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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDHGJDOP_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDHGJDOP_00002	1.64e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDHGJDOP_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HDHGJDOP_00004	1.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDHGJDOP_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HDHGJDOP_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDHGJDOP_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDHGJDOP_00008	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00011	1.64e-224	yaaC	-	-	S	-	-	-	YaaC-like Protein
HDHGJDOP_00012	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDHGJDOP_00013	1.03e-315	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDHGJDOP_00014	7.47e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HDHGJDOP_00015	2.35e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HDHGJDOP_00016	4.16e-281	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDHGJDOP_00017	2.36e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HDHGJDOP_00019	1.4e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HDHGJDOP_00020	3.32e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HDHGJDOP_00021	8.84e-272	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HDHGJDOP_00022	4.62e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HDHGJDOP_00023	5.61e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDHGJDOP_00024	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDHGJDOP_00025	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDHGJDOP_00026	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDHGJDOP_00027	7.67e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HDHGJDOP_00028	2.16e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HDHGJDOP_00029	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00032	3.55e-39	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HDHGJDOP_00033	1.05e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HDHGJDOP_00034	6.32e-226	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HDHGJDOP_00035	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HDHGJDOP_00036	7.14e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDHGJDOP_00037	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00038	2.86e-92	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HDHGJDOP_00039	8.67e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDHGJDOP_00040	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HDHGJDOP_00041	2.53e-55	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HDHGJDOP_00042	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HDHGJDOP_00043	1.64e-62	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HDHGJDOP_00044	9.82e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDHGJDOP_00045	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HDHGJDOP_00046	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDHGJDOP_00047	1.44e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HDHGJDOP_00048	3.55e-288	yabE	-	-	T	-	-	-	protein conserved in bacteria
HDHGJDOP_00049	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDHGJDOP_00050	9.41e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDHGJDOP_00051	1.46e-186	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HDHGJDOP_00052	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00053	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HDHGJDOP_00054	2.25e-205	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDHGJDOP_00055	5.43e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HDHGJDOP_00056	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HDHGJDOP_00057	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HDHGJDOP_00058	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDHGJDOP_00059	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDHGJDOP_00060	1.4e-133	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HDHGJDOP_00061	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDHGJDOP_00062	5.24e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HDHGJDOP_00063	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDHGJDOP_00064	1.09e-116	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HDHGJDOP_00065	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_00066	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HDHGJDOP_00067	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HDHGJDOP_00068	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HDHGJDOP_00069	1.47e-128	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HDHGJDOP_00070	2.42e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HDHGJDOP_00071	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HDHGJDOP_00074	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HDHGJDOP_00075	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HDHGJDOP_00076	1.18e-229	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDHGJDOP_00077	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDHGJDOP_00078	4.29e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDHGJDOP_00079	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDHGJDOP_00080	5.46e-186	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDHGJDOP_00081	7.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDHGJDOP_00082	1.22e-192	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HDHGJDOP_00083	1.79e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDHGJDOP_00084	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDHGJDOP_00085	5.14e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HDHGJDOP_00086	3.18e-191	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HDHGJDOP_00087	1.62e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDHGJDOP_00088	1.88e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDHGJDOP_00089	4.38e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDHGJDOP_00090	9.99e-39	yazB	-	-	K	-	-	-	transcriptional
HDHGJDOP_00091	8.33e-230	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDHGJDOP_00092	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDHGJDOP_00093	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00103	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00104	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HDHGJDOP_00105	8.58e-79	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HDHGJDOP_00106	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HDHGJDOP_00107	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HDHGJDOP_00108	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDHGJDOP_00109	1.22e-247	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HDHGJDOP_00110	1.85e-245	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HDHGJDOP_00111	1.61e-156	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HDHGJDOP_00112	1.23e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HDHGJDOP_00113	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDHGJDOP_00114	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HDHGJDOP_00115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDHGJDOP_00116	9.32e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDHGJDOP_00117	9.69e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDHGJDOP_00118	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HDHGJDOP_00119	4.65e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HDHGJDOP_00120	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDHGJDOP_00121	6.9e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HDHGJDOP_00122	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDHGJDOP_00123	2.04e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDHGJDOP_00124	6.68e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDHGJDOP_00125	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDHGJDOP_00126	2.53e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HDHGJDOP_00127	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHGJDOP_00128	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHGJDOP_00129	9.87e-45	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HDHGJDOP_00130	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDHGJDOP_00131	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDHGJDOP_00132	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDHGJDOP_00133	9.55e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDHGJDOP_00134	3.62e-220	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HDHGJDOP_00135	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HDHGJDOP_00136	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDHGJDOP_00137	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HDHGJDOP_00138	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDHGJDOP_00139	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDHGJDOP_00140	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDHGJDOP_00141	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDHGJDOP_00142	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDHGJDOP_00143	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDHGJDOP_00144	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HDHGJDOP_00145	1.92e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDHGJDOP_00146	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDHGJDOP_00147	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDHGJDOP_00148	2.58e-120	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDHGJDOP_00149	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDHGJDOP_00150	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDHGJDOP_00151	1.75e-118	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDHGJDOP_00152	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDHGJDOP_00153	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDHGJDOP_00154	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HDHGJDOP_00155	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HDHGJDOP_00156	1.82e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDHGJDOP_00157	2.94e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDHGJDOP_00158	3.16e-180	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HDHGJDOP_00159	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDHGJDOP_00160	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HDHGJDOP_00161	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDHGJDOP_00162	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDHGJDOP_00163	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHGJDOP_00164	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HDHGJDOP_00165	6.9e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHGJDOP_00166	1.06e-184	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHGJDOP_00167	8.86e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHGJDOP_00168	3.42e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDHGJDOP_00169	3.79e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDHGJDOP_00170	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HDHGJDOP_00171	4.46e-179	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HDHGJDOP_00173	2.28e-99	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HDHGJDOP_00174	4.3e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_00175	4.58e-247	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HDHGJDOP_00176	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
HDHGJDOP_00177	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HDHGJDOP_00178	1.09e-174	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HDHGJDOP_00179	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00185	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00188	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00189	2.1e-270	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HDHGJDOP_00190	1.22e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDHGJDOP_00191	1.75e-227	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HDHGJDOP_00192	1.33e-254	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HDHGJDOP_00193	7.16e-284	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HDHGJDOP_00194	1.35e-216	ybaS	-	-	S	-	-	-	Na -dependent transporter
HDHGJDOP_00195	4.92e-130	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HDHGJDOP_00196	9.92e-223	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_00197	1.48e-224	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_00198	1.12e-215	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HDHGJDOP_00199	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HDHGJDOP_00200	4.44e-291	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00201	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HDHGJDOP_00202	6.18e-300	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HDHGJDOP_00203	2.44e-302	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_00204	5.23e-205	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDHGJDOP_00205	1.13e-76	ybbJ	-	-	J	-	-	-	acetyltransferase
HDHGJDOP_00206	5.95e-96	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HDHGJDOP_00212	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_00213	1.99e-145	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HDHGJDOP_00214	3.01e-186	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDHGJDOP_00215	1.1e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00216	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDHGJDOP_00217	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDHGJDOP_00218	1.17e-21	-	-	-	S	-	-	-	peptidyl-tyrosine sulfation
HDHGJDOP_00219	2.6e-220	-	-	-	O	-	-	-	growth
HDHGJDOP_00220	5.91e-68	-	-	-	S	-	-	-	ABC-2 family transporter protein
HDHGJDOP_00221	3.07e-124	ybdN	-	-	-	-	-	-	-
HDHGJDOP_00222	9.57e-165	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HDHGJDOP_00223	2.34e-203	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HDHGJDOP_00224	3.49e-134	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HDHGJDOP_00225	6.65e-66	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HDHGJDOP_00226	1.27e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_00227	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_00228	1.67e-119	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDHGJDOP_00229	6.05e-227	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
HDHGJDOP_00230	1.58e-129	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HDHGJDOP_00231	2.13e-205	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HDHGJDOP_00232	1.12e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HDHGJDOP_00233	7.69e-229	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDHGJDOP_00234	6.5e-33	-	-	-	-	-	-	-	-
HDHGJDOP_00235	1.31e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HDHGJDOP_00236	7.13e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HDHGJDOP_00237	2.99e-136	yqeB	-	-	-	-	-	-	-
HDHGJDOP_00238	2.17e-52	ybyB	-	-	-	-	-	-	-
HDHGJDOP_00239	0.0	ybeC	-	-	E	-	-	-	amino acid
HDHGJDOP_00240	1.8e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HDHGJDOP_00241	2.63e-209	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HDHGJDOP_00242	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HDHGJDOP_00243	1e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HDHGJDOP_00244	1.12e-261	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HDHGJDOP_00246	1.14e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_00247	5.91e-239	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HDHGJDOP_00248	6.7e-264	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDHGJDOP_00249	9.04e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDHGJDOP_00250	3.37e-110	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_00251	4.85e-191	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HDHGJDOP_00252	9.76e-52	ybfN	-	-	-	-	-	-	-
HDHGJDOP_00253	4.36e-240	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HDHGJDOP_00254	2.61e-266	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDHGJDOP_00255	5.77e-246	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDHGJDOP_00256	7.12e-303	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDHGJDOP_00257	4.63e-225	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HDHGJDOP_00258	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HDHGJDOP_00259	7.21e-90	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HDHGJDOP_00260	4.31e-44	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HDHGJDOP_00261	2.63e-264	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_00262	2.43e-197	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HDHGJDOP_00263	2.31e-158	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HDHGJDOP_00264	3.3e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HDHGJDOP_00265	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDHGJDOP_00266	3.53e-118	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HDHGJDOP_00267	5.44e-229	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HDHGJDOP_00268	1.89e-82	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HDHGJDOP_00269	3.11e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
HDHGJDOP_00270	4.68e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HDHGJDOP_00271	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HDHGJDOP_00272	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HDHGJDOP_00273	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDHGJDOP_00274	1.44e-155	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDHGJDOP_00275	1.99e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDHGJDOP_00276	3.41e-241	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HDHGJDOP_00277	1.47e-305	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HDHGJDOP_00278	2.53e-79	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HDHGJDOP_00279	1.19e-58	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDHGJDOP_00280	5.9e-21	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDHGJDOP_00281	1.21e-245	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HDHGJDOP_00282	6.43e-211	yccK	-	-	C	-	-	-	Aldo keto reductase
HDHGJDOP_00283	1.13e-210	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HDHGJDOP_00284	4.33e-301	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_00285	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_00286	1.31e-114	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HDHGJDOP_00287	3.74e-221	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HDHGJDOP_00288	6.52e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HDHGJDOP_00289	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HDHGJDOP_00290	1.5e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
HDHGJDOP_00291	1.86e-62	-	-	-	K	-	-	-	Virulence activator alpha C-term
HDHGJDOP_00292	5.72e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDHGJDOP_00293	1.15e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HDHGJDOP_00294	1.38e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HDHGJDOP_00295	8.68e-231	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_00296	9.56e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HDHGJDOP_00297	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HDHGJDOP_00298	3.36e-136	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HDHGJDOP_00299	4.28e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HDHGJDOP_00300	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HDHGJDOP_00301	3.9e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HDHGJDOP_00302	2.43e-265	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HDHGJDOP_00304	8.61e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HDHGJDOP_00305	2.01e-184	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HDHGJDOP_00306	4.54e-207	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HDHGJDOP_00307	6.41e-261	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HDHGJDOP_00308	2.88e-238	ycgA	-	-	S	-	-	-	Membrane
HDHGJDOP_00309	4.22e-33	ycgA	-	-	S	-	-	-	Membrane
HDHGJDOP_00310	5.14e-54	ycgB	-	-	-	-	-	-	-
HDHGJDOP_00311	2.85e-15	-	-	-	S	-	-	-	RDD family
HDHGJDOP_00312	1.55e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDHGJDOP_00313	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HDHGJDOP_00314	3.16e-97	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_00316	1.15e-54	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HDHGJDOP_00317	6.64e-76	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HDHGJDOP_00318	5.9e-183	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HDHGJDOP_00319	2.03e-305	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_00320	6.25e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HDHGJDOP_00321	2.05e-188	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDHGJDOP_00322	1.69e-164	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HDHGJDOP_00323	1.47e-121	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_00324	6.16e-148	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_00325	1.43e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDHGJDOP_00326	9.05e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HDHGJDOP_00327	8.28e-178	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HDHGJDOP_00328	1.53e-213	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HDHGJDOP_00329	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDHGJDOP_00330	1.05e-309	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDHGJDOP_00331	7.58e-286	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HDHGJDOP_00332	4.86e-235	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HDHGJDOP_00333	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HDHGJDOP_00334	1.64e-72	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HDHGJDOP_00335	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDHGJDOP_00336	1.41e-49	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HDHGJDOP_00337	9.85e-281	yciC	-	-	S	-	-	-	GTPases (G3E family)
HDHGJDOP_00338	8.75e-277	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDHGJDOP_00339	3.65e-94	yckC	-	-	S	-	-	-	membrane
HDHGJDOP_00340	7.52e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HDHGJDOP_00341	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDHGJDOP_00342	7.34e-86	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HDHGJDOP_00343	2.67e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HDHGJDOP_00344	7.04e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HDHGJDOP_00345	6.52e-132	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HDHGJDOP_00346	2.89e-84	hxlR	-	-	K	-	-	-	transcriptional
HDHGJDOP_00347	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_00348	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_00349	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HDHGJDOP_00350	1.14e-175	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HDHGJDOP_00351	5.89e-314	-	-	-	E	-	-	-	Aminotransferase class I and II
HDHGJDOP_00352	5.87e-155	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HDHGJDOP_00353	1.12e-137	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HDHGJDOP_00354	1.32e-167	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HDHGJDOP_00355	5.85e-152	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HDHGJDOP_00356	1.41e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDHGJDOP_00357	2.91e-197	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HDHGJDOP_00358	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDHGJDOP_00359	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HDHGJDOP_00360	4.77e-76	yclD	-	-	-	-	-	-	-
HDHGJDOP_00361	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HDHGJDOP_00362	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HDHGJDOP_00364	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HDHGJDOP_00365	2.66e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HDHGJDOP_00366	4.89e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HDHGJDOP_00367	2.46e-315	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_00368	2.47e-117	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDHGJDOP_00369	2.27e-176	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDHGJDOP_00370	1.22e-147	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HDHGJDOP_00371	4.6e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_00372	7.36e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HDHGJDOP_00373	1.72e-303	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HDHGJDOP_00374	1.23e-153	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDHGJDOP_00375	4.84e-300	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HDHGJDOP_00376	2.5e-162	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_00377	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HDHGJDOP_00378	4.37e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HDHGJDOP_00381	1.03e-314	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDHGJDOP_00382	1.06e-208	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_00383	1.4e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_00384	1.55e-173	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_00385	1.67e-220	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HDHGJDOP_00386	8.06e-313	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HDHGJDOP_00387	4.78e-192	ycnC	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00388	2.68e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HDHGJDOP_00389	2.79e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HDHGJDOP_00390	1.08e-67	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDHGJDOP_00391	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDHGJDOP_00392	3.02e-278	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDHGJDOP_00393	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDHGJDOP_00394	3.93e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HDHGJDOP_00395	3.14e-182	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_00396	6.58e-128	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00397	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HDHGJDOP_00398	1.15e-135	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HDHGJDOP_00399	2.18e-69	-	-	-	-	-	-	-	-
HDHGJDOP_00400	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HDHGJDOP_00401	1.96e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HDHGJDOP_00402	2.79e-255	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HDHGJDOP_00403	4.09e-78	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HDHGJDOP_00405	2.59e-175	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDHGJDOP_00406	8.23e-170	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HDHGJDOP_00407	6.98e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HDHGJDOP_00408	3.25e-181	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HDHGJDOP_00409	1.68e-168	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HDHGJDOP_00410	5.16e-226	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HDHGJDOP_00411	7.07e-162	kipR	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00412	9.77e-144	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HDHGJDOP_00414	6.7e-72	yczJ	-	-	S	-	-	-	biosynthesis
HDHGJDOP_00415	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HDHGJDOP_00416	7.28e-212	ycsN	-	-	S	-	-	-	Oxidoreductase
HDHGJDOP_00417	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HDHGJDOP_00418	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HDHGJDOP_00419	6.33e-182	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_00420	1.08e-122	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HDHGJDOP_00421	1.58e-146	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDHGJDOP_00422	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
HDHGJDOP_00423	9.89e-174	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HDHGJDOP_00424	2.67e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HDHGJDOP_00425	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HDHGJDOP_00426	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDHGJDOP_00427	7.77e-240	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDHGJDOP_00428	4.73e-183	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HDHGJDOP_00429	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HDHGJDOP_00430	1.2e-298	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HDHGJDOP_00431	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HDHGJDOP_00432	0.0	ydaO	-	-	E	-	-	-	amino acid
HDHGJDOP_00433	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDHGJDOP_00434	5.03e-80	-	-	-	K	-	-	-	acetyltransferase
HDHGJDOP_00435	1.49e-100	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HDHGJDOP_00436	6.81e-71	-	-	-	-	-	-	-	-
HDHGJDOP_00437	1.77e-235	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HDHGJDOP_00440	1.06e-53	-	-	-	-	-	-	-	-
HDHGJDOP_00441	1.47e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDHGJDOP_00444	4.61e-44	ydaT	-	-	-	-	-	-	-
HDHGJDOP_00445	6.73e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HDHGJDOP_00446	2.83e-63	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDHGJDOP_00447	6.45e-174	ydbA	-	-	P	-	-	-	EcsC protein family
HDHGJDOP_00448	8.2e-08	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HDHGJDOP_00449	1.04e-75	ydbB	-	-	G	-	-	-	Cupin domain
HDHGJDOP_00450	6.59e-76	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HDHGJDOP_00451	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HDHGJDOP_00452	8.49e-52	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HDHGJDOP_00453	2.07e-171	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HDHGJDOP_00454	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HDHGJDOP_00455	2.66e-146	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HDHGJDOP_00456	3.75e-285	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDHGJDOP_00457	1.85e-225	ydbI	-	-	S	-	-	-	AI-2E family transporter
HDHGJDOP_00458	1.79e-216	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_00459	5.5e-164	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDHGJDOP_00460	1.32e-69	ydbL	-	-	-	-	-	-	-
HDHGJDOP_00461	7.84e-256	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HDHGJDOP_00462	2.36e-17	-	-	-	S	-	-	-	Fur-regulated basic protein B
HDHGJDOP_00463	6.11e-15	-	-	-	S	-	-	-	Fur-regulated basic protein A
HDHGJDOP_00464	1.34e-158	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDHGJDOP_00465	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HDHGJDOP_00466	7.23e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDHGJDOP_00467	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDHGJDOP_00468	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDHGJDOP_00469	6.7e-93	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HDHGJDOP_00470	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HDHGJDOP_00471	8.15e-136	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HDHGJDOP_00472	4.96e-72	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDHGJDOP_00473	1.18e-230	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HDHGJDOP_00474	3.01e-274	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDHGJDOP_00475	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HDHGJDOP_00476	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDHGJDOP_00477	9.89e-176	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HDHGJDOP_00478	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HDHGJDOP_00479	5.79e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HDHGJDOP_00480	4.02e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HDHGJDOP_00481	1.34e-68	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HDHGJDOP_00482	6.83e-109	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HDHGJDOP_00483	2.67e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_00484	3.58e-135	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HDHGJDOP_00485	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HDHGJDOP_00486	1.78e-21	-	-	-	-	-	-	-	-
HDHGJDOP_00487	6.69e-104	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HDHGJDOP_00495	7.99e-71	-	-	-	-	-	-	-	-
HDHGJDOP_00496	1.19e-99	-	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00497	7.03e-123	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDHGJDOP_00498	3.05e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HDHGJDOP_00499	2.64e-143	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDHGJDOP_00500	1e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HDHGJDOP_00501	6.49e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDHGJDOP_00502	1.99e-300	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDHGJDOP_00503	3.96e-238	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HDHGJDOP_00504	1.41e-63	-	-	-	S	-	-	-	Patatin-like phospholipase
HDHGJDOP_00505	5.81e-57	-	-	-	S	-	-	-	Patatin-like phospholipase
HDHGJDOP_00507	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HDHGJDOP_00508	2.6e-90	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_00509	8.48e-196	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HDHGJDOP_00510	3.58e-201	-	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_00511	1.19e-124	yrkC	-	-	G	-	-	-	Cupin domain
HDHGJDOP_00512	1.75e-106	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HDHGJDOP_00513	1.73e-186	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HDHGJDOP_00515	1.4e-238	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HDHGJDOP_00516	7.14e-63	ydeH	-	-	-	-	-	-	-
HDHGJDOP_00517	3.65e-206	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HDHGJDOP_00518	1.96e-252	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HDHGJDOP_00519	3.59e-78	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HDHGJDOP_00520	6.33e-278	nhaC_1	-	-	C	-	-	-	antiporter
HDHGJDOP_00521	1.34e-313	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDHGJDOP_00522	1.74e-129	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_00523	1.41e-239	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HDHGJDOP_00524	2.13e-129	ydeS	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00525	2.99e-192	ydeK	-	-	EG	-	-	-	-transporter
HDHGJDOP_00526	1.8e-316	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDHGJDOP_00527	1.16e-62	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HDHGJDOP_00528	4.86e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
HDHGJDOP_00529	3.27e-277	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDHGJDOP_00530	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
HDHGJDOP_00531	4.73e-47	yraG	-	-	-	ko:K06440	-	ko00000	-
HDHGJDOP_00532	6.26e-42	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HDHGJDOP_00533	3.37e-162	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HDHGJDOP_00534	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HDHGJDOP_00535	4.32e-117	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_00536	1.37e-188	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_00537	3.1e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HDHGJDOP_00538	4.16e-263	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HDHGJDOP_00539	4.68e-280	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDHGJDOP_00540	7.19e-197	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_00541	1.05e-156	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDHGJDOP_00542	2.24e-101	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HDHGJDOP_00543	1.6e-181	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDHGJDOP_00544	3.72e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDHGJDOP_00545	1.15e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HDHGJDOP_00546	4.22e-132	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HDHGJDOP_00547	1.24e-208	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HDHGJDOP_00548	1.47e-144	ydhC	-	-	K	-	-	-	FCD
HDHGJDOP_00549	8.62e-69	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDHGJDOP_00550	1.11e-168	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDHGJDOP_00552	3.98e-311	pbpE	-	-	V	-	-	-	Beta-lactamase
HDHGJDOP_00554	5.02e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HDHGJDOP_00555	1.24e-244	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HDHGJDOP_00556	2.21e-166	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HDHGJDOP_00557	1.12e-145	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HDHGJDOP_00558	1.35e-264	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HDHGJDOP_00559	2.88e-63	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HDHGJDOP_00560	4.14e-63	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HDHGJDOP_00561	1.07e-128	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00562	0.0	ybeC	-	-	E	-	-	-	amino acid
HDHGJDOP_00563	4.74e-209	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HDHGJDOP_00564	2.82e-110	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HDHGJDOP_00565	7.98e-228	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HDHGJDOP_00566	4.86e-313	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDHGJDOP_00569	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00574	3.49e-183	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HDHGJDOP_00575	1.44e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HDHGJDOP_00576	2.69e-158	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HDHGJDOP_00577	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDHGJDOP_00578	2.83e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDHGJDOP_00579	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HDHGJDOP_00580	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HDHGJDOP_00581	1.51e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDHGJDOP_00582	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDHGJDOP_00583	2.61e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDHGJDOP_00584	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HDHGJDOP_00585	9.24e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDHGJDOP_00586	1.24e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDHGJDOP_00587	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDHGJDOP_00588	1.16e-43	-	-	-	L	-	-	-	Arm DNA-binding domain
HDHGJDOP_00589	3.68e-35	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HDHGJDOP_00590	4.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HDHGJDOP_00591	8.41e-82	-	-	-	-	-	-	-	-
HDHGJDOP_00592	3.22e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_00593	1.73e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_00594	2.39e-48	-	-	-	-	-	-	-	-
HDHGJDOP_00595	4.76e-76	-	-	-	S	-	-	-	DNA binding
HDHGJDOP_00596	3.27e-110	-	-	-	-	-	-	-	-
HDHGJDOP_00600	2.37e-98	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HDHGJDOP_00601	6.89e-72	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HDHGJDOP_00602	3.37e-162	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HDHGJDOP_00603	4.55e-36	yqaL	-	-	L	-	-	-	DnaD domain protein
HDHGJDOP_00604	1.54e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HDHGJDOP_00606	5.52e-28	-	-	-	S	-	-	-	YopX protein
HDHGJDOP_00607	1.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HDHGJDOP_00609	1.16e-23	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HDHGJDOP_00612	4.72e-217	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HDHGJDOP_00614	2.08e-54	-	-	-	S	-	-	-	dUTPase
HDHGJDOP_00617	2.62e-08	-	-	-	S	-	-	-	YopX protein
HDHGJDOP_00622	3.27e-63	-	-	-	-	-	-	-	-
HDHGJDOP_00624	1.76e-22	-	-	-	V	-	-	-	VanZ like family
HDHGJDOP_00625	5.88e-88	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HDHGJDOP_00627	1.74e-17	-	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00630	7.49e-103	yqaS	-	-	L	-	-	-	DNA packaging
HDHGJDOP_00631	9.66e-225	-	-	-	S	-	-	-	Pfam:Terminase_3C
HDHGJDOP_00632	9.32e-157	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HDHGJDOP_00633	1.53e-116	-	-	-	S	-	-	-	Phage Mu protein F like protein
HDHGJDOP_00635	3.82e-56	-	-	-	S	-	-	-	Phage minor structural protein GP20
HDHGJDOP_00636	1.85e-61	-	-	-	S	-	-	-	viral capsid
HDHGJDOP_00639	2.05e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDHGJDOP_00640	7.37e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
HDHGJDOP_00641	1.29e-49	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDHGJDOP_00642	1.14e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
HDHGJDOP_00643	3.23e-44	-	-	-	S	-	-	-	Phage tail tube protein
HDHGJDOP_00645	3.59e-186	-	-	-	-	-	-	-	-
HDHGJDOP_00647	2.51e-246	-	-	-	L	-	-	-	Phage minor structural protein
HDHGJDOP_00651	1.19e-40	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HDHGJDOP_00652	2.07e-37	xhlB	-	-	S	-	-	-	SPP1 phage holin
HDHGJDOP_00653	2e-155	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HDHGJDOP_00656	0.0	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HDHGJDOP_00658	2.21e-81	-	-	-	-	-	-	-	-
HDHGJDOP_00659	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HDHGJDOP_00660	1.55e-251	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HDHGJDOP_00661	9.02e-311	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HDHGJDOP_00662	4.48e-211	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HDHGJDOP_00663	1.47e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HDHGJDOP_00664	4.36e-143	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HDHGJDOP_00665	6.45e-222	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDHGJDOP_00666	3.97e-156	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HDHGJDOP_00667	4.64e-200	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HDHGJDOP_00668	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HDHGJDOP_00669	5.52e-184	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HDHGJDOP_00670	1.08e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_00671	7.9e-246	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HDHGJDOP_00672	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HDHGJDOP_00673	1.51e-189	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HDHGJDOP_00675	9.6e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HDHGJDOP_00676	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HDHGJDOP_00677	2.56e-307	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_00678	7.59e-180	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDHGJDOP_00679	7.99e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HDHGJDOP_00680	1e-254	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HDHGJDOP_00681	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HDHGJDOP_00682	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDHGJDOP_00683	1.44e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_00684	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HDHGJDOP_00685	1.75e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDHGJDOP_00686	6.92e-165	yebC	-	-	M	-	-	-	Membrane
HDHGJDOP_00688	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HDHGJDOP_00689	1.88e-39	yebG	-	-	S	-	-	-	NETI protein
HDHGJDOP_00690	1.87e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDHGJDOP_00691	1.15e-280	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDHGJDOP_00692	4.29e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDHGJDOP_00693	3.8e-163	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDHGJDOP_00694	2.57e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDHGJDOP_00695	4.32e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDHGJDOP_00696	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDHGJDOP_00697	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDHGJDOP_00698	2.08e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDHGJDOP_00699	1.16e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDHGJDOP_00700	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HDHGJDOP_00701	2.12e-293	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HDHGJDOP_00702	4.48e-81	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HDHGJDOP_00703	3.96e-173	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HDHGJDOP_00704	2.05e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HDHGJDOP_00705	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HDHGJDOP_00706	2.74e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HDHGJDOP_00707	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00708	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HDHGJDOP_00709	5.04e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HDHGJDOP_00710	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDHGJDOP_00711	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDHGJDOP_00712	1.59e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HDHGJDOP_00713	6.11e-231	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HDHGJDOP_00714	7.98e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HDHGJDOP_00715	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDHGJDOP_00716	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDHGJDOP_00717	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDHGJDOP_00718	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDHGJDOP_00719	1.01e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_00720	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDHGJDOP_00721	8.56e-217	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDHGJDOP_00722	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDHGJDOP_00723	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HDHGJDOP_00724	2.88e-204	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDHGJDOP_00725	3.92e-175	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HDHGJDOP_00726	5.92e-51	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HDHGJDOP_00727	2.35e-73	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HDHGJDOP_00728	2.48e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HDHGJDOP_00729	1.69e-257	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HDHGJDOP_00730	6.14e-152	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	Belongs to the WXG100 family
HDHGJDOP_00731	1.27e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HDHGJDOP_00733	2.48e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HDHGJDOP_00734	1.32e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HDHGJDOP_00735	1.34e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HDHGJDOP_00736	4.26e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HDHGJDOP_00737	1.38e-114	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDHGJDOP_00739	1.26e-147	yetF	-	-	S	-	-	-	membrane
HDHGJDOP_00740	3.06e-70	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HDHGJDOP_00741	2.87e-82	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_00742	2.4e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDHGJDOP_00743	7.84e-29	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HDHGJDOP_00744	2.59e-73	-	-	-	H	-	-	-	riboflavin kinase activity
HDHGJDOP_00745	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HDHGJDOP_00746	3.05e-110	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_00747	3.35e-246	yetM	-	-	CH	-	-	-	FAD binding domain
HDHGJDOP_00748	2.78e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HDHGJDOP_00749	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HDHGJDOP_00751	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HDHGJDOP_00752	1.4e-186	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HDHGJDOP_00753	5.59e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HDHGJDOP_00754	7.97e-222	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HDHGJDOP_00755	7.97e-273	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HDHGJDOP_00756	5.43e-227	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HDHGJDOP_00757	7.91e-271	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_00758	2.1e-306	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HDHGJDOP_00759	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDHGJDOP_00760	3.69e-165	yfmS	-	-	NT	-	-	-	chemotaxis protein
HDHGJDOP_00761	1.93e-211	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDHGJDOP_00762	4.84e-256	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHGJDOP_00763	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDHGJDOP_00764	8.36e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HDHGJDOP_00765	3.06e-249	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HDHGJDOP_00766	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDHGJDOP_00767	4.02e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HDHGJDOP_00768	3.25e-64	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HDHGJDOP_00769	1.41e-99	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HDHGJDOP_00770	9.03e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HDHGJDOP_00771	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HDHGJDOP_00772	5.26e-298	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HDHGJDOP_00773	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDHGJDOP_00780	7.92e-92	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
HDHGJDOP_00781	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HDHGJDOP_00782	4.78e-191	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HDHGJDOP_00783	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HDHGJDOP_00784	5.54e-104	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HDHGJDOP_00785	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HDHGJDOP_00786	4.96e-148	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDHGJDOP_00787	1.36e-217	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HDHGJDOP_00788	4.33e-282	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HDHGJDOP_00789	5.2e-113	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HDHGJDOP_00790	7.02e-269	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HDHGJDOP_00791	4.43e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDHGJDOP_00792	7.68e-150	yflK	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_00793	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HDHGJDOP_00794	5.69e-26	yflI	-	-	-	-	-	-	-
HDHGJDOP_00795	1.38e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HDHGJDOP_00796	1.05e-174	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HDHGJDOP_00797	9.77e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HDHGJDOP_00798	8.21e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HDHGJDOP_00799	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HDHGJDOP_00800	3.87e-80	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HDHGJDOP_00801	2.68e-100	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDHGJDOP_00802	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HDHGJDOP_00803	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HDHGJDOP_00804	1.51e-43	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_00805	3.65e-240	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_00806	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HDHGJDOP_00807	2.03e-162	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HDHGJDOP_00808	1.34e-154	frp	-	-	C	-	-	-	nitroreductase
HDHGJDOP_00809	1.06e-160	yibF	-	-	S	-	-	-	YibE/F-like protein
HDHGJDOP_00810	5.49e-235	yibE	-	-	S	-	-	-	YibE/F-like protein
HDHGJDOP_00811	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HDHGJDOP_00812	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HDHGJDOP_00813	2.99e-228	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDHGJDOP_00814	1.61e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDHGJDOP_00815	5.75e-165	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDHGJDOP_00816	1.23e-245	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_00817	7.02e-40	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HDHGJDOP_00818	1.38e-102	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDHGJDOP_00819	2.71e-63	yfkI	-	-	S	-	-	-	gas vesicle protein
HDHGJDOP_00820	8.85e-182	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HDHGJDOP_00821	1.55e-273	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_00822	3.14e-234	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HDHGJDOP_00823	4.99e-180	yfkD	-	-	S	-	-	-	YfkD-like protein
HDHGJDOP_00824	5.34e-182	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HDHGJDOP_00825	4.35e-156	yfkA	-	-	S	-	-	-	YfkB-like domain
HDHGJDOP_00826	1.77e-115	yfkA	-	-	S	-	-	-	YfkB-like domain
HDHGJDOP_00827	7.99e-37	yfjT	-	-	-	-	-	-	-
HDHGJDOP_00828	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HDHGJDOP_00829	1.52e-34	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HDHGJDOP_00830	3.36e-87	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HDHGJDOP_00832	5.27e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HDHGJDOP_00833	5.07e-201	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HDHGJDOP_00834	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDHGJDOP_00835	3.05e-93	-	-	-	O	ko:K20486	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000,ko01002	Subtilase family
HDHGJDOP_00836	4.08e-63	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDHGJDOP_00837	3.02e-220	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDHGJDOP_00838	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
HDHGJDOP_00846	1.83e-60	-	-	-	S	-	-	-	YfzA-like protein
HDHGJDOP_00847	7.85e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDHGJDOP_00848	2.86e-102	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDHGJDOP_00849	2.95e-239	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDHGJDOP_00850	4.01e-237	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDHGJDOP_00851	7.82e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDHGJDOP_00852	3.32e-302	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDHGJDOP_00853	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HDHGJDOP_00854	3.29e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HDHGJDOP_00855	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDHGJDOP_00856	3.67e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HDHGJDOP_00857	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_00858	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HDHGJDOP_00859	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDHGJDOP_00860	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HDHGJDOP_00861	7.86e-82	yfiD3	-	-	S	-	-	-	DoxX
HDHGJDOP_00862	5.91e-199	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HDHGJDOP_00863	2.12e-99	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDHGJDOP_00864	1.49e-89	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDHGJDOP_00865	1e-119	padR	-	-	K	-	-	-	transcriptional
HDHGJDOP_00866	1.83e-128	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDHGJDOP_00867	2.39e-223	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HDHGJDOP_00868	1.37e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HDHGJDOP_00869	2.04e-122	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HDHGJDOP_00870	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HDHGJDOP_00871	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
HDHGJDOP_00872	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDHGJDOP_00873	1.27e-193	yfhB	-	-	S	-	-	-	PhzF family
HDHGJDOP_00874	3.09e-133	yfhC	-	-	C	-	-	-	nitroreductase
HDHGJDOP_00875	6.01e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
HDHGJDOP_00877	3.2e-210	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HDHGJDOP_00878	1.95e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HDHGJDOP_00879	3.93e-61	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HDHGJDOP_00880	6.7e-231	yfhI	-	-	EGP	-	-	-	-transporter
HDHGJDOP_00882	6.34e-201	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HDHGJDOP_00883	1.49e-58	yfhJ	-	-	S	-	-	-	WVELL protein
HDHGJDOP_00884	2.3e-112	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HDHGJDOP_00885	3.3e-10	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HDHGJDOP_00886	1.29e-23	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HDHGJDOP_00887	8.86e-119	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HDHGJDOP_00888	1.29e-234	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHGJDOP_00889	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDHGJDOP_00890	4.29e-229	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HDHGJDOP_00891	8.93e-173	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDHGJDOP_00892	3.01e-56	-	-	-	E	-	-	-	Zn peptidase
HDHGJDOP_00893	7.33e-43	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_00894	3.24e-24	-	-	-	-	-	-	-	-
HDHGJDOP_00895	3.79e-39	-	-	-	-	-	-	-	-
HDHGJDOP_00898	1.37e-89	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HDHGJDOP_00901	8.43e-111	-	-	-	L	-	-	-	DnaD domain protein
HDHGJDOP_00902	1.06e-19	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
HDHGJDOP_00903	1.09e-210	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
HDHGJDOP_00904	1.36e-33	-	-	-	-	-	-	-	-
HDHGJDOP_00909	7.95e-37	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HDHGJDOP_00910	9.73e-103	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HDHGJDOP_00911	9.43e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HDHGJDOP_00912	1.87e-26	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HDHGJDOP_00917	1.72e-42	-	-	-	V	-	-	-	HNH nucleases
HDHGJDOP_00918	2.92e-61	-	-	-	L	-	-	-	Phage terminase, small subunit
HDHGJDOP_00919	0.0	-	-	-	S	-	-	-	Terminase
HDHGJDOP_00920	2.18e-86	-	-	-	S	-	-	-	Phage portal protein
HDHGJDOP_00921	3.12e-87	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HDHGJDOP_00922	3.41e-145	-	-	-	S	-	-	-	Phage capsid family
HDHGJDOP_00929	1.04e-65	-	-	-	S	-	-	-	Phage-related minor tail protein
HDHGJDOP_00930	3.35e-59	-	-	-	S	-	-	-	Phage tail protein
HDHGJDOP_00931	2.45e-26	-	-	-	S	-	-	-	Prophage endopeptidase tail
HDHGJDOP_00933	2.7e-128	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDHGJDOP_00934	3.24e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDHGJDOP_00937	4.67e-29	bhlA	-	-	S	-	-	-	BhlA holin family
HDHGJDOP_00938	1.99e-33	xhlB	-	-	S	-	-	-	SPP1 phage holin
HDHGJDOP_00939	5.67e-84	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_00942	3.07e-90	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HDHGJDOP_00943	8.53e-13	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HDHGJDOP_00944	3.84e-258	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HDHGJDOP_00945	1.47e-49	yfhS	-	-	-	-	-	-	-
HDHGJDOP_00946	1.73e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_00947	9.58e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HDHGJDOP_00948	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HDHGJDOP_00949	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HDHGJDOP_00950	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HDHGJDOP_00951	1.76e-237	ygaE	-	-	S	-	-	-	Membrane
HDHGJDOP_00952	1.27e-309	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HDHGJDOP_00953	7.73e-109	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HDHGJDOP_00954	6.8e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDHGJDOP_00955	1.1e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
HDHGJDOP_00956	2.08e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HDHGJDOP_00957	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_00975	4.7e-126	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDHGJDOP_00978	2.12e-50	-	-	-	S	-	-	-	Helix-turn-helix domain
HDHGJDOP_00979	6.51e-51	-	-	-	-	-	-	-	-
HDHGJDOP_00984	5.63e-21	-	-	-	-	-	-	-	-
HDHGJDOP_00985	9.9e-78	-	-	-	-	-	-	-	-
HDHGJDOP_00988	5.15e-138	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
HDHGJDOP_00991	3.73e-175	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HDHGJDOP_00992	3.87e-164	-	-	-	L	-	-	-	Toprim-like
HDHGJDOP_00999	1.4e-103	-	-	-	-	-	-	-	-
HDHGJDOP_01000	1.77e-62	-	-	-	-	-	-	-	-
HDHGJDOP_01001	6.45e-25	-	-	-	-	-	-	-	-
HDHGJDOP_01003	0.0	-	-	-	L	-	-	-	3'-5' exonuclease
HDHGJDOP_01005	1.09e-204	-	-	-	-	-	-	-	-
HDHGJDOP_01006	1.91e-33	-	-	-	-	-	-	-	-
HDHGJDOP_01011	1.87e-54	-	-	-	F	-	-	-	Belongs to the NrdI family
HDHGJDOP_01012	2.78e-151	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHGJDOP_01013	7.15e-05	-	-	-	S	-	-	-	Transcriptional regulator
HDHGJDOP_01014	1.19e-227	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHGJDOP_01016	1.27e-193	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHGJDOP_01018	3.31e-87	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
HDHGJDOP_01021	2.13e-129	-	2.1.1.148	-	F	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HDHGJDOP_01022	6.78e-44	-	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01023	2.2e-82	-	-	-	S	-	-	-	SprT-like family
HDHGJDOP_01024	8.04e-51	-	-	-	-	-	-	-	-
HDHGJDOP_01025	4.6e-77	-	-	-	H	-	-	-	dephospho-CoA kinase activity
HDHGJDOP_01026	1.22e-211	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HDHGJDOP_01028	3.3e-63	-	-	-	K	-	-	-	Sigma-70, region 4
HDHGJDOP_01029	1.58e-65	-	-	-	-	-	-	-	-
HDHGJDOP_01030	3.73e-172	-	-	-	-	-	-	-	-
HDHGJDOP_01032	3.64e-151	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HDHGJDOP_01034	7.61e-32	-	-	-	-	-	-	-	-
HDHGJDOP_01035	6.54e-61	-	-	-	-	-	-	-	-
HDHGJDOP_01039	1.34e-14	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDHGJDOP_01040	4.53e-99	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HDHGJDOP_01041	1.61e-24	-	-	-	-	-	-	-	-
HDHGJDOP_01044	2.65e-09	-	-	-	-	-	-	-	-
HDHGJDOP_01045	1.12e-86	-	-	-	L	-	-	-	Phage integrase family
HDHGJDOP_01046	0.0	-	-	-	S	-	-	-	TIGRFAM Phage
HDHGJDOP_01047	6.16e-35	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
HDHGJDOP_01048	6.42e-202	-	-	-	-	-	-	-	-
HDHGJDOP_01049	4.13e-101	-	-	-	S	-	-	-	Phage minor capsid protein 2
HDHGJDOP_01050	3.57e-32	-	-	-	-	-	-	-	-
HDHGJDOP_01051	3.56e-187	-	-	-	S	-	-	-	Family of unknown function (DUF5309)
HDHGJDOP_01054	3.72e-34	-	-	-	-	-	-	-	-
HDHGJDOP_01057	9.4e-61	-	-	-	N	-	-	-	domain, Protein
HDHGJDOP_01060	1.09e-49	-	-	-	D	-	-	-	phage tail tape measure protein
HDHGJDOP_01061	3.68e-153	-	-	-	D	-	-	-	phage tail tape measure protein
HDHGJDOP_01062	4.16e-66	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HDHGJDOP_01063	6.29e-91	-	-	-	L	-	-	-	Prophage endopeptidase tail
HDHGJDOP_01064	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HDHGJDOP_01065	2.47e-104	-	-	-	-	-	-	-	-
HDHGJDOP_01068	1.66e-39	-	-	-	S	-	-	-	BhlA holin family
HDHGJDOP_01069	7.04e-186	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HDHGJDOP_01070	1.04e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HDHGJDOP_01074	4.25e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HDHGJDOP_01076	2.25e-311	-	-	-	C	-	-	-	Na+/H+ antiporter family
HDHGJDOP_01077	2.28e-156	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HDHGJDOP_01078	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDHGJDOP_01079	3.15e-313	ygaK	-	-	C	-	-	-	Berberine and berberine like
HDHGJDOP_01081	1.69e-291	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HDHGJDOP_01082	2.33e-185	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDHGJDOP_01083	6.2e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01084	5.45e-170	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01085	5.17e-165	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01086	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HDHGJDOP_01087	2.39e-227	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HDHGJDOP_01088	1.02e-176	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HDHGJDOP_01089	5.5e-217	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HDHGJDOP_01090	6.5e-183	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HDHGJDOP_01091	5.74e-266	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HDHGJDOP_01093	1.62e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDHGJDOP_01094	2.4e-102	ygaO	-	-	-	-	-	-	-
HDHGJDOP_01095	5.45e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01097	1.34e-138	yhzB	-	-	S	-	-	-	B3/4 domain
HDHGJDOP_01098	2.14e-280	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDHGJDOP_01099	8.37e-216	yhbB	-	-	S	-	-	-	Putative amidase domain
HDHGJDOP_01100	2.31e-110	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDHGJDOP_01101	3.35e-132	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HDHGJDOP_01102	2.51e-76	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HDHGJDOP_01103	7.48e-85	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HDHGJDOP_01104	4.51e-08	-	-	-	-	-	-	-	-
HDHGJDOP_01105	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HDHGJDOP_01106	1.74e-275	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HDHGJDOP_01107	5.43e-94	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HDHGJDOP_01108	2.98e-130	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HDHGJDOP_01109	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HDHGJDOP_01110	2.61e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDHGJDOP_01111	1.03e-65	yhcC	-	-	-	-	-	-	-
HDHGJDOP_01112	7.54e-65	-	-	-	-	-	-	-	-
HDHGJDOP_01113	3.06e-77	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01114	8.89e-147	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_01115	3.74e-212	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_01116	1.87e-201	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDHGJDOP_01117	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HDHGJDOP_01118	6.9e-161	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDHGJDOP_01119	2.76e-230	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HDHGJDOP_01120	1.01e-290	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDHGJDOP_01121	1.79e-49	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HDHGJDOP_01122	5.08e-60	yhcM	-	-	-	-	-	-	-
HDHGJDOP_01123	6.26e-101	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_01124	3.99e-199	yhcP	-	-	-	-	-	-	-
HDHGJDOP_01125	2.2e-149	yhcQ	-	-	M	-	-	-	Spore coat protein
HDHGJDOP_01126	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDHGJDOP_01127	3.17e-128	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HDHGJDOP_01128	2.24e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDHGJDOP_01129	1.88e-83	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HDHGJDOP_01130	5.88e-89	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HDHGJDOP_01131	1.33e-158	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HDHGJDOP_01132	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDHGJDOP_01133	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDHGJDOP_01134	2.26e-129	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HDHGJDOP_01135	2.6e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDHGJDOP_01136	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDHGJDOP_01137	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HDHGJDOP_01138	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HDHGJDOP_01139	2.73e-247	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_01140	5.61e-139	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDHGJDOP_01141	2.89e-108	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HDHGJDOP_01142	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HDHGJDOP_01143	2.33e-68	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HDHGJDOP_01144	1.69e-282	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HDHGJDOP_01145	1.49e-93	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HDHGJDOP_01146	5.72e-314	ygxB	-	-	M	-	-	-	Conserved TM helix
HDHGJDOP_01147	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HDHGJDOP_01148	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HDHGJDOP_01149	2.28e-166	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HDHGJDOP_01150	1.7e-201	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01151	2.19e-250	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HDHGJDOP_01152	3.42e-200	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_01153	1.1e-311	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HDHGJDOP_01154	4.63e-264	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDHGJDOP_01155	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HDHGJDOP_01156	2.03e-249	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HDHGJDOP_01157	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_01158	4.04e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDHGJDOP_01159	2.66e-305	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HDHGJDOP_01160	2.3e-91	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HDHGJDOP_01161	9.37e-276	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDHGJDOP_01162	7.35e-290	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDHGJDOP_01163	5.48e-314	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HDHGJDOP_01164	1.68e-69	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDHGJDOP_01165	4.22e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDHGJDOP_01166	1.26e-156	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HDHGJDOP_01167	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HDHGJDOP_01168	5.39e-252	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HDHGJDOP_01169	3.53e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDHGJDOP_01170	6.85e-192	nodB1	-	-	G	-	-	-	deacetylase
HDHGJDOP_01171	1.05e-191	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HDHGJDOP_01172	9.13e-126	pksA	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_01173	1.17e-118	ymcC	-	-	S	-	-	-	Membrane
HDHGJDOP_01174	3.96e-107	-	-	-	T	-	-	-	universal stress protein
HDHGJDOP_01175	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HDHGJDOP_01176	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HDHGJDOP_01177	9.64e-127	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HDHGJDOP_01179	1.91e-38	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HDHGJDOP_01180	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HDHGJDOP_01181	5.52e-316	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HDHGJDOP_01182	2.7e-257	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HDHGJDOP_01183	3.13e-254	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HDHGJDOP_01184	5.48e-69	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HDHGJDOP_01185	2.49e-197	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDHGJDOP_01186	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HDHGJDOP_01187	1.48e-311	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HDHGJDOP_01188	9.07e-263	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HDHGJDOP_01189	6.25e-112	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HDHGJDOP_01191	4.59e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HDHGJDOP_01192	1.21e-20	-	-	-	S	-	-	-	YhzD-like protein
HDHGJDOP_01193	3.45e-209	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_01194	2.67e-274	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HDHGJDOP_01195	2.2e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HDHGJDOP_01196	0.0	yhaN	-	-	L	-	-	-	AAA domain
HDHGJDOP_01197	3.38e-224	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HDHGJDOP_01198	8.23e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HDHGJDOP_01199	3.2e-182	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDHGJDOP_01200	4.32e-122	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HDHGJDOP_01201	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HDHGJDOP_01202	1.07e-142	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HDHGJDOP_01203	1.58e-53	yhaH	-	-	S	-	-	-	YtxH-like protein
HDHGJDOP_01204	2.55e-24	-	-	-	-	-	-	-	-
HDHGJDOP_01205	1.12e-97	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HDHGJDOP_01206	1.49e-252	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDHGJDOP_01207	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HDHGJDOP_01208	2.13e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HDHGJDOP_01209	3.4e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDHGJDOP_01210	9.96e-152	ecsC	-	-	S	-	-	-	EcsC protein family
HDHGJDOP_01211	1.68e-274	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDHGJDOP_01212	1.65e-303	yhfA	-	-	C	-	-	-	membrane
HDHGJDOP_01213	2.98e-115	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HDHGJDOP_01214	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDHGJDOP_01215	9.19e-253	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HDHGJDOP_01216	3.4e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HDHGJDOP_01217	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HDHGJDOP_01218	5.15e-130	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01219	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HDHGJDOP_01220	2.04e-226	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDHGJDOP_01222	1.66e-247	yhfE	-	-	G	-	-	-	peptidase M42
HDHGJDOP_01223	3.75e-286	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDHGJDOP_01224	2.4e-173	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HDHGJDOP_01225	1.07e-240	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HDHGJDOP_01226	3.92e-137	yhfK	-	-	GM	-	-	-	NmrA-like family
HDHGJDOP_01227	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HDHGJDOP_01228	9.31e-84	yhfM	-	-	-	-	-	-	-
HDHGJDOP_01229	1.33e-293	yhfN	-	-	O	-	-	-	Peptidase M48
HDHGJDOP_01230	1.24e-258	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDHGJDOP_01231	1.78e-163	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HDHGJDOP_01232	4.57e-129	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HDHGJDOP_01233	8.49e-245	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HDHGJDOP_01234	1.98e-302	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HDHGJDOP_01235	2.32e-110	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDHGJDOP_01236	3.11e-167	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HDHGJDOP_01237	5.89e-68	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HDHGJDOP_01238	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HDHGJDOP_01239	2.73e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_01240	5.49e-42	yhzC	-	-	S	-	-	-	IDEAL
HDHGJDOP_01241	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HDHGJDOP_01242	4.21e-74	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HDHGJDOP_01243	1.28e-213	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
HDHGJDOP_01244	1.53e-156	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HDHGJDOP_01245	7.11e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HDHGJDOP_01246	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HDHGJDOP_01247	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDHGJDOP_01248	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HDHGJDOP_01249	2.3e-76	yhjD	-	-	-	-	-	-	-
HDHGJDOP_01250	8.02e-136	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_01251	1.3e-116	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDHGJDOP_01252	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HDHGJDOP_01253	9.88e-120	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_01254	2.03e-254	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HDHGJDOP_01255	1.56e-260	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_01256	1.24e-138	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HDHGJDOP_01257	3.47e-108	yhjR	-	-	S	-	-	-	Rubrerythrin
HDHGJDOP_01258	8.81e-152	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_01259	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HDHGJDOP_01260	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDHGJDOP_01261	7.47e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDHGJDOP_01262	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HDHGJDOP_01263	3.36e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HDHGJDOP_01264	5.49e-42	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HDHGJDOP_01265	2.37e-77	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HDHGJDOP_01266	1.44e-31	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HDHGJDOP_01267	3.28e-104	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HDHGJDOP_01268	5.87e-44	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HDHGJDOP_01269	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HDHGJDOP_01270	2.45e-13	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HDHGJDOP_01271	2.25e-211	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HDHGJDOP_01272	4.48e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HDHGJDOP_01273	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDHGJDOP_01274	5.25e-115	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HDHGJDOP_01275	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDHGJDOP_01276	6.09e-150	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HDHGJDOP_01277	1.69e-307	yisQ	-	-	V	-	-	-	Mate efflux family protein
HDHGJDOP_01278	1.77e-201	yisR	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_01279	3.87e-179	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDHGJDOP_01280	2.32e-195	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HDHGJDOP_01281	3.26e-100	yisT	-	-	S	-	-	-	DinB family
HDHGJDOP_01282	8.48e-96	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HDHGJDOP_01283	1.72e-232	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDHGJDOP_01284	9.1e-82	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HDHGJDOP_01285	6.78e-100	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_01286	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDHGJDOP_01287	7.44e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HDHGJDOP_01288	3.3e-199	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HDHGJDOP_01289	2.3e-186	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HDHGJDOP_01290	1.06e-288	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HDHGJDOP_01291	4.22e-293	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HDHGJDOP_01292	8.05e-196	yitS	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01293	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_01294	3.05e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HDHGJDOP_01295	4.3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HDHGJDOP_01296	1.49e-11	-	-	-	-	-	-	-	-
HDHGJDOP_01297	3.84e-192	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDHGJDOP_01298	1.98e-182	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDHGJDOP_01299	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HDHGJDOP_01300	3.29e-92	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HDHGJDOP_01301	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HDHGJDOP_01302	4.44e-117	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HDHGJDOP_01303	1.26e-246	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDHGJDOP_01304	4.35e-282	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDHGJDOP_01305	3.58e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDHGJDOP_01306	5.32e-266	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HDHGJDOP_01307	4.59e-248	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDHGJDOP_01308	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HDHGJDOP_01309	1.78e-220	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDHGJDOP_01310	2.07e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
HDHGJDOP_01311	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDHGJDOP_01312	6.59e-171	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HDHGJDOP_01313	7.04e-127	yjaV	-	-	-	-	-	-	-
HDHGJDOP_01314	8.66e-209	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HDHGJDOP_01315	3.74e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HDHGJDOP_01316	1.46e-37	yjzB	-	-	-	-	-	-	-
HDHGJDOP_01317	1.26e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDHGJDOP_01318	1.24e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDHGJDOP_01319	2.47e-179	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HDHGJDOP_01320	1.81e-226	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01321	4.48e-232	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01322	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HDHGJDOP_01323	8.55e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01324	7.81e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01325	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HDHGJDOP_01326	8.74e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HDHGJDOP_01327	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDHGJDOP_01328	2.08e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01329	1.46e-209	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01330	1.96e-252	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01331	2.02e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01332	3.04e-280	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HDHGJDOP_01333	1.04e-130	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDHGJDOP_01334	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDHGJDOP_01335	2.28e-140	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HDHGJDOP_01336	2.3e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDHGJDOP_01337	1.14e-256	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDHGJDOP_01338	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HDHGJDOP_01339	3.14e-27	-	-	-	-	-	-	-	-
HDHGJDOP_01340	9.23e-215	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HDHGJDOP_01341	6.79e-91	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HDHGJDOP_01342	1.15e-138	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDHGJDOP_01343	8.1e-118	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01344	3.37e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HDHGJDOP_01345	3.67e-138	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HDHGJDOP_01346	6.92e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDHGJDOP_01347	2.7e-201	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDHGJDOP_01348	1.1e-176	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HDHGJDOP_01349	1.5e-108	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDHGJDOP_01350	2.06e-170	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HDHGJDOP_01351	2.91e-132	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HDHGJDOP_01352	8.33e-255	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HDHGJDOP_01353	5.3e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HDHGJDOP_01354	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HDHGJDOP_01355	7.09e-228	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDHGJDOP_01356	2.99e-180	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDHGJDOP_01357	1.38e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HDHGJDOP_01358	2.47e-100	yjbX	-	-	S	-	-	-	Spore coat protein
HDHGJDOP_01359	3.35e-105	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HDHGJDOP_01360	1.75e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HDHGJDOP_01361	3.55e-98	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HDHGJDOP_01362	1.02e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
HDHGJDOP_01363	9.4e-45	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HDHGJDOP_01364	1.69e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HDHGJDOP_01367	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HDHGJDOP_01368	1.05e-50	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HDHGJDOP_01369	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDHGJDOP_01370	1.62e-44	-	-	-	-	-	-	-	-
HDHGJDOP_01371	6.53e-167	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HDHGJDOP_01372	2e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDHGJDOP_01373	1.09e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDHGJDOP_01374	1.19e-45	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HDHGJDOP_01375	6.83e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDHGJDOP_01376	6.7e-119	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HDHGJDOP_01377	1.79e-157	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HDHGJDOP_01378	3.46e-265	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDHGJDOP_01379	5.84e-273	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDHGJDOP_01381	2.89e-73	-	-	-	-	-	-	-	-
HDHGJDOP_01382	2.31e-90	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HDHGJDOP_01383	1.06e-42	-	-	-	-	-	-	-	-
HDHGJDOP_01384	3.75e-116	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HDHGJDOP_01385	1.61e-128	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase
HDHGJDOP_01386	2.21e-28	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HDHGJDOP_01387	9.5e-81	-	-	-	H	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_01389	7.99e-240	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDHGJDOP_01390	2.8e-119	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDHGJDOP_01391	3.84e-226	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HDHGJDOP_01392	9.18e-49	-	-	-	S	-	-	-	YolD-like protein
HDHGJDOP_01393	2.46e-57	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDHGJDOP_01394	4.74e-38	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HDHGJDOP_01398	0.000667	KLHL36	-	-	T	ko:K13958	-	ko00000,ko04121	protein modification by small protein conjugation
HDHGJDOP_01399	4.57e-21	-	-	-	N	-	-	-	Kelch motif
HDHGJDOP_01401	3.78e-196	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HDHGJDOP_01402	7.1e-58	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HDHGJDOP_01403	5.5e-302	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HDHGJDOP_01404	1.09e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_01405	7.71e-277	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HDHGJDOP_01406	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHGJDOP_01407	3.63e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_01408	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDHGJDOP_01409	1.39e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HDHGJDOP_01410	1.67e-151	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDHGJDOP_01411	3.81e-45	-	-	-	-	-	-	-	-
HDHGJDOP_01412	4.16e-69	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_01413	2.77e-133	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HDHGJDOP_01415	1.07e-28	yjfB	-	-	S	-	-	-	Putative motility protein
HDHGJDOP_01416	6.25e-83	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HDHGJDOP_01417	4.05e-122	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HDHGJDOP_01418	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HDHGJDOP_01419	3.47e-150	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HDHGJDOP_01420	1.44e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HDHGJDOP_01421	1.73e-40	-	-	-	-	-	-	-	-
HDHGJDOP_01422	3.96e-275	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDHGJDOP_01423	7.68e-274	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HDHGJDOP_01424	5.21e-88	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HDHGJDOP_01425	4.85e-98	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HDHGJDOP_01426	1.44e-65	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HDHGJDOP_01427	4.94e-42	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01428	5.99e-220	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HDHGJDOP_01429	1.47e-110	yjlB	-	-	S	-	-	-	Cupin domain
HDHGJDOP_01430	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HDHGJDOP_01431	8.37e-278	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDHGJDOP_01432	2.92e-80	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HDHGJDOP_01433	1.62e-231	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HDHGJDOP_01434	3.18e-203	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HDHGJDOP_01435	1.29e-112	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HDHGJDOP_01436	2.12e-165	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HDHGJDOP_01438	7.24e-164	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDHGJDOP_01439	9.4e-100	yjoA	-	-	S	-	-	-	DinB family
HDHGJDOP_01440	3.13e-274	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HDHGJDOP_01442	5.72e-213	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HDHGJDOP_01443	3.19e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
HDHGJDOP_01444	2.69e-128	yjqB	-	-	S	-	-	-	phage-related replication protein
HDHGJDOP_01445	2.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HDHGJDOP_01446	1.27e-72	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_01448	8.33e-185	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HDHGJDOP_01452	3.15e-105	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HDHGJDOP_01453	1.37e-139	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HDHGJDOP_01454	3.35e-263	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HDHGJDOP_01455	1.72e-302	xkdE3	-	-	S	-	-	-	portal protein
HDHGJDOP_01456	8.47e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HDHGJDOP_01457	3.38e-202	xkdG	-	-	S	-	-	-	Phage capsid family
HDHGJDOP_01459	2.41e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDHGJDOP_01460	1.82e-75	xkdJ	-	-	-	-	-	-	-
HDHGJDOP_01461	3.86e-21	-	-	-	-	-	-	-	-
HDHGJDOP_01462	4.44e-285	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HDHGJDOP_01463	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HDHGJDOP_01464	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HDHGJDOP_01465	4.33e-27	-	-	-	-	-	-	-	-
HDHGJDOP_01466	6.59e-83	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HDHGJDOP_01467	1.33e-252	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HDHGJDOP_01468	1.88e-144	xkdP	-	-	S	-	-	-	Lysin motif
HDHGJDOP_01469	2.78e-208	xkdQ	-	-	G	-	-	-	NLP P60 protein
HDHGJDOP_01470	3.05e-44	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HDHGJDOP_01471	2.35e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HDHGJDOP_01472	7.44e-208	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HDHGJDOP_01473	3.37e-111	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HDHGJDOP_01474	1.48e-36	-	-	-	-	-	-	-	-
HDHGJDOP_01475	1.04e-194	-	-	-	-	-	-	-	-
HDHGJDOP_01477	1.05e-36	xkdX	-	-	-	-	-	-	-
HDHGJDOP_01478	2.97e-167	xepA	-	-	-	-	-	-	-
HDHGJDOP_01479	6.44e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HDHGJDOP_01480	2.62e-49	xhlB	-	-	S	-	-	-	SPP1 phage holin
HDHGJDOP_01481	2.43e-206	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_01482	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HDHGJDOP_01483	1.05e-169	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HDHGJDOP_01484	2.36e-224	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HDHGJDOP_01485	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HDHGJDOP_01486	2.11e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HDHGJDOP_01487	1.75e-227	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HDHGJDOP_01488	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDHGJDOP_01489	3.02e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHGJDOP_01491	2.08e-266	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDHGJDOP_01492	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HDHGJDOP_01493	4.18e-198	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HDHGJDOP_01494	2.68e-202	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01495	3.22e-218	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDHGJDOP_01496	1.49e-230	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01497	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDHGJDOP_01498	8.59e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HDHGJDOP_01499	2e-244	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HDHGJDOP_01500	1.74e-198	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDHGJDOP_01501	1.49e-227	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_01502	6.11e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HDHGJDOP_01503	1.45e-179	ykgA	-	-	E	-	-	-	Amidinotransferase
HDHGJDOP_01504	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HDHGJDOP_01505	1.01e-118	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDHGJDOP_01506	8.24e-64	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HDHGJDOP_01507	1.22e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HDHGJDOP_01508	1.03e-211	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HDHGJDOP_01509	3.28e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDHGJDOP_01510	1.35e-281	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDHGJDOP_01511	1.89e-90	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HDHGJDOP_01512	6.88e-102	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HDHGJDOP_01513	1.3e-90	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HDHGJDOP_01514	1.46e-70	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HDHGJDOP_01516	2.15e-260	-	-	-	M	-	-	-	Glycosyl transferase family 2
HDHGJDOP_01517	8.96e-151	-	-	-	K	-	-	-	Collagen triple helix repeat
HDHGJDOP_01518	5.93e-263	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_01519	7.17e-152	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HDHGJDOP_01520	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDHGJDOP_01521	2.76e-221	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDHGJDOP_01522	2.08e-179	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDHGJDOP_01523	7.49e-161	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HDHGJDOP_01524	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_01525	3.67e-123	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HDHGJDOP_01526	4.54e-303	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HDHGJDOP_01528	7.93e-306	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HDHGJDOP_01529	3.53e-69	tnrA	-	-	K	-	-	-	transcriptional
HDHGJDOP_01530	2.24e-23	-	-	-	-	-	-	-	-
HDHGJDOP_01531	3.57e-35	ykoL	-	-	-	-	-	-	-
HDHGJDOP_01532	3.16e-104	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HDHGJDOP_01533	2.57e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HDHGJDOP_01534	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HDHGJDOP_01535	1.82e-197	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HDHGJDOP_01536	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HDHGJDOP_01537	1.21e-123	ykoX	-	-	S	-	-	-	membrane-associated protein
HDHGJDOP_01538	5.75e-164	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HDHGJDOP_01539	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_01540	3.51e-221	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HDHGJDOP_01541	3.31e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HDHGJDOP_01542	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HDHGJDOP_01543	1.74e-197	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HDHGJDOP_01544	7.83e-301	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HDHGJDOP_01545	2.76e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_01546	1.37e-26	ykzE	-	-	-	-	-	-	-
HDHGJDOP_01547	1.59e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HDHGJDOP_01548	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_01549	9.18e-105	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDHGJDOP_01551	1.59e-244	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HDHGJDOP_01552	9.79e-278	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HDHGJDOP_01553	1.03e-175	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDHGJDOP_01554	1.52e-283	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDHGJDOP_01555	4.16e-284	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HDHGJDOP_01556	1.45e-169	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HDHGJDOP_01557	1.15e-140	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HDHGJDOP_01558	7.7e-117	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HDHGJDOP_01560	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HDHGJDOP_01561	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HDHGJDOP_01562	2.49e-160	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HDHGJDOP_01563	2.96e-176	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HDHGJDOP_01564	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HDHGJDOP_01565	6.18e-222	ykvI	-	-	S	-	-	-	membrane
HDHGJDOP_01567	1.81e-196	-	-	-	-	-	-	-	-
HDHGJDOP_01568	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDHGJDOP_01569	2.55e-102	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HDHGJDOP_01570	1.98e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HDHGJDOP_01571	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HDHGJDOP_01572	6.76e-56	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HDHGJDOP_01573	1.56e-34	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01574	8.76e-38	-	-	-	-	-	-	-	-
HDHGJDOP_01575	2.13e-135	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HDHGJDOP_01576	1.16e-300	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_01577	1.04e-105	stoA	-	-	CO	-	-	-	thiol-disulfide
HDHGJDOP_01578	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HDHGJDOP_01579	1.51e-259	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HDHGJDOP_01581	4.21e-217	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_01582	1.54e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HDHGJDOP_01583	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_01584	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HDHGJDOP_01585	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDHGJDOP_01586	1.22e-48	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01587	2.29e-252	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HDHGJDOP_01588	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HDHGJDOP_01589	5.71e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HDHGJDOP_01590	9.19e-65	-	-	-	-	-	-	-	-
HDHGJDOP_01591	1.7e-167	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HDHGJDOP_01592	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDHGJDOP_01593	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_01594	5.43e-274	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDHGJDOP_01595	2.22e-15	-	-	-	-	-	-	-	-
HDHGJDOP_01596	1.3e-211	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HDHGJDOP_01597	1.45e-107	ykyB	-	-	S	-	-	-	YkyB-like protein
HDHGJDOP_01598	2e-302	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_01599	3.48e-114	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01600	7.29e-188	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HDHGJDOP_01601	1.33e-175	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_01603	5e-293	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HDHGJDOP_01604	2.11e-49	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01605	6.94e-117	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HDHGJDOP_01606	2.63e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HDHGJDOP_01607	7.03e-98	ykuL	-	-	S	-	-	-	CBS domain
HDHGJDOP_01608	1.08e-214	ccpC	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_01609	2.92e-113	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDHGJDOP_01610	1.07e-207	ykuO	-	-	-	-	-	-	-
HDHGJDOP_01611	2.61e-95	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDHGJDOP_01612	4.79e-128	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDHGJDOP_01613	8.58e-271	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDHGJDOP_01614	1.25e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HDHGJDOP_01615	5.77e-177	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HDHGJDOP_01617	7.8e-23	ykuV	-	-	CO	-	-	-	thiol-disulfide
HDHGJDOP_01618	1.14e-58	ykuV	-	-	CO	-	-	-	thiol-disulfide
HDHGJDOP_01620	3.55e-125	rok	-	-	K	-	-	-	Repressor of ComK
HDHGJDOP_01621	8.39e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
HDHGJDOP_01622	3.85e-130	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HDHGJDOP_01623	1.45e-233	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDHGJDOP_01624	7.3e-305	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HDHGJDOP_01625	3.06e-111	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HDHGJDOP_01626	1.19e-107	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HDHGJDOP_01627	4.7e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HDHGJDOP_01628	5.77e-134	yknW	-	-	S	-	-	-	Yip1 domain
HDHGJDOP_01629	7e-224	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDHGJDOP_01630	3.39e-157	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_01631	4.52e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HDHGJDOP_01632	8.9e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01633	8.8e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HDHGJDOP_01634	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HDHGJDOP_01635	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDHGJDOP_01636	3.54e-48	ykoA	-	-	-	-	-	-	-
HDHGJDOP_01637	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDHGJDOP_01638	4.63e-200	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDHGJDOP_01639	1.63e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HDHGJDOP_01640	7.7e-19	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HDHGJDOP_01641	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HDHGJDOP_01642	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HDHGJDOP_01643	9.16e-301	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HDHGJDOP_01644	3.99e-192	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HDHGJDOP_01645	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HDHGJDOP_01646	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDHGJDOP_01647	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDHGJDOP_01648	7.4e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HDHGJDOP_01649	3.14e-180	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HDHGJDOP_01650	1.49e-126	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDHGJDOP_01651	1.04e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HDHGJDOP_01652	9.3e-84	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HDHGJDOP_01653	1.04e-249	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDHGJDOP_01654	5.84e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDHGJDOP_01655	6.09e-294	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDHGJDOP_01656	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDHGJDOP_01657	6.84e-60	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HDHGJDOP_01658	3.33e-173	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HDHGJDOP_01659	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HDHGJDOP_01660	5.44e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HDHGJDOP_01661	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HDHGJDOP_01662	7.89e-32	ykzI	-	-	-	-	-	-	-
HDHGJDOP_01663	1.57e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HDHGJDOP_01664	1.08e-92	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HDHGJDOP_01665	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HDHGJDOP_01666	9.3e-32	ylaA	-	-	-	-	-	-	-
HDHGJDOP_01668	1.97e-52	ylaE	-	-	-	-	-	-	-
HDHGJDOP_01669	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HDHGJDOP_01670	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDHGJDOP_01671	1.41e-64	-	-	-	S	-	-	-	YlaH-like protein
HDHGJDOP_01672	7.95e-45	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01673	2.67e-129	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_01674	4.29e-310	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HDHGJDOP_01675	4.45e-104	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HDHGJDOP_01676	7.07e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HDHGJDOP_01677	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HDHGJDOP_01678	3.73e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDHGJDOP_01679	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDHGJDOP_01680	3.88e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HDHGJDOP_01681	2.95e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDHGJDOP_01682	1.61e-250	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HDHGJDOP_01683	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDHGJDOP_01684	3.43e-141	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HDHGJDOP_01685	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HDHGJDOP_01686	1.35e-207	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HDHGJDOP_01687	8.01e-77	ylbA	-	-	S	-	-	-	YugN-like family
HDHGJDOP_01688	1.31e-93	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HDHGJDOP_01689	5.8e-248	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HDHGJDOP_01690	5.5e-83	ylbD	-	-	S	-	-	-	Putative coat protein
HDHGJDOP_01691	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HDHGJDOP_01692	3.73e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HDHGJDOP_01693	4.62e-56	ylbG	-	-	S	-	-	-	UPF0298 protein
HDHGJDOP_01694	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HDHGJDOP_01695	2.38e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDHGJDOP_01696	5.5e-266	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HDHGJDOP_01697	2.03e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HDHGJDOP_01698	7.74e-234	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HDHGJDOP_01699	1.26e-281	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HDHGJDOP_01700	4.69e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HDHGJDOP_01701	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HDHGJDOP_01702	1.65e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HDHGJDOP_01703	2.68e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HDHGJDOP_01704	2.11e-188	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDHGJDOP_01705	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HDHGJDOP_01706	9.07e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDHGJDOP_01707	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDHGJDOP_01708	2.81e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
HDHGJDOP_01709	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDHGJDOP_01710	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HDHGJDOP_01711	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDHGJDOP_01712	2.36e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDHGJDOP_01713	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDHGJDOP_01714	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDHGJDOP_01715	9.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDHGJDOP_01716	3.07e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HDHGJDOP_01717	3.74e-170	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDHGJDOP_01718	3.7e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDHGJDOP_01719	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDHGJDOP_01720	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HDHGJDOP_01721	2.17e-213	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HDHGJDOP_01722	3.64e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_01723	3.8e-178	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_01724	2.58e-183	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HDHGJDOP_01725	1.67e-308	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HDHGJDOP_01726	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HDHGJDOP_01727	3.85e-196	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HDHGJDOP_01728	6.55e-155	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDHGJDOP_01729	8.91e-83	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDHGJDOP_01730	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HDHGJDOP_01731	3.8e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HDHGJDOP_01732	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HDHGJDOP_01733	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDHGJDOP_01734	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HDHGJDOP_01735	8.42e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDHGJDOP_01736	7.29e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDHGJDOP_01737	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDHGJDOP_01738	8.98e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HDHGJDOP_01739	4.15e-204	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDHGJDOP_01740	1.67e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDHGJDOP_01741	4.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDHGJDOP_01742	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HDHGJDOP_01743	2.68e-176	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HDHGJDOP_01744	1.17e-218	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDHGJDOP_01745	2.37e-159	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDHGJDOP_01746	3.5e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDHGJDOP_01748	7.81e-178	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HDHGJDOP_01749	5.26e-223	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HDHGJDOP_01750	5.92e-282	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HDHGJDOP_01751	1.31e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HDHGJDOP_01752	7.4e-179	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HDHGJDOP_01753	1.13e-175	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HDHGJDOP_01754	1.85e-98	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HDHGJDOP_01755	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDHGJDOP_01756	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HDHGJDOP_01757	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HDHGJDOP_01758	8e-194	yloC	-	-	S	-	-	-	stress-induced protein
HDHGJDOP_01759	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HDHGJDOP_01760	1.16e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDHGJDOP_01761	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDHGJDOP_01762	2e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDHGJDOP_01763	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDHGJDOP_01764	1.61e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDHGJDOP_01765	6.66e-215	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDHGJDOP_01766	6.91e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDHGJDOP_01767	7.22e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDHGJDOP_01768	4.92e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HDHGJDOP_01769	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDHGJDOP_01770	6.97e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDHGJDOP_01771	4.85e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDHGJDOP_01772	5.45e-146	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDHGJDOP_01773	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDHGJDOP_01774	6.07e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_01775	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HDHGJDOP_01776	1.69e-152	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HDHGJDOP_01777	3.97e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HDHGJDOP_01778	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDHGJDOP_01779	2.96e-119	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HDHGJDOP_01780	2.58e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDHGJDOP_01781	2.08e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HDHGJDOP_01782	5.81e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDHGJDOP_01783	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDHGJDOP_01784	2.48e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDHGJDOP_01785	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDHGJDOP_01786	2.09e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDHGJDOP_01787	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDHGJDOP_01788	2e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDHGJDOP_01789	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HDHGJDOP_01790	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HDHGJDOP_01791	5.66e-79	ylqD	-	-	S	-	-	-	YlqD protein
HDHGJDOP_01792	4.17e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDHGJDOP_01793	2.22e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDHGJDOP_01794	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDHGJDOP_01795	5.95e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDHGJDOP_01796	1.87e-171	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDHGJDOP_01797	0.0	ylqG	-	-	-	-	-	-	-
HDHGJDOP_01798	6.68e-57	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HDHGJDOP_01799	1.66e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HDHGJDOP_01800	2.17e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HDHGJDOP_01801	6.19e-208	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HDHGJDOP_01802	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDHGJDOP_01803	1.05e-311	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDHGJDOP_01804	1.42e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HDHGJDOP_01805	1.43e-118	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDHGJDOP_01806	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDHGJDOP_01807	7.94e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HDHGJDOP_01808	3.14e-81	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HDHGJDOP_01809	1.46e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HDHGJDOP_01810	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HDHGJDOP_01811	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HDHGJDOP_01812	3.52e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDHGJDOP_01813	6.92e-116	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HDHGJDOP_01814	2.02e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HDHGJDOP_01815	8.85e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HDHGJDOP_01816	3.78e-76	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HDHGJDOP_01817	7.87e-242	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HDHGJDOP_01818	2.43e-90	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HDHGJDOP_01819	2.56e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HDHGJDOP_01820	3.66e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HDHGJDOP_01821	1.28e-228	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDHGJDOP_01822	9.42e-231	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HDHGJDOP_01823	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HDHGJDOP_01824	6.3e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HDHGJDOP_01825	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HDHGJDOP_01826	9.02e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HDHGJDOP_01827	4.51e-165	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HDHGJDOP_01828	3.29e-238	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDHGJDOP_01829	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDHGJDOP_01830	4.59e-210	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HDHGJDOP_01831	1.43e-196	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HDHGJDOP_01832	5.21e-222	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HDHGJDOP_01833	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HDHGJDOP_01834	1.01e-104	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HDHGJDOP_01835	1.39e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HDHGJDOP_01836	6.74e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HDHGJDOP_01837	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_01838	2.54e-84	ylxL	-	-	-	-	-	-	-
HDHGJDOP_01839	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDHGJDOP_01840	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDHGJDOP_01841	2.03e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDHGJDOP_01842	1.59e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDHGJDOP_01843	2.49e-183	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDHGJDOP_01844	1.48e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HDHGJDOP_01845	8.59e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HDHGJDOP_01846	2.58e-293	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HDHGJDOP_01847	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDHGJDOP_01848	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDHGJDOP_01849	9.4e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDHGJDOP_01850	1.35e-262	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDHGJDOP_01851	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HDHGJDOP_01852	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HDHGJDOP_01853	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDHGJDOP_01854	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HDHGJDOP_01855	2.38e-67	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDHGJDOP_01856	2.64e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDHGJDOP_01857	6.31e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDHGJDOP_01858	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDHGJDOP_01859	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDHGJDOP_01860	2.3e-229	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HDHGJDOP_01861	9.79e-298	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HDHGJDOP_01862	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HDHGJDOP_01863	4.32e-202	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HDHGJDOP_01864	6.97e-131	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HDHGJDOP_01865	5.33e-244	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDHGJDOP_01866	3.69e-278	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDHGJDOP_01867	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDHGJDOP_01868	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDHGJDOP_01869	5.34e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HDHGJDOP_01870	7.4e-41	-	-	-	S	-	-	-	YlzJ-like protein
HDHGJDOP_01871	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDHGJDOP_01872	1.38e-166	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_01873	2.76e-290	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_01874	7.8e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_01875	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HDHGJDOP_01876	8.12e-300	albE	-	-	S	-	-	-	Peptidase M16
HDHGJDOP_01877	2.09e-303	ymfH	-	-	S	-	-	-	zinc protease
HDHGJDOP_01878	1.13e-161	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HDHGJDOP_01879	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HDHGJDOP_01880	3.66e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HDHGJDOP_01881	2.26e-166	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HDHGJDOP_01882	2.75e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDHGJDOP_01883	2.57e-291	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HDHGJDOP_01884	8.4e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDHGJDOP_01885	4.31e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
HDHGJDOP_01886	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDHGJDOP_01887	3.06e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HDHGJDOP_01888	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HDHGJDOP_01889	1.32e-247	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HDHGJDOP_01890	2.28e-270	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDHGJDOP_01891	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HDHGJDOP_01892	2.37e-85	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HDHGJDOP_01893	3.93e-116	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HDHGJDOP_01894	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDHGJDOP_01895	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDHGJDOP_01896	3.58e-160	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HDHGJDOP_01897	1.77e-202	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HDHGJDOP_01898	9.59e-220	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HDHGJDOP_01899	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HDHGJDOP_01900	6.16e-48	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HDHGJDOP_01901	9.98e-307	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HDHGJDOP_01902	7.4e-179	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HDHGJDOP_01903	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HDHGJDOP_01904	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HDHGJDOP_01905	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HDHGJDOP_01906	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HDHGJDOP_01907	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HDHGJDOP_01908	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HDHGJDOP_01909	4.53e-283	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HDHGJDOP_01910	3e-93	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HDHGJDOP_01911	3.52e-149	yoaK	-	-	S	-	-	-	Membrane
HDHGJDOP_01912	9.32e-81	ymzB	-	-	-	-	-	-	-
HDHGJDOP_01913	9.4e-317	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HDHGJDOP_01915	3.08e-151	ymaC	-	-	S	-	-	-	Replication protein
HDHGJDOP_01916	9.17e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HDHGJDOP_01917	1.76e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HDHGJDOP_01918	1.17e-62	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HDHGJDOP_01920	9.08e-72	ymaF	-	-	S	-	-	-	YmaF family
HDHGJDOP_01921	7.19e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDHGJDOP_01922	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HDHGJDOP_01923	1.87e-53	-	-	-	-	-	-	-	-
HDHGJDOP_01924	2.31e-29	ymzA	-	-	-	-	-	-	-
HDHGJDOP_01925	4.43e-77	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HDHGJDOP_01926	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHGJDOP_01927	5.94e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHGJDOP_01928	2.21e-132	ymaB	-	-	S	-	-	-	MutT family
HDHGJDOP_01929	1.35e-135	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_01930	2.58e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HDHGJDOP_01931	9.64e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDHGJDOP_01932	5.35e-307	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HDHGJDOP_01933	8.18e-86	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HDHGJDOP_01934	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDHGJDOP_01935	1.1e-192	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDHGJDOP_01937	1.36e-111	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HDHGJDOP_01938	7.74e-121	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HDHGJDOP_01939	1.82e-187	-	-	-	V	-	-	-	HNH endonuclease
HDHGJDOP_01940	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HDHGJDOP_01941	3.18e-67	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HDHGJDOP_01943	2.08e-162	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HDHGJDOP_01944	2.1e-52	-	-	-	S	-	-	-	YolD-like protein
HDHGJDOP_01945	8.79e-283	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDHGJDOP_01946	5.27e-79	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HDHGJDOP_01947	1.08e-59	cmoA	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
HDHGJDOP_01948	9.95e-38	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_01949	2.54e-265	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HDHGJDOP_01950	4.44e-150	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HDHGJDOP_01951	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HDHGJDOP_01952	2.25e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HDHGJDOP_01953	3.77e-225	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HDHGJDOP_01955	7.33e-250	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HDHGJDOP_01956	0.000425	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HDHGJDOP_01957	0.0	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HDHGJDOP_01958	2.84e-123	tnpR	-	-	L	-	-	-	resolvase
HDHGJDOP_01959	4.04e-103	-	-	-	-	-	-	-	-
HDHGJDOP_01961	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_01962	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_01963	4.11e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HDHGJDOP_01964	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HDHGJDOP_01965	6.17e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HDHGJDOP_01966	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_01967	6.56e-192	-	-	-	S	-	-	-	membrane
HDHGJDOP_01968	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_01969	0.0	-	-	-	I	-	-	-	PLD-like domain
HDHGJDOP_01970	1.16e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_01972	1.08e-86	dinB	-	-	S	-	-	-	DinB family
HDHGJDOP_01973	1.82e-231	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDHGJDOP_01974	5.82e-16	-	-	-	-	-	-	-	-
HDHGJDOP_01975	2.04e-10	-	-	-	-	-	-	-	-
HDHGJDOP_01976	1.95e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HDHGJDOP_01977	1.69e-13	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HDHGJDOP_01978	1.52e-164	yoaP	-	-	K	-	-	-	YoaP-like
HDHGJDOP_01979	1.09e-117	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_01981	1.87e-53	-	-	-	-	-	-	-	-
HDHGJDOP_01983	2.39e-130	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HDHGJDOP_01984	1.1e-237	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_01985	3.2e-150	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HDHGJDOP_01986	9.32e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HDHGJDOP_01987	1.97e-119	yvgO	-	-	-	-	-	-	-
HDHGJDOP_01989	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HDHGJDOP_01990	1.33e-43	-	-	-	S	-	-	-	TM2 domain
HDHGJDOP_01991	9.69e-99	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HDHGJDOP_01992	3.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HDHGJDOP_01993	2.53e-162	yndL	-	-	S	-	-	-	Replication protein
HDHGJDOP_01994	4.12e-10	-	-	-	-	-	-	-	-
HDHGJDOP_01995	4.95e-182	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HDHGJDOP_01996	2.23e-86	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HDHGJDOP_01998	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDHGJDOP_01999	4.8e-66	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HDHGJDOP_02000	4.8e-141	yneB	-	-	L	-	-	-	resolvase
HDHGJDOP_02001	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HDHGJDOP_02002	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDHGJDOP_02003	3.48e-103	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HDHGJDOP_02004	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HDHGJDOP_02005	8.06e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HDHGJDOP_02006	1.38e-158	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HDHGJDOP_02007	4.11e-75	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HDHGJDOP_02008	7.59e-97	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HDHGJDOP_02009	4.28e-92	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HDHGJDOP_02010	2.64e-77	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HDHGJDOP_02011	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HDHGJDOP_02012	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HDHGJDOP_02013	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDHGJDOP_02014	4.36e-114	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDHGJDOP_02016	4.08e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HDHGJDOP_02017	8.11e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HDHGJDOP_02018	5.95e-65	yneQ	-	-	-	-	-	-	-
HDHGJDOP_02019	9.38e-58	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HDHGJDOP_02020	1.51e-119	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDHGJDOP_02021	1.41e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HDHGJDOP_02022	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDHGJDOP_02023	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDHGJDOP_02024	2.21e-19	-	-	-	-	-	-	-	-
HDHGJDOP_02025	2.04e-60	ynfC	-	-	-	-	-	-	-
HDHGJDOP_02026	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HDHGJDOP_02027	1.56e-28	yndG	-	-	S	-	-	-	DoxX-like family
HDHGJDOP_02028	2.24e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HDHGJDOP_02029	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HDHGJDOP_02030	2.03e-67	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HDHGJDOP_02031	3.49e-282	-	-	-	T	-	-	-	Histidine kinase
HDHGJDOP_02032	7.49e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HDHGJDOP_02033	4.05e-303	-	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HDHGJDOP_02034	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HDHGJDOP_02035	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_02036	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_02037	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_02038	3.84e-262	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HDHGJDOP_02039	3.62e-156	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HDHGJDOP_02040	5.28e-135	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDHGJDOP_02041	2.32e-145	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDHGJDOP_02042	6.2e-207	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HDHGJDOP_02043	4.21e-242	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HDHGJDOP_02044	7.37e-158	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HDHGJDOP_02045	3.12e-254	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDHGJDOP_02046	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HDHGJDOP_02047	8.22e-171	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HDHGJDOP_02048	1.02e-88	yngA	-	-	S	-	-	-	membrane
HDHGJDOP_02049	1.01e-196	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDHGJDOP_02050	6.22e-134	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_02051	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDHGJDOP_02052	2.54e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HDHGJDOP_02053	2.16e-208	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HDHGJDOP_02054	2.28e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HDHGJDOP_02055	1.6e-304	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HDHGJDOP_02056	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDHGJDOP_02057	5.24e-43	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDHGJDOP_02058	6.97e-264	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HDHGJDOP_02059	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HDHGJDOP_02060	9.31e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HDHGJDOP_02061	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HDHGJDOP_02062	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_02063	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HDHGJDOP_02064	1.56e-229	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDHGJDOP_02065	1.31e-305	yoeA	-	-	V	-	-	-	MATE efflux family protein
HDHGJDOP_02066	8.33e-122	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HDHGJDOP_02068	7.69e-123	-	-	-	L	-	-	-	Integrase
HDHGJDOP_02069	7.83e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HDHGJDOP_02070	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HDHGJDOP_02071	5.29e-237	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HDHGJDOP_02072	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HDHGJDOP_02073	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDHGJDOP_02074	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HDHGJDOP_02075	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HDHGJDOP_02076	7.74e-201	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02077	3.37e-251	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDHGJDOP_02078	5.78e-173	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDHGJDOP_02079	6.69e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HDHGJDOP_02080	4.03e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_02081	1.23e-49	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDHGJDOP_02082	1.2e-147	yoxB	-	-	-	-	-	-	-
HDHGJDOP_02083	1.16e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_02084	0.0	-	-	-	I	-	-	-	PLD-like domain
HDHGJDOP_02085	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_02086	6.56e-192	-	-	-	S	-	-	-	membrane
HDHGJDOP_02087	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_02088	6.17e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HDHGJDOP_02089	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HDHGJDOP_02090	4.11e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HDHGJDOP_02091	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_02092	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_02094	4.04e-103	-	-	-	-	-	-	-	-
HDHGJDOP_02095	2.84e-123	tnpR	-	-	L	-	-	-	resolvase
HDHGJDOP_02096	0.0	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HDHGJDOP_02097	5.69e-249	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HDHGJDOP_02098	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HDHGJDOP_02099	4.77e-203	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDHGJDOP_02100	1.6e-13	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDHGJDOP_02101	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDHGJDOP_02102	6.3e-36	yoaF	-	-	-	-	-	-	-
HDHGJDOP_02104	6.83e-121	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_02105	1.52e-38	-	-	-	-	-	-	-	-
HDHGJDOP_02108	2.04e-68	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HDHGJDOP_02109	6.26e-156	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDHGJDOP_02110	1.44e-110	yobS	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02111	1.22e-159	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HDHGJDOP_02112	1.29e-117	yobW	-	-	-	-	-	-	-
HDHGJDOP_02113	3.14e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HDHGJDOP_02114	5.45e-154	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDHGJDOP_02115	5.42e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HDHGJDOP_02116	9.94e-172	-	-	-	J	-	-	-	Protein required for attachment to host cells
HDHGJDOP_02117	2.99e-119	yocC	-	-	-	-	-	-	-
HDHGJDOP_02118	8.07e-233	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HDHGJDOP_02120	6.61e-157	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HDHGJDOP_02121	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDHGJDOP_02123	2.71e-143	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDHGJDOP_02124	7.44e-78	yocK	-	-	T	-	-	-	general stress protein
HDHGJDOP_02126	1.16e-11	yocN	-	-	-	-	-	-	-
HDHGJDOP_02127	2.21e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDHGJDOP_02128	8.77e-41	yozN	-	-	-	-	-	-	-
HDHGJDOP_02129	1.83e-49	yocN	-	-	-	-	-	-	-
HDHGJDOP_02130	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HDHGJDOP_02132	4.69e-43	yozC	-	-	-	-	-	-	-
HDHGJDOP_02133	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDHGJDOP_02134	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HDHGJDOP_02135	5.12e-207	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HDHGJDOP_02136	2.2e-293	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDHGJDOP_02137	3.02e-209	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HDHGJDOP_02138	8.69e-156	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HDHGJDOP_02139	1.12e-257	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HDHGJDOP_02140	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HDHGJDOP_02141	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HDHGJDOP_02142	2e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HDHGJDOP_02143	1.31e-135	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HDHGJDOP_02144	1.68e-276	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HDHGJDOP_02145	6.89e-278	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HDHGJDOP_02146	3.97e-136	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDHGJDOP_02148	1.51e-297	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HDHGJDOP_02149	6.24e-187	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDHGJDOP_02150	2.61e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HDHGJDOP_02151	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HDHGJDOP_02152	3.66e-31	-	-	-	-	-	-	-	-
HDHGJDOP_02153	3.04e-203	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HDHGJDOP_02154	1.83e-101	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HDHGJDOP_02156	9.37e-83	iolK	-	-	S	-	-	-	tautomerase
HDHGJDOP_02157	1.93e-69	yodB	-	-	K	-	-	-	transcriptional
HDHGJDOP_02158	6.14e-135	yodC	-	-	C	-	-	-	nitroreductase
HDHGJDOP_02159	1.12e-118	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HDHGJDOP_02160	8.81e-212	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HDHGJDOP_02161	1.14e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HDHGJDOP_02162	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDHGJDOP_02163	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HDHGJDOP_02164	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDHGJDOP_02165	3.79e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02166	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDHGJDOP_02167	1.3e-123	yodH	-	-	Q	-	-	-	Methyltransferase
HDHGJDOP_02168	2.3e-30	yodI	-	-	-	-	-	-	-
HDHGJDOP_02169	8.69e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HDHGJDOP_02170	4.29e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HDHGJDOP_02172	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
HDHGJDOP_02173	8.36e-131	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDHGJDOP_02174	1.97e-33	yozD	-	-	S	-	-	-	YozD-like protein
HDHGJDOP_02176	1.18e-155	yodN	-	-	-	-	-	-	-
HDHGJDOP_02177	1.39e-66	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_02178	2.87e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HDHGJDOP_02179	6.45e-59	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HDHGJDOP_02180	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HDHGJDOP_02181	4.82e-180	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HDHGJDOP_02182	4.03e-315	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HDHGJDOP_02183	8.26e-154	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDHGJDOP_02184	5.2e-156	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDHGJDOP_02185	2.06e-297	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDHGJDOP_02187	3.54e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HDHGJDOP_02189	3.96e-176	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HDHGJDOP_02190	1.17e-286	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HDHGJDOP_02191	2.84e-54	cgeC	-	-	-	ko:K06321	-	ko00000	-
HDHGJDOP_02192	1.08e-81	cgeA	-	-	-	ko:K06319	-	ko00000	-
HDHGJDOP_02193	6.45e-215	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HDHGJDOP_02194	7.88e-267	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HDHGJDOP_02195	5.78e-91	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HDHGJDOP_02198	5.97e-151	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
HDHGJDOP_02200	6.05e-22	-	-	-	S	-	-	-	Regulatory protein YrvL
HDHGJDOP_02201	6.94e-262	yokA	-	-	L	-	-	-	Recombinase
HDHGJDOP_02202	1.29e-129	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HDHGJDOP_02203	2.47e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HDHGJDOP_02204	1.34e-130	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDHGJDOP_02205	3.91e-88	ypoP	-	-	K	-	-	-	transcriptional
HDHGJDOP_02206	2.45e-122	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_02207	3.62e-167	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDHGJDOP_02208	2.24e-131	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HDHGJDOP_02209	3.66e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HDHGJDOP_02210	7.88e-305	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDHGJDOP_02211	1.54e-207	yplP	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02212	7.14e-141	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HDHGJDOP_02213	9.83e-141	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDHGJDOP_02214	6.3e-110	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDHGJDOP_02215	2.08e-202	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDHGJDOP_02216	1.41e-142	ypjP	-	-	S	-	-	-	YpjP-like protein
HDHGJDOP_02217	2.63e-167	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HDHGJDOP_02218	1.38e-98	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HDHGJDOP_02219	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HDHGJDOP_02220	8.12e-197	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HDHGJDOP_02221	1.69e-116	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HDHGJDOP_02222	4.95e-107	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HDHGJDOP_02224	1.56e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDHGJDOP_02225	1.01e-272	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HDHGJDOP_02226	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HDHGJDOP_02227	4.27e-16	degR	-	-	-	-	-	-	-
HDHGJDOP_02228	5.37e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HDHGJDOP_02229	6.37e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
HDHGJDOP_02230	4.29e-152	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HDHGJDOP_02231	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HDHGJDOP_02232	3.51e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HDHGJDOP_02234	2.07e-204	ypcP	-	-	L	-	-	-	5'3' exonuclease
HDHGJDOP_02235	5.97e-11	-	-	-	-	-	-	-	-
HDHGJDOP_02236	3e-45	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HDHGJDOP_02237	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HDHGJDOP_02238	2.25e-111	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HDHGJDOP_02239	3.81e-254	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HDHGJDOP_02240	2.22e-130	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_02241	8.02e-60	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HDHGJDOP_02242	2.2e-09	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HDHGJDOP_02243	4.64e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HDHGJDOP_02244	8.76e-124	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDHGJDOP_02245	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HDHGJDOP_02246	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HDHGJDOP_02248	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HDHGJDOP_02249	2.19e-96	yqgA	-	-	-	-	-	-	-
HDHGJDOP_02250	3.07e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDHGJDOP_02251	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDHGJDOP_02252	3.67e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HDHGJDOP_02253	5.48e-36	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HDHGJDOP_02255	3.33e-285	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HDHGJDOP_02256	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HDHGJDOP_02257	6.99e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HDHGJDOP_02258	5.45e-79	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDHGJDOP_02259	2.64e-59	yppG	-	-	S	-	-	-	YppG-like protein
HDHGJDOP_02264	1.05e-225	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HDHGJDOP_02265	8.49e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDHGJDOP_02266	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDHGJDOP_02267	4.6e-113	ypoC	-	-	-	-	-	-	-
HDHGJDOP_02268	1.63e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDHGJDOP_02269	8.05e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HDHGJDOP_02270	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HDHGJDOP_02271	1.1e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDHGJDOP_02272	2.74e-95	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_02273	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HDHGJDOP_02274	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HDHGJDOP_02275	1.98e-83	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HDHGJDOP_02276	4.82e-194	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HDHGJDOP_02277	1.89e-191	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HDHGJDOP_02278	2.04e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDHGJDOP_02279	1.53e-266	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDHGJDOP_02280	7.01e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HDHGJDOP_02281	3.8e-162	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HDHGJDOP_02282	3.58e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HDHGJDOP_02283	9.38e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDHGJDOP_02284	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HDHGJDOP_02285	6.13e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_02286	5.93e-282	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HDHGJDOP_02287	1.09e-177	ypjB	-	-	S	-	-	-	sporulation protein
HDHGJDOP_02288	1.23e-125	ypjA	-	-	S	-	-	-	membrane
HDHGJDOP_02289	9.48e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HDHGJDOP_02290	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HDHGJDOP_02291	2.27e-124	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HDHGJDOP_02292	1.21e-94	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HDHGJDOP_02293	2.14e-128	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HDHGJDOP_02294	7.68e-292	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HDHGJDOP_02295	1.08e-289	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDHGJDOP_02296	9.38e-256	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDHGJDOP_02297	2.67e-251	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDHGJDOP_02298	1.08e-175	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDHGJDOP_02299	9.2e-286	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDHGJDOP_02300	2.57e-141	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HDHGJDOP_02301	1.15e-158	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HDHGJDOP_02302	3.8e-201	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDHGJDOP_02303	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDHGJDOP_02304	8.09e-77	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HDHGJDOP_02305	1.14e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDHGJDOP_02306	3.26e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDHGJDOP_02307	9.33e-177	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HDHGJDOP_02308	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HDHGJDOP_02309	5.39e-250	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDHGJDOP_02310	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDHGJDOP_02311	2.68e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HDHGJDOP_02312	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HDHGJDOP_02313	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HDHGJDOP_02314	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDHGJDOP_02315	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HDHGJDOP_02317	2.47e-166	yphF	-	-	-	-	-	-	-
HDHGJDOP_02318	1.13e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HDHGJDOP_02319	9.14e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDHGJDOP_02320	2.86e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDHGJDOP_02321	6.38e-129	yphA	-	-	-	-	-	-	-
HDHGJDOP_02322	1.32e-12	-	-	-	S	-	-	-	YpzI-like protein
HDHGJDOP_02323	4.76e-228	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDHGJDOP_02324	3.17e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HDHGJDOP_02325	3.75e-142	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDHGJDOP_02326	1.12e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HDHGJDOP_02327	6.58e-72	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HDHGJDOP_02328	1.1e-311	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HDHGJDOP_02329	2.15e-203	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HDHGJDOP_02330	1.51e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HDHGJDOP_02331	5.93e-236	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HDHGJDOP_02332	8.6e-310	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDHGJDOP_02333	7.9e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDHGJDOP_02334	5.62e-181	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HDHGJDOP_02335	3.73e-109	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HDHGJDOP_02336	8.85e-110	ypbE	-	-	M	-	-	-	Lysin motif
HDHGJDOP_02337	1.84e-123	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HDHGJDOP_02338	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDHGJDOP_02339	2.97e-244	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HDHGJDOP_02340	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HDHGJDOP_02341	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDHGJDOP_02342	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDHGJDOP_02343	6.63e-216	rsiX	-	-	-	-	-	-	-
HDHGJDOP_02344	3.09e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HDHGJDOP_02345	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_02346	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_02347	3.09e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HDHGJDOP_02348	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HDHGJDOP_02349	9.77e-125	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HDHGJDOP_02350	1.74e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDHGJDOP_02351	7.39e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HDHGJDOP_02352	6.22e-134	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HDHGJDOP_02353	2.36e-268	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDHGJDOP_02354	5.9e-107	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HDHGJDOP_02355	1.3e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDHGJDOP_02356	4.93e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDHGJDOP_02358	2.41e-113	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HDHGJDOP_02359	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDHGJDOP_02360	1.4e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDHGJDOP_02361	8.2e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HDHGJDOP_02362	3.81e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HDHGJDOP_02363	1.24e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDHGJDOP_02364	7.86e-68	ypuD	-	-	-	-	-	-	-
HDHGJDOP_02365	8.88e-122	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDHGJDOP_02366	6.23e-102	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HDHGJDOP_02367	1.18e-103	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDHGJDOP_02368	3.35e-194	ypuA	-	-	S	-	-	-	Secreted protein
HDHGJDOP_02369	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDHGJDOP_02370	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HDHGJDOP_02371	1.2e-138	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HDHGJDOP_02372	3.57e-74	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HDHGJDOP_02373	9.17e-241	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HDHGJDOP_02374	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HDHGJDOP_02375	9.1e-141	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HDHGJDOP_02376	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_02377	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HDHGJDOP_02378	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HDHGJDOP_02379	5.58e-270	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDHGJDOP_02380	8.69e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HDHGJDOP_02381	4.39e-288	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDHGJDOP_02382	1.78e-210	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HDHGJDOP_02383	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HDHGJDOP_02384	3.08e-102	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDHGJDOP_02385	4.12e-141	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HDHGJDOP_02386	2.87e-43	yqkK	-	-	-	-	-	-	-
HDHGJDOP_02387	5.05e-33	-	-	-	-	-	-	-	-
HDHGJDOP_02388	9.28e-307	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HDHGJDOP_02389	3.56e-313	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HDHGJDOP_02390	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HDHGJDOP_02391	4.88e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HDHGJDOP_02392	2.32e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02393	1.43e-271	yqxK	-	-	L	-	-	-	DNA helicase
HDHGJDOP_02394	1.42e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HDHGJDOP_02395	5.78e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HDHGJDOP_02396	2.34e-211	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HDHGJDOP_02397	3.06e-15	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HDHGJDOP_02398	2.33e-170	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDHGJDOP_02399	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HDHGJDOP_02400	1.22e-76	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HDHGJDOP_02401	1.93e-212	yqkA	-	-	K	-	-	-	GrpB protein
HDHGJDOP_02402	1.92e-08	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HDHGJDOP_02403	2.7e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HDHGJDOP_02404	1.01e-293	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDHGJDOP_02405	7.27e-73	-	-	-	S	-	-	-	YolD-like protein
HDHGJDOP_02407	7.76e-204	yueF	-	-	S	-	-	-	transporter activity
HDHGJDOP_02409	3.01e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HDHGJDOP_02410	4.1e-307	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HDHGJDOP_02411	2.99e-174	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_02412	1.11e-213	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HDHGJDOP_02413	7.56e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDHGJDOP_02414	9.08e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HDHGJDOP_02415	2.42e-61	-	-	-	S	-	-	-	GlpM protein
HDHGJDOP_02416	1.64e-120	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HDHGJDOP_02417	4.49e-63	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HDHGJDOP_02418	2.4e-184	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDHGJDOP_02419	4.44e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDHGJDOP_02420	2.97e-215	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDHGJDOP_02421	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDHGJDOP_02422	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDHGJDOP_02423	7.78e-294	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDHGJDOP_02424	1.36e-36	yqzJ	-	-	-	-	-	-	-
HDHGJDOP_02425	6.56e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDHGJDOP_02426	4.14e-256	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HDHGJDOP_02427	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDHGJDOP_02428	6.09e-92	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HDHGJDOP_02430	3.99e-118	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_02431	1.79e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HDHGJDOP_02432	1.13e-160	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HDHGJDOP_02433	7.04e-140	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HDHGJDOP_02434	2.18e-170	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDHGJDOP_02435	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HDHGJDOP_02436	3.22e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDHGJDOP_02437	2.69e-265	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDHGJDOP_02438	4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDHGJDOP_02439	4.18e-217	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDHGJDOP_02440	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDHGJDOP_02441	3.86e-260	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HDHGJDOP_02442	5.27e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDHGJDOP_02443	1.53e-191	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HDHGJDOP_02444	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HDHGJDOP_02445	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HDHGJDOP_02446	7.1e-199	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HDHGJDOP_02447	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HDHGJDOP_02448	9.85e-261	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HDHGJDOP_02449	9.37e-256	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HDHGJDOP_02450	8.59e-59	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HDHGJDOP_02451	1.22e-101	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HDHGJDOP_02452	1.21e-266	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HDHGJDOP_02453	1.04e-163	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HDHGJDOP_02454	1.94e-127	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HDHGJDOP_02456	2.52e-119	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HDHGJDOP_02457	3.85e-144	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HDHGJDOP_02459	2.85e-266	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HDHGJDOP_02462	4.31e-260	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDHGJDOP_02463	4.13e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HDHGJDOP_02464	9.07e-297	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HDHGJDOP_02465	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDHGJDOP_02466	1.03e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDHGJDOP_02467	2.69e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HDHGJDOP_02468	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDHGJDOP_02469	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDHGJDOP_02470	4.44e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDHGJDOP_02471	5.36e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDHGJDOP_02472	2.51e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDHGJDOP_02473	2.58e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDHGJDOP_02474	5.53e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_02475	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HDHGJDOP_02476	2.59e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDHGJDOP_02477	1.88e-86	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HDHGJDOP_02478	1.3e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HDHGJDOP_02479	1.74e-129	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HDHGJDOP_02480	3.02e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HDHGJDOP_02481	5.28e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HDHGJDOP_02482	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HDHGJDOP_02483	2.23e-108	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HDHGJDOP_02484	7.55e-213	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HDHGJDOP_02485	1.64e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HDHGJDOP_02486	9.69e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDHGJDOP_02487	2.75e-245	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HDHGJDOP_02488	2.13e-113	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HDHGJDOP_02489	1.12e-215	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HDHGJDOP_02490	8.59e-80	yqhP	-	-	-	-	-	-	-
HDHGJDOP_02491	2.51e-203	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HDHGJDOP_02492	1.14e-96	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HDHGJDOP_02493	1.25e-201	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HDHGJDOP_02494	2.33e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HDHGJDOP_02495	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDHGJDOP_02496	2.14e-313	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDHGJDOP_02497	7.69e-254	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HDHGJDOP_02498	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDHGJDOP_02499	8.42e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HDHGJDOP_02500	1.3e-29	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HDHGJDOP_02501	2.27e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HDHGJDOP_02502	8.28e-178	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HDHGJDOP_02503	5.48e-95	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HDHGJDOP_02504	7.32e-144	yqxM	-	-	-	ko:K19433	-	ko00000	-
HDHGJDOP_02505	3.98e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HDHGJDOP_02506	9.56e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
HDHGJDOP_02507	8.44e-75	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HDHGJDOP_02508	2.45e-28	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HDHGJDOP_02509	1.56e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HDHGJDOP_02510	3.1e-91	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HDHGJDOP_02511	1.5e-64	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HDHGJDOP_02512	5.79e-227	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HDHGJDOP_02513	5.85e-253	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDHGJDOP_02514	1.34e-231	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HDHGJDOP_02515	2.13e-294	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HDHGJDOP_02516	2.41e-175	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDHGJDOP_02518	2.15e-82	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HDHGJDOP_02519	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HDHGJDOP_02520	2e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HDHGJDOP_02521	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HDHGJDOP_02522	2.02e-63	dglA	-	-	S	-	-	-	Thiamine-binding protein
HDHGJDOP_02523	1.57e-239	yqgU	-	-	-	-	-	-	-
HDHGJDOP_02524	1.33e-256	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HDHGJDOP_02525	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HDHGJDOP_02526	1.87e-37	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HDHGJDOP_02527	2.58e-269	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HDHGJDOP_02528	5.38e-11	yqgO	-	-	-	-	-	-	-
HDHGJDOP_02529	1.16e-114	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDHGJDOP_02530	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDHGJDOP_02531	3.42e-68	yqzD	-	-	-	-	-	-	-
HDHGJDOP_02532	1.97e-96	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDHGJDOP_02533	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDHGJDOP_02534	2.99e-179	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDHGJDOP_02535	1.88e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HDHGJDOP_02536	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDHGJDOP_02537	6.14e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDHGJDOP_02538	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HDHGJDOP_02539	5.94e-283	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HDHGJDOP_02540	8.52e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HDHGJDOP_02541	7.59e-97	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HDHGJDOP_02542	8.5e-165	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HDHGJDOP_02543	5.95e-59	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HDHGJDOP_02544	1.09e-253	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HDHGJDOP_02545	3.9e-79	yqfX	-	-	S	-	-	-	membrane
HDHGJDOP_02546	3.23e-139	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HDHGJDOP_02547	2.63e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HDHGJDOP_02548	2.47e-195	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_02549	2.9e-47	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HDHGJDOP_02550	9.16e-209	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDHGJDOP_02551	3.91e-304	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDHGJDOP_02552	7.12e-57	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HDHGJDOP_02553	4.12e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HDHGJDOP_02554	2.97e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDHGJDOP_02555	1.65e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDHGJDOP_02556	7.67e-80	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HDHGJDOP_02557	8e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDHGJDOP_02558	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDHGJDOP_02559	4.54e-111	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HDHGJDOP_02560	1.75e-188	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDHGJDOP_02561	3.41e-144	ccpN	-	-	K	-	-	-	CBS domain
HDHGJDOP_02562	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HDHGJDOP_02563	2.03e-220	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HDHGJDOP_02564	1.9e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDHGJDOP_02565	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HDHGJDOP_02566	2.86e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDHGJDOP_02567	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDHGJDOP_02568	8.76e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HDHGJDOP_02569	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDHGJDOP_02570	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HDHGJDOP_02571	4.78e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HDHGJDOP_02572	3.96e-273	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HDHGJDOP_02573	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HDHGJDOP_02574	2.58e-48	yqfB	-	-	-	-	-	-	-
HDHGJDOP_02575	1.22e-186	yqfA	-	-	S	-	-	-	UPF0365 protein
HDHGJDOP_02576	3.91e-288	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HDHGJDOP_02577	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HDHGJDOP_02578	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HDHGJDOP_02579	1.99e-194	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HDHGJDOP_02580	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HDHGJDOP_02581	3.96e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDHGJDOP_02582	1.27e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HDHGJDOP_02583	3.18e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDHGJDOP_02584	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDHGJDOP_02585	1.99e-104	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDHGJDOP_02586	1.11e-239	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDHGJDOP_02587	3.95e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HDHGJDOP_02588	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDHGJDOP_02589	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HDHGJDOP_02590	2.6e-279	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HDHGJDOP_02591	1.02e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HDHGJDOP_02592	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HDHGJDOP_02593	6.09e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HDHGJDOP_02594	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HDHGJDOP_02595	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HDHGJDOP_02596	1.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HDHGJDOP_02597	1.14e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDHGJDOP_02598	1.98e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
HDHGJDOP_02599	9.39e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDHGJDOP_02600	3.25e-131	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HDHGJDOP_02601	1.38e-138	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDHGJDOP_02602	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HDHGJDOP_02603	2.83e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDHGJDOP_02604	1.87e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HDHGJDOP_02605	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HDHGJDOP_02607	3.99e-176	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDHGJDOP_02608	3.16e-178	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HDHGJDOP_02609	3.41e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_02611	9.72e-08	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDHGJDOP_02612	2.47e-274	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HDHGJDOP_02613	6.78e-160	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDHGJDOP_02614	1.82e-17	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HDHGJDOP_02615	1.46e-194	-	-	-	L	-	-	-	AAA ATPase domain
HDHGJDOP_02616	1.18e-50	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDHGJDOP_02619	7.65e-201	smvA	-	-	EGP	ko:K08167	-	ko00000,ko00002,ko01504,ko02000	Major facilitator superfamily
HDHGJDOP_02620	2.93e-98	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	TIGRFAM glutamine amidotransferase of anthranilate synthase
HDHGJDOP_02621	1.71e-224	-	4.1.3.27, 4.2.99.21, 5.4.4.2	-	EH	ko:K01657,ko:K04781	ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I domain protein
HDHGJDOP_02622	1.69e-220	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	phenylacetate-CoA ligase activity
HDHGJDOP_02623	0.0	-	-	-	Q	-	-	-	AMP-binding enzyme C-terminal domain
HDHGJDOP_02624	4.19e-152	-	-	-	S	-	-	-	Winged helix DNA-binding domain
HDHGJDOP_02625	5.94e-257	glyA_1	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDHGJDOP_02626	2.82e-142	mchB	-	-	Q	ko:K12240	ko01053,map01053	ko00000,ko00001,ko01008	Thioesterase involved in non-ribosomal peptide biosynthesis
HDHGJDOP_02628	1.28e-206	-	-	-	K	ko:K13572	-	ko00000,ko03051	HTH domain
HDHGJDOP_02629	2.68e-135	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HDHGJDOP_02630	8.14e-25	-	-	-	-	-	-	-	-
HDHGJDOP_02634	5.49e-13	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HDHGJDOP_02635	8.55e-19	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HDHGJDOP_02636	8.03e-141	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDHGJDOP_02637	1.23e-174	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Reductase
HDHGJDOP_02638	1.29e-89	-	-	-	K	-	-	-	MerR family transcriptional regulator
HDHGJDOP_02639	6.77e-21	xkdG	-	-	S	-	-	-	Phage capsid family
HDHGJDOP_02640	1.25e-202	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HDHGJDOP_02641	1.02e-79	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDHGJDOP_02642	3.5e-47	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HDHGJDOP_02644	1.84e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
HDHGJDOP_02645	5.34e-280	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_02646	6.08e-105	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HDHGJDOP_02647	2.76e-120	-	-	-	S	-	-	-	DinB family
HDHGJDOP_02649	1.14e-187	supH	-	-	S	-	-	-	hydrolase
HDHGJDOP_02650	5.2e-93	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDHGJDOP_02651	7.33e-67	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDHGJDOP_02652	2.38e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDHGJDOP_02653	9.08e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDHGJDOP_02654	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_02655	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HDHGJDOP_02656	9.54e-229	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HDHGJDOP_02657	1.88e-106	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDHGJDOP_02658	5.33e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02659	1.32e-270	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_02660	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HDHGJDOP_02661	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HDHGJDOP_02662	3.67e-120	yrhH	-	-	Q	-	-	-	methyltransferase
HDHGJDOP_02663	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HDHGJDOP_02664	4.62e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HDHGJDOP_02665	1.48e-78	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HDHGJDOP_02666	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HDHGJDOP_02667	4.76e-106	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HDHGJDOP_02668	1.35e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
HDHGJDOP_02669	7.59e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDHGJDOP_02670	2.28e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HDHGJDOP_02671	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDHGJDOP_02672	1.4e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HDHGJDOP_02673	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HDHGJDOP_02674	8.77e-104	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HDHGJDOP_02675	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HDHGJDOP_02676	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDHGJDOP_02677	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDHGJDOP_02678	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HDHGJDOP_02679	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HDHGJDOP_02680	4.49e-151	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HDHGJDOP_02681	7.74e-257	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDHGJDOP_02682	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HDHGJDOP_02683	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDHGJDOP_02684	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDHGJDOP_02685	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDHGJDOP_02686	4.09e-231	yrrI	-	-	S	-	-	-	AI-2E family transporter
HDHGJDOP_02687	1.43e-164	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HDHGJDOP_02688	5.82e-185	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HDHGJDOP_02689	4.74e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDHGJDOP_02690	1.41e-134	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDHGJDOP_02691	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HDHGJDOP_02692	8.4e-42	yrzR	-	-	-	-	-	-	-
HDHGJDOP_02693	9e-101	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_02694	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDHGJDOP_02695	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HDHGJDOP_02696	8.02e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDHGJDOP_02697	2.35e-266	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HDHGJDOP_02698	3.74e-83	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02699	4.18e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HDHGJDOP_02700	1.68e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HDHGJDOP_02701	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HDHGJDOP_02702	7.9e-306	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HDHGJDOP_02705	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HDHGJDOP_02706	4.07e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDHGJDOP_02707	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDHGJDOP_02708	1.71e-116	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDHGJDOP_02709	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HDHGJDOP_02710	7.18e-59	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HDHGJDOP_02711	3.74e-104	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HDHGJDOP_02712	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HDHGJDOP_02713	2.26e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HDHGJDOP_02714	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_02715	1.16e-133	yrbG	-	-	S	-	-	-	membrane
HDHGJDOP_02716	3.7e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HDHGJDOP_02717	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HDHGJDOP_02718	9.18e-290	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDHGJDOP_02719	7.88e-244	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDHGJDOP_02720	3.4e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HDHGJDOP_02721	6.61e-232	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDHGJDOP_02722	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDHGJDOP_02723	1.16e-118	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HDHGJDOP_02725	8.39e-34	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_02726	1.61e-214	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HDHGJDOP_02727	4.89e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HDHGJDOP_02728	1.3e-180	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HDHGJDOP_02729	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HDHGJDOP_02730	8.23e-269	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HDHGJDOP_02731	1.49e-115	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HDHGJDOP_02732	4.34e-201	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HDHGJDOP_02733	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HDHGJDOP_02734	2.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDHGJDOP_02735	2.87e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HDHGJDOP_02736	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HDHGJDOP_02737	5.78e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HDHGJDOP_02738	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HDHGJDOP_02739	3.7e-199	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HDHGJDOP_02740	2.65e-177	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HDHGJDOP_02741	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HDHGJDOP_02742	1.61e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDHGJDOP_02743	3.98e-107	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HDHGJDOP_02744	2.51e-201	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDHGJDOP_02745	2.91e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HDHGJDOP_02746	1.19e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HDHGJDOP_02747	1.6e-128	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HDHGJDOP_02748	2.51e-192	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HDHGJDOP_02749	1.4e-159	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HDHGJDOP_02750	2.79e-293	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDHGJDOP_02751	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDHGJDOP_02752	3.61e-34	-	-	-	-	-	-	-	-
HDHGJDOP_02753	3.17e-234	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HDHGJDOP_02754	5.07e-232	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HDHGJDOP_02755	4.08e-306	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HDHGJDOP_02756	1.98e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HDHGJDOP_02757	4.99e-176	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HDHGJDOP_02758	6.05e-222	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HDHGJDOP_02759	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HDHGJDOP_02760	2.79e-311	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HDHGJDOP_02761	3.63e-110	ysxD	-	-	-	-	-	-	-
HDHGJDOP_02762	8.88e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDHGJDOP_02763	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HDHGJDOP_02764	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HDHGJDOP_02765	8.92e-291	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDHGJDOP_02766	2.43e-284	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDHGJDOP_02767	6.44e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HDHGJDOP_02768	1.04e-147	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDHGJDOP_02769	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDHGJDOP_02770	2.66e-249	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDHGJDOP_02771	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDHGJDOP_02772	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDHGJDOP_02773	1.45e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HDHGJDOP_02774	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HDHGJDOP_02779	1.78e-113	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDHGJDOP_02780	3.07e-129	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDHGJDOP_02781	2.38e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HDHGJDOP_02782	1.05e-253	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HDHGJDOP_02783	1.06e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDHGJDOP_02784	7.32e-95	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDHGJDOP_02785	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02786	8.26e-96	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HDHGJDOP_02787	1.77e-188	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HDHGJDOP_02788	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HDHGJDOP_02789	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HDHGJDOP_02790	9.97e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HDHGJDOP_02791	9.22e-270	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDHGJDOP_02792	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDHGJDOP_02793	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDHGJDOP_02794	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HDHGJDOP_02795	5.59e-224	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HDHGJDOP_02796	5.83e-176	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HDHGJDOP_02797	2.18e-172	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HDHGJDOP_02798	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02799	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDHGJDOP_02800	9.33e-150	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HDHGJDOP_02801	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HDHGJDOP_02802	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDHGJDOP_02803	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HDHGJDOP_02804	2.02e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HDHGJDOP_02805	4.23e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDHGJDOP_02806	1.64e-210	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDHGJDOP_02807	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDHGJDOP_02808	1.27e-248	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDHGJDOP_02809	1.94e-165	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDHGJDOP_02810	8.83e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HDHGJDOP_02811	5.97e-244	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HDHGJDOP_02812	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HDHGJDOP_02813	5e-309	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HDHGJDOP_02814	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HDHGJDOP_02815	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HDHGJDOP_02816	1.27e-186	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HDHGJDOP_02817	8.11e-211	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HDHGJDOP_02818	2.69e-312	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HDHGJDOP_02819	2.36e-269	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HDHGJDOP_02820	1.33e-175	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HDHGJDOP_02821	2.82e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HDHGJDOP_02822	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HDHGJDOP_02823	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HDHGJDOP_02824	4.34e-235	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HDHGJDOP_02825	1.52e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HDHGJDOP_02826	4.11e-82	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HDHGJDOP_02827	5.91e-51	ysdA	-	-	S	-	-	-	Membrane
HDHGJDOP_02828	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDHGJDOP_02829	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HDHGJDOP_02830	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDHGJDOP_02831	1.21e-144	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HDHGJDOP_02832	3.04e-64	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HDHGJDOP_02833	8.26e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HDHGJDOP_02834	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_02835	2.22e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HDHGJDOP_02836	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDHGJDOP_02837	6.12e-192	ytxC	-	-	S	-	-	-	YtxC-like family
HDHGJDOP_02838	2.03e-136	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HDHGJDOP_02839	2.64e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HDHGJDOP_02840	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HDHGJDOP_02841	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDHGJDOP_02842	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HDHGJDOP_02843	4.24e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDHGJDOP_02844	7.74e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02845	3.31e-251	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HDHGJDOP_02846	4.68e-198	ytbE	-	-	S	-	-	-	reductase
HDHGJDOP_02847	3.15e-123	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDHGJDOP_02848	4.52e-135	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HDHGJDOP_02849	2.14e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDHGJDOP_02850	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDHGJDOP_02851	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HDHGJDOP_02852	2.29e-164	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_02853	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HDHGJDOP_02854	1.54e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HDHGJDOP_02855	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HDHGJDOP_02856	1.14e-95	ytwI	-	-	S	-	-	-	membrane
HDHGJDOP_02857	8.18e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HDHGJDOP_02858	1.34e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HDHGJDOP_02859	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HDHGJDOP_02860	1.33e-228	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDHGJDOP_02861	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDHGJDOP_02862	2.08e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDHGJDOP_02863	1.92e-283	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HDHGJDOP_02864	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HDHGJDOP_02865	1.12e-71	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HDHGJDOP_02866	3.08e-113	ytrI	-	-	-	-	-	-	-
HDHGJDOP_02867	1.17e-30	-	-	-	-	-	-	-	-
HDHGJDOP_02868	7.37e-223	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HDHGJDOP_02869	3.44e-60	ytpI	-	-	S	-	-	-	YtpI-like protein
HDHGJDOP_02870	3.87e-303	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HDHGJDOP_02871	2.31e-163	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HDHGJDOP_02872	1.33e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_02874	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDHGJDOP_02875	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDHGJDOP_02876	1.64e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HDHGJDOP_02877	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDHGJDOP_02878	4.08e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HDHGJDOP_02879	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDHGJDOP_02880	1.37e-99	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HDHGJDOP_02881	3.61e-147	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HDHGJDOP_02882	1.31e-103	yteJ	-	-	S	-	-	-	RDD family
HDHGJDOP_02883	1.88e-227	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HDHGJDOP_02884	1.23e-191	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDHGJDOP_02885	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HDHGJDOP_02886	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDHGJDOP_02887	4.15e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HDHGJDOP_02888	1.06e-280	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDHGJDOP_02889	3.99e-259	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HDHGJDOP_02890	4.41e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDHGJDOP_02891	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDHGJDOP_02892	3.79e-183	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HDHGJDOP_02893	2.22e-137	yttP	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02894	2.38e-109	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HDHGJDOP_02895	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HDHGJDOP_02896	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDHGJDOP_02897	1.22e-272	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HDHGJDOP_02900	0.000125	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HDHGJDOP_02902	1.52e-161	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDHGJDOP_02903	6.5e-189	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDHGJDOP_02904	1.06e-188	-	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_02905	7.21e-154	ygaZ	-	-	E	-	-	-	AzlC protein
HDHGJDOP_02906	7.23e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDHGJDOP_02907	1.41e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDHGJDOP_02908	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDHGJDOP_02909	3.32e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HDHGJDOP_02910	9.68e-138	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDHGJDOP_02911	1.4e-283	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HDHGJDOP_02912	1.87e-127	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HDHGJDOP_02913	2.47e-184	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HDHGJDOP_02914	7.72e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HDHGJDOP_02915	1.8e-248	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HDHGJDOP_02916	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HDHGJDOP_02917	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HDHGJDOP_02918	2.16e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDHGJDOP_02919	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDHGJDOP_02920	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDHGJDOP_02921	1.15e-136	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDHGJDOP_02922	1.1e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HDHGJDOP_02923	2.23e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HDHGJDOP_02924	5.33e-98	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HDHGJDOP_02925	8.38e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HDHGJDOP_02926	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
HDHGJDOP_02927	1.43e-287	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HDHGJDOP_02928	2.98e-90	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HDHGJDOP_02929	1.41e-204	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HDHGJDOP_02930	4.34e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDHGJDOP_02931	4.54e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
HDHGJDOP_02932	3.42e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
HDHGJDOP_02933	1.86e-214	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDHGJDOP_02934	2.86e-198	ytlQ	-	-	-	-	-	-	-
HDHGJDOP_02935	2.04e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HDHGJDOP_02936	4.05e-214	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDHGJDOP_02937	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HDHGJDOP_02938	3.89e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDHGJDOP_02939	1.72e-251	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HDHGJDOP_02940	1.92e-149	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDHGJDOP_02941	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HDHGJDOP_02942	4.25e-160	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDHGJDOP_02943	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_02944	2.31e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HDHGJDOP_02945	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HDHGJDOP_02946	3.57e-35	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HDHGJDOP_02947	4.56e-153	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_02948	3.41e-296	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDHGJDOP_02949	6.99e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDHGJDOP_02950	1.37e-182	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HDHGJDOP_02951	2.49e-313	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HDHGJDOP_02952	6.31e-96	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_02953	8.6e-69	ytwF	-	-	P	-	-	-	Sulfurtransferase
HDHGJDOP_02954	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HDHGJDOP_02955	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HDHGJDOP_02956	1.79e-172	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HDHGJDOP_02957	2.16e-265	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HDHGJDOP_02958	4.62e-130	ywaF	-	-	S	-	-	-	Integral membrane protein
HDHGJDOP_02959	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HDHGJDOP_02960	7.67e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_02961	4.31e-206	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HDHGJDOP_02962	5.19e-157	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_02963	3.54e-258	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HDHGJDOP_02964	7.08e-160	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_02965	2.09e-190	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HDHGJDOP_02966	2.63e-203	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HDHGJDOP_02967	1.38e-170	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HDHGJDOP_02968	9.08e-202	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_02969	6.32e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HDHGJDOP_02971	2.89e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HDHGJDOP_02972	6.73e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HDHGJDOP_02973	4.07e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HDHGJDOP_02975	2.17e-266	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HDHGJDOP_02976	6.67e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HDHGJDOP_02977	7.46e-80	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HDHGJDOP_02978	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_02979	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDHGJDOP_02980	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDHGJDOP_02981	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HDHGJDOP_02982	1.65e-51	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HDHGJDOP_02983	6.15e-187	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HDHGJDOP_02984	6.07e-228	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HDHGJDOP_02985	1.38e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDHGJDOP_02986	3.42e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HDHGJDOP_02987	5.86e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HDHGJDOP_02988	1.67e-77	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HDHGJDOP_02989	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HDHGJDOP_02991	9.99e-98	ytkA	-	-	S	-	-	-	YtkA-like
HDHGJDOP_02992	5.89e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDHGJDOP_02993	5.71e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDHGJDOP_02994	4.26e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HDHGJDOP_02995	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HDHGJDOP_02996	6.36e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HDHGJDOP_02997	9.63e-230	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HDHGJDOP_02998	3.88e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HDHGJDOP_02999	4.21e-265	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HDHGJDOP_03000	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDHGJDOP_03001	7.22e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDHGJDOP_03002	2.39e-188	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HDHGJDOP_03003	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HDHGJDOP_03004	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HDHGJDOP_03005	8.57e-160	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HDHGJDOP_03006	5.18e-93	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HDHGJDOP_03030	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HDHGJDOP_03031	4.14e-117	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HDHGJDOP_03032	1.38e-273	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HDHGJDOP_03033	7.32e-105	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HDHGJDOP_03034	1.42e-102	yuaE	-	-	S	-	-	-	DinB superfamily
HDHGJDOP_03035	1.21e-134	-	-	-	S	-	-	-	MOSC domain
HDHGJDOP_03036	9.64e-288	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HDHGJDOP_03037	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDHGJDOP_03038	9.65e-119	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HDHGJDOP_03039	4.6e-119	yuaB	-	-	-	-	-	-	-
HDHGJDOP_03040	1.97e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HDHGJDOP_03041	2.27e-185	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDHGJDOP_03042	6.24e-268	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HDHGJDOP_03043	2.36e-47	-	-	-	G	-	-	-	Cupin
HDHGJDOP_03044	2.17e-57	yjcN	-	-	-	-	-	-	-
HDHGJDOP_03047	2.15e-177	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HDHGJDOP_03048	7.36e-20	-	-	-	-	-	-	-	-
HDHGJDOP_03053	9.14e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDHGJDOP_03055	4.3e-54	-	-	-	-	-	-	-	-
HDHGJDOP_03056	1.71e-304	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HDHGJDOP_03057	2.56e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HDHGJDOP_03058	2.74e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
HDHGJDOP_03060	2.05e-58	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HDHGJDOP_03061	1.64e-57	-	-	-	S	-	-	-	Bacteriophage holin family
HDHGJDOP_03064	3.63e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDHGJDOP_03065	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HDHGJDOP_03066	4.15e-125	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HDHGJDOP_03068	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HDHGJDOP_03073	4.74e-43	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDHGJDOP_03074	1.41e-26	-	-	-	S	-	-	-	Phage head-tail joining protein
HDHGJDOP_03076	6.72e-130	-	-	-	S	-	-	-	capsid protein
HDHGJDOP_03077	2.8e-68	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HDHGJDOP_03078	9.64e-183	-	-	-	S	-	-	-	portal protein
HDHGJDOP_03080	9.42e-163	terL	-	-	S	-	-	-	Terminase
HDHGJDOP_03081	4.47e-68	-	-	-	L	-	-	-	Terminase, small subunit
HDHGJDOP_03086	6.63e-10	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	COG1403 Restriction endonuclease
HDHGJDOP_03093	1.69e-65	-	-	-	K	-	-	-	BRO family, N-terminal domain
HDHGJDOP_03100	2.58e-72	-	-	-	L	-	-	-	Arm DNA-binding domain
HDHGJDOP_03102	7.33e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDHGJDOP_03103	2.73e-248	yubA	-	-	S	-	-	-	transporter activity
HDHGJDOP_03104	4.84e-231	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HDHGJDOP_03105	4.02e-126	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HDHGJDOP_03106	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HDHGJDOP_03107	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HDHGJDOP_03108	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HDHGJDOP_03109	4.49e-285	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HDHGJDOP_03110	1.68e-174	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HDHGJDOP_03111	1.82e-52	-	-	-	-	-	-	-	-
HDHGJDOP_03112	5.54e-236	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HDHGJDOP_03113	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HDHGJDOP_03114	1.82e-293	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HDHGJDOP_03115	1.95e-149	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HDHGJDOP_03116	3.56e-22	-	-	-	-	-	-	-	-
HDHGJDOP_03117	2.98e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HDHGJDOP_03118	8.97e-227	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HDHGJDOP_03119	4.57e-90	yugN	-	-	S	-	-	-	YugN-like family
HDHGJDOP_03121	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDHGJDOP_03122	8.85e-288	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HDHGJDOP_03123	7.5e-283	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HDHGJDOP_03124	1.28e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HDHGJDOP_03125	8.3e-82	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HDHGJDOP_03126	2.28e-264	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HDHGJDOP_03127	1.53e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03128	3.41e-192	yugF	-	-	I	-	-	-	Hydrolase
HDHGJDOP_03129	3.95e-51	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HDHGJDOP_03130	1.89e-276	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HDHGJDOP_03131	5e-278	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_03132	4.14e-81	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HDHGJDOP_03133	2.44e-147	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HDHGJDOP_03134	2.6e-240	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HDHGJDOP_03135	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HDHGJDOP_03136	5.95e-92	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03137	2.08e-97	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HDHGJDOP_03138	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HDHGJDOP_03139	3.8e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HDHGJDOP_03140	7.9e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HDHGJDOP_03141	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_03142	1.68e-232	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDHGJDOP_03143	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDHGJDOP_03145	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HDHGJDOP_03146	8.6e-88	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDHGJDOP_03147	1.42e-65	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDHGJDOP_03148	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDHGJDOP_03149	1.13e-97	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDHGJDOP_03150	2.15e-49	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDHGJDOP_03151	8.16e-77	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HDHGJDOP_03152	3.55e-77	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HDHGJDOP_03153	1.34e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDHGJDOP_03154	1.19e-315	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_03156	5.91e-78	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HDHGJDOP_03157	1.87e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HDHGJDOP_03158	1.59e-62	yuzC	-	-	-	-	-	-	-
HDHGJDOP_03159	1.12e-285	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HDHGJDOP_03160	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDHGJDOP_03161	4.46e-132	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HDHGJDOP_03162	4.96e-86	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDHGJDOP_03163	1.1e-50	yueH	-	-	S	-	-	-	YueH-like protein
HDHGJDOP_03164	4.3e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HDHGJDOP_03165	2.31e-232	yueF	-	-	S	-	-	-	transporter activity
HDHGJDOP_03166	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HDHGJDOP_03167	1.83e-123	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HDHGJDOP_03168	2.35e-159	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_03169	4.27e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HDHGJDOP_03170	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HDHGJDOP_03171	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDHGJDOP_03172	2.45e-261	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HDHGJDOP_03173	8.78e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HDHGJDOP_03174	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HDHGJDOP_03175	1.66e-288	yukF	-	-	QT	-	-	-	Transcriptional regulator
HDHGJDOP_03176	9.05e-258	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HDHGJDOP_03177	2.71e-165	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HDHGJDOP_03178	3.6e-42	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HDHGJDOP_03179	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_03180	5.68e-208	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HDHGJDOP_03181	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HDHGJDOP_03182	7.09e-273	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HDHGJDOP_03183	5.34e-166	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_03184	2.31e-198	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HDHGJDOP_03185	1.8e-152	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HDHGJDOP_03186	4.35e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HDHGJDOP_03187	1.11e-273	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HDHGJDOP_03188	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HDHGJDOP_03189	1.37e-98	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HDHGJDOP_03190	2.23e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03191	1.21e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
HDHGJDOP_03192	3.83e-297	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDHGJDOP_03193	1.15e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HDHGJDOP_03195	1.29e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDHGJDOP_03196	1.57e-37	-	-	-	-	-	-	-	-
HDHGJDOP_03197	1.09e-86	-	-	-	CP	-	-	-	Membrane
HDHGJDOP_03198	1.41e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDHGJDOP_03200	1.12e-37	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HDHGJDOP_03202	5.08e-55	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HDHGJDOP_03203	6e-167	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_03204	1.88e-80	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HDHGJDOP_03205	1.46e-203	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDHGJDOP_03206	2.57e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDHGJDOP_03207	1.61e-48	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HDHGJDOP_03208	7.79e-262	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDHGJDOP_03209	2.61e-70	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03210	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HDHGJDOP_03211	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HDHGJDOP_03212	5.32e-72	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HDHGJDOP_03213	2.22e-206	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDHGJDOP_03214	3.65e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HDHGJDOP_03215	1.37e-306	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDHGJDOP_03216	5.56e-244	yutH	-	-	S	-	-	-	Spore coat protein
HDHGJDOP_03217	1.07e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HDHGJDOP_03218	1.18e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDHGJDOP_03219	3e-93	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HDHGJDOP_03220	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03221	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HDHGJDOP_03222	1.26e-245	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HDHGJDOP_03223	1.53e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HDHGJDOP_03224	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDHGJDOP_03225	5.58e-182	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDHGJDOP_03226	7.05e-215	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HDHGJDOP_03227	2.23e-73	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HDHGJDOP_03228	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HDHGJDOP_03229	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HDHGJDOP_03230	6.3e-86	-	-	-	-	-	-	-	-
HDHGJDOP_03231	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_03232	2.55e-287	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HDHGJDOP_03233	7.27e-285	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HDHGJDOP_03234	1.11e-207	bsn	-	-	L	-	-	-	Ribonuclease
HDHGJDOP_03235	1.49e-252	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_03236	8.02e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HDHGJDOP_03237	6.94e-202	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HDHGJDOP_03238	2.91e-199	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HDHGJDOP_03239	7.16e-201	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDHGJDOP_03240	4.58e-305	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HDHGJDOP_03241	8.37e-232	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HDHGJDOP_03242	8.02e-204	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDHGJDOP_03244	1.34e-95	-	-	-	-	-	-	-	-
HDHGJDOP_03245	1.96e-27	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HDHGJDOP_03247	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HDHGJDOP_03248	2.19e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HDHGJDOP_03249	1.09e-128	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HDHGJDOP_03250	7.45e-94	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HDHGJDOP_03251	1.06e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HDHGJDOP_03252	2.79e-14	-	-	-	-	-	-	-	-
HDHGJDOP_03253	3.22e-63	-	-	-	-	-	-	-	-
HDHGJDOP_03255	5.17e-88	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_03256	7.85e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HDHGJDOP_03259	1.12e-188	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HDHGJDOP_03260	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HDHGJDOP_03261	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HDHGJDOP_03262	5.64e-150	-	-	-	S	-	-	-	Phage tail protein
HDHGJDOP_03263	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HDHGJDOP_03265	1.62e-42	-	-	-	S	-	-	-	Phage tail tube protein
HDHGJDOP_03267	2.31e-46	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDHGJDOP_03268	1.05e-40	-	-	-	S	-	-	-	Phage head-tail joining protein
HDHGJDOP_03269	5.7e-11	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDHGJDOP_03270	2.56e-32	-	-	-	-	-	-	-	-
HDHGJDOP_03271	4.2e-161	-	-	-	S	-	-	-	capsid protein
HDHGJDOP_03272	1.69e-95	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HDHGJDOP_03273	8.49e-220	-	-	-	S	-	-	-	portal protein
HDHGJDOP_03275	0.0	terL	-	-	S	-	-	-	Terminase
HDHGJDOP_03276	4.02e-79	-	-	-	L	-	-	-	Terminase, small subunit
HDHGJDOP_03278	4.27e-64	-	-	-	-	-	-	-	-
HDHGJDOP_03279	2.16e-287	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
HDHGJDOP_03280	1.19e-20	-	-	-	S	-	-	-	VRR-NUC domain protein
HDHGJDOP_03281	0.0	-	-	-	L	-	-	-	Virulence-associated protein E
HDHGJDOP_03283	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase A domain
HDHGJDOP_03284	1.89e-08	-	-	-	-	-	-	-	-
HDHGJDOP_03285	5.24e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HDHGJDOP_03287	4.06e-204	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HDHGJDOP_03288	5.63e-16	-	-	-	-	-	-	-	-
HDHGJDOP_03289	1.52e-58	-	-	-	-	-	-	-	-
HDHGJDOP_03291	1.14e-44	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HDHGJDOP_03293	1.05e-40	-	-	-	-	-	-	-	-
HDHGJDOP_03294	2.73e-26	-	-	-	-	-	-	-	-
HDHGJDOP_03295	3.84e-70	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDHGJDOP_03296	1.98e-70	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HDHGJDOP_03297	3.02e-191	-	-	-	S	-	-	-	Pfam:Arm-DNA-bind_4
HDHGJDOP_03298	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HDHGJDOP_03299	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HDHGJDOP_03300	3.01e-294	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDHGJDOP_03301	1.75e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HDHGJDOP_03302	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HDHGJDOP_03304	2.97e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDHGJDOP_03305	2.88e-183	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HDHGJDOP_03306	3.3e-135	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HDHGJDOP_03307	1.51e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDHGJDOP_03308	5.08e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HDHGJDOP_03309	2.25e-70	yusE	-	-	CO	-	-	-	Thioredoxin
HDHGJDOP_03310	5.93e-30	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HDHGJDOP_03311	2.99e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HDHGJDOP_03312	1.19e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HDHGJDOP_03313	4.13e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HDHGJDOP_03314	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HDHGJDOP_03315	3.02e-275	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HDHGJDOP_03316	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HDHGJDOP_03317	1.72e-10	-	-	-	S	-	-	-	YuzL-like protein
HDHGJDOP_03318	6.69e-209	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HDHGJDOP_03319	7.03e-53	-	-	-	-	-	-	-	-
HDHGJDOP_03320	3.53e-69	yusN	-	-	M	-	-	-	Coat F domain
HDHGJDOP_03321	1.47e-86	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HDHGJDOP_03322	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HDHGJDOP_03323	6.56e-74	-	-	-	L	-	-	-	PFAM Restriction endonuclease BamHI
HDHGJDOP_03324	1.48e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDHGJDOP_03325	3.73e-159	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HDHGJDOP_03326	1.46e-50	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HDHGJDOP_03327	1.06e-191	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDHGJDOP_03328	2.79e-62	-	-	-	S	-	-	-	YusW-like protein
HDHGJDOP_03329	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HDHGJDOP_03330	1.77e-177	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_03331	5.63e-101	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HDHGJDOP_03332	8.65e-295	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDHGJDOP_03333	2.06e-160	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_03334	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_03335	2.68e-32	-	-	-	-	-	-	-	-
HDHGJDOP_03336	6.7e-196	yuxN	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03337	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDHGJDOP_03338	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HDHGJDOP_03339	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HDHGJDOP_03340	3e-235	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HDHGJDOP_03341	9.22e-248	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HDHGJDOP_03342	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDHGJDOP_03343	2.86e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_03344	6.74e-159	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HDHGJDOP_03345	1.33e-165	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HDHGJDOP_03346	6e-128	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HDHGJDOP_03347	7.39e-65	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HDHGJDOP_03348	9.45e-281	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_03349	3.89e-125	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HDHGJDOP_03350	5.35e-257	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HDHGJDOP_03351	5.73e-224	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_03352	1.07e-211	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDHGJDOP_03353	4.79e-178	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_03354	2.36e-213	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HDHGJDOP_03355	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HDHGJDOP_03356	4.48e-171	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_03357	1.14e-48	-	-	-	-	-	-	-	-
HDHGJDOP_03358	1.47e-130	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HDHGJDOP_03359	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
HDHGJDOP_03360	9.98e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HDHGJDOP_03361	1.37e-78	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HDHGJDOP_03362	6.61e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDHGJDOP_03363	9.44e-217	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_03364	6.08e-234	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_03365	5e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDHGJDOP_03366	2.17e-153	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HDHGJDOP_03367	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HDHGJDOP_03368	4.34e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HDHGJDOP_03369	2.04e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HDHGJDOP_03370	3.8e-210	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HDHGJDOP_03371	2.24e-203	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HDHGJDOP_03372	8.02e-204	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HDHGJDOP_03373	4.92e-174	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HDHGJDOP_03374	4.14e-118	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HDHGJDOP_03375	4.14e-146	yfiK	-	-	K	-	-	-	Regulator
HDHGJDOP_03376	3.01e-237	-	-	-	T	-	-	-	Histidine kinase
HDHGJDOP_03377	1.12e-216	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HDHGJDOP_03378	3.65e-235	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDHGJDOP_03379	1.44e-229	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HDHGJDOP_03380	1.77e-200	yvgN	-	-	S	-	-	-	reductase
HDHGJDOP_03381	1.55e-110	yvgO	-	-	-	-	-	-	-
HDHGJDOP_03382	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HDHGJDOP_03383	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HDHGJDOP_03384	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HDHGJDOP_03385	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDHGJDOP_03387	6.1e-128	yvgT	-	-	S	-	-	-	membrane
HDHGJDOP_03388	5.24e-188	-	-	-	S	-	-	-	Metallo-peptidase family M12
HDHGJDOP_03389	5.06e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HDHGJDOP_03390	2.51e-135	bdbD	-	-	O	-	-	-	Thioredoxin
HDHGJDOP_03391	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HDHGJDOP_03392	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDHGJDOP_03393	9.29e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HDHGJDOP_03394	8.06e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HDHGJDOP_03395	4.69e-238	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HDHGJDOP_03396	1.03e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDHGJDOP_03397	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_03398	1.97e-59	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HDHGJDOP_03399	1.43e-225	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_03400	3.93e-175	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HDHGJDOP_03401	5.33e-152	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDHGJDOP_03402	1.35e-152	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDHGJDOP_03403	1.8e-181	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HDHGJDOP_03404	3.28e-167	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HDHGJDOP_03405	5.25e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDHGJDOP_03406	4.27e-201	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HDHGJDOP_03407	9.27e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHGJDOP_03408	9.41e-56	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HDHGJDOP_03410	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HDHGJDOP_03411	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDHGJDOP_03412	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HDHGJDOP_03413	9.24e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HDHGJDOP_03414	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HDHGJDOP_03415	1.07e-89	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HDHGJDOP_03416	1.09e-90	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HDHGJDOP_03417	1.17e-67	yvaP	-	-	K	-	-	-	transcriptional
HDHGJDOP_03418	3.51e-308	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HDHGJDOP_03419	7.17e-154	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HDHGJDOP_03420	4.95e-170	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HDHGJDOP_03421	1.91e-154	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HDHGJDOP_03422	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_03423	1.41e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HDHGJDOP_03424	5.17e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDHGJDOP_03425	7.36e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HDHGJDOP_03426	1.25e-262	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDHGJDOP_03427	3.5e-108	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HDHGJDOP_03428	2.95e-139	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HDHGJDOP_03429	2.99e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDHGJDOP_03430	5.4e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HDHGJDOP_03431	1.21e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDHGJDOP_03432	2.67e-125	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HDHGJDOP_03433	1.55e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HDHGJDOP_03434	2.61e-148	yvbI	-	-	M	-	-	-	Membrane
HDHGJDOP_03435	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDHGJDOP_03436	5.07e-103	yvbK	-	-	K	-	-	-	acetyltransferase
HDHGJDOP_03437	4.16e-260	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDHGJDOP_03438	1.87e-219	-	-	-	-	-	-	-	-
HDHGJDOP_03439	3.54e-159	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HDHGJDOP_03440	1.13e-182	-	-	-	C	-	-	-	WbqC-like protein family
HDHGJDOP_03441	2.49e-179	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HDHGJDOP_03442	6.62e-279	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HDHGJDOP_03443	6.48e-215	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HDHGJDOP_03444	2.68e-275	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HDHGJDOP_03445	9.36e-317	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDHGJDOP_03446	2.83e-286	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HDHGJDOP_03447	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDHGJDOP_03448	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HDHGJDOP_03449	1.49e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDHGJDOP_03450	1.55e-274	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HDHGJDOP_03451	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDHGJDOP_03452	1.91e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDHGJDOP_03454	4.6e-272	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDHGJDOP_03455	1.76e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HDHGJDOP_03456	1.78e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_03457	3.86e-18	yvbU	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03458	2.18e-124	yvbU	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03459	5.35e-196	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HDHGJDOP_03460	6.69e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_03462	2.88e-190	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HDHGJDOP_03463	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HDHGJDOP_03464	3.08e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HDHGJDOP_03465	3.12e-167	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDHGJDOP_03466	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HDHGJDOP_03467	1.69e-170	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDHGJDOP_03468	2.07e-264	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDHGJDOP_03469	1.16e-151	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HDHGJDOP_03470	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HDHGJDOP_03471	1.88e-292	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HDHGJDOP_03472	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HDHGJDOP_03473	2.77e-224	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HDHGJDOP_03474	2.79e-275	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HDHGJDOP_03475	1.28e-70	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HDHGJDOP_03476	2.7e-131	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDHGJDOP_03477	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_03478	1.99e-238	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHGJDOP_03479	6.55e-251	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HDHGJDOP_03480	6.01e-245	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HDHGJDOP_03481	6.38e-258	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HDHGJDOP_03482	1.95e-253	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDHGJDOP_03483	3.44e-200	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHGJDOP_03484	3.48e-268	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HDHGJDOP_03485	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HDHGJDOP_03486	4.44e-151	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HDHGJDOP_03487	4.37e-151	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HDHGJDOP_03488	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HDHGJDOP_03489	8.66e-312	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HDHGJDOP_03491	8.3e-111	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HDHGJDOP_03492	4.2e-164	-	-	-	CH	-	-	-	FAD binding domain
HDHGJDOP_03493	2.74e-98	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HDHGJDOP_03494	5.22e-137	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HDHGJDOP_03495	3.65e-108	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDHGJDOP_03496	7.09e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HDHGJDOP_03497	1.25e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HDHGJDOP_03498	3.4e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HDHGJDOP_03499	1.63e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HDHGJDOP_03500	6.57e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HDHGJDOP_03501	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HDHGJDOP_03502	3.08e-44	-	-	-	-	-	-	-	-
HDHGJDOP_03504	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDHGJDOP_03505	5.05e-279	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HDHGJDOP_03506	2.68e-226	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HDHGJDOP_03507	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDHGJDOP_03508	1.4e-202	yraN	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03509	3.16e-258	yraM	-	-	S	-	-	-	PrpF protein
HDHGJDOP_03510	6.64e-313	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HDHGJDOP_03511	1.06e-110	-	-	-	-	-	-	-	-
HDHGJDOP_03512	2.87e-132	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HDHGJDOP_03513	5.98e-66	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HDHGJDOP_03514	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HDHGJDOP_03515	1.42e-133	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HDHGJDOP_03516	7.72e-229	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDHGJDOP_03517	4.11e-100	-	-	-	M	-	-	-	Ribonuclease
HDHGJDOP_03518	5.8e-167	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HDHGJDOP_03519	6.52e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HDHGJDOP_03520	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDHGJDOP_03521	3.01e-224	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HDHGJDOP_03522	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDHGJDOP_03523	7.32e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDHGJDOP_03524	6.06e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDHGJDOP_03525	7.8e-192	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HDHGJDOP_03526	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HDHGJDOP_03527	1.01e-231	sasA	-	-	T	-	-	-	Histidine kinase
HDHGJDOP_03528	1.49e-153	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_03529	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDHGJDOP_03530	8.74e-139	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HDHGJDOP_03531	4.63e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDHGJDOP_03532	6.02e-163	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDHGJDOP_03533	1.75e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDHGJDOP_03534	6.49e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HDHGJDOP_03535	4.77e-279	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDHGJDOP_03536	1.45e-145	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDHGJDOP_03537	8.64e-258	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDHGJDOP_03538	3.83e-173	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HDHGJDOP_03539	1.2e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HDHGJDOP_03540	3.18e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HDHGJDOP_03541	5.06e-193	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDHGJDOP_03542	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDHGJDOP_03543	2.47e-272	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDHGJDOP_03544	1.44e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDHGJDOP_03545	2.9e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HDHGJDOP_03546	6.76e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HDHGJDOP_03547	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HDHGJDOP_03548	1.09e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HDHGJDOP_03549	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDHGJDOP_03550	4.14e-214	yvlB	-	-	S	-	-	-	Putative adhesin
HDHGJDOP_03551	1.79e-61	yvlA	-	-	-	-	-	-	-
HDHGJDOP_03552	1.29e-40	yvkN	-	-	-	-	-	-	-
HDHGJDOP_03553	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDHGJDOP_03554	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDHGJDOP_03555	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03556	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HDHGJDOP_03557	1.12e-119	yvkB	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03558	3.49e-290	yvkA	-	-	P	-	-	-	-transporter
HDHGJDOP_03561	1.39e-278	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDHGJDOP_03562	5.83e-72	swrA	-	-	S	-	-	-	Swarming motility protein
HDHGJDOP_03563	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDHGJDOP_03564	1.35e-271	ywoF	-	-	P	-	-	-	Right handed beta helix region
HDHGJDOP_03565	1.48e-196	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDHGJDOP_03566	3.53e-158	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HDHGJDOP_03567	1.47e-58	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HDHGJDOP_03568	5.39e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_03569	1.08e-222	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDHGJDOP_03570	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDHGJDOP_03571	4.25e-130	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDHGJDOP_03572	1.92e-89	-	-	-	-	-	-	-	-
HDHGJDOP_03573	1.57e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HDHGJDOP_03574	2.18e-83	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HDHGJDOP_03575	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HDHGJDOP_03576	9.98e-154	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HDHGJDOP_03577	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HDHGJDOP_03578	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HDHGJDOP_03579	1.27e-104	yviE	-	-	-	-	-	-	-
HDHGJDOP_03580	1.63e-206	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HDHGJDOP_03581	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HDHGJDOP_03582	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
HDHGJDOP_03583	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HDHGJDOP_03584	6.15e-95	yvyF	-	-	S	-	-	-	flagellar protein
HDHGJDOP_03585	4.91e-79	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HDHGJDOP_03586	2.93e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HDHGJDOP_03587	5.41e-316	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HDHGJDOP_03588	3.16e-197	degV	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03589	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDHGJDOP_03590	2.31e-245	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HDHGJDOP_03591	1.1e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HDHGJDOP_03592	9.24e-234	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03593	8.94e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HDHGJDOP_03594	4.55e-285	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HDHGJDOP_03595	2.22e-182	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HDHGJDOP_03596	8.08e-138	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HDHGJDOP_03597	8.4e-317	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HDHGJDOP_03598	5.86e-310	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDHGJDOP_03599	2.76e-270	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HDHGJDOP_03600	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDHGJDOP_03601	8.51e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDHGJDOP_03602	4.43e-268	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HDHGJDOP_03603	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HDHGJDOP_03604	1.99e-39	-	-	-	-	-	-	-	-
HDHGJDOP_03605	1.15e-179	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HDHGJDOP_03606	8.48e-235	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDHGJDOP_03607	2.14e-200	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDHGJDOP_03608	1.55e-241	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDHGJDOP_03609	7.77e-174	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HDHGJDOP_03610	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDHGJDOP_03611	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
HDHGJDOP_03612	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HDHGJDOP_03613	6.85e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDHGJDOP_03614	5.65e-258	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDHGJDOP_03615	2.3e-290	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDHGJDOP_03616	9.82e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDHGJDOP_03617	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HDHGJDOP_03618	2.94e-243	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HDHGJDOP_03619	3.1e-218	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HDHGJDOP_03620	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HDHGJDOP_03621	9.98e-304	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDHGJDOP_03622	2.02e-223	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03623	1.33e-195	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HDHGJDOP_03624	1.4e-60	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HDHGJDOP_03625	1.37e-288	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDHGJDOP_03626	1.16e-28	ywtC	-	-	-	-	-	-	-
HDHGJDOP_03627	7.41e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HDHGJDOP_03628	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HDHGJDOP_03629	8.45e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HDHGJDOP_03630	1.63e-244	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HDHGJDOP_03631	6.95e-228	-	-	-	E	-	-	-	Spore germination protein
HDHGJDOP_03632	3.22e-63	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HDHGJDOP_03633	4.74e-144	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HDHGJDOP_03634	1.08e-221	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HDHGJDOP_03635	2.47e-195	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDHGJDOP_03636	3.79e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDHGJDOP_03637	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HDHGJDOP_03638	7.29e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDHGJDOP_03639	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HDHGJDOP_03640	6.3e-111	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HDHGJDOP_03641	2.39e-115	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HDHGJDOP_03642	3.56e-185	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HDHGJDOP_03643	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HDHGJDOP_03644	5.73e-210	alsR	-	-	K	-	-	-	LysR substrate binding domain
HDHGJDOP_03645	5.9e-297	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDHGJDOP_03646	8.96e-150	ywrJ	-	-	-	-	-	-	-
HDHGJDOP_03647	4.38e-157	cotB	-	-	-	ko:K06325	-	ko00000	-
HDHGJDOP_03648	9.11e-261	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HDHGJDOP_03649	3.88e-09	-	-	-	-	-	-	-	-
HDHGJDOP_03650	4.7e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HDHGJDOP_03652	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HDHGJDOP_03653	3.97e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HDHGJDOP_03654	7.48e-126	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HDHGJDOP_03655	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HDHGJDOP_03656	1.29e-130	-	-	-	-	-	-	-	-
HDHGJDOP_03657	7.15e-83	-	-	-	-	-	-	-	-
HDHGJDOP_03658	3.77e-97	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
HDHGJDOP_03659	1.92e-25	-	-	-	-	-	-	-	-
HDHGJDOP_03660	2.19e-75	-	-	-	S	-	-	-	SUKH-4 immunity protein
HDHGJDOP_03661	2.69e-288	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HDHGJDOP_03662	1.36e-48	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HDHGJDOP_03664	3.03e-183	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HDHGJDOP_03665	2.45e-304	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDHGJDOP_03666	4.63e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HDHGJDOP_03667	3.37e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HDHGJDOP_03668	8.45e-144	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HDHGJDOP_03669	3e-22	-	-	-	-	-	-	-	-
HDHGJDOP_03670	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HDHGJDOP_03671	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDHGJDOP_03672	1.28e-193	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HDHGJDOP_03673	5.39e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDHGJDOP_03674	4.94e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HDHGJDOP_03675	1.83e-74	ywpG	-	-	-	-	-	-	-
HDHGJDOP_03676	1.79e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
HDHGJDOP_03677	2.54e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDHGJDOP_03678	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDHGJDOP_03679	4.41e-247	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HDHGJDOP_03680	5.1e-176	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HDHGJDOP_03681	1.16e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HDHGJDOP_03682	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HDHGJDOP_03683	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HDHGJDOP_03684	5.3e-93	ywoH	-	-	K	-	-	-	transcriptional
HDHGJDOP_03685	3.92e-270	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HDHGJDOP_03686	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HDHGJDOP_03687	1.81e-308	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HDHGJDOP_03688	2.1e-128	yjgF	-	-	Q	-	-	-	Isochorismatase family
HDHGJDOP_03689	3.63e-289	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HDHGJDOP_03690	1.51e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HDHGJDOP_03691	1.11e-262	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDHGJDOP_03692	5.56e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HDHGJDOP_03693	3.41e-88	ywnJ	-	-	S	-	-	-	VanZ like family
HDHGJDOP_03694	1.67e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HDHGJDOP_03695	7.6e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HDHGJDOP_03697	2.45e-88	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HDHGJDOP_03698	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDHGJDOP_03699	1.12e-21	yqgA	-	-	-	-	-	-	-
HDHGJDOP_03700	1.33e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HDHGJDOP_03701	3.75e-116	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HDHGJDOP_03702	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03703	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HDHGJDOP_03704	4.37e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HDHGJDOP_03705	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HDHGJDOP_03706	2.41e-16	csbD	-	-	K	-	-	-	CsbD-like
HDHGJDOP_03707	1.17e-243	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDHGJDOP_03708	2.91e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HDHGJDOP_03710	2.79e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HDHGJDOP_03711	4.74e-145	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HDHGJDOP_03712	6.86e-232	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HDHGJDOP_03713	1.85e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDHGJDOP_03714	1.27e-169	ywmB	-	-	S	-	-	-	TATA-box binding
HDHGJDOP_03715	1.85e-44	ywzB	-	-	S	-	-	-	membrane
HDHGJDOP_03716	1.98e-115	ywmA	-	-	-	-	-	-	-
HDHGJDOP_03717	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDHGJDOP_03718	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDHGJDOP_03719	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDHGJDOP_03720	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDHGJDOP_03721	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDHGJDOP_03722	3.35e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDHGJDOP_03723	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDHGJDOP_03724	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDHGJDOP_03725	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HDHGJDOP_03726	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDHGJDOP_03727	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDHGJDOP_03728	3.53e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HDHGJDOP_03729	9.2e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HDHGJDOP_03730	1.84e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDHGJDOP_03731	1.86e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HDHGJDOP_03732	1.34e-237	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDHGJDOP_03733	6.75e-96	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HDHGJDOP_03734	7.05e-148	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HDHGJDOP_03735	4.04e-77	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HDHGJDOP_03737	1.18e-194	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDHGJDOP_03738	8.38e-240	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDHGJDOP_03739	6.91e-84	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_03740	2.52e-115	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HDHGJDOP_03741	6.87e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDHGJDOP_03742	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HDHGJDOP_03743	3.09e-129	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDHGJDOP_03744	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HDHGJDOP_03745	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDHGJDOP_03746	6.51e-221	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HDHGJDOP_03747	1.59e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDHGJDOP_03748	3.69e-143	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDHGJDOP_03749	4.53e-203	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HDHGJDOP_03750	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HDHGJDOP_03751	1.84e-117	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HDHGJDOP_03752	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDHGJDOP_03753	1.53e-71	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDHGJDOP_03754	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HDHGJDOP_03755	1.51e-263	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HDHGJDOP_03756	5.39e-224	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HDHGJDOP_03757	3.23e-58	ywjC	-	-	-	-	-	-	-
HDHGJDOP_03758	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDHGJDOP_03759	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDHGJDOP_03760	1.61e-149	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HDHGJDOP_03761	1.07e-110	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HDHGJDOP_03762	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HDHGJDOP_03763	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDHGJDOP_03764	8.63e-102	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HDHGJDOP_03765	8.59e-162	ywiC	-	-	S	-	-	-	YwiC-like protein
HDHGJDOP_03766	2.74e-113	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HDHGJDOP_03767	7.56e-267	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HDHGJDOP_03768	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDHGJDOP_03769	4.46e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_03771	8.63e-110	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HDHGJDOP_03772	2.22e-123	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HDHGJDOP_03773	3.16e-102	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HDHGJDOP_03775	2.87e-213	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HDHGJDOP_03776	6.45e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HDHGJDOP_03777	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDHGJDOP_03778	1.96e-93	-	-	-	-	-	-	-	-
HDHGJDOP_03779	2.07e-116	ywhD	-	-	S	-	-	-	YwhD family
HDHGJDOP_03780	1.29e-151	ywhC	-	-	S	-	-	-	Peptidase family M50
HDHGJDOP_03781	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HDHGJDOP_03782	3.29e-90	ywhA	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03783	4.79e-307	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HDHGJDOP_03784	1.37e-113	ywgA	-	-	-	ko:K09388	-	ko00000	-
HDHGJDOP_03785	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HDHGJDOP_03786	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HDHGJDOP_03787	3.27e-136	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HDHGJDOP_03788	4.41e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HDHGJDOP_03789	2.51e-109	-	-	-	S	-	-	-	membrane
HDHGJDOP_03790	1.93e-194	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_03791	2.13e-208	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HDHGJDOP_03794	4.4e-208	-	-	-	-	-	-	-	-
HDHGJDOP_03796	8.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HDHGJDOP_03797	1.33e-199	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HDHGJDOP_03798	9.29e-207	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HDHGJDOP_03799	2.27e-222	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HDHGJDOP_03800	6.64e-185	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HDHGJDOP_03801	2.37e-20	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDHGJDOP_03803	6.08e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HDHGJDOP_03804	5.35e-289	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HDHGJDOP_03805	2.33e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HDHGJDOP_03806	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HDHGJDOP_03807	2.21e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_03808	1.63e-174	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HDHGJDOP_03809	4.05e-87	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HDHGJDOP_03810	8.02e-277	ywfA	-	-	EGP	-	-	-	-transporter
HDHGJDOP_03811	4.86e-249	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HDHGJDOP_03812	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDHGJDOP_03813	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HDHGJDOP_03814	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDHGJDOP_03815	8.64e-312	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDHGJDOP_03816	4.02e-80	-	-	-	-	-	-	-	-
HDHGJDOP_03817	2.6e-109	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HDHGJDOP_03818	3.3e-199	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDHGJDOP_03819	5.41e-226	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDHGJDOP_03820	2.9e-170	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDHGJDOP_03821	3.01e-212	spsG	-	-	M	-	-	-	Spore Coat
HDHGJDOP_03822	5.52e-160	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HDHGJDOP_03823	2.97e-266	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HDHGJDOP_03824	6.34e-195	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HDHGJDOP_03825	2.58e-275	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HDHGJDOP_03826	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HDHGJDOP_03827	4.13e-180	spsA	-	-	M	-	-	-	Spore Coat
HDHGJDOP_03828	1.29e-83	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HDHGJDOP_03829	4.39e-76	ywdK	-	-	S	-	-	-	small membrane protein
HDHGJDOP_03830	3.47e-287	ywdJ	-	-	F	-	-	-	Xanthine uracil
HDHGJDOP_03831	2.73e-56	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HDHGJDOP_03832	2.42e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDHGJDOP_03833	1.44e-186	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HDHGJDOP_03835	2.79e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDHGJDOP_03836	6.09e-27	ywdA	-	-	-	-	-	-	-
HDHGJDOP_03837	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDHGJDOP_03838	9.04e-317	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_03839	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HDHGJDOP_03841	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDHGJDOP_03842	1.83e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDHGJDOP_03843	1.26e-150	-	-	-	K	-	-	-	WYL domain
HDHGJDOP_03844	4.96e-161	ucpA	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDHGJDOP_03845	4.61e-56	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
HDHGJDOP_03846	1.36e-39	-	-	-	S	-	-	-	PFAM Stress responsive alpha-beta barrel
HDHGJDOP_03847	1.1e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HDHGJDOP_03848	1.84e-262	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDHGJDOP_03849	1.68e-87	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HDHGJDOP_03850	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HDHGJDOP_03851	1.08e-80	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HDHGJDOP_03852	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HDHGJDOP_03853	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDHGJDOP_03854	3.01e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HDHGJDOP_03855	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HDHGJDOP_03856	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HDHGJDOP_03857	1.52e-265	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDHGJDOP_03858	7.8e-78	gtcA	-	-	S	-	-	-	GtrA-like protein
HDHGJDOP_03859	1.72e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDHGJDOP_03861	6.64e-162	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HDHGJDOP_03862	4.83e-154	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HDHGJDOP_03863	5.52e-139	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HDHGJDOP_03864	9.8e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HDHGJDOP_03865	5.83e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HDHGJDOP_03866	2.41e-246	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HDHGJDOP_03867	2.72e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDHGJDOP_03868	9.98e-164	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDHGJDOP_03869	2.29e-200	ywbI	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_03870	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HDHGJDOP_03871	6.2e-142	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HDHGJDOP_03872	1.52e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HDHGJDOP_03873	2.16e-164	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HDHGJDOP_03874	1.97e-200	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HDHGJDOP_03875	4.69e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HDHGJDOP_03876	1.24e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HDHGJDOP_03877	8.3e-309	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHGJDOP_03878	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDHGJDOP_03879	2.87e-205	gspA	-	-	M	-	-	-	General stress
HDHGJDOP_03881	2.16e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HDHGJDOP_03882	7.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HDHGJDOP_03883	3.51e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HDHGJDOP_03884	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_03885	2.45e-289	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HDHGJDOP_03886	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHGJDOP_03887	3.02e-244	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDHGJDOP_03888	1.29e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDHGJDOP_03889	2.82e-315	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDHGJDOP_03890	1.89e-64	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_03891	4.85e-312	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHGJDOP_03892	3.67e-65	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HDHGJDOP_03893	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HDHGJDOP_03894	4.07e-139	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HDHGJDOP_03895	6.1e-216	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_03896	9.33e-229	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDHGJDOP_03897	8.85e-212	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HDHGJDOP_03898	1.06e-66	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HDHGJDOP_03899	1.16e-286	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDHGJDOP_03900	1.35e-58	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_03901	1.26e-62	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_03902	1.84e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHGJDOP_03903	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDHGJDOP_03904	7.52e-206	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HDHGJDOP_03905	1.05e-227	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDHGJDOP_03906	3.3e-261	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HDHGJDOP_03907	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HDHGJDOP_03908	1.26e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HDHGJDOP_03909	2.06e-313	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HDHGJDOP_03910	7.18e-140	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDHGJDOP_03911	6.72e-37	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDHGJDOP_03912	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HDHGJDOP_03913	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HDHGJDOP_03914	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HDHGJDOP_03915	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HDHGJDOP_03916	1.02e-283	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HDHGJDOP_03917	2.39e-191	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HDHGJDOP_03918	3.56e-259	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDHGJDOP_03919	1.49e-198	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HDHGJDOP_03920	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDHGJDOP_03922	5.75e-115	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HDHGJDOP_03923	7.02e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDHGJDOP_03924	5.24e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HDHGJDOP_03927	3.81e-105	yxjI	-	-	S	-	-	-	LURP-one-related
HDHGJDOP_03928	8.25e-271	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HDHGJDOP_03929	2.83e-185	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HDHGJDOP_03930	2.49e-262	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDHGJDOP_03931	1.64e-113	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HDHGJDOP_03932	3.23e-60	yxiS	-	-	-	-	-	-	-
HDHGJDOP_03933	3.04e-221	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HDHGJDOP_03934	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HDHGJDOP_03935	2.74e-227	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HDHGJDOP_03936	9.73e-176	bglS	-	-	M	-	-	-	licheninase activity
HDHGJDOP_03937	2.11e-183	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HDHGJDOP_03938	7.88e-277	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HDHGJDOP_03939	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HDHGJDOP_03941	9.75e-27	-	-	-	-	-	-	-	-
HDHGJDOP_03943	2.79e-140	-	-	-	-	-	-	-	-
HDHGJDOP_03944	4.23e-103	-	-	-	-	-	-	-	-
HDHGJDOP_03945	2.91e-85	yxiG	-	-	-	-	-	-	-
HDHGJDOP_03946	1.41e-74	yxxG	-	-	-	-	-	-	-
HDHGJDOP_03948	4.8e-251	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HDHGJDOP_03949	7.42e-202	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HDHGJDOP_03950	2.44e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDHGJDOP_03951	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDHGJDOP_03952	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDHGJDOP_03953	1.51e-61	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HDHGJDOP_03954	8.04e-176	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HDHGJDOP_03955	3.55e-204	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HDHGJDOP_03956	0.0	-	-	-	L	-	-	-	Z1 domain
HDHGJDOP_03957	1.12e-99	-	-	-	S	-	-	-	Putative PD-(D/E)XK family member, (DUF4420)
HDHGJDOP_03958	2.49e-244	-	-	-	S	-	-	-	AIPR protein
HDHGJDOP_03959	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HDHGJDOP_03960	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HDHGJDOP_03961	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HDHGJDOP_03962	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HDHGJDOP_03963	7.66e-291	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HDHGJDOP_03964	6.73e-216	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HDHGJDOP_03965	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDHGJDOP_03966	7.43e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HDHGJDOP_03967	2.33e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDHGJDOP_03968	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDHGJDOP_03969	9.22e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDHGJDOP_03970	1.75e-188	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HDHGJDOP_03973	9.45e-26	yxeE	-	-	-	-	-	-	-
HDHGJDOP_03975	9.67e-33	yxeD	-	-	-	-	-	-	-
HDHGJDOP_03976	4.86e-47	-	-	-	-	-	-	-	-
HDHGJDOP_03977	6.74e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HDHGJDOP_03978	2.25e-72	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDHGJDOP_03979	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HDHGJDOP_03980	7.1e-177	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDHGJDOP_03981	9.27e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_03982	6.33e-157	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_03983	1.61e-194	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HDHGJDOP_03984	6.65e-198	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HDHGJDOP_03985	4.92e-209	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HDHGJDOP_03986	2.36e-246	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HDHGJDOP_03987	6.5e-288	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HDHGJDOP_03988	1.73e-218	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HDHGJDOP_03989	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HDHGJDOP_03990	1e-224	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HDHGJDOP_03991	1.11e-196	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HDHGJDOP_03992	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDHGJDOP_03993	1.75e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HDHGJDOP_03994	1.72e-215	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HDHGJDOP_03995	2.13e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDHGJDOP_03996	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HDHGJDOP_03997	1.56e-188	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDHGJDOP_03998	2.06e-129	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDHGJDOP_03999	3.16e-243	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_04000	1.04e-247	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HDHGJDOP_04001	1.53e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDHGJDOP_04002	2.4e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDHGJDOP_04003	2.12e-185	yxaL	-	-	S	-	-	-	PQQ-like domain
HDHGJDOP_04004	5.81e-75	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HDHGJDOP_04005	3.34e-65	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDHGJDOP_04006	1.16e-250	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDHGJDOP_04007	1.49e-85	yxaI	-	-	S	-	-	-	membrane protein domain
HDHGJDOP_04008	3.07e-120	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HDHGJDOP_04009	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HDHGJDOP_04010	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HDHGJDOP_04011	9.59e-234	mrjp	-	-	G	-	-	-	Major royal jelly protein
HDHGJDOP_04012	1.26e-301	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HDHGJDOP_04013	9.17e-200	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HDHGJDOP_04014	2.97e-95	-	-	-	K	-	-	-	Integron-associated effector binding protein
HDHGJDOP_04015	6.31e-98	yjhE	-	-	S	-	-	-	Phage tail protein
HDHGJDOP_04016	0.0	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HDHGJDOP_04017	2.84e-123	tnpR	-	-	L	-	-	-	resolvase
HDHGJDOP_04018	4.04e-103	-	-	-	-	-	-	-	-
HDHGJDOP_04020	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_04021	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDHGJDOP_04022	4.11e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HDHGJDOP_04023	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HDHGJDOP_04024	6.17e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HDHGJDOP_04025	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HDHGJDOP_04026	6.56e-192	-	-	-	S	-	-	-	membrane
HDHGJDOP_04027	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_04028	0.0	-	-	-	I	-	-	-	PLD-like domain
HDHGJDOP_04029	1.16e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDHGJDOP_04030	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HDHGJDOP_04031	1.13e-101	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HDHGJDOP_04032	1.16e-182	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HDHGJDOP_04033	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HDHGJDOP_04034	8.88e-106	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HDHGJDOP_04035	7.21e-200	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HDHGJDOP_04036	3.9e-208	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HDHGJDOP_04037	6.58e-27	-	-	-	-	-	-	-	-
HDHGJDOP_04038	1.74e-53	-	-	-	L	-	-	-	AAA domain
HDHGJDOP_04039	1.63e-281	-	-	-	L	-	-	-	AAA domain
HDHGJDOP_04040	0.0	-	-	-	L	-	-	-	AAA ATPase domain
HDHGJDOP_04041	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDHGJDOP_04045	5.96e-264	yycP	-	-	-	-	-	-	-
HDHGJDOP_04046	1.54e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HDHGJDOP_04047	3.13e-226	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HDHGJDOP_04048	2.13e-106	yycN	-	-	K	-	-	-	Acetyltransferase
HDHGJDOP_04050	2.05e-256	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HDHGJDOP_04051	7.27e-210	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HDHGJDOP_04052	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDHGJDOP_04053	1.75e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HDHGJDOP_04054	1.26e-85	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HDHGJDOP_04055	3.82e-57	sdpR	-	-	K	-	-	-	transcriptional
HDHGJDOP_04056	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HDHGJDOP_04057	8.24e-255	-	-	-	S	-	-	-	Major Facilitator Superfamily
HDHGJDOP_04058	4.44e-309	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HDHGJDOP_04059	3.35e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
HDHGJDOP_04060	6.88e-86	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDHGJDOP_04061	1.37e-270	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDHGJDOP_04062	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HDHGJDOP_04063	6.34e-191	yycI	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_04064	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_04065	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDHGJDOP_04066	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDHGJDOP_04071	4.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDHGJDOP_04072	1.06e-92	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_04073	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDHGJDOP_04074	5.03e-35	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HDHGJDOP_04076	1.21e-23	yycC	-	-	K	-	-	-	YycC-like protein
HDHGJDOP_04077	3.86e-271	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HDHGJDOP_04078	4.55e-243	-	-	-	S	-	-	-	Ecdysteroid kinase
HDHGJDOP_04079	2.87e-291	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HDHGJDOP_04080	3.93e-279	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HDHGJDOP_04081	1.44e-150	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HDHGJDOP_04082	4.29e-103	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HDHGJDOP_04083	2.25e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HDHGJDOP_04084	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HDHGJDOP_04085	8.64e-189	yybS	-	-	S	-	-	-	membrane
HDHGJDOP_04087	3.93e-104	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HDHGJDOP_04088	1.79e-84	yybR	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_04089	4.01e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HDHGJDOP_04090	4.42e-192	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDHGJDOP_04091	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HDHGJDOP_04092	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HDHGJDOP_04093	7.61e-142	-	-	-	K	-	-	-	FCD domain
HDHGJDOP_04094	3.74e-115	-	-	-	S	-	-	-	PFAM DinB family protein
HDHGJDOP_04095	1.96e-184	-	-	-	G	-	-	-	Major Facilitator Superfamily
HDHGJDOP_04096	3.76e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HDHGJDOP_04097	1.56e-144	ydgI	-	-	C	-	-	-	nitroreductase
HDHGJDOP_04098	2.55e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDHGJDOP_04099	7.02e-190	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HDHGJDOP_04100	7.24e-97	yybA	-	-	K	-	-	-	transcriptional
HDHGJDOP_04101	2.85e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDHGJDOP_04102	5e-27	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDHGJDOP_04103	8.63e-130	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HDHGJDOP_04104	3.34e-36	-	-	-	-	-	-	-	-
HDHGJDOP_04105	1.25e-88	ynaF	-	-	-	-	-	-	-
HDHGJDOP_04106	7.1e-207	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HDHGJDOP_04107	7.39e-264	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HDHGJDOP_04108	4.75e-193	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDHGJDOP_04109	2.8e-311	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HDHGJDOP_04110	9.47e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDHGJDOP_04111	1.16e-117	ccpB	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_04112	6.26e-78	ccpB	-	-	K	-	-	-	Transcriptional regulator
HDHGJDOP_04113	2.49e-179	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDHGJDOP_04114	6.58e-112	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDHGJDOP_04115	3.59e-123	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HDHGJDOP_04116	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDHGJDOP_04117	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDHGJDOP_04118	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HDHGJDOP_04119	6.32e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDHGJDOP_04120	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDHGJDOP_04121	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HDHGJDOP_04122	3.84e-215	yyaD	-	-	S	-	-	-	Membrane
HDHGJDOP_04123	2.63e-74	yhhY	-	-	K	-	-	-	FR47-like protein
HDHGJDOP_04124	1.3e-139	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HDHGJDOP_04125	2.76e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDHGJDOP_04126	2.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HDHGJDOP_04127	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HDHGJDOP_04128	2.56e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HDHGJDOP_04129	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDHGJDOP_04130	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDHGJDOP_04131	7.08e-137	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HDHGJDOP_04132	6.08e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDHGJDOP_04133	1.84e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme