOCLF_00358 4.7e-206 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CLLFOCLF_00359 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CLLFOCLF_00360 3.36e-165 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CLLFOCLF_00361 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLLFOCLF_00362 1.43e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLLFOCLF_00363 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLLFOCLF_00364 2.62e-265 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLLFOCLF_00365 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CLLFOCLF_00366 3.59e-147 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CLLFOCLF_00367 7.12e-69 - - - - - - - -
CLLFOCLF_00368 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CLLFOCLF_00369 2.63e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CLLFOCLF_00370 8.04e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
CLLFOCLF_00371 4.13e-197 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CLLFOCLF_00372 1.15e-57 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLLFOCLF_00373 7.97e-280 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLLFOCLF_00374 3.79e-191 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLLFOCLF_00375 3.71e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLLFOCLF_00376 9.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
CLLFOCLF_00377 2.02e-146 - - - J - - - 2'-5' RNA ligase superfamily
CLLFOCLF_00378 4.3e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CLLFOCLF_00379 2.13e-167 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLLFOCLF_00380 5.93e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CLLFOCLF_00381 4.89e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
CLLFOCLF_00382 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CLLFOCLF_00383 6.36e-75 - - - - - - - -
CLLFOCLF_00384 2.71e-51 - - - S - - - Protein of unknown function (DUF1797)
CLLFOCLF_00385 9.33e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLLFOCLF_00386 1.13e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
CLLFOCLF_00387 8.93e-291 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
CLLFOCLF_00388 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLLFOCLF_00389 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
CLLFOCLF_00390 5.62e-37 - - - - - - - -
CLLFOCLF_00391 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
CLLFOCLF_00392 1.56e-130 - - - S - - - Pfam:DUF3816
CLLFOCLF_00393 5.49e-182 - - - G - - - MucBP domain
CLLFOCLF_00394 1.17e-147 - - - - - - - -
CLLFOCLF_00395 1.27e-185 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_00397 6.47e-121 - - - L - - - Integrase
CLLFOCLF_00400 1.29e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
CLLFOCLF_00401 2.41e-44 - - - - - - - -
CLLFOCLF_00402 3.1e-06 - - - L - - - Resolvase, N terminal domain
CLLFOCLF_00403 9.11e-54 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
CLLFOCLF_00404 0.0 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
CLLFOCLF_00405 1.41e-67 - - - - - - - -
CLLFOCLF_00407 2.56e-17 - - - - - - - -
CLLFOCLF_00409 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
CLLFOCLF_00410 7.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
CLLFOCLF_00411 2.9e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
CLLFOCLF_00412 3.01e-145 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
CLLFOCLF_00413 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
CLLFOCLF_00414 3.65e-273 - - - G - - - Transporter, major facilitator family protein
CLLFOCLF_00415 2.88e-141 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
CLLFOCLF_00416 4.2e-79 yuxO - - Q - - - Thioesterase superfamily
CLLFOCLF_00417 1.16e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLLFOCLF_00418 1.38e-42 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
CLLFOCLF_00419 2.84e-42 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
CLLFOCLF_00420 1.56e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
CLLFOCLF_00421 1.66e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
CLLFOCLF_00422 7.46e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLLFOCLF_00423 1.24e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
CLLFOCLF_00424 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
CLLFOCLF_00425 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
CLLFOCLF_00426 1.83e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
CLLFOCLF_00427 2.05e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
CLLFOCLF_00429 5.83e-51 - - - S - - - Cytochrome B5
CLLFOCLF_00430 5.7e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
CLLFOCLF_00431 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
CLLFOCLF_00432 1.54e-191 - - - O - - - Band 7 protein
CLLFOCLF_00433 7.5e-56 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
CLLFOCLF_00434 1.22e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CLLFOCLF_00435 7.04e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
CLLFOCLF_00436 3.18e-237 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
CLLFOCLF_00437 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
CLLFOCLF_00438 6.66e-48 - - - L - - - Transposase
CLLFOCLF_00439 4.26e-109 - - - - - - - -
CLLFOCLF_00440 4.39e-213 int7 - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00441 2.31e-27 - - - S - - - DNA binding domain, excisionase family
CLLFOCLF_00444 3.18e-160 - - - - - - - -
CLLFOCLF_00445 3.28e-15 - - - S - - - Helix-turn-helix domain
CLLFOCLF_00447 5.22e-101 tnpR1 - - L - - - Resolvase, N terminal domain
CLLFOCLF_00451 4.25e-153 - - - L ko:K07497 - ko00000 hmm pf00665
CLLFOCLF_00452 8.15e-136 - - - L - - - Helix-turn-helix domain
CLLFOCLF_00453 1.45e-112 - - - - - - - -
CLLFOCLF_00454 6.4e-97 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH nucleases
CLLFOCLF_00455 3.28e-128 - - - - - - - -
CLLFOCLF_00456 9.68e-292 - - - KL - - - DNA methylase
CLLFOCLF_00457 4.19e-146 - - - S - - - Psort location Cytoplasmic, score
CLLFOCLF_00458 8.38e-42 - - - S - - - Domain of unknown function (DUF5049)
CLLFOCLF_00459 0.0 - - - S - - - overlaps another CDS with the same product name
CLLFOCLF_00460 2.37e-310 - - - S - - - Phage portal protein
CLLFOCLF_00461 4.66e-156 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
CLLFOCLF_00462 1.29e-281 - - - S - - - Phage capsid family
CLLFOCLF_00463 2.17e-57 - - - S - - - Phage gp6-like head-tail connector protein
CLLFOCLF_00464 1.29e-88 - - - S - - - Phage head-tail joining protein
CLLFOCLF_00465 5.95e-92 - - - S - - - Bacteriophage holin family
CLLFOCLF_00466 1.29e-26 - - - M - - - Glycosyl hydrolases family 25
CLLFOCLF_00467 9.33e-89 - - - M - - - Glycosyl hydrolases family 25
CLLFOCLF_00468 1.03e-37 - - - - - - - -
CLLFOCLF_00469 0.0 - - - L - - - Recombinase zinc beta ribbon domain
CLLFOCLF_00470 0.0 - - - L - - - Recombinase
CLLFOCLF_00471 9.37e-163 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLLFOCLF_00472 2.68e-162 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
CLLFOCLF_00473 8.37e-87 - - - K - - - LytTr DNA-binding domain
CLLFOCLF_00474 1.87e-52 - - - S - - - Protein of unknown function (DUF3021)
CLLFOCLF_00476 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
CLLFOCLF_00477 3.38e-57 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
CLLFOCLF_00478 1.27e-223 - - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00479 1.04e-46 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CLLFOCLF_00480 9.1e-39 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CLLFOCLF_00481 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
CLLFOCLF_00482 4.26e-32 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLLFOCLF_00483 4.52e-137 - - - F - - - helicase superfamily c-terminal domain
CLLFOCLF_00486 6.8e-32 - - - - - - - -
CLLFOCLF_00487 3.92e-38 - - - - - - - -
CLLFOCLF_00488 4.28e-255 - - - L - - - Protein of unknown function (DUF2800)
CLLFOCLF_00489 2.16e-122 - - - S - - - Protein of unknown function (DUF2815)
CLLFOCLF_00490 1.41e-54 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
CLLFOCLF_00491 1.06e-92 - - - S - - - Psort location Cytoplasmic, score
CLLFOCLF_00492 1.81e-119 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
CLLFOCLF_00493 2.94e-60 - - - S - - - VRR_NUC
CLLFOCLF_00494 1.33e-179 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
CLLFOCLF_00495 2.07e-285 - - - G - - - Glycosyl hydrolases family 8
CLLFOCLF_00496 2.77e-307 - - - M - - - Glycosyl transferase
CLLFOCLF_00498 5.82e-191 - - - - - - - -
CLLFOCLF_00499 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
CLLFOCLF_00500 1.28e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLLFOCLF_00501 2.77e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CLLFOCLF_00502 1.71e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CLLFOCLF_00503 8.8e-73 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
CLLFOCLF_00504 6.92e-130 - - - S - - - Protein of unknown function (DUF1461)
CLLFOCLF_00505 6.76e-170 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CLLFOCLF_00506 2.66e-120 yutD - - S - - - Protein of unknown function (DUF1027)
CLLFOCLF_00507 1.21e-143 - - - S - - - Calcineurin-like phosphoesterase
CLLFOCLF_00508 4.36e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLLFOCLF_00509 9.39e-192 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
CLLFOCLF_00510 5.18e-89 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
CLLFOCLF_00511 1.96e-55 - - - - - - - -
CLLFOCLF_00512 2.38e-99 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
CLLFOCLF_00513 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
CLLFOCLF_00514 2.13e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
CLLFOCLF_00515 9.82e-234 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
CLLFOCLF_00516 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
CLLFOCLF_00517 6.37e-176 - - - - - - - -
CLLFOCLF_00518 7.72e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CLLFOCLF_00519 1.72e-266 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
CLLFOCLF_00520 2.04e-72 - - - - - - - -
CLLFOCLF_00521 8.88e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CLLFOCLF_00522 7.58e-189 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
CLLFOCLF_00523 1.83e-196 - - - S - - - haloacid dehalogenase-like hydrolase
CLLFOCLF_00524 8.55e-99 ykuL - - S - - - (CBS) domain
CLLFOCLF_00525 6.71e-120 - - - S ko:K07095 - ko00000 Phosphoesterase
CLLFOCLF_00526 4.22e-136 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLLFOCLF_00527 6.89e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CLLFOCLF_00528 1.74e-125 yslB - - S - - - Protein of unknown function (DUF2507)
CLLFOCLF_00529 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CLLFOCLF_00530 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CLLFOCLF_00531 7.15e-122 cvpA - - S - - - Colicin V production protein
CLLFOCLF_00532 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
CLLFOCLF_00533 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLLFOCLF_00534 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
CLLFOCLF_00535 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLLFOCLF_00536 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CLLFOCLF_00537 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
CLLFOCLF_00538 1.44e-59 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
CLLFOCLF_00539 2.41e-239 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CLLFOCLF_00540 1.36e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CLLFOCLF_00541 4.34e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CLLFOCLF_00542 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLLFOCLF_00543 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLLFOCLF_00544 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CLLFOCLF_00545 5.17e-250 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLLFOCLF_00546 2.18e-287 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
CLLFOCLF_00547 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLLFOCLF_00548 3.1e-192 - - - S - - - Helix-turn-helix domain
CLLFOCLF_00549 3.66e-315 ymfH - - S - - - Peptidase M16
CLLFOCLF_00550 2.28e-289 ymfF - - S - - - Peptidase M16 inactive domain protein
CLLFOCLF_00551 5.91e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_00552 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CLLFOCLF_00553 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
CLLFOCLF_00554 3.82e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CLLFOCLF_00555 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
CLLFOCLF_00556 4.2e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
CLLFOCLF_00557 9.28e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CLLFOCLF_00558 1.81e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CLLFOCLF_00559 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLLFOCLF_00560 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CLLFOCLF_00561 5.45e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
CLLFOCLF_00562 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
CLLFOCLF_00563 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CLLFOCLF_00564 2.37e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLLFOCLF_00565 7.1e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CLLFOCLF_00566 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CLLFOCLF_00567 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLLFOCLF_00576 1.12e-167 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
CLLFOCLF_00577 3.64e-175 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
CLLFOCLF_00578 1.45e-184 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLLFOCLF_00579 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
CLLFOCLF_00580 2.29e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLLFOCLF_00581 4.19e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CLLFOCLF_00582 2.73e-283 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CLLFOCLF_00583 8.85e-160 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CLLFOCLF_00584 2.72e-194 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
CLLFOCLF_00585 1.99e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLLFOCLF_00586 1.46e-214 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLLFOCLF_00587 3.21e-99 - - - K - - - Transcriptional regulator, MarR family
CLLFOCLF_00588 1.39e-91 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLLFOCLF_00590 3.42e-258 xerS - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00591 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
CLLFOCLF_00592 7.53e-20 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
CLLFOCLF_00593 1.15e-200 rssA - - S - - - Phospholipase, patatin family
CLLFOCLF_00594 9.45e-152 - - - L - - - Integrase
CLLFOCLF_00595 1.88e-196 - - - EG - - - EamA-like transporter family
CLLFOCLF_00596 3.85e-167 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
CLLFOCLF_00597 2.57e-70 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
CLLFOCLF_00598 9.62e-45 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
CLLFOCLF_00599 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
CLLFOCLF_00600 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLLFOCLF_00601 1.65e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
CLLFOCLF_00602 3.34e-286 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
CLLFOCLF_00603 2.25e-97 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
CLLFOCLF_00604 4.55e-124 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CLLFOCLF_00605 1.61e-291 - - - P - - - Chloride transporter, ClC family
CLLFOCLF_00606 7.39e-184 - - - L - - - PFAM transposase IS116 IS110 IS902
CLLFOCLF_00607 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
CLLFOCLF_00608 6.1e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLLFOCLF_00609 1.34e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
CLLFOCLF_00610 2.34e-265 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
CLLFOCLF_00611 2.78e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CLLFOCLF_00612 1.74e-101 - - - - - - - -
CLLFOCLF_00613 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
CLLFOCLF_00614 4.14e-230 - - - I - - - Diacylglycerol kinase catalytic
CLLFOCLF_00615 8.83e-39 - - - - - - - -
CLLFOCLF_00616 1.18e-215 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
CLLFOCLF_00618 2.15e-75 - - - - - - - -
CLLFOCLF_00619 1.25e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CLLFOCLF_00620 1.1e-279 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
CLLFOCLF_00621 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
CLLFOCLF_00622 4.47e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLLFOCLF_00623 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLLFOCLF_00624 1.82e-180 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CLLFOCLF_00625 6.29e-221 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLLFOCLF_00626 2.32e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CLLFOCLF_00627 2.18e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CLLFOCLF_00628 1.33e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CLLFOCLF_00629 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CLLFOCLF_00630 2.6e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLLFOCLF_00631 1.66e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLLFOCLF_00632 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CLLFOCLF_00633 4.96e-21 - - - S - - - repeat protein
CLLFOCLF_00634 5.71e-159 pgm6 - - G - - - phosphoglycerate mutase
CLLFOCLF_00635 6.17e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CLLFOCLF_00636 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
CLLFOCLF_00637 1.1e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
CLLFOCLF_00638 1.62e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLLFOCLF_00639 1.19e-25 - - - - - - - -
CLLFOCLF_00640 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CLLFOCLF_00641 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
CLLFOCLF_00642 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLLFOCLF_00643 7.24e-100 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
CLLFOCLF_00644 2.5e-188 ylmH - - S - - - S4 domain protein
CLLFOCLF_00645 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
CLLFOCLF_00646 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CLLFOCLF_00647 4.88e-283 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLLFOCLF_00648 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CLLFOCLF_00649 3.33e-183 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CLLFOCLF_00650 1.98e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLLFOCLF_00651 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLLFOCLF_00652 7.73e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLLFOCLF_00653 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CLLFOCLF_00654 9.94e-73 ftsL - - D - - - Cell division protein FtsL
CLLFOCLF_00655 4.95e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CLLFOCLF_00656 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CLLFOCLF_00657 2.32e-75 - - - - - - - -
CLLFOCLF_00658 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
CLLFOCLF_00659 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CLLFOCLF_00660 1.53e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CLLFOCLF_00661 6.7e-205 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
CLLFOCLF_00662 2.67e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
CLLFOCLF_00664 1.45e-225 - - - L ko:K07484 - ko00000 Transposase IS66 family
CLLFOCLF_00665 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
CLLFOCLF_00666 8.03e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
CLLFOCLF_00667 3.05e-91 - - - S - - - Psort location Cytoplasmic, score
CLLFOCLF_00668 1.57e-127 - - - S - - - Protein of unknown function (DUF2815)
CLLFOCLF_00669 1.48e-269 - - - L - - - Protein of unknown function (DUF2800)
CLLFOCLF_00670 2.17e-54 - - - - - - - -
CLLFOCLF_00671 5.78e-35 - - - - - - - -
CLLFOCLF_00672 5.68e-95 - - - K - - - DNA-templated transcription, initiation
CLLFOCLF_00674 5.03e-161 - - - F - - - helicase superfamily c-terminal domain
CLLFOCLF_00675 2.65e-32 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLLFOCLF_00676 9.64e-92 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
CLLFOCLF_00677 4.31e-180 - - - L - - - Bacterial dnaA protein
CLLFOCLF_00678 3.28e-222 - - - L - - - Integrase core domain
CLLFOCLF_00679 2.51e-107 - - - L - - - site-specific DNA-methyltransferase (adenine-specific) activity
CLLFOCLF_00680 0.0 - - - L - - - Type III restriction enzyme, res subunit
CLLFOCLF_00681 0.0 - - - S - - - Protein of unknown function DUF262
CLLFOCLF_00683 7.25e-31 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
CLLFOCLF_00684 1.13e-70 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLLFOCLF_00685 1.63e-233 - - - S - - - Domain of unknown function (DUF389)
CLLFOCLF_00686 1.6e-110 - - - L ko:K06400 - ko00000 Recombinase
CLLFOCLF_00687 5.15e-94 - - - K - - - DNA binding
CLLFOCLF_00688 6.86e-150 - - - L - - - helicase activity
CLLFOCLF_00689 1.76e-260 - - - L - - - helicase activity
CLLFOCLF_00691 1.03e-72 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_00692 8.93e-210 - - - L - - - PFAM Integrase catalytic region
CLLFOCLF_00693 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
CLLFOCLF_00694 1.35e-46 - - - C - - - Heavy-metal-associated domain
CLLFOCLF_00695 5.23e-123 dpsB - - P - - - Belongs to the Dps family
CLLFOCLF_00696 4.13e-147 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
CLLFOCLF_00697 2.1e-145 ung2 - - L - - - Uracil-DNA glycosylase
CLLFOCLF_00698 6.94e-80 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
CLLFOCLF_00699 1.19e-31 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
CLLFOCLF_00700 8.59e-86 - - - L ko:K06400 - ko00000 Recombinase
CLLFOCLF_00701 8.29e-83 - - - L ko:K06400 - ko00000 Recombinase
CLLFOCLF_00702 2.05e-105 - - - L - - - Recombinase
CLLFOCLF_00703 2.87e-32 - - - L - - - Recombinase zinc beta ribbon domain
CLLFOCLF_00704 9.73e-85 - - - L - - - Recombinase zinc beta ribbon domain
CLLFOCLF_00705 1.13e-26 - - - - - - - -
CLLFOCLF_00706 1.89e-38 - - - S - - - Bacteriophage holin family
CLLFOCLF_00707 2.78e-71 - - - S - - - Phage head-tail joining protein
CLLFOCLF_00708 1.16e-52 - - - S - - - Phage gp6-like head-tail connector protein
CLLFOCLF_00709 8.27e-235 - - - S - - - Phage capsid family
CLLFOCLF_00710 1.27e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLLFOCLF_00711 8.85e-164 - - - F - - - NUDIX domain
CLLFOCLF_00712 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLLFOCLF_00713 3.18e-133 pncA - - Q - - - Isochorismatase family
CLLFOCLF_00714 3.4e-145 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
CLLFOCLF_00715 1.22e-100 - - - I - - - alpha/beta hydrolase fold
CLLFOCLF_00716 2.05e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
CLLFOCLF_00717 8.5e-41 - - - S - - - Phage derived protein Gp49-like (DUF891)
CLLFOCLF_00719 1.37e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
CLLFOCLF_00720 8.29e-194 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
CLLFOCLF_00721 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
CLLFOCLF_00722 1.15e-25 - - - - - - - -
CLLFOCLF_00723 8.51e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
CLLFOCLF_00724 8.42e-149 - - - S - - - Protein of unknown function (DUF421)
CLLFOCLF_00725 3.91e-95 - - - S - - - Protein of unknown function (DUF3290)
CLLFOCLF_00726 8.32e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
CLLFOCLF_00727 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLLFOCLF_00728 8.11e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
CLLFOCLF_00729 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
CLLFOCLF_00731 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLLFOCLF_00732 7.36e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
CLLFOCLF_00733 3.25e-155 - - - S - - - SNARE associated Golgi protein
CLLFOCLF_00734 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
CLLFOCLF_00735 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLLFOCLF_00736 4.18e-75 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLLFOCLF_00737 2.79e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLLFOCLF_00738 1.82e-186 - - - S - - - DUF218 domain
CLLFOCLF_00739 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
CLLFOCLF_00740 2.2e-315 yhdP - - S - - - Transporter associated domain
CLLFOCLF_00741 3.97e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
CLLFOCLF_00742 2.65e-305 - - - U - - - Belongs to the major facilitator superfamily
CLLFOCLF_00743 3.18e-96 - - - S - - - UPF0756 membrane protein
CLLFOCLF_00744 5.42e-105 - - - C - - - Flavodoxin
CLLFOCLF_00745 9.48e-205 rlrB - - K - - - LysR substrate binding domain protein
CLLFOCLF_00746 4.38e-211 yvgN - - C - - - Aldo keto reductase
CLLFOCLF_00747 5.51e-90 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
CLLFOCLF_00748 1.39e-90 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
CLLFOCLF_00749 7.5e-122 - - - K - - - Acetyltransferase (GNAT) domain
CLLFOCLF_00750 2.93e-197 - - - S - - - Alpha beta hydrolase
CLLFOCLF_00751 8.1e-200 gspA - - M - - - family 8
CLLFOCLF_00752 9.78e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CLLFOCLF_00753 1.38e-119 - - - - - - - -
CLLFOCLF_00754 9.88e-206 - - - S - - - EDD domain protein, DegV family
CLLFOCLF_00755 0.0 FbpA - - K - - - Fibronectin-binding protein
CLLFOCLF_00756 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CLLFOCLF_00757 1.3e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
CLLFOCLF_00758 4.61e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CLLFOCLF_00759 1.26e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLLFOCLF_00760 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
CLLFOCLF_00761 1.55e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
CLLFOCLF_00762 5.93e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CLLFOCLF_00763 1.62e-106 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
CLLFOCLF_00764 3.25e-72 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CLLFOCLF_00765 4.8e-130 ypsA - - S - - - Belongs to the UPF0398 family
CLLFOCLF_00766 2.01e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CLLFOCLF_00767 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
CLLFOCLF_00768 2.32e-206 - - - EG - - - EamA-like transporter family
CLLFOCLF_00769 7.96e-158 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
CLLFOCLF_00770 4.69e-115 ypmB - - S - - - Protein conserved in bacteria
CLLFOCLF_00771 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CLLFOCLF_00772 2.86e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
CLLFOCLF_00773 8.5e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
CLLFOCLF_00774 1.13e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
CLLFOCLF_00775 3.63e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CLLFOCLF_00776 2.78e-118 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
CLLFOCLF_00777 1.05e-45 - - - - - - - -
CLLFOCLF_00778 8.66e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
CLLFOCLF_00779 3.75e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CLLFOCLF_00780 1.86e-14 - - - - - - - -
CLLFOCLF_00781 3.18e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CLLFOCLF_00782 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
CLLFOCLF_00783 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
CLLFOCLF_00784 1.55e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CLLFOCLF_00785 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
CLLFOCLF_00786 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CLLFOCLF_00787 2.11e-290 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
CLLFOCLF_00788 2.87e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
CLLFOCLF_00789 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLLFOCLF_00791 1.83e-143 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
CLLFOCLF_00792 5.58e-192 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CLLFOCLF_00793 5.4e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
CLLFOCLF_00794 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
CLLFOCLF_00795 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CLLFOCLF_00796 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
CLLFOCLF_00797 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
CLLFOCLF_00798 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLLFOCLF_00799 7.88e-116 - - - - - - - -
CLLFOCLF_00800 3.82e-47 - - - - - - - -
CLLFOCLF_00801 5.26e-12 - - - K - - - Transcriptional regulator, HxlR family
CLLFOCLF_00802 1.11e-218 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CLLFOCLF_00803 4.78e-192 epsB - - M - - - biosynthesis protein
CLLFOCLF_00804 9.35e-155 ywqD - - D - - - Capsular exopolysaccharide family
CLLFOCLF_00805 9.65e-176 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
CLLFOCLF_00806 1e-114 tuaA - - M - - - Bacterial sugar transferase
CLLFOCLF_00807 6.93e-51 - - - M - - - Glycosyltransferase like family 2
CLLFOCLF_00808 1.65e-27 rfaG - - M - - - Glycosyltransferase like family 2
CLLFOCLF_00809 1.55e-60 - - - M - - - Glycosyl transferases group 1
CLLFOCLF_00810 2.32e-42 - - - S - - - Glycosyltransferase like family 2
CLLFOCLF_00811 1.45e-71 - - - M - - - Glycosyltransferase like family 2
CLLFOCLF_00813 6.68e-134 - - - S - - - Polysaccharide biosynthesis protein
CLLFOCLF_00814 6.75e-20 waaD 2.4.1.56 GT4,GT9 M ko:K00713,ko:K00754,ko:K03280 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
CLLFOCLF_00815 5.02e-89 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CLLFOCLF_00816 3.69e-106 - 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
CLLFOCLF_00817 1.7e-121 - - - M - - - Male sterility protein
CLLFOCLF_00818 1.49e-87 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CLLFOCLF_00819 3.72e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CLLFOCLF_00821 2e-207 - - - L - - - Integrase core domain
CLLFOCLF_00822 9.79e-72 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CLLFOCLF_00824 9.53e-92 - - - S - - - SIR2-like domain
CLLFOCLF_00825 3.09e-122 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
CLLFOCLF_00826 1.62e-52 - - - M - - - Rib/alpha-like repeat
CLLFOCLF_00833 8.32e-104 ydcL - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00834 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
CLLFOCLF_00837 2.21e-101 tnpR1 - - L - - - Resolvase, N terminal domain
CLLFOCLF_00838 2.22e-163 - - - - - - - -
CLLFOCLF_00839 0.0 - - - - - - - -
CLLFOCLF_00841 1.11e-45 - - - S - - - Domain of unknown function (DUF3173)
CLLFOCLF_00842 1.74e-291 - - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00843 1.48e-288 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
CLLFOCLF_00844 1.2e-205 - - - J - - - Methyltransferase
CLLFOCLF_00845 2.12e-119 ywlG - - S - - - Belongs to the UPF0340 family
CLLFOCLF_00846 1.32e-55 - - - K - - - PFAM GCN5-related N-acetyltransferase
CLLFOCLF_00847 1.04e-43 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CLLFOCLF_00848 1.52e-50 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CLLFOCLF_00849 2.83e-263 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
CLLFOCLF_00850 3.7e-19 - - - - - - - -
CLLFOCLF_00851 5.75e-52 - - - S - - - Cytochrome B5
CLLFOCLF_00853 1.59e-47 - - - L - - - Helix-turn-helix domain
CLLFOCLF_00855 4.12e-157 - - - O - - - Zinc-dependent metalloprotease
CLLFOCLF_00856 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CLLFOCLF_00857 1.3e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CLLFOCLF_00859 7.11e-08 - - - NU - - - Mycoplasma protein of unknown function, DUF285
CLLFOCLF_00860 3.47e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
CLLFOCLF_00861 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLLFOCLF_00862 1.07e-239 - - - - - - - -
CLLFOCLF_00863 6.73e-81 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_00864 1.71e-89 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
CLLFOCLF_00865 5.11e-107 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CLLFOCLF_00866 2.32e-126 - - - K - - - acetyltransferase
CLLFOCLF_00867 6.97e-240 - - - - - - - -
CLLFOCLF_00869 3.93e-48 - - - L - - - Transposase
CLLFOCLF_00870 8.03e-44 - - - L - - - Transposase
CLLFOCLF_00871 2.64e-20 - - - L - - - Transposase
CLLFOCLF_00872 7.7e-57 - - - L - - - Transposase
CLLFOCLF_00873 6.03e-221 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLLFOCLF_00874 8.5e-63 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CLLFOCLF_00875 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CLLFOCLF_00876 6.21e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLLFOCLF_00877 9.26e-218 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLLFOCLF_00878 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLLFOCLF_00879 8.67e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
CLLFOCLF_00880 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CLLFOCLF_00881 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
CLLFOCLF_00882 2.4e-73 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CLLFOCLF_00883 4.11e-52 yabO - - J - - - S4 domain protein
CLLFOCLF_00884 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLLFOCLF_00885 3.25e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CLLFOCLF_00886 2.7e-145 - - - S - - - (CBS) domain
CLLFOCLF_00887 8.04e-186 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
CLLFOCLF_00888 1.59e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
CLLFOCLF_00889 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
CLLFOCLF_00890 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
CLLFOCLF_00891 2.85e-265 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLLFOCLF_00892 8.96e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CLLFOCLF_00893 4.54e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
CLLFOCLF_00894 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLLFOCLF_00895 1.1e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
CLLFOCLF_00896 5.82e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLLFOCLF_00897 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLLFOCLF_00898 9.92e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CLLFOCLF_00899 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CLLFOCLF_00900 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CLLFOCLF_00901 2.14e-203 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CLLFOCLF_00902 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
CLLFOCLF_00903 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_00904 7.48e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
CLLFOCLF_00905 5.32e-208 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
CLLFOCLF_00906 1.67e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLLFOCLF_00907 8.49e-191 - - - G - - - Right handed beta helix region
CLLFOCLF_00908 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CLLFOCLF_00909 1.18e-159 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
CLLFOCLF_00910 1.78e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
CLLFOCLF_00911 2.16e-301 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLLFOCLF_00912 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CLLFOCLF_00913 1.11e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLLFOCLF_00914 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CLLFOCLF_00915 2.44e-84 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CLLFOCLF_00916 3.15e-71 ywiB - - S - - - Domain of unknown function (DUF1934)
CLLFOCLF_00917 3.54e-190 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
CLLFOCLF_00918 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
CLLFOCLF_00919 3.14e-188 yidA - - S - - - hydrolase
CLLFOCLF_00920 1.19e-98 - - - - - - - -
CLLFOCLF_00921 2.04e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLLFOCLF_00922 3.04e-312 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLLFOCLF_00923 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CLLFOCLF_00924 6.12e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
CLLFOCLF_00925 1.98e-157 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CLLFOCLF_00926 2.75e-213 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CLLFOCLF_00927 6.98e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLLFOCLF_00928 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
CLLFOCLF_00929 4.17e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CLLFOCLF_00930 4.96e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLLFOCLF_00931 1.46e-197 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
CLLFOCLF_00932 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLLFOCLF_00933 3.2e-206 yunF - - F - - - Protein of unknown function DUF72
CLLFOCLF_00935 8.39e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
CLLFOCLF_00936 1.05e-225 - - - - - - - -
CLLFOCLF_00937 7.91e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
CLLFOCLF_00938 4.38e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
CLLFOCLF_00939 2.26e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CLLFOCLF_00940 8.74e-234 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
CLLFOCLF_00941 4.08e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
CLLFOCLF_00942 0.0 - - - L - - - DNA helicase
CLLFOCLF_00943 1.29e-259 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CLLFOCLF_00945 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLLFOCLF_00946 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
CLLFOCLF_00947 1.64e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLLFOCLF_00948 5.74e-54 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
CLLFOCLF_00949 1.7e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
CLLFOCLF_00950 2.32e-212 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
CLLFOCLF_00951 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CLLFOCLF_00952 3.47e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLLFOCLF_00953 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_00954 2.08e-19 eriC - - P ko:K03281 - ko00000 chloride
CLLFOCLF_00955 8.8e-121 eriC - - P ko:K03281 - ko00000 chloride
CLLFOCLF_00956 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CLLFOCLF_00957 1.32e-136 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
CLLFOCLF_00958 3.69e-183 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_00959 6.73e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_00960 1.85e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
CLLFOCLF_00961 1.06e-94 ywnA - - K - - - Transcriptional regulator
CLLFOCLF_00962 1.08e-65 - - - GM - - - NAD(P)H-binding
CLLFOCLF_00963 2.68e-45 - - - GM - - - NAD(P)H-binding
CLLFOCLF_00964 4.44e-11 - - - - - - - -
CLLFOCLF_00965 6.94e-281 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
CLLFOCLF_00966 0.0 cadA - - P - - - P-type ATPase
CLLFOCLF_00967 4.58e-162 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
CLLFOCLF_00968 2.12e-162 - - - - - - - -
CLLFOCLF_00969 1.85e-69 - - - S - - - Sugar efflux transporter for intercellular exchange
CLLFOCLF_00970 1.28e-311 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
CLLFOCLF_00972 0.0 - - - L - - - Helicase C-terminal domain protein
CLLFOCLF_00973 1.2e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
CLLFOCLF_00974 2.3e-228 ydhF - - S - - - Aldo keto reductase
CLLFOCLF_00976 2.58e-36 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
CLLFOCLF_00977 1.34e-127 - - - S ko:K07002 - ko00000 Serine hydrolase
CLLFOCLF_00979 9.35e-231 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLLFOCLF_00980 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
CLLFOCLF_00981 1.83e-49 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
CLLFOCLF_00982 7.28e-139 - - - S ko:K07118 - ko00000 NAD(P)H-binding
CLLFOCLF_00983 5.26e-152 - - - L - - - PFAM Integrase catalytic region
CLLFOCLF_00986 1.93e-224 - - - S - - - Conserved hypothetical protein 698
CLLFOCLF_00987 4.2e-186 - - - K - - - LysR substrate binding domain
CLLFOCLF_00988 2.93e-125 - - - V - - - VanZ like family
CLLFOCLF_00989 1.02e-08 - - - - - - - -
CLLFOCLF_00990 4.51e-32 - - - - - - - -
CLLFOCLF_00992 2.47e-186 - - - L - - - Transposase and inactivated derivatives IS30 family
CLLFOCLF_00994 2.16e-143 - - - S - - - Fic/DOC family
CLLFOCLF_00995 1.19e-160 - - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_00996 3.83e-26 - - - - - - - -
CLLFOCLF_00999 3.41e-181 - - - - - - - -
CLLFOCLF_01001 3.78e-98 tnpR1 - - L - - - Resolvase, N terminal domain
CLLFOCLF_01007 6.23e-10 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLLFOCLF_01009 4.1e-219 - - - S - - - PglZ domain
CLLFOCLF_01010 2.85e-65 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
CLLFOCLF_01012 0.0 - - - LV - - - Eco57I restriction-modification methylase
CLLFOCLF_01013 8.16e-256 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
CLLFOCLF_01014 3.59e-64 - - - S - - - Domain of unknown function (DUF1788)
CLLFOCLF_01015 8.1e-57 - - - S - - - Putative inner membrane protein (DUF1819)
CLLFOCLF_01017 2.09e-130 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLLFOCLF_01018 3.01e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CLLFOCLF_01019 5.49e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLLFOCLF_01020 9.25e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLLFOCLF_01021 5.87e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLLFOCLF_01022 9.16e-209 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
CLLFOCLF_01023 1.47e-212 yitL - - S ko:K00243 - ko00000 S1 domain
CLLFOCLF_01024 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CLLFOCLF_01025 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CLLFOCLF_01026 3.79e-40 - - - S - - - Protein of unknown function (DUF2929)
CLLFOCLF_01027 2.61e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CLLFOCLF_01028 1.1e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLLFOCLF_01029 1.27e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CLLFOCLF_01030 7.19e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLLFOCLF_01031 1.03e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CLLFOCLF_01032 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CLLFOCLF_01033 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CLLFOCLF_01034 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CLLFOCLF_01035 1.02e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CLLFOCLF_01036 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLLFOCLF_01037 1.66e-77 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
CLLFOCLF_01038 2.21e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLLFOCLF_01039 2.22e-231 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
CLLFOCLF_01040 2.54e-219 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CLLFOCLF_01041 3.65e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
CLLFOCLF_01042 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
CLLFOCLF_01043 2.07e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
CLLFOCLF_01044 3.3e-121 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CLLFOCLF_01045 1.61e-92 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CLLFOCLF_01046 6.71e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
CLLFOCLF_01047 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CLLFOCLF_01048 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
CLLFOCLF_01049 2.57e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01050 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CLLFOCLF_01051 3.62e-212 - - - G - - - Phosphotransferase enzyme family
CLLFOCLF_01052 7.65e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CLLFOCLF_01053 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLLFOCLF_01054 1.94e-68 - - - - - - - -
CLLFOCLF_01055 1.08e-161 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CLLFOCLF_01056 1.89e-228 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
CLLFOCLF_01057 3.36e-77 - - - - - - - -
CLLFOCLF_01059 7.92e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CLLFOCLF_01061 1.74e-177 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
CLLFOCLF_01062 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CLLFOCLF_01063 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CLLFOCLF_01064 1.81e-272 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CLLFOCLF_01065 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CLLFOCLF_01066 3.69e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLLFOCLF_01067 7.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CLLFOCLF_01068 1.04e-83 - - - - - - - -
CLLFOCLF_01069 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CLLFOCLF_01070 1.52e-209 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLLFOCLF_01071 2.79e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLLFOCLF_01072 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLLFOCLF_01073 7.97e-65 ylxQ - - J - - - ribosomal protein
CLLFOCLF_01074 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
CLLFOCLF_01075 1.18e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CLLFOCLF_01076 6.36e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CLLFOCLF_01077 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLLFOCLF_01078 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CLLFOCLF_01079 3.85e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CLLFOCLF_01080 5.83e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CLLFOCLF_01081 1.29e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLLFOCLF_01082 3.48e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CLLFOCLF_01083 1.72e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CLLFOCLF_01084 1.82e-196 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLLFOCLF_01085 2.91e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CLLFOCLF_01086 1.62e-230 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLLFOCLF_01087 9.65e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
CLLFOCLF_01088 1.62e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
CLLFOCLF_01089 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
CLLFOCLF_01090 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
CLLFOCLF_01091 2.7e-47 ynzC - - S - - - UPF0291 protein
CLLFOCLF_01092 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLLFOCLF_01093 1.94e-268 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
CLLFOCLF_01094 7.21e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLLFOCLF_01099 1.03e-72 - - - - - - - -
CLLFOCLF_01101 1.78e-119 - - - S ko:K06919 - ko00000 D5 N terminal like
CLLFOCLF_01102 3.52e-63 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
CLLFOCLF_01107 1.2e-29 - - - S - - - Helix-turn-helix domain
CLLFOCLF_01108 2.96e-20 ansR - - K - - - Transcriptional regulator
CLLFOCLF_01109 4.29e-16 - - - M - - - LysM domain
CLLFOCLF_01110 5.58e-173 int2 - - L - - - Belongs to the 'phage' integrase family
CLLFOCLF_01111 2.18e-122 - - - - - - - -
CLLFOCLF_01112 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLLFOCLF_01113 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CLLFOCLF_01114 2.9e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLLFOCLF_01115 2.79e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CLLFOCLF_01116 2.8e-313 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLLFOCLF_01117 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CLLFOCLF_01118 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
CLLFOCLF_01119 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CLLFOCLF_01120 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLLFOCLF_01121 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CLLFOCLF_01122 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLLFOCLF_01123 3.07e-209 - - - S - - - Tetratricopeptide repeat
CLLFOCLF_01124 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLLFOCLF_01125 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLLFOCLF_01126 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CLLFOCLF_01127 2.27e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CLLFOCLF_01128 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CLLFOCLF_01129 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
CLLFOCLF_01130 4.83e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
CLLFOCLF_01131 2.03e-250 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CLLFOCLF_01132 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLLFOCLF_01133 6.53e-127 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
CLLFOCLF_01134 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
CLLFOCLF_01135 4.36e-283 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CLLFOCLF_01136 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CLLFOCLF_01137 2.28e-173 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
CLLFOCLF_01138 1.94e-61 yktA - - S - - - Belongs to the UPF0223 family
CLLFOCLF_01139 1.67e-249 - - - S - - - Helix-turn-helix domain
CLLFOCLF_01140 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
CLLFOCLF_01141 1.04e-69 - - - M - - - Lysin motif
CLLFOCLF_01142 1.55e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CLLFOCLF_01143 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CLLFOCLF_01144 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CLLFOCLF_01145 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CLLFOCLF_01146 2.61e-298 XK27_05225 - - S - - - Tetratricopeptide repeat protein
CLLFOCLF_01147 1.42e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CLLFOCLF_01148 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01149 1.41e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLLFOCLF_01150 1.95e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLLFOCLF_01151 5.85e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
CLLFOCLF_01152 1.83e-195 WQ51_01275 - - S - - - EDD domain protein, DegV family
CLLFOCLF_01153 2.09e-215 - - - E - - - lipolytic protein G-D-S-L family
CLLFOCLF_01154 1.16e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
CLLFOCLF_01155 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
CLLFOCLF_01156 5.96e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLLFOCLF_01157 5.63e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLLFOCLF_01158 1.85e-205 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
CLLFOCLF_01159 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLLFOCLF_01160 3.08e-209 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CLLFOCLF_01161 1.23e-135 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CLLFOCLF_01162 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLLFOCLF_01163 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLLFOCLF_01164 1.02e-103 - - - F - - - NUDIX domain
CLLFOCLF_01165 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
CLLFOCLF_01166 2.49e-87 - - - S - - - Belongs to the HesB IscA family
CLLFOCLF_01167 1.61e-35 - - - - - - - -
CLLFOCLF_01169 2.87e-112 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
CLLFOCLF_01170 3.7e-79 asp1 - - S - - - Asp23 family, cell envelope-related function
CLLFOCLF_01171 3.61e-34 - - - - - - - -
CLLFOCLF_01172 7.38e-121 - - - - - - - -
CLLFOCLF_01173 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CLLFOCLF_01174 2.66e-230 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
CLLFOCLF_01175 1.13e-252 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
CLLFOCLF_01176 4.71e-301 int - - L ko:K06400 - ko00000 COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLLFOCLF_01177 1.38e-53 - - - S - - - Domain of unknown function DUF1829
CLLFOCLF_01178 3.01e-46 - - - - - - - -
CLLFOCLF_01181 7.41e-65 - - - K - - - Helix-turn-helix XRE-family like proteins
CLLFOCLF_01182 1.54e-10 - - - - - - - -
CLLFOCLF_01183 9.58e-154 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
CLLFOCLF_01190 2.44e-55 - - - S - - - ERF superfamily
CLLFOCLF_01191 2.03e-107 - - - S - - - Putative HNHc nuclease
CLLFOCLF_01192 2.39e-30 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
CLLFOCLF_01193 5.46e-36 - - - L - - - DnaD domain protein
CLLFOCLF_01194 5.74e-44 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
CLLFOCLF_01198 3.37e-32 - - - S - - - Protein of unknown function (DUF1064)
CLLFOCLF_01201 2.82e-37 - - - - - - - -
CLLFOCLF_01208 5.14e-87 - - - K - - - Protein of unknown function (DUF4065)
CLLFOCLF_01209 6.15e-34 - - - - - - - -
CLLFOCLF_01210 1.15e-15 - - - - - - - -
CLLFOCLF_01213 8.04e-189 - - - L - - - HNH nucleases
CLLFOCLF_01214 2.81e-101 - - - L - - - Phage terminase, small subunit
CLLFOCLF_01215 0.0 terL - - S - - - overlaps another CDS with the same product name
CLLFOCLF_01217 1.31e-306 - - - S - - - Phage portal protein
CLLFOCLF_01218 1.18e-146 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
CLLFOCLF_01219 3.13e-202 - - - S - - - Phage capsid family
CLLFOCLF_01220 8.12e-90 - - - S - - - Phage gp6-like head-tail connector protein
CLLFOCLF_01221 2.61e-53 - - - S - - - Phage head-tail joining protein
CLLFOCLF_01222 7.55e-82 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLLFOCLF_01223 1.15e-99 - - - - - - - -
CLLFOCLF_01224 9.12e-147 - - - - - - - -
CLLFOCLF_01226 8.23e-28 - - - - - - - -
CLLFOCLF_01227 0.0 - - - L - - - Phage tail tape measure protein TP901
CLLFOCLF_01228 1.22e-173 - - - S - - - Phage tail protein
CLLFOCLF_01229 8.11e-276 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
CLLFOCLF_01231 3.34e-113 - - - S - - - Domain of unknown function (DUF2479)
CLLFOCLF_01235 1.06e-43 - - - - - - - -
CLLFOCLF_01236 1.15e-59 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
CLLFOCLF_01237 4.71e-194 - - - M - - - Glycosyl hydrolases family 25
CLLFOCLF_01238 1.05e-26 - - - - - - - -
CLLFOCLF_01239 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CLLFOCLF_01240 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
CLLFOCLF_01241 5.39e-28 - - - - - - - -
CLLFOCLF_01242 1.81e-41 - - - - - - - -
CLLFOCLF_01243 1.26e-60 - - - - - - - -
CLLFOCLF_01244 6.49e-104 - - - S - - - Protein of unknown function (DUF805)
CLLFOCLF_01245 8.37e-41 - - - LO ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
CLLFOCLF_01246 0.0 - - - L - - - PLD-like domain
CLLFOCLF_01257 1.74e-125 - - - K - - - Acetyltransferase (GNAT) domain
CLLFOCLF_01258 3.48e-203 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
CLLFOCLF_01259 7.58e-71 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
CLLFOCLF_01260 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
CLLFOCLF_01261 1.61e-143 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLLFOCLF_01262 7.79e-205 - - - O - - - Uncharacterized protein family (UPF0051)
CLLFOCLF_01263 5.35e-86 - - - M - - - LysM domain protein
CLLFOCLF_01264 0.0 - - - EP - - - Psort location Cytoplasmic, score
CLLFOCLF_01265 6.6e-131 - - - M - - - LysM domain protein
CLLFOCLF_01266 3.95e-126 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CLLFOCLF_01267 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CLLFOCLF_01268 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
CLLFOCLF_01269 3.69e-196 yeaE - - S - - - Aldo keto
CLLFOCLF_01270 3.81e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CLLFOCLF_01271 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
CLLFOCLF_01272 4.4e-101 - - - S - - - Psort location Cytoplasmic, score
CLLFOCLF_01273 1e-101 - - - S - - - Short repeat of unknown function (DUF308)
CLLFOCLF_01274 7.03e-33 - - - - - - - -
CLLFOCLF_01275 5.83e-135 - - - V - - - VanZ like family
CLLFOCLF_01276 2.01e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CLLFOCLF_01277 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
CLLFOCLF_01278 0.0 - - - EGP - - - Major Facilitator
CLLFOCLF_01279 7.72e-122 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
CLLFOCLF_01280 2.71e-280 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLLFOCLF_01281 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CLLFOCLF_01282 1.77e-56 - - - - - - - -
CLLFOCLF_01283 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
CLLFOCLF_01284 2.05e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLLFOCLF_01285 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
CLLFOCLF_01286 2.18e-112 - - - T - - - Belongs to the universal stress protein A family
CLLFOCLF_01287 2.83e-225 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLLFOCLF_01288 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
CLLFOCLF_01289 1.78e-145 - - - - - - - -
CLLFOCLF_01290 3.58e-238 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
CLLFOCLF_01291 8.09e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLLFOCLF_01292 1.78e-42 - - - - - - - -
CLLFOCLF_01293 4.46e-141 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
CLLFOCLF_01294 9.17e-59 - - - - - - - -
CLLFOCLF_01296 3.65e-90 - - - - - - - -
CLLFOCLF_01297 8.28e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLLFOCLF_01298 1.25e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CLLFOCLF_01299 1.94e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
CLLFOCLF_01300 1.06e-280 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CLLFOCLF_01301 4.06e-134 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
CLLFOCLF_01302 1.67e-270 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
CLLFOCLF_01303 1.88e-60 - - - - - - - -
CLLFOCLF_01304 2.47e-53 - - - - - - - -
CLLFOCLF_01306 3.72e-211 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CLLFOCLF_01307 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CLLFOCLF_01308 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CLLFOCLF_01309 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CLLFOCLF_01310 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
CLLFOCLF_01311 2.15e-281 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
CLLFOCLF_01312 0.0 yhaN - - L - - - AAA domain
CLLFOCLF_01313 4.08e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CLLFOCLF_01314 8.62e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
CLLFOCLF_01315 2.7e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01316 2.32e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CLLFOCLF_01317 6.19e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CLLFOCLF_01318 1.43e-38 - - - S - - - YSIRK type signal peptide
CLLFOCLF_01319 1.56e-13 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CLLFOCLF_01320 5.37e-74 - - - S - - - Small secreted protein
CLLFOCLF_01321 2.95e-75 ytpP - - CO - - - Thioredoxin
CLLFOCLF_01322 4.88e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLLFOCLF_01323 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CLLFOCLF_01324 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
CLLFOCLF_01325 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLLFOCLF_01326 5.3e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CLLFOCLF_01327 9.4e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLLFOCLF_01328 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLLFOCLF_01329 3.85e-298 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
CLLFOCLF_01330 8.6e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CLLFOCLF_01331 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLLFOCLF_01332 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CLLFOCLF_01333 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLLFOCLF_01334 6.39e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
CLLFOCLF_01335 2.21e-278 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
CLLFOCLF_01336 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
CLLFOCLF_01337 1.11e-154 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLLFOCLF_01338 1.64e-142 yqeK - - H - - - Hydrolase, HD family
CLLFOCLF_01339 1.9e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CLLFOCLF_01340 4.83e-174 yqeM - - Q - - - Methyltransferase
CLLFOCLF_01341 2.98e-268 ylbM - - S - - - Belongs to the UPF0348 family
CLLFOCLF_01342 2.89e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
CLLFOCLF_01343 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CLLFOCLF_01344 9.72e-156 csrR - - K - - - response regulator
CLLFOCLF_01345 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLLFOCLF_01346 0.0 potE - - E - - - Amino Acid
CLLFOCLF_01347 1.51e-297 - - - V - - - MatE
CLLFOCLF_01348 3.07e-89 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
CLLFOCLF_01349 3.89e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLLFOCLF_01350 4.22e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CLLFOCLF_01351 1.1e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLLFOCLF_01352 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CLLFOCLF_01353 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
CLLFOCLF_01354 6.06e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLLFOCLF_01355 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLLFOCLF_01356 9.83e-148 - - - M - - - PFAM NLP P60 protein
CLLFOCLF_01357 1.14e-149 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CLLFOCLF_01358 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLLFOCLF_01359 0.0 bamA - - GM ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 domain, Protein
CLLFOCLF_01360 0.0 - - - S - - - Peptidase, M23
CLLFOCLF_01361 0.0 - - - M - - - NlpC/P60 family
CLLFOCLF_01362 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLLFOCLF_01363 2.39e-301 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
CLLFOCLF_01364 3.74e-232 yueF - - S - - - AI-2E family transporter
CLLFOCLF_01365 8.28e-203 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
CLLFOCLF_01366 6.42e-200 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CLLFOCLF_01367 1.49e-87 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CLLFOCLF_01368 7.93e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CLLFOCLF_01369 1.58e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLLFOCLF_01370 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLLFOCLF_01371 2.46e-173 - - - - - - - -
CLLFOCLF_01372 4.52e-184 - - - M - - - Glycosyl transferase family 2
CLLFOCLF_01373 5.44e-96 - - - - - - - -
CLLFOCLF_01374 6.45e-89 - - - S - - - Acyltransferase family
CLLFOCLF_01375 4.99e-98 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
CLLFOCLF_01376 4.46e-84 - - - S - - - Glycosyltransferase like family
CLLFOCLF_01377 1.1e-95 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
CLLFOCLF_01378 9.63e-38 - - - M - - - biosynthesis protein
CLLFOCLF_01379 2.69e-109 - - - - - - - -
CLLFOCLF_01380 4.89e-94 - - - M - - - transferase activity, transferring glycosyl groups
CLLFOCLF_01381 2.42e-265 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
CLLFOCLF_01382 4.12e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
CLLFOCLF_01383 2.54e-45 - - - - - - - -
CLLFOCLF_01384 1.1e-199 - - - G - - - Peptidase_C39 like family
CLLFOCLF_01385 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
CLLFOCLF_01386 2.23e-150 - - - M - - - Bacterial sugar transferase
CLLFOCLF_01387 2.87e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
CLLFOCLF_01388 1.57e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
CLLFOCLF_01389 4.55e-172 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
CLLFOCLF_01390 2.53e-42 - - - - - - - -
CLLFOCLF_01391 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
CLLFOCLF_01392 5.01e-197 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CLLFOCLF_01393 0.0 potE - - E - - - Amino Acid
CLLFOCLF_01394 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
CLLFOCLF_01395 1.69e-281 arcT - - E - - - Aminotransferase
CLLFOCLF_01396 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
CLLFOCLF_01397 1.92e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
CLLFOCLF_01398 2.45e-88 gtcA - - S - - - Teichoic acid glycosylation protein
CLLFOCLF_01399 1.01e-26 - - - - - - - -
CLLFOCLF_01400 2.09e-266 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CLLFOCLF_01402 9.46e-298 yfmL - - L - - - DEAD DEAH box helicase
CLLFOCLF_01403 1.08e-244 mocA - - S - - - Oxidoreductase
CLLFOCLF_01404 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
CLLFOCLF_01405 1.46e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
CLLFOCLF_01406 2.16e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
CLLFOCLF_01407 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
CLLFOCLF_01408 1.36e-248 - - - S - - - Protein of unknown function (DUF3114)
CLLFOCLF_01409 1.85e-104 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
CLLFOCLF_01410 7.25e-150 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
CLLFOCLF_01411 1.46e-119 - - - K - - - Acetyltransferase (GNAT) family
CLLFOCLF_01412 2.03e-100 - - - K - - - LytTr DNA-binding domain
CLLFOCLF_01413 2.62e-89 - - - S - - - Protein of unknown function (DUF3021)
CLLFOCLF_01414 1e-217 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
CLLFOCLF_01415 2.07e-97 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
CLLFOCLF_01416 5.92e-38 pnb - - C - - - nitroreductase
CLLFOCLF_01417 8.49e-85 pnb - - C - - - nitroreductase
CLLFOCLF_01418 4.18e-119 - - - - - - - -
CLLFOCLF_01419 1.38e-108 yvbK - - K - - - GNAT family
CLLFOCLF_01420 1.76e-313 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
CLLFOCLF_01421 2.44e-266 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
CLLFOCLF_01422 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLLFOCLF_01423 7.62e-132 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
CLLFOCLF_01424 1.77e-237 - - - I - - - Alpha beta
CLLFOCLF_01425 0.0 qacA - - EGP - - - Major Facilitator
CLLFOCLF_01426 4.49e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
CLLFOCLF_01427 0.0 - - - S - - - Putative threonine/serine exporter
CLLFOCLF_01428 3.43e-203 - - - K - - - LysR family
CLLFOCLF_01429 3.08e-144 - - - I - - - Alpha/beta hydrolase family
CLLFOCLF_01430 3.34e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CLLFOCLF_01431 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
CLLFOCLF_01432 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
CLLFOCLF_01433 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
CLLFOCLF_01434 6.6e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLLFOCLF_01435 9.44e-223 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
CLLFOCLF_01436 9.08e-158 citR - - K - - - sugar-binding domain protein
CLLFOCLF_01437 2.64e-283 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CLLFOCLF_01438 1.52e-164 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CLLFOCLF_01439 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
CLLFOCLF_01440 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CLLFOCLF_01441 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
CLLFOCLF_01442 1.44e-202 mleR - - K - - - LysR family
CLLFOCLF_01443 6.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLLFOCLF_01444 3.17e-262 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
CLLFOCLF_01445 1.76e-286 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
CLLFOCLF_01446 3.46e-38 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
CLLFOCLF_01447 8.07e-07 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
CLLFOCLF_01448 3.68e-214 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
CLLFOCLF_01449 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
CLLFOCLF_01450 5.7e-30 - - - - - - - -
CLLFOCLF_01451 7.11e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
CLLFOCLF_01452 4.24e-94 - - - - - - - -
CLLFOCLF_01453 3.8e-292 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CLLFOCLF_01454 1.67e-179 - - - V - - - Beta-lactamase enzyme family
CLLFOCLF_01455 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
CLLFOCLF_01456 1.09e-275 - - - EGP - - - Transporter, major facilitator family protein
CLLFOCLF_01457 0.0 arcT - - E - - - Dipeptidase
CLLFOCLF_01458 1.69e-155 arcD - - S - - - C4-dicarboxylate anaerobic carrier
CLLFOCLF_01459 2.46e-172 isp - - L - - - Transposase
CLLFOCLF_01460 9.03e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
CLLFOCLF_01461 7.42e-118 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
CLLFOCLF_01462 1.96e-146 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
CLLFOCLF_01463 1.02e-171 - - - I - - - alpha/beta hydrolase fold
CLLFOCLF_01464 2.77e-228 - - - S - - - Conserved hypothetical protein 698
CLLFOCLF_01465 3.6e-109 - - - S - - - NADPH-dependent FMN reductase
CLLFOCLF_01466 1.13e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CLLFOCLF_01467 1.56e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
CLLFOCLF_01468 2.68e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CLLFOCLF_01469 1.12e-112 - - - Q - - - Methyltransferase
CLLFOCLF_01470 2.68e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
CLLFOCLF_01471 1.94e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
CLLFOCLF_01472 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
CLLFOCLF_01473 1.32e-295 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
CLLFOCLF_01474 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
CLLFOCLF_01475 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CLLFOCLF_01476 4.81e-293 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
CLLFOCLF_01477 2.49e-232 ampC - - V - - - Beta-lactamase
CLLFOCLF_01478 1.82e-69 - - - - - - - -
CLLFOCLF_01479 3.33e-177 isp - - L - - - Transposase
CLLFOCLF_01480 8.58e-192 - - - M - - - domain protein
CLLFOCLF_01481 0.0 - - - M - - - domain protein
CLLFOCLF_01482 2.84e-136 - - - - - - - -
CLLFOCLF_01484 1.05e-96 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
CLLFOCLF_01485 1.81e-188 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
CLLFOCLF_01486 1.5e-74 - - - - - - - -
CLLFOCLF_01488 6.11e-111 - - - - - - - -
CLLFOCLF_01489 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CLLFOCLF_01490 4.39e-71 - - - S - - - Cupredoxin-like domain
CLLFOCLF_01491 7.03e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
CLLFOCLF_01492 7.7e-202 - - - EG - - - EamA-like transporter family
CLLFOCLF_01493 3.94e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
CLLFOCLF_01494 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLLFOCLF_01495 1.06e-198 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
CLLFOCLF_01496 3.42e-41 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
CLLFOCLF_01498 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CLLFOCLF_01499 1.07e-138 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
CLLFOCLF_01500 2.14e-197 - - - U ko:K05340 - ko00000,ko02000 sugar transport
CLLFOCLF_01501 0.0 yclK - - T - - - Histidine kinase
CLLFOCLF_01502 2.81e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
CLLFOCLF_01504 6.22e-107 lytE - - M - - - Lysin motif
CLLFOCLF_01505 6.2e-103 - - - K - - - Transcriptional regulator
CLLFOCLF_01506 0.0 oatA - - I - - - Acyltransferase
CLLFOCLF_01507 3e-69 - - - - - - - -
CLLFOCLF_01508 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CLLFOCLF_01509 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLLFOCLF_01510 5.7e-165 ybbR - - S - - - YbbR-like protein
CLLFOCLF_01511 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLLFOCLF_01512 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
CLLFOCLF_01513 8.28e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CLLFOCLF_01514 5.49e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLLFOCLF_01515 3.22e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
CLLFOCLF_01516 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CLLFOCLF_01517 1.45e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
CLLFOCLF_01518 4.36e-114 - - - K - - - Acetyltransferase (GNAT) domain
CLLFOCLF_01519 9.26e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
CLLFOCLF_01520 1.14e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
CLLFOCLF_01521 4.35e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLLFOCLF_01522 3.91e-136 - - - - - - - -
CLLFOCLF_01523 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CLLFOCLF_01524 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CLLFOCLF_01525 1.5e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
CLLFOCLF_01526 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
CLLFOCLF_01527 0.0 eriC - - P ko:K03281 - ko00000 chloride
CLLFOCLF_01528 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
CLLFOCLF_01529 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CLLFOCLF_01530 1.45e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLLFOCLF_01531 1.04e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CLLFOCLF_01532 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CLLFOCLF_01534 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CLLFOCLF_01535 1.83e-21 - - - - - - - -
CLLFOCLF_01537 1.59e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CLLFOCLF_01538 9.5e-238 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CLLFOCLF_01539 7.72e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CLLFOCLF_01540 4.5e-315 steT - - E ko:K03294 - ko00000 amino acid
CLLFOCLF_01541 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CLLFOCLF_01542 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CLLFOCLF_01543 1.03e-19 - - - - - - - -
CLLFOCLF_01544 1.45e-149 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
CLLFOCLF_01545 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CLLFOCLF_01546 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
CLLFOCLF_01547 4.03e-206 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
CLLFOCLF_01548 1.06e-258 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
CLLFOCLF_01549 9.67e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CLLFOCLF_01550 1.12e-214 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
CLLFOCLF_01551 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
CLLFOCLF_01552 4.31e-176 lutC - - S ko:K00782 - ko00000 LUD domain
CLLFOCLF_01553 1.09e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CLLFOCLF_01554 9.42e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CLLFOCLF_01555 9.5e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLLFOCLF_01556 3.96e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLLFOCLF_01557 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
CLLFOCLF_01558 4.27e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
CLLFOCLF_01559 9.13e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLLFOCLF_01560 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CLLFOCLF_01561 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLLFOCLF_01562 4.08e-147 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
CLLFOCLF_01563 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
CLLFOCLF_01564 1.44e-139 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
CLLFOCLF_01565 5.95e-46 - - - EGP - - - Major Facilitator
CLLFOCLF_01566 2.35e-193 - - - EGP - - - Major Facilitator
CLLFOCLF_01567 2.53e-88 - - - K - - - Transcriptional regulator
CLLFOCLF_01568 1.53e-52 - - - - - - - -
CLLFOCLF_01569 0.0 ydaO - - E - - - amino acid
CLLFOCLF_01570 0.0 - - - E - - - amino acid
CLLFOCLF_01571 7.03e-103 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
CLLFOCLF_01572 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CLLFOCLF_01573 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLLFOCLF_01575 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLLFOCLF_01576 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
CLLFOCLF_01577 4.85e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLLFOCLF_01578 5.13e-288 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLLFOCLF_01579 7.09e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
CLLFOCLF_01580 1.48e-176 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLLFOCLF_01581 8.21e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLLFOCLF_01582 1.47e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLLFOCLF_01583 1.13e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLLFOCLF_01584 1.89e-129 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
CLLFOCLF_01585 2.56e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
CLLFOCLF_01586 2.35e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CLLFOCLF_01587 7.29e-219 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
CLLFOCLF_01588 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLLFOCLF_01589 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
CLLFOCLF_01590 4.11e-174 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
CLLFOCLF_01591 1.24e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLLFOCLF_01592 1.77e-74 yabA - - L - - - Involved in initiation control of chromosome replication
CLLFOCLF_01593 1.68e-231 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CLLFOCLF_01594 1.64e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
CLLFOCLF_01595 3.41e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLLFOCLF_01596 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
CLLFOCLF_01597 1.65e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLLFOCLF_01598 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLLFOCLF_01599 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLLFOCLF_01600 1.16e-114 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CLLFOCLF_01601 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
CLLFOCLF_01602 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLLFOCLF_01603 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLLFOCLF_01604 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
CLLFOCLF_01605 1.32e-169 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CLLFOCLF_01606 1.14e-128 - - - S - - - Protein of unknown function (DUF1700)
CLLFOCLF_01607 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
CLLFOCLF_01608 3.29e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CLLFOCLF_01610 8.34e-65 - - - - - - - -
CLLFOCLF_01611 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CLLFOCLF_01612 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLLFOCLF_01613 1.36e-212 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CLLFOCLF_01614 1.21e-284 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
CLLFOCLF_01615 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CLLFOCLF_01616 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLLFOCLF_01617 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CLLFOCLF_01618 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CLLFOCLF_01619 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CLLFOCLF_01620 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLLFOCLF_01621 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLLFOCLF_01622 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CLLFOCLF_01623 5.49e-262 yacL - - S - - - domain protein
CLLFOCLF_01624 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLLFOCLF_01625 8.07e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
CLLFOCLF_01626 4.04e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
CLLFOCLF_01627 2.92e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLLFOCLF_01628 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
CLLFOCLF_01629 3.37e-178 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
CLLFOCLF_01630 4.11e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01631 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLLFOCLF_01632 6.07e-274 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CLLFOCLF_01633 6.02e-214 - - - I - - - alpha/beta hydrolase fold
CLLFOCLF_01634 1.02e-170 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLLFOCLF_01635 0.0 - - - S - - - Bacterial membrane protein, YfhO
CLLFOCLF_01636 3.71e-235 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
CLLFOCLF_01637 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
CLLFOCLF_01639 1.78e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CLLFOCLF_01640 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
CLLFOCLF_01641 2.15e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CLLFOCLF_01642 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLLFOCLF_01643 2.05e-164 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
CLLFOCLF_01644 3.53e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CLLFOCLF_01645 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
CLLFOCLF_01646 3.57e-316 - - - EGP - - - Major Facilitator
CLLFOCLF_01647 1.09e-143 - - - - - - - -
CLLFOCLF_01650 4.13e-190 - - - S - - - Calcineurin-like phosphoesterase
CLLFOCLF_01651 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
CLLFOCLF_01654 1.59e-10 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLLFOCLF_01656 6.57e-151 - - - L - - - Integrase core domain
CLLFOCLF_01657 5e-142 - - - L - - - Bacterial dnaA protein
CLLFOCLF_01658 1.33e-174 - - - S - - - Alpha beta hydrolase
CLLFOCLF_01659 8.03e-277 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CLLFOCLF_01660 1.46e-126 - - - - - - - -
CLLFOCLF_01662 8.11e-159 - - - M - - - ErfK YbiS YcfS YnhG
CLLFOCLF_01663 0.0 - - - S - - - Putative peptidoglycan binding domain
CLLFOCLF_01664 2.05e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CLLFOCLF_01665 1.41e-88 - - - - - - - -
CLLFOCLF_01666 1.96e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CLLFOCLF_01667 6.08e-274 yttB - - EGP - - - Major Facilitator
CLLFOCLF_01668 4.7e-143 - - - - - - - -
CLLFOCLF_01669 2.6e-33 - - - - - - - -
CLLFOCLF_01670 1.8e-219 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
CLLFOCLF_01671 7.32e-317 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLLFOCLF_01672 8.23e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
CLLFOCLF_01673 1.61e-48 - - - - - - - -
CLLFOCLF_01674 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01675 1.37e-151 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01676 3.54e-220 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
CLLFOCLF_01677 8.43e-110 - - - K - - - transcriptional regulator (TetR family)
CLLFOCLF_01678 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
CLLFOCLF_01679 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CLLFOCLF_01680 2.57e-68 - - - - - - - -
CLLFOCLF_01681 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLLFOCLF_01683 6e-272 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
CLLFOCLF_01684 1.09e-63 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
CLLFOCLF_01685 6.99e-165 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
CLLFOCLF_01686 4.67e-313 - - - E ko:K03294 - ko00000 amino acid
CLLFOCLF_01687 9.04e-152 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLLFOCLF_01688 8.95e-20 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLLFOCLF_01689 4.09e-96 - - - S ko:K02348 - ko00000 Gnat family
CLLFOCLF_01690 1.11e-156 - - - GM - - - NmrA-like family
CLLFOCLF_01691 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
CLLFOCLF_01692 6.45e-138 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
CLLFOCLF_01693 1.25e-106 - - - K - - - Transcriptional regulator, HxlR family
CLLFOCLF_01694 1.24e-295 - - - - - - - -
CLLFOCLF_01695 2.18e-268 - - - EGP - - - Major Facilitator Superfamily
CLLFOCLF_01696 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
CLLFOCLF_01697 9.37e-142 - - - GM - - - NAD dependent epimerase dehydratase family protein
CLLFOCLF_01698 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
CLLFOCLF_01699 1.86e-63 ywnA - - K - - - Transcriptional regulator
CLLFOCLF_01700 1.64e-32 - - - S - - - ECF transporter, substrate-specific component
CLLFOCLF_01701 2.03e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
CLLFOCLF_01702 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
CLLFOCLF_01703 2.98e-33 - - - L - - - PFAM Integrase catalytic region
CLLFOCLF_01704 2.72e-164 - - - F - - - glutamine amidotransferase
CLLFOCLF_01705 6.31e-79 - - - - - - - -
CLLFOCLF_01706 1.65e-128 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
CLLFOCLF_01707 8.78e-194 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
CLLFOCLF_01708 3.33e-187 - - - K - - - Transcriptional regulator
CLLFOCLF_01709 4.01e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
CLLFOCLF_01710 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
CLLFOCLF_01711 1.65e-219 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
CLLFOCLF_01712 6.93e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
CLLFOCLF_01713 8.21e-153 - - - S - - - Alpha beta hydrolase
CLLFOCLF_01714 1.02e-82 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
CLLFOCLF_01715 5.01e-104 - - - S - - - Peptidase propeptide and YPEB domain
CLLFOCLF_01716 1.15e-271 - - - T - - - GHKL domain
CLLFOCLF_01717 4e-141 - - - T - - - Transcriptional regulatory protein, C terminal
CLLFOCLF_01718 2.76e-23 - - - H - - - RibD C-terminal domain
CLLFOCLF_01720 1.17e-246 flp - - V - - - Beta-lactamase
CLLFOCLF_01721 2.49e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
CLLFOCLF_01722 8.66e-134 - - - S ko:K07507 - ko00000,ko02000 MgtC family
CLLFOCLF_01723 3.53e-18 - - - S - - - GyrI-like small molecule binding domain
CLLFOCLF_01725 5.14e-145 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CLLFOCLF_01726 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
CLLFOCLF_01727 7.24e-76 azlC - - E - - - azaleucine resistance protein AzlC
CLLFOCLF_01728 2.73e-111 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
CLLFOCLF_01729 2.58e-62 azlC - - E - - - azaleucine resistance protein AzlC
CLLFOCLF_01730 0.0 - - - K - - - Aminotransferase class I and II
CLLFOCLF_01731 9.57e-34 - - - S - - - amidohydrolase
CLLFOCLF_01732 1.15e-62 - - - S - - - amidohydrolase
CLLFOCLF_01733 1.42e-117 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
CLLFOCLF_01734 3.47e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CLLFOCLF_01735 4.26e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
CLLFOCLF_01736 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLLFOCLF_01737 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CLLFOCLF_01738 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CLLFOCLF_01739 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLLFOCLF_01740 8.52e-168 jag - - S ko:K06346 - ko00000 R3H domain protein
CLLFOCLF_01741 1.21e-171 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLLFOCLF_01742 5.68e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CLLFOCLF_01743 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
CLLFOCLF_01744 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLLFOCLF_01745 2.23e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CLLFOCLF_01746 1.09e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
CLLFOCLF_01747 9.43e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLLFOCLF_01748 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLLFOCLF_01749 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLLFOCLF_01750 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CLLFOCLF_01751 1.2e-113 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CLLFOCLF_01752 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLLFOCLF_01753 1.7e-95 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLLFOCLF_01754 1.73e-128 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
CLLFOCLF_01755 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CLLFOCLF_01756 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
CLLFOCLF_01757 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CLLFOCLF_01758 9.25e-270 yttB - - EGP - - - Major Facilitator
CLLFOCLF_01759 7.71e-81 - - - - - - - -
CLLFOCLF_01760 1.46e-207 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
CLLFOCLF_01762 5.01e-123 - - - S - - - Fic/DOC family
CLLFOCLF_01764 5.18e-94 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
CLLFOCLF_01765 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
CLLFOCLF_01767 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CLLFOCLF_01768 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLLFOCLF_01769 1.89e-312 yycH - - S - - - YycH protein
CLLFOCLF_01770 4.13e-192 yycI - - S - - - YycH protein
CLLFOCLF_01771 1.46e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
CLLFOCLF_01772 3.43e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
CLLFOCLF_01773 1.04e-110 pgpA - - I - - - Phosphatidylglycerophosphatase A
CLLFOCLF_01774 4.64e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
CLLFOCLF_01775 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLLFOCLF_01777 1.56e-125 - - - S - - - reductase
CLLFOCLF_01778 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
CLLFOCLF_01779 6.86e-98 - - - O - - - OsmC-like protein
CLLFOCLF_01780 4.23e-222 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLLFOCLF_01781 2.28e-272 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLLFOCLF_01782 2.49e-43 - - - - - - - -
CLLFOCLF_01783 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
CLLFOCLF_01785 1.86e-134 - - - K - - - PFAM GCN5-related N-acetyltransferase
CLLFOCLF_01786 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLLFOCLF_01787 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CLLFOCLF_01788 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CLLFOCLF_01789 3e-221 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
CLLFOCLF_01790 2.2e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CLLFOCLF_01791 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
CLLFOCLF_01792 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
CLLFOCLF_01793 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
CLLFOCLF_01794 5.97e-92 - - - - - - - -
CLLFOCLF_01795 1.02e-111 - - - T - - - Region found in RelA / SpoT proteins
CLLFOCLF_01796 3.15e-153 dltr - - K - - - response regulator
CLLFOCLF_01797 7.94e-290 sptS - - T - - - Histidine kinase
CLLFOCLF_01798 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
CLLFOCLF_01799 6.13e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
CLLFOCLF_01800 1.8e-215 - - - C - - - Aldo keto reductase
CLLFOCLF_01801 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
CLLFOCLF_01802 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
CLLFOCLF_01803 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
CLLFOCLF_01804 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CLLFOCLF_01805 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLLFOCLF_01806 5.46e-118 - - - - - - - -
CLLFOCLF_01807 4.65e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLLFOCLF_01809 8.95e-18 - - - E - - - amino acid
CLLFOCLF_01810 2.53e-17 - - - K - - - Transcriptional regulator, TetR family
CLLFOCLF_01811 2.18e-94 - - - K - - - Transcriptional regulator, TetR family
CLLFOCLF_01812 3.48e-94 - - - - - - - -
CLLFOCLF_01813 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CLLFOCLF_01814 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
CLLFOCLF_01815 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
CLLFOCLF_01816 7.98e-157 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
CLLFOCLF_01817 3.84e-235 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
CLLFOCLF_01818 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
CLLFOCLF_01819 9.89e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CLLFOCLF_01820 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
CLLFOCLF_01821 8.18e-224 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
CLLFOCLF_01822 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLLFOCLF_01824 1.41e-130 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
CLLFOCLF_01825 1.12e-269 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
CLLFOCLF_01826 2.3e-224 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CLLFOCLF_01827 1.73e-52 - - - L - - - Transposase
CLLFOCLF_01828 5.73e-316 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLLFOCLF_01829 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLLFOCLF_01830 8.05e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01831 1.24e-285 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
CLLFOCLF_01832 2.4e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
CLLFOCLF_01833 8.26e-219 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
CLLFOCLF_01834 6.22e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
CLLFOCLF_01835 1.36e-157 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
CLLFOCLF_01836 3.79e-193 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CLLFOCLF_01837 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
CLLFOCLF_01838 1.38e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CLLFOCLF_01839 2.37e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
CLLFOCLF_01840 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CLLFOCLF_01841 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
CLLFOCLF_01842 3.97e-153 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLLFOCLF_01843 4.64e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLLFOCLF_01844 6.43e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
CLLFOCLF_01845 5.43e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
CLLFOCLF_01846 6.79e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
CLLFOCLF_01847 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CLLFOCLF_01848 9.76e-161 vanR - - K - - - response regulator
CLLFOCLF_01849 3.73e-264 hpk31 - - T - - - Histidine kinase
CLLFOCLF_01850 8.37e-187 - - - E - - - AzlC protein
CLLFOCLF_01851 4.05e-70 - - - S - - - branched-chain amino acid
CLLFOCLF_01852 6.08e-177 - - - K - - - LysR substrate binding domain
CLLFOCLF_01853 1.48e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CLLFOCLF_01854 2.13e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CLLFOCLF_01855 3.93e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CLLFOCLF_01856 4.61e-166 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CLLFOCLF_01857 1.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLLFOCLF_01858 2.14e-147 - - - S - - - Haloacid dehalogenase-like hydrolase
CLLFOCLF_01859 2.62e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLLFOCLF_01860 1.35e-290 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
CLLFOCLF_01861 3.86e-223 ydbI - - K - - - AI-2E family transporter
CLLFOCLF_01862 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
CLLFOCLF_01863 8.15e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
CLLFOCLF_01864 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CLLFOCLF_01865 5.71e-53 - - - - - - - -
CLLFOCLF_01866 4.52e-160 pgm3 - - G - - - phosphoglycerate mutase family
CLLFOCLF_01867 1.51e-44 - - - K - - - Bacterial transcriptional regulator
CLLFOCLF_01869 5.78e-58 - - - IQ - - - dehydrogenase reductase
CLLFOCLF_01870 2.93e-202 - - - S - - - C4-dicarboxylate anaerobic carrier
CLLFOCLF_01871 1.89e-127 - - - S - - - C4-dicarboxylate anaerobic carrier
CLLFOCLF_01872 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
CLLFOCLF_01873 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CLLFOCLF_01874 3.34e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
CLLFOCLF_01875 3.46e-213 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CLLFOCLF_01876 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
CLLFOCLF_01877 1.3e-73 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CLLFOCLF_01878 1.2e-299 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
CLLFOCLF_01879 2.21e-72 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
CLLFOCLF_01880 2.98e-123 - - - P - - - Cadmium resistance transporter
CLLFOCLF_01881 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01882 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CLLFOCLF_01883 7.44e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
CLLFOCLF_01884 1.46e-156 - - - M - - - PFAM NLP P60 protein
CLLFOCLF_01885 2.96e-125 - - - S - - - Protein of unknown function (DUF3278)
CLLFOCLF_01886 5.78e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
CLLFOCLF_01887 2.18e-66 - - - L - - - Integrase
CLLFOCLF_01888 2.7e-18 XK27_09155 - - K - - - Transcriptional
CLLFOCLF_01889 1.31e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLLFOCLF_01890 1.78e-232 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
CLLFOCLF_01892 0.0 - - - S - - - ABC transporter, ATP-binding protein
CLLFOCLF_01893 8.04e-184 - - - S - - - Putative ABC-transporter type IV
CLLFOCLF_01894 2.85e-135 - - - NU - - - mannosyl-glycoprotein
CLLFOCLF_01895 5.41e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CLLFOCLF_01896 2.88e-290 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
CLLFOCLF_01897 1.84e-262 yngD - - S ko:K07097 - ko00000 DHHA1 domain
CLLFOCLF_01898 1.68e-64 - - - - - - - -
CLLFOCLF_01899 4.78e-39 - - - S - - - PD-(D/E)XK nuclease family transposase
CLLFOCLF_01901 9.17e-70 - - - - - - - -
CLLFOCLF_01902 1.43e-152 yrkL - - S - - - Flavodoxin-like fold
CLLFOCLF_01904 2.01e-84 yeaO - - S - - - Protein of unknown function, DUF488
CLLFOCLF_01905 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
CLLFOCLF_01906 1.2e-260 - - - S - - - associated with various cellular activities
CLLFOCLF_01907 5.41e-293 - - - S - - - Putative metallopeptidase domain
CLLFOCLF_01908 2.02e-62 - - - - - - - -
CLLFOCLF_01909 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
CLLFOCLF_01910 1.51e-137 - - - K - - - Helix-turn-helix XRE-family like proteins
CLLFOCLF_01911 2.1e-113 ymdB - - S - - - Macro domain protein
CLLFOCLF_01912 1.35e-248 - - - EGP - - - Major Facilitator
CLLFOCLF_01913 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLLFOCLF_01914 4.22e-69 - - - K - - - helix_turn_helix, mercury resistance
CLLFOCLF_01915 7.55e-213 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CLLFOCLF_01916 1.64e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
CLLFOCLF_01917 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
CLLFOCLF_01918 2.04e-173 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_01919 1.29e-234 kinG - - T - - - Histidine kinase-like ATPases
CLLFOCLF_01920 2.7e-172 XK27_10500 - - K - - - response regulator
CLLFOCLF_01921 8.44e-201 yvgN - - S - - - Aldo keto reductase
CLLFOCLF_01922 2.68e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
CLLFOCLF_01923 2.63e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLLFOCLF_01924 4.14e-257 - - - - - - - -
CLLFOCLF_01925 1.76e-68 - - - - - - - -
CLLFOCLF_01926 1.21e-48 - - - - - - - -
CLLFOCLF_01927 9.21e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
CLLFOCLF_01928 4.49e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
CLLFOCLF_01929 2.69e-227 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
CLLFOCLF_01930 4.92e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLLFOCLF_01931 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CLLFOCLF_01932 1.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CLLFOCLF_01933 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLLFOCLF_01934 2.7e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
CLLFOCLF_01935 2.71e-103 usp5 - - T - - - universal stress protein
CLLFOCLF_01936 2.65e-56 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CLLFOCLF_01937 1.62e-81 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
CLLFOCLF_01938 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
CLLFOCLF_01939 4.67e-39 - - - - - - - -
CLLFOCLF_01940 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLLFOCLF_01941 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLLFOCLF_01942 7.93e-242 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
CLLFOCLF_01943 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
CLLFOCLF_01944 3.16e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
CLLFOCLF_01945 6.23e-303 yhdP - - S - - - Transporter associated domain
CLLFOCLF_01946 1.14e-197 - - - V - - - (ABC) transporter
CLLFOCLF_01947 9.43e-116 - - - GM - - - epimerase
CLLFOCLF_01948 5.04e-116 - - - K - - - Domain of unknown function (DUF1836)
CLLFOCLF_01949 8.16e-103 yybA - - K - - - Transcriptional regulator
CLLFOCLF_01950 3.53e-169 XK27_07210 - - S - - - B3 4 domain
CLLFOCLF_01951 4.09e-235 XK27_12525 - - S - - - AI-2E family transporter
CLLFOCLF_01952 8.07e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
CLLFOCLF_01953 8.24e-205 - - - - - - - -
CLLFOCLF_01954 9.82e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CLLFOCLF_01955 4.02e-177 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
CLLFOCLF_01956 1.69e-202 - - - K - - - helix_turn_helix, arabinose operon control protein
CLLFOCLF_01957 2.33e-50 - - - CQ - - - BMC
CLLFOCLF_01958 3.41e-170 pduB - - E - - - BMC
CLLFOCLF_01959 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
CLLFOCLF_01960 5e-162 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
CLLFOCLF_01961 8.85e-97 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
CLLFOCLF_01962 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
CLLFOCLF_01963 4.57e-60 pduH - - S - - - Dehydratase medium subunit
CLLFOCLF_01964 2.67e-74 - - - CQ - - - BMC
CLLFOCLF_01965 3.65e-53 pduA_2 - - CQ ko:K04027 - ko00000 BMC
CLLFOCLF_01966 1.98e-148 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
CLLFOCLF_01967 1.25e-103 - - - S - - - Putative propanediol utilisation
CLLFOCLF_01968 5.63e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
CLLFOCLF_01969 2.85e-134 - - - S - - - Cobalamin adenosyltransferase
CLLFOCLF_01970 1.62e-101 pduO - - S - - - Haem-degrading
CLLFOCLF_01971 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
CLLFOCLF_01972 2.5e-258 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
CLLFOCLF_01973 2.06e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLLFOCLF_01974 5.3e-71 - - - E ko:K04031 - ko00000 BMC
CLLFOCLF_01975 1.08e-147 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
CLLFOCLF_01976 1.06e-96 pgm1 - - G - - - phosphoglycerate mutase
CLLFOCLF_01977 3.45e-87 - - - P - - - Cadmium resistance transporter
CLLFOCLF_01978 1.44e-90 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
CLLFOCLF_01979 4.54e-95 ykuP - - C ko:K03839 - ko00000 Flavodoxin
CLLFOCLF_01980 1.21e-147 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
CLLFOCLF_01981 1.72e-102 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
CLLFOCLF_01982 2.83e-215 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
CLLFOCLF_01983 2.22e-256 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
CLLFOCLF_01984 4.35e-186 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CLLFOCLF_01985 5.48e-139 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
CLLFOCLF_01986 1.39e-244 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CLLFOCLF_01987 6.19e-102 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
CLLFOCLF_01988 7.05e-100 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
CLLFOCLF_01989 5.75e-165 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
CLLFOCLF_01990 3.13e-181 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
CLLFOCLF_01991 2.29e-165 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
CLLFOCLF_01992 1.51e-125 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
CLLFOCLF_01993 3.44e-223 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
CLLFOCLF_01994 1.97e-138 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
CLLFOCLF_01995 5.52e-117 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
CLLFOCLF_01996 6.68e-159 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CLLFOCLF_01997 8.36e-59 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CLLFOCLF_01998 1.88e-131 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CLLFOCLF_01999 7.19e-155 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
CLLFOCLF_02000 3.39e-303 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
CLLFOCLF_02001 4.7e-76 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
CLLFOCLF_02002 6.66e-246 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLLFOCLF_02003 6.56e-174 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CLLFOCLF_02004 9.66e-224 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
CLLFOCLF_02005 9.62e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
CLLFOCLF_02006 1.41e-98 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
CLLFOCLF_02007 7.33e-152 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLLFOCLF_02008 4.47e-95 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
CLLFOCLF_02009 1.1e-91 - - - H - - - Uroporphyrinogen-III synthase
CLLFOCLF_02010 3.2e-185 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
CLLFOCLF_02011 1.31e-13 - - - EG - - - of the drug metabolite transporter (DMT) superfamily
CLLFOCLF_02012 1.4e-21 - - - EG - - - PFAM EamA-like transporter family
CLLFOCLF_02013 4.28e-66 - - - S - - - Domain of unknown function (DUF4430)
CLLFOCLF_02014 4.06e-103 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
CLLFOCLF_02015 2.8e-23 - - - S - - - PFAM Archaeal ATPase
CLLFOCLF_02017 2.17e-226 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLLFOCLF_02018 1.64e-23 - - - K - - - Winged helix-turn-helix DNA-binding
CLLFOCLF_02019 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_02020 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
CLLFOCLF_02021 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
CLLFOCLF_02022 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
CLLFOCLF_02023 1.85e-110 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLLFOCLF_02024 8.56e-162 gntR - - K - - - UbiC transcription regulator-associated domain protein
CLLFOCLF_02025 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
CLLFOCLF_02026 8.46e-301 - - - E - - - amino acid
CLLFOCLF_02027 7.15e-177 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
CLLFOCLF_02028 2.96e-211 - - - GK - - - ROK family
CLLFOCLF_02029 0.0 fusA1 - - J - - - elongation factor G
CLLFOCLF_02030 7.46e-106 uspA3 - - T - - - universal stress protein
CLLFOCLF_02031 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
CLLFOCLF_02032 1.78e-83 - - - - - - - -
CLLFOCLF_02033 2.31e-11 - - - - - - - -
CLLFOCLF_02034 5.95e-76 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
CLLFOCLF_02035 3.49e-50 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
CLLFOCLF_02036 3.74e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CLLFOCLF_02037 1.6e-269 - - - EGP - - - Major Facilitator
CLLFOCLF_02038 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
CLLFOCLF_02039 6.49e-30 - - - C - - - Zinc-binding dehydrogenase
CLLFOCLF_02040 1.4e-108 - - - C - - - Zinc-binding dehydrogenase
CLLFOCLF_02041 1.92e-204 - - - - - - - -
CLLFOCLF_02042 1.3e-95 - - - K - - - Transcriptional regulator
CLLFOCLF_02043 4.14e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
CLLFOCLF_02044 2.59e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
CLLFOCLF_02045 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
CLLFOCLF_02046 6.5e-71 - - - - - - - -
CLLFOCLF_02047 4.63e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CLLFOCLF_02048 7.23e-316 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLLFOCLF_02049 3e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
CLLFOCLF_02050 5.98e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
CLLFOCLF_02052 9e-144 - - - IQ - - - KR domain
CLLFOCLF_02053 5.68e-12 - - - IQ - - - KR domain
CLLFOCLF_02054 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
CLLFOCLF_02055 3.99e-232 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CLLFOCLF_02056 3.5e-43 - - - S - - - Double zinc ribbon
CLLFOCLF_02057 6.89e-75 - - - S - - - Double zinc ribbon
CLLFOCLF_02058 1.69e-44 - - - S - - - PD-(D/E)XK nuclease family transposase
CLLFOCLF_02059 2.16e-121 - - - S - - - PD-(D/E)XK nuclease family transposase
CLLFOCLF_02060 2.14e-148 - - - S - - - HAD hydrolase, family IA, variant
CLLFOCLF_02061 1.34e-223 yagE - - E - - - amino acid
CLLFOCLF_02062 4.5e-55 yagE - - E - - - amino acid
CLLFOCLF_02063 1.7e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CLLFOCLF_02064 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
CLLFOCLF_02065 6.09e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
CLLFOCLF_02066 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CLLFOCLF_02067 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CLLFOCLF_02068 4.13e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_02069 7.65e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
CLLFOCLF_02070 2.33e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLLFOCLF_02071 4.88e-42 - - - - - - - -
CLLFOCLF_02072 5.07e-82 - - - - - - - -
CLLFOCLF_02073 4.81e-22 - - - - - - - -
CLLFOCLF_02074 8e-39 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)