ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KLABLALB_00001 6.51e-45 - - - L - - - Psort location Cytoplasmic, score
KLABLALB_00002 1.25e-25 - - - L - - - Protein of unknown function (DUF3991)
KLABLALB_00003 2.09e-201 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
KLABLALB_00006 6.99e-181 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KLABLALB_00010 8.73e-264 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
KLABLALB_00011 4.29e-87 - - - - - - - -
KLABLALB_00014 4.83e-237 - - - U - - - type IV secretory pathway VirB4
KLABLALB_00016 1.38e-36 - - - M - - - CHAP domain
KLABLALB_00021 1.91e-49 - - - L - - - Belongs to the 'phage' integrase family
KLABLALB_00022 1.42e-34 - - - - - - - -
KLABLALB_00023 5e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KLABLALB_00024 1.15e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLABLALB_00025 8.46e-101 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_00026 1.94e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KLABLALB_00027 6.11e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KLABLALB_00028 2.37e-97 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
KLABLALB_00029 2.12e-48 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KLABLALB_00030 1.06e-13 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KLABLALB_00031 3.79e-113 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KLABLALB_00034 2.79e-157 - - - L - - - the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
KLABLALB_00035 0.0 - - - M - - - domain, Protein
KLABLALB_00036 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KLABLALB_00037 9.14e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KLABLALB_00038 3.94e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
KLABLALB_00039 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00040 2.84e-240 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KLABLALB_00041 1.07e-267 potE - - E - - - Amino Acid
KLABLALB_00042 2.51e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
KLABLALB_00043 1.78e-171 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
KLABLALB_00044 6.25e-77 - - - S - - - Glycosyltransferase like family 2
KLABLALB_00045 2.52e-140 cps3J - - M - - - Domain of unknown function (DUF4422)
KLABLALB_00046 1.39e-18 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
KLABLALB_00047 2.7e-50 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
KLABLALB_00048 4.86e-115 - - - M - - - Core-2/I-Branching enzyme
KLABLALB_00049 9.91e-47 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLABLALB_00050 2.58e-85 - - - D - - - Peptidase family M23
KLABLALB_00051 4.44e-85 lutC - - S ko:K00782 - ko00000 LUD domain
KLABLALB_00052 4.06e-310 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
KLABLALB_00053 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
KLABLALB_00054 3.78e-129 - - - E ko:K03294 - ko00000 Amino Acid
KLABLALB_00055 2.9e-121 - - - E ko:K03294 - ko00000 Amino Acid
KLABLALB_00057 3.61e-79 uspA3 - - T - - - universal stress protein
KLABLALB_00059 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
KLABLALB_00060 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLABLALB_00061 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KLABLALB_00062 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLABLALB_00063 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLABLALB_00064 1.41e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLABLALB_00065 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLABLALB_00066 3.58e-255 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KLABLALB_00067 1.06e-202 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLABLALB_00068 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLABLALB_00069 1.06e-84 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
KLABLALB_00070 7.38e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KLABLALB_00071 7.43e-22 ymfH - - S - - - Peptidase M16
KLABLALB_00072 1.61e-154 ymfH - - S - - - Peptidase M16
KLABLALB_00073 7.37e-137 ymfF - - S - - - Peptidase M16 inactive domain protein
KLABLALB_00074 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KLABLALB_00075 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLABLALB_00076 5e-125 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
KLABLALB_00077 1.44e-83 - - - J ko:K03976 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
KLABLALB_00078 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLABLALB_00079 3.47e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLABLALB_00080 2.07e-52 - - - K - - - Transcriptional regulator
KLABLALB_00081 8.36e-148 - - - S - - - EDD domain protein, DegV family
KLABLALB_00082 6.76e-92 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
KLABLALB_00083 2.4e-53 - - - S - - - ASCH
KLABLALB_00084 1.85e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLABLALB_00085 2.87e-98 - - - S - - - Calcineurin-like phosphoesterase
KLABLALB_00086 2.08e-121 - - - EG - - - EamA-like transporter family
KLABLALB_00087 3.32e-105 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
KLABLALB_00088 9.85e-142 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
KLABLALB_00089 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
KLABLALB_00090 2.12e-87 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLABLALB_00091 2.66e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
KLABLALB_00092 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KLABLALB_00093 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KLABLALB_00094 3.12e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLABLALB_00095 1.26e-235 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLABLALB_00097 2.23e-109 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLABLALB_00098 5.36e-51 - - - - - - - -
KLABLALB_00099 2.97e-149 icaA - - M - - - Glycosyl transferase family group 2
KLABLALB_00100 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
KLABLALB_00103 3.86e-14 - - - S - - - Bacteriophage holin
KLABLALB_00107 6.11e-79 - - - S - - - Protein of unknown function (DUF1211)
KLABLALB_00108 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLABLALB_00109 2.17e-140 ampC - - V - - - Beta-lactamase
KLABLALB_00110 1.83e-41 - - - - - - - -
KLABLALB_00111 1.5e-152 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00112 7.05e-257 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KLABLALB_00114 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLABLALB_00115 1.47e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
KLABLALB_00116 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
KLABLALB_00117 8.2e-10 - - - S - - - Putative adhesin
KLABLALB_00118 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KLABLALB_00121 4.13e-296 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLABLALB_00122 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
KLABLALB_00123 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KLABLALB_00124 3.25e-113 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
KLABLALB_00126 1.71e-44 - - - - - - - -
KLABLALB_00127 5.66e-246 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KLABLALB_00128 6.11e-158 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KLABLALB_00129 5.53e-61 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KLABLALB_00130 6.66e-76 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KLABLALB_00131 8.5e-24 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
KLABLALB_00132 1.61e-165 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KLABLALB_00133 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KLABLALB_00134 2.06e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLABLALB_00135 2.27e-87 ybbR - - S - - - YbbR-like protein
KLABLALB_00136 4.8e-163 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLABLALB_00137 5.56e-92 - - - S - - - Protein of unknown function (DUF1361)
KLABLALB_00138 3.49e-145 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KLABLALB_00139 2.74e-89 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KLABLALB_00140 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KLABLALB_00141 5.74e-180 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KLABLALB_00142 1.07e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLABLALB_00143 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
KLABLALB_00144 1.94e-53 - - - - - - - -
KLABLALB_00145 1.75e-90 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLABLALB_00146 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLABLALB_00147 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KLABLALB_00148 3.14e-224 eriC - - P ko:K03281 - ko00000 chloride
KLABLALB_00149 7.65e-189 - - - E - - - Major Facilitator Superfamily
KLABLALB_00150 4.69e-212 yclK - - T - - - Histidine kinase
KLABLALB_00151 2.54e-106 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
KLABLALB_00152 2.02e-167 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLABLALB_00153 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLABLALB_00154 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLABLALB_00155 1.15e-263 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KLABLALB_00156 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLABLALB_00157 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
KLABLALB_00159 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLABLALB_00160 5.14e-188 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KLABLALB_00161 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KLABLALB_00162 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KLABLALB_00163 7.97e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
KLABLALB_00164 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLABLALB_00165 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLABLALB_00166 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLABLALB_00167 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KLABLALB_00168 3.37e-142 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLABLALB_00169 8.3e-168 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLABLALB_00170 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KLABLALB_00171 1.44e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
KLABLALB_00172 7.33e-95 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KLABLALB_00174 5.4e-101 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KLABLALB_00175 7e-81 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
KLABLALB_00176 1.85e-206 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLABLALB_00177 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLABLALB_00178 3.91e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
KLABLALB_00179 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLABLALB_00180 7.98e-69 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KLABLALB_00181 1.23e-158 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KLABLALB_00182 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KLABLALB_00183 8.59e-21 - - - - - - - -
KLABLALB_00187 8.1e-110 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLABLALB_00188 3.38e-89 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KLABLALB_00189 3.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
KLABLALB_00190 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLABLALB_00191 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLABLALB_00192 3.4e-100 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLABLALB_00193 7.15e-57 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLABLALB_00194 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KLABLALB_00195 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLABLALB_00196 5.6e-17 - - - - - - - -
KLABLALB_00197 1.76e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
KLABLALB_00198 5.19e-56 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
KLABLALB_00199 1.12e-136 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KLABLALB_00200 1.01e-95 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLABLALB_00201 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLABLALB_00202 2.53e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLABLALB_00203 2.55e-72 yjcF - - J - - - HAD-hyrolase-like
KLABLALB_00204 7.34e-54 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLABLALB_00205 1.69e-164 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KLABLALB_00206 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLABLALB_00207 7.51e-257 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KLABLALB_00208 1.29e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KLABLALB_00209 1.95e-235 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KLABLALB_00210 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLABLALB_00211 1.05e-114 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLABLALB_00212 2.6e-172 - - - K - - - Transcriptional regulator
KLABLALB_00213 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KLABLALB_00214 4.04e-148 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KLABLALB_00215 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KLABLALB_00216 4.96e-111 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KLABLALB_00218 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLABLALB_00219 3.81e-218 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KLABLALB_00220 8.9e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
KLABLALB_00221 2.93e-34 - - - S - - - Family of unknown function (DUF5322)
KLABLALB_00222 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KLABLALB_00223 7.12e-50 - - - - - - - -
KLABLALB_00227 1.06e-19 - - - D - - - LPXTG cell wall anchor motif
KLABLALB_00229 2.37e-184 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KLABLALB_00230 9.72e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KLABLALB_00231 9.44e-131 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLABLALB_00232 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KLABLALB_00233 2.1e-30 alkD - - L - - - DNA alkylation repair enzyme
KLABLALB_00234 5.44e-39 alkD - - L - - - Dna alkylation repair
KLABLALB_00235 1.72e-174 - - - EG - - - EamA-like transporter family
KLABLALB_00236 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KLABLALB_00237 1.56e-256 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KLABLALB_00238 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLABLALB_00239 8.84e-167 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KLABLALB_00240 1.34e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KLABLALB_00241 2e-164 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLABLALB_00242 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KLABLALB_00244 1.42e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLABLALB_00245 1.65e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KLABLALB_00246 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
KLABLALB_00247 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLABLALB_00248 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLABLALB_00249 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
KLABLALB_00250 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KLABLALB_00251 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KLABLALB_00252 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KLABLALB_00253 7.38e-47 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
KLABLALB_00254 1.07e-113 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KLABLALB_00255 1.03e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
KLABLALB_00256 3.16e-192 - - - EGP - - - Major Facilitator
KLABLALB_00258 1.09e-87 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KLABLALB_00259 1.17e-35 adhR - - K - - - transcriptional regulator
KLABLALB_00260 8.87e-113 - - - S - - - NADPH-dependent FMN reductase
KLABLALB_00261 3.49e-130 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KLABLALB_00262 1.14e-70 - - - S - - - ECF transporter, substrate-specific component
KLABLALB_00263 6.01e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
KLABLALB_00264 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KLABLALB_00265 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KLABLALB_00266 1.08e-45 - - - - - - - -
KLABLALB_00267 3.04e-20 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
KLABLALB_00268 2.21e-73 - - - S - - - Protein of unknown function (DUF1129)
KLABLALB_00269 2.41e-241 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLABLALB_00270 3.11e-33 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KLABLALB_00271 2.39e-137 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KLABLALB_00272 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KLABLALB_00273 6.46e-85 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KLABLALB_00274 7.29e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KLABLALB_00275 4.74e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KLABLALB_00276 2.48e-89 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
KLABLALB_00278 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KLABLALB_00279 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
KLABLALB_00280 6.05e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KLABLALB_00282 2.06e-82 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KLABLALB_00283 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KLABLALB_00284 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KLABLALB_00285 1.75e-45 - - - - - - - -
KLABLALB_00286 1.86e-178 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLABLALB_00287 1.42e-197 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLABLALB_00288 1.11e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLABLALB_00289 1.91e-197 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KLABLALB_00290 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
KLABLALB_00292 3.12e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00293 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
KLABLALB_00294 2.84e-234 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
KLABLALB_00295 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLABLALB_00296 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KLABLALB_00297 6.4e-138 - - - P - - - Integral membrane protein TerC family
KLABLALB_00298 1.86e-49 - - - K - - - Transcriptional regulator
KLABLALB_00299 3.36e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KLABLALB_00300 1.17e-127 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00301 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KLABLALB_00302 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLABLALB_00303 1.25e-256 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
KLABLALB_00304 2.84e-220 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
KLABLALB_00305 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KLABLALB_00306 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
KLABLALB_00307 4.9e-89 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
KLABLALB_00308 8.78e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
KLABLALB_00309 3.63e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
KLABLALB_00310 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
KLABLALB_00311 8.13e-71 - - - - - - - -
KLABLALB_00313 5.03e-48 - - - V - - - Type I restriction modification DNA specificity domain
KLABLALB_00314 8.77e-263 - - - V - - - N-6 DNA Methylase
KLABLALB_00315 2.37e-29 - - - S - - - PIN domain
KLABLALB_00316 1.64e-06 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
KLABLALB_00317 4.75e-91 - - - DM - - - Glucan-binding protein C
KLABLALB_00318 1.71e-97 azlC - - E - - - branched-chain amino acid
KLABLALB_00319 3.78e-74 - - - F - - - Nucleoside 2-deoxyribosyltransferase
KLABLALB_00320 3.49e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KLABLALB_00321 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KLABLALB_00322 2.67e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
KLABLALB_00323 4.35e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
KLABLALB_00326 2.41e-101 - - - S - - - Cell surface protein
KLABLALB_00328 1.01e-229 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KLABLALB_00329 4.31e-55 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KLABLALB_00330 4.79e-42 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KLABLALB_00332 6.17e-77 yciB - - M - - - ErfK YbiS YcfS YnhG
KLABLALB_00333 1.05e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
KLABLALB_00334 5.71e-225 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLABLALB_00335 6.53e-283 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLABLALB_00336 2.12e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLABLALB_00337 1.53e-181 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLABLALB_00339 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
KLABLALB_00340 7.46e-116 yunF - - F - - - Protein of unknown function DUF72
KLABLALB_00341 6.62e-196 yngD - - S ko:K07097 - ko00000 DHHA1 domain
KLABLALB_00342 5.16e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLABLALB_00343 4.12e-75 - - - - - - - -
KLABLALB_00344 1.91e-53 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KLABLALB_00345 9.05e-30 - - - S - - - Cytochrome B5
KLABLALB_00347 1.3e-24 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KLABLALB_00348 3.65e-241 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLABLALB_00349 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KLABLALB_00350 1.42e-135 yueF - - S - - - AI-2E family transporter
KLABLALB_00351 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KLABLALB_00352 9.84e-147 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KLABLALB_00353 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLABLALB_00354 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
KLABLALB_00355 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
KLABLALB_00356 2.26e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KLABLALB_00357 1.07e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLABLALB_00358 1.04e-206 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KLABLALB_00359 1.15e-250 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KLABLALB_00360 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KLABLALB_00361 6.64e-131 - - - G - - - MucBP domain
KLABLALB_00362 3.55e-31 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
KLABLALB_00363 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KLABLALB_00364 1.5e-22 - - - - - - - -
KLABLALB_00365 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KLABLALB_00366 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLABLALB_00367 2.09e-202 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KLABLALB_00368 3.2e-164 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KLABLALB_00369 8.79e-166 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLABLALB_00370 1.41e-35 ykuJ - - S - - - Protein of unknown function (DUF1797)
KLABLALB_00371 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLABLALB_00372 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KLABLALB_00373 2.31e-239 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLABLALB_00374 9.13e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
KLABLALB_00375 1.01e-143 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
KLABLALB_00376 4.55e-105 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KLABLALB_00377 3.87e-82 - - - - - - - -
KLABLALB_00378 9.71e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
KLABLALB_00379 2.35e-52 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KLABLALB_00380 1.57e-59 - - - M - - - Chain length determinant protein
KLABLALB_00381 6.61e-83 - - - D - - - AAA domain
KLABLALB_00382 1.61e-153 capD - - M - - - Psort location CytoplasmicMembrane, score
KLABLALB_00383 1.34e-104 - - - GM - - - CoA-binding domain
KLABLALB_00384 1.86e-59 epsN - - M ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
KLABLALB_00385 7.69e-137 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KLABLALB_00386 2.94e-98 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
KLABLALB_00387 2.02e-52 - - - S ko:K13006,ko:K19429 - ko00000,ko01000,ko01005 Bacterial transferase hexapeptide (six repeats)
KLABLALB_00388 2.09e-99 - - - M - - - Glycosyl transferases group 1
KLABLALB_00389 1.15e-49 - - GT4 M ko:K13004 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase 4-like
KLABLALB_00390 1.13e-97 - - - M - - - glycosyl transferase group 1
KLABLALB_00391 4.2e-92 - - - M - - - glycosyl transferase group 1
KLABLALB_00392 1.84e-88 - - - M - - - Glycosyltransferase Family 4
KLABLALB_00393 1.19e-46 rfbF - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
KLABLALB_00394 3.65e-70 - - - M - - - Glycosyltransferase like family 2
KLABLALB_00397 3.45e-51 - - - - - - - -
KLABLALB_00398 5.75e-146 - - - S - - - Glycosyltransferase WbsX
KLABLALB_00399 2.54e-12 - - - M - - - Glycosyl transferases group 1
KLABLALB_00400 3.08e-32 - - - M - - - Glycosyl transferase
KLABLALB_00401 1.04e-99 - - - S - - - Psort location CytoplasmicMembrane, score
KLABLALB_00403 1.02e-181 - 5.1.3.6 - GM ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 RmlD substrate binding domain
KLABLALB_00404 3.52e-225 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KLABLALB_00405 3.98e-06 - - GT4 M ko:K12989 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferases group 1
KLABLALB_00406 3.59e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KLABLALB_00407 3.98e-253 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KLABLALB_00408 5.9e-178 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KLABLALB_00409 6.73e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KLABLALB_00410 4.63e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLABLALB_00411 5.92e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KLABLALB_00412 1.99e-87 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLABLALB_00413 8.4e-196 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KLABLALB_00414 4.22e-106 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
KLABLALB_00415 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KLABLALB_00416 1.12e-15 - - - M - - - Lysin motif
KLABLALB_00417 4.88e-153 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KLABLALB_00418 1.2e-78 - - - S - - - Helix-turn-helix domain
KLABLALB_00419 2.54e-276 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KLABLALB_00420 1.18e-69 - - - F - - - glutamine amidotransferase
KLABLALB_00421 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KLABLALB_00422 2.47e-146 degV - - S - - - EDD domain protein, DegV family
KLABLALB_00423 4.84e-291 cadA - - P - - - P-type ATPase
KLABLALB_00424 0.0 - - - E - - - Amino acid permease
KLABLALB_00425 2.22e-108 - - - S - - - Membrane
KLABLALB_00426 3.27e-57 cps3F - - - - - - -
KLABLALB_00427 6.47e-125 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLABLALB_00428 5.31e-23 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KLABLALB_00429 1.36e-169 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KLABLALB_00430 3.01e-143 - - - - - - - -
KLABLALB_00431 1.14e-147 - - - - - - - -
KLABLALB_00432 1.45e-48 - - - S - - - Protein conserved in bacteria
KLABLALB_00433 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLABLALB_00434 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KLABLALB_00435 1.45e-46 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLABLALB_00436 3.85e-132 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLABLALB_00437 3.49e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLABLALB_00438 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLABLALB_00439 4.39e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KLABLALB_00440 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KLABLALB_00441 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KLABLALB_00442 1.17e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KLABLALB_00443 1.83e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLABLALB_00444 7.41e-41 ynzC - - S - - - UPF0291 protein
KLABLALB_00445 3.98e-36 yneF - - S ko:K09976 - ko00000 UPF0154 protein
KLABLALB_00446 3.24e-118 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KLABLALB_00447 1.25e-57 - - - S - - - mazG nucleotide pyrophosphohydrolase
KLABLALB_00448 4.49e-49 yciQ - - P - - - membrane protein (DUF2207)
KLABLALB_00449 6.07e-186 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLABLALB_00450 5.98e-171 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KLABLALB_00451 1.95e-102 - - - S - - - L,D-transpeptidase catalytic domain
KLABLALB_00452 1.5e-38 - - - S - - - CRISPR-associated protein (Cas_Csn2)
KLABLALB_00453 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLABLALB_00457 4.35e-48 - - - L ko:K07497 - ko00000 hmm pf00665
KLABLALB_00458 5.89e-60 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
KLABLALB_00459 8.18e-22 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
KLABLALB_00461 6.72e-111 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLABLALB_00462 2.56e-42 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLABLALB_00463 2.08e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KLABLALB_00464 1.14e-92 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
KLABLALB_00465 6.41e-167 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
KLABLALB_00466 6.89e-127 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KLABLALB_00467 3.84e-105 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KLABLALB_00468 6.62e-11 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KLABLALB_00470 6.8e-185 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLABLALB_00471 3.5e-18 - - - - - - - -
KLABLALB_00472 8.82e-154 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KLABLALB_00473 1.74e-235 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLABLALB_00474 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLABLALB_00475 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
KLABLALB_00476 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLABLALB_00477 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
KLABLALB_00478 3e-16 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KLABLALB_00479 7.68e-20 cvpA - - S - - - Colicin V production protein
KLABLALB_00480 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLABLALB_00481 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KLABLALB_00482 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
KLABLALB_00483 6.33e-89 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLABLALB_00484 7.32e-53 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KLABLALB_00487 1.41e-177 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLABLALB_00488 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLABLALB_00489 1.35e-271 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLABLALB_00490 3.6e-255 oatA - - I - - - Acyltransferase
KLABLALB_00491 1.68e-22 - - - - - - - -
KLABLALB_00493 4.32e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLABLALB_00494 4.8e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
KLABLALB_00495 4.1e-267 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KLABLALB_00496 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLABLALB_00497 0.0 - - - S - - - membrane
KLABLALB_00498 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KLABLALB_00499 1.21e-35 - - - S - - - Protein of unknown function (DUF3290)
KLABLALB_00500 1.03e-96 yviA - - S - - - Protein of unknown function (DUF421)
KLABLALB_00502 2.41e-157 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KLABLALB_00503 5.17e-253 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KLABLALB_00504 4.17e-70 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KLABLALB_00505 9.48e-97 uspA - - T - - - universal stress protein
KLABLALB_00507 3.67e-244 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KLABLALB_00508 2.29e-28 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KLABLALB_00509 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLABLALB_00510 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KLABLALB_00511 3.25e-223 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLABLALB_00512 1.45e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KLABLALB_00513 1.01e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLABLALB_00514 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLABLALB_00515 1.71e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KLABLALB_00516 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
KLABLALB_00517 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
KLABLALB_00518 2.35e-207 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KLABLALB_00519 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KLABLALB_00520 9.34e-71 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
KLABLALB_00521 1.02e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KLABLALB_00522 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
KLABLALB_00523 9.11e-53 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KLABLALB_00524 1.22e-238 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KLABLALB_00525 9.2e-73 - - - S - - - Calcineurin-like phosphoesterase
KLABLALB_00526 3.71e-78 yutD - - S - - - Protein of unknown function (DUF1027)
KLABLALB_00527 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLABLALB_00528 4.54e-38 - - - S - - - Protein of unknown function (DUF1461)
KLABLALB_00529 1.08e-117 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KLABLALB_00530 4.05e-119 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KLABLALB_00531 1.72e-65 yugI - - J ko:K07570 - ko00000 general stress protein
KLABLALB_00532 5.01e-33 - - - S - - - Glycosyl hydrolases family 25
KLABLALB_00533 5.05e-154 - - - M - - - Glycosyl transferases group 1
KLABLALB_00542 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KLABLALB_00543 4.46e-70 jag - - S ko:K06346 - ko00000 R3H domain protein
KLABLALB_00544 1.3e-67 - - - K - - - Transcriptional regulator C-terminal region
KLABLALB_00545 8.75e-60 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
KLABLALB_00546 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KLABLALB_00547 3.19e-139 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
KLABLALB_00549 2.05e-86 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KLABLALB_00550 5.56e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
KLABLALB_00551 1.3e-52 - - - K - - - Acetyltransferase GNAT Family
KLABLALB_00553 4.2e-45 aguA 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Porphyromonas-type peptidyl-arginine deiminase
KLABLALB_00554 4.86e-259 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KLABLALB_00555 3.24e-35 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KLABLALB_00556 6.7e-122 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00557 1.34e-14 - - - K - - - Transcriptional regulator C-terminal region
KLABLALB_00562 1.34e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KLABLALB_00563 1.64e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KLABLALB_00564 3.4e-93 - - - M - - - GNAT acetyltransferase
KLABLALB_00566 5.57e-12 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
KLABLALB_00567 8.33e-13 - - - D - - - Antitoxin Phd_YefM, type II toxin-antitoxin system
KLABLALB_00568 8.44e-246 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KLABLALB_00569 5.59e-84 ypsA - - S - - - Belongs to the UPF0398 family
KLABLALB_00570 1.52e-236 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KLABLALB_00571 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLABLALB_00572 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KLABLALB_00573 1.02e-132 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KLABLALB_00577 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
KLABLALB_00578 8.22e-240 steT - - E ko:K03294 - ko00000 amino acid
KLABLALB_00579 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00580 3.9e-23 - - - K - - - Bacterial regulatory proteins, tetR family
KLABLALB_00582 2.66e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00583 8.83e-316 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
KLABLALB_00584 1.29e-11 - - - - - - - -
KLABLALB_00585 1.41e-48 yyaT - - K ko:K02348 - ko00000 protein acetylation
KLABLALB_00586 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
KLABLALB_00587 2.31e-94 lemA - - S ko:K03744 - ko00000 LemA family
KLABLALB_00588 2.51e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KLABLALB_00590 0.0 - - - L - - - DNA helicase
KLABLALB_00591 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLABLALB_00592 3.88e-29 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KLABLALB_00593 8.99e-168 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KLABLALB_00594 1.06e-126 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
KLABLALB_00595 5.21e-20 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KLABLALB_00596 3.83e-116 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KLABLALB_00597 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLABLALB_00598 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLABLALB_00599 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLABLALB_00600 3.15e-29 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KLABLALB_00601 5.8e-106 - - - K - - - Bacterial regulatory proteins, tetR family
KLABLALB_00602 2.49e-190 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KLABLALB_00603 7.79e-50 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KLABLALB_00604 4.95e-265 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KLABLALB_00605 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLABLALB_00606 3.94e-106 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KLABLALB_00607 3.91e-122 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLABLALB_00608 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLABLALB_00609 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
KLABLALB_00610 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
KLABLALB_00611 2.14e-99 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
KLABLALB_00613 6.15e-73 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLABLALB_00614 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLABLALB_00615 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00616 9.61e-166 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLABLALB_00617 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLABLALB_00618 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLABLALB_00619 1.91e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
KLABLALB_00621 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KLABLALB_00622 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KLABLALB_00623 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KLABLALB_00626 9.18e-69 - - - M - - - Glycosyltransferase like family 2
KLABLALB_00627 9.39e-52 - - - M - - - Glycosyltransferase like family 2
KLABLALB_00628 1.49e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
KLABLALB_00629 5.9e-117 - - - M - - - transferase activity, transferring glycosyl groups
KLABLALB_00630 3.06e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLABLALB_00631 6.01e-100 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLABLALB_00632 4.21e-106 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLABLALB_00633 2.93e-71 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
KLABLALB_00634 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KLABLALB_00635 2.23e-181 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KLABLALB_00636 1.55e-45 ypmB - - S - - - Protein conserved in bacteria
KLABLALB_00637 1.87e-271 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KLABLALB_00638 2.58e-119 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KLABLALB_00639 1.78e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KLABLALB_00640 2.3e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KLABLALB_00641 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLABLALB_00642 5.61e-73 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KLABLALB_00646 3.02e-157 - - - L - - - AAA domain
KLABLALB_00647 1.76e-38 - - - S - - - Protein of unknown function (DUF669)
KLABLALB_00648 2.45e-218 - - - L - - - DNA polymerase elongation subunit (Family B)
KLABLALB_00649 7.16e-30 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4 family
KLABLALB_00650 9.26e-144 - - - L ko:K06919 - ko00000 Phage plasmid primase, P4 family
KLABLALB_00655 1.09e-11 - - - - - - - -
KLABLALB_00656 1.11e-30 - - - S - - - HNH endonuclease
KLABLALB_00657 1.67e-71 - - - L - - - Belongs to the 'phage' integrase family
KLABLALB_00659 9.92e-87 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KLABLALB_00671 2.55e-23 - - - L - - - HNH endonuclease
KLABLALB_00672 9.49e-43 - - - L - - - Phage terminase, small subunit
KLABLALB_00673 2.29e-269 - - - S - - - Terminase
KLABLALB_00674 6.09e-129 - - - S - - - Phage portal protein, HK97 family
KLABLALB_00675 3.87e-90 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
KLABLALB_00676 1.06e-117 - - - S - - - Phage capsid family
KLABLALB_00683 1.36e-132 - - - L - - - Phage tail tape measure protein TP901
KLABLALB_00684 3.76e-116 - - - S - - - Phage tail protein
KLABLALB_00685 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
KLABLALB_00686 3.32e-121 - - - M - - - Prophage endopeptidase tail
KLABLALB_00687 3.46e-107 - - - S - - - (CBS) domain
KLABLALB_00688 3.13e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLABLALB_00689 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLABLALB_00690 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KLABLALB_00691 8.18e-73 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KLABLALB_00692 3.92e-76 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KLABLALB_00693 1.33e-05 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KLABLALB_00694 1.43e-60 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
KLABLALB_00695 1.17e-141 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLABLALB_00696 2.6e-62 - - - M - - - LysM domain protein
KLABLALB_00697 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KLABLALB_00698 3.7e-110 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KLABLALB_00699 2.98e-41 - - - K - - - transcriptional regulator (TetR family)
KLABLALB_00700 2.16e-137 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KLABLALB_00701 3.65e-110 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00702 3.37e-84 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KLABLALB_00703 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KLABLALB_00704 4.89e-308 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KLABLALB_00706 2.14e-92 licD1 - - M ko:K07271 - ko00000,ko01000 LicD family
KLABLALB_00707 6.55e-41 - - - - - - - -
KLABLALB_00708 2.73e-289 - - - M - - - Rib/alpha-like repeat
KLABLALB_00710 1.7e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
KLABLALB_00711 9.53e-79 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
KLABLALB_00712 1.54e-203 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLABLALB_00713 3.36e-48 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KLABLALB_00714 1.09e-268 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KLABLALB_00715 3.94e-249 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KLABLALB_00716 4.35e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLABLALB_00717 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
KLABLALB_00718 7.05e-222 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KLABLALB_00719 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLABLALB_00720 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLABLALB_00721 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KLABLALB_00722 1.86e-81 ywlG - - S - - - Belongs to the UPF0340 family
KLABLALB_00723 7.36e-189 - - - C - - - Oxidoreductase
KLABLALB_00724 1.62e-61 - - - - - - - -
KLABLALB_00725 3.66e-53 - - - S - - - Protein of unknown function (DUF4065)
KLABLALB_00726 3.36e-45 - - - S - - - Phage transcriptional regulator, ArpU family
KLABLALB_00740 2e-89 - - - - - - - -
KLABLALB_00741 4.18e-28 - - - - - - - -
KLABLALB_00744 6.52e-31 - - - L - - - N-terminal phage replisome organiser (Phage_rep_org_N)
KLABLALB_00745 5.71e-68 - - - S - - - Putative HNHc nuclease
KLABLALB_00751 5.78e-72 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
KLABLALB_00752 1.44e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
KLABLALB_00755 1.11e-32 - - - K - - - Cro/C1-type HTH DNA-binding domain
KLABLALB_00757 1.45e-23 - - - - - - - -
KLABLALB_00759 4.57e-50 - - - K - - - Peptidase S24-like
KLABLALB_00761 9e-09 - - - - - - - -
KLABLALB_00763 6.46e-68 - - - - - - - -
KLABLALB_00764 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLABLALB_00765 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLABLALB_00766 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KLABLALB_00769 1.27e-115 - - - M - - - Prophage endopeptidase tail
KLABLALB_00771 3.95e-126 - - - S - - - peptidoglycan catabolic process
KLABLALB_00772 6.29e-49 - - - S - - - Bacteriophage Gp15 protein
KLABLALB_00774 8.63e-49 - - - N - - - domain, Protein
KLABLALB_00777 1.25e-37 - - - S - - - Minor capsid protein
KLABLALB_00779 2.04e-123 - - - S - - - T=7 icosahedral viral capsid
KLABLALB_00780 3.01e-26 - - - S - - - Phage minor structural protein GP20
KLABLALB_00782 1.51e-114 - - - S - - - Phage minor capsid protein 2
KLABLALB_00783 2.18e-176 - - - S - - - Phage portal protein, SPP1 Gp6-like
KLABLALB_00784 6.43e-208 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
KLABLALB_00785 1.53e-27 - - - - - - - -
KLABLALB_00787 1.78e-261 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KLABLALB_00788 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KLABLALB_00790 1.61e-101 - - - F - - - Hydrolase, nudix family
KLABLALB_00791 8.16e-20 prsA 5.2.1.8 - O ko:K02597,ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl cis-trans isomerase activity
KLABLALB_00792 6.56e-163 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
KLABLALB_00793 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
KLABLALB_00794 1.07e-63 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KLABLALB_00795 7.33e-276 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KLABLALB_00798 9.23e-115 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KLABLALB_00799 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLABLALB_00800 1.39e-91 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLABLALB_00801 2.26e-59 ykuL - - S - - - CBS domain
KLABLALB_00802 1.05e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
KLABLALB_00803 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLABLALB_00804 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KLABLALB_00805 6.3e-290 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLABLALB_00806 7.35e-140 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
KLABLALB_00807 1.73e-129 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
KLABLALB_00808 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLABLALB_00809 2.06e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
KLABLALB_00810 4.61e-84 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLABLALB_00811 4.05e-61 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLABLALB_00812 4.97e-248 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLABLALB_00813 6.31e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KLABLALB_00814 5.4e-92 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KLABLALB_00815 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLABLALB_00816 2.12e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLABLALB_00817 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
KLABLALB_00818 9.26e-87 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLABLALB_00819 1.56e-46 - - - L - - - PLD-like domain
KLABLALB_00820 1.51e-160 - - - L - - - PLD-like domain
KLABLALB_00821 1.82e-100 - - - S - - - Fic/DOC family
KLABLALB_00822 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KLABLALB_00823 9.75e-78 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
KLABLALB_00824 2.62e-52 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLABLALB_00825 1.36e-47 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KLABLALB_00826 1.46e-233 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KLABLALB_00827 8.33e-151 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
KLABLALB_00828 7.62e-217 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
KLABLALB_00829 1.38e-113 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KLABLALB_00830 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLABLALB_00831 3.32e-288 fusA1 - - J - - - elongation factor G
KLABLALB_00832 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLABLALB_00833 1.16e-08 - - - - - - - -
KLABLALB_00834 2.16e-271 potE - - E - - - Amino Acid
KLABLALB_00836 2.33e-95 - - - K - - - Helix-turn-helix domain, rpiR family
KLABLALB_00837 7.47e-117 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KLABLALB_00838 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KLABLALB_00839 2.9e-114 nanK - - GK - - - ROK family
KLABLALB_00840 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
KLABLALB_00841 1.74e-80 - - - G - - - Xylose isomerase domain protein TIM barrel
KLABLALB_00842 2.19e-191 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLABLALB_00843 1.02e-259 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLABLALB_00844 4.48e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
KLABLALB_00845 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KLABLALB_00846 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
KLABLALB_00847 2.27e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
KLABLALB_00848 2.3e-103 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
KLABLALB_00849 1.9e-235 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KLABLALB_00851 1.94e-18 - - - - - - - -
KLABLALB_00852 3.14e-50 blpT - - - - - - -
KLABLALB_00860 3.53e-158 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLABLALB_00861 1.81e-216 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KLABLALB_00862 5.27e-123 ydbI - - K - - - AI-2E family transporter
KLABLALB_00863 2.37e-75 - - - EG - - - EamA-like transporter family
KLABLALB_00864 1.3e-97 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
KLABLALB_00865 4.86e-148 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KLABLALB_00866 4.46e-86 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KLABLALB_00867 5.43e-209 - - - C - - - Luciferase-like monooxygenase
KLABLALB_00868 1.7e-55 hxlR - - K - - - Transcriptional regulator, HxlR family
KLABLALB_00869 6.68e-219 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KLABLALB_00870 2.09e-132 gntR - - K - - - UbiC transcription regulator-associated domain protein
KLABLALB_00871 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KLABLALB_00872 3.43e-106 pncA - - Q - - - isochorismatase
KLABLALB_00873 1.87e-80 pgm1 - - G - - - phosphoglycerate mutase
KLABLALB_00874 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KLABLALB_00875 1.68e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
KLABLALB_00876 5.26e-316 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KLABLALB_00877 2.77e-211 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KLABLALB_00879 1.61e-229 XK27_08315 - - M - - - Sulfatase
KLABLALB_00880 2.45e-66 - - - S - - - peptidoglycan catabolic process
KLABLALB_00881 3.48e-196 caiT - - M ko:K03451 - ko00000 BCCT, betaine/carnitine/choline family transporter
KLABLALB_00882 1.7e-87 - - - M - - - Nucleotidyl transferase
KLABLALB_00883 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KLABLALB_00884 3.2e-81 - - - D - - - peptidase
KLABLALB_00885 6.63e-148 - - - S - - - Glycosyl transferase family 2
KLABLALB_00886 1.35e-136 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
KLABLALB_00887 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLABLALB_00888 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLABLALB_00889 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KLABLALB_00890 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLABLALB_00891 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLABLALB_00892 2.79e-192 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLABLALB_00893 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KLABLALB_00894 1.81e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLABLALB_00895 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLABLALB_00896 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KLABLALB_00897 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLABLALB_00898 1.54e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLABLALB_00899 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
KLABLALB_00900 2.23e-150 - - - S - - - Conserved hypothetical protein 698
KLABLALB_00901 1.77e-67 - - - K - - - LysR substrate binding domain
KLABLALB_00903 9.38e-81 icaB - - G - - - Polysaccharide deacetylase
KLABLALB_00904 3.46e-39 - - - S - - - Belongs to the HesB IscA family
KLABLALB_00905 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLABLALB_00906 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLABLALB_00907 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
KLABLALB_00908 3.91e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KLABLALB_00909 1.11e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KLABLALB_00910 2.23e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLABLALB_00911 7.73e-268 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLABLALB_00912 3.64e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLABLALB_00913 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLABLALB_00914 2.93e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
KLABLALB_00915 3.09e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLABLALB_00916 3.28e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KLABLALB_00917 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
KLABLALB_00918 7.55e-120 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLABLALB_00919 6.03e-105 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KLABLALB_00920 1.63e-177 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
KLABLALB_00921 6.07e-87 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KLABLALB_00922 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KLABLALB_00923 2.51e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLABLALB_00924 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KLABLALB_00925 2.16e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLABLALB_00926 1.43e-41 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
KLABLALB_00927 1.98e-45 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLABLALB_00928 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLABLALB_00929 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
KLABLALB_00930 0.0 ydaO - - E - - - amino acid
KLABLALB_00931 2.25e-56 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KLABLALB_00932 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLABLALB_00933 4.77e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLABLALB_00934 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLABLALB_00935 1.01e-281 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLABLALB_00936 3.28e-173 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KLABLALB_00937 6.95e-96 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLABLALB_00938 1.4e-291 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KLABLALB_00939 1.86e-200 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KLABLALB_00940 3.92e-138 - - - S - - - Acyltransferase family
KLABLALB_00941 1.59e-241 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLABLALB_00942 2.58e-156 - - - K - - - LysR substrate binding domain
KLABLALB_00944 6.94e-28 - - - - - - - -
KLABLALB_00945 1.03e-65 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KLABLALB_00946 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KLABLALB_00947 9.6e-61 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KLABLALB_00948 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KLABLALB_00949 7.23e-168 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KLABLALB_00950 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KLABLALB_00951 1.41e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_00952 5.62e-139 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KLABLALB_00953 9.13e-124 ybcH - - D ko:K06889 - ko00000 Alpha beta
KLABLALB_00954 4.23e-06 - - - S - - - Protein of unknown function (DUF4044)
KLABLALB_00955 2.55e-194 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
KLABLALB_00957 5.35e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KLABLALB_00958 1.05e-179 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLABLALB_00959 1.49e-13 ftsL - - D - - - Essential cell division protein
KLABLALB_00960 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KLABLALB_00961 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLABLALB_00962 2.37e-222 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLABLALB_00963 2.12e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLABLALB_00964 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLABLALB_00965 1.22e-239 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLABLALB_00966 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLABLALB_00967 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLABLALB_00968 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
KLABLALB_00969 1.4e-104 ylmH - - S - - - S4 domain protein
KLABLALB_00970 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KLABLALB_00971 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLABLALB_00972 4.52e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLABLALB_00973 5.69e-91 - - - O - - - ADP-ribosylglycohydrolase
KLABLALB_00975 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
KLABLALB_00976 1.29e-114 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
KLABLALB_00977 1.8e-67 - - - M - - - LysM domain protein
KLABLALB_00978 1.38e-25 - - - P - - - Rhodanese Homology Domain
KLABLALB_00979 6.38e-47 - - - M - - - LysM domain
KLABLALB_00980 4.47e-201 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KLABLALB_00981 1.84e-244 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
KLABLALB_00982 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
KLABLALB_00983 5.44e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KLABLALB_00984 1.63e-274 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
KLABLALB_00985 1.86e-120 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KLABLALB_00986 6.63e-132 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KLABLALB_00987 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
KLABLALB_00988 4.76e-181 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
KLABLALB_00989 1.4e-52 - - - - - - - -
KLABLALB_00994 2.73e-215 potE2 - - E ko:K03294 - ko00000 amino acid
KLABLALB_00995 2.23e-184 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KLABLALB_00996 1.11e-147 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KLABLALB_00997 1.61e-75 - - - K - - - Domain of unknown function (DUF1836)
KLABLALB_00998 2.66e-101 yitS - - S - - - EDD domain protein, DegV family
KLABLALB_00999 3.77e-57 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KLABLALB_01001 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLABLALB_01002 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
KLABLALB_01003 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
KLABLALB_01004 2.79e-110 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
KLABLALB_01007 2.14e-67 - - - C - - - Oxidoreductase NAD-binding domain
KLABLALB_01008 6.14e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
KLABLALB_01009 2.85e-197 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
KLABLALB_01010 2.08e-120 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
KLABLALB_01011 8.3e-160 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
KLABLALB_01012 2.58e-53 - - - L ko:K07497 - ko00000 hmm pf00665
KLABLALB_01013 1.32e-33 - - - L ko:K07498 - ko00000 Transposase
KLABLALB_01014 3.43e-45 - - - P - - - Heavy-metal-associated domain
KLABLALB_01015 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
KLABLALB_01016 1.09e-25 - - - L ko:K07483 - ko00000 PFAM transposase IS3 IS911 family protein
KLABLALB_01017 5.92e-101 - - - L ko:K07497 - ko00000 Integrase core domain
KLABLALB_01018 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
KLABLALB_01019 8.06e-122 - - - EGP - - - Major Facilitator Superfamily
KLABLALB_01020 2.63e-89 - - - K - - - Transcriptional regulator, LysR family
KLABLALB_01021 7.4e-177 - - - G - - - Xylose isomerase-like TIM barrel
KLABLALB_01022 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KLABLALB_01023 2.95e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KLABLALB_01024 5.13e-176 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KLABLALB_01025 4.79e-89 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KLABLALB_01026 4.43e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
KLABLALB_01027 1.86e-222 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLABLALB_01028 4.02e-63 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLABLALB_01029 6.02e-65 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLABLALB_01030 5.32e-63 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLABLALB_01031 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLABLALB_01032 2.46e-95 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
KLABLALB_01033 4.56e-79 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KLABLALB_01034 1.57e-42 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KLABLALB_01035 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLABLALB_01036 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLABLALB_01037 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KLABLALB_01038 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLABLALB_01039 2.34e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KLABLALB_01040 2.94e-229 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KLABLALB_01041 5.2e-225 - - - S - - - Protein of unknown function DUF262
KLABLALB_01043 1.26e-48 - - - - - - - -
KLABLALB_01044 2.07e-29 - - - V ko:K07448,ko:K07449 - ko00000,ko02048 Restriction endonuclease
KLABLALB_01045 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KLABLALB_01046 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLABLALB_01047 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLABLALB_01048 1.64e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KLABLALB_01049 1.56e-42 yabO - - J - - - S4 domain protein
KLABLALB_01050 2e-26 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KLABLALB_01051 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
KLABLALB_01052 1.14e-118 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLABLALB_01053 2.04e-99 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KLABLALB_01054 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLABLALB_01055 2.65e-166 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLABLALB_01056 9.77e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLABLALB_01057 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KLABLALB_01058 1.8e-272 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLABLALB_01059 7.59e-185 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
KLABLALB_01060 7.89e-42 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KLABLALB_01061 1.06e-131 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KLABLALB_01063 2.07e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLABLALB_01064 1.5e-141 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KLABLALB_01065 9.26e-253 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
KLABLALB_01066 2.65e-35 - - - - - - - -
KLABLALB_01067 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
KLABLALB_01068 4.99e-78 - - - T - - - Universal stress protein family
KLABLALB_01070 7.69e-272 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KLABLALB_01071 3.5e-214 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
KLABLALB_01072 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLABLALB_01073 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KLABLALB_01074 1.36e-72 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLABLALB_01075 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLABLALB_01076 1.21e-96 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KLABLALB_01077 1.65e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLABLALB_01078 3.67e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLABLALB_01079 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLABLALB_01080 4.38e-35 ylxQ - - J - - - ribosomal protein
KLABLALB_01081 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KLABLALB_01082 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KLABLALB_01083 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KLABLALB_01084 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLABLALB_01085 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLABLALB_01086 2.92e-195 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KLABLALB_01087 6.42e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KLABLALB_01088 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLABLALB_01089 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLABLALB_01090 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KLABLALB_01091 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
KLABLALB_01092 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLABLALB_01094 6.4e-152 - - - V ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KLABLALB_01095 4.9e-158 - - - V ko:K20460,ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KLABLALB_01096 1.11e-207 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KLABLALB_01097 2.3e-159 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLABLALB_01098 6.35e-296 - - - T - - - Histidine kinase
KLABLALB_01103 7.09e-43 - - - S - - - Acyltransferase family
KLABLALB_01104 9.57e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KLABLALB_01105 2.97e-193 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KLABLALB_01107 1.63e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KLABLALB_01108 1.07e-100 - - - K - - - rpiR family
KLABLALB_01109 2.1e-218 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLABLALB_01110 3.24e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KLABLALB_01111 4.2e-132 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLABLALB_01112 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KLABLALB_01113 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLABLALB_01114 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLABLALB_01115 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLABLALB_01116 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLABLALB_01117 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLABLALB_01118 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLABLALB_01119 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KLABLALB_01120 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLABLALB_01121 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLABLALB_01122 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLABLALB_01123 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLABLALB_01124 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLABLALB_01125 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLABLALB_01126 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLABLALB_01127 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLABLALB_01128 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLABLALB_01129 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KLABLALB_01130 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KLABLALB_01131 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLABLALB_01132 5.17e-142 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLABLALB_01133 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLABLALB_01134 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KLABLALB_01135 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLABLALB_01136 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLABLALB_01137 2.74e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLABLALB_01138 1.82e-70 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KLABLALB_01139 3.22e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLABLALB_01140 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLABLALB_01141 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLABLALB_01142 6.22e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLABLALB_01143 8.55e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLABLALB_01144 2.29e-79 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KLABLALB_01145 0.0 - - - M - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KLABLALB_01146 3.95e-266 cna - - M - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KLABLALB_01148 1.3e-33 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
KLABLALB_01149 2.5e-103 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
KLABLALB_01151 3.26e-120 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLABLALB_01152 8.55e-187 - - - IQ - - - KR domain
KLABLALB_01154 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
KLABLALB_01155 3.31e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KLABLALB_01156 9.28e-110 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
KLABLALB_01157 1.13e-280 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KLABLALB_01158 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KLABLALB_01159 2.52e-17 - - - - - - - -
KLABLALB_01160 4.91e-79 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KLABLALB_01161 9.24e-73 - - - S - - - Protein of unknown function (DUF975)
KLABLALB_01162 6.7e-187 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KLABLALB_01163 4.36e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KLABLALB_01164 6.36e-229 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLABLALB_01165 7.47e-213 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
KLABLALB_01166 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KLABLALB_01167 1.63e-267 - - - M - - - LPXTG-motif cell wall anchor domain protein
KLABLALB_01168 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KLABLALB_01169 7.07e-122 - - - M - - - LPXTG-motif cell wall anchor domain protein
KLABLALB_01171 5.71e-75 - - - S - - - Protein of unknown function (DUF4256)
KLABLALB_01172 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KLABLALB_01173 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KLABLALB_01174 1.53e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLABLALB_01176 1.23e-49 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
KLABLALB_01177 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
KLABLALB_01178 1.17e-52 - - - K - - - Bacterial regulatory proteins, tetR family
KLABLALB_01179 5.18e-74 napB - - K - - - transcriptional
KLABLALB_01180 7.97e-90 mleR - - K - - - LysR family
KLABLALB_01181 6.85e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
KLABLALB_01182 1.24e-161 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
KLABLALB_01183 8.09e-82 - - - S - - - ECF transporter, substrate-specific component
KLABLALB_01184 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KLABLALB_01185 1.31e-94 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLABLALB_01186 9.01e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KLABLALB_01187 2.27e-48 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KLABLALB_01188 5.6e-264 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KLABLALB_01189 1.82e-59 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KLABLALB_01190 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KLABLALB_01191 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLABLALB_01192 1.06e-117 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KLABLALB_01193 3.65e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
KLABLALB_01195 1.96e-54 - - - - - - - -
KLABLALB_01196 1.87e-41 - - - K - - - GNAT family
KLABLALB_01197 6.52e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KLABLALB_01198 1.46e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KLABLALB_01200 6.01e-30 - - - O - - - ADP-ribosylglycohydrolase
KLABLALB_01201 1.46e-272 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KLABLALB_01202 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KLABLALB_01203 1.95e-208 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KLABLALB_01204 1.11e-156 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
KLABLALB_01205 1.82e-243 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KLABLALB_01206 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KLABLALB_01207 3.02e-213 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KLABLALB_01208 7.99e-33 - - - S - - - Domain of unknown function (DUF4828)
KLABLALB_01209 7.62e-161 mocA - - S - - - Oxidoreductase
KLABLALB_01210 2.96e-203 yfmL - - L - - - DEAD DEAH box helicase
KLABLALB_01213 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KLABLALB_01214 1.64e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KLABLALB_01215 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
KLABLALB_01216 1.3e-94 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KLABLALB_01217 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KLABLALB_01218 1.29e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KLABLALB_01219 0.0 - - - E - - - Amino acid permease
KLABLALB_01220 1e-228 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
KLABLALB_01221 1.53e-214 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLABLALB_01222 2.43e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
KLABLALB_01223 1.31e-154 - - - S - - - Sulfite exporter TauE/SafE
KLABLALB_01224 3.98e-151 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
KLABLALB_01225 4.88e-113 - - - S - - - Fic/DOC family
KLABLALB_01227 2.91e-39 - - - - - - - -
KLABLALB_01229 3.76e-18 - - - - - - - -
KLABLALB_01230 7.14e-140 rssA - - S - - - Phospholipase, patatin family
KLABLALB_01231 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLABLALB_01232 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
KLABLALB_01233 6.68e-64 - - - S - - - VIT family
KLABLALB_01234 1.66e-72 - - - L ko:K07487 - ko00000 Transposase DDE domain
KLABLALB_01235 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KLABLALB_01236 1.9e-52 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KLABLALB_01237 5.43e-182 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLABLALB_01238 4.96e-178 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
KLABLALB_01239 1.5e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KLABLALB_01240 3.47e-278 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KLABLALB_01241 5.36e-173 - - - P - - - Voltage gated chloride channel
KLABLALB_01242 5.44e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
KLABLALB_01243 5.44e-173 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KLABLALB_01244 9.61e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KLABLALB_01245 7.5e-60 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
KLABLALB_01246 3.51e-07 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
KLABLALB_01247 1.28e-46 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KLABLALB_01248 8.56e-173 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
KLABLALB_01249 4.75e-107 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
KLABLALB_01250 9.94e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
KLABLALB_01251 5.47e-93 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KLABLALB_01252 8.3e-142 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
KLABLALB_01253 3.46e-34 - - - M - - - by MetaGeneAnnotator
KLABLALB_01254 2e-46 - - - L - - - Phage tail tape measure protein TP901
KLABLALB_01256 1.04e-07 - - - S - - - Phage minor structural protein GP20
KLABLALB_01258 1.01e-34 - - - S - - - Phage Mu protein F like protein
KLABLALB_01259 2.16e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
KLABLALB_01260 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KLABLALB_01262 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
KLABLALB_01263 2.85e-200 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KLABLALB_01264 1.13e-70 oxyR5 - - K - - - Transcriptional regulator
KLABLALB_01265 1.09e-243 - - - C - - - FMN_bind
KLABLALB_01266 5.94e-74 - - - K - - - Peptidase S24-like
KLABLALB_01267 9.1e-17 - - - M - - - Host cell surface-exposed lipoprotein
KLABLALB_01270 3.95e-14 - - - - - - - -
KLABLALB_01271 3.5e-20 - - - - - - - -
KLABLALB_01272 1.13e-144 int3 - - L - - - Belongs to the 'phage' integrase family
KLABLALB_01274 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLABLALB_01275 3.68e-55 - - - S - - - repeat protein
KLABLALB_01276 1.45e-129 pgm - - G - - - Phosphoglycerate mutase family
KLABLALB_01277 1.12e-191 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KLABLALB_01278 1.01e-53 yjbH - - Q - - - Thioredoxin
KLABLALB_01279 3.06e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KLABLALB_01280 2.58e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KLABLALB_01281 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KLABLALB_01282 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLABLALB_01283 3.05e-147 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLABLALB_01284 2.26e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KLABLALB_01285 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KLABLALB_01286 1.39e-100 - - - S - - - VIT family
KLABLALB_01287 2.71e-107 - - - S - - - membrane
KLABLALB_01288 3.9e-24 - - - K - - - Domain of unknown function (DUF1836)
KLABLALB_01289 8.28e-74 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KLABLALB_01290 9.71e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KLABLALB_01291 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLABLALB_01293 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLABLALB_01295 3.6e-87 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
KLABLALB_01296 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KLABLALB_01297 1.84e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
KLABLALB_01298 1.56e-257 ynbB - - P - - - aluminum resistance
KLABLALB_01299 2.47e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLABLALB_01300 6.17e-24 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
KLABLALB_01301 6.86e-59 yqhL - - P - - - Rhodanese-like protein
KLABLALB_01302 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KLABLALB_01303 2.47e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KLABLALB_01304 1.29e-89 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
KLABLALB_01305 5.52e-51 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLABLALB_01306 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KLABLALB_01307 5.29e-218 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KLABLALB_01308 3.61e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KLABLALB_01309 1.21e-53 - - - S - - - VanZ like family
KLABLALB_01310 4e-153 yebC - - K - - - Transcriptional regulatory protein
KLABLALB_01311 1.16e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLABLALB_01312 7.87e-50 - - - L - - - HTH-like domain
KLABLALB_01313 1.8e-113 - - - K - - - IrrE N-terminal-like domain
KLABLALB_01314 1.17e-71 - - - S - - - Fic/DOC family
KLABLALB_01315 2.34e-134 - - - L - - - Belongs to the 'phage' integrase family
KLABLALB_01316 8.84e-54 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KLABLALB_01317 2.78e-23 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KLABLALB_01319 1.82e-140 XK27_09655 - - S - - - Virulence protein RhuM family
KLABLALB_01320 1.03e-157 yvgN - - C - - - Aldo keto reductase
KLABLALB_01321 3.87e-131 - - - S ko:K07089 - ko00000 Predicted permease
KLABLALB_01322 2.85e-34 yeeE - - S ko:K07112 - ko00000 Sulphur transport
KLABLALB_01323 1.08e-32 - - - S - - - Sulphur transport
KLABLALB_01324 3.71e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
KLABLALB_01325 4.79e-148 - - - P - - - Rhodanese Homology Domain
KLABLALB_01327 1.68e-291 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
KLABLALB_01328 1.57e-34 - - - S - - - Psort location Cytoplasmic, score
KLABLALB_01329 8.02e-85 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
KLABLALB_01330 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
KLABLALB_01331 1.19e-91 - - - S - - - An automated process has identified a potential problem with this gene model
KLABLALB_01332 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
KLABLALB_01333 3.01e-182 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
KLABLALB_01334 5.57e-123 - - - S - - - Sulfite exporter TauE/SafE
KLABLALB_01335 1.05e-182 - - - E - - - amino acid
KLABLALB_01336 1.77e-79 - - - E - - - amino acid
KLABLALB_01337 2.05e-61 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
KLABLALB_01339 6.55e-169 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
KLABLALB_01340 1.37e-137 - - - E - - - Serine hydroxymethyltransferase
KLABLALB_01341 3.34e-49 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
KLABLALB_01342 7.08e-88 selA 2.9.1.1 - J ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
KLABLALB_01343 7.55e-38 - - - S - - - Iron-sulfur cluster assembly protein
KLABLALB_01344 3.81e-236 - - - C - - - RnfC Barrel sandwich hybrid domain
KLABLALB_01345 2.9e-125 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
KLABLALB_01346 1.31e-187 - - - S ko:K07112 - ko00000 Sulphur transport
KLABLALB_01347 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
KLABLALB_01348 7.11e-15 - - - GKT - - - COG3711 Transcriptional antiterminator
KLABLALB_01349 5.14e-75 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
KLABLALB_01350 3.31e-231 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
KLABLALB_01351 8.39e-62 - - - S - - - Membrane
KLABLALB_01352 1.8e-94 - - - K - - - helix_turn_helix, arabinose operon control protein
KLABLALB_01353 1.26e-97 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
KLABLALB_01354 1.9e-98 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
KLABLALB_01355 1.26e-272 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KLABLALB_01356 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
KLABLALB_01357 6e-258 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
KLABLALB_01358 1.3e-140 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KLABLALB_01360 2.89e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
KLABLALB_01362 1.63e-135 - - - L - - - Belongs to the 'phage' integrase family
KLABLALB_01364 1.22e-61 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KLABLALB_01366 7.6e-203 - - - L - - - T/G mismatch-specific endonuclease activity
KLABLALB_01367 1.09e-78 - - - - - - - -
KLABLALB_01368 2.16e-07 - - - K - - - Protein of unknown function (DUF4065)
KLABLALB_01372 2.16e-92 - - - S - - - Fic/DOC family
KLABLALB_01373 1.05e-08 - - - K - - - sequence-specific DNA binding
KLABLALB_01374 2.96e-84 - - - D - - - nuclear chromosome segregation
KLABLALB_01376 1.53e-90 - - - - - - - -
KLABLALB_01377 6.58e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KLABLALB_01378 8.5e-277 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
KLABLALB_01379 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KLABLALB_01380 1.72e-229 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLABLALB_01381 8.69e-113 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLABLALB_01382 6.66e-172 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLABLALB_01383 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLABLALB_01384 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KLABLALB_01385 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLABLALB_01386 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLABLALB_01387 1.99e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLABLALB_01388 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLABLALB_01389 3.29e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLABLALB_01390 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLABLALB_01391 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KLABLALB_01392 8.07e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KLABLALB_01393 1.59e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
KLABLALB_01394 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KLABLALB_01395 5.02e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KLABLALB_01396 4.4e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KLABLALB_01397 5.64e-69 gtcA - - S - - - Teichoic acid glycosylation protein
KLABLALB_01398 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
KLABLALB_01399 7.13e-118 - - - L ko:K07482 - ko00000 Integrase core domain
KLABLALB_01400 1.41e-196 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_01401 6.42e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
KLABLALB_01402 1e-135 yxeH - - S - - - hydrolase
KLABLALB_01403 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KLABLALB_01404 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KLABLALB_01405 7.57e-126 yycH - - S - - - YycH protein
KLABLALB_01406 3.11e-28 yycI - - S - - - YycH protein
KLABLALB_01407 3.14e-62 yycI - - S - - - YycH protein
KLABLALB_01408 1.37e-40 - - - S - - - YjbR
KLABLALB_01409 1.46e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KLABLALB_01410 1.76e-186 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KLABLALB_01411 7.88e-94 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLABLALB_01412 1.86e-52 - - - GM - - - NAD(P)H-binding
KLABLALB_01413 7.38e-34 - - - K - - - MarR family transcriptional regulator
KLABLALB_01414 3.84e-112 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KLABLALB_01415 6.03e-19 - - - S - - - PD-(D/E)XK nuclease family transposase
KLABLALB_01418 5.04e-257 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
KLABLALB_01419 2.99e-64 - - - L - - - Helix-turn-helix domain
KLABLALB_01420 9.59e-104 - - - L ko:K07497 - ko00000 hmm pf00665
KLABLALB_01421 9.64e-168 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KLABLALB_01422 2.64e-98 - - - S - - - intracellular protease amidase
KLABLALB_01423 1.96e-29 - - - K - - - transcriptional regulator
KLABLALB_01424 2.37e-188 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KLABLALB_01425 5.2e-57 - - - S - - - Cupredoxin-like domain
KLABLALB_01426 4.15e-26 - - - S - - - Cupredoxin-like domain
KLABLALB_01427 9.35e-314 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KLABLALB_01428 1.28e-77 pgm3 - - G - - - phosphoglycerate mutase family
KLABLALB_01429 7.69e-73 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KLABLALB_01430 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLABLALB_01431 5.46e-276 yifK - - E ko:K03293 - ko00000 Amino acid permease
KLABLALB_01432 2.65e-255 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
KLABLALB_01433 1.97e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLABLALB_01434 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLABLALB_01435 3.5e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KLABLALB_01436 9.89e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KLABLALB_01437 1.85e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
KLABLALB_01438 5.54e-264 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KLABLALB_01439 9.27e-145 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
KLABLALB_01440 2.35e-51 - - - K - - - LytTr DNA-binding domain
KLABLALB_01442 5.32e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
KLABLALB_01443 1.17e-30 - - - K - - - Transcriptional regulator C-terminal region
KLABLALB_01444 1.03e-59 - - - S - - - Short repeat of unknown function (DUF308)
KLABLALB_01445 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLABLALB_01446 8.58e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
KLABLALB_01447 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_01448 2.53e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KLABLALB_01449 4.11e-50 ytcD - - K - - - HxlR-like helix-turn-helix
KLABLALB_01450 9.06e-152 ytbE - - S - - - reductase
KLABLALB_01451 1.16e-93 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLABLALB_01452 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KLABLALB_01455 3.5e-114 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLABLALB_01456 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
KLABLALB_01457 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KLABLALB_01458 3.78e-308 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLABLALB_01459 1.31e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLABLALB_01460 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
KLABLALB_01461 3.25e-54 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KLABLALB_01463 1.02e-145 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLABLALB_01464 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
KLABLALB_01465 1.54e-107 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLABLALB_01466 3.93e-45 - - - S - - - Enterocin A Immunity
KLABLALB_01467 5.18e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KLABLALB_01468 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
KLABLALB_01469 2.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KLABLALB_01470 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLABLALB_01471 1.38e-195 yacL - - S - - - domain protein
KLABLALB_01472 4.97e-311 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLABLALB_01473 2.26e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KLABLALB_01474 4.02e-72 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLABLALB_01475 2.29e-139 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLABLALB_01476 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
KLABLALB_01477 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KLABLALB_01478 6.21e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLABLALB_01479 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KLABLALB_01480 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLABLALB_01481 1.26e-108 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLABLALB_01482 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLABLALB_01483 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLABLALB_01484 7.33e-71 - - - - - - - -
KLABLALB_01485 7.2e-204 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLABLALB_01486 2.85e-126 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLABLALB_01488 1.35e-109 - - - S - - - overlaps another CDS with the same product name
KLABLALB_01489 1.94e-157 yibE - - S - - - overlaps another CDS with the same product name
KLABLALB_01490 2.02e-123 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLABLALB_01491 1.25e-42 ytkL - - S - - - Belongs to the UPF0173 family
KLABLALB_01492 2.88e-23 - - - S - - - Belongs to the UPF0173 family
KLABLALB_01493 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
KLABLALB_01494 5.25e-42 - - - F - - - Phosphorylase superfamily
KLABLALB_01495 8.5e-13 - - - F - - - Phosphorylase superfamily
KLABLALB_01496 1.82e-33 - - - - - - - -
KLABLALB_01497 5.54e-139 dkgB - - S - - - reductase
KLABLALB_01498 1.76e-24 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLABLALB_01499 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLABLALB_01500 1.95e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLABLALB_01501 5.98e-70 - - - EGP - - - Transmembrane secretion effector
KLABLALB_01502 1.05e-174 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KLABLALB_01503 1.2e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
KLABLALB_01504 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLABLALB_01506 1.28e-276 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLABLALB_01507 1.37e-188 - - - G - - - Transporter, major facilitator family protein
KLABLALB_01508 1.37e-111 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KLABLALB_01509 3.05e-190 hpk31 - - T - - - Histidine kinase
KLABLALB_01510 1.21e-145 vanR - - K - - - response regulator
KLABLALB_01511 1.47e-33 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KLABLALB_01513 6.22e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KLABLALB_01514 1.12e-77 - - - S - - - Bacterial membrane protein YfhO
KLABLALB_01515 1.9e-23 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLABLALB_01516 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
KLABLALB_01517 6.07e-214 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KLABLALB_01518 1.16e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
KLABLALB_01519 5.36e-107 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
KLABLALB_01520 2.84e-107 - - - C - - - nitroreductase
KLABLALB_01521 1.85e-167 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
KLABLALB_01522 6.39e-120 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KLABLALB_01523 1.87e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLABLALB_01524 1.72e-134 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KLABLALB_01525 3.1e-178 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KLABLALB_01526 6.97e-58 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
KLABLALB_01527 6.28e-71 yphH - - S - - - Cupin domain
KLABLALB_01528 5.18e-61 - - - C - - - Flavodoxin
KLABLALB_01529 4.51e-69 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KLABLALB_01530 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
KLABLALB_01531 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLABLALB_01532 8.71e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLABLALB_01533 6.58e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLABLALB_01534 2.89e-86 yciB - - M - - - ErfK YbiS YcfS YnhG
KLABLALB_01535 1.41e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_01536 1.13e-145 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KLABLALB_01537 7.9e-169 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_01538 7.13e-201 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KLABLALB_01539 3.11e-133 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KLABLALB_01540 3.16e-152 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KLABLALB_01541 1.28e-211 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLABLALB_01543 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
KLABLALB_01544 1.16e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KLABLALB_01545 1e-85 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_01546 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
KLABLALB_01547 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLABLALB_01548 2.95e-59 ytpP - - CO - - - Thioredoxin
KLABLALB_01549 2.48e-97 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLABLALB_01550 5.61e-297 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KLABLALB_01551 1.24e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KLABLALB_01552 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
KLABLALB_01553 1.25e-87 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KLABLALB_01554 1.55e-146 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
KLABLALB_01556 5.25e-87 yeeC - - P - - - T5orf172
KLABLALB_01557 7.51e-20 yeeC - - P - - - T5orf172
KLABLALB_01558 0.0 - - - L - - - DEAD-like helicases superfamily
KLABLALB_01559 2.16e-245 yeeA - - V - - - Type II restriction enzyme, methylase subunits
KLABLALB_01560 2.42e-222 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
KLABLALB_01561 1.21e-160 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLABLALB_01562 1.46e-213 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KLABLALB_01563 4.64e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLABLALB_01582 5.21e-226 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLABLALB_01583 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KLABLALB_01584 1.85e-199 spoVK - - O ko:K06413 - ko00000 PFAM ATPase family associated with various cellular activities (AAA)
KLABLALB_01585 7.43e-89 - - - S - - - Domain of unknown function (DUF3841)
KLABLALB_01586 1.22e-74 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
KLABLALB_01587 2.62e-133 - - - S - - - Domain of unknown function (DUF4343)
KLABLALB_01588 0.0 - - - L - - - helicase activity
KLABLALB_01589 4.53e-265 - - - K - - - DNA binding
KLABLALB_01590 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
KLABLALB_01591 8.59e-287 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
KLABLALB_01592 1.21e-212 mcrC - - V ko:K19147 - ko00000,ko02048 Psort location Cytoplasmic, score
KLABLALB_01593 0.0 mcrB - - V ko:K07452 - ko00000,ko01000,ko02048 ATPase family associated with various cellular activities (AAA)
KLABLALB_01595 8.77e-268 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLABLALB_01596 1.46e-182 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KLABLALB_01597 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLABLALB_01598 5.93e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLABLALB_01599 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLABLALB_01600 5.65e-204 camS - - S - - - sex pheromone
KLABLALB_01601 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLABLALB_01602 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KLABLALB_01603 1.13e-180 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLABLALB_01606 2.46e-14 - - - - - - - -
KLABLALB_01610 0.000162 - - - - - - - -
KLABLALB_01614 8.6e-06 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KLABLALB_01620 1.49e-11 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
KLABLALB_01624 2.48e-42 - - - L - - - four-way junction helicase activity
KLABLALB_01630 9.37e-76 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLABLALB_01631 1.81e-199 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLABLALB_01632 2.95e-284 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLABLALB_01633 2.85e-138 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLABLALB_01635 1.46e-141 csrR - - K - - - response regulator
KLABLALB_01636 9.79e-55 - - - S - - - Psort location Cytoplasmic, score
KLABLALB_01637 2.75e-206 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
KLABLALB_01638 7.09e-20 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KLABLALB_01639 3.64e-285 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KLABLALB_01640 8.44e-148 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KLABLALB_01641 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
KLABLALB_01642 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
KLABLALB_01643 6.7e-107 lysR5 - - K - - - LysR substrate binding domain
KLABLALB_01644 1.51e-71 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
KLABLALB_01645 2.9e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLABLALB_01646 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KLABLALB_01647 7.88e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KLABLALB_01648 7.55e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
KLABLALB_01649 7.95e-263 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLABLALB_01650 3.94e-46 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLABLALB_01651 3.44e-91 yqeK - - H - - - Hydrolase, HD family
KLABLALB_01652 2.79e-65 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLABLALB_01653 2.64e-103 - - - H - - - Nodulation protein S (NodS)
KLABLALB_01654 7.56e-152 ylbM - - S - - - Belongs to the UPF0348 family
KLABLALB_01655 1.58e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KLABLALB_01656 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KLABLALB_01657 5.76e-113 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KLABLALB_01658 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KLABLALB_01659 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
KLABLALB_01660 4.91e-172 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KLABLALB_01661 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLABLALB_01662 6.09e-48 - - - - - - - -
KLABLALB_01664 2.41e-163 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLABLALB_01665 3.12e-214 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLABLALB_01666 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLABLALB_01667 9.87e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLABLALB_01668 1.19e-115 epsE2 - - M - - - Bacterial sugar transferase
KLABLALB_01669 7.11e-75 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
KLABLALB_01671 3.44e-26 - - - L ko:K07482 - ko00000 Integrase
KLABLALB_01672 1.58e-25 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
KLABLALB_01676 3.25e-254 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KLABLALB_01678 8.38e-80 - - - K - - - helix_turn_helix, arabinose operon control protein
KLABLALB_01679 5.51e-69 - - - S - - - Membrane
KLABLALB_01680 2.07e-231 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KLABLALB_01681 2.34e-155 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KLABLALB_01682 1.05e-76 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KLABLALB_01683 6.64e-231 - - - L - - - Helicase C-terminal domain protein
KLABLALB_01684 1.01e-29 - - - L - - - Helicase C-terminal domain protein
KLABLALB_01685 8.4e-66 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KLABLALB_01687 1.23e-77 tnp2 - - L - - - Transposase
KLABLALB_01688 6.61e-36 - - - T - - - Putative diguanylate phosphodiesterase
KLABLALB_01689 1.53e-151 - - - T - - - diguanylate cyclase activity
KLABLALB_01690 0.0 - - - S - - - Bacterial cellulose synthase subunit
KLABLALB_01691 8.55e-256 ydaM - - M - - - Glycosyl transferase family group 2
KLABLALB_01692 4.02e-254 - - - S - - - Protein conserved in bacteria
KLABLALB_01693 7.65e-237 - - - - - - - -
KLABLALB_01694 3.21e-162 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
KLABLALB_01695 3.88e-17 - - - T - - - diguanylate cyclase
KLABLALB_01696 5.1e-18 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
KLABLALB_01697 6.47e-115 sip - - L - - - Belongs to the 'phage' integrase family
KLABLALB_01699 2.12e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
KLABLALB_01700 1.53e-149 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLABLALB_01701 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KLABLALB_01702 5.51e-171 arcT - - E - - - Cys/Met metabolism PLP-dependent enzyme
KLABLALB_01703 1.74e-75 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KLABLALB_01704 7.86e-27 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KLABLALB_01705 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
KLABLALB_01706 2.18e-168 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLABLALB_01707 6.92e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLABLALB_01708 1.8e-133 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KLABLALB_01709 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLABLALB_01710 5.58e-163 - - - - - - - -
KLABLALB_01711 2.69e-160 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KLABLALB_01712 2.94e-30 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
KLABLALB_01713 1.91e-40 - - - K - - - Bacterial regulatory proteins, tetR family
KLABLALB_01714 1.48e-129 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_01715 1.58e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KLABLALB_01716 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KLABLALB_01717 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
KLABLALB_01718 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
KLABLALB_01719 2.48e-125 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KLABLALB_01720 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KLABLALB_01721 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
KLABLALB_01722 1.5e-95 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KLABLALB_01723 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLABLALB_01724 1.48e-166 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KLABLALB_01728 1.48e-24 - - - S - - - Domain of unknown function (DUF771)
KLABLALB_01730 1.9e-38 - - - K - - - Transcriptional regulator
KLABLALB_01731 5.52e-20 - - - K - - - Helix-turn-helix XRE-family like proteins
KLABLALB_01732 4.86e-82 - - - C - - - FMN binding
KLABLALB_01733 5.31e-262 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KLABLALB_01734 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KLABLALB_01735 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KLABLALB_01737 7.43e-91 - - - L - - - Phage integrase, N-terminal SAM-like domain
KLABLALB_01741 8.17e-104 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
KLABLALB_01742 6.57e-19 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLABLALB_01743 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KLABLALB_01745 1.66e-63 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KLABLALB_01746 9.36e-51 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KLABLALB_01748 7.24e-111 - - - L - - - HNH nucleases
KLABLALB_01749 1.05e-107 - - - L - - - Phage terminase, small subunit
KLABLALB_01750 0.0 - - - S - - - Phage Terminase
KLABLALB_01752 2.17e-249 - - - S - - - Phage portal protein
KLABLALB_01753 2.82e-146 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
KLABLALB_01754 4.59e-244 - - - S - - - Phage capsid family
KLABLALB_01755 2.18e-29 - - - S - - - Phage gp6-like head-tail connector protein
KLABLALB_01756 1.18e-64 - - - S - - - Phage head-tail joining protein
KLABLALB_01757 2.67e-70 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
KLABLALB_01758 6.94e-74 - - - S - - - Protein of unknown function (DUF806)
KLABLALB_01759 4.34e-99 - - - S - - - Phage tail tube protein
KLABLALB_01760 9.54e-25 - - - S - - - Phage tail assembly chaperone proteins, TAC
KLABLALB_01762 0.0 - - - L - - - Phage tail tape measure protein TP901
KLABLALB_01763 6.21e-100 - - - S - - - Phage tail protein
KLABLALB_01764 9.2e-152 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
KLABLALB_01765 1.37e-30 - - - - - - - -
KLABLALB_01766 3.4e-90 - - - T - - - Nacht domain
KLABLALB_01767 2.97e-102 - - - T - - - Nacht domain
KLABLALB_01768 6.47e-87 - - - - - - - -
KLABLALB_01769 2.88e-225 - - - L - - - ATPase involved in DNA repair
KLABLALB_01770 4.96e-132 - - - L - - - ATPase involved in DNA repair
KLABLALB_01771 3.78e-48 - - - S ko:K19165 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
KLABLALB_01772 8.85e-76 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
KLABLALB_01773 9.57e-120 - - - O - - - Ergosterol biosynthesis ERG4/ERG24 family
KLABLALB_01774 9.15e-67 - - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
KLABLALB_01776 6.65e-89 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
KLABLALB_01777 2.97e-06 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
KLABLALB_01778 1.82e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
KLABLALB_01779 6.79e-263 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KLABLALB_01781 8.35e-141 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KLABLALB_01782 3.84e-30 - - - M - - - Glycosyl hydrolases family 25
KLABLALB_01783 1.89e-40 - - - K - - - Transcriptional regulator, MarR family
KLABLALB_01784 1.84e-217 - - - S - - - Putative peptidoglycan binding domain
KLABLALB_01786 3.06e-32 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KLABLALB_01787 1.02e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KLABLALB_01788 1.88e-174 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
KLABLALB_01789 7.01e-225 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KLABLALB_01790 2.49e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KLABLALB_01791 1.85e-06 pepF - - E - - - Peptidase family M3
KLABLALB_01792 9.33e-249 pepF - - E - - - Oligopeptidase F
KLABLALB_01793 9.44e-121 yicL - - EG - - - EamA-like transporter family
KLABLALB_01794 3.11e-90 - - - J - - - Acetyltransferase (GNAT) domain
KLABLALB_01795 1.86e-212 - - - S - - - Putative threonine/serine exporter
KLABLALB_01796 6.3e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KLABLALB_01797 1.25e-06 - - - K - - - YsiA-like protein, C-terminal region
KLABLALB_01798 1.29e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KLABLALB_01799 2.34e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KLABLALB_01800 1.25e-282 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
KLABLALB_01801 1.45e-289 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLABLALB_01802 5.01e-22 yneR - - - - - - -
KLABLALB_01803 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KLABLALB_01804 2.43e-56 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
KLABLALB_01806 1.99e-25 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
KLABLALB_01808 1.29e-79 - - - - - - - -
KLABLALB_01809 2.14e-132 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
KLABLALB_01810 6.28e-61 - - - S - - - hydrolase
KLABLALB_01811 1.77e-16 - - - S - - - hydrolase
KLABLALB_01812 6.95e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
KLABLALB_01813 4.07e-109 - - - F - - - glutamine amidotransferase
KLABLALB_01814 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
KLABLALB_01815 1.68e-54 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLABLALB_01816 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLABLALB_01819 1.8e-252 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLABLALB_01820 5.54e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KLABLALB_01821 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KLABLALB_01822 1.05e-77 - - - - - - - -
KLABLALB_01823 1.25e-275 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLABLALB_01824 5.28e-220 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KLABLALB_01825 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLABLALB_01826 3.32e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLABLALB_01827 1e-77 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
KLABLALB_01828 7.47e-219 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KLABLALB_01829 1.36e-287 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KLABLALB_01830 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLABLALB_01838 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KLABLALB_01839 7.59e-235 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLABLALB_01840 3.2e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KLABLALB_01841 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KLABLALB_01842 4.06e-150 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLABLALB_01844 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KLABLALB_01845 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLABLALB_01846 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLABLALB_01847 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLABLALB_01848 3.77e-141 - - - L - - - Initiator Replication protein
KLABLALB_01849 3.46e-46 - - - S - - - Replication initiator protein A (RepA) N-terminus
KLABLALB_01850 3.57e-157 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KLABLALB_01851 9.94e-44 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KLABLALB_01852 1.55e-110 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
KLABLALB_01853 3.71e-21 bglG - - K ko:K03488 - ko00000,ko03000 antiterminator
KLABLALB_01854 1.98e-37 - - - S - - - Phage transcriptional regulator, ArpU family
KLABLALB_01861 1.28e-57 - - - L - - - Endodeoxyribonuclease RusA
KLABLALB_01862 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
KLABLALB_01863 0.0 - - - L - - - Helicase C-terminal domain protein
KLABLALB_01864 6.1e-104 - - - - - - - -
KLABLALB_01865 6.6e-52 - - - - - - - -
KLABLALB_01866 1.71e-64 - - - - - - - -
KLABLALB_01867 5.78e-133 - - - S - - - AAA domain
KLABLALB_01868 3.44e-206 - - - D - - - AAA domain
KLABLALB_01872 6.72e-27 - - - - - - - -
KLABLALB_01873 2.13e-56 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
KLABLALB_01874 3.64e-46 - - - E - - - IrrE N-terminal-like domain
KLABLALB_01875 8.35e-37 - - - S - - - Domain of unknown function (DUF4352)
KLABLALB_01876 2.12e-39 - - - - - - - -
KLABLALB_01877 2.41e-114 - - - L - - - Phage integrase, N-terminal SAM-like domain
KLABLALB_01878 1.46e-260 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLABLALB_01879 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
KLABLALB_01880 2.84e-199 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KLABLALB_01881 6.4e-63 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
KLABLALB_01882 3.33e-97 ung2 - - L - - - Uracil-DNA glycosylase
KLABLALB_01883 6.06e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLABLALB_01884 2.04e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLABLALB_01885 5.49e-91 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KLABLALB_01886 1.61e-67 - - - S - - - Domain of unknown function (DUF956)
KLABLALB_01887 5.89e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KLABLALB_01888 1.97e-152 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KLABLALB_01889 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KLABLALB_01890 7.63e-102 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
KLABLALB_01891 2.16e-120 baeS - - T - - - Histidine kinase
KLABLALB_01892 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
KLABLALB_01893 5.17e-149 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KLABLALB_01894 4.63e-76 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KLABLALB_01895 1.29e-51 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLABLALB_01896 2.49e-43 - - - K - - - MerR HTH family regulatory protein
KLABLALB_01897 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
KLABLALB_01898 3.99e-42 - - - S - - - Domain of unknown function (DUF4811)
KLABLALB_01899 7.18e-51 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KLABLALB_01900 4.52e-77 yceE - - S - - - haloacid dehalogenase-like hydrolase
KLABLALB_01901 5.62e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KLABLALB_01902 7.26e-115 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KLABLALB_01903 2.25e-213 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
KLABLALB_01904 2.51e-126 - 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Pfam:DUF1498
KLABLALB_01905 1.2e-99 - - - G - - - Domain of unknown function (DUF4432)
KLABLALB_01906 1.43e-179 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
KLABLALB_01907 1.17e-57 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLABLALB_01908 1.2e-173 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
KLABLALB_01909 2.17e-18 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KLABLALB_01910 5.04e-128 - - - K ko:K02538 - ko00000,ko03000 PRD domain
KLABLALB_01911 1.49e-229 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
KLABLALB_01912 2.69e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KLABLALB_01913 3.54e-111 - - - S - - - Predicted membrane protein (DUF2207)
KLABLALB_01914 5.71e-28 - - - - - - - -
KLABLALB_01915 4.59e-16 epsJ2 - - S - - - Glycosyltransferase like family 2
KLABLALB_01916 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KLABLALB_01917 1.08e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
KLABLALB_01918 1.2e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
KLABLALB_01919 4.81e-230 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KLABLALB_01920 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KLABLALB_01921 1.1e-270 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KLABLALB_01922 1.88e-185 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KLABLALB_01923 5.65e-95 - - - V - - - Type I restriction modification DNA specificity domain
KLABLALB_01924 6.63e-167 - - - L - - - Belongs to the 'phage' integrase family
KLABLALB_01925 1.32e-55 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
KLABLALB_01926 2.29e-41 - - - S - - - Bacterial membrane protein YfhO
KLABLALB_01927 4.55e-20 - - - - - - - -
KLABLALB_01928 5.23e-23 - - - S - - - Psort location CytoplasmicMembrane, score
KLABLALB_01929 3.67e-43 - - - S - - - Psort location CytoplasmicMembrane, score
KLABLALB_01930 2.13e-185 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KLABLALB_01931 6.99e-66 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
KLABLALB_01932 5.89e-196 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
KLABLALB_01933 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KLABLALB_01934 3.27e-120 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KLABLALB_01935 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLABLALB_01936 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLABLALB_01937 7.22e-27 - - - L - - - COG3547 Transposase and inactivated derivatives
KLABLALB_01938 1.39e-142 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KLABLALB_01939 3.06e-159 yitL - - S ko:K00243 - ko00000 S1 domain
KLABLALB_01940 1.64e-67 - - - S - - - Protein of unknown function (DUF441)
KLABLALB_01941 8.84e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLABLALB_01942 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KLABLALB_01943 2.7e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLABLALB_01944 2.42e-76 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLABLALB_01945 6.85e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLABLALB_01946 5.56e-73 - - - - - - - -
KLABLALB_01947 4.92e-11 - - - S - - - Protein of unknown function (DUF805)
KLABLALB_01948 5.36e-07 - - - S - - - Protein of unknown function (DUF805)
KLABLALB_01949 2.76e-13 - - - S - - - Protein of unknown function (DUF805)
KLABLALB_01950 0.000912 - 2.7.11.1 - T ko:K12132 - ko00000,ko01000,ko01001 NACHT domain
KLABLALB_01951 1.73e-274 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KLABLALB_01952 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KLABLALB_01953 2.56e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
KLABLALB_01954 1.56e-225 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KLABLALB_01955 7.86e-124 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KLABLALB_01956 9.73e-90 - - - - - - - -
KLABLALB_01958 1.47e-37 - - - S - - - Cysteine-rich CPCC
KLABLALB_01960 1.47e-09 - - - M - - - LysM domain
KLABLALB_01961 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KLABLALB_01962 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
KLABLALB_01963 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KLABLALB_01970 3.37e-81 - - - H - - - Methyltransferase domain
KLABLALB_01971 6.84e-55 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
KLABLALB_01972 2.76e-52 - - - M - - - Acetyltransferase (GNAT) family
KLABLALB_01974 1.62e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
KLABLALB_01975 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
KLABLALB_01978 2.66e-106 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
KLABLALB_01979 1.8e-40 - - - S - - - CHY zinc finger
KLABLALB_01980 2.08e-52 ywnA - - K - - - Transcriptional regulator
KLABLALB_01981 8.23e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
KLABLALB_01983 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KLABLALB_01984 4.29e-96 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KLABLALB_01985 3.42e-31 yktA - - S - - - Belongs to the UPF0223 family
KLABLALB_01986 3.48e-21 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
KLABLALB_01987 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLABLALB_01988 3.51e-33 - - - - - - - -
KLABLALB_01989 3.47e-29 ykzG - - S - - - Belongs to the UPF0356 family
KLABLALB_01990 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLABLALB_01991 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLABLALB_01992 7.41e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLABLALB_01993 4.78e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLABLALB_01994 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLABLALB_01995 0.000361 - - - S - - - Tetratricopeptide repeat
KLABLALB_01996 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLABLALB_01997 1.26e-145 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLABLALB_01998 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLABLALB_01999 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KLABLALB_02000 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLABLALB_02001 5.87e-249 - - - E ko:K03294 - ko00000 amino acid
KLABLALB_02002 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KLABLALB_02003 2.25e-144 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KLABLALB_02004 3.22e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLABLALB_02005 1.99e-37 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KLABLALB_02006 7.67e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KLABLALB_02007 3.58e-175 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLABLALB_02008 1.22e-67 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLABLALB_02009 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLABLALB_02010 9.15e-187 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLABLALB_02011 8.24e-296 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KLABLALB_02012 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLABLALB_02013 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLABLALB_02014 4.4e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLABLALB_02015 3.32e-307 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLABLALB_02016 1.21e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KLABLALB_02017 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
KLABLALB_02018 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KLABLALB_02019 4.65e-50 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KLABLALB_02020 9.75e-146 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLABLALB_02021 1.37e-78 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KLABLALB_02022 3.4e-148 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KLABLALB_02023 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KLABLALB_02024 8.79e-193 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLABLALB_02025 3.13e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLABLALB_02026 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLABLALB_02027 2.16e-152 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLABLALB_02028 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLABLALB_02029 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KLABLALB_02030 2.24e-48 - - - M - - - Phosphotransferase enzyme family
KLABLALB_02031 7.2e-40 - - - M - - - Phosphotransferase enzyme family
KLABLALB_02032 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KLABLALB_02033 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KLABLALB_02034 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
KLABLALB_02035 3.25e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KLABLALB_02036 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KLABLALB_02039 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KLABLALB_02040 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KLABLALB_02041 2.79e-125 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KLABLALB_02042 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KLABLALB_02043 3.68e-17 - - - - - - - -
KLABLALB_02044 3.67e-122 - - - - - - - -
KLABLALB_02045 2.09e-16 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
KLABLALB_02046 2.87e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KLABLALB_02047 1.24e-268 yhdG - - E ko:K03294 - ko00000 Amino Acid
KLABLALB_02048 4.88e-315 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLABLALB_02049 0.0 - - - L - - - Helicase C-terminal domain protein
KLABLALB_02050 1.01e-100 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KLABLALB_02051 3.39e-232 yhdP - - S - - - Transporter associated domain
KLABLALB_02052 7.84e-33 - - - - - - - -
KLABLALB_02053 1.13e-93 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KLABLALB_02054 3.21e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KLABLALB_02055 2.78e-126 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KLABLALB_02056 1.82e-90 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLABLALB_02057 6.88e-200 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KLABLALB_02058 1.97e-174 - - - V - - - MatE
KLABLALB_02059 1.32e-57 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLABLALB_02060 5.52e-111 - - - S - - - Alpha beta hydrolase
KLABLALB_02061 1.06e-121 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLABLALB_02062 3.68e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLABLALB_02063 1.24e-137 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
KLABLALB_02064 3.5e-128 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KLABLALB_02066 1.09e-68 ccl - - S - - - QueT transporter
KLABLALB_02068 6.6e-84 - - - S - - - Uncharacterised protein, DegV family COG1307
KLABLALB_02069 2.37e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLABLALB_02070 3.11e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLABLALB_02071 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KLABLALB_02072 2.42e-109 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KLABLALB_02073 1.49e-133 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KLABLALB_02075 9.79e-65 - - - S - - - Threonine/Serine exporter, ThrE
KLABLALB_02076 9.59e-104 - - - S - - - Putative threonine/serine exporter
KLABLALB_02077 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
KLABLALB_02078 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
KLABLALB_02079 3.07e-119 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KLABLALB_02080 1.71e-27 - - - - - - - -
KLABLALB_02081 1.3e-74 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
KLABLALB_02082 4.48e-24 - - - - - - - -
KLABLALB_02083 3.45e-81 - - - I - - - alpha/beta hydrolase fold
KLABLALB_02084 2.61e-52 - - - S - - - branched-chain amino acid
KLABLALB_02085 3.58e-132 - - - E - - - AzlC protein
KLABLALB_02086 2.11e-23 - - - - - - - -
KLABLALB_02087 5.1e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KLABLALB_02088 1.25e-156 yhgE - - V ko:K01421 - ko00000 domain protein
KLABLALB_02096 2.43e-09 - - - S - - - Mor transcription activator family
KLABLALB_02097 3.27e-73 - - - K - - - WYL domain
KLABLALB_02098 5.13e-148 - - - M - - - Glycosyl hydrolases family 25
KLABLALB_02099 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KLABLALB_02100 1.86e-247 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLABLALB_02101 2.34e-188 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KLABLALB_02102 3.02e-157 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLABLALB_02103 8.86e-140 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
KLABLALB_02105 7.69e-12 - - - NU - - - MucBP domain
KLABLALB_02107 9.91e-78 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
KLABLALB_02108 7.06e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLABLALB_02110 4.09e-291 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLABLALB_02111 2.34e-104 - - - K - - - helix_turn _helix lactose operon repressor
KLABLALB_02112 2.06e-291 treC - - G - - - Psort location Cytoplasmic, score
KLABLALB_02113 4.73e-50 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KLABLALB_02114 1.68e-157 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KLABLALB_02115 7.67e-139 - - - G - - - PTS system sorbose-specific iic component
KLABLALB_02116 1.32e-84 - - - G - - - PTS system sorbose subfamily IIB component

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)