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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
ICOPOGPD_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICOPOGPD_00002	3.94e-253	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICOPOGPD_00003	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_00004	7.47e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICOPOGPD_00005	1.8e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICOPOGPD_00006	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICOPOGPD_00007	1.87e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
ICOPOGPD_00008	3.9e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
ICOPOGPD_00009	1.36e-05	-	-	-	-	-	-	-	-
ICOPOGPD_00010	9.52e-301	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
ICOPOGPD_00011	3.61e-305	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICOPOGPD_00012	3.15e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICOPOGPD_00013	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICOPOGPD_00032	1.68e-157	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
ICOPOGPD_00033	3.03e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
ICOPOGPD_00034	1.93e-157	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
ICOPOGPD_00035	3.06e-214	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
ICOPOGPD_00036	3.62e-145	-	-	-	L	-	-	-	Helix-turn-helix domain
ICOPOGPD_00037	1.36e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICOPOGPD_00038	1.75e-274	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ICOPOGPD_00039	1.74e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
ICOPOGPD_00040	1.19e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICOPOGPD_00041	9.96e-40	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICOPOGPD_00042	6.12e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
ICOPOGPD_00043	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICOPOGPD_00044	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICOPOGPD_00045	6.46e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
ICOPOGPD_00046	1.63e-127	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICOPOGPD_00047	2.24e-40	-	-	-	-	-	-	-	-
ICOPOGPD_00048	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
ICOPOGPD_00049	1.01e-78	-	-	-	S	-	-	-	AAA ATPase domain
ICOPOGPD_00050	7.23e-15	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Serine/Threonine protein kinases, catalytic domain
ICOPOGPD_00051	1.58e-200	-	-	-	S	-	-	-	CHAP domain
ICOPOGPD_00053	4.25e-21	XK27_10540	-	-	D	-	-	-	Plasmid stabilization system
ICOPOGPD_00054	3.73e-302	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
ICOPOGPD_00055	2.75e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICOPOGPD_00056	1.34e-257	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICOPOGPD_00057	9.3e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
ICOPOGPD_00058	3.12e-46	-	-	-	-	-	-	-	-
ICOPOGPD_00059	2.08e-261	-	-	-	-	-	-	-	-
ICOPOGPD_00060	3.12e-46	-	-	-	-	-	-	-	-
ICOPOGPD_00061	6.12e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICOPOGPD_00062	1.7e-17	-	-	-	-	-	-	-	-
ICOPOGPD_00065	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
ICOPOGPD_00066	5.43e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ICOPOGPD_00067	1.82e-73	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
ICOPOGPD_00068	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICOPOGPD_00069	5.1e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
ICOPOGPD_00070	5.15e-90	-	-	-	K	-	-	-	LytTr DNA-binding domain
ICOPOGPD_00072	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICOPOGPD_00074	1.47e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICOPOGPD_00075	4.37e-134	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
ICOPOGPD_00076	6.49e-288	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
ICOPOGPD_00077	2.41e-259	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICOPOGPD_00078	8.92e-87	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
ICOPOGPD_00092	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICOPOGPD_00093	1.46e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
ICOPOGPD_00094	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
ICOPOGPD_00095	1.89e-95	-	-	-	K	-	-	-	Transcriptional regulator, marr family
ICOPOGPD_00096	1.09e-122	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
ICOPOGPD_00097	1.14e-219	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_00099	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase
ICOPOGPD_00100	1.73e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
ICOPOGPD_00101	1.01e-175	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
ICOPOGPD_00102	1.23e-233	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICOPOGPD_00103	1.69e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
ICOPOGPD_00104	1.15e-98	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
ICOPOGPD_00105	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
ICOPOGPD_00106	3.31e-105	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00107	1.34e-214	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00108	2.47e-298	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ICOPOGPD_00109	5.13e-290	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
ICOPOGPD_00110	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ICOPOGPD_00111	9.73e-179	-	-	-	S	-	-	-	SseB protein N-terminal domain
ICOPOGPD_00112	6.37e-144	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
ICOPOGPD_00114	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
ICOPOGPD_00115	1.22e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICOPOGPD_00117	1.75e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICOPOGPD_00118	2e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
ICOPOGPD_00119	3.03e-197	yitS	-	-	S	-	-	-	DegV family
ICOPOGPD_00120	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00122	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
ICOPOGPD_00123	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICOPOGPD_00124	7.39e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
ICOPOGPD_00125	1.57e-135	yiiE	-	-	S	-	-	-	protein homotetramerization
ICOPOGPD_00126	1.36e-105	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor, CopY TcrY family
ICOPOGPD_00127	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	P-type ATPase
ICOPOGPD_00128	1.34e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_00129	1.2e-120	-	-	-	H	-	-	-	Methyltransferase
ICOPOGPD_00131	3.02e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
ICOPOGPD_00132	6.89e-123	-	-	-	-	-	-	-	-
ICOPOGPD_00133	5.05e-179	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	sortase, SrtB family
ICOPOGPD_00134	1.27e-296	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
ICOPOGPD_00135	3.56e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
ICOPOGPD_00136	1.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
ICOPOGPD_00137	2.4e-168	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
ICOPOGPD_00138	5.21e-183	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
ICOPOGPD_00139	3.9e-131	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Muramidase (Flagellum-specific)
ICOPOGPD_00140	1.34e-236	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICOPOGPD_00141	6.99e-105	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICOPOGPD_00142	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
ICOPOGPD_00144	2.46e-251	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICOPOGPD_00145	1.06e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICOPOGPD_00146	1.01e-174	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
ICOPOGPD_00147	4.13e-104	hmpT	-	-	S	-	-	-	cog cog4720
ICOPOGPD_00160	1.44e-99	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00161	5.57e-115	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
ICOPOGPD_00162	2.47e-180	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
ICOPOGPD_00163	4.46e-293	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICOPOGPD_00164	1.24e-101	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICOPOGPD_00165	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICOPOGPD_00166	1.76e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
ICOPOGPD_00167	2.47e-101	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
ICOPOGPD_00168	8.02e-109	XK27_02675	-	-	K	-	-	-	Acetyltransferase GNAT Family
ICOPOGPD_00169	2.12e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
ICOPOGPD_00170	9.69e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICOPOGPD_00171	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
ICOPOGPD_00172	3.5e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
ICOPOGPD_00173	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICOPOGPD_00174	1.59e-94	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICOPOGPD_00175	0.0	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
ICOPOGPD_00176	5.5e-302	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICOPOGPD_00177	5.97e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICOPOGPD_00178	6.64e-146	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
ICOPOGPD_00179	3.43e-246	XK27_00055	-	-	P	-	-	-	Major Facilitator
ICOPOGPD_00180	3.52e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICOPOGPD_00181	7.48e-126	-	-	-	V	-	-	-	VanZ like family
ICOPOGPD_00182	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
ICOPOGPD_00183	4.26e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00184	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICOPOGPD_00185	1.75e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ICOPOGPD_00187	2.1e-165	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICOPOGPD_00188	7.71e-243	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
ICOPOGPD_00189	1.65e-176	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
ICOPOGPD_00190	5.68e-297	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
ICOPOGPD_00191	4.88e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICOPOGPD_00192	4.28e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
ICOPOGPD_00193	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
ICOPOGPD_00194	2.48e-34	-	-	-	-	-	-	-	-
ICOPOGPD_00195	1.29e-199	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICOPOGPD_00196	9.8e-233	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICOPOGPD_00197	1.5e-93	adcR	-	-	K	-	-	-	transcriptional
ICOPOGPD_00198	1.19e-173	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_00199	2.11e-164	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00200	7.44e-203	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
ICOPOGPD_00201	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_00202	1.67e-201	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
ICOPOGPD_00203	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
ICOPOGPD_00204	8.93e-192	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
ICOPOGPD_00205	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
ICOPOGPD_00206	1.86e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
ICOPOGPD_00207	6.02e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
ICOPOGPD_00208	3.56e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICOPOGPD_00209	7.14e-185	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
ICOPOGPD_00210	7.72e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
ICOPOGPD_00211	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICOPOGPD_00212	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
ICOPOGPD_00213	6.07e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00214	1.1e-56	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICOPOGPD_00215	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICOPOGPD_00216	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00218	1.71e-59	-	-	-	-	-	-	-	-
ICOPOGPD_00219	5.41e-73	WQ51_06355	-	-	S	-	-	-	TM2 domain
ICOPOGPD_00220	1.21e-209	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
ICOPOGPD_00221	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
ICOPOGPD_00222	2.73e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ICOPOGPD_00223	1.05e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
ICOPOGPD_00224	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
ICOPOGPD_00225	9.47e-94	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
ICOPOGPD_00226	3.66e-185	cof	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICOPOGPD_00227	5.36e-171	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
ICOPOGPD_00228	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
ICOPOGPD_00229	1.84e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
ICOPOGPD_00230	7.32e-288	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
ICOPOGPD_00231	2e-65	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
ICOPOGPD_00232	1.19e-65	-	3.2.2.21	-	S	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	YCII-related domain
ICOPOGPD_00233	1.42e-70	-	-	-	K	-	-	-	regulation of RNA biosynthetic process
ICOPOGPD_00234	2.79e-194	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00235	4.53e-180	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
ICOPOGPD_00236	1.92e-97	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
ICOPOGPD_00237	3.63e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
ICOPOGPD_00238	2.66e-157	mta	-	-	K	ko:K21743	-	ko00000,ko03000	Transcriptional
ICOPOGPD_00239	1.82e-155	-	-	-	V	-	-	-	abc transporter atp-binding protein
ICOPOGPD_00240	2.24e-277	-	-	-	V	-	-	-	FtsX-like permease family
ICOPOGPD_00241	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICOPOGPD_00242	2.92e-193	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICOPOGPD_00243	5.35e-102	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
ICOPOGPD_00244	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
ICOPOGPD_00245	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
ICOPOGPD_00246	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICOPOGPD_00247	7.54e-125	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
ICOPOGPD_00248	4.82e-67	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICOPOGPD_00249	2.62e-284	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
ICOPOGPD_00250	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
ICOPOGPD_00251	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
ICOPOGPD_00252	6.74e-28	XK27_11680	-	-	-	-	-	-	-
ICOPOGPD_00253	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
ICOPOGPD_00254	2.19e-116	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
ICOPOGPD_00255	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICOPOGPD_00256	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICOPOGPD_00257	2.63e-212	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICOPOGPD_00258	1.35e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
ICOPOGPD_00259	4.61e-167	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICOPOGPD_00260	2.55e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
ICOPOGPD_00261	1.71e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
ICOPOGPD_00263	1.17e-309	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICOPOGPD_00264	3.12e-117	-	-	-	K	-	-	-	transcriptional regulator
ICOPOGPD_00265	2.31e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
ICOPOGPD_00266	1.39e-190	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
ICOPOGPD_00267	7.78e-235	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICOPOGPD_00268	1.85e-126	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
ICOPOGPD_00269	1.81e-113	ykuL	-	-	S	-	-	-	CBS domain
ICOPOGPD_00270	5.64e-173	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
ICOPOGPD_00271	1.17e-156	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICOPOGPD_00272	1.11e-121	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICOPOGPD_00273	1.23e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ICOPOGPD_00274	4.99e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
ICOPOGPD_00275	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
ICOPOGPD_00276	8.07e-314	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
ICOPOGPD_00277	2.26e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICOPOGPD_00278	1.36e-118	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICOPOGPD_00279	9.68e-141	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
ICOPOGPD_00280	2.03e-197	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
ICOPOGPD_00281	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ICOPOGPD_00282	2.58e-71	yhaI	-	-	L	-	-	-	Membrane
ICOPOGPD_00283	1.97e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
ICOPOGPD_00284	2.16e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
ICOPOGPD_00285	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
ICOPOGPD_00286	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
ICOPOGPD_00287	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
ICOPOGPD_00288	1.58e-100	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
ICOPOGPD_00289	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICOPOGPD_00290	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ICOPOGPD_00291	4.2e-205	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
ICOPOGPD_00292	7.11e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
ICOPOGPD_00293	6.8e-176	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
ICOPOGPD_00294	1.62e-168	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICOPOGPD_00295	1.21e-185	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
ICOPOGPD_00296	2e-209	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
ICOPOGPD_00297	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
ICOPOGPD_00298	2.08e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICOPOGPD_00299	1.04e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00300	5.12e-268	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICOPOGPD_00301	8.45e-202	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
ICOPOGPD_00302	6.32e-122	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
ICOPOGPD_00303	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00304	9.32e-187	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
ICOPOGPD_00305	1.14e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
ICOPOGPD_00306	3e-302	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
ICOPOGPD_00307	1.75e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
ICOPOGPD_00308	5.65e-119	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
ICOPOGPD_00309	2.3e-159	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_00310	0.0	covS	-	-	T	-	-	-	Histidine kinase
ICOPOGPD_00311	1.01e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICOPOGPD_00312	3.02e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
ICOPOGPD_00313	6.23e-213	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
ICOPOGPD_00314	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
ICOPOGPD_00315	2.28e-131	-	-	-	-	-	-	-	-
ICOPOGPD_00316	2.4e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICOPOGPD_00317	7.55e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
ICOPOGPD_00318	4.95e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
ICOPOGPD_00319	5.59e-165	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
ICOPOGPD_00320	1.39e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_00321	1.62e-87	manO	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_00322	1.69e-203	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
ICOPOGPD_00323	6.45e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
ICOPOGPD_00324	7.02e-223	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_00325	1.19e-177	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
ICOPOGPD_00326	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
ICOPOGPD_00327	7.03e-316	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
ICOPOGPD_00328	3.62e-100	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
ICOPOGPD_00329	2.15e-116	XK27_05885	2.3.1.82	-	M	ko:K18816	-	br01600,ko00000,ko01000,ko01504	phosphinothricin N-acetyltransferase activity
ICOPOGPD_00330	7.29e-271	brpA	-	-	K	-	-	-	Transcriptional
ICOPOGPD_00331	1.75e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
ICOPOGPD_00332	1.37e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
ICOPOGPD_00333	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
ICOPOGPD_00334	1.66e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
ICOPOGPD_00335	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICOPOGPD_00336	5.68e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICOPOGPD_00337	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
ICOPOGPD_00338	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICOPOGPD_00339	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
ICOPOGPD_00340	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
ICOPOGPD_00341	5.64e-255	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
ICOPOGPD_00342	6.43e-284	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
ICOPOGPD_00343	0.0	-	3.2.1.26, 3.2.1.65	GH32	G	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
ICOPOGPD_00344	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
ICOPOGPD_00345	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICOPOGPD_00346	3.75e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICOPOGPD_00347	1.11e-95	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
ICOPOGPD_00348	1.51e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
ICOPOGPD_00349	4.35e-271	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
ICOPOGPD_00350	1.65e-189	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICOPOGPD_00351	1.64e-184	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICOPOGPD_00352	2.68e-175	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
ICOPOGPD_00353	1.87e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
ICOPOGPD_00354	2.67e-144	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
ICOPOGPD_00355	3.47e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
ICOPOGPD_00356	3.86e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
ICOPOGPD_00357	9.47e-317	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ICOPOGPD_00358	1.91e-110	comFC	-	-	K	ko:K02242	-	ko00000,ko00002,ko02044	competence protein
ICOPOGPD_00359	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICOPOGPD_00367	2.34e-213	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
ICOPOGPD_00368	7.67e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
ICOPOGPD_00369	1.1e-243	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_00370	1.99e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
ICOPOGPD_00371	9.33e-178	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
ICOPOGPD_00372	2.54e-312	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICOPOGPD_00373	1.53e-244	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
ICOPOGPD_00374	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
ICOPOGPD_00375	3.43e-148	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
ICOPOGPD_00376	9.63e-181	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
ICOPOGPD_00377	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
ICOPOGPD_00378	2.56e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICOPOGPD_00379	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICOPOGPD_00380	3.23e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
ICOPOGPD_00381	1.06e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
ICOPOGPD_00382	5.57e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
ICOPOGPD_00383	3.69e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICOPOGPD_00384	1.85e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICOPOGPD_00385	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICOPOGPD_00386	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
ICOPOGPD_00387	1.99e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICOPOGPD_00388	3.8e-176	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
ICOPOGPD_00389	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICOPOGPD_00390	6.36e-290	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
ICOPOGPD_00391	3.75e-163	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
ICOPOGPD_00392	1.12e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
ICOPOGPD_00393	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
ICOPOGPD_00394	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICOPOGPD_00395	1.02e-297	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
ICOPOGPD_00396	7.4e-07	-	-	-	-	-	-	-	-
ICOPOGPD_00397	1.8e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
ICOPOGPD_00398	1.52e-283	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICOPOGPD_00399	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICOPOGPD_00400	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
ICOPOGPD_00401	6.12e-123	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
ICOPOGPD_00402	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
ICOPOGPD_00403	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
ICOPOGPD_00404	2.07e-172	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICOPOGPD_00405	2.63e-82	WQ51_03320	-	-	S	-	-	-	cog cog4835
ICOPOGPD_00406	6.12e-194	-	-	-	S	-	-	-	EDD domain protein, DegV family
ICOPOGPD_00407	7.1e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICOPOGPD_00408	4.71e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICOPOGPD_00409	4.19e-182	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00410	2.26e-209	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00411	1.56e-30	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
ICOPOGPD_00412	1.79e-168	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
ICOPOGPD_00413	4.82e-257	nadR	-	-	H	-	-	-	adenylyltransferase
ICOPOGPD_00414	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
ICOPOGPD_00415	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00416	6.45e-91	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
ICOPOGPD_00417	6.75e-96	-	-	-	K	-	-	-	DNA-binding transcription factor activity
ICOPOGPD_00418	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00419	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00420	5.48e-145	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
ICOPOGPD_00421	1.25e-143	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
ICOPOGPD_00422	8.64e-153	dltr	-	-	T	-	-	-	response regulator
ICOPOGPD_00423	4.46e-276	sptS	-	-	T	-	-	-	Histidine kinase
ICOPOGPD_00424	2.78e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
ICOPOGPD_00425	7.89e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICOPOGPD_00426	4.92e-207	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
ICOPOGPD_00427	2.72e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
ICOPOGPD_00428	1.88e-212	sip	-	-	M	-	-	-	LysM domain protein
ICOPOGPD_00429	6.93e-239	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
ICOPOGPD_00433	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICOPOGPD_00434	5.12e-207	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
ICOPOGPD_00435	3.03e-215	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
ICOPOGPD_00436	2.87e-134	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
ICOPOGPD_00437	0.0	-	-	-	S	-	-	-	Glucan-binding protein C
ICOPOGPD_00438	2.42e-205	-	-	-	S	-	-	-	CHAP domain
ICOPOGPD_00439	9.78e-118	-	-	-	L	ko:K07497	-	ko00000	overlaps another CDS with the same product name
ICOPOGPD_00440	8.12e-45	-	-	-	L	-	-	-	transposition
ICOPOGPD_00441	7.18e-233	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
ICOPOGPD_00442	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
ICOPOGPD_00443	1.18e-275	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
ICOPOGPD_00444	3.96e-163	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
ICOPOGPD_00445	3.93e-238	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
ICOPOGPD_00446	1.09e-110	XK27_03390	-	-	S	-	-	-	LURP-one-related
ICOPOGPD_00447	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICOPOGPD_00448	1.65e-54	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00449	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_00451	1e-149	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
ICOPOGPD_00452	3.59e-154	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
ICOPOGPD_00453	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00455	5.48e-298	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ICOPOGPD_00456	1.28e-174	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
ICOPOGPD_00459	6.12e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00460	5.24e-84	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
ICOPOGPD_00461	2.98e-12	-	-	-	-	-	-	-	-
ICOPOGPD_00463	0.0	-	-	-	M	-	-	-	GBS Bsp-like repeat
ICOPOGPD_00464	8.7e-179	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
ICOPOGPD_00466	2.8e-172	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
ICOPOGPD_00467	9.73e-294	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ICOPOGPD_00469	0.0	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
ICOPOGPD_00470	3.25e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ICOPOGPD_00471	6.75e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
ICOPOGPD_00472	1.78e-239	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICOPOGPD_00473	5.48e-281	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ICOPOGPD_00474	6.02e-163	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICOPOGPD_00475	4.89e-262	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
ICOPOGPD_00476	2.01e-189	icaB	-	-	G	-	-	-	deacetylase
ICOPOGPD_00477	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
ICOPOGPD_00478	1.18e-194	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICOPOGPD_00479	4.18e-191	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
ICOPOGPD_00481	1.38e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
ICOPOGPD_00482	2.02e-137	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICOPOGPD_00483	3.95e-138	rimL	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICOPOGPD_00484	1.43e-215	-	-	-	S	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
ICOPOGPD_00485	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICOPOGPD_00486	5.31e-200	-	-	-	S	-	-	-	AIPR protein
ICOPOGPD_00487	5.9e-74	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
ICOPOGPD_00488	5.34e-150	lrgB	-	-	M	-	-	-	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ICOPOGPD_00489	1.03e-126	-	-	-	S	-	-	-	IA, variant 1
ICOPOGPD_00490	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICOPOGPD_00491	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICOPOGPD_00492	4.14e-146	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
ICOPOGPD_00494	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00495	1.97e-194	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
ICOPOGPD_00497	1.8e-83	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
ICOPOGPD_00498	2.83e-82	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
ICOPOGPD_00499	6.56e-09	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
ICOPOGPD_00500	8.31e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ICOPOGPD_00501	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
ICOPOGPD_00502	1.29e-313	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICOPOGPD_00503	5.23e-25	XK27_00735	-	-	-	-	-	-	-
ICOPOGPD_00504	6.86e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00505	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICOPOGPD_00506	2.75e-217	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
ICOPOGPD_00508	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICOPOGPD_00509	2.76e-115	yfbM	-	-	K	-	-	-	Gnat family
ICOPOGPD_00510	5.98e-77	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
ICOPOGPD_00511	7.09e-25	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICOPOGPD_00512	3.05e-109	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
ICOPOGPD_00513	7.65e-183	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
ICOPOGPD_00514	6.55e-179	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
ICOPOGPD_00515	1.94e-269	arcT	-	-	E	-	-	-	Aminotransferase
ICOPOGPD_00516	9.99e-176	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
ICOPOGPD_00517	8.61e-28	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
ICOPOGPD_00518	1.91e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICOPOGPD_00519	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICOPOGPD_00520	2.49e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICOPOGPD_00521	1.01e-73	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
ICOPOGPD_00522	1.6e-219	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
ICOPOGPD_00523	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
ICOPOGPD_00524	5.74e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICOPOGPD_00525	1.44e-277	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
ICOPOGPD_00526	7.8e-237	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
ICOPOGPD_00527	1.1e-164	arnC	-	-	M	ko:K00786	-	ko00000,ko01000	group 2 family protein
ICOPOGPD_00528	1.83e-62	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
ICOPOGPD_00529	4.03e-197	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
ICOPOGPD_00530	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
ICOPOGPD_00531	4.38e-285	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00532	5.09e-302	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
ICOPOGPD_00533	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
ICOPOGPD_00534	5.51e-287	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
ICOPOGPD_00535	2.12e-226	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
ICOPOGPD_00536	1.09e-181	-	-	-	GM	ko:K01992,ko:K09690,ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
ICOPOGPD_00537	1.52e-284	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ICOPOGPD_00538	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
ICOPOGPD_00539	7.66e-153	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
ICOPOGPD_00540	5.88e-163	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
ICOPOGPD_00541	9.05e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICOPOGPD_00542	1.52e-79	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
ICOPOGPD_00543	4.17e-260	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
ICOPOGPD_00544	2.37e-224	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICOPOGPD_00545	5.34e-128	yjbK	-	-	S	-	-	-	Adenylate cyclase
ICOPOGPD_00546	2.91e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
ICOPOGPD_00547	3.99e-196	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICOPOGPD_00548	6.05e-219	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
ICOPOGPD_00549	5.23e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
ICOPOGPD_00550	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
ICOPOGPD_00551	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
ICOPOGPD_00552	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00553	4.05e-213	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00554	6.62e-257	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ICOPOGPD_00555	2.87e-218	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ICOPOGPD_00556	3.78e-158	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00557	5.01e-160	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00558	8.13e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
ICOPOGPD_00559	6.64e-190	-	-	-	S	-	-	-	overlaps another CDS with the same product name
ICOPOGPD_00560	1.23e-189	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
ICOPOGPD_00561	4.19e-262	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICOPOGPD_00562	4.34e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
ICOPOGPD_00563	3.93e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
ICOPOGPD_00564	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICOPOGPD_00565	5.8e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICOPOGPD_00566	5.62e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICOPOGPD_00567	1.14e-176	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
ICOPOGPD_00568	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
ICOPOGPD_00569	2.42e-141	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
ICOPOGPD_00570	4.94e-151	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Membrane
ICOPOGPD_00571	1.46e-220	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICOPOGPD_00572	1.9e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICOPOGPD_00575	1.85e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICOPOGPD_00576	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
ICOPOGPD_00577	2e-241	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
ICOPOGPD_00578	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
ICOPOGPD_00579	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
ICOPOGPD_00580	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICOPOGPD_00581	1.61e-253	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ICOPOGPD_00582	1.5e-241	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase
ICOPOGPD_00583	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
ICOPOGPD_00584	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ICOPOGPD_00585	5.18e-128	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
ICOPOGPD_00586	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
ICOPOGPD_00588	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
ICOPOGPD_00589	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00590	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00591	3.08e-242	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
ICOPOGPD_00592	0.0	-	-	-	M	-	-	-	Pilin isopeptide linkage domain protein
ICOPOGPD_00593	0.0	-	-	-	M	-	-	-	Pilin isopeptide linkage domain protein
ICOPOGPD_00594	0.0	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	signal peptide protein, YSIRK family
ICOPOGPD_00595	0.0	-	-	-	GM	-	-	-	domain, Protein
ICOPOGPD_00596	1.12e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICOPOGPD_00597	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
ICOPOGPD_00600	6.08e-202	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	acetyltransferase'
ICOPOGPD_00601	0.0	-	-	-	M	-	-	-	family 8
ICOPOGPD_00602	2.51e-203	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	acetyltransferase'
ICOPOGPD_00603	1.99e-306	-	-	-	M	-	-	-	Glycosyltransferase, family 8
ICOPOGPD_00604	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICOPOGPD_00605	4.75e-247	-	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
ICOPOGPD_00606	4.78e-237	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
ICOPOGPD_00607	2.36e-301	-	-	-	M	-	-	-	Glycosyltransferase, family 8
ICOPOGPD_00608	9.55e-215	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
ICOPOGPD_00609	0.0	-	-	-	M	-	-	-	cog cog1442
ICOPOGPD_00610	2.35e-306	-	-	-	M	-	-	-	family 8
ICOPOGPD_00611	8.5e-208	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
ICOPOGPD_00612	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
ICOPOGPD_00613	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
ICOPOGPD_00614	3.8e-90	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
ICOPOGPD_00615	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICOPOGPD_00616	8.08e-16	-	-	-	S	-	-	-	Accessory secretory protein Sec Asp4
ICOPOGPD_00617	1.59e-17	-	-	-	S	-	-	-	Accessory secretory protein Sec, Asp5
ICOPOGPD_00622	8.64e-33	-	-	-	U	-	-	-	LPXTG cell wall anchor motif
ICOPOGPD_00623	2.92e-153	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
ICOPOGPD_00624	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_00625	0.0	-	3.5.1.28	-	M	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	domain protein
ICOPOGPD_00626	1.87e-126	maa	2.3.1.79	-	GK	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
ICOPOGPD_00627	2.08e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
ICOPOGPD_00628	2.61e-300	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
ICOPOGPD_00629	3.35e-168	-	-	-	S	-	-	-	CAAX protease self-immunity
ICOPOGPD_00631	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00632	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00633	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
ICOPOGPD_00634	3.39e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ICOPOGPD_00635	6.71e-134	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ICOPOGPD_00636	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00637	0.0	tcdB	-	-	S	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	dextransucrase activity
ICOPOGPD_00638	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
ICOPOGPD_00639	2.02e-105	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
ICOPOGPD_00640	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00641	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00642	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00643	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_00644	5.4e-24	-	-	-	-	-	-	-	-
ICOPOGPD_00645	8.28e-97	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family
ICOPOGPD_00646	8.61e-188	-	-	-	L	ko:K07485	-	ko00000	Transposase
ICOPOGPD_00647	4.4e-40	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
ICOPOGPD_00648	5.98e-209	scnK	-	-	T	-	-	-	Histidine kinase
ICOPOGPD_00649	2.65e-123	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_00651	0.0	lcnDR2	-	-	V	-	-	-	Domain of unknown function (DUF4135)
ICOPOGPD_00652	3.59e-289	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	Lantibiotic transport processing ATP-binding protein
ICOPOGPD_00653	3.58e-151	bcrA	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00654	1.14e-100	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
ICOPOGPD_00655	2.99e-88	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
ICOPOGPD_00656	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00657	1.12e-143	-	-	-	L	ko:K07487	-	ko00000	Transposase
ICOPOGPD_00658	1.49e-90	-	-	-	L	ko:K07487	-	ko00000	Transposase
ICOPOGPD_00659	2.5e-107	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
ICOPOGPD_00660	3.27e-239	-	-	-	I	-	-	-	radical SAM domain protein
ICOPOGPD_00661	6.25e-227	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
ICOPOGPD_00662	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_00663	6.74e-144	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
ICOPOGPD_00664	4.94e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
ICOPOGPD_00665	2.93e-14	-	-	-	S	-	-	-	integral membrane protein
ICOPOGPD_00666	1.8e-246	mccF	-	-	V	-	-	-	LD-carboxypeptidase
ICOPOGPD_00667	3.93e-12	-	-	-	S	-	-	-	Enterocin A Immunity
ICOPOGPD_00668	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
ICOPOGPD_00669	5.11e-46	-	-	-	S	-	-	-	Immunity protein 41
ICOPOGPD_00670	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
ICOPOGPD_00671	1.21e-287	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00672	1.23e-229	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
ICOPOGPD_00673	1.41e-123	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
ICOPOGPD_00674	2e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	dihydroxyacetone kinase, phosphotransfer subunit
ICOPOGPD_00675	6.1e-229	XK27_10475	-	-	S	-	-	-	oxidoreductase
ICOPOGPD_00676	9.96e-41	-	-	-	P	-	-	-	oxidoreductase
ICOPOGPD_00677	6.28e-203	-	-	-	P	-	-	-	oxidoreductase
ICOPOGPD_00678	2.14e-06	-	-	-	-	-	-	-	-
ICOPOGPD_00679	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
ICOPOGPD_00680	6.68e-268	vex1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
ICOPOGPD_00681	9.74e-138	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00682	4.77e-306	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
ICOPOGPD_00683	1.06e-149	vncR	-	-	K	-	-	-	Response regulator receiver domain protein
ICOPOGPD_00684	3.34e-287	vncS	2.7.13.3	-	T	ko:K10819	-	ko00000,ko01000	Histidine kinase
ICOPOGPD_00685	3.06e-214	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
ICOPOGPD_00686	3.62e-145	-	-	-	L	-	-	-	Helix-turn-helix domain
ICOPOGPD_00687	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	COG0366 Glycosidases
ICOPOGPD_00688	1.1e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ICOPOGPD_00689	6.67e-282	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICOPOGPD_00690	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
ICOPOGPD_00691	2.87e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICOPOGPD_00692	6.32e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
ICOPOGPD_00693	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
ICOPOGPD_00694	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
ICOPOGPD_00695	2.96e-132	-	-	-	S	-	-	-	Tetratricopeptide repeat
ICOPOGPD_00696	8.27e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
ICOPOGPD_00697	1.34e-197	yvgN	-	-	C	-	-	-	reductase
ICOPOGPD_00698	1.47e-41	XK27_10490	-	-	-	-	-	-	-
ICOPOGPD_00699	8.33e-53	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	nuclease activity
ICOPOGPD_00700	5.2e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
ICOPOGPD_00701	2.39e-138	yodC	-	-	C	-	-	-	nitroreductase
ICOPOGPD_00702	2.73e-284	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICOPOGPD_00703	2.81e-198	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
ICOPOGPD_00704	1.72e-99	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_00705	5.03e-195	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
ICOPOGPD_00706	1.93e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
ICOPOGPD_00707	1.04e-51	-	-	-	-	-	-	-	-
ICOPOGPD_00708	1.39e-36	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	transcriptional
ICOPOGPD_00710	3.49e-218	ydhF	-	-	S	-	-	-	Aldo keto reductase
ICOPOGPD_00711	9.32e-126	-	-	-	K	-	-	-	WHG domain
ICOPOGPD_00712	2.13e-158	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00713	5.43e-257	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
ICOPOGPD_00714	1.39e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
ICOPOGPD_00715	7.66e-106	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
ICOPOGPD_00716	5.95e-218	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
ICOPOGPD_00717	8.21e-212	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
ICOPOGPD_00718	1.59e-146	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00719	3.2e-145	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
ICOPOGPD_00720	3.96e-177	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00722	7.04e-63	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00723	0.0	-	-	-	S	-	-	-	dextransucrase activity
ICOPOGPD_00724	9.72e-296	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
ICOPOGPD_00725	4.18e-67	-	-	-	S	-	-	-	ASCH
ICOPOGPD_00726	3.63e-265	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
ICOPOGPD_00727	1.3e-32	-	-	-	S	-	-	-	CsbD-like
ICOPOGPD_00728	1.68e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
ICOPOGPD_00729	1.03e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
ICOPOGPD_00730	2.5e-230	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
ICOPOGPD_00731	3.85e-297	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
ICOPOGPD_00732	1.9e-231	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICOPOGPD_00734	4.28e-309	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
ICOPOGPD_00735	9.24e-183	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
ICOPOGPD_00736	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
ICOPOGPD_00737	1.33e-77	pdxH	-	-	S	-	-	-	pyridoxamine 5'-phosphate oxidase
ICOPOGPD_00738	1.47e-284	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
ICOPOGPD_00739	1.03e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICOPOGPD_00740	4.3e-158	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_00741	3.4e-205	-	-	-	T	-	-	-	Histidine kinase
ICOPOGPD_00742	4.97e-170	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_00743	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
ICOPOGPD_00744	1.17e-120	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
ICOPOGPD_00747	6.91e-202	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00748	8.31e-170	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transporter
ICOPOGPD_00749	2.01e-107	-	-	-	F	-	-	-	cytidine deaminase activity
ICOPOGPD_00750	3.06e-212	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
ICOPOGPD_00753	1.7e-202	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
ICOPOGPD_00754	2.04e-170	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
ICOPOGPD_00755	2.16e-243	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICOPOGPD_00756	6.93e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICOPOGPD_00757	4.43e-110	-	-	-	-	-	-	-	-
ICOPOGPD_00758	2.68e-129	-	-	-	-	-	-	-	-
ICOPOGPD_00759	2.51e-62	-	-	-	-	-	-	-	-
ICOPOGPD_00760	8.18e-305	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00761	8.06e-104	-	-	-	S	-	-	-	RDD family
ICOPOGPD_00762	3.18e-209	yjlA	-	-	EG	-	-	-	membrane
ICOPOGPD_00763	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
ICOPOGPD_00764	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00765	1.43e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
ICOPOGPD_00766	8.05e-157	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
ICOPOGPD_00767	9.26e-132	-	-	-	-	-	-	-	-
ICOPOGPD_00768	8.21e-168	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
ICOPOGPD_00769	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICOPOGPD_00770	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICOPOGPD_00771	7.32e-115	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
ICOPOGPD_00772	0.0	clsA_1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICOPOGPD_00773	3.18e-160	alkD	-	-	L	-	-	-	Dna alkylation repair
ICOPOGPD_00774	1.44e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICOPOGPD_00775	8.96e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICOPOGPD_00776	2.63e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICOPOGPD_00777	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
ICOPOGPD_00778	1.37e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
ICOPOGPD_00779	1.06e-31	WQ51_00220	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
ICOPOGPD_00780	1.96e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICOPOGPD_00781	3.44e-117	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICOPOGPD_00782	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICOPOGPD_00784	6.52e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
ICOPOGPD_00785	6.51e-308	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICOPOGPD_00787	6.67e-109	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
ICOPOGPD_00788	2.95e-183	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
ICOPOGPD_00789	4.61e-108	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
ICOPOGPD_00790	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
ICOPOGPD_00791	0.0	noxE	-	-	P	-	-	-	NADH oxidase
ICOPOGPD_00792	7.17e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
ICOPOGPD_00793	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICOPOGPD_00794	9.28e-171	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
ICOPOGPD_00795	2.31e-97	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
ICOPOGPD_00796	1.62e-210	ypuA	-	-	S	-	-	-	secreted protein
ICOPOGPD_00797	1.28e-293	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
ICOPOGPD_00798	3.52e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
ICOPOGPD_00799	3.37e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICOPOGPD_00800	2.04e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
ICOPOGPD_00801	4.17e-192	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
ICOPOGPD_00802	3.42e-235	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ICOPOGPD_00803	2.35e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
ICOPOGPD_00804	7.92e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICOPOGPD_00805	6.79e-185	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICOPOGPD_00806	3.04e-130	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICOPOGPD_00807	4.08e-82	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
ICOPOGPD_00808	9.36e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICOPOGPD_00809	1.5e-228	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
ICOPOGPD_00810	5.07e-127	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
ICOPOGPD_00811	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00812	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00813	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICOPOGPD_00814	5.94e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
ICOPOGPD_00815	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICOPOGPD_00816	5.4e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICOPOGPD_00817	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
ICOPOGPD_00818	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
ICOPOGPD_00820	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICOPOGPD_00821	2.97e-211	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
ICOPOGPD_00822	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
ICOPOGPD_00823	1.72e-117	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00824	1.07e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
ICOPOGPD_00825	8.28e-118	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICOPOGPD_00826	1.67e-151	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
ICOPOGPD_00827	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
ICOPOGPD_00828	3.97e-153	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_00829	2.77e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICOPOGPD_00830	4.36e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
ICOPOGPD_00831	9.34e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
ICOPOGPD_00832	4.38e-134	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
ICOPOGPD_00833	9.76e-297	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
ICOPOGPD_00834	2.03e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICOPOGPD_00835	4.08e-83	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ICOPOGPD_00836	1.72e-245	-	-	-	S	ko:K07335	-	ko00000	membrane
ICOPOGPD_00837	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_00838	1.5e-234	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICOPOGPD_00839	8.2e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICOPOGPD_00840	1.58e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
ICOPOGPD_00841	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
ICOPOGPD_00842	1.32e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_00843	6.82e-273	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
ICOPOGPD_00844	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
ICOPOGPD_00846	6e-254	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
ICOPOGPD_00847	9.11e-84	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
ICOPOGPD_00848	4.52e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICOPOGPD_00849	2.02e-106	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
ICOPOGPD_00850	8.72e-173	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
ICOPOGPD_00851	5.6e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
ICOPOGPD_00852	1.14e-301	-	-	-	D	-	-	-	nuclear chromosome segregation
ICOPOGPD_00853	3.8e-176	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
ICOPOGPD_00854	1.78e-210	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
ICOPOGPD_00855	1.06e-232	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
ICOPOGPD_00856	1.99e-206	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
ICOPOGPD_00857	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
ICOPOGPD_00858	1.56e-188	XK27_10720	-	-	D	-	-	-	peptidase activity
ICOPOGPD_00859	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ICOPOGPD_00862	1.24e-216	yeiH	-	-	S	-	-	-	Membrane
ICOPOGPD_00863	3.54e-167	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
ICOPOGPD_00864	5.13e-213	cpsY	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_00865	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICOPOGPD_00866	7.1e-78	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
ICOPOGPD_00867	1.17e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00868	2.61e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00869	1.35e-203	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
ICOPOGPD_00870	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICOPOGPD_00871	1.24e-67	-	-	-	-	-	-	-	-
ICOPOGPD_00872	4.33e-62	-	-	-	-	-	-	-	-
ICOPOGPD_00873	1.55e-74	adhP	1.1.1.1	-	P	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ICOPOGPD_00874	3.26e-90	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
ICOPOGPD_00875	2.44e-130	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICOPOGPD_00876	1.32e-235	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_00877	5.44e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
ICOPOGPD_00878	3.07e-71	-	-	-	S	-	-	-	ABC-2 type transporter
ICOPOGPD_00879	4.58e-127	-	-	-	-	-	-	-	-
ICOPOGPD_00880	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
ICOPOGPD_00881	5.22e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
ICOPOGPD_00882	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICOPOGPD_00883	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICOPOGPD_00884	1.33e-111	-	-	-	-	ko:K16788	-	ko00000,ko02000	-
ICOPOGPD_00885	2.73e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
ICOPOGPD_00886	4.32e-164	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
ICOPOGPD_00887	1.4e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICOPOGPD_00888	8.95e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICOPOGPD_00889	6.15e-207	-	-	-	GK	-	-	-	ROK family
ICOPOGPD_00890	5.28e-199	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
ICOPOGPD_00891	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICOPOGPD_00892	1.47e-106	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
ICOPOGPD_00893	4.94e-66	-	-	-	V	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
ICOPOGPD_00895	1.34e-194	-	-	-	S	-	-	-	TraX protein
ICOPOGPD_00896	7.75e-153	yycF1	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_00897	4.04e-294	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
ICOPOGPD_00898	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ICOPOGPD_00899	9.05e-108	XK27_05470	-	-	E	-	-	-	Methionine synthase
ICOPOGPD_00900	3.89e-141	XK27_05470	-	-	E	-	-	-	Methionine synthase
ICOPOGPD_00901	1.51e-74	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
ICOPOGPD_00902	0.0	-	-	-	V	ko:K13732	ko05100,map05100	ko00000,ko00001	Glucan-binding protein C
ICOPOGPD_00903	9.73e-155	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICOPOGPD_00904	7.38e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICOPOGPD_00905	2.69e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
ICOPOGPD_00906	2.92e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICOPOGPD_00907	8.32e-229	-	-	-	P	-	-	-	Chloride transporter, ClC family
ICOPOGPD_00908	2.31e-172	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
ICOPOGPD_00909	6.86e-169	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
ICOPOGPD_00910	4.79e-27	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00912	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICOPOGPD_00916	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
ICOPOGPD_00917	1.9e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
ICOPOGPD_00918	7.25e-53	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
ICOPOGPD_00919	6.36e-123	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
ICOPOGPD_00920	3.41e-98	-	-	-	S	-	-	-	Macro domain
ICOPOGPD_00921	1.4e-89	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
ICOPOGPD_00922	3.48e-186	-	-	-	GM	-	-	-	NmrA-like family
ICOPOGPD_00923	1.05e-166	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00924	0.0	proWX	-	-	P	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICOPOGPD_00925	2.15e-153	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00926	6.63e-213	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
ICOPOGPD_00927	1.21e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICOPOGPD_00928	2.08e-76	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00929	6.31e-105	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00930	2.77e-22	-	-	-	L	-	-	-	Transposase
ICOPOGPD_00931	4.43e-91	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICOPOGPD_00932	0.0	-	-	-	P	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
ICOPOGPD_00933	0.0	-	-	-	P	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
ICOPOGPD_00934	7.47e-104	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
ICOPOGPD_00935	4.53e-111	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
ICOPOGPD_00936	3.86e-233	-	-	-	P	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
ICOPOGPD_00937	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00938	4.26e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_00939	2.1e-118	tetR	-	-	K	-	-	-	transcriptional regulator
ICOPOGPD_00940	6.49e-177	-	-	-	S	-	-	-	Phenazine biosynthesis protein
ICOPOGPD_00941	1.23e-126	-	2.7.7.65	-	T	ko:K16923,ko:K18967	-	ko00000,ko00002,ko01000,ko02000	phosphorelay sensor kinase activity
ICOPOGPD_00942	3.45e-169	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
ICOPOGPD_00943	5.3e-203	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_00944	1.15e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'abc transporter, ATP-binding protein
ICOPOGPD_00945	1.14e-52	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
ICOPOGPD_00946	9.27e-249	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
ICOPOGPD_00947	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
ICOPOGPD_00948	4.08e-216	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
ICOPOGPD_00950	3.49e-91	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
ICOPOGPD_00951	1.18e-121	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
ICOPOGPD_00952	3.87e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
ICOPOGPD_00953	7.87e-246	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
ICOPOGPD_00954	5.91e-236	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
ICOPOGPD_00955	1.05e-63	lysR	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_00956	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_00957	1.74e-115	lysR	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_00958	2.7e-230	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
ICOPOGPD_00959	6.02e-188	-	-	-	G	-	-	-	protein with an alpha beta hydrolase fold
ICOPOGPD_00960	1.17e-169	-	-	-	F	-	-	-	Phosphorylase superfamily
ICOPOGPD_00961	2.69e-140	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
ICOPOGPD_00962	4.67e-175	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
ICOPOGPD_00963	8.34e-229	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
ICOPOGPD_00964	3.62e-145	-	-	-	L	-	-	-	Helix-turn-helix domain
ICOPOGPD_00965	3.06e-214	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
ICOPOGPD_00966	1.13e-283	dinF	-	-	V	-	-	-	Mate efflux family protein
ICOPOGPD_00967	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_00968	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
ICOPOGPD_00969	7.53e-172	-	-	-	S	-	-	-	TraX protein
ICOPOGPD_00970	9.3e-120	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
ICOPOGPD_00971	2.21e-185	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
ICOPOGPD_00972	3.25e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICOPOGPD_00973	8.35e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICOPOGPD_00974	3.05e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICOPOGPD_00975	8.17e-306	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
ICOPOGPD_00976	4.62e-190	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
ICOPOGPD_00977	3.79e-104	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_00978	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
ICOPOGPD_00979	1.57e-224	bglC	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_00980	6.62e-312	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICOPOGPD_00981	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_00982	2.11e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
ICOPOGPD_00983	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
ICOPOGPD_00984	5.71e-305	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
ICOPOGPD_00985	1.1e-177	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
ICOPOGPD_00986	5.79e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICOPOGPD_00987	1.91e-142	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
ICOPOGPD_00988	1.76e-47	M1-755	-	-	P	ko:K09155	-	ko00000	Hemerythrin HHE cation binding domain protein
ICOPOGPD_00989	9.28e-317	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
ICOPOGPD_00990	5.24e-189	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICOPOGPD_00991	5.16e-218	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
ICOPOGPD_00992	1.03e-92	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICOPOGPD_00993	4.17e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
ICOPOGPD_00994	9.36e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
ICOPOGPD_00995	9.53e-317	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
ICOPOGPD_00996	1.34e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
ICOPOGPD_00997	1.33e-200	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
ICOPOGPD_00998	1.24e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
ICOPOGPD_00999	3.05e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICOPOGPD_01000	2.49e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICOPOGPD_01001	1.33e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
ICOPOGPD_01002	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
ICOPOGPD_01003	2.53e-246	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
ICOPOGPD_01004	1.52e-239	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
ICOPOGPD_01005	3.76e-19	-	-	-	-	-	-	-	-
ICOPOGPD_01006	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ICOPOGPD_01007	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
ICOPOGPD_01008	8.62e-228	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
ICOPOGPD_01009	7.45e-48	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICOPOGPD_01010	8.58e-176	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
ICOPOGPD_01011	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01012	4.31e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01013	4.77e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
ICOPOGPD_01014	6.58e-32	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
ICOPOGPD_01015	2.61e-156	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICOPOGPD_01016	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
ICOPOGPD_01017	1.67e-293	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
ICOPOGPD_01018	5.16e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
ICOPOGPD_01019	0.0	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
ICOPOGPD_01020	0.0	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
ICOPOGPD_01021	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
ICOPOGPD_01022	6.88e-276	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICOPOGPD_01023	1.14e-231	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICOPOGPD_01024	4.34e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
ICOPOGPD_01025	1.04e-274	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01026	5.09e-300	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01028	1.54e-218	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated endoribonuclease Cas2
ICOPOGPD_01029	2.88e-220	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICOPOGPD_01030	2.7e-145	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasE
ICOPOGPD_01031	6.33e-175	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasD
ICOPOGPD_01032	2.12e-234	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
ICOPOGPD_01033	1.79e-138	casB	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasB
ICOPOGPD_01034	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	An automated process has identified a potential problem with this gene model
ICOPOGPD_01035	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
ICOPOGPD_01036	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01037	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
ICOPOGPD_01038	8.44e-300	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICOPOGPD_01039	2.71e-152	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICOPOGPD_01040	7.73e-277	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICOPOGPD_01041	3.15e-315	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
ICOPOGPD_01042	8.07e-180	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
ICOPOGPD_01043	8.75e-200	-	-	-	S	-	-	-	Phospholipase, patatin family
ICOPOGPD_01044	9.28e-132	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
ICOPOGPD_01045	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
ICOPOGPD_01046	3.9e-51	-	-	-	S	-	-	-	granule-associated protein
ICOPOGPD_01047	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ICOPOGPD_01048	2.28e-252	XK27_12525	-	-	S	-	-	-	hmm pf01594
ICOPOGPD_01049	7.12e-135	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
ICOPOGPD_01050	2.62e-138	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
ICOPOGPD_01051	1.61e-139	XK27_06100	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
ICOPOGPD_01052	7.14e-189	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICOPOGPD_01053	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01054	1.74e-309	-	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
ICOPOGPD_01055	0.0	-	-	-	M	-	-	-	Polysaccharide biosynthesis protein
ICOPOGPD_01056	5.72e-263	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICOPOGPD_01057	7.07e-220	galnac-T15	-	-	S	ko:K07011	-	ko00000	glycosyl transferase family 2
ICOPOGPD_01058	5.31e-103	-	-	-	-	-	-	-	-
ICOPOGPD_01059	1.19e-258	-	-	-	M	-	-	-	glycosyl transferase group 1
ICOPOGPD_01060	8.51e-210	-	-	-	S	-	-	-	Glycosyl transferase family 2
ICOPOGPD_01061	4.56e-206	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
ICOPOGPD_01062	2.56e-163	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ICOPOGPD_01063	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
ICOPOGPD_01064	1.34e-156	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
ICOPOGPD_01065	5.77e-149	capA	-	-	M	-	-	-	biosynthesis protein
ICOPOGPD_01066	2.13e-171	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
ICOPOGPD_01067	5.95e-305	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
ICOPOGPD_01068	2.28e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
ICOPOGPD_01069	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
ICOPOGPD_01070	1.38e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
ICOPOGPD_01071	2.72e-119	yybC	-	-	-	-	-	-	-
ICOPOGPD_01072	1.6e-111	XK27_03610	-	-	K	-	-	-	Gnat family
ICOPOGPD_01073	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICOPOGPD_01074	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
ICOPOGPD_01075	1.1e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICOPOGPD_01076	3.39e-155	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
ICOPOGPD_01077	3.71e-29	-	-	-	M	-	-	-	LysM domain
ICOPOGPD_01078	1.47e-115	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
ICOPOGPD_01079	5.18e-291	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
ICOPOGPD_01080	0.0	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
ICOPOGPD_01081	3.24e-126	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
ICOPOGPD_01082	2.64e-285	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
ICOPOGPD_01083	3.84e-235	XK27_05220	-	-	S	-	-	-	permease
ICOPOGPD_01084	5.85e-119	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
ICOPOGPD_01085	2.32e-208	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ICOPOGPD_01086	1.04e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
ICOPOGPD_01087	1.08e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICOPOGPD_01088	3.9e-266	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICOPOGPD_01089	1.55e-197	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
ICOPOGPD_01090	5.19e-170	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
ICOPOGPD_01091	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
ICOPOGPD_01092	2.05e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
ICOPOGPD_01093	2.22e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
ICOPOGPD_01094	7.25e-206	XK27_00115	-	-	K	-	-	-	Acetyltransferase GNAT family
ICOPOGPD_01095	3.03e-188	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
ICOPOGPD_01096	5.85e-275	murM	2.3.2.10	-	V	ko:K05363	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
ICOPOGPD_01097	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01098	2.68e-75	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
ICOPOGPD_01099	2.52e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
ICOPOGPD_01100	2.23e-314	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
ICOPOGPD_01101	1.44e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICOPOGPD_01102	1.1e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_01103	2.21e-190	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
ICOPOGPD_01104	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01105	1.75e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
ICOPOGPD_01106	3.01e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
ICOPOGPD_01107	1.43e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
ICOPOGPD_01108	1.02e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICOPOGPD_01110	3.91e-268	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICOPOGPD_01111	0.0	ydaM	-	-	M	-	-	-	Glycosyltransferases, probably involved in cell wall biogenesis
ICOPOGPD_01113	2.99e-176	-	-	-	-	-	-	-	-
ICOPOGPD_01114	3.97e-276	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICOPOGPD_01115	1.7e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01116	8.92e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICOPOGPD_01117	7.11e-225	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICOPOGPD_01118	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICOPOGPD_01119	6.2e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
ICOPOGPD_01120	9.43e-205	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICOPOGPD_01121	5.66e-29	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
ICOPOGPD_01123	5e-165	-	-	-	K	-	-	-	cell adhesion
ICOPOGPD_01124	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01126	2.33e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICOPOGPD_01127	4.09e-272	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter ClC family
ICOPOGPD_01128	3.64e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
ICOPOGPD_01129	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
ICOPOGPD_01130	3.48e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
ICOPOGPD_01131	9.44e-24	XK27_08880	-	-	-	-	-	-	-
ICOPOGPD_01132	3.8e-163	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
ICOPOGPD_01133	3.57e-192	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Esterase
ICOPOGPD_01134	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICOPOGPD_01135	3.8e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01136	1.37e-190	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
ICOPOGPD_01137	8.33e-230	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
ICOPOGPD_01139	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
ICOPOGPD_01140	3.31e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ICOPOGPD_01141	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
ICOPOGPD_01142	1.13e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICOPOGPD_01143	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICOPOGPD_01144	7.84e-241	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ICOPOGPD_01145	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICOPOGPD_01146	1.24e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICOPOGPD_01147	1.44e-228	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
ICOPOGPD_01149	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICOPOGPD_01150	9.58e-126	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_01151	4.73e-208	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
ICOPOGPD_01152	1.68e-191	WQ51_01275	-	-	S	-	-	-	DegV family
ICOPOGPD_01153	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
ICOPOGPD_01154	5.12e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
ICOPOGPD_01155	1.1e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
ICOPOGPD_01156	2.79e-195	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
ICOPOGPD_01157	7.02e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICOPOGPD_01158	4.4e-297	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICOPOGPD_01160	6.16e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICOPOGPD_01161	1.05e-161	dnaD	-	-	-	ko:K02086	-	ko00000	-
ICOPOGPD_01162	2.41e-233	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICOPOGPD_01163	6.18e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICOPOGPD_01164	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
ICOPOGPD_01165	3.47e-85	GnaT	2.5.1.16	-	K	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferase
ICOPOGPD_01166	1.64e-27	-	-	-	Q	-	-	-	Methyltransferase domain
ICOPOGPD_01167	5.59e-173	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
ICOPOGPD_01168	2.57e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICOPOGPD_01169	6.88e-144	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
ICOPOGPD_01170	6.13e-313	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICOPOGPD_01171	2.21e-299	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
ICOPOGPD_01172	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_01173	1.36e-303	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01174	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_01175	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
ICOPOGPD_01176	5.83e-229	-	-	-	M	-	-	-	glycosyl transferase family 2
ICOPOGPD_01177	2.22e-146	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
ICOPOGPD_01178	1.02e-186	-	-	-	P	-	-	-	molecular chaperone
ICOPOGPD_01179	7.63e-132	XK27_05505	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
ICOPOGPD_01182	2.99e-65	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
ICOPOGPD_01183	6.01e-80	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICOPOGPD_01184	5.4e-174	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICOPOGPD_01185	1.38e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICOPOGPD_01186	1.16e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICOPOGPD_01187	3.35e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
ICOPOGPD_01188	8.78e-300	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICOPOGPD_01189	2.93e-151	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ICOPOGPD_01190	1.89e-227	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICOPOGPD_01191	1.13e-247	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICOPOGPD_01192	1.56e-81	XK27_08085	-	-	-	-	-	-	-
ICOPOGPD_01193	1.31e-197	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
ICOPOGPD_01194	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01195	1.5e-177	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
ICOPOGPD_01196	2.41e-149	-	-	-	S	-	-	-	tigr01906
ICOPOGPD_01197	3.01e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICOPOGPD_01198	7.18e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
ICOPOGPD_01199	7.7e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
ICOPOGPD_01202	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01203	3.86e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICOPOGPD_01204	3.91e-142	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
ICOPOGPD_01205	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICOPOGPD_01206	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
ICOPOGPD_01207	1.73e-248	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
ICOPOGPD_01208	1.66e-141	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
ICOPOGPD_01209	9.19e-30	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
ICOPOGPD_01210	3.96e-181	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICOPOGPD_01211	5.39e-153	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
ICOPOGPD_01212	5.03e-84	mesH	-	-	S	-	-	-	GtrA-like protein
ICOPOGPD_01213	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICOPOGPD_01214	3.46e-216	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_01215	4.57e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICOPOGPD_01216	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
ICOPOGPD_01217	3.57e-193	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
ICOPOGPD_01218	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICOPOGPD_01219	2.22e-171	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
ICOPOGPD_01220	7.55e-53	-	-	-	S	-	-	-	yiaA/B two helix domain
ICOPOGPD_01221	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
ICOPOGPD_01222	1.06e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
ICOPOGPD_01223	8.39e-239	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
ICOPOGPD_01224	3.46e-288	XK27_05680	-	-	M	-	-	-	carbamoylphosphate synthase large subunit
ICOPOGPD_01225	4.54e-197	XK27_05675	-	-	S	-	-	-	Esterase
ICOPOGPD_01226	6.48e-207	XK27_05670	-	-	S	ko:K07017	-	ko00000	Putative esterase
ICOPOGPD_01227	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
ICOPOGPD_01228	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICOPOGPD_01229	2.72e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
ICOPOGPD_01230	2.94e-282	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
ICOPOGPD_01231	2.46e-270	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
ICOPOGPD_01232	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICOPOGPD_01233	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
ICOPOGPD_01234	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICOPOGPD_01235	1.29e-235	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICOPOGPD_01236	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICOPOGPD_01237	2.89e-193	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
ICOPOGPD_01238	1.89e-186	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
ICOPOGPD_01239	9.29e-40	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
ICOPOGPD_01240	4.04e-129	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
ICOPOGPD_01241	9.77e-160	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICOPOGPD_01242	1.31e-303	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICOPOGPD_01243	1.23e-308	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICOPOGPD_01244	1.91e-188	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICOPOGPD_01245	1.34e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICOPOGPD_01246	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICOPOGPD_01247	5.19e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
ICOPOGPD_01248	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
ICOPOGPD_01249	3.4e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
ICOPOGPD_01250	1.86e-37	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
ICOPOGPD_01251	9.25e-108	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
ICOPOGPD_01252	5.49e-119	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
ICOPOGPD_01253	3.14e-147	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
ICOPOGPD_01254	5.23e-240	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
ICOPOGPD_01255	1.59e-143	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
ICOPOGPD_01256	1.1e-235	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
ICOPOGPD_01257	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ICOPOGPD_01258	5.6e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
ICOPOGPD_01259	8.61e-97	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
ICOPOGPD_01260	1.05e-166	sitB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_01261	4.06e-171	mtsC	-	-	P	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Mn2 Zn2 transport systems, permease components
ICOPOGPD_01262	1.08e-214	psaA	-	-	P	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
ICOPOGPD_01263	3.04e-148	sirR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
ICOPOGPD_01264	3.3e-187	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
ICOPOGPD_01265	1.04e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
ICOPOGPD_01266	2.52e-238	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
ICOPOGPD_01267	1.3e-301	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01268	0.0	-	-	-	M	-	-	-	Right handed beta helix region
ICOPOGPD_01269	6.18e-206	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
ICOPOGPD_01270	1.05e-253	higA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	Pfam:DUF955
ICOPOGPD_01271	9.64e-68	-	-	-	-	-	-	-	-
ICOPOGPD_01272	5.82e-203	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
ICOPOGPD_01273	7.45e-144	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
ICOPOGPD_01274	1.68e-176	-	-	-	S	-	-	-	Protein conserved in bacteria
ICOPOGPD_01275	1.54e-309	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
ICOPOGPD_01276	0.0	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
ICOPOGPD_01277	0.0	-	-	-	S	-	-	-	SIR2-like domain
ICOPOGPD_01278	5.28e-159	-	-	-	-	ko:K15051	-	ko00000	-
ICOPOGPD_01279	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICOPOGPD_01281	1.17e-167	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
ICOPOGPD_01282	1.96e-275	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
ICOPOGPD_01283	9.86e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICOPOGPD_01284	1.98e-69	hmpP2	-	-	G	-	-	-	hydrolase
ICOPOGPD_01285	9.89e-89	hmpP2	-	-	G	-	-	-	hydrolase
ICOPOGPD_01286	3.49e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
ICOPOGPD_01287	1.34e-193	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
ICOPOGPD_01288	1.23e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICOPOGPD_01289	5.93e-149	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
ICOPOGPD_01290	1.88e-223	-	-	-	S	ko:K07025	-	ko00000	hydrolase
ICOPOGPD_01291	1.22e-36	-	-	-	-	-	-	-	-
ICOPOGPD_01292	2.85e-211	-	-	-	M	-	-	-	LysM domain
ICOPOGPD_01293	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
ICOPOGPD_01295	9.86e-230	dapB	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
ICOPOGPD_01296	2.59e-123	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
ICOPOGPD_01297	0.0	-	-	-	L	-	-	-	helicase
ICOPOGPD_01298	3.55e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
ICOPOGPD_01300	9.35e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
ICOPOGPD_01301	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
ICOPOGPD_01303	7.33e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
ICOPOGPD_01304	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
ICOPOGPD_01305	1.75e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
ICOPOGPD_01307	1.59e-89	ytxH	-	-	S	-	-	-	General stress protein
ICOPOGPD_01308	9.98e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICOPOGPD_01309	2.23e-192	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICOPOGPD_01310	2.87e-218	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICOPOGPD_01311	1.02e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
ICOPOGPD_01312	2.36e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
ICOPOGPD_01313	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
ICOPOGPD_01315	2.79e-200	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
ICOPOGPD_01316	1.97e-190	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
ICOPOGPD_01317	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease and related transporters (MFS superfamily)
ICOPOGPD_01318	1.14e-133	-	-	-	-	-	-	-	-
ICOPOGPD_01319	1.2e-153	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
ICOPOGPD_01320	5.54e-120	-	-	-	S	-	-	-	CAAX protease self-immunity
ICOPOGPD_01321	6.44e-69	-	-	-	-	-	-	-	-
ICOPOGPD_01323	1.74e-85	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
ICOPOGPD_01324	1.13e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
ICOPOGPD_01325	6.28e-30	-	-	-	M	-	-	-	Bacterial lipoprotein
ICOPOGPD_01327	6.56e-64	-	-	-	-	-	-	-	-
ICOPOGPD_01328	6.81e-100	-	-	-	K	-	-	-	TetR family transcriptional regulator
ICOPOGPD_01329	8.43e-107	-	-	-	Q	-	-	-	Methyltransferase domain
ICOPOGPD_01330	4.69e-163	-	-	-	S	-	-	-	Putative esterase
ICOPOGPD_01331	1.05e-230	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
ICOPOGPD_01332	1.32e-169	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
ICOPOGPD_01333	1.7e-209	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICOPOGPD_01334	1.15e-160	-	-	-	V	-	-	-	CAAX protease self-immunity
ICOPOGPD_01335	2.61e-199	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
ICOPOGPD_01336	1.05e-111	tetR	-	-	K	-	-	-	transcriptional regulator
ICOPOGPD_01337	0.0	-	-	-	P	-	-	-	Major facilitator superfamily
ICOPOGPD_01338	3.06e-286	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01339	0.0	-	-	-	M	-	-	-	family 8
ICOPOGPD_01340	5.06e-145	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
ICOPOGPD_01341	1.64e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
ICOPOGPD_01342	3.39e-191	ChZ00x2	-	-	S	-	-	-	EDD domain protein, DegV family
ICOPOGPD_01343	5.91e-261	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	transporter
ICOPOGPD_01344	2.37e-173	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ICOPOGPD_01345	8.78e-206	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
ICOPOGPD_01346	1.43e-178	-	-	-	S	-	-	-	CAAX protease self-immunity
ICOPOGPD_01347	2.21e-177	-	-	-	S	-	-	-	Alpha beta hydrolase
ICOPOGPD_01348	1.1e-85	-	-	-	-	-	-	-	-
ICOPOGPD_01349	2.46e-70	-	-	-	D	-	-	-	Plasmid stabilization system
ICOPOGPD_01350	4.7e-58	-	-	-	-	-	-	-	-
ICOPOGPD_01351	6.4e-189	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ICOPOGPD_01352	1.77e-77	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
ICOPOGPD_01353	1.37e-60	-	-	-	-	-	-	-	-
ICOPOGPD_01354	0.0	-	-	-	O	-	-	-	Molecular chaperone. Has ATPase activity
ICOPOGPD_01355	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICOPOGPD_01356	1.28e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
ICOPOGPD_01357	9.42e-258	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
ICOPOGPD_01358	5.29e-195	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
ICOPOGPD_01359	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_01360	2.42e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
ICOPOGPD_01361	6.28e-111	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICOPOGPD_01362	1.77e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ICOPOGPD_01363	2.67e-222	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
ICOPOGPD_01364	2.99e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
ICOPOGPD_01365	2.24e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
ICOPOGPD_01366	1.29e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICOPOGPD_01367	7.17e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ICOPOGPD_01368	9.52e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICOPOGPD_01369	2.48e-152	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ICOPOGPD_01370	3.99e-278	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
ICOPOGPD_01371	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
ICOPOGPD_01372	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01373	1.1e-34	WQ51_00785	-	-	-	-	-	-	-
ICOPOGPD_01374	2.69e-10	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01375	5.33e-263	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01376	6.13e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICOPOGPD_01377	1.4e-99	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
ICOPOGPD_01378	1.68e-255	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
ICOPOGPD_01379	2.2e-252	XK27_07735	-	-	S	-	-	-	YjbR
ICOPOGPD_01380	1.83e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
ICOPOGPD_01381	2.21e-255	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
ICOPOGPD_01382	1.17e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
ICOPOGPD_01383	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICOPOGPD_01384	1.98e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICOPOGPD_01385	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICOPOGPD_01386	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
ICOPOGPD_01387	1.52e-283	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
ICOPOGPD_01388	5.93e-128	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICOPOGPD_01389	1.97e-191	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICOPOGPD_01390	1.16e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICOPOGPD_01391	2.97e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
ICOPOGPD_01392	1.31e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICOPOGPD_01393	9.74e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
ICOPOGPD_01394	5.31e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICOPOGPD_01395	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
ICOPOGPD_01396	8.33e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICOPOGPD_01397	1.72e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICOPOGPD_01398	1.3e-193	-	-	-	I	-	-	-	Alpha/beta hydrolase family
ICOPOGPD_01399	6.95e-12	-	-	-	-	-	-	-	-
ICOPOGPD_01400	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
ICOPOGPD_01401	1.49e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
ICOPOGPD_01402	8.98e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_01403	2.2e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
ICOPOGPD_01404	3.31e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
ICOPOGPD_01405	1.51e-233	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICOPOGPD_01406	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
ICOPOGPD_01407	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
ICOPOGPD_01408	2.23e-65	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
ICOPOGPD_01409	1.38e-226	-	-	-	S	-	-	-	oxidoreductase
ICOPOGPD_01410	1.6e-149	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
ICOPOGPD_01411	5.27e-140	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
ICOPOGPD_01414	0.0	-	-	-	L	-	-	-	Recombinase
ICOPOGPD_01416	4.58e-178	-	-	-	S	-	-	-	Replication-relaxation
ICOPOGPD_01417	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
ICOPOGPD_01420	1.7e-27	-	-	-	-	-	-	-	-
ICOPOGPD_01423	1.72e-133	-	-	-	L	-	-	-	recombinase activity
ICOPOGPD_01426	9.51e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
ICOPOGPD_01429	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
ICOPOGPD_01430	1.75e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
ICOPOGPD_01431	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICOPOGPD_01434	1.14e-162	-	-	-	-	-	-	-	-
ICOPOGPD_01435	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICOPOGPD_01436	1.09e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICOPOGPD_01437	4.35e-19	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
ICOPOGPD_01438	3.14e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
ICOPOGPD_01439	4.42e-221	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
ICOPOGPD_01440	0.0	lysP	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
ICOPOGPD_01441	9.58e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
ICOPOGPD_01442	8.89e-288	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICOPOGPD_01443	2.97e-30	-	-	-	-	-	-	-	-
ICOPOGPD_01444	3.16e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICOPOGPD_01445	4.23e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICOPOGPD_01446	4.24e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
ICOPOGPD_01447	2.86e-287	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
ICOPOGPD_01448	4.38e-102	-	-	-	K	-	-	-	hmm pf08876
ICOPOGPD_01449	3.52e-152	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
ICOPOGPD_01450	1.64e-39	pspC	-	-	KT	-	-	-	PspC domain protein
ICOPOGPD_01451	9.01e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
ICOPOGPD_01452	1.4e-205	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ICOPOGPD_01453	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICOPOGPD_01455	9.45e-317	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ICOPOGPD_01456	1.41e-241	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
ICOPOGPD_01457	2.69e-10	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01458	1.67e-266	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01459	0.0	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
ICOPOGPD_01460	1.8e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICOPOGPD_01461	1.08e-43	-	-	-	-	-	-	-	-
ICOPOGPD_01462	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
ICOPOGPD_01463	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICOPOGPD_01464	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
ICOPOGPD_01465	2.51e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICOPOGPD_01466	3.25e-210	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
ICOPOGPD_01467	1.04e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
ICOPOGPD_01468	7.02e-190	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
ICOPOGPD_01469	1.81e-133	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
ICOPOGPD_01470	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01471	2.94e-315	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICOPOGPD_01472	1.17e-175	-	-	-	E	-	-	-	Alpha beta hydrolase
ICOPOGPD_01474	9e-255	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
ICOPOGPD_01475	3.04e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
ICOPOGPD_01476	1.06e-183	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
ICOPOGPD_01477	1.87e-148	-	-	-	S	-	-	-	VIT family
ICOPOGPD_01478	6.04e-173	-	-	-	F	-	-	-	Phosphorylase superfamily
ICOPOGPD_01480	3.25e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
ICOPOGPD_01481	5.58e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
ICOPOGPD_01482	3.26e-161	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICOPOGPD_01483	1.61e-250	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICOPOGPD_01484	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01485	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01486	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
ICOPOGPD_01488	6.49e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICOPOGPD_01489	1.7e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICOPOGPD_01490	5.35e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
ICOPOGPD_01491	5.6e-158	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_01492	1.21e-246	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICOPOGPD_01493	9.28e-170	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
ICOPOGPD_01494	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
ICOPOGPD_01495	7.9e-270	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
ICOPOGPD_01496	1.6e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
ICOPOGPD_01497	5.76e-281	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
ICOPOGPD_01498	1.45e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICOPOGPD_01499	2.52e-208	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
ICOPOGPD_01500	9.44e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICOPOGPD_01501	2.86e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
ICOPOGPD_01503	3.11e-89	-	-	-	K	-	-	-	Helix-turn-helix
ICOPOGPD_01506	3.16e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICOPOGPD_01507	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01508	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_01510	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
ICOPOGPD_01511	7.03e-53	ynzC	-	-	S	-	-	-	UPF0291 protein
ICOPOGPD_01512	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
ICOPOGPD_01513	1.23e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
ICOPOGPD_01514	2.93e-280	-	-	-	S	-	-	-	membrane
ICOPOGPD_01515	4.73e-269	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICOPOGPD_01516	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
ICOPOGPD_01517	1.97e-157	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
ICOPOGPD_01518	4.44e-111	-	-	-	S	-	-	-	Bacterial inner membrane protein
ICOPOGPD_01519	3.76e-189	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
ICOPOGPD_01520	1.92e-140	-	-	-	S	ko:K07023	-	ko00000	HD domain
ICOPOGPD_01521	1.32e-139	mur1	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
ICOPOGPD_01522	1.86e-70	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
ICOPOGPD_01523	6.07e-292	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
ICOPOGPD_01524	2.6e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICOPOGPD_01525	2e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
ICOPOGPD_01526	8.2e-177	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
ICOPOGPD_01527	2.15e-204	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
ICOPOGPD_01528	1.45e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICOPOGPD_01530	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICOPOGPD_01531	3.13e-173	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICOPOGPD_01532	3.2e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICOPOGPD_01533	3.93e-275	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
ICOPOGPD_01534	5.52e-303	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01535	1.24e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
ICOPOGPD_01536	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICOPOGPD_01537	3.17e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICOPOGPD_01538	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICOPOGPD_01539	8.62e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICOPOGPD_01540	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICOPOGPD_01541	3e-158	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
ICOPOGPD_01542	1.69e-22	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICOPOGPD_01543	5.56e-254	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
ICOPOGPD_01545	5.68e-76	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
ICOPOGPD_01546	2.69e-92	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
ICOPOGPD_01547	1.84e-281	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICOPOGPD_01548	2.79e-136	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
ICOPOGPD_01549	2.43e-265	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICOPOGPD_01550	3.85e-206	-	-	-	GK	-	-	-	ROK family
ICOPOGPD_01551	4.77e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
ICOPOGPD_01552	4.79e-196	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
ICOPOGPD_01553	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01554	7.79e-262	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
ICOPOGPD_01555	3.07e-167	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
ICOPOGPD_01556	4.03e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
ICOPOGPD_01557	9.28e-271	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ICOPOGPD_01558	3.23e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
ICOPOGPD_01559	4.44e-104	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICOPOGPD_01560	4.82e-78	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICOPOGPD_01561	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
ICOPOGPD_01562	1.75e-186	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICOPOGPD_01563	4.02e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
ICOPOGPD_01564	0.0	ydaO	-	-	E	-	-	-	amino acid
ICOPOGPD_01565	1.85e-297	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
ICOPOGPD_01566	3.71e-49	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
ICOPOGPD_01567	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
ICOPOGPD_01569	5.9e-255	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
ICOPOGPD_01570	1.88e-166	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
ICOPOGPD_01571	1.02e-250	-	-	-	O	-	-	-	protein import
ICOPOGPD_01572	1.94e-212	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
ICOPOGPD_01573	3.71e-15	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
ICOPOGPD_01574	4.12e-254	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICOPOGPD_01576	1.41e-201	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
ICOPOGPD_01577	1.36e-94	-	-	-	S	-	-	-	QueT transporter
ICOPOGPD_01579	2.78e-226	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
ICOPOGPD_01580	5.49e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ICOPOGPD_01581	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICOPOGPD_01582	1.71e-111	ccl	-	-	S	-	-	-	cog cog4708
ICOPOGPD_01583	1.64e-210	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
ICOPOGPD_01584	4.94e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
ICOPOGPD_01585	7.45e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
ICOPOGPD_01586	1.44e-127	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
ICOPOGPD_01587	1.34e-295	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICOPOGPD_01588	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
ICOPOGPD_01589	2.22e-140	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
ICOPOGPD_01590	1.24e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
ICOPOGPD_01591	1.87e-221	nodB3	-	-	G	-	-	-	deacetylase
ICOPOGPD_01592	1.5e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
ICOPOGPD_01593	3.52e-57	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
ICOPOGPD_01594	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICOPOGPD_01595	3.84e-203	corA	-	-	P	-	-	-	CorA-like protein
ICOPOGPD_01596	1.51e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
ICOPOGPD_01597	5.34e-128	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
ICOPOGPD_01598	1.58e-204	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
ICOPOGPD_01599	1.28e-220	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
ICOPOGPD_01600	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICOPOGPD_01601	2.04e-149	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
ICOPOGPD_01602	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICOPOGPD_01603	3.06e-214	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
ICOPOGPD_01604	3.62e-145	-	-	-	L	-	-	-	Helix-turn-helix domain
ICOPOGPD_01605	1.1e-198	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
ICOPOGPD_01606	1.27e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_01607	1.87e-147	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01608	2.46e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01609	8.85e-244	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
ICOPOGPD_01610	2.72e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
ICOPOGPD_01611	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
ICOPOGPD_01612	6.08e-97	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
ICOPOGPD_01615	7.14e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ICOPOGPD_01616	1.22e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ICOPOGPD_01617	3.59e-127	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
ICOPOGPD_01618	9.27e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
ICOPOGPD_01619	1.74e-227	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICOPOGPD_01620	7.09e-136	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
ICOPOGPD_01621	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICOPOGPD_01622	2.52e-54	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
ICOPOGPD_01623	1.19e-152	XK27_10210	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
ICOPOGPD_01624	0.0	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
ICOPOGPD_01625	7.46e-29	-	-	-	S	-	-	-	Bacteriocin (Lactococcin_972)
ICOPOGPD_01626	2.28e-77	-	-	-	-	-	-	-	-
ICOPOGPD_01627	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
ICOPOGPD_01628	5.38e-55	-	-	-	-	-	-	-	-
ICOPOGPD_01629	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICOPOGPD_01631	2.75e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01632	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01633	5.52e-303	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01634	2.71e-156	-	-	-	K	-	-	-	transcriptional regulator, MerR family
ICOPOGPD_01635	2.26e-136	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
ICOPOGPD_01636	5.18e-76	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
ICOPOGPD_01637	3.13e-83	XK27_02560	-	-	S	-	-	-	cog cog2151
ICOPOGPD_01638	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
ICOPOGPD_01639	7.24e-284	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
ICOPOGPD_01641	8.79e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICOPOGPD_01642	2.95e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
ICOPOGPD_01643	5.17e-224	XK27_05910	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
ICOPOGPD_01644	1.01e-169	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01645	3.56e-94	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
ICOPOGPD_01648	2.41e-134	-	-	-	-	-	-	-	-
ICOPOGPD_01650	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
ICOPOGPD_01651	3.61e-59	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	Addiction module toxin, Txe YoeB family
ICOPOGPD_01652	6.54e-53	yefM	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
ICOPOGPD_01653	4.87e-260	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
ICOPOGPD_01654	3.69e-178	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
ICOPOGPD_01655	6.9e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICOPOGPD_01656	2.86e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
ICOPOGPD_01657	6.44e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICOPOGPD_01658	4.57e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
ICOPOGPD_01659	9.31e-274	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
ICOPOGPD_01660	4.52e-128	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
ICOPOGPD_01661	5.59e-198	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ICOPOGPD_01662	4.86e-84	-	-	-	-	-	-	-	-
ICOPOGPD_01663	2.47e-280	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICOPOGPD_01664	1.19e-74	-	-	-	-	-	-	-	-
ICOPOGPD_01665	4.76e-53	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
ICOPOGPD_01666	0.0	celR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
ICOPOGPD_01667	4.78e-62	celB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
ICOPOGPD_01668	1.09e-42	-	-	-	S	ko:K15383	-	ko00000,ko02000	PQ loop repeat
ICOPOGPD_01669	0.0	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ICOPOGPD_01671	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICOPOGPD_01672	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICOPOGPD_01673	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICOPOGPD_01674	7.07e-81	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICOPOGPD_01675	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
ICOPOGPD_01676	1.54e-111	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
ICOPOGPD_01677	7.41e-184	-	-	-	K	-	-	-	WYL domain
ICOPOGPD_01678	6.09e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
ICOPOGPD_01679	2.12e-180	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ICOPOGPD_01680	6.15e-302	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
ICOPOGPD_01681	6.2e-98	XK27_03180	-	-	T	-	-	-	universal stress protein
ICOPOGPD_01683	4.91e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICOPOGPD_01685	1.36e-302	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
ICOPOGPD_01686	2.79e-180	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_01688	7.29e-32	-	-	-	-	-	-	-	-
ICOPOGPD_01689	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
ICOPOGPD_01691	6.82e-122	mraW1	-	-	J	-	-	-	(SAM)-dependent
ICOPOGPD_01692	3.42e-233	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
ICOPOGPD_01693	1.84e-241	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
ICOPOGPD_01694	3.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICOPOGPD_01695	2.12e-119	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
ICOPOGPD_01696	1.13e-218	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICOPOGPD_01697	3.64e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
ICOPOGPD_01698	2.55e-165	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
ICOPOGPD_01699	7.25e-208	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01700	1.15e-196	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
ICOPOGPD_01702	3.72e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICOPOGPD_01703	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
ICOPOGPD_01705	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
ICOPOGPD_01706	1.4e-189	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
ICOPOGPD_01707	2.81e-99	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICOPOGPD_01709	1.66e-220	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
ICOPOGPD_01710	5.62e-181	cppA	-	-	E	-	-	-	CppA N-terminal
ICOPOGPD_01711	6.72e-126	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ICOPOGPD_01712	7.88e-210	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
ICOPOGPD_01713	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICOPOGPD_01714	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01715	2.32e-245	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01718	3.48e-59	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
ICOPOGPD_01720	2.39e-174	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
ICOPOGPD_01721	8.13e-300	comD	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
ICOPOGPD_01726	4.4e-34	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
ICOPOGPD_01727	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01728	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01730	9.07e-119	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
ICOPOGPD_01731	7.84e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ICOPOGPD_01732	3.22e-107	yutD	-	-	J	-	-	-	protein conserved in bacteria
ICOPOGPD_01733	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
ICOPOGPD_01736	4.56e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICOPOGPD_01737	1.99e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICOPOGPD_01738	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
ICOPOGPD_01739	5.32e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
ICOPOGPD_01740	1.54e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICOPOGPD_01741	4.35e-37	-	-	-	-	-	-	-	-
ICOPOGPD_01744	1.79e-77	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
ICOPOGPD_01745	3.81e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
ICOPOGPD_01746	8.23e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICOPOGPD_01747	2.89e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICOPOGPD_01748	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
ICOPOGPD_01749	8.31e-169	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
ICOPOGPD_01750	6.02e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
ICOPOGPD_01751	8.18e-305	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01752	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
ICOPOGPD_01753	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ICOPOGPD_01754	1.3e-301	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01755	2.14e-313	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01756	3.65e-308	dcuS	2.7.13.3	-	T	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01757	6.4e-15	-	-	-	-	-	-	-	-
ICOPOGPD_01760	1.39e-185	-	-	-	V	ko:K21397	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
ICOPOGPD_01762	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
ICOPOGPD_01763	3.11e-247	mccF	-	-	V	-	-	-	LD-carboxypeptidase
ICOPOGPD_01764	1.06e-57	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
ICOPOGPD_01765	5.61e-97	mccF	-	-	V	-	-	-	LD-carboxypeptidase
ICOPOGPD_01766	2.37e-153	-	-	-	S	-	-	-	membrane
ICOPOGPD_01767	2.17e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
ICOPOGPD_01768	0.0	-	-	-	KT	-	-	-	response to antibiotic
ICOPOGPD_01769	3.18e-171	yebC	-	-	M	-	-	-	Membrane
ICOPOGPD_01770	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
ICOPOGPD_01771	8.94e-219	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
ICOPOGPD_01773	1.66e-42	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
ICOPOGPD_01777	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICOPOGPD_01778	1.64e-244	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICOPOGPD_01779	4.16e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICOPOGPD_01780	3.67e-247	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICOPOGPD_01781	3.37e-250	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICOPOGPD_01782	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICOPOGPD_01784	4.36e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
ICOPOGPD_01785	2.37e-220	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
ICOPOGPD_01786	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_01787	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
ICOPOGPD_01788	3.14e-228	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	Transcriptional regulator
ICOPOGPD_01789	1.09e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICOPOGPD_01790	7.41e-80	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
ICOPOGPD_01791	8.59e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICOPOGPD_01792	3.59e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
ICOPOGPD_01793	1.14e-253	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
ICOPOGPD_01795	8.63e-186	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
ICOPOGPD_01796	2.65e-38	blpT	-	-	-	-	-	-	-
ICOPOGPD_01799	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_01801	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICOPOGPD_01802	2.19e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
ICOPOGPD_01803	8.39e-159	XK27_01040	-	-	S	-	-	-	Protein of unknown function (DUF1129)
ICOPOGPD_01805	4.1e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICOPOGPD_01806	8.44e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICOPOGPD_01807	6.54e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
ICOPOGPD_01809	1.86e-290	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
ICOPOGPD_01811	4.59e-49	-	-	-	-	-	-	-	-
ICOPOGPD_01813	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICOPOGPD_01814	1.47e-120	-	-	-	K	ko:K14989	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
ICOPOGPD_01815	0.0	-	-	-	T	ko:K14988	ko02020,map02020	ko00000,ko00001,ko00002,ko01001,ko02022	Histidine kinase
ICOPOGPD_01816	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01818	7.57e-301	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
ICOPOGPD_01819	8.61e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
ICOPOGPD_01820	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICOPOGPD_01821	8.59e-115	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
ICOPOGPD_01822	7.01e-36	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ICOPOGPD_01823	2.52e-197	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICOPOGPD_01824	6.48e-136	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
ICOPOGPD_01825	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICOPOGPD_01826	7.72e-61	-	-	-	S	-	-	-	branched-chain amino acid
ICOPOGPD_01827	4.18e-147	XK27_12120	-	-	E	-	-	-	AzlC protein
ICOPOGPD_01828	1.83e-235	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICOPOGPD_01829	4.95e-93	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ICOPOGPD_01830	1.73e-148	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
ICOPOGPD_01831	4.54e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
ICOPOGPD_01832	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICOPOGPD_01833	4.35e-150	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
ICOPOGPD_01834	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
ICOPOGPD_01835	4e-82	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
ICOPOGPD_01836	4.38e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
ICOPOGPD_01837	3.32e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
ICOPOGPD_01839	4.73e-304	-	-	-	L	-	-	-	Transposase
ICOPOGPD_01840	1.41e-239	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICOPOGPD_01841	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICOPOGPD_01842	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICOPOGPD_01843	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICOPOGPD_01844	7.91e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
ICOPOGPD_01845	1.69e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
ICOPOGPD_01846	9.85e-231	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
ICOPOGPD_01847	1.35e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
ICOPOGPD_01848	2.31e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
ICOPOGPD_01849	7.88e-211	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICOPOGPD_01851	7.46e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICOPOGPD_01852	2.2e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICOPOGPD_01853	1.16e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
ICOPOGPD_01854	7.39e-98	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
ICOPOGPD_01855	3.11e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
ICOPOGPD_01856	4.31e-184	-	-	-	S	-	-	-	Macro domain protein
ICOPOGPD_01857	3.68e-77	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
ICOPOGPD_01858	9.65e-67	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
ICOPOGPD_01861	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICOPOGPD_01862	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
ICOPOGPD_01863	1.09e-134	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
ICOPOGPD_01864	1.62e-136	-	-	-	K	-	-	-	Transcriptional regulator
ICOPOGPD_01865	1.02e-237	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
ICOPOGPD_01866	2.98e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICOPOGPD_01867	9.69e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICOPOGPD_01868	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
ICOPOGPD_01869	8.63e-295	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICOPOGPD_01870	1.25e-196	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01871	8.39e-71	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
ICOPOGPD_01872	2.2e-84	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
ICOPOGPD_01873	9.38e-312	fasC	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01874	1.43e-265	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01875	3.55e-201	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
ICOPOGPD_01876	1.44e-293	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
ICOPOGPD_01877	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICOPOGPD_01878	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
ICOPOGPD_01879	1.37e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICOPOGPD_01880	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICOPOGPD_01881	4.66e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
ICOPOGPD_01882	4.77e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
ICOPOGPD_01883	3.55e-164	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
ICOPOGPD_01884	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICOPOGPD_01885	8.52e-96	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
ICOPOGPD_01886	7.02e-103	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
ICOPOGPD_01887	3.33e-140	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
ICOPOGPD_01888	7.29e-307	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
ICOPOGPD_01889	4.28e-181	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
ICOPOGPD_01890	1.37e-123	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
ICOPOGPD_01891	2.08e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
ICOPOGPD_01892	9.64e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
ICOPOGPD_01893	2.2e-150	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
ICOPOGPD_01894	4.68e-121	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICOPOGPD_01895	7.74e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICOPOGPD_01896	5.89e-107	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICOPOGPD_01897	9.74e-176	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
ICOPOGPD_01898	2.93e-196	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
ICOPOGPD_01902	2.23e-113	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICOPOGPD_01903	4.45e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICOPOGPD_01904	3.2e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
ICOPOGPD_01905	1.92e-240	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
ICOPOGPD_01906	2.62e-145	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICOPOGPD_01908	5.78e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
ICOPOGPD_01910	1.51e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
ICOPOGPD_01911	2.36e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICOPOGPD_01912	5.02e-129	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
ICOPOGPD_01914	3.1e-138	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
ICOPOGPD_01915	1.05e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
ICOPOGPD_01916	8.13e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICOPOGPD_01917	6.84e-226	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
ICOPOGPD_01918	3.67e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
ICOPOGPD_01919	9.27e-93	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
ICOPOGPD_01920	1.23e-21	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
ICOPOGPD_01921	9.78e-92	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
ICOPOGPD_01922	1.1e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
ICOPOGPD_01923	1.83e-179	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICOPOGPD_01924	3.65e-223	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICOPOGPD_01925	1.37e-91	-	-	-	S	-	-	-	cog cog4699
ICOPOGPD_01926	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOPOGPD_01927	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOPOGPD_01928	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
ICOPOGPD_01929	5.76e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICOPOGPD_01930	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01931	2.99e-247	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICOPOGPD_01932	4.11e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
ICOPOGPD_01933	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
ICOPOGPD_01934	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
ICOPOGPD_01935	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
ICOPOGPD_01936	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
ICOPOGPD_01937	8.15e-285	norN	-	-	V	-	-	-	Mate efflux family protein
ICOPOGPD_01938	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
ICOPOGPD_01939	6.92e-05	yebC	-	-	M	-	-	-	Membrane
ICOPOGPD_01941	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
ICOPOGPD_01942	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
ICOPOGPD_01943	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
ICOPOGPD_01944	0.0	treP	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_01945	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01947	3.92e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
ICOPOGPD_01948	1.74e-162	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
ICOPOGPD_01949	4.88e-247	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01950	4.93e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
ICOPOGPD_01951	1.34e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
ICOPOGPD_01953	1.37e-305	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
ICOPOGPD_01954	3.03e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
ICOPOGPD_01955	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICOPOGPD_01956	1.63e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICOPOGPD_01957	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICOPOGPD_01958	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
ICOPOGPD_01959	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICOPOGPD_01960	4.85e-151	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICOPOGPD_01961	8.65e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICOPOGPD_01962	1.4e-83	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
ICOPOGPD_01963	9.89e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
ICOPOGPD_01964	7e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICOPOGPD_01965	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICOPOGPD_01966	5.88e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICOPOGPD_01967	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICOPOGPD_01968	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICOPOGPD_01969	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICOPOGPD_01970	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICOPOGPD_01971	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICOPOGPD_01972	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICOPOGPD_01973	6.2e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
ICOPOGPD_01974	4.35e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICOPOGPD_01975	9.44e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICOPOGPD_01976	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICOPOGPD_01977	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICOPOGPD_01978	5.06e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICOPOGPD_01979	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICOPOGPD_01980	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
ICOPOGPD_01981	3.17e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICOPOGPD_01982	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
ICOPOGPD_01983	7.25e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICOPOGPD_01984	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
ICOPOGPD_01985	4.22e-48	-	-	-	S	-	-	-	MORN repeat protein
ICOPOGPD_01986	6.07e-102	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICOPOGPD_01987	3.87e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICOPOGPD_01988	2.54e-120	flaR	-	-	F	-	-	-	topology modulation protein
ICOPOGPD_01989	7.26e-205	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
ICOPOGPD_01990	8.46e-220	-	-	-	S	-	-	-	membrane
ICOPOGPD_01991	4.54e-116	-	-	-	K	-	-	-	sequence-specific DNA binding
ICOPOGPD_01992	2.66e-206	-	-	-	L	-	-	-	Replication initiation factor
ICOPOGPD_01993	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
ICOPOGPD_01994	2.49e-277	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ICOPOGPD_01996	9.84e-299	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
ICOPOGPD_01997	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
ICOPOGPD_01998	9.75e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
ICOPOGPD_01999	9.82e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICOPOGPD_02000	1.34e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
ICOPOGPD_02001	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
ICOPOGPD_02002	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
ICOPOGPD_02003	7.68e-20	-	-	-	-	-	-	-	-
ICOPOGPD_02004	8.53e-115	-	-	-	K	-	-	-	acetyltransferase
ICOPOGPD_02005	3.61e-149	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICOPOGPD_02006	2.66e-155	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
ICOPOGPD_02007	2.53e-214	XK27_01785	-	-	S	-	-	-	cog cog1284
ICOPOGPD_02008	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICOPOGPD_02010	2.6e-296	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
ICOPOGPD_02011	7.97e-182	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_02012	1.68e-59	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
ICOPOGPD_02013	0.000652	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
ICOPOGPD_02014	6.09e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
ICOPOGPD_02015	8.74e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
ICOPOGPD_02016	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
ICOPOGPD_02018	1.62e-139	-	-	-	-	-	-	-	-
ICOPOGPD_02019	1.65e-99	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
ICOPOGPD_02020	6.13e-278	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
ICOPOGPD_02021	6.19e-62	-	-	-	K	-	-	-	nucleotide-binding Protein
ICOPOGPD_02022	2.48e-145	-	-	-	-	-	-	-	-
ICOPOGPD_02024	5.11e-58	-	-	-	-	-	-	-	-
ICOPOGPD_02025	1.55e-235	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ICOPOGPD_02027	9.8e-135	-	-	-	S	-	-	-	Plasmid replication protein
ICOPOGPD_02028	1.33e-29	-	-	-	S	-	-	-	MerR HTH family regulatory protein
ICOPOGPD_02029	6.57e-276	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
ICOPOGPD_02032	0.0	-	-	-	L	-	-	-	Transposase
ICOPOGPD_02033	1.53e-146	XK27_06885	-	-	L	-	-	-	hydrolase
ICOPOGPD_02034	2.93e-67	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
ICOPOGPD_02035	1.8e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
ICOPOGPD_02036	2.18e-146	-	-	-	S	-	-	-	Putative adhesin
ICOPOGPD_02037	1.22e-260	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
ICOPOGPD_02038	1.69e-125	XK27_06935	-	-	K	-	-	-	transcriptional regulator
ICOPOGPD_02039	6.55e-72	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
ICOPOGPD_02040	5.32e-13	-	-	-	-	-	-	-	-
ICOPOGPD_02041	1.25e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICOPOGPD_02042	6.16e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
ICOPOGPD_02043	1.35e-314	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
ICOPOGPD_02044	1.77e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
ICOPOGPD_02045	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
ICOPOGPD_02046	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICOPOGPD_02047	6.35e-131	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
ICOPOGPD_02048	5.42e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICOPOGPD_02049	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
ICOPOGPD_02050	2.43e-121	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
ICOPOGPD_02051	7.81e-106	lytE	-	-	M	-	-	-	LysM domain protein
ICOPOGPD_02052	2.52e-169	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOPOGPD_02053	2.71e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOPOGPD_02054	1.57e-194	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICOPOGPD_02055	2.68e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICOPOGPD_02056	5.42e-172	-	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
ICOPOGPD_02057	2.1e-306	ymfH	-	-	S	-	-	-	Peptidase M16
ICOPOGPD_02058	3.18e-301	albE	-	-	S	-	-	-	Peptidase M16
ICOPOGPD_02059	1.3e-78	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
ICOPOGPD_02060	2.62e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICOPOGPD_02061	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ICOPOGPD_02062	1.93e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
ICOPOGPD_02063	1.27e-191	XK27_10395	-	-	S	-	-	-	membrane
ICOPOGPD_02064	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
ICOPOGPD_02065	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
ICOPOGPD_02066	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
ICOPOGPD_02070	9.43e-155	yoaK	-	-	S	-	-	-	Protein of unknown function (DUF1275)
ICOPOGPD_02071	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICOPOGPD_02072	1.23e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
ICOPOGPD_02073	1.18e-174	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family