ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IMFCMAMH_00001 2.77e-44 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMFCMAMH_00002 2.48e-40 - - - S - - - FRG domain
IMFCMAMH_00003 0.000141 - - - L - - - Recombinase
IMFCMAMH_00004 1.8e-272 - - - V ko:K02557,ko:K09760 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 PFAM secretion protein HlyD family protein
IMFCMAMH_00005 2.89e-11 - - - V ko:K02557,ko:K09760 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 PFAM secretion protein HlyD family protein
IMFCMAMH_00012 1.52e-147 - - - U - - - TraM recognition site of TraD and TraG
IMFCMAMH_00014 4.4e-21 - - - S - - - Ribosomal protein S1-like RNA-binding domain
IMFCMAMH_00016 4.27e-191 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
IMFCMAMH_00017 1.25e-218 - - - KLT - - - serine threonine protein kinase
IMFCMAMH_00018 8.19e-127 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_00020 1.31e-145 - - - NU - - - GBS Bsp-like repeat
IMFCMAMH_00021 1.14e-61 - - - NU - - - GBS Bsp-like repeat
IMFCMAMH_00022 6.09e-40 - - - NU - - - GBS Bsp-like repeat
IMFCMAMH_00023 1.83e-61 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
IMFCMAMH_00024 4.03e-22 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
IMFCMAMH_00027 1.69e-24 - - - D ko:K03496 - ko00000,ko03036,ko04812 Cellulose biosynthesis protein BcsQ
IMFCMAMH_00029 1.68e-93 - - - S - - - Region found in RelA / SpoT proteins
IMFCMAMH_00030 6.21e-18 - - - - - - - -
IMFCMAMH_00032 6.24e-50 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMFCMAMH_00034 2.87e-63 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00036 0.0 - - - L - - - the current gene model (or a revised gene model) may contain a
IMFCMAMH_00038 0.0 salB - - V ko:K20385 ko02024,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
IMFCMAMH_00039 0.0 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMFCMAMH_00040 1.52e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IMFCMAMH_00041 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IMFCMAMH_00042 0.0 - - - T ko:K14988 ko02020,map02020 ko00000,ko00001,ko00002,ko01001,ko02022 Histidine kinase
IMFCMAMH_00043 1.51e-132 salR - - K ko:K14989 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
IMFCMAMH_00044 1.41e-44 - - - L - - - transposase IS116 IS110 IS902 family
IMFCMAMH_00045 2.89e-79 - - - L - - - Transposase IS116 IS110 IS902
IMFCMAMH_00046 7e-197 scnK - - T - - - Histidine kinase
IMFCMAMH_00047 3.08e-122 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_00049 0.0 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
IMFCMAMH_00050 1.03e-288 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 Lantibiotic transport processing ATP-binding protein
IMFCMAMH_00051 2.06e-150 bcrA - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00052 1.92e-106 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00053 7.86e-91 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00054 9.44e-25 - - - L ko:K07497 - ko00000 overlaps another CDS with the same product name
IMFCMAMH_00055 3.86e-113 - - - V - - - Abi-like protein
IMFCMAMH_00056 2.91e-15 - - - K - - - Peptidase S24-like
IMFCMAMH_00057 0.0003 - - - K - - - Helix-turn-helix XRE-family like proteins
IMFCMAMH_00059 6.4e-170 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00060 7.91e-93 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00061 1.31e-210 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase family
IMFCMAMH_00063 1.07e-38 - - - Q - - - ubiE/COQ5 methyltransferase family
IMFCMAMH_00065 0.0 - - - NU - - - GBS Bsp-like repeat
IMFCMAMH_00067 8.43e-262 - - - L - - - Transposase
IMFCMAMH_00068 5e-34 - - - L - - - Transposase
IMFCMAMH_00069 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IMFCMAMH_00070 1.52e-41 - - - L - - - COG3547 Transposase and inactivated derivatives
IMFCMAMH_00071 1.99e-284 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IMFCMAMH_00072 9.69e-170 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
IMFCMAMH_00074 4.08e-47 - - - - - - - -
IMFCMAMH_00078 1.36e-28 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IMFCMAMH_00079 1.16e-91 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IMFCMAMH_00082 6.85e-78 - - - - - - - -
IMFCMAMH_00083 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMFCMAMH_00084 2.83e-172 - - - - - - - -
IMFCMAMH_00085 5.95e-74 - - - - - - - -
IMFCMAMH_00088 4.42e-58 - - - - - - - -
IMFCMAMH_00089 2.3e-235 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IMFCMAMH_00090 1.15e-58 - - - - - - - -
IMFCMAMH_00091 1.63e-117 - - - S - - - Plasmid replication protein
IMFCMAMH_00092 8.29e-27 - - - S - - - MerR HTH family regulatory protein
IMFCMAMH_00093 1.12e-260 - - - L - - - Phage integrase, N-terminal SAM-like domain
IMFCMAMH_00094 2.02e-92 - - - S - - - SIR2-like domain
IMFCMAMH_00095 1.06e-51 - - - L - - - BsuBI PstI restriction endonuclease domain protein
IMFCMAMH_00097 1.31e-41 - - - - - - - -
IMFCMAMH_00099 3.49e-156 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMFCMAMH_00100 1.68e-18 dnaX 2.4.99.16, 2.7.7.7 GH13 D ko:K02343,ko:K02519,ko:K07114,ko:K16147 ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400 cell septum assembly
IMFCMAMH_00102 8.73e-101 topB2 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Bacterial DNA topoisomeraes I ATP-binding domain
IMFCMAMH_00105 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
IMFCMAMH_00106 4.91e-40 - - - - - - - -
IMFCMAMH_00107 1.24e-26 - - - M - - - Putative cell wall binding repeat
IMFCMAMH_00111 5.36e-134 - - - U - - - AAA-like domain
IMFCMAMH_00114 4.59e-93 - - - L - - - Transposase
IMFCMAMH_00115 8.17e-65 - - - L ko:K07497 - ko00000 Integrase core domain protein
IMFCMAMH_00116 5.26e-90 - - - L ko:K07497 - ko00000 Integrase core domain protein
IMFCMAMH_00117 8.86e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
IMFCMAMH_00118 2.05e-163 - - - L ko:K07485 - ko00000 Transposase
IMFCMAMH_00119 3.15e-277 - - - L - - - transposase IS116 IS110 IS902 family
IMFCMAMH_00121 4.61e-27 - - - EF - - - ATP-grasp domain
IMFCMAMH_00124 2.29e-44 - - - EF - - - ATP-grasp domain
IMFCMAMH_00126 5.26e-90 - 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class II (D, K and N)
IMFCMAMH_00127 1.69e-58 - - - Q - - - Methyltransferase domain
IMFCMAMH_00128 2.02e-143 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
IMFCMAMH_00129 1.23e-64 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMFCMAMH_00131 1.83e-53 - - - - - - - -
IMFCMAMH_00133 2.15e-157 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
IMFCMAMH_00138 4.8e-36 - - - - - - - -
IMFCMAMH_00140 1.06e-07 - - - V - - - Psort location Cytoplasmic, score
IMFCMAMH_00141 2.87e-101 - - - P - - - Protein conserved in bacteria
IMFCMAMH_00142 2.07e-101 - - - F - - - Belongs to the Nudix hydrolase family
IMFCMAMH_00143 1.78e-153 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
IMFCMAMH_00144 1.66e-138 - - - K - - - Transcriptional regulator, AbiEi antitoxin
IMFCMAMH_00152 5.22e-39 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IMFCMAMH_00158 2.43e-82 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
IMFCMAMH_00159 0.0 - - - L - - - Transposase
IMFCMAMH_00160 5.22e-174 fasA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
IMFCMAMH_00161 9.38e-312 fasC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_00162 6.42e-258 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_00163 7.66e-196 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_00164 4.12e-293 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 signal transduction protein with a C-terminal ATPase domain
IMFCMAMH_00165 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMFCMAMH_00166 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
IMFCMAMH_00167 1.37e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IMFCMAMH_00168 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMFCMAMH_00169 4.66e-66 - - - S - - - Protein of unknown function (DUF3397)
IMFCMAMH_00170 7.91e-115 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IMFCMAMH_00171 1.02e-163 - - - S - - - Mitochondrial biogenesis AIM24
IMFCMAMH_00172 1.54e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMFCMAMH_00173 1.33e-99 - 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
IMFCMAMH_00174 5.55e-100 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IMFCMAMH_00175 3.33e-140 XK27_09620 - - S - - - FMN reductase (NADPH) activity
IMFCMAMH_00176 7.6e-309 XK27_09615 - - C ko:K19784 - ko00000 reductase
IMFCMAMH_00177 3.14e-183 nirC_1 - - P - - - Formate nitrite transporter
IMFCMAMH_00178 6.03e-128 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
IMFCMAMH_00179 2.08e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IMFCMAMH_00180 9.64e-219 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IMFCMAMH_00181 2.79e-153 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
IMFCMAMH_00182 1.45e-124 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMFCMAMH_00183 2.41e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IMFCMAMH_00184 3.08e-109 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IMFCMAMH_00185 2.71e-182 - - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant
IMFCMAMH_00186 1.47e-205 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
IMFCMAMH_00190 7.78e-114 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IMFCMAMH_00191 4.45e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMFCMAMH_00192 6.94e-150 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IMFCMAMH_00193 4.53e-146 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMFCMAMH_00195 2.86e-72 ytpP - - CO - - - Thioredoxin
IMFCMAMH_00197 8.72e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IMFCMAMH_00198 1.94e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMFCMAMH_00199 1.23e-129 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
IMFCMAMH_00201 7.61e-139 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IMFCMAMH_00202 1.05e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
IMFCMAMH_00203 1.64e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMFCMAMH_00204 2.39e-226 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IMFCMAMH_00205 3.67e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IMFCMAMH_00206 3.23e-93 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
IMFCMAMH_00207 2.48e-21 - - - NU - - - Type II secretory pathway pseudopilin
IMFCMAMH_00208 5.66e-91 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
IMFCMAMH_00209 1.83e-61 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IMFCMAMH_00210 1.09e-184 cglB - - U ko:K02244 - ko00000,ko00002,ko02044 protein transport across the cell outer membrane
IMFCMAMH_00211 5.41e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMFCMAMH_00212 1.37e-91 - - - S - - - cog cog4699
IMFCMAMH_00213 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCMAMH_00214 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCMAMH_00215 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMFCMAMH_00216 1.65e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMFCMAMH_00217 2.99e-247 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMFCMAMH_00218 7.09e-101 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IMFCMAMH_00219 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IMFCMAMH_00220 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IMFCMAMH_00221 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IMFCMAMH_00222 1.87e-76 asp - - S - - - cog cog1302
IMFCMAMH_00223 2e-285 norN - - V - - - Mate efflux family protein
IMFCMAMH_00224 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
IMFCMAMH_00225 7.84e-303 - - - L - - - Transposase
IMFCMAMH_00226 6.82e-05 yebC - - M - - - Membrane
IMFCMAMH_00228 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
IMFCMAMH_00229 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
IMFCMAMH_00230 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IMFCMAMH_00231 0.0 treP 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_00232 1.82e-164 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
IMFCMAMH_00233 2.27e-122 ywlG - - S - - - Belongs to the UPF0340 family
IMFCMAMH_00236 4.88e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_00237 4.93e-211 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
IMFCMAMH_00239 1e-307 - - - H - - - gamma-glutamylcysteine synthetase
IMFCMAMH_00240 3.03e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
IMFCMAMH_00241 2.19e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMFCMAMH_00242 1.63e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMFCMAMH_00243 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMFCMAMH_00244 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IMFCMAMH_00245 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMFCMAMH_00246 9.83e-148 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IMFCMAMH_00247 4.48e-295 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IMFCMAMH_00248 8.47e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IMFCMAMH_00249 9.89e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
IMFCMAMH_00250 7e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMFCMAMH_00251 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMFCMAMH_00252 5.88e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMFCMAMH_00253 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMFCMAMH_00254 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMFCMAMH_00255 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMFCMAMH_00256 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMFCMAMH_00257 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMFCMAMH_00258 1.26e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMFCMAMH_00259 6.2e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IMFCMAMH_00260 4.35e-94 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMFCMAMH_00261 9.44e-153 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMFCMAMH_00262 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMFCMAMH_00263 8.13e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMFCMAMH_00264 5.06e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMFCMAMH_00265 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IMFCMAMH_00266 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IMFCMAMH_00267 3.17e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMFCMAMH_00268 4.29e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IMFCMAMH_00269 2.95e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IMFCMAMH_00270 0.0 XK27_09800 - - I - - - Acyltransferase
IMFCMAMH_00271 4.89e-47 - - - S - - - MORN repeat protein
IMFCMAMH_00272 1.55e-104 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMFCMAMH_00273 3.87e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMFCMAMH_00274 1.04e-119 flaR - - F - - - topology modulation protein
IMFCMAMH_00276 1.46e-220 - - - S - - - membrane
IMFCMAMH_00277 2.74e-117 - - - K - - - Cro/C1-type HTH DNA-binding domain
IMFCMAMH_00278 9.29e-207 - - - L - - - Replication initiation factor
IMFCMAMH_00279 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
IMFCMAMH_00280 7.98e-274 - - - L - - - Belongs to the 'phage' integrase family
IMFCMAMH_00282 9.84e-299 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
IMFCMAMH_00283 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IMFCMAMH_00284 9.75e-59 yrzL - - S - - - Belongs to the UPF0297 family
IMFCMAMH_00285 9.82e-92 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMFCMAMH_00286 1.34e-62 yrzB - - S - - - Belongs to the UPF0473 family
IMFCMAMH_00288 3.33e-304 - - - L - - - Transposase
IMFCMAMH_00289 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00290 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
IMFCMAMH_00291 7.68e-20 - - - - - - - -
IMFCMAMH_00292 7.02e-114 - - - K - - - acetyltransferase
IMFCMAMH_00293 5.13e-149 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMFCMAMH_00294 0.0 - - - L - - - Transposase
IMFCMAMH_00295 1.27e-153 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
IMFCMAMH_00296 2.95e-213 XK27_01785 - - S - - - cog cog1284
IMFCMAMH_00297 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IMFCMAMH_00299 2.17e-304 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IMFCMAMH_00300 9.45e-315 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_00301 8.65e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IMFCMAMH_00302 8.74e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IMFCMAMH_00303 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IMFCMAMH_00304 5.19e-146 - - - L - - - Transposase
IMFCMAMH_00305 4.55e-44 - - - L - - - Transposase
IMFCMAMH_00307 2.01e-151 XK27_06885 - - L - - - hydrolase
IMFCMAMH_00308 4.33e-69 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
IMFCMAMH_00309 3.16e-94 - - - S - - - Protein of unknown function (DUF1700)
IMFCMAMH_00310 5.1e-145 - - - S - - - Putative adhesin
IMFCMAMH_00311 6.44e-258 XK27_06930 - - V ko:K01421 - ko00000 domain protein
IMFCMAMH_00312 1.97e-124 XK27_06935 - - K - - - transcriptional regulator
IMFCMAMH_00313 1.55e-70 XK27_04840 - - M ko:K08987 - ko00000 Membrane
IMFCMAMH_00314 5.32e-13 - - - - - - - -
IMFCMAMH_00315 1.25e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMFCMAMH_00316 6.16e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
IMFCMAMH_00317 1.35e-314 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IMFCMAMH_00318 1.77e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IMFCMAMH_00319 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IMFCMAMH_00320 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IMFCMAMH_00321 6.35e-131 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IMFCMAMH_00322 5.42e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IMFCMAMH_00323 0.0 - - - S - - - Bacterial membrane protein, YfhO
IMFCMAMH_00324 5.86e-127 isaA - - M - - - Immunodominant staphylococcal antigen A
IMFCMAMH_00325 1.15e-101 lytE - - M - - - LysM domain protein
IMFCMAMH_00326 3.07e-170 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCMAMH_00327 1.91e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCMAMH_00328 7.44e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMFCMAMH_00329 2.68e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMFCMAMH_00330 8.21e-167 - - - S ko:K15539 - ko00000 sequence-specific DNA binding
IMFCMAMH_00331 2.01e-304 ymfH - - S - - - Peptidase M16
IMFCMAMH_00332 3.41e-296 albE - - S - - - Peptidase M16
IMFCMAMH_00333 1.77e-76 yaaA - - S - - - S4 domain protein YaaA
IMFCMAMH_00334 1.02e-258 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMFCMAMH_00335 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IMFCMAMH_00336 1.93e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IMFCMAMH_00337 3.8e-193 XK27_10395 - - S - - - membrane
IMFCMAMH_00338 0.0 ykpA - - S - - - abc transporter atp-binding protein
IMFCMAMH_00339 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
IMFCMAMH_00343 7.75e-154 yoaK - - S - - - Protein of unknown function (DUF1275)
IMFCMAMH_00344 8.15e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMFCMAMH_00345 1.01e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IMFCMAMH_00346 5.59e-173 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IMFCMAMH_00347 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00348 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00349 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00350 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
IMFCMAMH_00351 2.91e-200 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMFCMAMH_00352 2.85e-135 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMFCMAMH_00353 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00354 0.0 tcdB - - S ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 dextransucrase activity
IMFCMAMH_00355 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
IMFCMAMH_00356 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00357 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00358 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00359 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_00360 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00362 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_00363 7.14e-145 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
IMFCMAMH_00364 1.21e-58 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IMFCMAMH_00365 5.44e-15 - - - S - - - integral membrane protein
IMFCMAMH_00366 1.8e-246 mccF - - V - - - LD-carboxypeptidase
IMFCMAMH_00367 3.46e-13 - - - S - - - Enterocin A Immunity
IMFCMAMH_00368 6.74e-47 - - - S - - - Immunity protein 41
IMFCMAMH_00369 4.11e-173 - - - T - - - Ser Thr phosphatase family protein
IMFCMAMH_00370 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
IMFCMAMH_00371 5.16e-289 - - - K - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_00372 4.3e-230 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
IMFCMAMH_00373 2.84e-123 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
IMFCMAMH_00374 2.73e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 dihydroxyacetone kinase, phosphotransfer subunit
IMFCMAMH_00375 2.04e-227 XK27_10475 - - S - - - oxidoreductase
IMFCMAMH_00376 7e-250 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 glycerol dehydrogenase
IMFCMAMH_00378 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
IMFCMAMH_00379 4.26e-241 vex1 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
IMFCMAMH_00380 2.49e-140 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00381 9.21e-304 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
IMFCMAMH_00382 1.75e-148 vncR - - K - - - Response regulator receiver domain protein
IMFCMAMH_00383 2.46e-289 vncS 2.7.13.3 - T ko:K10819 - ko00000,ko01000 Histidine kinase
IMFCMAMH_00384 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 COG0366 Glycosidases
IMFCMAMH_00385 1.63e-235 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IMFCMAMH_00386 2.71e-281 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMFCMAMH_00387 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
IMFCMAMH_00388 4.24e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IMFCMAMH_00389 7.38e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
IMFCMAMH_00390 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
IMFCMAMH_00391 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
IMFCMAMH_00392 4.1e-251 - - - S - - - Tetratricopeptide repeat
IMFCMAMH_00393 5.94e-201 yvgN - - C - - - reductase
IMFCMAMH_00394 4.22e-41 XK27_10490 - - - - - - -
IMFCMAMH_00395 3.24e-53 - - - DJ ko:K06218 - ko00000,ko02048 nuclease activity
IMFCMAMH_00396 1.65e-144 - - - S - - - Protein of unknown function (DUF1275)
IMFCMAMH_00397 2.6e-142 yodC - - C - - - nitroreductase
IMFCMAMH_00398 3.01e-154 - - - T - - - Xre family transcriptional regulator
IMFCMAMH_00399 1.17e-176 - - - T - - - His Kinase A (phosphoacceptor) domain
IMFCMAMH_00400 9.56e-57 - - - S - - - Domain of unknown function (DUF4352)
IMFCMAMH_00401 1.41e-164 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00402 2.65e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00403 2.67e-291 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMFCMAMH_00404 5.67e-198 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
IMFCMAMH_00405 1.72e-99 ywnA_2 - - K - - - Transcriptional regulator
IMFCMAMH_00406 2.13e-194 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IMFCMAMH_00407 3.2e-138 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
IMFCMAMH_00408 1.29e-45 - - - - - - - -
IMFCMAMH_00409 1.39e-36 XK27_07105 - - K ko:K07729 - ko00000,ko03000 transcriptional
IMFCMAMH_00411 4.75e-216 ydhF - - S - - - Aldo keto reductase
IMFCMAMH_00412 2.67e-125 - - - K - - - WHG domain
IMFCMAMH_00413 5.24e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00414 1.1e-256 - - - P ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IMFCMAMH_00415 1.39e-56 - - - S - - - Sugar efflux transporter for intercellular exchange
IMFCMAMH_00416 4.62e-107 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IMFCMAMH_00417 5.81e-225 - 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen decarboxylase (URO-D)
IMFCMAMH_00418 1.17e-211 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IMFCMAMH_00419 1.12e-146 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00420 9.58e-147 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
IMFCMAMH_00421 1.88e-175 tcyC2 - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00423 1.03e-61 - - - S - - - dextransucrase activity
IMFCMAMH_00424 0.0 - - - S - - - dextransucrase activity
IMFCMAMH_00425 7.97e-295 yfnA - - E ko:K03294 - ko00000 amino acid
IMFCMAMH_00426 1.2e-66 - - - P - - - Protein conserved in bacteria
IMFCMAMH_00427 4.13e-254 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
IMFCMAMH_00428 1.78e-30 - - - S - - - CsbD-like
IMFCMAMH_00429 1.68e-138 - - - S - - - Protein of unknown function (DUF421)
IMFCMAMH_00430 1.03e-87 - - - S - - - Protein of unknown function (DUF3290)
IMFCMAMH_00431 1.19e-228 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IMFCMAMH_00432 2.22e-296 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IMFCMAMH_00433 6.91e-233 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMFCMAMH_00435 7.57e-303 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IMFCMAMH_00436 4.21e-79 pdxH - - S - - - pyridoxamine 5'-phosphate oxidase
IMFCMAMH_00437 6.95e-283 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
IMFCMAMH_00438 1.25e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IMFCMAMH_00439 3.69e-159 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_00440 3e-207 - - - T - - - Histidine kinase
IMFCMAMH_00441 1.42e-169 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_00442 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IMFCMAMH_00443 1.67e-120 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
IMFCMAMH_00446 9.41e-200 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00447 5.42e-150 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
IMFCMAMH_00448 4.74e-106 - - - F - - - cytidine deaminase activity
IMFCMAMH_00449 1.19e-209 yocS - - S ko:K03453 - ko00000 Transporter
IMFCMAMH_00452 1.9e-151 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00453 1.49e-26 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00454 1.01e-170 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IMFCMAMH_00455 2.31e-238 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMFCMAMH_00456 8.09e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMFCMAMH_00457 3.18e-237 - - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00458 5.16e-182 M1-956 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00459 9e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00460 9.83e-101 - - - K - - - Acetyltransferase (GNAT) domain
IMFCMAMH_00461 0.0 prtA - - O - - - Belongs to the peptidase S8 family
IMFCMAMH_00462 1.61e-64 ywrO - - S ko:K11748 - ko00000,ko02000 general stress protein
IMFCMAMH_00463 1.72e-193 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_00464 2.43e-136 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00465 8.1e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_00466 2.61e-208 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_00467 8.06e-104 - - - S - - - RDD family
IMFCMAMH_00468 1.01e-184 yjlA - - EG - - - membrane
IMFCMAMH_00469 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IMFCMAMH_00470 4.58e-189 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IMFCMAMH_00471 4.47e-154 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IMFCMAMH_00472 3.26e-160 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
IMFCMAMH_00473 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IMFCMAMH_00474 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMFCMAMH_00475 2.95e-117 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
IMFCMAMH_00476 0.0 clsA_1 - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMFCMAMH_00477 8.77e-158 alkD - - L - - - Dna alkylation repair
IMFCMAMH_00478 1.44e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMFCMAMH_00479 3.65e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMFCMAMH_00480 1.52e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IMFCMAMH_00481 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IMFCMAMH_00482 5.59e-116 - - - S - - - Protein of unknown function (DUF3278)
IMFCMAMH_00483 7.46e-32 WQ51_00220 - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
IMFCMAMH_00484 2.78e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMFCMAMH_00485 2.16e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMFCMAMH_00486 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IMFCMAMH_00488 6.52e-75 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
IMFCMAMH_00489 0.0 - - - L - - - Transposase
IMFCMAMH_00490 4.04e-302 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IMFCMAMH_00492 1.99e-110 - - - S - - - ECF-type riboflavin transporter, S component
IMFCMAMH_00493 1.14e-196 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
IMFCMAMH_00494 3.95e-109 - - - S - - - ECF-type riboflavin transporter, S component
IMFCMAMH_00495 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
IMFCMAMH_00496 0.0 noxE - - P - - - NADH oxidase
IMFCMAMH_00497 7.17e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IMFCMAMH_00498 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMFCMAMH_00499 3.78e-170 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
IMFCMAMH_00500 1.76e-92 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IMFCMAMH_00501 5.67e-211 ypuA - - S - - - secreted protein
IMFCMAMH_00502 1.28e-293 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
IMFCMAMH_00503 3.52e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
IMFCMAMH_00504 2.58e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IMFCMAMH_00505 7.12e-226 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
IMFCMAMH_00506 1.46e-192 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
IMFCMAMH_00507 3.42e-235 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMFCMAMH_00508 4.74e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IMFCMAMH_00509 7.92e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMFCMAMH_00510 3.56e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IMFCMAMH_00511 1.41e-139 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IMFCMAMH_00512 1.06e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMFCMAMH_00513 7.41e-229 - - - S - - - 37-kD nucleoid-associated bacterial protein
IMFCMAMH_00514 2.93e-126 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
IMFCMAMH_00515 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00516 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00517 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMFCMAMH_00518 3.43e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
IMFCMAMH_00519 7.07e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IMFCMAMH_00520 2.46e-308 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IMFCMAMH_00521 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
IMFCMAMH_00522 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
IMFCMAMH_00524 3e-221 - - - L ko:K07482 - ko00000 Integrase
IMFCMAMH_00525 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMFCMAMH_00526 9.54e-208 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
IMFCMAMH_00527 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IMFCMAMH_00528 1.45e-118 - - - S - - - ECF transporter, substrate-specific component
IMFCMAMH_00529 2.47e-119 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMFCMAMH_00530 5e-84 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
IMFCMAMH_00531 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
IMFCMAMH_00532 2.39e-154 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_00533 5.01e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMFCMAMH_00534 4.36e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IMFCMAMH_00535 1.09e-219 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IMFCMAMH_00536 7.26e-133 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
IMFCMAMH_00537 1.39e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IMFCMAMH_00538 1.74e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMFCMAMH_00539 3.93e-90 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IMFCMAMH_00540 1.04e-246 - - - S ko:K07335 - ko00000 membrane
IMFCMAMH_00541 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_00542 9.03e-236 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMFCMAMH_00543 8.2e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMFCMAMH_00544 5.09e-154 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IMFCMAMH_00545 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IMFCMAMH_00546 6.3e-105 ypmB - - S - - - Protein conserved in bacteria
IMFCMAMH_00547 2.78e-272 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IMFCMAMH_00548 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IMFCMAMH_00550 2.15e-82 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
IMFCMAMH_00551 4.52e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IMFCMAMH_00552 5.15e-109 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IMFCMAMH_00553 3.04e-173 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IMFCMAMH_00554 6.8e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IMFCMAMH_00555 2.71e-301 - - - D - - - nuclear chromosome segregation
IMFCMAMH_00556 2.2e-175 yejC - - S - - - cyclic nucleotide-binding protein
IMFCMAMH_00557 3.6e-210 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IMFCMAMH_00558 1.06e-232 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IMFCMAMH_00559 1.99e-206 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IMFCMAMH_00560 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IMFCMAMH_00561 7.71e-189 XK27_10720 - - D - - - peptidase activity
IMFCMAMH_00562 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IMFCMAMH_00565 3.33e-221 yeiH - - S - - - Membrane
IMFCMAMH_00566 7.44e-169 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
IMFCMAMH_00567 8.86e-214 cpsY - - K - - - Transcriptional regulator
IMFCMAMH_00568 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IMFCMAMH_00569 7.1e-78 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
IMFCMAMH_00570 1.17e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00571 7.5e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00572 1.07e-200 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IMFCMAMH_00573 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMFCMAMH_00574 3.4e-65 - - - - - - - -
IMFCMAMH_00575 1.7e-59 - - - - - - - -
IMFCMAMH_00576 9.5e-239 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IMFCMAMH_00577 5.34e-134 - - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMFCMAMH_00578 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IMFCMAMH_00579 3.02e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
IMFCMAMH_00580 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMFCMAMH_00581 5.49e-314 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMFCMAMH_00582 1.64e-19 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMFCMAMH_00583 1.33e-111 - - - - ko:K16788 - ko00000,ko02000 -
IMFCMAMH_00584 6.7e-119 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IMFCMAMH_00585 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
IMFCMAMH_00586 1.15e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMFCMAMH_00587 1.04e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMFCMAMH_00588 4.33e-207 - - - GK - - - ROK family
IMFCMAMH_00589 5.28e-199 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
IMFCMAMH_00590 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMFCMAMH_00591 2.09e-106 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IMFCMAMH_00592 1.88e-68 - - - V ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IMFCMAMH_00594 1.34e-194 - - - S - - - TraX protein
IMFCMAMH_00595 7.75e-153 yycF1 - - T ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_00596 5.75e-303 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
IMFCMAMH_00597 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMFCMAMH_00598 8.11e-287 XK27_05470 - - E - - - Methionine synthase
IMFCMAMH_00599 2.06e-66 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IMFCMAMH_00600 0.0 - - - V ko:K13732 ko05100,map05100 ko00000,ko00001 Glucan-binding protein C
IMFCMAMH_00601 5.87e-156 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMFCMAMH_00602 4.3e-297 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMFCMAMH_00603 2.69e-123 - - - S - - - Protein of unknown function (DUF1697)
IMFCMAMH_00604 2.92e-191 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMFCMAMH_00605 8.32e-229 - - - P - - - Chloride transporter, ClC family
IMFCMAMH_00606 4.16e-175 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
IMFCMAMH_00607 6.61e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
IMFCMAMH_00608 2.48e-25 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00610 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IMFCMAMH_00613 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IMFCMAMH_00614 1.9e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
IMFCMAMH_00615 1.26e-53 - - - C - - - Pyridoxamine 5'-phosphate oxidase
IMFCMAMH_00616 1.74e-106 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IMFCMAMH_00617 1.57e-40 - - - S - - - Macro domain protein
IMFCMAMH_00618 8.1e-89 - - - K - - - Transcriptional regulator, MarR family
IMFCMAMH_00619 4.04e-170 - - - GM - - - NmrA-like family
IMFCMAMH_00620 1.2e-213 - - - C - - - alcohol dehydrogenase
IMFCMAMH_00621 1.01e-164 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00622 0.0 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMFCMAMH_00623 1.83e-138 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
IMFCMAMH_00624 1.55e-180 - - - S - - - Phenazine biosynthesis protein
IMFCMAMH_00625 8.69e-127 - 2.7.7.65 - T ko:K16923,ko:K18967 - ko00000,ko00002,ko01000,ko02000 phosphorelay sensor kinase activity
IMFCMAMH_00626 3.45e-169 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IMFCMAMH_00627 1.03e-200 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00628 3.84e-190 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'abc transporter, ATP-binding protein
IMFCMAMH_00629 3.57e-146 - - - L ko:K07498 - ko00000 DDE domain
IMFCMAMH_00630 6.55e-95 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
IMFCMAMH_00631 1.75e-10 - - - - - - - -
IMFCMAMH_00632 1.9e-79 - - - S - - - Protein of unknown function with HXXEE motif
IMFCMAMH_00633 1.28e-125 - - - K - - - Transcriptional regulator, TetR family
IMFCMAMH_00634 3.87e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
IMFCMAMH_00635 1.42e-248 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IMFCMAMH_00636 1.45e-236 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
IMFCMAMH_00637 8.03e-194 - - - L - - - PFAM Integrase catalytic region
IMFCMAMH_00638 1.22e-86 copY - - K - - - Copper transport repressor, CopY TcrY family
IMFCMAMH_00639 3.75e-86 - - - S - - - cog cog4633
IMFCMAMH_00640 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IMFCMAMH_00641 3.68e-16 spxB 1.2.3.3 - C ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
IMFCMAMH_00642 4.88e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_00643 1.39e-189 - - - G - - - protein with an alpha beta hydrolase fold
IMFCMAMH_00644 1.49e-164 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00645 3.81e-235 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IMFCMAMH_00646 1.68e-137 - - - K - - - Bacterial regulatory proteins, tetR family
IMFCMAMH_00647 7.05e-171 - - - F - - - Phosphorylase superfamily
IMFCMAMH_00648 6.61e-141 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
IMFCMAMH_00649 0.0 - - - V - - - Type III restriction enzyme, res subunit
IMFCMAMH_00650 1.68e-228 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
IMFCMAMH_00651 4.31e-296 dinF - - V - - - Mate efflux family protein
IMFCMAMH_00652 6.39e-191 - - - S - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_00653 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IMFCMAMH_00654 1.96e-183 - - - S - - - TraX protein
IMFCMAMH_00655 3.79e-119 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
IMFCMAMH_00656 1.49e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IMFCMAMH_00657 3.95e-225 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IMFCMAMH_00658 5.04e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IMFCMAMH_00659 3.05e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMFCMAMH_00660 5.25e-302 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
IMFCMAMH_00661 2.29e-190 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IMFCMAMH_00662 1.33e-104 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00663 0.0 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMFCMAMH_00664 5.24e-48 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMFCMAMH_00665 1.25e-208 bglC - - K - - - Transcriptional regulator
IMFCMAMH_00666 4.19e-315 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMFCMAMH_00667 7.39e-309 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
IMFCMAMH_00668 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IMFCMAMH_00669 1.4e-305 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
IMFCMAMH_00670 5.71e-91 - - - S - - - haloacid dehalogenase-like hydrolase
IMFCMAMH_00671 1.66e-111 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMFCMAMH_00672 4.7e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
IMFCMAMH_00673 1.76e-47 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
IMFCMAMH_00674 0.0 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
IMFCMAMH_00675 1.5e-188 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMFCMAMH_00676 5.78e-215 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IMFCMAMH_00677 3.58e-93 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IMFCMAMH_00678 4.17e-60 yktA - - S - - - Belongs to the UPF0223 family
IMFCMAMH_00679 3.26e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
IMFCMAMH_00680 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
IMFCMAMH_00681 2.31e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
IMFCMAMH_00682 1.33e-200 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IMFCMAMH_00683 5.16e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
IMFCMAMH_00684 7.48e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMFCMAMH_00685 2.49e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IMFCMAMH_00686 1.33e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
IMFCMAMH_00687 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
IMFCMAMH_00688 5.32e-248 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IMFCMAMH_00689 3.58e-238 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IMFCMAMH_00692 4.88e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_00693 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IMFCMAMH_00694 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
IMFCMAMH_00695 8.48e-221 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IMFCMAMH_00696 3.38e-291 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMFCMAMH_00697 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00698 2.6e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00699 1.37e-269 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMFCMAMH_00700 9.68e-34 - - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IMFCMAMH_00701 5.04e-154 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMFCMAMH_00702 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
IMFCMAMH_00703 2.38e-293 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
IMFCMAMH_00704 7.66e-193 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
IMFCMAMH_00705 3.11e-231 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
IMFCMAMH_00706 5e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00707 2.69e-199 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCMAMH_00708 2.71e-195 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCMAMH_00709 0.0 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
IMFCMAMH_00710 5.69e-111 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
IMFCMAMH_00711 0.0 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
IMFCMAMH_00712 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
IMFCMAMH_00713 7.31e-282 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMFCMAMH_00714 2.3e-231 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IMFCMAMH_00715 4.34e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
IMFCMAMH_00716 2.55e-275 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_00717 5.09e-300 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_00718 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00719 3.58e-301 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IMFCMAMH_00720 7.76e-152 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMFCMAMH_00721 9.41e-278 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMFCMAMH_00722 0.0 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
IMFCMAMH_00723 3.49e-230 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
IMFCMAMH_00724 1.64e-204 - - - S - - - Phospholipase, patatin family
IMFCMAMH_00725 1.01e-135 - - - E - - - Lysophospholipase L1 and related esterases
IMFCMAMH_00726 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
IMFCMAMH_00727 2.35e-52 - - - S - - - granule-associated protein
IMFCMAMH_00728 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMFCMAMH_00729 1.87e-251 XK27_12525 - - S - - - hmm pf01594
IMFCMAMH_00730 6.61e-140 - - - G - - - Belongs to the phosphoglycerate mutase family
IMFCMAMH_00731 1.77e-136 - - - G - - - Belongs to the phosphoglycerate mutase family
IMFCMAMH_00732 3.39e-141 XK27_06100 - - G - - - Belongs to the phosphoglycerate mutase family
IMFCMAMH_00733 4.3e-190 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
IMFCMAMH_00734 9.6e-307 - - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
IMFCMAMH_00735 0.0 - - - M - - - Polysaccharide biosynthesis protein
IMFCMAMH_00736 2.72e-261 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMFCMAMH_00737 8.26e-219 galnac-T15 - - S ko:K07011 - ko00000 glycosyl transferase family 2
IMFCMAMH_00738 4.69e-104 - - - - - - - -
IMFCMAMH_00739 1.07e-261 - - - M - - - glycosyl transferase group 1
IMFCMAMH_00740 1.47e-210 - - - S - - - Glycosyl transferase family 2
IMFCMAMH_00741 4.56e-206 licD - - M ko:K07271 - ko00000,ko01000 LICD family
IMFCMAMH_00742 2.56e-163 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IMFCMAMH_00743 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IMFCMAMH_00744 1.34e-156 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
IMFCMAMH_00745 2.45e-150 capA - - M - - - biosynthesis protein
IMFCMAMH_00746 1.05e-171 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
IMFCMAMH_00747 5.95e-305 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IMFCMAMH_00748 2.28e-144 ung2 - - L - - - Uracil-DNA glycosylase
IMFCMAMH_00749 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
IMFCMAMH_00750 1.38e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
IMFCMAMH_00751 2.72e-119 yybC - - - - - - -
IMFCMAMH_00752 5.14e-108 XK27_03610 - - K - - - Gnat family
IMFCMAMH_00753 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMFCMAMH_00754 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IMFCMAMH_00755 3.15e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMFCMAMH_00756 3.39e-155 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IMFCMAMH_00757 6.59e-27 XK27_09115 - - M - - - LysM domain
IMFCMAMH_00758 4.23e-115 ebsA - - S - - - Family of unknown function (DUF5322)
IMFCMAMH_00759 8.35e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IMFCMAMH_00760 0.0 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
IMFCMAMH_00761 3.79e-125 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IMFCMAMH_00762 2.75e-287 XK27_05225 - - G - - - COG0457 FOG TPR repeat
IMFCMAMH_00763 3.84e-235 XK27_05220 - - S - - - permease
IMFCMAMH_00764 5.85e-119 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IMFCMAMH_00765 8.45e-211 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IMFCMAMH_00766 8.67e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IMFCMAMH_00767 1.08e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMFCMAMH_00768 2.86e-268 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMFCMAMH_00769 4.14e-202 - - - S - - - Calcineurin-like phosphoesterase
IMFCMAMH_00770 1.05e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
IMFCMAMH_00771 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
IMFCMAMH_00772 2.05e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
IMFCMAMH_00773 1.01e-140 - - - F - - - Phosphorylase superfamily
IMFCMAMH_00774 7.25e-206 XK27_00115 - - K - - - Acetyltransferase GNAT family
IMFCMAMH_00775 3.03e-188 XK27_00835 - - S - - - hydrolases of the HAD superfamily
IMFCMAMH_00776 5.85e-275 murM 2.3.2.10 - V ko:K05363 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
IMFCMAMH_00777 2.21e-74 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
IMFCMAMH_00778 8.43e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
IMFCMAMH_00779 5.5e-315 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMFCMAMH_00780 1.44e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_00781 1.1e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00782 9e-190 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IMFCMAMH_00783 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00784 1.75e-143 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IMFCMAMH_00785 1.05e-177 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_00786 2.76e-184 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IMFCMAMH_00787 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_00788 1.01e-142 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IMFCMAMH_00789 1.56e-198 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
IMFCMAMH_00790 2.03e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
IMFCMAMH_00791 3.97e-294 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMFCMAMH_00792 3.91e-248 - - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IMFCMAMH_00793 1.45e-314 ydaM - - M - - - Glycosyltransferases, probably involved in cell wall biogenesis
IMFCMAMH_00795 2.62e-168 - - - - - - - -
IMFCMAMH_00796 1.14e-275 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IMFCMAMH_00797 2.1e-269 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMFCMAMH_00798 1.54e-219 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IMFCMAMH_00799 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMFCMAMH_00800 4.9e-111 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IMFCMAMH_00801 1.34e-204 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMFCMAMH_00802 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
IMFCMAMH_00805 2.33e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IMFCMAMH_00806 5.29e-266 eriC - - P ko:K03281 - ko00000 Chloride transporter ClC family
IMFCMAMH_00807 1.74e-53 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
IMFCMAMH_00808 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
IMFCMAMH_00809 3.48e-98 ykuP - - C ko:K03839 - ko00000 Flavodoxin
IMFCMAMH_00810 5.06e-26 XK27_08880 - - - - - - -
IMFCMAMH_00811 3.8e-163 XK27_08875 - - O - - - Zinc-dependent metalloprotease
IMFCMAMH_00812 2.41e-190 estA - CE1 S ko:K03930 - ko00000,ko01000 Esterase
IMFCMAMH_00813 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMFCMAMH_00814 5.4e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_00815 1.37e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMFCMAMH_00816 2.78e-228 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
IMFCMAMH_00818 4.06e-40 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
IMFCMAMH_00819 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IMFCMAMH_00820 2.72e-238 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IMFCMAMH_00821 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IMFCMAMH_00822 5.58e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMFCMAMH_00823 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMFCMAMH_00824 1.41e-49 ysdA - - L - - - Membrane
IMFCMAMH_00825 1.36e-241 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IMFCMAMH_00826 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMFCMAMH_00827 1.24e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMFCMAMH_00828 1.44e-228 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
IMFCMAMH_00830 3.1e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IMFCMAMH_00831 5.77e-127 ypmS - - S - - - Protein conserved in bacteria
IMFCMAMH_00832 4.73e-208 XK27_03630 - - E - - - COG2755 Lysophospholipase L1 and related esterases
IMFCMAMH_00833 1.18e-191 WQ51_01275 - - S - - - DegV family
IMFCMAMH_00834 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IMFCMAMH_00835 5.12e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IMFCMAMH_00836 2.58e-188 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
IMFCMAMH_00837 1.44e-197 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IMFCMAMH_00838 3.47e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMFCMAMH_00839 2.66e-298 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IMFCMAMH_00841 1.84e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMFCMAMH_00842 3.15e-163 dnaD - - - ko:K02086 - ko00000 -
IMFCMAMH_00843 6.91e-233 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMFCMAMH_00844 7.52e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMFCMAMH_00845 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
IMFCMAMH_00846 3.61e-87 GnaT 2.5.1.16 - K ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferase
IMFCMAMH_00847 4.28e-177 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IMFCMAMH_00848 1.81e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IMFCMAMH_00849 3.55e-146 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
IMFCMAMH_00850 1.11e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMFCMAMH_00851 4.47e-299 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IMFCMAMH_00852 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_00853 1.36e-303 - - - L - - - Transposase
IMFCMAMH_00854 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_00855 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_00856 4.79e-228 - - - M - - - glycosyl transferase family 2
IMFCMAMH_00857 3.4e-164 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
IMFCMAMH_00858 2.31e-183 - - - P - - - molecular chaperone
IMFCMAMH_00859 4.61e-133 XK27_05505 - - S - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_00862 1.27e-66 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
IMFCMAMH_00863 6.01e-80 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMFCMAMH_00864 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IMFCMAMH_00865 4.13e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMFCMAMH_00866 1.16e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMFCMAMH_00867 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IMFCMAMH_00868 4.35e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMFCMAMH_00869 2.93e-151 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IMFCMAMH_00870 1.89e-227 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMFCMAMH_00871 2.12e-252 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMFCMAMH_00872 9.02e-77 XK27_08085 - - - - - - -
IMFCMAMH_00873 4.59e-198 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
IMFCMAMH_00874 4.31e-177 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
IMFCMAMH_00875 5.5e-155 - - - S - - - tigr01906
IMFCMAMH_00876 1.1e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IMFCMAMH_00877 2.61e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
IMFCMAMH_00878 4.45e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IMFCMAMH_00881 3.86e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IMFCMAMH_00882 5.56e-142 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IMFCMAMH_00883 7.83e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMFCMAMH_00884 0.0 - - - S - - - phospholipase Carboxylesterase
IMFCMAMH_00885 1.38e-254 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
IMFCMAMH_00886 6.54e-187 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
IMFCMAMH_00887 1.06e-185 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMFCMAMH_00888 9.32e-154 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IMFCMAMH_00889 2.05e-83 mesH - - S - - - GtrA-like protein
IMFCMAMH_00890 9.24e-317 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMFCMAMH_00891 5.12e-218 ybbR - - S - - - Protein conserved in bacteria
IMFCMAMH_00892 2.27e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMFCMAMH_00893 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
IMFCMAMH_00894 3.57e-193 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
IMFCMAMH_00895 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMFCMAMH_00896 9.04e-171 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
IMFCMAMH_00897 7.55e-53 - - - S - - - yiaA/B two helix domain
IMFCMAMH_00898 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
IMFCMAMH_00899 5.27e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IMFCMAMH_00900 6.43e-227 yfmL - - L - - - DEAD DEAH box helicase
IMFCMAMH_00901 1.16e-286 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
IMFCMAMH_00902 4.54e-197 XK27_05675 - - S - - - Esterase
IMFCMAMH_00903 1.07e-205 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
IMFCMAMH_00904 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IMFCMAMH_00905 9.41e-279 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_00906 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMFCMAMH_00907 2.72e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
IMFCMAMH_00908 3.29e-279 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
IMFCMAMH_00909 4.75e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IMFCMAMH_00910 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMFCMAMH_00911 1.37e-45 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
IMFCMAMH_00912 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMFCMAMH_00913 1.84e-235 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMFCMAMH_00914 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMFCMAMH_00915 2.89e-193 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IMFCMAMH_00916 4.46e-185 ylmH - - S - - - conserved protein, contains S4-like domain
IMFCMAMH_00917 9.29e-40 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
IMFCMAMH_00918 1.21e-130 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
IMFCMAMH_00919 9.77e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMFCMAMH_00920 1.31e-303 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMFCMAMH_00921 1.23e-308 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IMFCMAMH_00922 3.65e-186 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IMFCMAMH_00923 2.49e-254 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMFCMAMH_00924 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMFCMAMH_00925 4.2e-11 - - - S - - - Protein of unknown function (DUF3165)
IMFCMAMH_00926 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IMFCMAMH_00927 4.82e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IMFCMAMH_00928 1.86e-37 yqgQ - - S - - - protein conserved in bacteria
IMFCMAMH_00929 9.25e-108 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IMFCMAMH_00930 1.35e-119 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IMFCMAMH_00931 1.34e-147 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IMFCMAMH_00932 1.22e-238 - - - V - - - D-alanyl-D-alanine carboxypeptidase
IMFCMAMH_00933 1.59e-143 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IMFCMAMH_00934 5.47e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IMFCMAMH_00935 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IMFCMAMH_00936 6.55e-84 - - - S - - - Domain of unknown function (DUF4430)
IMFCMAMH_00937 9.64e-94 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
IMFCMAMH_00938 2.47e-165 sitB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_00939 4.06e-171 mtsC - - P ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type Mn2 Zn2 transport systems, permease components
IMFCMAMH_00940 6.27e-214 psaA - - P ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IMFCMAMH_00941 1.4e-153 sirR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
IMFCMAMH_00942 3.45e-189 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IMFCMAMH_00943 1.08e-120 lemA - - S ko:K03744 - ko00000 LemA family
IMFCMAMH_00944 6.45e-241 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
IMFCMAMH_00945 0.0 - - - M - - - Right handed beta helix region
IMFCMAMH_00946 1.1e-34 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
IMFCMAMH_00947 8.66e-180 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
IMFCMAMH_00948 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
IMFCMAMH_00949 4.42e-57 - - - K - - - Helix-turn-helix domain
IMFCMAMH_00950 2.71e-66 - - - S - - - Protein conserved in bacteria
IMFCMAMH_00951 0.0 - - - S - - - KAP family P-loop domain
IMFCMAMH_00952 9.06e-127 - - - V - - - Type I restriction modification DNA specificity domain
IMFCMAMH_00953 3.78e-305 - - - L - - - Psort location Cytoplasmic, score 8.87
IMFCMAMH_00954 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
IMFCMAMH_00955 4.88e-60 - - - K - - - Helix-turn-helix domain
IMFCMAMH_00956 4.74e-61 - - - S - - - Phage derived protein Gp49-like (DUF891)
IMFCMAMH_00957 1.73e-171 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IMFCMAMH_00958 2.74e-266 - - - S - - - Protein of unknown function (DUF2974)
IMFCMAMH_00959 3.58e-148 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMFCMAMH_00960 1.59e-205 hmpP2 - - G - - - hydrolase
IMFCMAMH_00961 3.49e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
IMFCMAMH_00962 1.15e-194 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
IMFCMAMH_00963 7.84e-303 - - - L - - - Transposase
IMFCMAMH_00964 2.13e-106 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMFCMAMH_00965 4.34e-151 pgm - - G - - - Phosphoglycerate mutase
IMFCMAMH_00966 3.26e-224 - - - S ko:K07025 - ko00000 hydrolase
IMFCMAMH_00967 1.22e-36 - - - - - - - -
IMFCMAMH_00968 2.6e-236 - - - M - - - LysM domain
IMFCMAMH_00969 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IMFCMAMH_00971 3.98e-296 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IMFCMAMH_00972 6e-45 XK27_12190 - - S - - - protein conserved in bacteria
IMFCMAMH_00974 2.45e-109 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
IMFCMAMH_00975 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IMFCMAMH_00976 1.75e-228 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IMFCMAMH_00978 3.91e-90 ytxH - - S - - - General stress protein
IMFCMAMH_00979 9.98e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMFCMAMH_00980 2.72e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMFCMAMH_00981 6.94e-210 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMFCMAMH_00982 1.45e-55 WQ51_05770 - - KT - - - PspC domain
IMFCMAMH_00983 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
IMFCMAMH_00985 3.26e-199 XK27_03015 - - S ko:K07089 - ko00000 permease
IMFCMAMH_00986 2.4e-191 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
IMFCMAMH_00987 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 Sulfate permease and related transporters (MFS superfamily)
IMFCMAMH_00988 1.23e-128 - - - - - - - -
IMFCMAMH_00989 6.88e-144 - - - E - - - GDSL-like Lipase/Acylhydrolase
IMFCMAMH_00990 2.25e-119 - - - S - - - CAAX protease self-immunity
IMFCMAMH_00991 3.19e-69 - - - - - - - -
IMFCMAMH_00994 6.81e-83 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
IMFCMAMH_00995 7.98e-80 - - - S - - - Protein of unknown function (DUF1722)
IMFCMAMH_00996 4.1e-28 - - - M - - - Bacterial lipoprotein
IMFCMAMH_00998 1.81e-164 - - - V - - - CAAX protease self-immunity
IMFCMAMH_00999 8.63e-60 - - - - - - - -
IMFCMAMH_01000 3.33e-96 - - - K - - - TetR family transcriptional regulator
IMFCMAMH_01001 7.69e-103 - - - Q - - - Methyltransferase domain
IMFCMAMH_01002 4.02e-181 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IMFCMAMH_01003 2.63e-222 acoB - - C ko:K21417 - ko00000,ko01000 dehydrogenase E1 component
IMFCMAMH_01004 1.65e-146 acoA - - C ko:K21416 - ko00000,ko01000 Acetoin dehydrogenase E1 component subunit alpha
IMFCMAMH_01005 1.63e-52 acoA - - C ko:K21416 - ko00000,ko01000 Acetoin dehydrogenase E1 component subunit alpha
IMFCMAMH_01006 6.02e-217 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
IMFCMAMH_01007 6.53e-32 - - - K - - - CsbD-like
IMFCMAMH_01008 6.06e-28 - - - S - - - CsbD-like
IMFCMAMH_01009 1.08e-93 - - - S - - - Asp23 family, cell envelope-related function
IMFCMAMH_01010 2.97e-30 - - - S - - - Small integral membrane protein
IMFCMAMH_01011 4e-125 - - - - - - - -
IMFCMAMH_01012 6.33e-42 ytgB - - S - - - Membrane
IMFCMAMH_01014 4.98e-219 - - - S - - - Domain of unknown function (DUF389)
IMFCMAMH_01015 1.05e-196 yegS - - I - - - Diacylglycerol kinase
IMFCMAMH_01016 1.54e-158 - - - S - - - Putative esterase
IMFCMAMH_01017 8.28e-228 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IMFCMAMH_01018 1.23e-174 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IMFCMAMH_01019 1.7e-209 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMFCMAMH_01020 2.72e-159 - - - V - - - CAAX protease self-immunity
IMFCMAMH_01021 2.93e-196 - - - S - - - Domain of unknown function (DUF4300)
IMFCMAMH_01022 0.0 - - - M - - - family 8
IMFCMAMH_01023 6.34e-139 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
IMFCMAMH_01024 2.08e-166 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
IMFCMAMH_01025 6.51e-126 yagB - - F ko:K06950 - ko00000 HD superfamily hydrolase
IMFCMAMH_01026 2.83e-125 - - - K - - - Bacterial regulatory proteins, tetR family
IMFCMAMH_01027 1.01e-192 ChZ00x2 - - S - - - EDD domain protein, DegV family
IMFCMAMH_01028 2.8e-259 yycB - - P ko:K03449 - ko00000,ko02000 transporter
IMFCMAMH_01029 1.8e-95 - - - J - - - Acetyltransferase GNAT family
IMFCMAMH_01030 5.43e-181 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCMAMH_01032 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IMFCMAMH_01033 4.62e-81 - - - K ko:K21903 - ko00000,ko03000 Transcriptional regulator
IMFCMAMH_01034 2.08e-68 XK27_05385 - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
IMFCMAMH_01035 6.36e-98 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
IMFCMAMH_01036 2.29e-180 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCMAMH_01037 4.9e-75 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
IMFCMAMH_01038 2.27e-59 - - - - - - - -
IMFCMAMH_01039 8.23e-126 - - - - - - - -
IMFCMAMH_01040 5.07e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IMFCMAMH_01041 2.03e-165 lyrA - - S - - - CAAX amino terminal protease family protein
IMFCMAMH_01042 1.17e-73 - - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IMFCMAMH_01043 3.67e-45 - - - S - - - Protein of unknown function (DUF1648)
IMFCMAMH_01044 0.0 - - - S ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
IMFCMAMH_01045 5.66e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IMFCMAMH_01046 2.82e-139 - - - K - - - Transcriptional regulator
IMFCMAMH_01047 1.66e-125 - - - - - - - -
IMFCMAMH_01048 1.9e-84 - - - K - - - Acetyltransferase (GNAT) domain
IMFCMAMH_01049 2.41e-25 - - - S ko:K06889 - ko00000 alpha beta
IMFCMAMH_01050 1.3e-69 - - - K - - - TfoX N-terminal domain
IMFCMAMH_01051 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMFCMAMH_01052 1.28e-126 mip - - S - - - hydroperoxide reductase activity
IMFCMAMH_01053 8.66e-254 - - - I - - - acyl-CoA dehydrogenase
IMFCMAMH_01054 3.2e-196 ydiA - - P ko:K03304,ko:K11041 ko05150,map05150 ko00000,ko00001,ko02000,ko02042 C4-dicarboxylate transporter malic acid transport protein
IMFCMAMH_01055 0.0 msrR - - K - - - Transcriptional regulator
IMFCMAMH_01056 2.82e-196 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IMFCMAMH_01057 1.08e-111 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMFCMAMH_01058 9.39e-295 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IMFCMAMH_01059 6.02e-219 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
IMFCMAMH_01060 2.99e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
IMFCMAMH_01061 7.51e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IMFCMAMH_01062 2.53e-75 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMFCMAMH_01063 2.75e-146 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMFCMAMH_01064 5.89e-257 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMFCMAMH_01065 4.86e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMFCMAMH_01066 4.8e-150 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IMFCMAMH_01067 6.89e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IMFCMAMH_01068 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IMFCMAMH_01069 1.1e-34 WQ51_00785 - - - - - - -
IMFCMAMH_01070 6.13e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IMFCMAMH_01071 5.1e-102 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
IMFCMAMH_01072 7.15e-257 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IMFCMAMH_01073 8.37e-257 XK27_07735 - - S - - - YjbR
IMFCMAMH_01074 9.07e-234 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
IMFCMAMH_01075 3.62e-247 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
IMFCMAMH_01076 1.17e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
IMFCMAMH_01077 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMFCMAMH_01078 1.98e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IMFCMAMH_01079 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IMFCMAMH_01080 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IMFCMAMH_01081 2.07e-281 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
IMFCMAMH_01082 2.25e-132 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMFCMAMH_01083 8.38e-193 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IMFCMAMH_01084 6.73e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMFCMAMH_01085 2.97e-86 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IMFCMAMH_01086 1.31e-113 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMFCMAMH_01087 3.8e-190 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
IMFCMAMH_01088 1.85e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMFCMAMH_01089 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
IMFCMAMH_01090 6.56e-188 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMFCMAMH_01091 2e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMFCMAMH_01092 7.21e-191 - - - I - - - Alpha/beta hydrolase family
IMFCMAMH_01093 2.42e-12 - - - - - - - -
IMFCMAMH_01094 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
IMFCMAMH_01095 1.49e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
IMFCMAMH_01096 1.09e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01097 6.3e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IMFCMAMH_01098 3.31e-47 ykuJ - - S - - - protein conserved in bacteria
IMFCMAMH_01099 1.51e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMFCMAMH_01100 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
IMFCMAMH_01101 5.95e-106 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IMFCMAMH_01102 2.23e-65 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
IMFCMAMH_01103 1.42e-219 - - - S - - - oxidoreductase
IMFCMAMH_01104 6.52e-149 - - - M - - - Pfam SNARE associated Golgi protein
IMFCMAMH_01105 5.27e-140 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
IMFCMAMH_01108 9.51e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
IMFCMAMH_01111 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
IMFCMAMH_01112 5.85e-254 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IMFCMAMH_01113 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMFCMAMH_01115 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IMFCMAMH_01116 2.12e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IMFCMAMH_01117 4.35e-19 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
IMFCMAMH_01118 1.5e-40 - - - S - - - Domain of unknown function (DUF1912)
IMFCMAMH_01119 2.28e-223 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
IMFCMAMH_01120 0.0 lysP - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IMFCMAMH_01121 9.58e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IMFCMAMH_01122 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMFCMAMH_01123 2.97e-30 - - - - - - - -
IMFCMAMH_01124 3.34e-117 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMFCMAMH_01125 1.48e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IMFCMAMH_01126 1.13e-273 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
IMFCMAMH_01127 5.64e-294 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
IMFCMAMH_01128 1.08e-102 - - - K - - - hmm pf08876
IMFCMAMH_01129 3.52e-152 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IMFCMAMH_01130 1.64e-39 pspC - - KT - - - PspC domain protein
IMFCMAMH_01131 6.08e-253 - - - S - - - Protein of unknown function (DUF3114)
IMFCMAMH_01132 1.43e-198 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IMFCMAMH_01133 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMFCMAMH_01134 9.45e-317 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
IMFCMAMH_01135 1.21e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
IMFCMAMH_01136 0.0 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
IMFCMAMH_01137 2.1e-151 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMFCMAMH_01138 5.55e-46 - - - - - - - -
IMFCMAMH_01139 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
IMFCMAMH_01140 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMFCMAMH_01141 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
IMFCMAMH_01142 1.7e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IMFCMAMH_01143 1.02e-213 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
IMFCMAMH_01144 1.72e-217 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
IMFCMAMH_01145 2.35e-188 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
IMFCMAMH_01146 9.78e-314 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMFCMAMH_01147 8.59e-162 - - - E - - - Alpha beta hydrolase
IMFCMAMH_01150 7.91e-249 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IMFCMAMH_01151 3.64e-271 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IMFCMAMH_01152 2.2e-162 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IMFCMAMH_01153 3.1e-147 - - - S - - - VIT family
IMFCMAMH_01154 2.46e-172 - - - F - - - Phosphorylase superfamily
IMFCMAMH_01156 3.25e-40 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
IMFCMAMH_01157 3.36e-251 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IMFCMAMH_01158 2.28e-07 - - - S - - - Protein conserved in bacteria
IMFCMAMH_01159 2.68e-160 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IMFCMAMH_01160 1.44e-253 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMFCMAMH_01161 1.98e-280 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
IMFCMAMH_01162 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01163 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01164 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IMFCMAMH_01165 4.21e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
IMFCMAMH_01166 5.56e-19 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01167 1.25e-284 - - - L - - - Phage integrase SAM-like domain
IMFCMAMH_01169 9.79e-275 - - - EP - - - RNA helicase
IMFCMAMH_01170 1.57e-151 - - - D - - - ftsk spoiiie
IMFCMAMH_01174 6.49e-65 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IMFCMAMH_01175 8.41e-102 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMFCMAMH_01176 1.79e-268 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
IMFCMAMH_01177 1.32e-156 salX - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_01178 7.29e-248 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMFCMAMH_01179 8.17e-164 - - - S - - - Putative SAM-dependent methyltransferase
IMFCMAMH_01180 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
IMFCMAMH_01181 1.31e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
IMFCMAMH_01182 5.83e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IMFCMAMH_01183 1.35e-279 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
IMFCMAMH_01184 1.45e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMFCMAMH_01185 1.46e-207 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IMFCMAMH_01186 5.37e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMFCMAMH_01187 2.86e-214 lysR - - K - - - transcriptional regulator (lysR family)
IMFCMAMH_01189 1.32e-90 - - - K - - - Helix-turn-helix
IMFCMAMH_01192 3.03e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMFCMAMH_01193 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_01195 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
IMFCMAMH_01196 7.03e-53 ynzC - - S - - - UPF0291 protein
IMFCMAMH_01197 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IMFCMAMH_01198 1.75e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IMFCMAMH_01199 1.69e-279 - - - S - - - membrane
IMFCMAMH_01200 4.23e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMFCMAMH_01201 0.0 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IMFCMAMH_01202 7.14e-163 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
IMFCMAMH_01203 2.91e-98 - - - S - - - Bacterial inner membrane protein
IMFCMAMH_01204 1.47e-186 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
IMFCMAMH_01205 1.92e-140 - - - S ko:K07023 - ko00000 HD domain
IMFCMAMH_01206 7.61e-139 mur1 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
IMFCMAMH_01207 3.62e-68 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IMFCMAMH_01208 1.17e-289 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
IMFCMAMH_01209 3.3e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMFCMAMH_01210 2e-73 yabA - - L - - - Involved in initiation control of chromosome replication
IMFCMAMH_01211 3.34e-176 yaaT - - S - - - stage 0 sporulation protein
IMFCMAMH_01212 8.77e-204 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
IMFCMAMH_01213 6.62e-140 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMFCMAMH_01215 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMFCMAMH_01216 7.68e-174 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IMFCMAMH_01217 3.2e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMFCMAMH_01218 7.94e-275 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IMFCMAMH_01219 1.24e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IMFCMAMH_01220 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMFCMAMH_01221 3.17e-202 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMFCMAMH_01222 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMFCMAMH_01223 8.62e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMFCMAMH_01224 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMFCMAMH_01225 3e-158 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IMFCMAMH_01226 1.69e-22 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMFCMAMH_01227 2.03e-256 - - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
IMFCMAMH_01229 5.68e-76 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IMFCMAMH_01230 2.69e-92 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
IMFCMAMH_01231 1.84e-281 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMFCMAMH_01232 2.79e-136 - - - M - - - Acetyltransferase (GNAT) domain
IMFCMAMH_01233 2.43e-265 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMFCMAMH_01234 3.85e-206 - - - GK - - - ROK family
IMFCMAMH_01235 4.77e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
IMFCMAMH_01236 4.79e-196 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
IMFCMAMH_01237 7.79e-262 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
IMFCMAMH_01238 3.07e-167 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
IMFCMAMH_01239 4.03e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
IMFCMAMH_01240 9.28e-271 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IMFCMAMH_01241 3.23e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IMFCMAMH_01242 1.33e-105 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMFCMAMH_01243 3.53e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMFCMAMH_01244 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IMFCMAMH_01245 3.54e-186 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMFCMAMH_01246 4.02e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
IMFCMAMH_01247 0.0 ydaO - - E - - - amino acid
IMFCMAMH_01248 1.77e-295 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IMFCMAMH_01249 3.71e-49 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
IMFCMAMH_01250 7.64e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IMFCMAMH_01252 5.9e-255 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IMFCMAMH_01253 2.67e-166 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
IMFCMAMH_01254 1.19e-249 - - - O - - - protein import
IMFCMAMH_01255 2.36e-213 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
IMFCMAMH_01256 3.71e-15 yjdB - - S - - - Domain of unknown function (DUF4767)
IMFCMAMH_01257 1.68e-253 XK27_00915 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMFCMAMH_01259 4.9e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IMFCMAMH_01260 7.88e-94 - - - S - - - QueT transporter
IMFCMAMH_01262 2.1e-223 yfjR - - K - - - regulation of single-species biofilm formation
IMFCMAMH_01264 2.05e-232 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IMFCMAMH_01265 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMFCMAMH_01266 2.71e-154 - - - S - - - AAA ATPase domain
IMFCMAMH_01267 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 DEAD-like helicases superfamily
IMFCMAMH_01268 1.64e-287 sthIM 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
IMFCMAMH_01269 5.2e-164 - - - - - - - -
IMFCMAMH_01270 3.54e-34 - - - - - - - -
IMFCMAMH_01272 3.02e-129 - - - KT - - - MT-A70
IMFCMAMH_01274 0.0 - - - S - - - Type IV secretion-system coupling protein DNA-binding domain
IMFCMAMH_01275 2.67e-147 - - - S - - - Replication-relaxation
IMFCMAMH_01277 0.0 XK27_10845 - - L - - - Domain of unknown function (DUF4368)
IMFCMAMH_01278 3.45e-111 ccl - - S - - - cog cog4708
IMFCMAMH_01279 2.48e-205 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
IMFCMAMH_01280 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IMFCMAMH_01281 4.31e-295 ytoI - - K - - - transcriptional regulator containing CBS domains
IMFCMAMH_01282 8.01e-125 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
IMFCMAMH_01283 1.56e-294 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMFCMAMH_01284 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IMFCMAMH_01285 1.44e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IMFCMAMH_01286 1.98e-180 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
IMFCMAMH_01287 3.1e-210 nodB3 - - G - - - deacetylase
IMFCMAMH_01288 4.27e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
IMFCMAMH_01289 1.14e-53 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IMFCMAMH_01290 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IMFCMAMH_01291 3.84e-203 corA - - P - - - CorA-like protein
IMFCMAMH_01292 1.07e-82 yjqA - - S - - - Bacterial PH domain
IMFCMAMH_01293 9.22e-129 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
IMFCMAMH_01294 1.28e-194 rgg - - K - - - Transcriptional activator, Rgg GadR MutR family
IMFCMAMH_01295 1.32e-242 yjbB - - G - - - Permeases of the major facilitator superfamily
IMFCMAMH_01296 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMFCMAMH_01297 3.53e-150 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
IMFCMAMH_01298 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IMFCMAMH_01302 1.1e-198 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IMFCMAMH_01303 4.44e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01304 1.87e-147 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01305 2.46e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01306 1.31e-245 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IMFCMAMH_01307 5.6e-42 copZ - - P - - - Heavy metal-associated domain protein
IMFCMAMH_01308 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IMFCMAMH_01309 3.52e-96 copY - - K - - - negative regulation of transcription, DNA-templated
IMFCMAMH_01310 3.23e-222 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
IMFCMAMH_01311 7.14e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IMFCMAMH_01312 6.29e-290 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IMFCMAMH_01313 6.98e-125 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
IMFCMAMH_01314 1.08e-170 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IMFCMAMH_01315 3.66e-229 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMFCMAMH_01316 4.1e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
IMFCMAMH_01317 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMFCMAMH_01318 1.03e-55 - 4.2.99.21 - E ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Chorismate mutase type II
IMFCMAMH_01319 6.14e-155 XK27_10210 - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 lipoprotein transporter activity
IMFCMAMH_01320 0.0 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
IMFCMAMH_01321 7.46e-29 - - - S - - - Bacteriocin (Lactococcin_972)
IMFCMAMH_01322 9.98e-78 - - - - - - - -
IMFCMAMH_01323 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
IMFCMAMH_01324 8.15e-62 - - - - - - - -
IMFCMAMH_01327 1.81e-222 - - - L ko:K07482 - ko00000 Integrase
IMFCMAMH_01328 5.31e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMFCMAMH_01330 2.75e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01331 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01332 9.22e-164 - - - K - - - transcriptional regulator, MerR family
IMFCMAMH_01333 1.59e-136 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IMFCMAMH_01334 5.18e-76 WQ51_02910 - - S - - - Protein of unknown function, DUF536
IMFCMAMH_01335 1.81e-82 XK27_02560 - - S - - - cog cog2151
IMFCMAMH_01336 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
IMFCMAMH_01337 3.08e-285 ytfP - - S ko:K07007 - ko00000 Flavoprotein
IMFCMAMH_01339 8.79e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IMFCMAMH_01340 2.95e-197 ytmP - - M - - - Phosphotransferase
IMFCMAMH_01341 2.35e-220 XK27_05910 - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IMFCMAMH_01342 1.38e-167 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01343 3.56e-94 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IMFCMAMH_01346 1.98e-133 - - - - - - - -
IMFCMAMH_01348 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
IMFCMAMH_01350 2.13e-254 ylbM - - S - - - Belongs to the UPF0348 family
IMFCMAMH_01351 2.6e-178 XK27_06665 - - Q - - - Methyltransferase domain protein
IMFCMAMH_01352 5.28e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IMFCMAMH_01353 2.01e-113 yveA - - Q - - - Isochorismatase family
IMFCMAMH_01354 1.17e-136 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IMFCMAMH_01355 2.16e-150 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMFCMAMH_01356 4.57e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
IMFCMAMH_01357 1.27e-271 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IMFCMAMH_01358 4.52e-128 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IMFCMAMH_01359 5.35e-196 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IMFCMAMH_01360 2.32e-82 - - - - - - - -
IMFCMAMH_01361 1.22e-280 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IMFCMAMH_01362 2.78e-73 - - - - - - - -
IMFCMAMH_01363 4.76e-53 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
IMFCMAMH_01364 0.0 celR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IMFCMAMH_01365 4.78e-62 celB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IMFCMAMH_01366 1.09e-42 - - - S ko:K15383 - ko00000,ko02000 PQ loop repeat
IMFCMAMH_01367 0.0 celA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMFCMAMH_01369 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMFCMAMH_01370 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IMFCMAMH_01371 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMFCMAMH_01372 3.16e-57 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
IMFCMAMH_01373 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IMFCMAMH_01374 6.09e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
IMFCMAMH_01375 2.12e-180 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMFCMAMH_01376 4.15e-300 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IMFCMAMH_01377 6.2e-98 XK27_03180 - - T - - - universal stress protein
IMFCMAMH_01379 4.91e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMFCMAMH_01381 1.36e-302 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
IMFCMAMH_01382 2.79e-180 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01383 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
IMFCMAMH_01385 3.01e-125 mraW1 - - J - - - (SAM)-dependent
IMFCMAMH_01386 3.57e-235 ytqA - - S ko:K07139 - ko00000 radical SAM protein
IMFCMAMH_01387 1.77e-239 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IMFCMAMH_01388 5.35e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMFCMAMH_01389 7.69e-120 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IMFCMAMH_01390 1.13e-218 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IMFCMAMH_01391 3.64e-14 - - - S - - - Protein of unknown function (DUF4059)
IMFCMAMH_01392 1.32e-167 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01393 4.88e-209 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01395 6.65e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IMFCMAMH_01397 2.41e-258 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMFCMAMH_01398 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
IMFCMAMH_01400 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
IMFCMAMH_01401 1.34e-187 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
IMFCMAMH_01402 2.81e-99 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IMFCMAMH_01404 6.32e-225 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
IMFCMAMH_01405 5.62e-181 cppA - - E - - - CppA N-terminal
IMFCMAMH_01406 2.14e-138 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IMFCMAMH_01407 7.88e-210 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IMFCMAMH_01408 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IMFCMAMH_01409 2.22e-09 - - - - - - - -
IMFCMAMH_01418 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01419 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01421 9.07e-119 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
IMFCMAMH_01422 7.84e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IMFCMAMH_01423 2.51e-112 yutD - - J - - - protein conserved in bacteria
IMFCMAMH_01424 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMFCMAMH_01426 8.88e-272 - - - T - - - GHKL domain
IMFCMAMH_01427 4.27e-166 lytTr - - KT - - - COG3279 Response regulator of the LytR AlgR family
IMFCMAMH_01428 2.64e-160 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
IMFCMAMH_01429 1.24e-197 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IMFCMAMH_01431 2.64e-302 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IMFCMAMH_01432 2.7e-234 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMFCMAMH_01433 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
IMFCMAMH_01434 5.32e-60 ftsL - - D - - - cell division protein FtsL
IMFCMAMH_01435 7.64e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IMFCMAMH_01438 1.67e-91 - - - J - - - Protein of unknown function (DUF805)
IMFCMAMH_01439 6.32e-86 - - - S - - - Protein of unknown function (DUF805)
IMFCMAMH_01440 3.74e-284 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMFCMAMH_01441 2.37e-180 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMFCMAMH_01442 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
IMFCMAMH_01443 2.59e-172 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01444 1.48e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IMFCMAMH_01445 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IMFCMAMH_01446 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMFCMAMH_01447 1.29e-314 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_01448 1.27e-308 dcuS 2.7.13.3 - T ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
IMFCMAMH_01449 0.0 - - - L - - - Transposase
IMFCMAMH_01450 8.19e-14 - - - - - - - -
IMFCMAMH_01453 2.4e-186 - - - V ko:K21397 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
IMFCMAMH_01455 0.0 - - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 MreB/Mbl protein
IMFCMAMH_01456 9.07e-142 - - - S - - - membrane
IMFCMAMH_01457 1.34e-98 XK27_02470 - - K - - - LytTr DNA-binding domain protein
IMFCMAMH_01458 0.0 - - - KT - - - response to antibiotic
IMFCMAMH_01459 7.41e-189 yebC - - M - - - Membrane
IMFCMAMH_01460 0.0 - - - S - - - hydrolases of the HAD superfamily
IMFCMAMH_01461 2.21e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IMFCMAMH_01463 4.07e-43 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IMFCMAMH_01467 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMFCMAMH_01468 2.44e-246 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMFCMAMH_01469 4.16e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IMFCMAMH_01470 5.23e-249 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMFCMAMH_01471 3.37e-250 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMFCMAMH_01472 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMFCMAMH_01474 2.42e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IMFCMAMH_01475 3.78e-217 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
IMFCMAMH_01476 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_01477 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IMFCMAMH_01478 7.4e-227 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 purine nucleotide biosynthetic process
IMFCMAMH_01479 1.09e-95 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMFCMAMH_01480 7.41e-80 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
IMFCMAMH_01481 8.59e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMFCMAMH_01482 3.59e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IMFCMAMH_01483 6.86e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
IMFCMAMH_01485 2.65e-38 blpT - - - - - - -
IMFCMAMH_01489 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMFCMAMH_01490 2.34e-215 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
IMFCMAMH_01491 9.8e-158 XK27_01040 - - S - - - Protein of unknown function (DUF1129)
IMFCMAMH_01493 4.1e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMFCMAMH_01494 4.18e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IMFCMAMH_01495 6.54e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IMFCMAMH_01496 5.71e-53 XK27_05745 - - - - - - -
IMFCMAMH_01497 5.32e-290 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
IMFCMAMH_01499 0.000678 - - - - - - - -
IMFCMAMH_01500 4.59e-49 - - - - - - - -
IMFCMAMH_01501 1.99e-246 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_01502 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMFCMAMH_01503 2.97e-120 - - - K ko:K14989 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
IMFCMAMH_01504 0.0 - - - T ko:K14988 ko02020,map02020 ko00000,ko00001,ko00002,ko01001,ko02022 Histidine kinase
IMFCMAMH_01505 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01508 2.68e-26 - - - L ko:K07497 - ko00000 Integrase core domain protein
IMFCMAMH_01509 9.6e-290 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01510 8.61e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_01512 9.27e-257 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMFCMAMH_01513 8.95e-273 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
IMFCMAMH_01514 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IMFCMAMH_01515 1.81e-116 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
IMFCMAMH_01516 1.18e-20 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMFCMAMH_01517 4.63e-197 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMFCMAMH_01518 1.76e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IMFCMAMH_01519 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IMFCMAMH_01520 5.89e-63 - - - S - - - branched-chain amino acid
IMFCMAMH_01521 2.7e-143 XK27_12120 - - E - - - AzlC protein
IMFCMAMH_01522 2.23e-236 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMFCMAMH_01523 8.68e-95 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IMFCMAMH_01524 6.03e-150 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
IMFCMAMH_01525 4.54e-45 ykzG - - S - - - Belongs to the UPF0356 family
IMFCMAMH_01526 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMFCMAMH_01527 7.56e-285 - - - L ko:K07485 - ko00000 Transposase
IMFCMAMH_01528 2.42e-147 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
IMFCMAMH_01529 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IMFCMAMH_01530 4e-82 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
IMFCMAMH_01531 1.79e-112 - - - S - - - Fusaric acid resistance protein-like
IMFCMAMH_01532 3.32e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IMFCMAMH_01533 1.06e-155 - - - - - - - -
IMFCMAMH_01534 5.92e-236 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IMFCMAMH_01535 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMFCMAMH_01536 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IMFCMAMH_01537 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMFCMAMH_01538 7.91e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
IMFCMAMH_01539 1.97e-227 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
IMFCMAMH_01540 3.27e-229 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
IMFCMAMH_01541 3.57e-143 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IMFCMAMH_01542 1.15e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IMFCMAMH_01543 2.64e-209 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IMFCMAMH_01545 5.63e-195 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IMFCMAMH_01546 1.49e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMFCMAMH_01547 1.52e-181 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
IMFCMAMH_01548 5.62e-93 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IMFCMAMH_01549 3.11e-67 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IMFCMAMH_01550 9.73e-181 - - - S - - - Macro domain protein
IMFCMAMH_01551 9.05e-78 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
IMFCMAMH_01552 1.55e-68 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
IMFCMAMH_01555 3e-221 - - - L ko:K07482 - ko00000 Integrase
IMFCMAMH_01556 1.58e-285 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IMFCMAMH_01557 6.39e-110 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
IMFCMAMH_01558 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
IMFCMAMH_01559 3.51e-131 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-quinone reductase (modulator of drug activity B)
IMFCMAMH_01560 3.81e-135 - - - K - - - Transcriptional regulator
IMFCMAMH_01561 6.2e-200 jag - - S ko:K06346 - ko00000 RNA-binding protein
IMFCMAMH_01562 1.04e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMFCMAMH_01563 9.69e-72 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IMFCMAMH_01564 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
IMFCMAMH_01565 7.09e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IMFCMAMH_01566 0.0 - - - L - - - Transposase
IMFCMAMH_01567 3.01e-27 - - - U - - - LPXTG cell wall anchor motif
IMFCMAMH_01568 3.69e-141 - - - K - - - Helix-turn-helix domain, rpiR family
IMFCMAMH_01569 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
IMFCMAMH_01570 0.0 - 3.5.1.28 - M ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 domain protein
IMFCMAMH_01571 1.24e-111 - - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01572 1.25e-16 - - - - - - - -
IMFCMAMH_01574 4.48e-92 nisR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IMFCMAMH_01575 2.14e-78 - 2.7.13.3 - T ko:K10681,ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMFCMAMH_01576 2.28e-127 maa 2.3.1.79 - GK ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
IMFCMAMH_01577 3.59e-88 - - - K - - - Transcriptional regulator, MarR family
IMFCMAMH_01578 1.11e-301 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
IMFCMAMH_01579 2.41e-139 - - - S - - - CAAX protease self-immunity
IMFCMAMH_01581 0.0 - - - M ko:K08643 - ko00000,ko01000,ko01002 signal peptide protein, YSIRK family
IMFCMAMH_01582 0.0 - - - GM - - - domain, Protein
IMFCMAMH_01583 8.23e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IMFCMAMH_01584 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
IMFCMAMH_01585 5.95e-32 - 1.3.5.4 - C ko:K00244,ko:K19784 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 reductase
IMFCMAMH_01586 6.08e-202 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 acetyltransferase'
IMFCMAMH_01587 0.0 - - - M - - - family 8
IMFCMAMH_01588 1.7e-201 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 acetyltransferase'
IMFCMAMH_01589 2.14e-301 - - - M - - - Glycosyltransferase, family 8
IMFCMAMH_01590 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IMFCMAMH_01591 4.88e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_01592 6.79e-211 - - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IMFCMAMH_01593 1.94e-236 - - - M - - - transferase activity, transferring glycosyl groups
IMFCMAMH_01594 4.56e-299 - - - M - - - Glycosyltransferase, family 8
IMFCMAMH_01595 3.89e-214 cpsJ - - M - - - Glycosyltransferase group 2 family protein
IMFCMAMH_01596 0.0 - - - M - - - cog cog1442
IMFCMAMH_01597 4.06e-307 - - - M - - - family 8
IMFCMAMH_01598 8.5e-208 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
IMFCMAMH_01599 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
IMFCMAMH_01600 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
IMFCMAMH_01601 3.8e-90 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
IMFCMAMH_01602 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IMFCMAMH_01603 8.08e-16 - - - S - - - Accessory secretory protein Sec Asp4
IMFCMAMH_01604 1.12e-17 - - - S - - - Accessory secretory protein Sec, Asp5
IMFCMAMH_01605 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMFCMAMH_01606 9.69e-254 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IMFCMAMH_01607 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
IMFCMAMH_01608 7.47e-259 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IMFCMAMH_01609 2.11e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IMFCMAMH_01610 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMFCMAMH_01611 7.62e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IMFCMAMH_01612 3.9e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IMFCMAMH_01613 1.36e-05 - - - - - - - -
IMFCMAMH_01614 2.73e-300 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
IMFCMAMH_01615 1.11e-299 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IMFCMAMH_01616 3.15e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IMFCMAMH_01617 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMFCMAMH_01636 1.68e-157 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IMFCMAMH_01637 2.49e-111 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
IMFCMAMH_01638 2.64e-145 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
IMFCMAMH_01639 3.08e-62 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
IMFCMAMH_01640 1.36e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMFCMAMH_01641 3.84e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IMFCMAMH_01642 4.63e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IMFCMAMH_01643 1.19e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IMFCMAMH_01644 1.89e-40 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMFCMAMH_01645 5.24e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IMFCMAMH_01646 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMFCMAMH_01647 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMFCMAMH_01648 2.26e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IMFCMAMH_01649 6.87e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMFCMAMH_01650 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IMFCMAMH_01651 1.52e-301 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IMFCMAMH_01652 7.89e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMFCMAMH_01653 7.74e-257 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMFCMAMH_01654 3.53e-227 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
IMFCMAMH_01655 3.12e-46 - - - - - - - -
IMFCMAMH_01656 3.76e-185 - - - J - - - Domain of unknown function (DUF4041)
IMFCMAMH_01657 2.14e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMFCMAMH_01658 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IMFCMAMH_01659 5.43e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IMFCMAMH_01660 4.46e-74 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IMFCMAMH_01661 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMFCMAMH_01662 1.78e-102 - - - S - - - Protein of unknown function (DUF3021)
IMFCMAMH_01663 2.55e-90 - - - K - - - LytTr DNA-binding domain
IMFCMAMH_01665 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMFCMAMH_01667 1.03e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IMFCMAMH_01668 1.5e-135 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
IMFCMAMH_01669 8.98e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IMFCMAMH_01670 5.07e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMFCMAMH_01671 8.92e-87 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IMFCMAMH_01685 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMFCMAMH_01686 8.78e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IMFCMAMH_01687 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
IMFCMAMH_01688 1.89e-95 - - - K - - - Transcriptional regulator, marr family
IMFCMAMH_01689 5.64e-125 XK27_03570 - - S ko:K19784 - ko00000 reductase
IMFCMAMH_01690 0.0 - - - L - - - Transposase
IMFCMAMH_01692 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase
IMFCMAMH_01693 1.73e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 alkyl hydroperoxide reductase
IMFCMAMH_01694 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IMFCMAMH_01695 1.23e-233 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMFCMAMH_01696 1.69e-107 - - - S - - - Putative small multi-drug export protein
IMFCMAMH_01697 9.88e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IMFCMAMH_01698 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IMFCMAMH_01699 2.47e-298 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IMFCMAMH_01700 5.36e-292 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IMFCMAMH_01701 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IMFCMAMH_01702 3.4e-179 - - - S - - - SseB protein N-terminal domain
IMFCMAMH_01703 6.37e-144 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
IMFCMAMH_01705 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IMFCMAMH_01706 1.22e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMFCMAMH_01708 1.75e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMFCMAMH_01709 2e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IMFCMAMH_01710 1.5e-197 yitS - - S - - - DegV family
IMFCMAMH_01712 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
IMFCMAMH_01713 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMFCMAMH_01714 7.39e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IMFCMAMH_01715 6.65e-245 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_01716 1.1e-116 - - - S - - - Protein conserved in bacteria
IMFCMAMH_01717 1.2e-120 - - - H - - - Methyltransferase
IMFCMAMH_01719 3.02e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
IMFCMAMH_01720 6.89e-123 - - - - - - - -
IMFCMAMH_01721 5.05e-179 srtB 3.4.22.70 - S ko:K08600 - ko00000,ko01000,ko01002,ko01011 sortase, SrtB family
IMFCMAMH_01722 1.49e-295 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
IMFCMAMH_01723 7.18e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
IMFCMAMH_01724 1.27e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
IMFCMAMH_01725 2.4e-168 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
IMFCMAMH_01726 4.28e-182 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IMFCMAMH_01727 9.58e-132 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Muramidase (Flagellum-specific)
IMFCMAMH_01728 1.4e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IMFCMAMH_01729 6.99e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMFCMAMH_01730 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IMFCMAMH_01731 3.64e-133 thiJ-2 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IMFCMAMH_01732 6.04e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IMFCMAMH_01733 1.5e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IMFCMAMH_01734 1.74e-175 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
IMFCMAMH_01735 7.14e-105 hmpT - - S - - - cog cog4720
IMFCMAMH_01748 2.65e-113 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
IMFCMAMH_01749 4.88e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
IMFCMAMH_01750 3.37e-178 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
IMFCMAMH_01751 1.07e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IMFCMAMH_01752 1.24e-101 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IMFCMAMH_01753 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IMFCMAMH_01754 8.37e-108 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
IMFCMAMH_01755 4.36e-98 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
IMFCMAMH_01756 8.61e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
IMFCMAMH_01757 1.13e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IMFCMAMH_01758 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IMFCMAMH_01759 2.43e-88 - - - K - - - AraC-like ligand binding domain
IMFCMAMH_01760 1.22e-229 scrA3 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IMFCMAMH_01761 2.68e-172 - 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
IMFCMAMH_01762 1.1e-293 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
IMFCMAMH_01763 5.82e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
IMFCMAMH_01764 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMFCMAMH_01765 1.42e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IMFCMAMH_01766 0.0 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
IMFCMAMH_01767 5.5e-302 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMFCMAMH_01768 5.97e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IMFCMAMH_01769 3.84e-145 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IMFCMAMH_01770 1.33e-243 XK27_00055 - - P - - - Major Facilitator
IMFCMAMH_01771 3.52e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMFCMAMH_01772 6.41e-127 - - - V - - - VanZ like family
IMFCMAMH_01773 0.0 - - - D - - - nuclear chromosome segregation
IMFCMAMH_01774 0.0 - - - L - - - Transposase
IMFCMAMH_01775 4.26e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01776 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMFCMAMH_01777 1.75e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IMFCMAMH_01779 2.1e-165 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IMFCMAMH_01780 8.98e-242 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
IMFCMAMH_01781 1.65e-176 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IMFCMAMH_01782 5.93e-299 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IMFCMAMH_01783 4.88e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMFCMAMH_01784 2.2e-95 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
IMFCMAMH_01785 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
IMFCMAMH_01786 3.52e-34 - - - - - - - -
IMFCMAMH_01787 2.14e-198 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMFCMAMH_01788 9.8e-233 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMFCMAMH_01789 1.06e-93 adcR - - K - - - transcriptional
IMFCMAMH_01790 3.43e-173 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IMFCMAMH_01791 2.46e-163 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01792 9.07e-204 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
IMFCMAMH_01793 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_01794 4.99e-203 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
IMFCMAMH_01795 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IMFCMAMH_01796 7.66e-193 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_01797 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
IMFCMAMH_01798 4.79e-161 yeeN - - K - - - transcriptional regulatory protein
IMFCMAMH_01799 1.48e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
IMFCMAMH_01800 3.56e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMFCMAMH_01801 2.49e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IMFCMAMH_01802 1.9e-295 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IMFCMAMH_01803 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IMFCMAMH_01804 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
IMFCMAMH_01805 2.47e-182 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01806 6.35e-56 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMFCMAMH_01807 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IMFCMAMH_01809 3.09e-63 - - - - - - - -
IMFCMAMH_01810 2.68e-73 WQ51_06355 - - S - - - TM2 domain
IMFCMAMH_01811 3.47e-209 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IMFCMAMH_01812 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMFCMAMH_01813 2.73e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IMFCMAMH_01814 1.05e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
IMFCMAMH_01815 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IMFCMAMH_01816 1.35e-91 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
IMFCMAMH_01817 8.04e-189 cof - - S - - - Sucrose-6F-phosphate phosphohydrolase
IMFCMAMH_01818 3.77e-171 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
IMFCMAMH_01819 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IMFCMAMH_01820 1.11e-96 napB - - K - - - transcriptional
IMFCMAMH_01821 1.3e-306 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IMFCMAMH_01822 9.06e-62 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IMFCMAMH_01823 8.93e-191 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_01824 1.04e-169 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IMFCMAMH_01825 2.83e-99 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IMFCMAMH_01826 2.54e-42 - - - S - - - Protein of unknown function (DUF3021)
IMFCMAMH_01827 1.6e-158 mta - - K ko:K21743 - ko00000,ko03000 Transcriptional
IMFCMAMH_01828 3.82e-157 - - - V - - - abc transporter atp-binding protein
IMFCMAMH_01829 1.75e-274 - - - V - - - FtsX-like permease family
IMFCMAMH_01830 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMFCMAMH_01831 2.92e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IMFCMAMH_01832 5.35e-102 yhaH - - S - - - Protein of unknown function (DUF805)
IMFCMAMH_01833 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
IMFCMAMH_01834 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IMFCMAMH_01835 1.72e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IMFCMAMH_01836 7.54e-125 ypsA - - S - - - Belongs to the UPF0398 family
IMFCMAMH_01837 4.82e-67 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IMFCMAMH_01838 3.05e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IMFCMAMH_01839 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IMFCMAMH_01840 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
IMFCMAMH_01841 9.47e-28 XK27_11680 - - - - - - -
IMFCMAMH_01842 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IMFCMAMH_01843 5.79e-112 - - - K - - - histone acetyltransferase HPA2 and related acetyltransferases
IMFCMAMH_01844 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMFCMAMH_01845 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IMFCMAMH_01846 9.19e-213 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IMFCMAMH_01847 4.71e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IMFCMAMH_01848 3.95e-168 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMFCMAMH_01849 6.25e-122 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
IMFCMAMH_01850 1.71e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
IMFCMAMH_01852 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IMFCMAMH_01853 3.12e-117 - - - K - - - transcriptional regulator
IMFCMAMH_01854 2.31e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
IMFCMAMH_01855 2.92e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IMFCMAMH_01856 4.69e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMFCMAMH_01857 1.85e-126 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IMFCMAMH_01858 1.81e-113 ykuL - - S - - - CBS domain
IMFCMAMH_01859 2.29e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IMFCMAMH_01860 9.2e-154 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMFCMAMH_01861 1.99e-124 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMFCMAMH_01862 1.23e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IMFCMAMH_01863 2.01e-19 yidD - - M ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IMFCMAMH_01864 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
IMFCMAMH_01865 7.4e-310 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
IMFCMAMH_01866 1.86e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IMFCMAMH_01867 2.29e-116 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMFCMAMH_01868 1.44e-126 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
IMFCMAMH_01869 6.35e-201 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_01870 0.0 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IMFCMAMH_01871 2.12e-70 yhaI - - L - - - Membrane
IMFCMAMH_01872 6.25e-46 - - - S - - - Domain of unknown function (DUF4173)
IMFCMAMH_01873 2.16e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
IMFCMAMH_01874 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IMFCMAMH_01875 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IMFCMAMH_01876 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IMFCMAMH_01877 1.58e-100 ureE - - O ko:K03187 - ko00000 enzyme active site formation
IMFCMAMH_01878 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IMFCMAMH_01879 3.87e-141 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IMFCMAMH_01880 2.84e-203 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IMFCMAMH_01881 1.18e-225 - - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biosynthesis protein CbiM
IMFCMAMH_01882 5.59e-175 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
IMFCMAMH_01883 2.8e-169 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IMFCMAMH_01884 1.73e-185 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IMFCMAMH_01885 1.03e-211 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IMFCMAMH_01886 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IMFCMAMH_01887 1.2e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMFCMAMH_01888 1.27e-152 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_01889 1.47e-267 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IMFCMAMH_01890 6.94e-201 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
IMFCMAMH_01891 7.69e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
IMFCMAMH_01892 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01893 3.54e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
IMFCMAMH_01894 4.66e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IMFCMAMH_01895 2.46e-301 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
IMFCMAMH_01896 2.05e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
IMFCMAMH_01897 6.59e-118 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IMFCMAMH_01898 2.3e-159 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IMFCMAMH_01899 0.0 covS - - T - - - Histidine kinase
IMFCMAMH_01900 1.01e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMFCMAMH_01901 5.84e-273 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
IMFCMAMH_01902 5.12e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IMFCMAMH_01903 5.05e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IMFCMAMH_01904 3.42e-142 - - - - - - - -
IMFCMAMH_01905 1.14e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMFCMAMH_01906 3.08e-81 manO - - S - - - protein conserved in bacteria
IMFCMAMH_01907 6.74e-214 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
IMFCMAMH_01908 2.27e-164 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
IMFCMAMH_01909 5.66e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_01910 4.66e-87 manO - - S - - - Protein conserved in bacteria
IMFCMAMH_01911 2.73e-209 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
IMFCMAMH_01912 6.45e-173 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
IMFCMAMH_01913 1.21e-223 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
IMFCMAMH_01914 6.7e-175 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
IMFCMAMH_01915 2.07e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IMFCMAMH_01916 9.67e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
IMFCMAMH_01917 2.1e-99 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
IMFCMAMH_01918 3.18e-118 XK27_05885 2.3.1.82 - M ko:K18816 - br01600,ko00000,ko01000,ko01504 phosphinothricin N-acetyltransferase activity
IMFCMAMH_01919 1.79e-271 brpA - - K - - - Transcriptional
IMFCMAMH_01920 1.75e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IMFCMAMH_01921 1.37e-258 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IMFCMAMH_01922 9.2e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
IMFCMAMH_01923 1.66e-56 ylxQ - - J - - - ribosomal protein
IMFCMAMH_01924 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMFCMAMH_01925 5.68e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMFCMAMH_01926 1.6e-127 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IMFCMAMH_01927 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMFCMAMH_01928 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
IMFCMAMH_01929 0.0 pacL - - P - - - cation transport ATPase
IMFCMAMH_01930 2.5e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IMFCMAMH_01931 2.85e-287 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IMFCMAMH_01932 0.0 - 3.2.1.26, 3.2.1.65 GH32 G ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IMFCMAMH_01933 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
IMFCMAMH_01934 4.34e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMFCMAMH_01935 1.86e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IMFCMAMH_01936 9.16e-95 ylbF - - S - - - Belongs to the UPF0342 family
IMFCMAMH_01937 8.74e-62 ylbG - - S - - - UPF0298 protein
IMFCMAMH_01938 1.71e-187 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IMFCMAMH_01939 1.99e-39 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IMFCMAMH_01940 1.65e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMFCMAMH_01941 6.66e-184 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IMFCMAMH_01942 2.68e-175 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IMFCMAMH_01943 4.6e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IMFCMAMH_01944 2.67e-144 XK27_04065 - - S ko:K04767 - ko00000 CBS domain
IMFCMAMH_01945 3.47e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IMFCMAMH_01946 1.24e-139 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
IMFCMAMH_01947 1.61e-315 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMFCMAMH_01948 2.01e-112 comFC - - K ko:K02242 - ko00000,ko00002,ko02044 competence protein
IMFCMAMH_01949 4.11e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMFCMAMH_01957 1.16e-213 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
IMFCMAMH_01958 3.15e-141 - - - S - - - Domain of unknown function (DUF1803)
IMFCMAMH_01959 1.99e-132 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IMFCMAMH_01960 1.14e-178 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
IMFCMAMH_01961 2.29e-315 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMFCMAMH_01962 9.93e-243 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
IMFCMAMH_01963 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IMFCMAMH_01964 7.51e-152 yhfA - - S - - - HAD hydrolase, family IA, variant 3
IMFCMAMH_01965 9.24e-179 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
IMFCMAMH_01966 2.67e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
IMFCMAMH_01967 1.04e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMFCMAMH_01968 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMFCMAMH_01969 3.23e-221 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
IMFCMAMH_01970 2.73e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
IMFCMAMH_01971 2.76e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IMFCMAMH_01972 3.69e-297 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IMFCMAMH_01973 1.89e-87 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IMFCMAMH_01974 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IMFCMAMH_01975 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IMFCMAMH_01976 1.71e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMFCMAMH_01977 4.63e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IMFCMAMH_01978 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IMFCMAMH_01979 6.36e-290 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IMFCMAMH_01980 3.6e-161 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
IMFCMAMH_01981 1.3e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IMFCMAMH_01982 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IMFCMAMH_01983 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMFCMAMH_01984 1.94e-286 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IMFCMAMH_01985 1.4e-07 - - - - - - - -
IMFCMAMH_01986 6.46e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IMFCMAMH_01987 1.85e-284 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMFCMAMH_01988 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IMFCMAMH_01989 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IMFCMAMH_01990 1.08e-107 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
IMFCMAMH_01991 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IMFCMAMH_01992 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IMFCMAMH_01993 4.68e-169 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMFCMAMH_01994 2.63e-82 WQ51_03320 - - S - - - cog cog4835
IMFCMAMH_01995 1.88e-188 - - - S - - - EDD domain protein, DegV family
IMFCMAMH_01996 3.01e-177 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IMFCMAMH_01997 6.36e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IMFCMAMH_01998 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_01999 6.23e-30 - - - S - - - Short repeat of unknown function (DUF308)
IMFCMAMH_02000 8.52e-167 - - - F - - - AdP-ribose pyrophosphatase
IMFCMAMH_02001 2.09e-268 nadR - - H - - - adenylyltransferase
IMFCMAMH_02002 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IMFCMAMH_02003 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_02004 7.84e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
IMFCMAMH_02005 1.84e-92 - - - K - - - DNA-binding transcription factor activity
IMFCMAMH_02006 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_02007 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_02008 3.3e-146 - - - K - - - Acetyltransferase (GNAT) family
IMFCMAMH_02009 2.51e-143 - 2.7.6.5 - S ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
IMFCMAMH_02010 1.01e-151 dltr - - T - - - response regulator
IMFCMAMH_02011 1.82e-275 sptS - - T - - - Histidine kinase
IMFCMAMH_02012 2.78e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IMFCMAMH_02013 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IMFCMAMH_02014 4.92e-207 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
IMFCMAMH_02015 2.72e-46 yozE - - S - - - Belongs to the UPF0346 family
IMFCMAMH_02016 2.36e-224 sip - - M - - - LysM domain protein
IMFCMAMH_02017 6e-245 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
IMFCMAMH_02022 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMFCMAMH_02023 5.12e-207 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
IMFCMAMH_02024 3.03e-215 - - - K - - - transcriptional regulator (lysR family)
IMFCMAMH_02025 2.87e-134 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
IMFCMAMH_02026 0.0 - - - S - - - Glucan-binding protein C
IMFCMAMH_02027 3.06e-208 - - - S - - - CHAP domain
IMFCMAMH_02028 3.98e-73 - - - L ko:K07497 - ko00000 Integrase core domain protein
IMFCMAMH_02029 3.16e-102 - - - L - - - transposition
IMFCMAMH_02030 1.92e-237 coiA - - S ko:K06198 - ko00000 Competence protein
IMFCMAMH_02031 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IMFCMAMH_02032 9.09e-280 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IMFCMAMH_02033 3.4e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
IMFCMAMH_02034 3.93e-238 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
IMFCMAMH_02035 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMFCMAMH_02039 3.99e-181 - - - L - - - PFAM transposase IS116 IS110 IS902 family
IMFCMAMH_02040 1.34e-86 - - - L - - - Transposase (IS116 IS110 IS902 family)
IMFCMAMH_02043 8.24e-149 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IMFCMAMH_02044 2.08e-153 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
IMFCMAMH_02045 5.24e-296 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IMFCMAMH_02046 1.28e-174 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
IMFCMAMH_02048 4.28e-101 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
IMFCMAMH_02049 9.05e-85 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IMFCMAMH_02050 2.98e-12 - - - - - - - -
IMFCMAMH_02052 0.0 - - - M - - - GBS Bsp-like repeat
IMFCMAMH_02053 8.7e-179 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
IMFCMAMH_02055 3.4e-173 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
IMFCMAMH_02056 2.5e-296 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IMFCMAMH_02058 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IMFCMAMH_02059 4.73e-184 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IMFCMAMH_02060 6.84e-79 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
IMFCMAMH_02061 1.63e-185 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
IMFCMAMH_02062 2.63e-241 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMFCMAMH_02063 4.5e-280 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMFCMAMH_02064 2.45e-162 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IMFCMAMH_02065 2.83e-261 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IMFCMAMH_02066 2.01e-189 icaB - - G - - - deacetylase
IMFCMAMH_02067 1.47e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IMFCMAMH_02068 2.6e-198 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IMFCMAMH_02069 8.08e-189 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
IMFCMAMH_02071 1.38e-17 coiA - - S ko:K06198 - ko00000 Competence protein
IMFCMAMH_02072 2.11e-139 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMFCMAMH_02073 2.28e-137 rimL - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IMFCMAMH_02074 1.29e-218 - - - S - - - Helix-hairpin-helix DNA-binding motif class 1
IMFCMAMH_02075 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IMFCMAMH_02076 1.11e-105 - - - S - - - AIPR protein
IMFCMAMH_02077 8.18e-79 - - - S - - - AIPR protein
IMFCMAMH_02078 5.9e-74 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
IMFCMAMH_02079 6.23e-149 lrgB - - M - - - Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IMFCMAMH_02080 1.25e-127 - - - S - - - IA, variant 1
IMFCMAMH_02081 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMFCMAMH_02082 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMFCMAMH_02083 4.14e-146 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
IMFCMAMH_02085 2.99e-193 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
IMFCMAMH_02087 1.8e-83 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
IMFCMAMH_02088 2.83e-82 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
IMFCMAMH_02089 6.56e-09 - - - O - - - ADP-ribosylglycohydrolase
IMFCMAMH_02090 8.31e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IMFCMAMH_02091 9.86e-10 - - - S - - - Protein of unknown function (DUF4044)
IMFCMAMH_02092 1.29e-313 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMFCMAMH_02093 5.23e-25 XK27_00735 - - - - - - -
IMFCMAMH_02094 6.86e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
IMFCMAMH_02095 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
IMFCMAMH_02096 2.75e-217 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
IMFCMAMH_02098 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IMFCMAMH_02099 7.49e-110 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
IMFCMAMH_02100 7.65e-183 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
IMFCMAMH_02101 6.55e-179 - - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IMFCMAMH_02102 6.77e-270 arcT - - E - - - Aminotransferase
IMFCMAMH_02103 2.45e-176 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IMFCMAMH_02104 8.61e-28 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IMFCMAMH_02105 2.94e-75 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IMFCMAMH_02106 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IMFCMAMH_02107 2.49e-256 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IMFCMAMH_02108 1.01e-73 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
IMFCMAMH_02109 2.28e-219 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
IMFCMAMH_02110 0.0 - - - S - - - Glucosyl transferase GtrII
IMFCMAMH_02111 4.92e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IMFCMAMH_02112 8.15e-285 - - - S - - - membrane protein involved in the export of O-antigen and teichoic acid
IMFCMAMH_02113 9.9e-240 - - - M - - - Glycosyltransferase group 2 family protein
IMFCMAMH_02114 1.1e-164 arnC - - M ko:K00786 - ko00000,ko01000 group 2 family protein
IMFCMAMH_02115 1.83e-62 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
IMFCMAMH_02116 4.03e-197 - - - S - - - Glycosyltransferase group 2 family protein
IMFCMAMH_02117 0.0 - - - M - - - Glycosyltransferase like family 2
IMFCMAMH_02118 8.84e-285 - - - M - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_02119 3.43e-300 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
IMFCMAMH_02120 0.0 - - - S - - - Glucosyl transferase GtrII
IMFCMAMH_02121 5.51e-287 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
IMFCMAMH_02122 1.23e-225 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
IMFCMAMH_02123 1.09e-181 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IMFCMAMH_02124 9.2e-286 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IMFCMAMH_02125 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
IMFCMAMH_02126 1.32e-153 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IMFCMAMH_02127 3.55e-164 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
IMFCMAMH_02128 7.44e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMFCMAMH_02129 6.19e-79 XK27_04120 - - S - - - Putative amino acid metabolism
IMFCMAMH_02130 1.85e-263 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IMFCMAMH_02131 8.28e-225 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMFCMAMH_02132 3.35e-131 yjbK - - S - - - Adenylate cyclase
IMFCMAMH_02133 2.91e-154 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
IMFCMAMH_02134 5.67e-196 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMFCMAMH_02135 1.05e-219 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IMFCMAMH_02136 9.68e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
IMFCMAMH_02137 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
IMFCMAMH_02138 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
IMFCMAMH_02139 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_02140 4.05e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
IMFCMAMH_02141 1.98e-258 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMFCMAMH_02142 2.87e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IMFCMAMH_02143 2.49e-163 - - - V - - - Psort location CytoplasmicMembrane, score
IMFCMAMH_02144 2.9e-159 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
IMFCMAMH_02145 2.84e-82 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
IMFCMAMH_02146 1.83e-187 - - - S - - - overlaps another CDS with the same product name
IMFCMAMH_02147 4.62e-185 XK27_02985 - - S - - - overlaps another CDS with the same product name
IMFCMAMH_02148 2.62e-279 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IMFCMAMH_02149 3.57e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IMFCMAMH_02150 1.37e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
IMFCMAMH_02151 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMFCMAMH_02152 2.75e-217 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMFCMAMH_02153 1.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMFCMAMH_02154 1.14e-176 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IMFCMAMH_02155 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IMFCMAMH_02156 1.7e-141 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
IMFCMAMH_02157 1.72e-151 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Membrane
IMFCMAMH_02158 1.2e-219 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IMFCMAMH_02159 1.9e-146 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IMFCMAMH_02162 9.14e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMFCMAMH_02163 1.98e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IMFCMAMH_02164 6.99e-242 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IMFCMAMH_02165 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IMFCMAMH_02166 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
IMFCMAMH_02167 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMFCMAMH_02168 1.96e-254 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMFCMAMH_02169 9.06e-243 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 glucose-1-phosphate adenylyltransferase
IMFCMAMH_02170 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IMFCMAMH_02171 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IMFCMAMH_02172 5.18e-128 - - - K - - - Acetyltransferase GNAT Family
IMFCMAMH_02173 0.0 - - - S - - - Protein of unknown function (DUF3114)
IMFCMAMH_02175 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
IMFCMAMH_02176 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_02177 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
IMFCMAMH_02178 4.38e-242 XK27_10075 - - S - - - abc transporter atp-binding protein
IMFCMAMH_02179 0.0 - - - M - - - Pilin isopeptide linkage domain protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)