ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KNEBHBDB_00001 4.09e-255 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KNEBHBDB_00002 1.23e-54 amd - - E - - - COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KNEBHBDB_00004 1.06e-92 - - - L - - - Transposase
KNEBHBDB_00006 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KNEBHBDB_00010 4.45e-41 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KNEBHBDB_00011 1.55e-162 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KNEBHBDB_00012 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KNEBHBDB_00013 1.68e-55 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KNEBHBDB_00014 6.8e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
KNEBHBDB_00015 2.62e-34 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00016 1.32e-230 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00017 3.95e-56 nodB3 - - G - - - polysaccharide deacetylase
KNEBHBDB_00018 9.73e-115 nodB3 - - G - - - polysaccharide deacetylase
KNEBHBDB_00019 1.76e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KNEBHBDB_00020 1.31e-155 - - - L - - - Transposase
KNEBHBDB_00021 1.53e-212 - - - L ko:K07497 - ko00000 integrase core domain
KNEBHBDB_00023 3.68e-172 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
KNEBHBDB_00024 1.03e-301 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KNEBHBDB_00026 1.69e-106 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
KNEBHBDB_00027 6.86e-166 mesE - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 Transport protein ComB
KNEBHBDB_00028 0.0 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNEBHBDB_00029 9.12e-40 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNEBHBDB_00031 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_00032 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_00035 1.34e-120 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
KNEBHBDB_00036 1.14e-45 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KNEBHBDB_00037 1.44e-14 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KNEBHBDB_00038 3.69e-134 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KNEBHBDB_00039 4.55e-128 yutD - - J - - - protein conserved in bacteria
KNEBHBDB_00040 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_00042 5.56e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KNEBHBDB_00043 3.29e-235 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNEBHBDB_00044 1.06e-129 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_00045 9.62e-72 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_00046 1.24e-181 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_00047 3.89e-62 ftsL - - D - - - cell division protein FtsL
KNEBHBDB_00048 5.76e-245 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KNEBHBDB_00049 6.59e-38 - - - - - - - -
KNEBHBDB_00050 2.72e-47 - - - - - - - -
KNEBHBDB_00051 1.38e-85 - - - - - - - -
KNEBHBDB_00054 8.64e-40 - - - J - - - Protein of unknown function (DUF805)
KNEBHBDB_00055 3.23e-29 - - - D - - - nuclear chromosome segregation
KNEBHBDB_00056 4.08e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNEBHBDB_00057 2.47e-182 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNEBHBDB_00058 2.29e-168 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
KNEBHBDB_00059 1.14e-171 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
KNEBHBDB_00060 3.95e-167 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_00061 4.1e-132 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KNEBHBDB_00062 2.63e-13 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KNEBHBDB_00063 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KNEBHBDB_00064 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KNEBHBDB_00065 1.97e-266 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KNEBHBDB_00066 4.4e-39 - - - S - - - membrane
KNEBHBDB_00067 2.54e-84 - - - S - - - membrane
KNEBHBDB_00068 3.34e-14 XK27_02470 - - K - - - LytTr DNA-binding domain protein
KNEBHBDB_00069 7.41e-82 - - - KT - - - response to antibiotic
KNEBHBDB_00070 7.24e-23 - - - KT - - - response to antibiotic
KNEBHBDB_00071 1.03e-55 yebC - - M - - - Membrane
KNEBHBDB_00072 3.02e-27 yebC - - M - - - Membrane
KNEBHBDB_00073 1.27e-24 yebC - - M - - - Membrane
KNEBHBDB_00074 6.52e-288 - - - S - - - hydrolases of the HAD superfamily
KNEBHBDB_00076 3.11e-95 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00077 1.04e-246 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KNEBHBDB_00078 2.17e-52 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_00079 9.51e-202 tra981A - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
KNEBHBDB_00080 8.55e-150 - - - K - - - Cell envelope-related transcriptional attenuator domain
KNEBHBDB_00081 5.25e-188 - - - G - - - Phosphodiester glycosidase
KNEBHBDB_00083 2.43e-98 - - - S - - - Polysaccharide biosynthesis protein
KNEBHBDB_00084 8.32e-63 - - - S - - - Polysaccharide biosynthesis protein
KNEBHBDB_00085 3.21e-26 - - - S - - - Polysaccharide biosynthesis protein
KNEBHBDB_00087 0.000555 - - - S - - - Glycosyl transferase family 2
KNEBHBDB_00089 8.84e-101 - - - M - - - Glycosyl transferase, family 2
KNEBHBDB_00090 4.66e-29 - - - M - - - Glycosyltransferase WbsX
KNEBHBDB_00091 8.81e-26 - - - - - - - -
KNEBHBDB_00092 7.27e-75 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
KNEBHBDB_00093 7.37e-08 rfbF - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase family 2
KNEBHBDB_00094 1.67e-37 - - - M - - - PFAM Glycosyl transferase, group 1
KNEBHBDB_00095 1.24e-166 - - - M - - - PFAM Glycosyl transferase, group 1
KNEBHBDB_00096 5.18e-106 - - - M - - - Glycosyl transferase 4-like
KNEBHBDB_00097 1.03e-70 - - - M - - - Bacterial sugar transferase
KNEBHBDB_00098 4.85e-152 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
KNEBHBDB_00099 3.04e-140 capA - - M - - - biosynthesis protein
KNEBHBDB_00100 2.12e-141 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
KNEBHBDB_00101 0.0 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KNEBHBDB_00102 1.89e-166 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
KNEBHBDB_00104 1.76e-99 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
KNEBHBDB_00105 1.45e-12 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
KNEBHBDB_00106 4.38e-43 clcA2 - - P - - - chloride
KNEBHBDB_00107 6.72e-61 clcA_2 - - P ko:K03281 - ko00000 chloride channel
KNEBHBDB_00108 5.05e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KNEBHBDB_00109 6.5e-61 - - - S - - - Protein of unknown function (DUF1697)
KNEBHBDB_00110 4.59e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KNEBHBDB_00111 3.16e-64 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNEBHBDB_00112 1.52e-34 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNEBHBDB_00113 1.1e-16 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KNEBHBDB_00114 2.05e-06 - - - V - - - Glucan-binding protein C
KNEBHBDB_00115 3.78e-149 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
KNEBHBDB_00116 4.74e-42 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
KNEBHBDB_00117 1.8e-308 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00118 6.4e-230 - - - EGP - - - Transmembrane secretion effector
KNEBHBDB_00119 4.3e-114 - - - M - - - ATP-grasp domain
KNEBHBDB_00120 1.84e-130 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNEBHBDB_00123 2.44e-13 murA2 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNEBHBDB_00124 1.16e-131 - - - L - - - nUDIX hydrolase
KNEBHBDB_00125 2.11e-221 - 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNEBHBDB_00126 5.14e-200 - - - K ko:K20374 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
KNEBHBDB_00127 1.16e-304 - - - L - - - Transposase
KNEBHBDB_00128 7.72e-89 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 GBS Bsp-like repeat
KNEBHBDB_00130 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KNEBHBDB_00131 6.08e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNEBHBDB_00132 6.77e-209 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KNEBHBDB_00133 1.07e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KNEBHBDB_00134 1.59e-42 - - - P - - - membrane protein (DUF2207)
KNEBHBDB_00135 1.16e-15 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_00136 9.44e-40 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_00137 4.22e-13 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_00138 7.62e-41 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNEBHBDB_00139 7.72e-45 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KNEBHBDB_00140 1.78e-240 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KNEBHBDB_00141 0.0 XK27_09800 - - I - - - Acyltransferase
KNEBHBDB_00142 2.43e-47 - - - S - - - MORN repeat protein
KNEBHBDB_00143 3.25e-106 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNEBHBDB_00144 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNEBHBDB_00145 3.59e-123 flaR - - F - - - topology modulation protein
KNEBHBDB_00147 2.31e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00149 6.8e-200 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KNEBHBDB_00150 4.3e-249 - - - KLT - - - serine threonine protein kinase
KNEBHBDB_00151 1.89e-211 - - - KLT - - - serine threonine protein kinase
KNEBHBDB_00152 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
KNEBHBDB_00153 1.98e-17 - - - K - - - Transcriptional activator, Rgg GadR MutR family
KNEBHBDB_00154 9.8e-167 Z012_04635 - - K - - - sequence-specific DNA binding
KNEBHBDB_00156 1.55e-128 - - - C ko:K06871 - ko00000 Radical SAM
KNEBHBDB_00157 1.52e-150 - - - C ko:K06871 - ko00000 Radical SAM
KNEBHBDB_00158 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
KNEBHBDB_00159 3.28e-169 - - - L - - - Replication initiation factor
KNEBHBDB_00160 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
KNEBHBDB_00161 1.75e-277 - - - L - - - Belongs to the 'phage' integrase family
KNEBHBDB_00163 2.81e-81 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KNEBHBDB_00164 1.08e-170 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KNEBHBDB_00165 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNEBHBDB_00166 5.24e-258 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KNEBHBDB_00167 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
KNEBHBDB_00168 1.06e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KNEBHBDB_00169 4.43e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KNEBHBDB_00170 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNEBHBDB_00171 3.77e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KNEBHBDB_00172 1.16e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KNEBHBDB_00173 1.94e-05 - - - - - - - -
KNEBHBDB_00174 2.66e-307 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
KNEBHBDB_00175 1.53e-306 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KNEBHBDB_00176 2.22e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KNEBHBDB_00177 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNEBHBDB_00178 5.99e-194 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00179 1.01e-112 - - - L - - - Transposase
KNEBHBDB_00180 6.09e-40 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00181 4.39e-10 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00182 1.81e-114 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00183 6.32e-151 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_00184 2.6e-128 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNEBHBDB_00185 8.24e-56 - - - S ko:K01990 - ko00000,ko00002,ko02000 (ABC) transporter
KNEBHBDB_00186 1.67e-31 - - - S ko:K01990 - ko00000,ko00002,ko02000 (ABC) transporter
KNEBHBDB_00187 2.55e-22 - - - S ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KNEBHBDB_00188 2.86e-127 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
KNEBHBDB_00189 8.87e-45 - - - S ko:K01992 - ko00000,ko00002,ko02000 transport system, permease component
KNEBHBDB_00190 6.26e-80 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KNEBHBDB_00191 7.08e-96 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KNEBHBDB_00193 7.88e-123 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KNEBHBDB_00194 3.12e-53 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KNEBHBDB_00195 7.73e-156 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KNEBHBDB_00196 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KNEBHBDB_00197 1.2e-262 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
KNEBHBDB_00198 0.0 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
KNEBHBDB_00199 1.09e-143 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_00200 3.49e-217 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
KNEBHBDB_00201 2.69e-178 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_00202 6.45e-124 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KNEBHBDB_00203 5.93e-82 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
KNEBHBDB_00204 1.06e-128 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
KNEBHBDB_00205 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KNEBHBDB_00206 2.95e-304 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNEBHBDB_00207 5.03e-43 - - - - - - - -
KNEBHBDB_00208 1.82e-17 - - - - - - - -
KNEBHBDB_00209 5.57e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNEBHBDB_00210 2.61e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KNEBHBDB_00211 1.2e-140 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KNEBHBDB_00212 1.24e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNEBHBDB_00213 3.52e-227 - - - S - - - 37-kD nucleoid-associated bacterial protein
KNEBHBDB_00214 6.22e-128 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
KNEBHBDB_00215 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_00216 8.9e-130 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_00217 4.78e-224 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_00218 5.97e-274 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNEBHBDB_00219 5.96e-94 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
KNEBHBDB_00220 3.56e-185 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
KNEBHBDB_00221 2.03e-47 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNEBHBDB_00222 5.75e-301 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNEBHBDB_00223 6.91e-45 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00224 5.03e-43 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00225 1.45e-69 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00226 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
KNEBHBDB_00227 5.45e-266 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
KNEBHBDB_00228 2.71e-102 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
KNEBHBDB_00229 4.39e-233 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
KNEBHBDB_00233 1.87e-46 - - - S - - - Virulence-associated protein E
KNEBHBDB_00234 7.31e-31 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
KNEBHBDB_00235 1.64e-56 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
KNEBHBDB_00236 5.65e-226 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KNEBHBDB_00237 2.15e-297 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KNEBHBDB_00238 1.43e-159 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNEBHBDB_00239 1.32e-21 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNEBHBDB_00240 8.77e-21 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNEBHBDB_00241 1.97e-295 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KNEBHBDB_00242 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KNEBHBDB_00243 5.46e-185 - - - S - - - SseB protein N-terminal domain
KNEBHBDB_00244 7.75e-145 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
KNEBHBDB_00245 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KNEBHBDB_00246 2.1e-90 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNEBHBDB_00250 2.9e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNEBHBDB_00251 6.97e-121 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KNEBHBDB_00252 6.93e-170 yitS - - S - - - DegV family
KNEBHBDB_00253 0.000127 - - - K - - - PFAM helix-turn-helix domain protein
KNEBHBDB_00254 2e-24 - - - K - - - helix-turn-helix
KNEBHBDB_00255 2.32e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNEBHBDB_00256 3.18e-62 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KNEBHBDB_00257 1.34e-45 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KNEBHBDB_00258 1.95e-167 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KNEBHBDB_00259 2.99e-247 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
KNEBHBDB_00260 2.92e-11 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
KNEBHBDB_00261 7.99e-24 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KNEBHBDB_00262 2.95e-104 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KNEBHBDB_00266 4.01e-186 - - - F - - - Phosphorylase superfamily
KNEBHBDB_00267 9.88e-152 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
KNEBHBDB_00268 2.48e-09 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
KNEBHBDB_00269 3.53e-24 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
KNEBHBDB_00270 1.72e-30 - - - V - - - drug transmembrane transporter activity
KNEBHBDB_00271 3.29e-93 dinF - - V - - - Mate efflux family protein
KNEBHBDB_00272 1.84e-15 dinF - - V - - - Mate efflux family protein
KNEBHBDB_00273 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KNEBHBDB_00274 1e-109 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00275 5.43e-113 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00276 2.14e-150 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_00277 5.15e-13 - - - HJ - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_00278 9.25e-158 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNEBHBDB_00279 3.75e-18 - - - M - - - Acetyltransferase GNAT Family
KNEBHBDB_00280 2.78e-64 - - - K - - - Putative DNA-binding domain
KNEBHBDB_00281 3.06e-121 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
KNEBHBDB_00282 6.93e-15 - - - H - - - gamma-glutamylcysteine synthetase
KNEBHBDB_00283 2.93e-23 - - - H - - - gamma-glutamylcysteine synthetase
KNEBHBDB_00284 3.72e-74 - 6.3.2.2 - H ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 ergothioneine biosynthetic process
KNEBHBDB_00285 7.76e-100 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Cytosine-specific methyltransferase
KNEBHBDB_00286 1.85e-29 - - - - - - - -
KNEBHBDB_00287 3.3e-139 - - - K - - - Peptidase S24-like protein
KNEBHBDB_00288 1.44e-161 - - - E - - - IrrE N-terminal-like domain
KNEBHBDB_00290 7.43e-61 - - - K - - - Transcriptional
KNEBHBDB_00291 4.75e-57 - - - - - - - -
KNEBHBDB_00292 2.5e-94 - - - - - - - -
KNEBHBDB_00293 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
KNEBHBDB_00294 7.83e-283 - - - K - - - Replication initiation factor
KNEBHBDB_00295 2.71e-44 - - - - - - - -
KNEBHBDB_00296 2.42e-112 - - - - - - - -
KNEBHBDB_00297 5.73e-204 - - - S - - - Conjugative transposon protein TcpC
KNEBHBDB_00298 7.96e-45 - - - - - - - -
KNEBHBDB_00299 8.81e-89 - - - S - - - TcpE family
KNEBHBDB_00300 0.0 yddE - - S - - - AAA-like domain
KNEBHBDB_00301 2.32e-272 - - - - - - - -
KNEBHBDB_00302 2.58e-41 - - - - - - - -
KNEBHBDB_00303 1.91e-82 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
KNEBHBDB_00304 1.5e-139 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KNEBHBDB_00305 9.79e-125 cps1C - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KNEBHBDB_00306 1.63e-139 - - - L - - - Transposase
KNEBHBDB_00307 6.66e-136 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_00308 7.08e-213 - - - L ko:K07481 - ko00000 transposase, IS4 family
KNEBHBDB_00309 5.71e-91 - - - V - - - VanZ like family
KNEBHBDB_00310 6.91e-164 - - - L ko:K07498 - ko00000 DDE domain
KNEBHBDB_00311 1.79e-197 tra981A - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
KNEBHBDB_00312 1.71e-143 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KNEBHBDB_00313 7.87e-13 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
KNEBHBDB_00314 7.18e-181 - - - C ko:K06871 - ko00000 Arylsulfatase regulator (Fe-S oxidoreductase)
KNEBHBDB_00315 2.02e-248 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 (ABC) transporter
KNEBHBDB_00316 1.78e-68 - - - K - - - Acetyltransferase GNAT Family
KNEBHBDB_00317 0.0 - - - S - - - Protein of unknown function (DUF3114)
KNEBHBDB_00320 3.71e-101 - - - L ko:K07498 - ko00000 Transposase
KNEBHBDB_00321 1.18e-14 - - - L - - - Transposase
KNEBHBDB_00323 4.64e-94 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Psort location CytoplasmicMembrane, score 10.00
KNEBHBDB_00324 5.69e-24 asp - - S - - - cog cog1302
KNEBHBDB_00325 9.21e-287 norN - - V - - - Mate efflux family protein
KNEBHBDB_00326 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
KNEBHBDB_00327 2.17e-96 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KNEBHBDB_00328 1.03e-88 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KNEBHBDB_00329 7.3e-160 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KNEBHBDB_00330 1.36e-61 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KNEBHBDB_00331 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KNEBHBDB_00332 2.25e-50 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KNEBHBDB_00333 1.18e-83 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KNEBHBDB_00334 4.84e-86 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KNEBHBDB_00335 1.27e-13 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KNEBHBDB_00336 6.11e-18 treP 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_00337 2.56e-74 treB 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS System
KNEBHBDB_00338 2.66e-29 treR - - K ko:K03486,ko:K03710 - ko00000,ko03000 DNA-binding transcription factor activity
KNEBHBDB_00339 9.24e-114 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
KNEBHBDB_00340 1.17e-122 ywlG - - S - - - Belongs to the UPF0340 family
KNEBHBDB_00343 2.2e-51 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
KNEBHBDB_00347 2.15e-27 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KNEBHBDB_00348 1.55e-24 - - - K - - - transcriptional
KNEBHBDB_00349 1.1e-280 - - - L - - - Belongs to the 'phage' integrase family
KNEBHBDB_00351 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KNEBHBDB_00352 7.6e-212 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
KNEBHBDB_00353 3.11e-132 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KNEBHBDB_00354 1.62e-266 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KNEBHBDB_00355 6.69e-122 - - - S - - - ECF transporter, substrate-specific component
KNEBHBDB_00356 7.19e-119 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNEBHBDB_00357 6.6e-158 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
KNEBHBDB_00358 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KNEBHBDB_00359 1.01e-114 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_00360 4.29e-50 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_00361 2.72e-16 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_00362 3.67e-144 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_00363 6.83e-99 - - - L ko:K07497 - ko00000 integrase core domain
KNEBHBDB_00364 1.31e-119 - - - L - - - DNA mismatch repair enzyme MutH
KNEBHBDB_00367 1.15e-259 - - - S - - - AAA ATPase domain
KNEBHBDB_00368 7.11e-59 - - - O - - - Protein conserved in bacteria
KNEBHBDB_00369 1.25e-89 - - - - - - - -
KNEBHBDB_00370 1.18e-159 - - - O - - - AAA domain (Cdc48 subfamily)
KNEBHBDB_00371 1.35e-28 - - - - - - - -
KNEBHBDB_00372 4.36e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00373 0.000353 - - - S - - - TraX protein
KNEBHBDB_00374 8.63e-46 - - - S - - - TraX protein
KNEBHBDB_00375 8.66e-56 - - - S - - - TraX protein
KNEBHBDB_00376 1.18e-122 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
KNEBHBDB_00377 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KNEBHBDB_00378 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNEBHBDB_00379 9.79e-181 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
KNEBHBDB_00380 1.46e-261 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNEBHBDB_00381 8.41e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNEBHBDB_00382 8.2e-306 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KNEBHBDB_00383 1.67e-166 - - - S - - - CHAP domain
KNEBHBDB_00384 8.38e-46 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00385 2.75e-13 - - - L ko:K07483 - ko00000 Transposase
KNEBHBDB_00386 6.55e-69 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_00387 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KNEBHBDB_00388 4.04e-53 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNEBHBDB_00389 9.23e-214 - - - K - - - transcriptional regulator (lysR family)
KNEBHBDB_00390 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNEBHBDB_00395 3.07e-242 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KNEBHBDB_00396 1.12e-90 sip - - M - - - LysM domain protein
KNEBHBDB_00397 9.63e-180 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
KNEBHBDB_00398 1.34e-115 mreD - - M ko:K03571 - ko00000,ko03036 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KNEBHBDB_00399 1.36e-179 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KNEBHBDB_00414 2.02e-30 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KNEBHBDB_00415 1.62e-181 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KNEBHBDB_00416 4.65e-57 - - - - - - - -
KNEBHBDB_00417 9.43e-37 - - - - - - - -
KNEBHBDB_00419 2.23e-171 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KNEBHBDB_00420 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KNEBHBDB_00421 0.0 - - - V - - - Type I restriction enzyme R protein N terminus (HSDR_N)
KNEBHBDB_00422 9.52e-115 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KNEBHBDB_00423 3.63e-24 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KNEBHBDB_00424 4.48e-59 - - - S - - - Protein of unknown function (DUF2974)
KNEBHBDB_00425 3.3e-27 - - - S - - - Protein of unknown function (DUF2974)
KNEBHBDB_00426 9.97e-30 - - - S - - - Protein of unknown function (DUF2974)
KNEBHBDB_00427 6.94e-146 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNEBHBDB_00428 1.14e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
KNEBHBDB_00429 4.02e-196 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
KNEBHBDB_00430 1.85e-24 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNEBHBDB_00431 4.6e-29 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNEBHBDB_00432 2.07e-149 pgm - - G - - - Phosphoglycerate mutase
KNEBHBDB_00433 2.2e-222 - - - S ko:K07025 - ko00000 hydrolase
KNEBHBDB_00434 7.61e-30 - - - - - - - -
KNEBHBDB_00435 1.91e-10 - - - M - - - LysM domain
KNEBHBDB_00436 1.32e-53 - - - M - - - LysM domain
KNEBHBDB_00437 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KNEBHBDB_00440 5.2e-62 yegS - - I - - - Diacylglycerol kinase
KNEBHBDB_00441 3.11e-67 yegS 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 lipid kinase activity
KNEBHBDB_00442 1.25e-125 - - - S - - - Hydrophobic domain protein
KNEBHBDB_00444 1.61e-44 ytgB - - S - - - Membrane
KNEBHBDB_00445 1.32e-131 - - - - - - - -
KNEBHBDB_00446 1.07e-32 - - - S - - - Small integral membrane protein
KNEBHBDB_00447 1.31e-116 - - - M - - - Protein conserved in bacteria
KNEBHBDB_00448 1.17e-34 - - - K - - - CsbD-like
KNEBHBDB_00449 1.18e-127 XK27_06885 - - L - - - hydrolase
KNEBHBDB_00450 2.69e-11 XK27_06885 - - L - - - hydrolase
KNEBHBDB_00451 1.3e-26 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
KNEBHBDB_00452 4.32e-33 - - - K ko:K10947 - ko00000,ko03000 negative regulation of transcription, DNA-templated
KNEBHBDB_00453 1.91e-10 - - - S - - - Protein of unknown function (DUF1700)
KNEBHBDB_00454 1.79e-27 - - - S - - - Protein of unknown function (DUF1700)
KNEBHBDB_00455 1.17e-146 - - - S - - - Putative adhesin
KNEBHBDB_00456 6.75e-236 XK27_06930 - - V ko:K01421 - ko00000 domain protein
KNEBHBDB_00457 6.06e-84 XK27_06935 - - K - - - transcriptional regulator
KNEBHBDB_00458 1.31e-55 ypaA - - S ko:K08987 - ko00000 membrane
KNEBHBDB_00459 4.28e-30 - - - S - - - Glycosyl transferase family 2
KNEBHBDB_00460 9e-06 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
KNEBHBDB_00461 7.92e-107 rgpX3 - - S - - - polysaccharide biosynthetic process
KNEBHBDB_00462 5.42e-156 rgpX3 - - S - - - polysaccharide biosynthetic process
KNEBHBDB_00463 1.98e-236 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
KNEBHBDB_00464 5.93e-288 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
KNEBHBDB_00465 4.38e-105 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KNEBHBDB_00466 1.04e-104 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KNEBHBDB_00467 3.89e-184 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KNEBHBDB_00468 3.31e-263 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KNEBHBDB_00469 9.33e-252 rgpE - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 COG0463 Glycosyltransferases involved in cell wall biogenesis
KNEBHBDB_00470 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
KNEBHBDB_00471 5.62e-155 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KNEBHBDB_00472 1.1e-167 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
KNEBHBDB_00473 5.5e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNEBHBDB_00474 1.77e-78 XK27_04120 - - S - - - Putative amino acid metabolism
KNEBHBDB_00475 1.12e-264 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KNEBHBDB_00476 1.28e-59 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNEBHBDB_00477 2.11e-182 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KNEBHBDB_00478 2.09e-244 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KNEBHBDB_00479 4.18e-06 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
KNEBHBDB_00480 7.77e-59 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
KNEBHBDB_00481 7.48e-09 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
KNEBHBDB_00483 7.33e-152 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNEBHBDB_00484 2.09e-41 - - - - - - - -
KNEBHBDB_00485 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
KNEBHBDB_00486 1.71e-213 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNEBHBDB_00487 6.01e-94 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNEBHBDB_00489 2.17e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KNEBHBDB_00490 6.83e-228 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
KNEBHBDB_00491 2.38e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KNEBHBDB_00492 1.14e-195 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KNEBHBDB_00493 6.85e-123 - - - J ko:K09962 - ko00000 protein conserved in bacteria
KNEBHBDB_00494 1.9e-316 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNEBHBDB_00495 8.72e-167 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
KNEBHBDB_00496 6.51e-232 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 transporter
KNEBHBDB_00497 4.37e-230 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
KNEBHBDB_00498 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
KNEBHBDB_00499 3.09e-291 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KNEBHBDB_00500 4.04e-223 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
KNEBHBDB_00501 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
KNEBHBDB_00502 1.47e-22 - - - - - - - -
KNEBHBDB_00503 0.0 - - - M - - - family 8
KNEBHBDB_00504 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KNEBHBDB_00505 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KNEBHBDB_00506 1.66e-76 yhaI - - L - - - Membrane
KNEBHBDB_00507 9.63e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KNEBHBDB_00508 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNEBHBDB_00509 9.44e-184 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KNEBHBDB_00510 6.74e-115 - - - S ko:K06889 - ko00000 thiolester hydrolase activity
KNEBHBDB_00511 7.03e-53 napB - - K - - - transcriptional
KNEBHBDB_00513 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KNEBHBDB_00514 2.29e-176 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
KNEBHBDB_00515 3.82e-47 cof - - Q - - - phosphatase activity
KNEBHBDB_00516 1.17e-73 cof - - Q - - - phosphatase activity
KNEBHBDB_00517 7.49e-58 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
KNEBHBDB_00518 9.01e-75 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
KNEBHBDB_00519 5.23e-153 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KNEBHBDB_00520 1.11e-134 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
KNEBHBDB_00521 8.93e-122 nirJ - - C ko:K06139,ko:K22227 - ko00000 radical SAM domain protein
KNEBHBDB_00524 4.85e-201 - - - K - - - Transcriptional activator, Rgg GadR MutR family
KNEBHBDB_00525 3.63e-71 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
KNEBHBDB_00526 0.000789 - - - S - - - Toxin-antitoxin system, toxin component, RelE family
KNEBHBDB_00529 6.36e-239 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNEBHBDB_00530 1.63e-168 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNEBHBDB_00531 4.12e-58 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
KNEBHBDB_00532 6.83e-66 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
KNEBHBDB_00533 4.95e-63 pspE - - P ko:K03972 - ko00000 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNEBHBDB_00534 1.01e-99 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KNEBHBDB_00535 4.19e-197 XK27_05470 - - E - - - Methionine synthase
KNEBHBDB_00536 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNEBHBDB_00537 6.53e-208 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KNEBHBDB_00538 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KNEBHBDB_00539 3.19e-146 spi 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KNEBHBDB_00540 1.66e-38 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNEBHBDB_00541 1.5e-103 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNEBHBDB_00542 1.71e-34 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KNEBHBDB_00543 3.39e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
KNEBHBDB_00544 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNEBHBDB_00545 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNEBHBDB_00552 4.58e-132 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
KNEBHBDB_00553 7.09e-104 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
KNEBHBDB_00554 1.51e-57 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KNEBHBDB_00555 8.68e-99 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
KNEBHBDB_00556 2.42e-147 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KNEBHBDB_00557 7.16e-77 hsdS 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K07317 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KNEBHBDB_00558 3.96e-188 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00559 1.28e-67 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00560 1.03e-126 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
KNEBHBDB_00561 4.16e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KNEBHBDB_00562 3.63e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KNEBHBDB_00563 5.68e-135 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KNEBHBDB_00564 1.02e-66 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00565 2.56e-49 - - - L - - - Transposase, Mutator family
KNEBHBDB_00566 1.22e-52 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00567 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
KNEBHBDB_00568 1.36e-287 - - - L - - - Transposase, Mutator family
KNEBHBDB_00569 4.17e-98 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNEBHBDB_00570 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KNEBHBDB_00571 1.47e-47 - - - K - - - sequence-specific DNA binding
KNEBHBDB_00573 7.8e-94 - - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
KNEBHBDB_00574 0.0 - - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
KNEBHBDB_00575 7.85e-293 spaC2 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
KNEBHBDB_00576 2e-231 - - - EGP - - - Major Facilitator Superfamily
KNEBHBDB_00577 2.42e-151 - - - - - - - -
KNEBHBDB_00578 5.72e-05 - - - - - - - -
KNEBHBDB_00579 1.27e-32 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
KNEBHBDB_00580 6.53e-118 - - - L ko:K07498 - ko00000 Transposase
KNEBHBDB_00581 4.59e-194 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
KNEBHBDB_00582 5.56e-71 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
KNEBHBDB_00583 2.3e-34 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
KNEBHBDB_00584 3.12e-113 isaA - - M - - - Immunodominant staphylococcal antigen A
KNEBHBDB_00585 1.6e-121 lytE - - M - - - LysM domain protein
KNEBHBDB_00586 5.05e-129 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNEBHBDB_00587 7.37e-35 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNEBHBDB_00588 2.6e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNEBHBDB_00589 4.68e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNEBHBDB_00590 5.4e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNEBHBDB_00591 6.23e-185 ymfM - - S ko:K15539 - ko00000 sequence-specific DNA binding
KNEBHBDB_00592 7.32e-307 ymfH - - S - - - Peptidase M16
KNEBHBDB_00593 2.15e-299 albE - - S - - - Peptidase M16
KNEBHBDB_00594 3.7e-69 yaaA - - S - - - S4 domain protein YaaA
KNEBHBDB_00595 2.24e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNEBHBDB_00596 6.74e-39 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KNEBHBDB_00597 3.14e-296 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KNEBHBDB_00598 5.52e-150 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNEBHBDB_00599 1.67e-110 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00600 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNEBHBDB_00601 8.81e-30 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNEBHBDB_00602 3.16e-196 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNEBHBDB_00603 1.27e-59 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNEBHBDB_00604 1.57e-105 XK27_09675 - - K ko:K07105 - ko00000 -acetyltransferase
KNEBHBDB_00605 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KNEBHBDB_00606 3.69e-27 XK27_11680 - - - - - - -
KNEBHBDB_00607 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
KNEBHBDB_00608 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KNEBHBDB_00609 6.04e-101 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KNEBHBDB_00610 1.29e-161 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KNEBHBDB_00611 2.65e-91 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KNEBHBDB_00612 1.04e-82 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KNEBHBDB_00613 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNEBHBDB_00614 1.35e-243 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNEBHBDB_00615 1.01e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KNEBHBDB_00616 1.01e-251 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KNEBHBDB_00617 1.67e-250 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KNEBHBDB_00618 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNEBHBDB_00620 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KNEBHBDB_00621 2.37e-220 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
KNEBHBDB_00622 9.26e-19 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_00623 8.45e-167 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KNEBHBDB_00624 2.04e-201 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KNEBHBDB_00625 1.28e-94 - - - L - - - Transposase
KNEBHBDB_00626 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
KNEBHBDB_00627 2.51e-101 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
KNEBHBDB_00628 4.9e-21 - - - V ko:K18996,ko:K19171 - ko00000,ko02048,ko03032 (ABC) transporter
KNEBHBDB_00629 5.26e-16 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_00630 1.91e-44 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_00631 1.94e-25 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
KNEBHBDB_00632 2.24e-47 zmpB - - M ko:K08643 - ko00000,ko01000,ko01002 M26 IgA1-specific Metallo-endopeptidase C-terminal region
KNEBHBDB_00633 2.6e-247 - - - M ko:K08643 - ko00000,ko01000,ko01002 translation initiation factor activity
KNEBHBDB_00634 1.18e-34 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00635 1.7e-13 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00637 3.25e-209 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KNEBHBDB_00638 6.12e-278 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNEBHBDB_00639 5.61e-264 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
KNEBHBDB_00640 8.52e-55 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
KNEBHBDB_00641 2.93e-165 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KNEBHBDB_00642 1.99e-64 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KNEBHBDB_00643 1.3e-127 yvgN - - C - - - reductase
KNEBHBDB_00644 7.53e-40 yvgN - - C - - - reductase
KNEBHBDB_00645 1.23e-06 - - - S - - - Protein of unknown function (DUF1275)
KNEBHBDB_00646 2.02e-43 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KNEBHBDB_00647 5.59e-107 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KNEBHBDB_00648 1.25e-248 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KNEBHBDB_00649 1.82e-184 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KNEBHBDB_00650 1.7e-298 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KNEBHBDB_00651 2.83e-82 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNEBHBDB_00652 1.54e-191 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNEBHBDB_00653 2.78e-98 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KNEBHBDB_00654 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KNEBHBDB_00655 7.01e-23 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KNEBHBDB_00656 4.69e-179 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KNEBHBDB_00657 1.6e-36 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNEBHBDB_00658 4.2e-66 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNEBHBDB_00659 1.5e-74 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNEBHBDB_00660 2.36e-38 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00661 3.3e-43 oppD - - P ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00662 9.77e-88 - - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00663 4.16e-58 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00664 6.98e-81 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00665 3.74e-119 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_00666 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KNEBHBDB_00667 2.76e-135 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KNEBHBDB_00668 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNEBHBDB_00669 6.48e-245 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNEBHBDB_00670 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KNEBHBDB_00671 2.36e-243 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
KNEBHBDB_00672 6.28e-66 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KNEBHBDB_00673 4.43e-82 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KNEBHBDB_00674 2.84e-29 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KNEBHBDB_00675 4.88e-125 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KNEBHBDB_00676 6.15e-36 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 phosphorylase activity
KNEBHBDB_00677 4.77e-107 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
KNEBHBDB_00678 1.38e-21 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
KNEBHBDB_00679 1.22e-222 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KNEBHBDB_00680 1.98e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
KNEBHBDB_00681 4.41e-19 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
KNEBHBDB_00682 7.42e-78 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
KNEBHBDB_00683 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
KNEBHBDB_00684 6.19e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00686 2.79e-127 - - - - - - - -
KNEBHBDB_00688 4.98e-14 - - - - - - - -
KNEBHBDB_00689 3.05e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KNEBHBDB_00690 1.23e-170 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_00691 6.72e-193 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KNEBHBDB_00692 7.42e-181 ytmP - - M - - - Phosphotransferase
KNEBHBDB_00693 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KNEBHBDB_00695 1.18e-214 ytfP - - S ko:K07007 - ko00000 Flavoprotein
KNEBHBDB_00696 3.22e-28 ytfP - - S ko:K07007 - ko00000 Flavoprotein
KNEBHBDB_00697 8.64e-159 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KNEBHBDB_00698 3.32e-38 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KNEBHBDB_00699 3.4e-92 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KNEBHBDB_00700 2.98e-113 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
KNEBHBDB_00701 3.91e-67 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
KNEBHBDB_00702 2.54e-226 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
KNEBHBDB_00703 2.67e-56 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KNEBHBDB_00704 1.82e-178 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KNEBHBDB_00705 3.59e-127 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNEBHBDB_00706 1.94e-155 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNEBHBDB_00707 1.02e-175 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KNEBHBDB_00708 3.52e-111 ykuL - - S - - - CBS domain
KNEBHBDB_00709 4.53e-127 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KNEBHBDB_00710 4.69e-236 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNEBHBDB_00711 8.37e-128 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KNEBHBDB_00712 1.59e-46 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KNEBHBDB_00713 6.74e-102 - - - K - - - transcriptional regulator
KNEBHBDB_00714 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KNEBHBDB_00717 2.43e-145 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KNEBHBDB_00718 1.63e-90 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
KNEBHBDB_00719 5.63e-168 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNEBHBDB_00720 3.44e-31 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNEBHBDB_00721 2.72e-299 femA 2.3.2.17 - V ko:K11694 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
KNEBHBDB_00723 2.31e-50 - 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KNEBHBDB_00724 1.02e-29 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KNEBHBDB_00725 2.81e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNEBHBDB_00726 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNEBHBDB_00727 2.15e-63 ylxQ - - J - - - ribosomal protein
KNEBHBDB_00728 6.68e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
KNEBHBDB_00729 4.29e-260 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KNEBHBDB_00730 1.54e-96 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KNEBHBDB_00731 6.32e-27 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNEBHBDB_00732 2.56e-151 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNEBHBDB_00733 1.34e-47 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNEBHBDB_00734 4.59e-75 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
KNEBHBDB_00737 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNEBHBDB_00738 2.52e-119 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNEBHBDB_00739 1.75e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNEBHBDB_00740 6.97e-52 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KNEBHBDB_00741 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KNEBHBDB_00742 2.07e-25 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNEBHBDB_00743 8.85e-113 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNEBHBDB_00744 1.92e-161 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNEBHBDB_00745 4.64e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KNEBHBDB_00749 3.31e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KNEBHBDB_00750 1.66e-143 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KNEBHBDB_00751 1.3e-204 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KNEBHBDB_00752 6.87e-39 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
KNEBHBDB_00753 4.97e-211 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
KNEBHBDB_00754 1.85e-130 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
KNEBHBDB_00755 9.64e-29 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
KNEBHBDB_00756 2.35e-58 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNEBHBDB_00758 1.49e-60 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNEBHBDB_00759 6.46e-145 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KNEBHBDB_00760 1.62e-37 mesH - - S - - - GtrA-like protein
KNEBHBDB_00761 2.63e-232 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNEBHBDB_00762 6.71e-59 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KNEBHBDB_00763 9.99e-38 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KNEBHBDB_00764 5.95e-82 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
KNEBHBDB_00765 4.73e-148 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
KNEBHBDB_00766 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
KNEBHBDB_00767 5.26e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNEBHBDB_00768 4.79e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
KNEBHBDB_00769 3.74e-143 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_00770 8.36e-66 malX - - G ko:K02027,ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 maltose binding
KNEBHBDB_00771 9.69e-25 malX - - G ko:K02027,ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 maltose binding
KNEBHBDB_00772 3.39e-24 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNEBHBDB_00773 1.33e-162 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KNEBHBDB_00774 6.53e-52 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KNEBHBDB_00775 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KNEBHBDB_00776 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KNEBHBDB_00778 4.97e-71 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KNEBHBDB_00779 1.84e-103 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KNEBHBDB_00780 7.13e-26 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNEBHBDB_00781 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KNEBHBDB_00782 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_00783 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_00784 3.76e-48 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_00785 9.27e-64 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KNEBHBDB_00786 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KNEBHBDB_00787 7.82e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KNEBHBDB_00788 5.47e-66 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
KNEBHBDB_00789 3.11e-67 ydgJ 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 inositol 2-dehydrogenase activity
KNEBHBDB_00790 1.61e-36 - 2.7.7.15 - S ko:K00968 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 inositol 2-dehydrogenase activity
KNEBHBDB_00791 4.54e-11 - - - S - - - oxidoreductase
KNEBHBDB_00792 3.14e-294 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
KNEBHBDB_00793 4.34e-91 - - - M - - - Pfam SNARE associated Golgi protein
KNEBHBDB_00794 4.27e-130 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
KNEBHBDB_00797 3.23e-188 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
KNEBHBDB_00798 1.45e-41 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
KNEBHBDB_00801 1.21e-182 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
KNEBHBDB_00802 1.49e-66 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
KNEBHBDB_00803 8.28e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KNEBHBDB_00804 1.12e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
KNEBHBDB_00805 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
KNEBHBDB_00806 1.09e-173 - - - S - - - Putative SAM-dependent methyltransferase
KNEBHBDB_00807 7.25e-26 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNEBHBDB_00808 3.66e-47 yknX - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNEBHBDB_00809 4.11e-47 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
KNEBHBDB_00810 9.33e-12 - - - V - - - efflux transmembrane transporter activity
KNEBHBDB_00811 1.01e-39 - - - V ko:K02004 - ko00000,ko00002,ko02000 efflux transmembrane transporter activity
KNEBHBDB_00812 3.48e-32 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
KNEBHBDB_00814 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KNEBHBDB_00815 1.02e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KNEBHBDB_00816 8.04e-158 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KNEBHBDB_00817 7.96e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KNEBHBDB_00818 2.05e-257 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KNEBHBDB_00819 2.87e-16 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNEBHBDB_00820 4.73e-242 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNEBHBDB_00821 3.57e-260 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KNEBHBDB_00822 1.48e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
KNEBHBDB_00823 3.74e-124 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KNEBHBDB_00824 1.04e-83 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KNEBHBDB_00825 1.91e-257 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KNEBHBDB_00826 2.72e-50 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNEBHBDB_00827 3.46e-223 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNEBHBDB_00828 2.47e-28 bglC - - K - - - Transcriptional regulator
KNEBHBDB_00829 5.89e-78 yfiF3 - - K - - - sequence-specific DNA binding
KNEBHBDB_00830 3.23e-51 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 nucleotide catabolic process
KNEBHBDB_00831 2.6e-291 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_00832 1.07e-09 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_00833 7.45e-31 yecS - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 amino acid transport
KNEBHBDB_00834 4.37e-35 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_00835 1.25e-16 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KNEBHBDB_00836 5.07e-127 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KNEBHBDB_00837 1.81e-134 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KNEBHBDB_00838 2.66e-94 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_00839 1.24e-132 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNEBHBDB_00840 9.02e-163 dnaD - - - ko:K02086 - ko00000 -
KNEBHBDB_00841 3.99e-232 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNEBHBDB_00842 6.44e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNEBHBDB_00843 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
KNEBHBDB_00844 3.67e-178 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KNEBHBDB_00845 1.27e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KNEBHBDB_00846 1.16e-116 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
KNEBHBDB_00847 2.76e-15 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNEBHBDB_00848 6.82e-57 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KNEBHBDB_00849 6.37e-74 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KNEBHBDB_00850 2.7e-162 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNEBHBDB_00851 3.56e-68 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNEBHBDB_00852 1.11e-142 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KNEBHBDB_00853 1.3e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KNEBHBDB_00854 2.15e-18 acuB - - S ko:K04767 - ko00000 IMP dehydrogenase activity
KNEBHBDB_00855 2e-79 XK27_04065 - - S ko:K04767 - ko00000 CBS domain
KNEBHBDB_00856 1.32e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KNEBHBDB_00857 6.57e-176 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KNEBHBDB_00858 2.06e-95 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNEBHBDB_00859 3.03e-81 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNEBHBDB_00860 2.55e-34 XK27_12120 - - E - - - AzlC protein
KNEBHBDB_00861 2.61e-169 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNEBHBDB_00862 1.34e-52 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNEBHBDB_00863 2.84e-54 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KNEBHBDB_00864 2.39e-156 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
KNEBHBDB_00865 6.45e-45 ykzG - - S - - - Belongs to the UPF0356 family
KNEBHBDB_00866 5.72e-235 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNEBHBDB_00867 3.98e-140 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNEBHBDB_00868 3.96e-54 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
KNEBHBDB_00869 1.38e-63 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KNEBHBDB_00870 9.64e-193 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KNEBHBDB_00871 2.15e-34 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
KNEBHBDB_00872 3.77e-37 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
KNEBHBDB_00873 1.53e-113 - - - S - - - Fusaric acid resistance protein-like
KNEBHBDB_00874 9.88e-17 - - - - - - - -
KNEBHBDB_00875 5.03e-43 - - - - - - - -
KNEBHBDB_00876 1.35e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KNEBHBDB_00877 1.44e-55 - - - L ko:K07491 - ko00000 Transposase
KNEBHBDB_00878 8.72e-58 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_00879 1.74e-30 - - - L - - - Transposase
KNEBHBDB_00880 1.8e-72 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00881 2.64e-24 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00882 1.86e-21 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KNEBHBDB_00883 4.25e-187 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KNEBHBDB_00884 9.48e-43 copZ - - P - - - Heavy metal-associated domain protein
KNEBHBDB_00885 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KNEBHBDB_00886 1.23e-96 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
KNEBHBDB_00887 5.57e-133 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KNEBHBDB_00888 2.38e-222 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KNEBHBDB_00889 1.83e-55 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KNEBHBDB_00890 1.12e-130 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
KNEBHBDB_00891 3.81e-59 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KNEBHBDB_00892 2.13e-57 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KNEBHBDB_00893 2.47e-227 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNEBHBDB_00894 5.7e-90 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
KNEBHBDB_00895 3.22e-156 - - - L - - - Transposase
KNEBHBDB_00896 9.62e-116 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KNEBHBDB_00897 3.4e-33 - - - S - - - Mitochondrial biogenesis AIM24
KNEBHBDB_00898 1.15e-47 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
KNEBHBDB_00899 1.64e-16 - - - S - - - Mitochondrial biogenesis AIM24
KNEBHBDB_00900 5.98e-87 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNEBHBDB_00901 5.75e-23 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNEBHBDB_00902 8.74e-46 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNEBHBDB_00903 2.98e-104 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KNEBHBDB_00904 3.06e-27 XK27_09620 - - S - - - FMN reductase (NADPH) activity
KNEBHBDB_00905 6.98e-99 - - - S - - - reductase
KNEBHBDB_00906 5.96e-75 XK27_09615 - - C ko:K19784 - ko00000 reductase
KNEBHBDB_00907 2.06e-177 XK27_09615 - - C ko:K19784 - ko00000 reductase
KNEBHBDB_00908 1.08e-10 nirC_1 - - P - - - Formate nitrite transporter
KNEBHBDB_00909 2.8e-118 nirC_1 - - P - - - Formate nitrite transporter
KNEBHBDB_00910 1.91e-63 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KNEBHBDB_00911 1.77e-156 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KNEBHBDB_00912 3.15e-48 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KNEBHBDB_00913 2.92e-40 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KNEBHBDB_00914 1.3e-152 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KNEBHBDB_00915 3.65e-122 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KNEBHBDB_00917 1.43e-127 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNEBHBDB_00918 1.81e-81 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNEBHBDB_00919 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
KNEBHBDB_00920 2.42e-84 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
KNEBHBDB_00921 6.24e-30 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonate dehydratase activity
KNEBHBDB_00922 1.55e-110 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNEBHBDB_00923 5.03e-67 hsdS_1 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KNEBHBDB_00924 2.15e-41 - - - D - - - nuclear chromosome segregation
KNEBHBDB_00925 8.98e-100 - - - L ko:K04763 - ko00000,ko03036 DNA integration
KNEBHBDB_00926 3.45e-112 XK27_05540 - - S - - - Gram-negative-bacterium-type cell wall biogenesis
KNEBHBDB_00928 4.07e-304 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
KNEBHBDB_00929 6.98e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNEBHBDB_00931 7.54e-99 XK27_03180 - - T - - - universal stress protein
KNEBHBDB_00932 6.9e-141 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KNEBHBDB_00933 5.08e-146 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KNEBHBDB_00934 9.07e-19 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KNEBHBDB_00935 1.26e-107 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KNEBHBDB_00936 3.02e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
KNEBHBDB_00937 1.15e-34 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KNEBHBDB_00938 5.04e-288 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNEBHBDB_00940 2.57e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KNEBHBDB_00941 5.8e-18 - - - G - - - Domain of unknown function (DUF4832)
KNEBHBDB_00942 3.46e-224 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNEBHBDB_00943 1.95e-222 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KNEBHBDB_00944 1.94e-164 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KNEBHBDB_00945 6.37e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNEBHBDB_00946 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KNEBHBDB_00947 4.85e-258 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KNEBHBDB_00948 7.45e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KNEBHBDB_00949 4.12e-142 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
KNEBHBDB_00950 2.54e-72 hmpT - - S - - - membrane
KNEBHBDB_00951 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KNEBHBDB_00952 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KNEBHBDB_00953 1.28e-108 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KNEBHBDB_00954 1.89e-73 WQ51_06355 - - S - - - TM2 domain
KNEBHBDB_00955 1.35e-56 - - - - - - - -
KNEBHBDB_00958 9.82e-45 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_00959 8.09e-67 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_00960 2.75e-13 - - - L ko:K07483 - ko00000 Transposase
KNEBHBDB_00961 1.28e-32 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_00962 1.08e-19 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNEBHBDB_00963 3.78e-211 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNEBHBDB_00964 2.78e-29 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNEBHBDB_00965 6.13e-104 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_00966 5.15e-23 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
KNEBHBDB_00967 3.17e-120 yvqF - - KT ko:K11622 ko02020,map02020 ko00000,ko00001 membrane
KNEBHBDB_00968 1.63e-12 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
KNEBHBDB_00969 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KNEBHBDB_00970 7.75e-170 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KNEBHBDB_00971 9.42e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNEBHBDB_00972 6.31e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNEBHBDB_00973 3.79e-128 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNEBHBDB_00974 1.41e-142 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNEBHBDB_00975 1.14e-222 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNEBHBDB_00976 6.93e-55 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KNEBHBDB_00977 5.86e-39 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 AIR synthase related protein, N-terminal domain
KNEBHBDB_00978 1.12e-30 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KNEBHBDB_00979 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNEBHBDB_00980 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNEBHBDB_00981 9.89e-58 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNEBHBDB_00982 6.16e-102 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KNEBHBDB_00983 3.87e-48 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KNEBHBDB_00984 1.38e-19 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNEBHBDB_00985 1.72e-32 - - - E - - - GDSL-like Lipase/Acylhydrolase
KNEBHBDB_00986 1.23e-60 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
KNEBHBDB_00987 2.02e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
KNEBHBDB_00989 5.26e-56 - - - - - - - -
KNEBHBDB_00990 1.51e-18 - - - - - - - -
KNEBHBDB_00991 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNEBHBDB_00992 1.23e-124 mip - - S - - - hydroperoxide reductase activity
KNEBHBDB_00993 2e-241 - - - I - - - acyl-CoA dehydrogenase
KNEBHBDB_00994 6.57e-192 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 C4-dicarboxylate transporter malic acid transport
KNEBHBDB_00995 0.0 msrR - - K - - - Transcriptional regulator
KNEBHBDB_00996 1.34e-194 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KNEBHBDB_00997 4.42e-35 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNEBHBDB_00998 6.06e-37 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNEBHBDB_00999 1.51e-43 XK27_10395 - - S - - - membrane
KNEBHBDB_01000 4.18e-78 yvjA - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNEBHBDB_01001 0.0 ykpA - - S - - - abc transporter atp-binding protein
KNEBHBDB_01002 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
KNEBHBDB_01006 1.85e-74 yveI - - S - - - Psort location CytoplasmicMembrane, score
KNEBHBDB_01007 1.39e-47 yveI - - S - - - Psort location CytoplasmicMembrane, score
KNEBHBDB_01008 3.72e-51 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KNEBHBDB_01009 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNEBHBDB_01010 2.28e-29 - - - M - - - GBS Bsp-like repeat
KNEBHBDB_01011 4.14e-232 - - - M - - - GBS Bsp-like repeat
KNEBHBDB_01012 3.22e-156 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
KNEBHBDB_01013 9.19e-178 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KNEBHBDB_01014 4.38e-28 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KNEBHBDB_01015 3.48e-14 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KNEBHBDB_01016 2.27e-73 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KNEBHBDB_01017 5.34e-214 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KNEBHBDB_01018 1.45e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KNEBHBDB_01019 0.0 - - - P - - - ABC transporter transmembrane region
KNEBHBDB_01021 1.32e-195 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNEBHBDB_01022 1.6e-22 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNEBHBDB_01023 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KNEBHBDB_01024 1.02e-112 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNEBHBDB_01025 9.1e-77 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNEBHBDB_01026 8.44e-71 - - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNEBHBDB_01027 4.31e-236 - - - S - - - CRISPR-associated protein Csn2 subfamily St
KNEBHBDB_01028 3.27e-189 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
KNEBHBDB_01029 2.25e-101 XK27_03015 - - S ko:K07089 - ko00000 permease
KNEBHBDB_01030 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KNEBHBDB_01031 8.92e-116 pacL - - P - - - cation transport ATPase
KNEBHBDB_01032 1.76e-258 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KNEBHBDB_01033 3.46e-62 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KNEBHBDB_01034 3.05e-183 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KNEBHBDB_01036 3.79e-12 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
KNEBHBDB_01037 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNEBHBDB_01038 2.79e-06 clpP 3.4.21.92 - E ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNEBHBDB_01039 4.06e-53 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNEBHBDB_01040 1.05e-43 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNEBHBDB_01041 5.4e-147 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_01042 7.32e-175 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_01043 7.96e-11 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_01044 5.56e-37 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KNEBHBDB_01045 2.39e-190 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNEBHBDB_01046 4.86e-203 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNEBHBDB_01047 6.8e-46 yugF - - I - - - carboxylic ester hydrolase activity
KNEBHBDB_01048 9.87e-12 - - - - - - - -
KNEBHBDB_01049 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KNEBHBDB_01050 1.23e-101 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
KNEBHBDB_01052 1.68e-53 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01053 1.01e-76 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KNEBHBDB_01054 2.84e-108 - - - S - - - Pfam:DUF2276
KNEBHBDB_01055 6.26e-222 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
KNEBHBDB_01056 3e-34 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
KNEBHBDB_01057 5.6e-108 csm1 - - S ko:K07016 - ko00000,ko02048 CRISPR-associated protein Csm1 family
KNEBHBDB_01058 7.5e-83 - - - L ko:K19138 - ko00000,ko02048 Pfam:DUF310
KNEBHBDB_01059 1.62e-150 csm3 - - L ko:K09002 - ko00000,ko02048 RAMP superfamily
KNEBHBDB_01060 2.15e-206 csm4 - - L ko:K19139 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm4 family
KNEBHBDB_01061 6.15e-260 csm5 - - L ko:K19140 - ko00000,ko02048 CRISPR-associated RAMP protein, Csm5 family
KNEBHBDB_01062 4.49e-75 - - - S - - - Psort location Cytoplasmic, score
KNEBHBDB_01063 5.04e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KNEBHBDB_01064 2.93e-143 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNEBHBDB_01065 3.66e-11 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 amidase activity
KNEBHBDB_01066 3.14e-63 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KNEBHBDB_01067 5.13e-119 lemA - - S ko:K03744 - ko00000 LemA family
KNEBHBDB_01068 1.15e-87 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KNEBHBDB_01069 2.91e-87 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KNEBHBDB_01070 1.01e-95 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KNEBHBDB_01071 3.09e-73 - - - S - - - Domain of unknown function (DUF4430)
KNEBHBDB_01072 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KNEBHBDB_01073 4.34e-225 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KNEBHBDB_01074 3.3e-237 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KNEBHBDB_01075 5.54e-144 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KNEBHBDB_01076 1.17e-67 - - - V - - - D-alanyl-D-alanine carboxypeptidase
KNEBHBDB_01077 4.44e-204 - - - V - - - D-alanyl-D-alanine carboxypeptidase
KNEBHBDB_01078 1.36e-81 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KNEBHBDB_01079 1.07e-36 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
KNEBHBDB_01080 1.24e-104 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
KNEBHBDB_01081 1.33e-235 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
KNEBHBDB_01082 1.92e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KNEBHBDB_01083 2.76e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KNEBHBDB_01084 1.31e-209 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KNEBHBDB_01086 3.96e-99 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNEBHBDB_01087 1.02e-70 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNEBHBDB_01088 1.27e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNEBHBDB_01089 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNEBHBDB_01090 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KNEBHBDB_01091 7.49e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNEBHBDB_01092 4.51e-35 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
KNEBHBDB_01093 3.8e-43 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
KNEBHBDB_01094 5.27e-269 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KNEBHBDB_01095 5.38e-44 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KNEBHBDB_01096 3.96e-125 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNEBHBDB_01097 3.41e-96 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KNEBHBDB_01098 1.44e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KNEBHBDB_01100 3.75e-56 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
KNEBHBDB_01101 2.3e-72 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
KNEBHBDB_01104 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNEBHBDB_01105 8.92e-09 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNEBHBDB_01106 1.25e-123 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNEBHBDB_01107 1.56e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KNEBHBDB_01108 2.18e-150 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNEBHBDB_01109 1.87e-118 - - - K - - - acetyltransferase
KNEBHBDB_01110 7.68e-20 - - - - - - - -
KNEBHBDB_01111 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KNEBHBDB_01112 1.72e-300 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_01113 4.49e-33 yrzB - - S - - - Belongs to the UPF0473 family
KNEBHBDB_01114 1.61e-90 - - - F - - - NUDIX domain
KNEBHBDB_01115 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KNEBHBDB_01116 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KNEBHBDB_01117 1.02e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KNEBHBDB_01118 7.25e-137 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KNEBHBDB_01119 6.54e-96 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KNEBHBDB_01120 2.99e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
KNEBHBDB_01121 1.85e-82 manO - - S - - - protein conserved in bacteria
KNEBHBDB_01122 2.81e-307 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNEBHBDB_01123 7.89e-113 - - - S - - - Protein of unknown function DUF262
KNEBHBDB_01124 1.48e-90 - - - S - - - Protein of unknown function DUF262
KNEBHBDB_01126 9.92e-18 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_01139 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNEBHBDB_01140 1.19e-287 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNEBHBDB_01141 3.23e-81 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNEBHBDB_01142 1.43e-186 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KNEBHBDB_01143 6.87e-120 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KNEBHBDB_01144 1.5e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
KNEBHBDB_01145 7.88e-307 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
KNEBHBDB_01146 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KNEBHBDB_01147 1.13e-13 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-ascorbate 6-phosphate lactonase
KNEBHBDB_01148 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KNEBHBDB_01149 2.52e-83 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KNEBHBDB_01151 2.84e-285 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
KNEBHBDB_01152 2.09e-141 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
KNEBHBDB_01153 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KNEBHBDB_01154 6.73e-245 yfmL - - L - - - DEAD DEAH box helicase
KNEBHBDB_01155 5.79e-28 - 6.3.2.2, 6.3.2.4 - F ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 ko00000,ko00001,ko00002,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KNEBHBDB_01156 1.69e-86 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KNEBHBDB_01157 1.12e-178 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KNEBHBDB_01158 4.94e-69 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNEBHBDB_01159 2.77e-223 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNEBHBDB_01160 4.9e-134 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNEBHBDB_01161 8.44e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNEBHBDB_01163 4.1e-93 - - - L - - - Transposase (IS116 IS110 IS902 family)
KNEBHBDB_01164 2.47e-81 - - - L - - - Transposase (IS116 IS110 IS902 family)
KNEBHBDB_01166 2.77e-81 ypuA - - S - - - secreted protein
KNEBHBDB_01167 1.78e-143 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNEBHBDB_01168 2.92e-78 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNEBHBDB_01169 5.12e-35 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
KNEBHBDB_01170 2.83e-22 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KNEBHBDB_01171 5.86e-185 ylmH - - T ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 S4 RNA-binding domain
KNEBHBDB_01172 5.11e-187 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division protein DivIVA
KNEBHBDB_01173 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNEBHBDB_01174 1.49e-93 - - - S - - - Glycosyl transferase family 2
KNEBHBDB_01175 1.8e-148 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNEBHBDB_01176 2.68e-24 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNEBHBDB_01177 3.02e-312 - - - - - - - -
KNEBHBDB_01178 8.57e-218 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
KNEBHBDB_01179 1.58e-214 - - - M - - - Psort location CytoplasmicMembrane, score
KNEBHBDB_01180 2.97e-19 - - - M - - - Psort location CytoplasmicMembrane, score
KNEBHBDB_01181 2.37e-36 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPase activity
KNEBHBDB_01182 9.91e-218 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_01183 4.86e-259 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KNEBHBDB_01184 2.01e-213 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_01185 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_01186 3.62e-202 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KNEBHBDB_01187 1.66e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KNEBHBDB_01188 2.3e-66 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNEBHBDB_01189 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KNEBHBDB_01190 1.58e-100 ureE - - O ko:K03187 - ko00000 enzyme active site formation
KNEBHBDB_01191 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KNEBHBDB_01192 0.000903 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KNEBHBDB_01193 7.05e-106 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KNEBHBDB_01194 2.53e-206 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KNEBHBDB_01195 2.53e-51 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KNEBHBDB_01196 3.4e-136 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
KNEBHBDB_01197 9.05e-112 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
KNEBHBDB_01199 5.22e-141 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNEBHBDB_01200 6.15e-153 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNEBHBDB_01201 1.91e-242 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KNEBHBDB_01202 3.84e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNEBHBDB_01203 6.32e-103 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNEBHBDB_01204 2.53e-131 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNEBHBDB_01206 5.02e-173 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KNEBHBDB_01207 4.78e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KNEBHBDB_01209 3.39e-23 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KNEBHBDB_01210 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KNEBHBDB_01211 7.18e-133 XK27_01785 - - S - - - cog cog1284
KNEBHBDB_01212 9.49e-36 XK27_01785 - - S - - - cog cog1284
KNEBHBDB_01213 1.21e-109 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNEBHBDB_01214 2.24e-33 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNEBHBDB_01215 3.31e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
KNEBHBDB_01216 2.8e-44 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
KNEBHBDB_01217 2.92e-135 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
KNEBHBDB_01218 1.33e-77 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
KNEBHBDB_01219 1.22e-270 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KNEBHBDB_01220 1.33e-289 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNEBHBDB_01221 3.03e-108 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNEBHBDB_01222 7.8e-126 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNEBHBDB_01223 1.46e-118 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
KNEBHBDB_01224 1.09e-98 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 carboxypeptidase activity
KNEBHBDB_01226 6.94e-54 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_01227 1.27e-114 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_01228 8.54e-62 XK27_03570 - - S ko:K19784 - ko00000 reductase
KNEBHBDB_01229 1.13e-39 XK27_03570 - - S ko:K19784 - ko00000 reductase
KNEBHBDB_01230 4.14e-72 badR - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
KNEBHBDB_01231 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
KNEBHBDB_01232 1.25e-68 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNEBHBDB_01233 2.91e-59 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNEBHBDB_01234 2.84e-73 yabA - - L - - - Involved in initiation control of chromosome replication
KNEBHBDB_01235 7.96e-135 yaaT - - S - - - stage 0 sporulation protein
KNEBHBDB_01236 5.52e-207 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
KNEBHBDB_01237 5.91e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNEBHBDB_01238 6.58e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNEBHBDB_01239 4.41e-283 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNEBHBDB_01240 3.66e-246 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KNEBHBDB_01241 3.4e-24 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KNEBHBDB_01242 3.29e-60 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
KNEBHBDB_01244 4.55e-140 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KNEBHBDB_01245 4.75e-53 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KNEBHBDB_01246 2.35e-12 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KNEBHBDB_01247 2.18e-10 - - - - - - - -
KNEBHBDB_01248 5.93e-34 - - - - - - - -
KNEBHBDB_01249 5.72e-180 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNEBHBDB_01250 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KNEBHBDB_01251 8.71e-110 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
KNEBHBDB_01252 5.14e-105 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KNEBHBDB_01253 5.2e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KNEBHBDB_01254 7.42e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KNEBHBDB_01255 2.96e-106 - - - K - - - DNA-binding helix-turn-helix protein
KNEBHBDB_01256 7.1e-131 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNEBHBDB_01257 1.67e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNEBHBDB_01258 7.18e-170 - - - GK - - - ROK family
KNEBHBDB_01259 2.89e-162 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KNEBHBDB_01260 3.14e-30 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNEBHBDB_01261 1.79e-176 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNEBHBDB_01262 1.34e-34 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNEBHBDB_01263 1.47e-33 - - - - - - - -
KNEBHBDB_01264 1.5e-278 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KNEBHBDB_01265 5.05e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KNEBHBDB_01266 1.07e-179 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KNEBHBDB_01267 2.44e-39 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KNEBHBDB_01268 4.2e-144 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KNEBHBDB_01269 1.98e-35 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KNEBHBDB_01270 1.34e-235 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
KNEBHBDB_01271 2.03e-35 XK27_07735 - - S - - - YjbR
KNEBHBDB_01272 4.49e-183 XK27_07735 - - S - - - YjbR
KNEBHBDB_01273 4.66e-50 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KNEBHBDB_01274 1.68e-203 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KNEBHBDB_01275 5.45e-64 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KNEBHBDB_01276 5.67e-19 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KNEBHBDB_01277 8.99e-44 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KNEBHBDB_01278 1.6e-12 - - - M - - - transferase activity, transferring glycosyl groups
KNEBHBDB_01279 2.21e-45 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_01280 3.87e-201 tra981A - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
KNEBHBDB_01281 4.3e-158 - - - L ko:K07498 - ko00000 DDE domain
KNEBHBDB_01282 1.02e-43 - - - S - - - Glycosyltransferase like family 2
KNEBHBDB_01283 1.74e-91 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KNEBHBDB_01284 4.06e-54 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
KNEBHBDB_01285 1.2e-23 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
KNEBHBDB_01286 1.2e-66 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
KNEBHBDB_01287 1.09e-31 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
KNEBHBDB_01288 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KNEBHBDB_01289 4.72e-244 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNEBHBDB_01290 3.78e-45 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KNEBHBDB_01291 3.19e-166 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KNEBHBDB_01292 8.04e-06 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KNEBHBDB_01293 7.81e-117 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KNEBHBDB_01294 3.83e-35 - - - - - - - -
KNEBHBDB_01295 4.07e-32 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNEBHBDB_01296 2.2e-61 - - - L - - - transposase activity
KNEBHBDB_01297 3.55e-49 - - - L - - - transposition
KNEBHBDB_01298 2.02e-53 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_01299 1.01e-63 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_01300 2.7e-315 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_01301 1.46e-199 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
KNEBHBDB_01302 1.02e-46 - - - F ko:K09790 - ko00000 Protein of unknown function (DUF454)
KNEBHBDB_01303 1.28e-294 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
KNEBHBDB_01304 5.25e-129 XK27_00835 - - S - - - hydrolases of the HAD superfamily
KNEBHBDB_01305 3.49e-129 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNEBHBDB_01306 2.2e-173 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNEBHBDB_01307 2.68e-51 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNEBHBDB_01308 5.93e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KNEBHBDB_01309 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
KNEBHBDB_01310 2.59e-140 - - - S - - - Domain of unknown function (DUF1803)
KNEBHBDB_01311 9.83e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KNEBHBDB_01312 3.96e-179 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KNEBHBDB_01313 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNEBHBDB_01314 4.68e-148 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KNEBHBDB_01315 5.66e-86 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KNEBHBDB_01316 6.81e-85 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KNEBHBDB_01317 1.55e-35 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KNEBHBDB_01318 2.01e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01319 9.46e-200 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KNEBHBDB_01321 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KNEBHBDB_01322 7.86e-06 - - - S - - - Short repeat of unknown function (DUF308)
KNEBHBDB_01323 5.81e-81 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01324 9.09e-313 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01325 7.9e-288 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KNEBHBDB_01326 6.34e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KNEBHBDB_01327 1.13e-138 degV - - T - - - EDD domain protein, DegV family
KNEBHBDB_01328 5.79e-43 XK27_08360 - - S - - - lipid binding
KNEBHBDB_01329 5.9e-40 ypmB - - S - - - Protein conserved in bacteria
KNEBHBDB_01330 3.85e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KNEBHBDB_01331 8.88e-308 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KNEBHBDB_01335 7.35e-22 - - - L - - - Transposase
KNEBHBDB_01336 1.76e-87 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
KNEBHBDB_01337 7.13e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KNEBHBDB_01338 3.44e-112 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KNEBHBDB_01339 1.39e-17 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KNEBHBDB_01341 3.85e-88 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KNEBHBDB_01342 5.48e-123 - - - L - - - helicase
KNEBHBDB_01343 1.94e-157 - - - L - - - helicase
KNEBHBDB_01344 2.04e-284 - - - L - - - helicase
KNEBHBDB_01345 2.06e-132 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNEBHBDB_01346 5.84e-141 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
KNEBHBDB_01347 6.75e-48 hk02 - - T - - - signal transduction protein with a C-terminal ATPase domain
KNEBHBDB_01348 3.51e-170 rr02 - - KT - - - response regulator
KNEBHBDB_01349 2.9e-56 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KNEBHBDB_01350 3.27e-170 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KNEBHBDB_01351 2.86e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KNEBHBDB_01352 1.79e-157 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KNEBHBDB_01353 4.55e-159 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KNEBHBDB_01354 1.1e-90 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNEBHBDB_01355 4.16e-126 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KNEBHBDB_01356 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KNEBHBDB_01357 8.85e-125 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KNEBHBDB_01358 5.65e-99 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KNEBHBDB_01359 3.05e-31 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNEBHBDB_01360 1.47e-83 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KNEBHBDB_01361 2.66e-58 licT - - K ko:K02538,ko:K03488 - ko00000,ko03000 transcriptional antiterminator
KNEBHBDB_01362 8.82e-49 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNEBHBDB_01363 9.96e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KNEBHBDB_01364 2.35e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNEBHBDB_01365 9.11e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KNEBHBDB_01366 2.32e-23 - - - D - - - nuclear chromosome segregation
KNEBHBDB_01367 4.7e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KNEBHBDB_01368 5.26e-174 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KNEBHBDB_01369 7.47e-107 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KNEBHBDB_01370 1.58e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KNEBHBDB_01371 3.99e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNEBHBDB_01372 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNEBHBDB_01373 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNEBHBDB_01374 2.05e-41 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNEBHBDB_01375 1.44e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNEBHBDB_01376 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNEBHBDB_01377 9.94e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNEBHBDB_01378 2e-32 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
KNEBHBDB_01379 1.03e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KNEBHBDB_01380 1.37e-185 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNEBHBDB_01381 1.34e-72 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNEBHBDB_01382 3.66e-49 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNEBHBDB_01383 2.75e-51 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNEBHBDB_01384 1.45e-23 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNEBHBDB_01385 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNEBHBDB_01386 2.79e-111 ccl - - S - - - cog cog4708
KNEBHBDB_01387 2.38e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
KNEBHBDB_01388 1.52e-202 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KNEBHBDB_01389 9.5e-31 ytoI - - K - - - transcriptional regulator containing CBS domains
KNEBHBDB_01390 2.09e-118 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KNEBHBDB_01391 2.67e-115 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNEBHBDB_01392 6.46e-81 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
KNEBHBDB_01393 1.03e-206 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KNEBHBDB_01394 2.77e-45 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
KNEBHBDB_01395 1.13e-105 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNEBHBDB_01396 1.23e-58 - - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
KNEBHBDB_01397 2.72e-36 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
KNEBHBDB_01398 5.31e-30 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 protein secretion by the type I secretion system
KNEBHBDB_01399 1.34e-89 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KNEBHBDB_01400 2.08e-58 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01401 6.26e-29 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01402 1.39e-178 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
KNEBHBDB_01403 1.77e-228 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
KNEBHBDB_01405 1.82e-126 mraW1 - - J - - - (SAM)-dependent
KNEBHBDB_01406 1.03e-129 ytqA - - S ko:K07139 - ko00000 radical SAM protein
KNEBHBDB_01407 7.14e-25 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNEBHBDB_01408 3.7e-71 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KNEBHBDB_01409 2.93e-291 noxE - - P - - - NADH oxidase
KNEBHBDB_01410 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
KNEBHBDB_01412 1.28e-73 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNEBHBDB_01413 7.92e-142 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
KNEBHBDB_01415 1.08e-79 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KNEBHBDB_01416 6.17e-14 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
KNEBHBDB_01417 5.69e-275 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNEBHBDB_01418 2.41e-34 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KNEBHBDB_01419 6.14e-155 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KNEBHBDB_01420 4.9e-45 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KNEBHBDB_01421 1.9e-11 - - - NU - - - Type II secretory pathway pseudopilin
KNEBHBDB_01422 4.4e-23 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
KNEBHBDB_01423 3.21e-42 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
KNEBHBDB_01424 2.23e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KNEBHBDB_01425 5.98e-54 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KNEBHBDB_01426 1.24e-123 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KNEBHBDB_01427 2.16e-118 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
KNEBHBDB_01428 9.64e-191 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KNEBHBDB_01429 2.68e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_01430 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNEBHBDB_01431 3.57e-192 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
KNEBHBDB_01432 1.3e-82 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNEBHBDB_01433 8.23e-218 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNEBHBDB_01434 8.42e-55 WQ51_05770 - - KT - - - PspC domain
KNEBHBDB_01435 3.63e-113 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KNEBHBDB_01436 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
KNEBHBDB_01437 1.07e-42 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
KNEBHBDB_01438 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNEBHBDB_01439 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNEBHBDB_01440 9.64e-85 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KNEBHBDB_01441 1.4e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNEBHBDB_01442 1.36e-215 lysR - - K - - - transcriptional regulator (lysR family)
KNEBHBDB_01448 8.76e-183 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KNEBHBDB_01449 1.75e-41 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KNEBHBDB_01450 2.87e-43 salL 2.5.1.63, 2.5.1.94 - F ko:K09134,ko:K21153,ko:K22205 - ko00000,ko01000 Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KNEBHBDB_01451 5.4e-97 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
KNEBHBDB_01452 5.41e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KNEBHBDB_01453 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01454 4.37e-81 - - - KT - - - phosphorelay signal transduction system
KNEBHBDB_01455 5.67e-20 - - - S - - - Protein of unknown function (DUF3021)
KNEBHBDB_01456 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNEBHBDB_01457 3.69e-40 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KNEBHBDB_01458 1.2e-33 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KNEBHBDB_01459 5.08e-52 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KNEBHBDB_01460 7.25e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNEBHBDB_01461 9.33e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KNEBHBDB_01462 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KNEBHBDB_01463 1.32e-176 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
KNEBHBDB_01464 2.39e-164 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
KNEBHBDB_01465 1.16e-47 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KNEBHBDB_01466 1.03e-243 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KNEBHBDB_01467 2.71e-237 coiA - - S ko:K06198 - ko00000 Competence protein
KNEBHBDB_01468 3.83e-55 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KNEBHBDB_01469 1.14e-257 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KNEBHBDB_01471 6.48e-108 - - - L ko:K07485 - ko00000 Transposase
KNEBHBDB_01472 1.41e-35 - - - - - - - -
KNEBHBDB_01473 3.46e-64 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
KNEBHBDB_01474 4.57e-65 - - - S - - - CHY zinc finger
KNEBHBDB_01475 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KNEBHBDB_01476 1.7e-144 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KNEBHBDB_01477 2.26e-17 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KNEBHBDB_01479 1.66e-91 ytxH - - S - - - General stress protein
KNEBHBDB_01480 4.75e-20 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KNEBHBDB_01481 9.82e-16 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNEBHBDB_01482 5.5e-87 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KNEBHBDB_01483 2.98e-25 XK27_09115 - - M - - - LysM domain
KNEBHBDB_01484 1.12e-119 ebsA - - S - - - Family of unknown function (DUF5322)
KNEBHBDB_01485 5e-118 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KNEBHBDB_01486 4.9e-115 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KNEBHBDB_01487 9.3e-126 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KNEBHBDB_01488 4.79e-89 XK27_05225 - - G - - - COG0457 FOG TPR repeat
KNEBHBDB_01489 7.98e-98 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KNEBHBDB_01490 2.88e-99 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KNEBHBDB_01491 8.69e-158 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_01492 6.14e-165 - - - T - - - Histidine kinase
KNEBHBDB_01493 1.72e-85 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
KNEBHBDB_01494 1.48e-89 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
KNEBHBDB_01495 1.39e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
KNEBHBDB_01496 6.83e-227 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KNEBHBDB_01497 1.04e-181 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
KNEBHBDB_01498 2.05e-22 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
KNEBHBDB_01499 3.24e-54 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
KNEBHBDB_01500 3.26e-102 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
KNEBHBDB_01501 2.44e-149 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNEBHBDB_01502 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNEBHBDB_01503 3.96e-73 - 2.3.1.128, 5.2.1.8 - J ko:K03768,ko:K03790 - ko00000,ko01000,ko03009,ko03110 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNEBHBDB_01504 9.05e-61 - - - S - - - FMN binding
KNEBHBDB_01505 1.15e-65 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KNEBHBDB_01506 7.55e-64 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNEBHBDB_01507 4.08e-14 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNEBHBDB_01508 1.6e-106 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNEBHBDB_01512 1.31e-63 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
KNEBHBDB_01513 3.44e-142 blpT - - - - - - -
KNEBHBDB_01514 3.85e-27 - - - L - - - Transposase
KNEBHBDB_01515 3.91e-85 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KNEBHBDB_01516 7.35e-68 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KNEBHBDB_01517 1.23e-79 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KNEBHBDB_01518 3.46e-43 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KNEBHBDB_01519 1.44e-96 - - - L ko:K07497 - ko00000 integrase core domain
KNEBHBDB_01520 1.96e-47 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KNEBHBDB_01521 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KNEBHBDB_01522 1.31e-16 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KNEBHBDB_01523 1.73e-200 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KNEBHBDB_01524 1.4e-161 XK27_00020 - - J - - - Belongs to the SUA5 family
KNEBHBDB_01525 2.28e-18 XK27_00020 - - J - - - Belongs to the SUA5 family
KNEBHBDB_01526 6.32e-52 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNEBHBDB_01527 8.94e-26 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNEBHBDB_01528 2.19e-39 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_01529 5.99e-33 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNEBHBDB_01530 1.33e-60 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNEBHBDB_01531 1.23e-37 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNEBHBDB_01532 8.44e-27 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
KNEBHBDB_01533 6.6e-28 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
KNEBHBDB_01534 4.09e-207 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KNEBHBDB_01535 1.41e-38 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KNEBHBDB_01536 2.56e-36 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KNEBHBDB_01537 1.41e-76 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
KNEBHBDB_01538 3.64e-47 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KNEBHBDB_01539 2.32e-134 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KNEBHBDB_01540 1.19e-127 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KNEBHBDB_01541 2.06e-225 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNEBHBDB_01542 6.63e-231 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KNEBHBDB_01543 3.2e-98 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KNEBHBDB_01544 2.24e-185 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KNEBHBDB_01545 3.69e-188 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KNEBHBDB_01546 2.37e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
KNEBHBDB_01547 0.0 ydaO - - E - - - amino acid
KNEBHBDB_01548 5.83e-64 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KNEBHBDB_01549 1.39e-31 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KNEBHBDB_01550 9.38e-130 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KNEBHBDB_01551 4.73e-122 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KNEBHBDB_01552 3.61e-40 icaB - - G - - - deacetylase
KNEBHBDB_01553 3.81e-136 icaB - - G - - - deacetylase
KNEBHBDB_01554 2.07e-280 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KNEBHBDB_01555 5.58e-202 - - - - - - - -
KNEBHBDB_01557 1.71e-24 - - - IQ - - - PFAM AMP-dependent synthetase and ligase
KNEBHBDB_01558 1.75e-33 - - - E - - - LysE type translocator
KNEBHBDB_01559 7.18e-64 - - - E - - - LysE type translocator
KNEBHBDB_01560 7.19e-17 - - - - - - - -
KNEBHBDB_01561 2.07e-203 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNEBHBDB_01562 7.69e-96 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
KNEBHBDB_01563 2.39e-178 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
KNEBHBDB_01564 8.85e-42 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
KNEBHBDB_01565 1.35e-142 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
KNEBHBDB_01566 4.01e-95 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNEBHBDB_01567 1.9e-33 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
KNEBHBDB_01568 1.39e-100 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
KNEBHBDB_01569 3.29e-25 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KNEBHBDB_01570 1.41e-117 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KNEBHBDB_01571 8.93e-68 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KNEBHBDB_01572 8.74e-16 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KNEBHBDB_01573 1.89e-29 - 2.7.1.202 - GT ko:K02768,ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KNEBHBDB_01574 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KNEBHBDB_01575 1.47e-127 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KNEBHBDB_01576 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KNEBHBDB_01577 3.72e-16 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KNEBHBDB_01578 4.87e-74 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KNEBHBDB_01579 6.05e-197 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KNEBHBDB_01580 2.02e-26 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KNEBHBDB_01581 5.72e-212 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNEBHBDB_01582 1.05e-164 - - - K ko:K20374,ko:K21405 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KNEBHBDB_01583 6.06e-85 - - - KLT - - - serine threonine protein kinase
KNEBHBDB_01584 1.03e-213 XK27_12525 - - S - - - hmm pf01594
KNEBHBDB_01585 1.87e-36 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
KNEBHBDB_01586 7.45e-48 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KNEBHBDB_01587 5.67e-57 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
KNEBHBDB_01588 4.17e-50 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KNEBHBDB_01589 2.92e-51 - - - S - - - granule-associated protein
KNEBHBDB_01590 2.61e-219 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
KNEBHBDB_01591 4.39e-36 yeeD - - O ko:K07112 - ko00000 sulfur carrier activity
KNEBHBDB_01592 4.63e-63 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNEBHBDB_01593 6.33e-106 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KNEBHBDB_01596 1.81e-10 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNEBHBDB_01597 5.7e-31 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNEBHBDB_01598 6.53e-147 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNEBHBDB_01599 2.19e-17 - - - - - - - -
KNEBHBDB_01600 8.53e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNEBHBDB_01601 1.58e-160 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNEBHBDB_01603 3.92e-249 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KNEBHBDB_01604 7.01e-233 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNEBHBDB_01605 2.1e-47 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNEBHBDB_01606 4.5e-111 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KNEBHBDB_01608 5.66e-68 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
KNEBHBDB_01609 3.39e-40 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
KNEBHBDB_01610 2.87e-105 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
KNEBHBDB_01611 2.89e-173 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KNEBHBDB_01612 1.44e-106 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KNEBHBDB_01613 7.54e-36 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
KNEBHBDB_01614 4.94e-47 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
KNEBHBDB_01615 2.74e-47 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KNEBHBDB_01616 1.45e-09 ywnA_2 - - K - - - Transcriptional regulator
KNEBHBDB_01617 3.13e-142 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
KNEBHBDB_01618 5.56e-45 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNEBHBDB_01619 1.23e-34 - - - S - - - Protein of unknown function (DUF3114)
KNEBHBDB_01620 4.44e-127 - - - S - - - Protein of unknown function (DUF3114)
KNEBHBDB_01621 9.13e-121 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KNEBHBDB_01622 1.51e-27 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KNEBHBDB_01623 1.31e-84 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNEBHBDB_01624 1.69e-255 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNEBHBDB_01625 3.19e-110 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KNEBHBDB_01626 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KNEBHBDB_01628 1.43e-53 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KNEBHBDB_01629 4.7e-88 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KNEBHBDB_01630 5.02e-18 ilvD 4.2.1.9 - H ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Dehydratase family
KNEBHBDB_01631 2.28e-12 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KNEBHBDB_01632 1.52e-26 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KNEBHBDB_01633 4.49e-126 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KNEBHBDB_01634 1.84e-65 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KNEBHBDB_01635 2.62e-99 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
KNEBHBDB_01636 1.05e-212 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNEBHBDB_01637 7.53e-82 - - - M - - - Acetyltransferase (GNAT) domain
KNEBHBDB_01638 2.21e-10 - - - M - - - Acetyltransferase (GNAT) domain
KNEBHBDB_01639 3.26e-217 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KNEBHBDB_01640 6.79e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KNEBHBDB_01641 5.05e-140 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KNEBHBDB_01642 5.82e-82 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KNEBHBDB_01643 9.37e-31 mur1 - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 mannosyl-glycoprotein
KNEBHBDB_01644 9.69e-06 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KNEBHBDB_01645 3.32e-66 phoU_1 - - P ko:K03324 - ko00000,ko02000 sodium-dependent phosphate transmembrane transporter activity
KNEBHBDB_01646 3.97e-28 phoU_1 - - P ko:K03324 - ko00000,ko02000 sodium-dependent phosphate transmembrane transporter activity
KNEBHBDB_01647 1.56e-21 phoU_1 - - P ko:K03324 - ko00000,ko02000 sodium-dependent phosphate transmembrane transporter activity
KNEBHBDB_01648 2.9e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNEBHBDB_01649 1.03e-21 - - - - - - - -
KNEBHBDB_01650 2.18e-136 - - - L - - - Phage integrase family
KNEBHBDB_01651 1.36e-21 - - - - - - - -
KNEBHBDB_01652 4.23e-54 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
KNEBHBDB_01654 1.3e-306 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNEBHBDB_01655 4.29e-88 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KNEBHBDB_01656 5.96e-119 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KNEBHBDB_01657 2.13e-43 ysdA - - L - - - Membrane
KNEBHBDB_01658 3.77e-22 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNEBHBDB_01659 9.74e-16 leuC 4.2.1.33, 4.2.1.35 - H ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNEBHBDB_01660 1.67e-12 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
KNEBHBDB_01661 1.43e-96 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
KNEBHBDB_01662 2.83e-37 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
KNEBHBDB_01663 2.98e-119 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
KNEBHBDB_01664 7.51e-52 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
KNEBHBDB_01665 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNEBHBDB_01666 1.01e-71 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNEBHBDB_01667 8.99e-91 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KNEBHBDB_01668 1.24e-09 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNEBHBDB_01669 2.74e-64 yjbB - - G - - - Permeases of the major facilitator superfamily
KNEBHBDB_01670 6.43e-99 yjbB - - G - - - Permeases of the major facilitator superfamily
KNEBHBDB_01671 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNEBHBDB_01672 9.21e-25 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KNEBHBDB_01673 1.45e-159 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KNEBHBDB_01674 6.68e-90 sptS - - T - - - Histidine kinase
KNEBHBDB_01675 3.08e-24 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01676 2.32e-35 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01677 4.85e-104 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01678 5.19e-59 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01679 1.42e-47 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01680 1.73e-145 yeiH - - S - - - Membrane
KNEBHBDB_01681 8.42e-22 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
KNEBHBDB_01682 2.48e-106 mur1 - - NU ko:K02395 - ko00000,ko02035 amidase activity
KNEBHBDB_01683 7.55e-26 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_01684 5.8e-94 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_01685 4.37e-87 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KNEBHBDB_01686 1.27e-36 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KNEBHBDB_01687 9.97e-84 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KNEBHBDB_01688 2.12e-25 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KNEBHBDB_01689 8.9e-111 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNEBHBDB_01690 1.59e-75 - 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 PTS glucose transporter subunit IIA
KNEBHBDB_01691 6.19e-36 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01692 3.75e-62 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01693 6.05e-93 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01694 1.05e-33 - 2.7.1.208, 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNEBHBDB_01696 2.21e-46 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
KNEBHBDB_01697 1.7e-221 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KNEBHBDB_01698 5.19e-56 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KNEBHBDB_01699 2.49e-176 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01700 7.83e-47 - - - K - - - Acetyltransferase (GNAT) family
KNEBHBDB_01701 1.6e-25 sptS - - T - - - Histidine kinase
KNEBHBDB_01702 3.2e-29 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KNEBHBDB_01703 4.4e-101 - - - K - - - DNA-binding transcription factor activity
KNEBHBDB_01704 3.12e-39 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01705 2.55e-27 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01706 5.84e-138 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01707 5.69e-55 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01708 1.7e-45 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01709 1.01e-18 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01710 3.46e-31 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01711 6.86e-36 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01712 2.22e-98 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01713 6.36e-166 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
KNEBHBDB_01714 2.3e-27 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KNEBHBDB_01715 5.58e-74 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KNEBHBDB_01716 7.54e-108 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
KNEBHBDB_01717 1.09e-27 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
KNEBHBDB_01718 1.49e-80 rsmF - - J - - - NOL1 NOP2 sun family protein
KNEBHBDB_01719 2.31e-167 rsmF - - J - - - NOL1 NOP2 sun family protein
KNEBHBDB_01720 6.38e-16 rsmF - - J - - - NOL1 NOP2 sun family protein
KNEBHBDB_01721 3.97e-58 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KNEBHBDB_01722 3.58e-143 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KNEBHBDB_01723 1.51e-164 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KNEBHBDB_01724 1.3e-36 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNEBHBDB_01725 1.38e-53 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNEBHBDB_01728 2.3e-39 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KNEBHBDB_01729 2.64e-283 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KNEBHBDB_01730 1.29e-152 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNEBHBDB_01731 1.98e-146 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNEBHBDB_01732 1.27e-86 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KNEBHBDB_01733 1.22e-37 - - - M - - - LysM domain
KNEBHBDB_01734 8.26e-57 - - - M - - - LysM domain
KNEBHBDB_01735 3.41e-175 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KNEBHBDB_01736 1.36e-116 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KNEBHBDB_01737 1.07e-103 alkD - - L - - - Dna alkylation repair
KNEBHBDB_01738 3.23e-41 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
KNEBHBDB_01739 1.1e-41 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
KNEBHBDB_01740 3.81e-35 - - - K - - - hmm pf08876
KNEBHBDB_01741 6.58e-121 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KNEBHBDB_01742 8.27e-27 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KNEBHBDB_01743 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KNEBHBDB_01744 1.76e-164 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNEBHBDB_01745 1.88e-32 WQ51_03320 - - S - - - cog cog4835
KNEBHBDB_01748 1.24e-49 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_01749 1.34e-32 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
KNEBHBDB_01750 2.7e-51 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KNEBHBDB_01751 3.56e-68 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_01752 1.43e-112 - - - S - - - TraX protein
KNEBHBDB_01753 1.85e-66 - - - S - - - TraX protein
KNEBHBDB_01754 7.79e-237 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KNEBHBDB_01755 8.9e-175 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNEBHBDB_01756 1.42e-146 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
KNEBHBDB_01757 1.16e-26 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNEBHBDB_01758 3.48e-20 ybbR - - S - - - Protein conserved in bacteria
KNEBHBDB_01759 1.16e-180 ybbR - - S - - - Protein conserved in bacteria
KNEBHBDB_01760 3.05e-37 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
KNEBHBDB_01761 2.52e-63 acmA 3.2.1.17 - NU ko:K01185,ko:K02395 - ko00000,ko01000,ko02035 amidase activity
KNEBHBDB_01762 1.97e-113 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KNEBHBDB_01763 3.51e-293 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KNEBHBDB_01765 4.37e-12 XK27_05745 - - - - - - -
KNEBHBDB_01766 6.93e-38 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01767 1.44e-28 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01768 8.27e-34 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01769 4.85e-56 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01770 1.19e-47 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01771 9.85e-188 - 4.1.1.15 - E ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
KNEBHBDB_01772 2.82e-17 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KNEBHBDB_01773 4.18e-17 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KNEBHBDB_01774 4.07e-72 ytpP - - CO - - - Thioredoxin
KNEBHBDB_01775 1.13e-75 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNEBHBDB_01776 4.39e-57 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNEBHBDB_01777 1.67e-254 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KNEBHBDB_01778 0.000241 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 alanine dehydrogenase activity
KNEBHBDB_01779 4.71e-200 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
KNEBHBDB_01780 6.91e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KNEBHBDB_01781 4.2e-211 brpA - - K - - - Transcriptional
KNEBHBDB_01782 1.91e-119 - - - M - - - Acetyltransferase GNAT Family
KNEBHBDB_01783 7.61e-149 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNEBHBDB_01784 1.47e-31 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNEBHBDB_01785 3.05e-16 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNEBHBDB_01786 3.1e-49 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNEBHBDB_01787 7.71e-24 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KNEBHBDB_01788 4.99e-170 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KNEBHBDB_01790 2.1e-93 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
KNEBHBDB_01791 2.88e-33 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
KNEBHBDB_01792 6.16e-25 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KNEBHBDB_01793 2.77e-163 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
KNEBHBDB_01794 9.61e-197 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
KNEBHBDB_01795 7.02e-21 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNEBHBDB_01796 3.96e-33 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNEBHBDB_01797 1.83e-69 - - - S ko:K07025 - ko00000 phosphatase activity
KNEBHBDB_01798 1.49e-24 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
KNEBHBDB_01799 1.11e-42 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNEBHBDB_01800 4.48e-54 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
KNEBHBDB_01801 2.04e-62 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KNEBHBDB_01802 7.15e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01803 2.61e-120 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
KNEBHBDB_01804 1.58e-221 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KNEBHBDB_01805 2.51e-61 ylbG - - S - - - UPF0298 protein
KNEBHBDB_01806 6.07e-80 ylbF - - S - - - Belongs to the UPF0342 family
KNEBHBDB_01807 5.1e-64 usp 3.5.1.104, 3.5.1.28 CBM50 S ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 pathogenesis
KNEBHBDB_01808 3.39e-43 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KNEBHBDB_01809 2.93e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNEBHBDB_01810 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNEBHBDB_01811 4.49e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNEBHBDB_01812 1.41e-39 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNEBHBDB_01813 1.12e-32 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KNEBHBDB_01814 1.2e-207 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KNEBHBDB_01815 6.6e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KNEBHBDB_01816 7.42e-237 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNEBHBDB_01817 2.51e-62 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
KNEBHBDB_01818 5.52e-17 WQ51_02910 - - S - - - Protein of unknown function, DUF536
KNEBHBDB_01819 8.52e-63 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KNEBHBDB_01820 6.3e-18 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KNEBHBDB_01821 9.29e-45 - - - K - - - transcriptional regulator, MerR family
KNEBHBDB_01822 4.47e-74 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_01823 1.96e-209 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_01825 9.86e-117 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNEBHBDB_01826 2.03e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNEBHBDB_01828 2.8e-105 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNEBHBDB_01829 6.92e-137 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNEBHBDB_01830 1.79e-52 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNEBHBDB_01831 4.88e-95 - - - S - - - Haloacid dehalogenase-like hydrolase
KNEBHBDB_01832 3.47e-120 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KNEBHBDB_01833 1.35e-98 - - - EGP - - - Major facilitator Superfamily
KNEBHBDB_01834 1.09e-33 - - - KLT - - - serine threonine protein kinase
KNEBHBDB_01835 5.49e-44 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KNEBHBDB_01836 2.23e-52 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KNEBHBDB_01837 8.86e-107 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KNEBHBDB_01838 6.66e-48 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KNEBHBDB_01839 6.23e-75 yejC - - S - - - cyclic nucleotide-binding protein
KNEBHBDB_01840 1.48e-234 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
KNEBHBDB_01841 3.23e-170 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNEBHBDB_01842 1.83e-216 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
KNEBHBDB_01843 3.56e-53 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KNEBHBDB_01844 4.12e-52 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_01845 1.11e-30 - - - L ko:K07483 - ko00000 transposase activity
KNEBHBDB_01846 1.67e-37 - - - L ko:K07497 - ko00000 transposition
KNEBHBDB_01847 1.43e-90 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
KNEBHBDB_01848 1.37e-39 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KNEBHBDB_01849 1.86e-11 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KNEBHBDB_01852 3.19e-233 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KNEBHBDB_01853 6.7e-110 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
KNEBHBDB_01854 3.05e-45 XK27_00115 - - K - - - Acetyltransferase GNAT family
KNEBHBDB_01856 4.32e-29 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNEBHBDB_01857 9.17e-116 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KNEBHBDB_01858 4.71e-153 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNEBHBDB_01859 1.36e-14 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNEBHBDB_01860 5.73e-106 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNEBHBDB_01861 2.46e-42 - - - L ko:K07497 - ko00000 Integrase core domain protein
KNEBHBDB_01862 2.38e-67 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KNEBHBDB_01863 3.66e-90 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNEBHBDB_01864 6.03e-49 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KNEBHBDB_01865 8.15e-61 argR - - K ko:K03402 - ko00000,ko03000 arginine binding
KNEBHBDB_01866 9.67e-73 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KNEBHBDB_01867 3.07e-166 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KNEBHBDB_01868 5.32e-68 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_01869 9.07e-41 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_01870 3.31e-118 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_01871 4.14e-36 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_01872 1.47e-172 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNEBHBDB_01873 5.28e-56 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNEBHBDB_01874 3.59e-37 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
KNEBHBDB_01875 1.18e-20 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KNEBHBDB_01876 8.26e-14 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KNEBHBDB_01877 7.22e-48 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KNEBHBDB_01878 1.06e-32 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KNEBHBDB_01881 1.9e-27 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
KNEBHBDB_01882 6.19e-50 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KNEBHBDB_01883 2.49e-89 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KNEBHBDB_01884 8.52e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
KNEBHBDB_01885 4.28e-64 - - - G - - - Belongs to the phosphoglycerate mutase family
KNEBHBDB_01886 1.06e-23 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
KNEBHBDB_01887 1.17e-33 supH 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
KNEBHBDB_01888 1.17e-19 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KNEBHBDB_01889 1.07e-11 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KNEBHBDB_01890 9.64e-20 - - - M - - - transferase activity, transferring glycosyl groups
KNEBHBDB_01891 1.56e-48 - 4.1.1.15 - E ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
KNEBHBDB_01892 2.95e-58 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Psort location CytoplasmicMembrane, score 10.00
KNEBHBDB_01893 1.58e-30 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
KNEBHBDB_01894 2.32e-112 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
KNEBHBDB_01895 1.14e-56 ung2 - - L - - - Uracil-DNA glycosylase
KNEBHBDB_01896 3.88e-12 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
KNEBHBDB_01897 2.2e-191 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KNEBHBDB_01898 8.42e-63 WQ51_01275 - - S - - - DegV family
KNEBHBDB_01899 3.64e-136 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KNEBHBDB_01900 4.92e-106 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNEBHBDB_01901 2.57e-75 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNEBHBDB_01903 1.22e-97 - - - S - - - QueT transporter
KNEBHBDB_01904 2.26e-71 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNEBHBDB_01905 9.33e-44 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNEBHBDB_01906 2.35e-48 covS - - T - - - Histidine kinase
KNEBHBDB_01907 2.63e-44 - - - K - - - Cold shock protein domain
KNEBHBDB_01908 1.8e-46 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNEBHBDB_01909 4.51e-136 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KNEBHBDB_01910 1.1e-34 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNEBHBDB_01911 6.09e-68 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNEBHBDB_01912 3.73e-32 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KNEBHBDB_01913 6.71e-23 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNEBHBDB_01914 9.31e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KNEBHBDB_01915 1.11e-26 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
KNEBHBDB_01916 1.18e-107 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
KNEBHBDB_01917 1.67e-134 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNEBHBDB_01918 2.77e-11 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNEBHBDB_01919 5.08e-65 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KNEBHBDB_01920 1.25e-36 - - - S - - - Signal peptide protein, YSIRK family
KNEBHBDB_01921 2.66e-137 - - - K - - - Transcriptional regulator, TetR family
KNEBHBDB_01922 3.32e-190 cpsY - - K - - - Transcriptional regulator
KNEBHBDB_01923 5.54e-63 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KNEBHBDB_01924 3.49e-39 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KNEBHBDB_01925 3.74e-18 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KNEBHBDB_01926 1.45e-61 dtpT - - E ko:K03305 - ko00000 transporter
KNEBHBDB_01927 4.58e-52 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KNEBHBDB_01928 1.02e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KNEBHBDB_01929 3.16e-82 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KNEBHBDB_01930 1.41e-191 ytoI - - K - - - transcriptional regulator containing CBS domains
KNEBHBDB_01931 1.88e-69 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_01932 6.02e-82 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_01933 6.24e-36 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KNEBHBDB_01934 4.44e-159 XK27_05220 - - S - - - permease
KNEBHBDB_01935 2.48e-46 XK27_05225 - - G - - - COG0457 FOG TPR repeat
KNEBHBDB_01936 2.99e-60 XK27_05225 - - G - - - COG0457 FOG TPR repeat
KNEBHBDB_01937 7.48e-38 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KNEBHBDB_01938 1.06e-57 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KNEBHBDB_01939 2.36e-40 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KNEBHBDB_01940 4.44e-22 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KNEBHBDB_01941 1.76e-36 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNEBHBDB_01942 1.91e-152 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KNEBHBDB_01943 2.51e-27 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KNEBHBDB_01944 1.07e-82 yjqA - - S - - - Bacterial PH domain
KNEBHBDB_01945 1.4e-108 corA - - P - - - CorA-like protein
KNEBHBDB_01946 1.43e-167 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNEBHBDB_01947 8.7e-80 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
KNEBHBDB_01948 1.9e-77 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
KNEBHBDB_01949 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KNEBHBDB_01950 2.36e-19 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNEBHBDB_01951 7.76e-131 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNEBHBDB_01952 4.75e-40 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNEBHBDB_01953 1.47e-05 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNEBHBDB_01954 2.27e-197 ylbM - - S - - - Belongs to the UPF0348 family
KNEBHBDB_01955 1.95e-163 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNEBHBDB_01956 5.66e-138 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KNEBHBDB_01958 3.37e-41 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_01960 5.24e-139 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KNEBHBDB_01961 3.12e-23 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNEBHBDB_01962 6.68e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNEBHBDB_01963 7.58e-61 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNEBHBDB_01964 7.55e-53 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNEBHBDB_01965 1.14e-30 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KNEBHBDB_01966 5.53e-44 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
KNEBHBDB_01967 6.25e-83 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
KNEBHBDB_01968 3.47e-81 - - - S - - - Putative small multi-drug export protein
KNEBHBDB_01969 9.45e-88 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNEBHBDB_01970 3.16e-27 csbD - - K - - - CsbD-like
KNEBHBDB_01971 2.21e-23 - - - GK - - - ROK family
KNEBHBDB_01972 8.64e-121 - - - GK - - - ROK family
KNEBHBDB_01973 1.79e-222 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
KNEBHBDB_01974 3.56e-21 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
KNEBHBDB_01975 1.92e-75 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
KNEBHBDB_01976 3.3e-118 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNEBHBDB_01977 4.32e-14 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNEBHBDB_01978 7.17e-45 - - - S - - - cog cog4699
KNEBHBDB_01979 8.58e-78 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_01980 7.62e-137 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
KNEBHBDB_01981 1.18e-08 - - - - - - - -
KNEBHBDB_01982 3.33e-35 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KNEBHBDB_01983 5.09e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase F(0) sector subunit b
KNEBHBDB_01984 8.05e-93 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNEBHBDB_01986 2.18e-53 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KNEBHBDB_01987 6.02e-41 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
KNEBHBDB_01988 5.74e-36 ais - - G - - - alpha-ribazole phosphatase activity
KNEBHBDB_01989 4.91e-75 - - - - - - - -
KNEBHBDB_01990 1.1e-62 azlD - - E - - - branched-chain amino acid
KNEBHBDB_01991 2.28e-57 XK27_12120 - - E - - - AzlC protein
KNEBHBDB_01992 3.19e-97 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KNEBHBDB_01993 2.53e-140 - - - S - - - IA, variant 1
KNEBHBDB_01994 2.58e-100 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNEBHBDB_01995 4.24e-23 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KNEBHBDB_01996 1.04e-57 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_01997 8.96e-104 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KNEBHBDB_01998 1.99e-91 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KNEBHBDB_01999 2.06e-43 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KNEBHBDB_02000 6.22e-43 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KNEBHBDB_02001 2.37e-35 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNEBHBDB_02002 1.48e-31 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
KNEBHBDB_02003 5.12e-124 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KNEBHBDB_02004 7.84e-56 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNEBHBDB_02005 1.23e-49 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNEBHBDB_02006 3.1e-104 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
KNEBHBDB_02007 7.34e-31 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_02008 9.86e-64 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KNEBHBDB_02009 5.94e-35 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KNEBHBDB_02010 1.04e-81 - - - V - - - VanZ like family
KNEBHBDB_02011 1.87e-75 ypsA - - S - - - Belongs to the UPF0398 family
KNEBHBDB_02012 8.92e-82 XK27_02560 - - S - - - cog cog2151
KNEBHBDB_02013 1.22e-129 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KNEBHBDB_02015 1.18e-53 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNEBHBDB_02016 7.43e-25 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNEBHBDB_02017 3.39e-63 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNEBHBDB_02018 3.3e-47 yozE - - S - - - Belongs to the UPF0346 family
KNEBHBDB_02019 1.47e-80 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
KNEBHBDB_02020 9.42e-52 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNEBHBDB_02021 1.27e-45 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNEBHBDB_02022 1.22e-16 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNEBHBDB_02023 1.96e-116 - - - S - - - Phospholipase, patatin family
KNEBHBDB_02024 1.4e-76 - - - E - - - GDSL-like protein
KNEBHBDB_02025 2.62e-58 - - - - - - - -
KNEBHBDB_02026 1.96e-15 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
KNEBHBDB_02027 3.64e-34 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
KNEBHBDB_02028 1.2e-18 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_02029 5.48e-26 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNEBHBDB_02030 2.1e-32 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
KNEBHBDB_02031 2.76e-52 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KNEBHBDB_02032 6.21e-119 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KNEBHBDB_02033 7.9e-76 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KNEBHBDB_02034 8.86e-65 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_02035 1.91e-28 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNEBHBDB_02036 7.18e-136 XK27_07020 - - S - - - Belongs to the UPF0371 family
KNEBHBDB_02037 1.67e-62 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
KNEBHBDB_02038 7.83e-90 XK27_08050 - - O - - - stress-induced mitochondrial fusion
KNEBHBDB_02039 1.32e-23 XK27_07020 - - S - - - Belongs to the UPF0371 family
KNEBHBDB_02040 1.19e-53 XK27_07020 - - S - - - Belongs to the UPF0371 family
KNEBHBDB_02041 6.53e-77 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KNEBHBDB_02042 5.47e-29 - - - - - - - -
KNEBHBDB_02043 2.1e-18 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNEBHBDB_02044 2.73e-23 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
KNEBHBDB_02045 1.88e-77 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
KNEBHBDB_02046 5.95e-124 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KNEBHBDB_02047 2.58e-68 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
KNEBHBDB_02048 2.51e-26 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
KNEBHBDB_02049 1.31e-110 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
KNEBHBDB_02050 1.54e-89 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
KNEBHBDB_02051 3.23e-39 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
KNEBHBDB_02052 6.8e-33 - - - S ko:K06976 - ko00000 Domain of unknown function (DUF4081)
KNEBHBDB_02053 6.83e-135 dtpT - - E ko:K03305 - ko00000 transporter
KNEBHBDB_02054 4.64e-35 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
KNEBHBDB_02055 2.15e-36 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KNEBHBDB_02056 1.27e-18 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
KNEBHBDB_02057 2.18e-51 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
KNEBHBDB_02058 1.33e-116 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNEBHBDB_02059 5.45e-12 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KNEBHBDB_02060 9.25e-82 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
KNEBHBDB_02061 1.08e-152 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNEBHBDB_02063 2.11e-118 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KNEBHBDB_02064 1.22e-68 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_02065 2.07e-124 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNEBHBDB_02067 7.31e-16 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNEBHBDB_02068 1.92e-56 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
KNEBHBDB_02069 6.19e-48 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNEBHBDB_02070 3.09e-117 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNEBHBDB_02071 7.39e-37 - - - - - - - -
KNEBHBDB_02072 4.94e-75 - - - Q - - - phosphatase activity
KNEBHBDB_02073 3.22e-35 - - - S - - - haloacid dehalogenase-like hydrolase
KNEBHBDB_02075 4.13e-12 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
KNEBHBDB_02076 1.98e-81 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KNEBHBDB_02077 7.08e-23 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KNEBHBDB_02078 1.15e-61 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
KNEBHBDB_02079 1.77e-09 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
KNEBHBDB_02080 1.08e-28 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
KNEBHBDB_02081 1.88e-153 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNEBHBDB_02082 7.47e-59 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_02083 1.29e-56 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_02084 8.54e-167 XK27_02985 - - S - - - overlaps another CDS with the same product name
KNEBHBDB_02085 1.23e-20 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNEBHBDB_02086 1.63e-10 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KNEBHBDB_02087 1.56e-163 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNEBHBDB_02088 1.7e-59 yktA - - S - - - Belongs to the UPF0223 family
KNEBHBDB_02089 5.34e-150 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KNEBHBDB_02090 5.69e-24 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
KNEBHBDB_02091 8.69e-32 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
KNEBHBDB_02092 6.29e-23 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 effector of murein hydrolase
KNEBHBDB_02093 5.06e-83 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
KNEBHBDB_02094 2.99e-119 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KNEBHBDB_02095 4.34e-61 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KNEBHBDB_02096 3.97e-36 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
KNEBHBDB_02097 8.43e-60 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNEBHBDB_02098 8.3e-39 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)