ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
AKHFACLO_00001 1.73e-21 - - - L - - - Winged helix-turn helix
AKHFACLO_00002 1.26e-84 - - - - - - - -
AKHFACLO_00005 5.92e-59 tnp3521a2 - - L - - - Integrase core domain
AKHFACLO_00007 0.0 - - - S - - - Domain of unknown function (DUF5067)
AKHFACLO_00008 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
AKHFACLO_00009 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
AKHFACLO_00010 8.32e-168 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
AKHFACLO_00011 1.35e-156 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AKHFACLO_00012 3.59e-151 - - - - - - - -
AKHFACLO_00013 6.24e-145 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
AKHFACLO_00014 1.85e-285 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKHFACLO_00015 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AKHFACLO_00016 2.3e-233 - - - S - - - Protein conserved in bacteria
AKHFACLO_00018 1.5e-100 - - - S - - - Domain of unknown function (DUF4186)
AKHFACLO_00019 2.11e-221 dkgV - - C - - - Aldo/keto reductase family
AKHFACLO_00020 5.5e-199 - - - S - - - Aldo/keto reductase family
AKHFACLO_00021 2.5e-258 - - - K - - - WYL domain
AKHFACLO_00023 0.000413 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKHFACLO_00024 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
AKHFACLO_00025 1.9e-62 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
AKHFACLO_00026 1.4e-152 - - - S - - - zinc-ribbon domain
AKHFACLO_00027 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
AKHFACLO_00028 2.63e-52 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
AKHFACLO_00029 1.65e-245 - - - S - - - Domain of unknown function (DUF1963)
AKHFACLO_00030 2.53e-198 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKHFACLO_00031 1.5e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
AKHFACLO_00032 0.0 - - - I - - - acetylesterase activity
AKHFACLO_00033 8.04e-298 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AKHFACLO_00034 1.52e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
AKHFACLO_00035 4.48e-310 - - - NU - - - Tfp pilus assembly protein FimV
AKHFACLO_00037 3.79e-16 - - - L - - - PFAM Integrase catalytic
AKHFACLO_00038 9.38e-13 - - - - - - - -
AKHFACLO_00039 1.07e-115 - - - - - - - -
AKHFACLO_00041 2.72e-188 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
AKHFACLO_00042 1.38e-103 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AKHFACLO_00043 2.46e-279 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
AKHFACLO_00044 4.29e-203 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
AKHFACLO_00045 1.03e-292 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
AKHFACLO_00046 5.51e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKHFACLO_00047 2.62e-220 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
AKHFACLO_00048 1.25e-82 - - - - - - - -
AKHFACLO_00050 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKHFACLO_00051 6.77e-145 - - - - - - - -
AKHFACLO_00052 3.15e-236 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
AKHFACLO_00053 6.54e-41 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
AKHFACLO_00054 1.25e-75 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 Putative cell wall binding repeat
AKHFACLO_00055 9.1e-157 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AKHFACLO_00057 4.1e-237 - - - S - - - Membrane
AKHFACLO_00058 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
AKHFACLO_00059 3.23e-58 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
AKHFACLO_00060 1.32e-308 - - - EGP - - - Sugar (and other) transporter
AKHFACLO_00061 2.4e-296 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
AKHFACLO_00062 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
AKHFACLO_00063 1.2e-179 - - - K - - - DeoR C terminal sensor domain
AKHFACLO_00064 4.9e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
AKHFACLO_00065 1.05e-277 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
AKHFACLO_00066 2.09e-272 - - - - - - - -
AKHFACLO_00068 7.22e-262 - - - - - - - -
AKHFACLO_00070 2.62e-157 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
AKHFACLO_00071 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 Cation transporting ATPase, C-terminus
AKHFACLO_00072 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_00073 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00075 8.57e-222 - - - K - - - Putative sugar-binding domain
AKHFACLO_00076 1.68e-282 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
AKHFACLO_00077 0.0 - 2.7.1.53 - G ko:K00880 ko00040,ko00053,map00040,map00053 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
AKHFACLO_00078 3.64e-219 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
AKHFACLO_00079 1.39e-165 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Class II Aldolase and Adducin N-terminal domain
AKHFACLO_00080 2.33e-81 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AKHFACLO_00081 2e-199 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
AKHFACLO_00082 6.64e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKHFACLO_00083 2.19e-257 - - - K - - - helix_turn _helix lactose operon repressor
AKHFACLO_00084 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
AKHFACLO_00085 8.26e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AKHFACLO_00086 3.86e-142 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AKHFACLO_00089 3.04e-220 - - - G - - - Glycosyl hydrolases family 43
AKHFACLO_00090 1.09e-134 - - - G - - - Glycosyl hydrolases family 43
AKHFACLO_00091 9.81e-259 - - - K - - - helix_turn _helix lactose operon repressor
AKHFACLO_00093 5.17e-218 - - - S - - - Oxidoreductase, aldo keto reductase family protein
AKHFACLO_00094 3.43e-146 - - - L - - - Protein of unknown function (DUF1524)
AKHFACLO_00095 8.03e-295 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
AKHFACLO_00096 6.29e-134 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
AKHFACLO_00097 7.92e-230 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
AKHFACLO_00098 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
AKHFACLO_00099 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AKHFACLO_00100 5.94e-107 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AKHFACLO_00101 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
AKHFACLO_00102 1.54e-305 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
AKHFACLO_00103 2.24e-238 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AKHFACLO_00104 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
AKHFACLO_00105 3.18e-84 - - - - - - - -
AKHFACLO_00106 8.09e-76 - - - - - - - -
AKHFACLO_00107 9.19e-210 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_00108 0.0 - - - V - - - Efflux ABC transporter, permease protein
AKHFACLO_00109 9.55e-215 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
AKHFACLO_00110 4.92e-305 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
AKHFACLO_00112 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
AKHFACLO_00113 1.44e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
AKHFACLO_00114 2.12e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
AKHFACLO_00115 7.66e-275 - - - K - - - Psort location Cytoplasmic, score
AKHFACLO_00116 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKHFACLO_00117 2.13e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKHFACLO_00118 1.67e-293 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
AKHFACLO_00120 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AKHFACLO_00121 5.84e-160 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
AKHFACLO_00122 1.27e-221 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
AKHFACLO_00123 2.66e-225 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
AKHFACLO_00124 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
AKHFACLO_00125 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
AKHFACLO_00126 3.09e-252 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AKHFACLO_00127 4.85e-158 - - - - - - - -
AKHFACLO_00128 7.43e-256 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
AKHFACLO_00129 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
AKHFACLO_00130 3.55e-172 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
AKHFACLO_00131 4.56e-142 - - - - - - - -
AKHFACLO_00132 3.6e-243 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKHFACLO_00133 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AKHFACLO_00134 3.68e-152 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKHFACLO_00136 9.83e-37 - - - K - - - Winged helix DNA-binding domain
AKHFACLO_00137 1.97e-95 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
AKHFACLO_00138 7.71e-276 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AKHFACLO_00139 3.38e-54 - - - S - - - Protein of unknown function (DUF3046)
AKHFACLO_00140 2.53e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
AKHFACLO_00141 1.09e-122 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
AKHFACLO_00142 2.57e-154 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKHFACLO_00143 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
AKHFACLO_00144 1.56e-175 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
AKHFACLO_00145 2.54e-235 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AKHFACLO_00146 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AKHFACLO_00147 1.42e-156 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
AKHFACLO_00148 1.91e-219 - - - EG - - - EamA-like transporter family
AKHFACLO_00149 8.71e-176 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
AKHFACLO_00150 4.38e-151 - - - S - - - Domain of unknown function (DUF5067)
AKHFACLO_00151 0.0 - - - T - - - Histidine kinase
AKHFACLO_00152 6.09e-152 - - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_00153 0.0 - - - S - - - Protein of unknown function DUF262
AKHFACLO_00154 0.0 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
AKHFACLO_00155 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
AKHFACLO_00156 5.95e-305 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
AKHFACLO_00157 4.11e-150 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKHFACLO_00158 1.55e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKHFACLO_00160 5.92e-250 - - - EGP - - - Transmembrane secretion effector
AKHFACLO_00161 0.0 - - - S - - - Esterase-like activity of phytase
AKHFACLO_00162 5.83e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKHFACLO_00163 4.89e-166 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKHFACLO_00164 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKHFACLO_00165 9.4e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AKHFACLO_00166 1.16e-80 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKHFACLO_00168 1.28e-253 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
AKHFACLO_00169 1.8e-290 - - - M - - - Glycosyl transferase 4-like domain
AKHFACLO_00170 0.0 - - - M - - - Parallel beta-helix repeats
AKHFACLO_00171 1.64e-216 - - - M - - - Parallel beta-helix repeats
AKHFACLO_00172 1.91e-298 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AKHFACLO_00173 2.05e-177 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
AKHFACLO_00174 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
AKHFACLO_00175 7.3e-145 - - - - - - - -
AKHFACLO_00176 2.11e-138 - - - S - - - Protein of unknown function (DUF4230)
AKHFACLO_00177 7.71e-189 nnrE - - L - - - Uracil DNA glycosylase superfamily
AKHFACLO_00178 7.5e-43 - - - K - - - DNA-binding transcription factor activity
AKHFACLO_00179 5.5e-89 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AKHFACLO_00180 9.82e-45 - - - - - - - -
AKHFACLO_00181 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
AKHFACLO_00182 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AKHFACLO_00183 3.47e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
AKHFACLO_00184 5.35e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
AKHFACLO_00185 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
AKHFACLO_00186 0.0 - - - S - - - Putative esterase
AKHFACLO_00187 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
AKHFACLO_00189 9.5e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
AKHFACLO_00190 1.67e-174 - - - S - - - cobalamin synthesis protein
AKHFACLO_00191 4.39e-62 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
AKHFACLO_00192 4.85e-65 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKHFACLO_00193 1.79e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
AKHFACLO_00194 3.05e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
AKHFACLO_00195 6.34e-33 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
AKHFACLO_00196 8.73e-259 - - - S ko:K07089 - ko00000 Predicted permease
AKHFACLO_00197 3.19e-198 - - - S - - - TIGRFAM TIGR03943 family protein
AKHFACLO_00198 3.79e-61 - - - - - - - -
AKHFACLO_00199 4.79e-95 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
AKHFACLO_00200 8.53e-290 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AKHFACLO_00201 5.14e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AKHFACLO_00202 5.85e-228 yogA - - C - - - Zinc-binding dehydrogenase
AKHFACLO_00203 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKHFACLO_00205 1.06e-81 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKHFACLO_00206 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
AKHFACLO_00207 2.24e-139 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AKHFACLO_00208 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AKHFACLO_00209 8.33e-230 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
AKHFACLO_00210 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
AKHFACLO_00211 4.9e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
AKHFACLO_00213 5.44e-161 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
AKHFACLO_00214 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKHFACLO_00215 1.23e-155 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKHFACLO_00216 1.27e-219 - - - L - - - NIF3 (NGG1p interacting factor 3)
AKHFACLO_00217 1.02e-157 - - - L - - - NUDIX domain
AKHFACLO_00218 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
AKHFACLO_00219 1.19e-279 - - - - - - - -
AKHFACLO_00221 2.8e-169 - - - L - - - Phage integrase family
AKHFACLO_00222 2.42e-140 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
AKHFACLO_00223 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AKHFACLO_00224 1.39e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKHFACLO_00225 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
AKHFACLO_00229 1.7e-300 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
AKHFACLO_00230 0.0 - - - S - - - MvaI/BcnI restriction endonuclease family
AKHFACLO_00231 1.81e-39 - - - - - - - -
AKHFACLO_00232 6.2e-147 - - - - - - - -
AKHFACLO_00233 8.36e-18 gntR - - K - - - FCD
AKHFACLO_00234 2.76e-81 - - - L - - - protein secretion by the type IV secretion system
AKHFACLO_00236 1.32e-139 - - - S - - - Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A
AKHFACLO_00237 3.07e-55 - - - L - - - PFAM Integrase catalytic
AKHFACLO_00239 1.19e-181 - - - G - - - BNR repeat-like domain
AKHFACLO_00240 1.39e-233 xynB2 1.1.1.169 - E ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 lipolytic protein G-D-S-L family
AKHFACLO_00241 5.06e-115 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKHFACLO_00242 4.05e-51 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AKHFACLO_00243 0.0 - - - T - - - Forkhead associated domain
AKHFACLO_00244 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
AKHFACLO_00245 1.66e-55 - - - - - - - -
AKHFACLO_00246 4.95e-140 - - - NO - - - SAF
AKHFACLO_00247 1.88e-51 - - - S - - - Putative regulatory protein
AKHFACLO_00248 1.4e-154 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
AKHFACLO_00249 2.35e-119 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
AKHFACLO_00250 7.92e-260 - - - - - - - -
AKHFACLO_00251 3.49e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKHFACLO_00252 2.26e-166 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
AKHFACLO_00253 6.42e-57 yeaC - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
AKHFACLO_00257 2.71e-35 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
AKHFACLO_00258 4.5e-279 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
AKHFACLO_00259 3.55e-81 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
AKHFACLO_00260 1.16e-284 dapC - - E - - - Aminotransferase class I and II
AKHFACLO_00261 2.87e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKHFACLO_00263 0.0 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
AKHFACLO_00264 1.63e-146 yigZ - - S - - - Uncharacterized protein family UPF0029
AKHFACLO_00265 1.98e-153 - - - - - - - -
AKHFACLO_00266 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
AKHFACLO_00267 2.64e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKHFACLO_00268 1.71e-99 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
AKHFACLO_00269 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
AKHFACLO_00270 1.75e-297 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
AKHFACLO_00271 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
AKHFACLO_00272 1.36e-213 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
AKHFACLO_00273 4.27e-40 - - - S - - - YwiC-like protein
AKHFACLO_00274 5.3e-25 - - - S - - - YwiC-like protein
AKHFACLO_00275 5.42e-67 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
AKHFACLO_00276 6.65e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKHFACLO_00277 1.34e-154 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
AKHFACLO_00278 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AKHFACLO_00279 1.15e-196 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKHFACLO_00280 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKHFACLO_00281 2.21e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKHFACLO_00282 2.73e-161 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKHFACLO_00283 2.71e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKHFACLO_00284 6.77e-51 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
AKHFACLO_00285 9.4e-57 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKHFACLO_00286 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKHFACLO_00287 9.32e-70 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKHFACLO_00288 1.6e-133 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKHFACLO_00289 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKHFACLO_00290 9.65e-91 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKHFACLO_00291 2.69e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKHFACLO_00292 1.53e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKHFACLO_00293 2.04e-149 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKHFACLO_00294 1.46e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
AKHFACLO_00295 1.51e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
AKHFACLO_00296 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AKHFACLO_00297 4.79e-129 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AKHFACLO_00298 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKHFACLO_00299 1.03e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
AKHFACLO_00300 6.96e-83 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKHFACLO_00301 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKHFACLO_00302 1.4e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKHFACLO_00303 4.39e-94 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
AKHFACLO_00304 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
AKHFACLO_00305 4.08e-221 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AKHFACLO_00306 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
AKHFACLO_00307 5.51e-199 - - - E - - - Transglutaminase/protease-like homologues
AKHFACLO_00309 4.01e-48 tnp3503b - - L - - - Transposase and inactivated derivatives
AKHFACLO_00310 2.87e-221 - - - - - - - -
AKHFACLO_00311 1.16e-241 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
AKHFACLO_00312 4.77e-34 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKHFACLO_00313 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKHFACLO_00314 8.76e-124 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKHFACLO_00315 1.58e-299 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKHFACLO_00316 1.64e-300 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
AKHFACLO_00317 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AKHFACLO_00320 5.91e-179 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKHFACLO_00321 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
AKHFACLO_00322 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKHFACLO_00323 1.47e-56 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKHFACLO_00324 1.29e-259 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
AKHFACLO_00326 5.95e-05 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
AKHFACLO_00327 1.62e-131 - - - - - - - -
AKHFACLO_00330 1.21e-222 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
AKHFACLO_00331 2.8e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AKHFACLO_00332 6.69e-173 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AKHFACLO_00333 2.46e-315 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKHFACLO_00336 1.26e-118 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
AKHFACLO_00337 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
AKHFACLO_00338 3.14e-179 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AKHFACLO_00339 2.72e-34 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
AKHFACLO_00340 2.53e-146 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
AKHFACLO_00341 3.01e-184 - - - - - - - -
AKHFACLO_00342 4.42e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AKHFACLO_00343 1.04e-76 - - - S - - - Protein of unknown function (DUF3039)
AKHFACLO_00344 3.32e-247 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
AKHFACLO_00345 8.04e-203 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
AKHFACLO_00346 8.06e-175 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
AKHFACLO_00347 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
AKHFACLO_00348 2.09e-212 - - - P - - - Cation efflux family
AKHFACLO_00349 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKHFACLO_00350 7.8e-282 - - - S - - - Endonuclease/Exonuclease/phosphatase family
AKHFACLO_00351 1.36e-131 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
AKHFACLO_00352 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
AKHFACLO_00354 4.41e-77 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
AKHFACLO_00355 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
AKHFACLO_00356 3.22e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKHFACLO_00357 8.61e-227 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
AKHFACLO_00358 1.85e-108 - - - O - - - Hsp20/alpha crystallin family
AKHFACLO_00359 5.3e-137 - - - S ko:K07078 - ko00000 Nitroreductase family
AKHFACLO_00360 1.87e-156 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
AKHFACLO_00361 0.0 - - - U ko:K06956 - ko00000 Sodium:dicarboxylate symporter family
AKHFACLO_00362 0.0 - - - - - - - -
AKHFACLO_00365 2.88e-277 steT - - E ko:K03294 - ko00000 amino acid
AKHFACLO_00366 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
AKHFACLO_00367 7.42e-41 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
AKHFACLO_00368 2.69e-256 - - - G - - - pfkB family carbohydrate kinase
AKHFACLO_00370 1.23e-308 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
AKHFACLO_00371 8.3e-171 - - - K - - - helix_turn_helix, mercury resistance
AKHFACLO_00372 6.7e-78 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
AKHFACLO_00373 2.07e-71 - - - L - - - RelB antitoxin
AKHFACLO_00374 1.2e-300 - - - K - - - Helix-turn-helix XRE-family like proteins
AKHFACLO_00375 6.29e-162 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
AKHFACLO_00380 0.00013 - - - TV ko:K05792 - ko00000 HNH endonuclease
AKHFACLO_00381 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
AKHFACLO_00382 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AKHFACLO_00383 3.51e-27 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
AKHFACLO_00384 1.98e-203 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
AKHFACLO_00385 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
AKHFACLO_00386 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
AKHFACLO_00388 1.56e-177 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
AKHFACLO_00389 1.29e-233 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKHFACLO_00390 3.86e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
AKHFACLO_00391 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKHFACLO_00392 7.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKHFACLO_00393 9.87e-70 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AKHFACLO_00394 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
AKHFACLO_00395 2.59e-212 - - - S - - - Protein conserved in bacteria
AKHFACLO_00397 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKHFACLO_00398 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
AKHFACLO_00399 4.03e-143 - - - - - - - -
AKHFACLO_00400 7.89e-315 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKHFACLO_00401 5.36e-172 - - - S - - - Protein of unknown function (DUF3159)
AKHFACLO_00402 2.66e-196 - - - S - - - Protein of unknown function (DUF3710)
AKHFACLO_00403 2.02e-215 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
AKHFACLO_00404 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
AKHFACLO_00405 4.17e-186 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
AKHFACLO_00406 5.39e-296 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
AKHFACLO_00407 1.12e-109 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AKHFACLO_00408 1.34e-184 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
AKHFACLO_00409 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
AKHFACLO_00410 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
AKHFACLO_00411 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
AKHFACLO_00412 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
AKHFACLO_00414 2.19e-223 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKHFACLO_00415 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
AKHFACLO_00416 3.17e-199 - - - - - - - -
AKHFACLO_00417 1.1e-231 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
AKHFACLO_00418 3.75e-310 - - - M - - - LPXTG-motif cell wall anchor domain protein
AKHFACLO_00419 0.0 - - - S - - - LPXTG-motif cell wall anchor domain protein
AKHFACLO_00420 1.14e-134 - - - L - - - Helix-turn-helix domain
AKHFACLO_00421 2.18e-269 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AKHFACLO_00422 1.68e-223 - - - K - - - Psort location Cytoplasmic, score
AKHFACLO_00423 0.0 - - - KLT - - - Protein tyrosine kinase
AKHFACLO_00424 2.59e-201 - - - O - - - Thioredoxin
AKHFACLO_00426 4.1e-278 rpfB - - S ko:K21688 - ko00000 G5
AKHFACLO_00427 8.92e-218 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AKHFACLO_00428 1.08e-212 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AKHFACLO_00429 6.94e-146 - - - S - - - LytR cell envelope-related transcriptional attenuator
AKHFACLO_00430 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
AKHFACLO_00431 3.18e-160 mutT4 - - L - - - Belongs to the Nudix hydrolase family
AKHFACLO_00432 0.0 - - - M - - - Conserved repeat domain
AKHFACLO_00433 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
AKHFACLO_00434 1.95e-258 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AKHFACLO_00435 1.14e-311 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
AKHFACLO_00436 1.05e-229 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
AKHFACLO_00437 7.42e-162 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
AKHFACLO_00438 4.15e-120 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
AKHFACLO_00439 3.33e-79 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
AKHFACLO_00440 2.73e-107 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
AKHFACLO_00441 3.88e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
AKHFACLO_00442 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKHFACLO_00443 1.15e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AKHFACLO_00444 1.95e-308 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKHFACLO_00445 6.47e-124 - - - S - - - Protein of unknown function (DUF721)
AKHFACLO_00446 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKHFACLO_00447 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKHFACLO_00448 1.26e-230 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKHFACLO_00449 5.84e-104 - - - S - - - Transmembrane domain of unknown function (DUF3566)
AKHFACLO_00451 4.34e-240 - - - G - - - Glycosyl hydrolases family 43
AKHFACLO_00452 3.79e-239 - - - K - - - Periplasmic binding protein domain
AKHFACLO_00453 1.53e-289 - - - I - - - Serine aminopeptidase, S33
AKHFACLO_00455 1.32e-68 - - - S - - - Protein of unknown function (DUF2469)
AKHFACLO_00456 1.38e-251 - - - J - - - Acetyltransferase (GNAT) domain
AKHFACLO_00457 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKHFACLO_00458 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AKHFACLO_00459 3.33e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKHFACLO_00461 2.03e-81 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
AKHFACLO_00462 3.77e-81 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
AKHFACLO_00463 1.94e-213 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
AKHFACLO_00464 4.99e-164 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AKHFACLO_00465 2.93e-297 rmuC - - S ko:K09760 - ko00000 RmuC family
AKHFACLO_00466 6.68e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
AKHFACLO_00467 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
AKHFACLO_00468 0.0 - - - S ko:K03688 - ko00000 ABC1 family
AKHFACLO_00469 3.15e-44 - - - S - - - granule-associated protein
AKHFACLO_00470 1.02e-181 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
AKHFACLO_00471 0.0 murE - - M - - - Domain of unknown function (DUF1727)
AKHFACLO_00472 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
AKHFACLO_00473 0.0 dinF - - V - - - MatE
AKHFACLO_00474 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
AKHFACLO_00475 2.56e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
AKHFACLO_00476 2.1e-305 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
AKHFACLO_00477 1.06e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKHFACLO_00479 1.17e-172 icaR - - K - - - Bacterial regulatory proteins, tetR family
AKHFACLO_00480 1.96e-254 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
AKHFACLO_00481 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
AKHFACLO_00482 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
AKHFACLO_00484 8.22e-25 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
AKHFACLO_00485 1.99e-89 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
AKHFACLO_00486 8.19e-107 - - - - - - - -
AKHFACLO_00487 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
AKHFACLO_00488 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_00489 1.88e-105 - - - K - - - Winged helix DNA-binding domain
AKHFACLO_00491 0.0 - - - M - - - LPXTG cell wall anchor motif
AKHFACLO_00492 0.0 - - - M ko:K20276 ko02024,map02024 ko00000,ko00001 chlorophyll binding
AKHFACLO_00493 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat
AKHFACLO_00494 1.42e-172 - - - S - - - HAD hydrolase, family IA, variant 3
AKHFACLO_00496 2.13e-161 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
AKHFACLO_00497 2.44e-216 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKHFACLO_00498 1.6e-83 - - - - - - - -
AKHFACLO_00499 7.68e-170 - - - - - - - -
AKHFACLO_00500 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKHFACLO_00501 3.47e-110 - - - K - - - Transcriptional regulator
AKHFACLO_00502 1.89e-08 - - - G ko:K02027,ko:K10188 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
AKHFACLO_00503 3.47e-50 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
AKHFACLO_00504 1.63e-264 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
AKHFACLO_00505 3.58e-20 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
AKHFACLO_00506 5.49e-237 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
AKHFACLO_00507 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
AKHFACLO_00509 3.34e-211 - - - S - - - Glutamine amidotransferase domain
AKHFACLO_00510 1.9e-175 - - - T ko:K06950 - ko00000 HD domain
AKHFACLO_00511 5.74e-263 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
AKHFACLO_00512 0.0 - - - V - - - ABC transporter permease
AKHFACLO_00513 0.0 - - - H - - - Protein of unknown function (DUF4012)
AKHFACLO_00514 3.21e-191 - - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
AKHFACLO_00515 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_00516 1.12e-210 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
AKHFACLO_00517 2.41e-37 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
AKHFACLO_00518 0.0 - - - - - - - -
AKHFACLO_00519 4.05e-268 - - - S - - - Glycosyltransferase, group 2 family protein
AKHFACLO_00520 5.26e-38 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AKHFACLO_00521 2.97e-60 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
AKHFACLO_00522 3.04e-129 - - - - - - - -
AKHFACLO_00523 5.71e-257 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
AKHFACLO_00524 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AKHFACLO_00526 1.34e-196 - - - D - - - bacterial-type flagellum organization
AKHFACLO_00527 6.74e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
AKHFACLO_00528 3.56e-155 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
AKHFACLO_00530 1.3e-20 - - - NU - - - Type II secretion system (T2SS), protein F
AKHFACLO_00531 1.13e-54 - - - S - - - Protein of unknown function (DUF4244)
AKHFACLO_00532 3.62e-73 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
AKHFACLO_00533 1.61e-274 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
AKHFACLO_00534 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
AKHFACLO_00535 1.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKHFACLO_00536 2.68e-175 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
AKHFACLO_00537 2.36e-125 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
AKHFACLO_00539 7.59e-269 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKHFACLO_00540 1.77e-148 - - - - - - - -
AKHFACLO_00541 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
AKHFACLO_00542 3.11e-19 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
AKHFACLO_00543 0.0 - - - S - - - Calcineurin-like phosphoesterase
AKHFACLO_00544 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKHFACLO_00545 0.0 pbp5 - - M - - - Transglycosylase
AKHFACLO_00546 2.99e-294 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
AKHFACLO_00547 6.37e-179 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
AKHFACLO_00548 0.0 - - - M - - - PA domain
AKHFACLO_00549 3.23e-251 - - - I - - - PAP2 superfamily
AKHFACLO_00550 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKHFACLO_00551 4.2e-158 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKHFACLO_00552 2.02e-270 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
AKHFACLO_00553 7.71e-255 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AKHFACLO_00554 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
AKHFACLO_00555 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKHFACLO_00556 2.97e-157 - - - S - - - Fic/DOC family
AKHFACLO_00557 8.31e-256 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AKHFACLO_00558 8.33e-31 - - - G - - - MFS/sugar transport protein
AKHFACLO_00559 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
AKHFACLO_00560 2.38e-150 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
AKHFACLO_00561 3.04e-296 - - - S - - - Predicted membrane protein (DUF2318)
AKHFACLO_00562 3.23e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
AKHFACLO_00563 3.29e-281 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
AKHFACLO_00564 1.1e-190 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_00565 8.08e-103 - - - S - - - FMN_bind
AKHFACLO_00566 1.5e-167 - - - K ko:K03489,ko:K03710 - ko00000,ko03000 UTRA
AKHFACLO_00567 3.37e-88 - - - S - - - haloacid dehalogenase-like hydrolase
AKHFACLO_00568 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKHFACLO_00569 1.2e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
AKHFACLO_00570 1.29e-66 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
AKHFACLO_00571 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
AKHFACLO_00572 3.65e-44 - - - Q - - - phosphatase activity
AKHFACLO_00573 3.18e-103 - - - - - - - -
AKHFACLO_00574 1.13e-307 - - - S - - - Putative ABC-transporter type IV
AKHFACLO_00575 3.89e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
AKHFACLO_00578 7.68e-227 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
AKHFACLO_00579 4.4e-246 - - - M - - - Glycosyltransferase like family 2
AKHFACLO_00580 0.0 - - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
AKHFACLO_00581 0.0 - - - S - - - Tetratricopeptide repeat
AKHFACLO_00582 2.18e-266 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_00583 5.96e-167 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
AKHFACLO_00584 1.48e-214 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AKHFACLO_00585 1.32e-131 - - - L - - - Transposase, Mutator family
AKHFACLO_00586 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
AKHFACLO_00587 2.65e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AKHFACLO_00588 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
AKHFACLO_00589 5.73e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00590 1.75e-208 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00591 1.38e-183 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
AKHFACLO_00592 1.57e-199 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_00593 2.08e-239 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKHFACLO_00595 2.72e-111 - - - Q - - - Acetyltransferase (GNAT) domain
AKHFACLO_00596 2.16e-199 - - - I - - - Serine aminopeptidase, S33
AKHFACLO_00597 1.75e-69 - - - S - - - Putative heavy-metal-binding
AKHFACLO_00598 1.71e-58 - - - D - - - DivIVA domain protein
AKHFACLO_00599 3.19e-117 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
AKHFACLO_00600 0.0 - - - KL - - - Domain of unknown function (DUF3427)
AKHFACLO_00602 2.37e-250 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKHFACLO_00604 4.72e-147 - - - - - - - -
AKHFACLO_00605 2.55e-213 - - - EG - - - EamA-like transporter family
AKHFACLO_00606 3.88e-263 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
AKHFACLO_00607 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
AKHFACLO_00608 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
AKHFACLO_00609 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
AKHFACLO_00610 3.69e-167 fhaA - - T - - - Protein of unknown function (DUF2662)
AKHFACLO_00611 1.44e-122 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
AKHFACLO_00612 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
AKHFACLO_00613 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
AKHFACLO_00614 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
AKHFACLO_00615 5.69e-234 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
AKHFACLO_00616 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
AKHFACLO_00617 9.5e-156 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
AKHFACLO_00618 5.65e-296 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
AKHFACLO_00619 2.05e-183 - - - S - - - Bacterial protein of unknown function (DUF881)
AKHFACLO_00620 1.77e-93 crgA - - D - - - Involved in cell division
AKHFACLO_00621 0.0 - - - L - - - ribosomal rna small subunit methyltransferase
AKHFACLO_00623 1.19e-186 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
AKHFACLO_00624 7.68e-47 - - - - - - - -
AKHFACLO_00626 5.42e-33 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AKHFACLO_00627 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AKHFACLO_00628 5.53e-96 - - - I - - - Sterol carrier protein
AKHFACLO_00629 2.19e-60 - - - L ko:K07485 - ko00000 Transposase
AKHFACLO_00630 1.6e-69 istB - - L - - - IstB-like ATP binding protein
AKHFACLO_00631 1.21e-57 - - - L - - - Integrase core domain
AKHFACLO_00632 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
AKHFACLO_00633 3.8e-34 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
AKHFACLO_00634 1.9e-17 - - - - - - - -
AKHFACLO_00635 9.28e-77 yccF - - S - - - Inner membrane component domain
AKHFACLO_00636 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
AKHFACLO_00637 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKHFACLO_00638 2.55e-122 - - - T - - - Forkhead associated domain
AKHFACLO_00639 1.47e-101 - - - B - - - Belongs to the OprB family
AKHFACLO_00640 3.89e-210 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
AKHFACLO_00641 0.0 - - - E - - - Transglutaminase-like superfamily
AKHFACLO_00642 1.92e-300 - - - S - - - Protein of unknown function DUF58
AKHFACLO_00643 0.0 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
AKHFACLO_00644 0.0 - - - S - - - Fibronectin type 3 domain
AKHFACLO_00645 0.0 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
AKHFACLO_00646 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
AKHFACLO_00647 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
AKHFACLO_00648 6.85e-195 - - - K - - - -acetyltransferase
AKHFACLO_00649 0.0 - - - G - - - Major Facilitator Superfamily
AKHFACLO_00650 8.15e-23 - - - P ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AKHFACLO_00651 3.22e-33 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
AKHFACLO_00652 1.45e-76 - - - L - - - Transposase
AKHFACLO_00653 2.35e-169 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AKHFACLO_00654 6.97e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKHFACLO_00655 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKHFACLO_00656 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
AKHFACLO_00657 4.17e-308 vpr - - O - - - Subtilase family
AKHFACLO_00658 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKHFACLO_00659 1.58e-160 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AKHFACLO_00660 0.0 - - - S - - - zinc finger
AKHFACLO_00661 2.67e-139 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
AKHFACLO_00662 6.29e-292 aspB 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class-V
AKHFACLO_00663 2.46e-192 - - - L - - - PFAM Integrase catalytic
AKHFACLO_00664 0.0 - - - S - - - Protein of unknown function DUF262
AKHFACLO_00665 5.4e-39 - - - - - - - -
AKHFACLO_00666 3.32e-55 - - - E - - - Rard protein
AKHFACLO_00667 2.72e-40 - - - E - - - Rard protein
AKHFACLO_00668 1.62e-227 - - - I - - - alpha/beta hydrolase fold
AKHFACLO_00669 6.99e-266 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AKHFACLO_00670 2.04e-129 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
AKHFACLO_00671 2.44e-309 - - - L - - - Phage integrase, N-terminal SAM-like domain
AKHFACLO_00672 7.01e-31 - - - - - - - -
AKHFACLO_00673 2.51e-45 - - - - - - - -
AKHFACLO_00674 1.91e-297 - - - S - - - Protein of unknown function DUF262
AKHFACLO_00675 2.1e-63 - - - - - - - -
AKHFACLO_00676 7.91e-132 - - - S - - - Virulence protein RhuM family
AKHFACLO_00677 2.38e-157 - - - S - - - Domain of unknown function DUF1829
AKHFACLO_00679 9.62e-72 - - - - - - - -
AKHFACLO_00680 3.33e-47 - - - - - - - -
AKHFACLO_00681 2.11e-62 - - - - - - - -
AKHFACLO_00682 2.62e-169 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
AKHFACLO_00687 6.36e-50 - - - - - - - -
AKHFACLO_00689 1.66e-48 - - - - - - - -
AKHFACLO_00691 5.85e-115 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
AKHFACLO_00692 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
AKHFACLO_00693 1.11e-153 - - - K - - - Transcriptional regulator
AKHFACLO_00694 5.32e-36 - - - - - - - -
AKHFACLO_00695 2.96e-104 - - - V - - - HNH endonuclease
AKHFACLO_00696 1.04e-137 - - - A ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
AKHFACLO_00698 8.37e-66 - - - - - - - -
AKHFACLO_00700 1.83e-172 - - - - - - - -
AKHFACLO_00701 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AKHFACLO_00702 1.06e-260 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
AKHFACLO_00703 7.44e-151 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
AKHFACLO_00704 4.51e-79 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
AKHFACLO_00705 6.93e-236 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AKHFACLO_00706 1.17e-246 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKHFACLO_00707 1.85e-48 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
AKHFACLO_00709 4.61e-250 - - - K ko:K13633 - ko00000,ko03000 helix_turn_helix, arabinose operon control protein
AKHFACLO_00710 2.74e-209 - - - G ko:K05340 - ko00000,ko02000 Sugar transport protein
AKHFACLO_00711 1.16e-240 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
AKHFACLO_00712 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
AKHFACLO_00713 7.2e-144 - - - - - - - -
AKHFACLO_00714 9.28e-218 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
AKHFACLO_00715 9.71e-190 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
AKHFACLO_00716 0.0 - - - JKL - - - helicase superfamily c-terminal domain
AKHFACLO_00717 1.23e-210 - - - EG - - - EamA-like transporter family
AKHFACLO_00718 3.54e-187 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
AKHFACLO_00719 1.43e-188 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
AKHFACLO_00721 3.31e-39 - - - L - - - Transposase
AKHFACLO_00722 1.05e-271 - - - S - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_00723 0.0 - 2.5.1.49 - H ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.98
AKHFACLO_00724 4.57e-47 - - - C - - - Aldo/keto reductase family
AKHFACLO_00725 6.75e-95 - - - EGP - - - Major facilitator superfamily
AKHFACLO_00726 3.68e-229 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
AKHFACLO_00727 0.0 - - - S - - - ATPases associated with a variety of cellular activities
AKHFACLO_00728 7.83e-73 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
AKHFACLO_00729 1.7e-200 - - - I - - - alpha/beta hydrolase fold
AKHFACLO_00730 7.51e-145 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
AKHFACLO_00732 8.87e-66 - - - S - - - DUF218 domain
AKHFACLO_00733 1.43e-52 - - - S - - - Protein of unknown function (DUF979)
AKHFACLO_00734 4.32e-148 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AKHFACLO_00735 1.76e-161 - - - - - - - -
AKHFACLO_00736 1.34e-73 - - - M - - - domain, Protein
AKHFACLO_00737 8.64e-24 - - - M - - - domain, Protein
AKHFACLO_00738 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
AKHFACLO_00739 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 hydrolase family 20, catalytic
AKHFACLO_00740 1.88e-219 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
AKHFACLO_00741 9.56e-107 - - - S - - - Protein of unknown function (DUF3180)
AKHFACLO_00742 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKHFACLO_00743 1.12e-210 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKHFACLO_00744 2.05e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
AKHFACLO_00745 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKHFACLO_00746 2.65e-127 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
AKHFACLO_00747 6.03e-270 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AKHFACLO_00748 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
AKHFACLO_00749 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
AKHFACLO_00750 2.26e-215 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_00751 4.63e-294 - - - M - - - Glycosyl transferase family 21
AKHFACLO_00752 0.0 - - - S - - - AI-2E family transporter
AKHFACLO_00753 5.42e-227 - - - M - - - Glycosyltransferase like family 2
AKHFACLO_00754 1.48e-271 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
AKHFACLO_00755 3.17e-146 - - - S - - - Protein of unknown function (DUF4012)
AKHFACLO_00756 2.17e-170 - - - - - - - -
AKHFACLO_00757 2.12e-132 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_00758 2.88e-117 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_00759 7.1e-90 - - - M - - - Glycosyltransferase like family 2
AKHFACLO_00760 6.76e-68 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
AKHFACLO_00761 1.96e-187 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKHFACLO_00762 1.42e-236 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
AKHFACLO_00763 1.53e-169 - - - M - - - Protein of unknown function (DUF3152)
AKHFACLO_00764 3.99e-176 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
AKHFACLO_00766 5.85e-70 - - - E - - - Domain of unknown function (DUF5011)
AKHFACLO_00767 6.18e-33 - - - S - - - Parallel beta-helix repeats
AKHFACLO_00768 1.65e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
AKHFACLO_00769 1.51e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKHFACLO_00770 2.38e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
AKHFACLO_00771 6.47e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
AKHFACLO_00772 7.07e-244 - - - T - - - Pfam Adenylate and Guanylate cyclase catalytic domain
AKHFACLO_00774 1.94e-165 - - - - - - - -
AKHFACLO_00775 0.0 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKHFACLO_00776 5.34e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKHFACLO_00777 0.0 - 3.2.1.97 GH101 G ko:K17624 - ko00000,ko01000 Glycosyl hydrolase 101 beta sandwich domain
AKHFACLO_00778 5.21e-254 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
AKHFACLO_00779 1.24e-278 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
AKHFACLO_00780 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKHFACLO_00781 0.0 - - - S - - - Tetratricopeptide repeat
AKHFACLO_00782 1.68e-239 - - - S - - - Tetratricopeptide repeat
AKHFACLO_00783 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AKHFACLO_00784 3.63e-87 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
AKHFACLO_00785 3.64e-177 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_00786 3.37e-270 - - - E - - - Aminotransferase class I and II
AKHFACLO_00787 2.21e-178 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
AKHFACLO_00788 3.41e-136 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AKHFACLO_00789 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_00790 0.0 - - - EGP - - - Major Facilitator Superfamily
AKHFACLO_00792 9.65e-145 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
AKHFACLO_00795 0.0 - - - L - - - DEAD DEAH box helicase
AKHFACLO_00796 2.49e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
AKHFACLO_00797 2.68e-252 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00798 2.44e-143 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00799 2.4e-195 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
AKHFACLO_00800 5.87e-180 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
AKHFACLO_00801 1.59e-120 - - - S - - - Aminoacyl-tRNA editing domain
AKHFACLO_00802 1.78e-82 - - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_00803 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AKHFACLO_00804 7.38e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
AKHFACLO_00805 5.86e-299 - - - S - - - Domain of Unknown Function (DUF349)
AKHFACLO_00808 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
AKHFACLO_00809 2.42e-237 uspA - - T - - - Belongs to the universal stress protein A family
AKHFACLO_00810 1.49e-251 - - - S - - - Protein of unknown function (DUF3027)
AKHFACLO_00811 1.23e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
AKHFACLO_00812 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
AKHFACLO_00813 1.23e-171 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
AKHFACLO_00814 1.27e-227 - - - - - - - -
AKHFACLO_00815 8.25e-53 - - - S - - - Proteins of 100 residues with WXG
AKHFACLO_00816 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AKHFACLO_00817 1.49e-58 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
AKHFACLO_00818 7.36e-106 - - - S - - - LytR cell envelope-related transcriptional attenuator
AKHFACLO_00819 2.11e-185 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKHFACLO_00820 1.22e-251 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
AKHFACLO_00821 3.54e-223 - - - S - - - Protein of unknown function DUF58
AKHFACLO_00822 1.78e-121 - - - - - - - -
AKHFACLO_00823 1.12e-246 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
AKHFACLO_00824 2.85e-198 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
AKHFACLO_00825 9.23e-117 - - - - - - - -
AKHFACLO_00827 0.0 - - - S - - - PGAP1-like protein
AKHFACLO_00828 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
AKHFACLO_00829 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
AKHFACLO_00830 4.7e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
AKHFACLO_00831 1.36e-267 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
AKHFACLO_00832 3.5e-204 - - - S - - - Protein conserved in bacteria
AKHFACLO_00833 7.24e-106 - - - L - - - Phage integrase, N-terminal SAM-like domain
AKHFACLO_00834 1.9e-137 - - - L - - - Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKHFACLO_00835 2.5e-39 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
AKHFACLO_00837 1.15e-234 - - - S - - - Acetyltransferase (GNAT) domain
AKHFACLO_00839 3.96e-28 - - - S - - - Carbon-nitrogen hydrolase
AKHFACLO_00840 1.22e-129 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
AKHFACLO_00841 1.9e-74 - - - K - - - Transcriptional regulator
AKHFACLO_00842 2.67e-117 - - - K - - - FR47-like protein
AKHFACLO_00843 6.46e-162 - - - J - - - Acetyltransferase (GNAT) domain
AKHFACLO_00844 9.61e-84 - - - K - - - Protein of unknown function, DUF488
AKHFACLO_00845 1.71e-206 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AKHFACLO_00846 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_00847 2.02e-171 - - - S - - - Domain of unknown function (DUF4194)
AKHFACLO_00848 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_00849 0.0 - - - E - - - Serine carboxypeptidase
AKHFACLO_00850 4.05e-207 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
AKHFACLO_00851 2.45e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
AKHFACLO_00852 2.26e-215 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
AKHFACLO_00853 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
AKHFACLO_00854 1.93e-159 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
AKHFACLO_00855 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
AKHFACLO_00856 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
AKHFACLO_00857 6.31e-153 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
AKHFACLO_00858 4.89e-201 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
AKHFACLO_00859 4.95e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
AKHFACLO_00860 1.61e-250 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKHFACLO_00862 2.16e-165 - - - M - - - Peptidase family M23
AKHFACLO_00863 7.58e-73 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
AKHFACLO_00864 0.0 fadD1 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
AKHFACLO_00865 0.0 - - - G - - - ABC transporter substrate-binding protein
AKHFACLO_00866 1.35e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
AKHFACLO_00867 1.59e-255 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
AKHFACLO_00868 3.59e-118 - - - - - - - -
AKHFACLO_00869 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
AKHFACLO_00870 4.26e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AKHFACLO_00871 3.07e-188 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
AKHFACLO_00872 4.78e-188 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKHFACLO_00873 3.84e-165 - - - S - - - alpha beta
AKHFACLO_00874 6.31e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
AKHFACLO_00875 3.1e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AKHFACLO_00876 1.27e-226 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
AKHFACLO_00877 2.98e-289 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKHFACLO_00878 1.82e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AKHFACLO_00879 4.17e-97 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKHFACLO_00880 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKHFACLO_00881 3.02e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
AKHFACLO_00882 2.27e-222 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_00883 3.73e-213 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
AKHFACLO_00884 2.17e-93 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
AKHFACLO_00885 0.0 - - - S - - - Uncharacterized conserved protein (DUF2183)
AKHFACLO_00886 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
AKHFACLO_00887 3.62e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AKHFACLO_00888 2e-150 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
AKHFACLO_00889 2.7e-172 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
AKHFACLO_00890 0.0 pon1 - - M - - - Transglycosylase
AKHFACLO_00891 2.95e-167 - - - L - - - Transposase, Mutator family
AKHFACLO_00898 5.92e-313 - - - S ko:K06901 - ko00000,ko02000 Permease family
AKHFACLO_00900 1.29e-218 - - - S - - - Protein conserved in bacteria
AKHFACLO_00901 1.29e-189 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKHFACLO_00902 6.61e-234 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
AKHFACLO_00903 8.51e-219 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
AKHFACLO_00904 9.86e-262 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
AKHFACLO_00905 3.28e-166 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
AKHFACLO_00906 6.09e-310 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
AKHFACLO_00907 2.2e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AKHFACLO_00908 3.6e-305 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKHFACLO_00909 2.63e-142 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
AKHFACLO_00910 3.52e-309 - - - EGP - - - Major Facilitator Superfamily
AKHFACLO_00911 4.63e-276 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKHFACLO_00912 1.23e-232 - - - L - - - Excalibur calcium-binding domain
AKHFACLO_00913 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
AKHFACLO_00914 1.08e-123 - - - D - - - nuclear chromosome segregation
AKHFACLO_00915 1.51e-162 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AKHFACLO_00916 1.28e-185 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
AKHFACLO_00917 1.07e-238 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
AKHFACLO_00918 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
AKHFACLO_00919 9.61e-199 - - - L - - - Transposase and inactivated derivatives IS30 family
AKHFACLO_00920 6.85e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
AKHFACLO_00921 1.26e-55 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
AKHFACLO_00922 1.72e-128 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
AKHFACLO_00923 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKHFACLO_00924 2.57e-241 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKHFACLO_00925 7.52e-93 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
AKHFACLO_00926 0.0 - - - S - - - Predicted membrane protein (DUF2207)
AKHFACLO_00927 8.8e-120 lemA - - S ko:K03744 - ko00000 LemA family
AKHFACLO_00928 1.16e-145 xylR - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
AKHFACLO_00929 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AKHFACLO_00930 8.32e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKHFACLO_00931 1.28e-154 - - - - - - - -
AKHFACLO_00932 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
AKHFACLO_00933 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
AKHFACLO_00935 8.48e-207 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
AKHFACLO_00936 5.82e-130 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AKHFACLO_00938 1.35e-115 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
AKHFACLO_00939 7.48e-186 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
AKHFACLO_00940 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKHFACLO_00941 2.25e-156 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
AKHFACLO_00942 1.23e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
AKHFACLO_00943 6.41e-82 - - - T - - - Domain of unknown function (DUF4234)
AKHFACLO_00944 1.66e-131 - - - K - - - Bacterial regulatory proteins, tetR family
AKHFACLO_00945 7.03e-24 - - - - - - - -
AKHFACLO_00946 1.99e-62 tam 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
AKHFACLO_00947 9.61e-54 - - - K - - - Helix-turn-helix
AKHFACLO_00948 8.45e-286 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA N-terminal domain
AKHFACLO_00949 5.34e-90 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
AKHFACLO_00950 4.61e-226 - - - S ko:K07088 - ko00000 Membrane transport protein
AKHFACLO_00951 3.57e-120 - - - K - - - Transcriptional regulator PadR-like family
AKHFACLO_00952 1.02e-171 - - - L ko:K07457 - ko00000 endonuclease III
AKHFACLO_00953 2.8e-168 - - - S - - - Enoyl-(Acyl carrier protein) reductase
AKHFACLO_00954 3.27e-310 - - - V - - - MatE
AKHFACLO_00955 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AKHFACLO_00956 2.52e-07 - - - KLT - - - Protein tyrosine kinase
AKHFACLO_00957 8.59e-24 - - - K - - - Psort location Cytoplasmic, score
AKHFACLO_00958 2.23e-205 - - - - - - - -
AKHFACLO_00959 1.54e-248 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
AKHFACLO_00960 2.41e-23 - - - K - - - MerR family regulatory protein
AKHFACLO_00961 1.75e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AKHFACLO_00962 4.1e-229 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AKHFACLO_00963 1.77e-200 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
AKHFACLO_00964 1.33e-229 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
AKHFACLO_00965 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AKHFACLO_00966 1.83e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
AKHFACLO_00967 7.76e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
AKHFACLO_00968 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
AKHFACLO_00970 8.19e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
AKHFACLO_00971 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKHFACLO_00975 1.67e-169 - - - M - - - NLP P60 protein
AKHFACLO_00976 1.49e-87 - - - S - - - SPP1 phage holin
AKHFACLO_00978 2.44e-90 - - - - - - - -
AKHFACLO_00980 2.46e-292 - - - - - - - -
AKHFACLO_00981 4.08e-88 - - - - - - - -
AKHFACLO_00982 0.0 - - - S - - - Prophage endopeptidase tail
AKHFACLO_00983 2.5e-187 - - - S - - - phage tail
AKHFACLO_00984 0.0 - - - S - - - Phage-related minor tail protein
AKHFACLO_00985 1.77e-70 - - - - - - - -
AKHFACLO_00986 4.54e-108 - - - - - - - -
AKHFACLO_00987 8.94e-55 - - - - - - - -
AKHFACLO_00988 1.35e-49 - - - - - - - -
AKHFACLO_00989 1.65e-93 - - - - - - - -
AKHFACLO_00990 6.59e-96 - - - - - - - -
AKHFACLO_00991 3.65e-103 - - - - - - - -
AKHFACLO_00992 2.99e-119 - - - - - - - -
AKHFACLO_00993 3.74e-85 - - - - - - - -
AKHFACLO_00994 7.08e-225 - - - S - - - Phage capsid family
AKHFACLO_00995 2.47e-125 - - - - - - - -
AKHFACLO_00996 2.73e-58 - - - - - - - -
AKHFACLO_00997 7.81e-305 - - - - - - - -
AKHFACLO_00998 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
AKHFACLO_00999 0.0 - - - S - - - Terminase
AKHFACLO_01000 1.89e-91 - - - - - - - -
AKHFACLO_01001 1.32e-148 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
AKHFACLO_01002 6.57e-86 - - - - ko:K07451 - ko00000,ko01000,ko02048 -
AKHFACLO_01005 6.44e-74 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
AKHFACLO_01006 1.01e-230 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
AKHFACLO_01007 4.37e-149 - - - L ko:K07497 - ko00000 Integrase core domain
AKHFACLO_01008 6.6e-44 - - - L - - - Helix-turn-helix domain
AKHFACLO_01009 3.64e-33 - - - L - - - transposase activity
AKHFACLO_01011 9.08e-286 - - - K - - - Helix-turn-helix domain protein
AKHFACLO_01013 5.16e-167 - - - - - - - -
AKHFACLO_01014 1.35e-38 - - - - ko:K07485 - ko00000 -
AKHFACLO_01015 3.01e-82 - - - L ko:K07485 - ko00000 Transposase
AKHFACLO_01016 4.97e-121 - - - L ko:K07485 - ko00000 Transposase
AKHFACLO_01017 1.3e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AKHFACLO_01018 2.67e-149 - - - S ko:K07126 - ko00000 Sel1-like repeats.
AKHFACLO_01019 1.18e-207 - - - S ko:K11206 - ko00000,ko01000 Carbon-nitrogen hydrolase
AKHFACLO_01020 1.63e-231 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01021 1.67e-312 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
AKHFACLO_01022 5.23e-107 - - - - - - - -
AKHFACLO_01023 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
AKHFACLO_01024 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
AKHFACLO_01025 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
AKHFACLO_01026 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
AKHFACLO_01027 4.95e-18 - - - S ko:K07149 - ko00000 Membrane
AKHFACLO_01028 3.16e-310 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
AKHFACLO_01029 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AKHFACLO_01030 3.91e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
AKHFACLO_01031 1.61e-175 - - - S - - - UPF0126 domain
AKHFACLO_01032 1.87e-128 - - - T - - - RNA ligase
AKHFACLO_01033 1.58e-287 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
AKHFACLO_01034 1.66e-128 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AKHFACLO_01035 4.21e-242 - - - S ko:K06889 - ko00000 alpha beta
AKHFACLO_01036 1.72e-306 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AKHFACLO_01037 1.08e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
AKHFACLO_01038 6.9e-259 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
AKHFACLO_01040 2.78e-308 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKHFACLO_01041 9.32e-164 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AKHFACLO_01042 4.05e-147 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AKHFACLO_01043 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
AKHFACLO_01044 3.81e-309 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AKHFACLO_01045 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
AKHFACLO_01046 1.94e-146 - - - S - - - Protein of unknown function (DUF3000)
AKHFACLO_01047 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKHFACLO_01048 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
AKHFACLO_01049 2.24e-51 - - - - - - - -
AKHFACLO_01050 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKHFACLO_01051 1.15e-284 - - - S - - - Peptidase dimerisation domain
AKHFACLO_01052 5.48e-114 - - - P - - - ABC-type metal ion transport system permease component
AKHFACLO_01053 6.76e-213 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
AKHFACLO_01054 1.57e-223 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKHFACLO_01055 4.36e-46 - - - - - - - -
AKHFACLO_01056 2.85e-65 - - - - - - - -
AKHFACLO_01058 5.46e-152 - - - - - - - -
AKHFACLO_01059 3.31e-39 - - - - - - - -
AKHFACLO_01060 3.44e-262 - - - S - - - Helix-turn-helix domain
AKHFACLO_01061 1.42e-56 - - - - - - - -
AKHFACLO_01062 2.93e-118 - - - S - - - Transcription factor WhiB
AKHFACLO_01063 2.09e-150 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
AKHFACLO_01064 1.96e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKHFACLO_01065 0.0 corC - - S - - - CBS domain
AKHFACLO_01066 1.82e-130 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AKHFACLO_01067 2.03e-251 phoH - - T ko:K06217 - ko00000 PhoH-like protein
AKHFACLO_01068 1.37e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
AKHFACLO_01069 8.86e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AKHFACLO_01071 1.78e-208 spoU2 - - J - - - SpoU rRNA Methylase family
AKHFACLO_01072 1.42e-308 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AKHFACLO_01073 2.56e-141 - - - S - - - Iron-sulfur cluster assembly protein
AKHFACLO_01074 4.14e-132 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
AKHFACLO_01075 1.21e-304 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKHFACLO_01076 2.13e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
AKHFACLO_01077 2.92e-298 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
AKHFACLO_01078 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
AKHFACLO_01079 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AKHFACLO_01081 9.66e-307 pbuX - - F ko:K03458 - ko00000 Permease family
AKHFACLO_01082 1.54e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AKHFACLO_01083 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_01084 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
AKHFACLO_01085 2.46e-84 - - - S - - - Domain of unknown function (DUF4418)
AKHFACLO_01086 1.87e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
AKHFACLO_01087 6.67e-173 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
AKHFACLO_01088 1.83e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKHFACLO_01089 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_01090 7.56e-174 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
AKHFACLO_01091 4.03e-85 - - - S - - - Bacterial protein of unknown function (DUF948)
AKHFACLO_01092 7.33e-50 - - - - - - - -
AKHFACLO_01093 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKHFACLO_01094 2.86e-90 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKHFACLO_01095 1.82e-246 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AKHFACLO_01096 5.3e-69 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
AKHFACLO_01097 1.57e-280 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AKHFACLO_01098 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKHFACLO_01099 2.27e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
AKHFACLO_01100 3.44e-135 - - - - - - - -
AKHFACLO_01101 3.6e-154 - - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_01102 1.31e-05 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
AKHFACLO_01103 9.05e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
AKHFACLO_01104 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
AKHFACLO_01105 4.2e-52 - - - S - - - Protein of unknown function (DUF2975)
AKHFACLO_01106 5.76e-35 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
AKHFACLO_01107 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
AKHFACLO_01108 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
AKHFACLO_01109 3.3e-300 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
AKHFACLO_01110 5.89e-235 - - - S - - - Protein of unknown function (DUF3071)
AKHFACLO_01111 2.45e-63 - - - S - - - Domain of unknown function (DUF4193)
AKHFACLO_01112 1.23e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AKHFACLO_01113 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKHFACLO_01114 1.35e-38 - - - - - - - -
AKHFACLO_01116 1.31e-265 - - - E - - - Belongs to the peptidase S1B family
AKHFACLO_01117 3.85e-145 - - - L - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_01118 2.38e-41 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AKHFACLO_01119 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
AKHFACLO_01120 2.48e-231 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKHFACLO_01121 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AKHFACLO_01122 8.76e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKHFACLO_01123 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKHFACLO_01124 4.49e-297 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
AKHFACLO_01125 3.15e-276 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKHFACLO_01126 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
AKHFACLO_01127 2.64e-228 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
AKHFACLO_01128 2.52e-55 int8 - - L - - - Phage integrase family
AKHFACLO_01129 2.15e-31 - - - - - - - -
AKHFACLO_01133 1.18e-45 - - - S - - - Predicted membrane protein (DUF2335)
AKHFACLO_01134 2.16e-35 - - - K - - - Transcriptional regulator
AKHFACLO_01137 4.04e-16 - - - L - - - Phage integrase family
AKHFACLO_01138 2.92e-27 int8 - - L - - - Phage integrase family
AKHFACLO_01139 2.79e-53 int8 - - L - - - Phage integrase family
AKHFACLO_01142 2.9e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AKHFACLO_01143 3.73e-301 - - - G - - - Major Facilitator Superfamily
AKHFACLO_01144 2.87e-217 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
AKHFACLO_01145 5.33e-286 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
AKHFACLO_01146 3.42e-169 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
AKHFACLO_01147 2.9e-276 - - - GK - - - ROK family
AKHFACLO_01148 5.93e-196 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AKHFACLO_01149 4.41e-309 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
AKHFACLO_01150 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
AKHFACLO_01151 2.16e-242 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_01152 5.32e-249 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_01153 0.0 - - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AKHFACLO_01154 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
AKHFACLO_01155 7.52e-126 - - - F - - - NUDIX domain
AKHFACLO_01157 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
AKHFACLO_01158 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
AKHFACLO_01159 1.46e-165 - 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
AKHFACLO_01160 1.79e-309 - 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp
AKHFACLO_01161 2.77e-292 - 2.6.1.33 - M ko:K20429 - ko00000,ko01000 DegT/DnrJ/EryC1/StrS aminotransferase family
AKHFACLO_01162 5.99e-243 - - - V - - - Acetyltransferase (GNAT) domain
AKHFACLO_01163 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKHFACLO_01164 5.75e-148 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AKHFACLO_01165 2.76e-83 - - - - - - - -
AKHFACLO_01166 6.49e-249 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
AKHFACLO_01167 3.63e-228 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AKHFACLO_01168 1.49e-119 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKHFACLO_01169 3.39e-254 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AKHFACLO_01170 4.07e-167 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
AKHFACLO_01172 5.1e-146 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKHFACLO_01173 3.31e-35 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
AKHFACLO_01174 5.46e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKHFACLO_01175 9.73e-228 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
AKHFACLO_01176 5.82e-131 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
AKHFACLO_01177 3.39e-193 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKHFACLO_01178 4.75e-126 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKHFACLO_01179 2.99e-191 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
AKHFACLO_01180 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AKHFACLO_01181 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
AKHFACLO_01182 4.74e-211 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
AKHFACLO_01183 1.77e-298 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
AKHFACLO_01184 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
AKHFACLO_01185 2.14e-108 - - - - - - - -
AKHFACLO_01186 8.32e-253 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
AKHFACLO_01187 1.8e-246 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
AKHFACLO_01188 2.67e-56 - - - - - - - -
AKHFACLO_01189 1.93e-235 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
AKHFACLO_01190 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_01192 0.0 - - - D - - - Cell surface antigen C-terminus
AKHFACLO_01193 5.33e-36 - - - - - - - -
AKHFACLO_01194 9.88e-180 - - - - - - - -
AKHFACLO_01195 6.15e-84 - - - S - - - PrgI family protein
AKHFACLO_01196 0.0 - - - U - - - type IV secretory pathway VirB4
AKHFACLO_01197 1.7e-265 - - - M - - - CHAP domain
AKHFACLO_01199 7.45e-228 - - - - ko:K03646 - ko00000,ko02000 -
AKHFACLO_01201 5.17e-124 - - - K - - - Helix-turn-helix domain protein
AKHFACLO_01204 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
AKHFACLO_01205 7.59e-41 - - - - - - - -
AKHFACLO_01206 3.43e-52 - - - - - - - -
AKHFACLO_01207 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AKHFACLO_01209 0.0 - - - - - - - -
AKHFACLO_01210 2.38e-217 - - - S - - - Protein of unknown function (DUF3801)
AKHFACLO_01211 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
AKHFACLO_01212 1.33e-67 - - - S - - - Bacterial mobilisation protein (MobC)
AKHFACLO_01213 6.75e-54 - - - S - - - Protein of unknown function (DUF2442)
AKHFACLO_01214 5.27e-69 - - - - - - - -
AKHFACLO_01215 9.09e-86 - - - - - - - -
AKHFACLO_01216 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
AKHFACLO_01217 1.35e-108 - - - - - - - -
AKHFACLO_01218 3.35e-87 - - - - - - - -
AKHFACLO_01219 7.9e-74 - - - - - - - -
AKHFACLO_01220 5.86e-294 - - - S - - - HipA-like C-terminal domain
AKHFACLO_01221 2.59e-70 - - - H - - - Flavin containing amine oxidoreductase
AKHFACLO_01222 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AKHFACLO_01223 1.18e-296 - 2.6.1.1 - E ko:K00812,ko:K10907 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
AKHFACLO_01224 8.96e-117 lrp_3 - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
AKHFACLO_01225 9.37e-96 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
AKHFACLO_01226 0.0 - - - S - - - domain protein
AKHFACLO_01227 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
AKHFACLO_01228 6.07e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKHFACLO_01229 6.95e-212 iaaA 3.4.19.5 - E ko:K13051 - ko00000,ko01000,ko01002 Asparaginase
AKHFACLO_01230 1.1e-188 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
AKHFACLO_01231 2.12e-236 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
AKHFACLO_01232 9.06e-235 acoB 1.2.4.1, 1.2.4.4 - C ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
AKHFACLO_01233 8.13e-263 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AKHFACLO_01234 1.97e-122 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_01235 1.55e-293 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
AKHFACLO_01236 7.17e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AKHFACLO_01237 8.04e-313 - - - K - - - Fic/DOC family
AKHFACLO_01238 7.83e-162 - - - E - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_01239 5.59e-78 yccF - - S - - - Inner membrane component domain
AKHFACLO_01240 1.49e-199 - - - J - - - Methyltransferase domain
AKHFACLO_01241 4.93e-107 - - - S - - - Cupin 2, conserved barrel domain protein
AKHFACLO_01242 0.0 - - - KLT - - - Protein tyrosine kinase
AKHFACLO_01243 6.04e-103 - - - K - - - Psort location Cytoplasmic, score
AKHFACLO_01245 1.1e-30 - - - - - - - -
AKHFACLO_01246 1.83e-278 - - - S - - - Short C-terminal domain
AKHFACLO_01247 5.22e-111 - - - S - - - Helix-turn-helix
AKHFACLO_01248 4.07e-85 - - - S - - - Zincin-like metallopeptidase
AKHFACLO_01249 1.66e-46 - - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AKHFACLO_01250 2.1e-49 - - - - - - - -
AKHFACLO_01251 1.5e-96 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
AKHFACLO_01252 7.47e-161 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
AKHFACLO_01253 0.0 - 2.7.11.1 - S ko:K12132 - ko00000,ko01000,ko01001 PASTA domain
AKHFACLO_01255 0.0 - - - M - - - Glycosyltransferase like family 2
AKHFACLO_01256 1.3e-152 - - - E - - - haloacid dehalogenase-like hydrolase
AKHFACLO_01257 1.49e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
AKHFACLO_01258 3.71e-239 - - - S - - - Conserved hypothetical protein 698
AKHFACLO_01259 4.12e-79 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
AKHFACLO_01260 1.72e-204 - - - G - - - Phosphoglycerate mutase family
AKHFACLO_01261 6.47e-303 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
AKHFACLO_01262 6.67e-56 - - - K - - - AraC-like ligand binding domain
AKHFACLO_01264 3.47e-69 - - - IQ - - - oxidoreductase activity
AKHFACLO_01265 2.65e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
AKHFACLO_01266 1.61e-163 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01267 1.11e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKHFACLO_01268 1.51e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKHFACLO_01269 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
AKHFACLO_01270 1.04e-138 - - - - - - - -
AKHFACLO_01271 4.51e-261 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKHFACLO_01272 3.67e-275 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AKHFACLO_01273 4.12e-227 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
AKHFACLO_01274 4.83e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
AKHFACLO_01275 2.51e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKHFACLO_01276 1.29e-112 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
AKHFACLO_01277 5.96e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
AKHFACLO_01278 2.67e-15 - - - L - - - Transposase and inactivated derivatives IS30 family
AKHFACLO_01279 2.2e-86 - - - L - - - Transposase and inactivated derivatives IS30 family
AKHFACLO_01280 1.78e-65 - - - M - - - Parallel beta-helix repeats
AKHFACLO_01282 1.67e-113 - - - K - - - MarR family
AKHFACLO_01283 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_01284 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
AKHFACLO_01285 1.86e-219 - - - S - - - Patatin-like phospholipase
AKHFACLO_01286 2.72e-196 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
AKHFACLO_01287 1.48e-215 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
AKHFACLO_01288 1.68e-147 - - - S - - - Vitamin K epoxide reductase
AKHFACLO_01289 1.04e-212 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
AKHFACLO_01290 3.66e-41 - - - S - - - Protein of unknown function (DUF3107)
AKHFACLO_01291 3.9e-266 mphA - - S - - - Aminoglycoside phosphotransferase
AKHFACLO_01292 7.28e-59 mphA - - S - - - Aminoglycoside phosphotransferase
AKHFACLO_01293 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
AKHFACLO_01294 0.0 - - - S - - - Zincin-like metallopeptidase
AKHFACLO_01295 4.13e-193 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
AKHFACLO_01296 2.24e-86 - - - S - - - Protein of unknown function (DUF3052)
AKHFACLO_01297 4.8e-249 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AKHFACLO_01298 1.52e-81 - - - S - - - Thiamine-binding protein
AKHFACLO_01299 5.12e-211 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
AKHFACLO_01300 3.43e-291 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
AKHFACLO_01301 1.62e-110 - - - - - - - -
AKHFACLO_01302 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AKHFACLO_01303 8.53e-188 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AKHFACLO_01304 1.5e-203 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AKHFACLO_01305 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
AKHFACLO_01306 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
AKHFACLO_01307 4.69e-314 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKHFACLO_01308 8.03e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKHFACLO_01309 9.4e-105 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AKHFACLO_01310 1.35e-56 - - - S ko:K02221 - ko00000,ko02044 YGGT family
AKHFACLO_01311 1.65e-191 - - - V - - - DivIVA protein
AKHFACLO_01312 4.6e-148 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AKHFACLO_01313 1.62e-226 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
AKHFACLO_01314 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
AKHFACLO_01315 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
AKHFACLO_01316 2.77e-290 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
AKHFACLO_01317 3.02e-229 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01318 1.06e-57 pacL 3.6.3.8, 3.6.3.9 - P ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 ko00000,ko00001,ko01000,ko04147 ATPase, P-type transporting, HAD superfamily, subfamily IC
AKHFACLO_01319 5.92e-298 - - - T - - - Histidine kinase
AKHFACLO_01320 2.19e-153 - - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_01321 4.91e-150 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
AKHFACLO_01322 7.55e-243 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
AKHFACLO_01323 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
AKHFACLO_01324 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
AKHFACLO_01325 1.57e-21 - - - L - - - This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AKHFACLO_01326 1.34e-130 - - - T - - - protein histidine kinase activity
AKHFACLO_01327 5.42e-67 - - - S - - - Protein of unknown function (DUF3073)
AKHFACLO_01328 1.2e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
AKHFACLO_01329 2.37e-248 - - - S - - - Protein conserved in bacteria
AKHFACLO_01330 4.92e-224 - - - S - - - Amidohydrolase family
AKHFACLO_01331 0.0 - - - S - - - Threonine/Serine exporter, ThrE
AKHFACLO_01332 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AKHFACLO_01333 9.66e-309 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
AKHFACLO_01334 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
AKHFACLO_01335 1.01e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
AKHFACLO_01336 6.08e-154 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
AKHFACLO_01337 1.43e-98 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AKHFACLO_01338 3.36e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
AKHFACLO_01339 8.1e-240 - - - EG - - - EamA-like transporter family
AKHFACLO_01340 2.68e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
AKHFACLO_01341 3.45e-174 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
AKHFACLO_01342 0.0 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
AKHFACLO_01343 1.49e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
AKHFACLO_01344 6.23e-102 ulaC 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AKHFACLO_01345 3.09e-245 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AKHFACLO_01346 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
AKHFACLO_01349 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 arabinose metabolic process
AKHFACLO_01350 9.15e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AKHFACLO_01351 4.44e-160 gntR - - K - - - FCD
AKHFACLO_01352 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
AKHFACLO_01354 3.62e-218 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
AKHFACLO_01355 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
AKHFACLO_01358 1.23e-116 - - - K - - - Putative zinc ribbon domain
AKHFACLO_01359 4.36e-162 - - - S - - - GyrI-like small molecule binding domain
AKHFACLO_01360 5.19e-32 - - - L - - - DNA integration
AKHFACLO_01362 2.84e-82 - - - - - - - -
AKHFACLO_01363 6.86e-154 merR2 - - K - - - helix_turn_helix, mercury resistance
AKHFACLO_01364 2.88e-96 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
AKHFACLO_01365 2.65e-180 - - - S - - - Bacterial protein of unknown function (DUF881)
AKHFACLO_01366 2.78e-57 sbp - - S - - - Protein of unknown function (DUF1290)
AKHFACLO_01367 5.59e-223 - - - S - - - Bacterial protein of unknown function (DUF881)
AKHFACLO_01368 1.5e-149 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKHFACLO_01369 1.07e-200 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
AKHFACLO_01370 1.2e-54 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
AKHFACLO_01371 8.92e-144 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
AKHFACLO_01372 2.07e-237 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKHFACLO_01373 1.07e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AKHFACLO_01374 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AKHFACLO_01375 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
AKHFACLO_01376 9.44e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
AKHFACLO_01377 1.15e-165 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
AKHFACLO_01378 5.17e-56 - - - - - - - -
AKHFACLO_01379 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
AKHFACLO_01380 1.65e-315 - - - - - - - -
AKHFACLO_01381 1.58e-210 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AKHFACLO_01382 4.72e-284 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
AKHFACLO_01383 3.9e-131 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AKHFACLO_01384 3.73e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
AKHFACLO_01385 2.31e-257 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AKHFACLO_01386 1.83e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AKHFACLO_01388 2.64e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AKHFACLO_01389 2.79e-176 yebC - - K - - - transcriptional regulatory protein
AKHFACLO_01390 0.0 - 3.2.1.52 GH20 M ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
AKHFACLO_01391 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKHFACLO_01392 0.0 - - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AKHFACLO_01395 0.0 - - - - - - - -
AKHFACLO_01399 2.89e-199 - - - S - - - PAC2 family
AKHFACLO_01400 8.18e-216 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AKHFACLO_01401 8.17e-204 - - - G - - - Fructosamine kinase
AKHFACLO_01402 6.31e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AKHFACLO_01403 1.2e-281 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AKHFACLO_01404 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
AKHFACLO_01405 4.49e-258 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AKHFACLO_01406 3.12e-182 - - - S - - - Protein of unknown function (DUF1275)
AKHFACLO_01407 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
AKHFACLO_01410 4.27e-308 - - - V - - - MatE
AKHFACLO_01411 3.47e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
AKHFACLO_01412 4.12e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
AKHFACLO_01413 1.2e-45 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
AKHFACLO_01414 3.84e-189 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKHFACLO_01415 3.88e-283 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
AKHFACLO_01416 3.23e-222 whiA - - K ko:K09762 - ko00000 May be required for sporulation
AKHFACLO_01417 1.23e-226 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
AKHFACLO_01418 2.49e-229 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
AKHFACLO_01419 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AKHFACLO_01420 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AKHFACLO_01421 3.39e-112 - - - - - - - -
AKHFACLO_01422 8.93e-77 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
AKHFACLO_01423 2.13e-151 - - - K - - - Transcriptional regulatory protein, C terminal
AKHFACLO_01424 3.04e-315 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
AKHFACLO_01425 2.4e-180 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
AKHFACLO_01426 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
AKHFACLO_01427 6.83e-253 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
AKHFACLO_01428 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
AKHFACLO_01429 4.9e-264 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
AKHFACLO_01430 7.42e-277 - - - GK - - - ROK family
AKHFACLO_01431 1.69e-228 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
AKHFACLO_01432 5.99e-64 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
AKHFACLO_01433 1.69e-169 - - - K - - - Bacterial regulatory proteins, tetR family
AKHFACLO_01434 7.05e-291 - - - G - - - Transmembrane secretion effector
AKHFACLO_01435 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKHFACLO_01436 6.14e-280 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
AKHFACLO_01437 7.14e-238 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
AKHFACLO_01439 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_01440 3.31e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKHFACLO_01441 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKHFACLO_01442 1.59e-179 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
AKHFACLO_01443 2.91e-315 - - - S - - - Calcineurin-like phosphoesterase
AKHFACLO_01446 5.38e-85 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
AKHFACLO_01447 1.97e-122 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
AKHFACLO_01448 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKHFACLO_01450 4.53e-157 - - - S - - - HAD hydrolase, family IA, variant 3
AKHFACLO_01451 4.84e-256 - - - P - - - NMT1/THI5 like
AKHFACLO_01452 5.83e-178 - - - P - - - Binding-protein-dependent transport system inner membrane component
AKHFACLO_01453 2.16e-197 - - - - - - - -
AKHFACLO_01454 4.52e-161 - - - G - - - Phosphoglycerate mutase family
AKHFACLO_01455 0.0 - - - EGP - - - Major Facilitator Superfamily
AKHFACLO_01456 1.45e-125 - - - S - - - GtrA-like protein
AKHFACLO_01457 9.48e-83 - - - S - - - Macrophage migration inhibitory factor (MIF)
AKHFACLO_01458 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
AKHFACLO_01459 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
AKHFACLO_01460 3.03e-139 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
AKHFACLO_01461 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
AKHFACLO_01463 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
AKHFACLO_01464 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_01465 8.73e-122 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
AKHFACLO_01466 5.18e-243 - - - C - - - Aldo/keto reductase family
AKHFACLO_01467 1.19e-130 - - - M - - - Belongs to the glycosyl hydrolase 30 family
AKHFACLO_01468 4.45e-21 - - - - - - - -
AKHFACLO_01470 7.87e-70 - - - - - - - -
AKHFACLO_01471 9.07e-119 - - - T - - - AAA domain
AKHFACLO_01472 1.35e-268 - - - T - - - AAA domain
AKHFACLO_01473 0.0 - - - S - - - FRG domain
AKHFACLO_01474 2.72e-239 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AKHFACLO_01475 3.3e-24 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AKHFACLO_01476 2.78e-223 - - - S - - - Domain of unknown function (DUF4928)
AKHFACLO_01477 7.26e-34 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
AKHFACLO_01479 5.01e-55 - - - S - - - Bacterial mobilisation protein (MobC)
AKHFACLO_01480 3.76e-163 - - - S - - - Domain of unknown function (DUF4417)
AKHFACLO_01482 4.37e-80 - - - - - - - -
AKHFACLO_01483 4.81e-84 - - - - - - - -
AKHFACLO_01484 7.82e-65 - - - E - - - IrrE N-terminal-like domain
AKHFACLO_01486 1.42e-74 - - - K - - - Cro/C1-type HTH DNA-binding domain
AKHFACLO_01487 0.0 - 3.2.1.8, 3.5.1.104 - G ko:K01181,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
AKHFACLO_01488 2.17e-253 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
AKHFACLO_01489 1.94e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKHFACLO_01490 1.9e-188 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKHFACLO_01491 2.38e-249 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AKHFACLO_01492 5.41e-100 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
AKHFACLO_01493 0.0 scrT - - G - - - Transporter major facilitator family protein
AKHFACLO_01494 0.0 - - - EGP - - - Sugar (and other) transporter
AKHFACLO_01495 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
AKHFACLO_01497 4.31e-277 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
AKHFACLO_01498 0.0 - - - S - - - Domain of unknown function (DUF4037)
AKHFACLO_01499 5.31e-143 - - - S - - - Protein of unknown function (DUF4125)
AKHFACLO_01500 1.3e-195 - - - - - - - -
AKHFACLO_01501 0.0 pspC - - KT - - - PspC domain
AKHFACLO_01502 0.0 tcsS3 - - KT - - - PspC domain
AKHFACLO_01503 1.18e-162 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_01504 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AKHFACLO_01506 5.83e-181 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
AKHFACLO_01507 2.16e-239 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
AKHFACLO_01508 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKHFACLO_01509 1.77e-120 - - - - - - - -
AKHFACLO_01511 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
AKHFACLO_01513 2.32e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AKHFACLO_01514 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
AKHFACLO_01515 2.27e-270 - - - I - - - Diacylglycerol kinase catalytic domain
AKHFACLO_01516 2.41e-196 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
AKHFACLO_01517 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
AKHFACLO_01519 5.93e-60 - - - M - - - Spy0128-like isopeptide containing domain
AKHFACLO_01521 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
AKHFACLO_01522 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKHFACLO_01523 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
AKHFACLO_01524 2.41e-258 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKHFACLO_01525 1.28e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKHFACLO_01526 5.18e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
AKHFACLO_01527 2.81e-141 - - - - - - - -
AKHFACLO_01528 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
AKHFACLO_01529 7.87e-213 - - - - - - - -
AKHFACLO_01530 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
AKHFACLO_01531 1.9e-05 - - - M - - - Parallel beta-helix repeats
AKHFACLO_01535 2.18e-183 - - - - - - - -
AKHFACLO_01536 1.43e-95 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKHFACLO_01537 1.23e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AKHFACLO_01538 4.22e-221 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
AKHFACLO_01539 6.94e-241 - - - - - - - -
AKHFACLO_01540 6.86e-231 - - - - - - - -
AKHFACLO_01541 2.52e-214 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
AKHFACLO_01542 4.54e-151 - - - S - - - CYTH
AKHFACLO_01544 4.87e-236 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
AKHFACLO_01545 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AKHFACLO_01547 5.72e-199 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
AKHFACLO_01548 2.67e-145 - - - S - - - Domain of unknown function (DUF4854)
AKHFACLO_01549 1.31e-270 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
AKHFACLO_01550 0.0 - - - M - - - LPXTG cell wall anchor motif
AKHFACLO_01551 0.0 - - - M - - - domain protein
AKHFACLO_01552 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
AKHFACLO_01553 8.71e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
AKHFACLO_01554 7.87e-195 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
AKHFACLO_01555 0.0 - - - - - - - -
AKHFACLO_01556 8.27e-187 - - - QT - - - PucR C-terminal helix-turn-helix domain
AKHFACLO_01557 1.83e-167 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AKHFACLO_01558 1.39e-66 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
AKHFACLO_01559 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKHFACLO_01560 7.83e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKHFACLO_01561 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKHFACLO_01562 5.66e-192 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKHFACLO_01563 1.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKHFACLO_01564 2.39e-41 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKHFACLO_01565 3.54e-188 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
AKHFACLO_01566 2.41e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKHFACLO_01568 2.17e-47 - - - - - - - -
AKHFACLO_01569 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
AKHFACLO_01570 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
AKHFACLO_01571 1.13e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AKHFACLO_01573 2.52e-60 - - - L - - - PFAM Integrase catalytic
AKHFACLO_01574 2.45e-28 - - - L - - - PFAM Integrase catalytic
AKHFACLO_01575 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
AKHFACLO_01576 8.48e-215 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_01577 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
AKHFACLO_01578 5.71e-201 - - - S - - - Putative ABC-transporter type IV
AKHFACLO_01579 3.62e-212 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
AKHFACLO_01580 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
AKHFACLO_01581 1.92e-75 - - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
AKHFACLO_01582 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
AKHFACLO_01583 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
AKHFACLO_01584 1.29e-92 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
AKHFACLO_01585 2.93e-234 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
AKHFACLO_01586 1.75e-151 safC - - S - - - O-methyltransferase
AKHFACLO_01587 4.26e-222 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
AKHFACLO_01588 9.66e-290 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AKHFACLO_01589 7.4e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
AKHFACLO_01591 1.67e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKHFACLO_01592 8.53e-95 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
AKHFACLO_01593 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
AKHFACLO_01594 4.4e-126 - - - - - - - -
AKHFACLO_01596 2.41e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
AKHFACLO_01597 8.88e-138 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
AKHFACLO_01598 3.44e-130 - - - D - - - Septum formation initiator
AKHFACLO_01599 7.41e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AKHFACLO_01600 2.04e-194 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 - E ko:K00826,ko:K01665,ko:K02619,ko:K03342 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 branched-chain-amino-acid transaminase activity
AKHFACLO_01601 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01657,ko:K01665,ko:K03342,ko:K13950 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000,ko01007 chorismate binding enzyme
AKHFACLO_01602 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKHFACLO_01603 3.48e-146 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AKHFACLO_01604 9.1e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
AKHFACLO_01605 9.54e-43 rfbB2 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
AKHFACLO_01606 9.3e-260 - 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AKHFACLO_01607 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
AKHFACLO_01608 2.68e-292 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
AKHFACLO_01609 1.14e-252 - - - - - - - -
AKHFACLO_01610 1.7e-194 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01611 4.36e-244 - - - V - - - N-Acetylmuramoyl-L-alanine amidase
AKHFACLO_01613 0.0 argE - - E - - - Peptidase dimerisation domain
AKHFACLO_01614 2.07e-134 - - - S - - - Protein of unknown function (DUF3043)
AKHFACLO_01615 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKHFACLO_01616 4.99e-181 - - - S - - - Domain of unknown function (DUF4191)
AKHFACLO_01617 3.14e-181 nfrA - - C - - - Nitroreductase family
AKHFACLO_01618 9.49e-90 - - - S - - - Protein of unknown function (DUF4235)
AKHFACLO_01619 1.02e-171 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
AKHFACLO_01621 3.34e-244 - - - K - - - Psort location Cytoplasmic, score
AKHFACLO_01622 0.0 strK 3.1.3.1, 3.1.3.39 - P ko:K01077,ko:K04342 ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
AKHFACLO_01623 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
AKHFACLO_01624 3.29e-80 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKHFACLO_01625 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
AKHFACLO_01626 0.0 - - - K - - - WYL domain
AKHFACLO_01627 6.15e-69 - - - - - - - -
AKHFACLO_01628 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
AKHFACLO_01629 1.11e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
AKHFACLO_01630 5.93e-183 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
AKHFACLO_01632 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
AKHFACLO_01633 1.27e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AKHFACLO_01634 4.1e-39 - - - J - - - Acetyltransferase (GNAT) domain
AKHFACLO_01635 2.63e-121 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKHFACLO_01636 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
AKHFACLO_01637 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKHFACLO_01638 3.55e-313 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
AKHFACLO_01639 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AKHFACLO_01640 3.19e-205 - - - K - - - Helix-turn-helix domain, rpiR family
AKHFACLO_01641 1.88e-292 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
AKHFACLO_01642 2.12e-59 - - - S ko:K06990 - ko00000,ko04812 Memo-like protein
AKHFACLO_01643 0.0 - - - - - - - -
AKHFACLO_01644 7.01e-128 - - - K - - - cell envelope-related transcriptional attenuator
AKHFACLO_01646 5.21e-48 - - - L - - - Transposase
AKHFACLO_01647 2.34e-311 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_01648 2.67e-142 - - - S - - - Protein of unknown function (DUF1294)
AKHFACLO_01649 1.19e-210 - - - P ko:K07133 - ko00000 Domain of unknown function (DUF4143)
AKHFACLO_01653 3.05e-57 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKHFACLO_01654 1.62e-21 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKHFACLO_01656 5.11e-146 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
AKHFACLO_01657 2.14e-87 - - - G ko:K02027 - ko00000,ko00002,ko02000 carbohydrate transport
AKHFACLO_01658 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
AKHFACLO_01659 2e-158 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
AKHFACLO_01660 2.17e-243 - - - K - - - Periplasmic binding protein domain
AKHFACLO_01661 7.12e-25 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
AKHFACLO_01662 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
AKHFACLO_01663 7.3e-24 - - - L - - - Helix-turn-helix domain
AKHFACLO_01664 1.47e-11 - - - S - - - Protein of unknown function (DUF2442)
AKHFACLO_01665 8.59e-23 - - - K - - - Helix-turn-helix domain
AKHFACLO_01666 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
AKHFACLO_01667 1.66e-286 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
AKHFACLO_01668 4.11e-135 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01669 0.0 - - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
AKHFACLO_01670 4.03e-71 - - - K - - - MerR, DNA binding
AKHFACLO_01671 2.46e-248 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
AKHFACLO_01672 2.92e-131 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
AKHFACLO_01673 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
AKHFACLO_01674 6.17e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
AKHFACLO_01675 1.53e-193 - - - S - - - Short repeat of unknown function (DUF308)
AKHFACLO_01676 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
AKHFACLO_01677 6.9e-157 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
AKHFACLO_01678 3.13e-218 - - - - - - - -
AKHFACLO_01679 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AKHFACLO_01681 0.0 - - - L - - - PIF1-like helicase
AKHFACLO_01682 5.74e-205 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
AKHFACLO_01683 6.15e-153 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
AKHFACLO_01684 2.96e-55 - - - KT ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
AKHFACLO_01685 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
AKHFACLO_01686 2.05e-233 - - - L - - - Tetratricopeptide repeat
AKHFACLO_01687 1.13e-218 - - - M - - - Glycosyl transferase family 2
AKHFACLO_01688 0.0 - - - M - - - Glycosyl hydrolases family 25
AKHFACLO_01689 3.88e-37 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
AKHFACLO_01690 1.02e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKHFACLO_01691 1.4e-170 - - - S - - - SOS response associated peptidase (SRAP)
AKHFACLO_01692 6.09e-161 - - - - - - - -
AKHFACLO_01693 6.51e-104 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AKHFACLO_01694 6.84e-227 - - - M - - - heme binding
AKHFACLO_01695 2.24e-38 - - - EGP ko:K03446,ko:K03466,ko:K03762,ko:K08217 - br01600,ko00000,ko00002,ko01504,ko02000,ko03036 Major facilitator Superfamily
AKHFACLO_01696 2.11e-124 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
AKHFACLO_01698 1.52e-204 - - - - - - - -
AKHFACLO_01699 1.61e-125 - - - S - - - Putative ABC-transporter type IV
AKHFACLO_01700 5.99e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
AKHFACLO_01701 7.92e-247 - - - V - - - VanZ like family
AKHFACLO_01702 1.82e-187 - - - KT - - - RESPONSE REGULATOR receiver
AKHFACLO_01706 5.12e-280 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
AKHFACLO_01707 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AKHFACLO_01708 8.2e-56 - - - L - - - Transposase DDE domain
AKHFACLO_01709 1.97e-38 - - - L ko:K07483 - ko00000 Transposase
AKHFACLO_01710 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
AKHFACLO_01711 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
AKHFACLO_01713 3.26e-175 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
AKHFACLO_01714 5.1e-140 - - - - - - - -
AKHFACLO_01715 5.24e-150 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
AKHFACLO_01716 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
AKHFACLO_01717 3.15e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKHFACLO_01718 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
AKHFACLO_01719 6.98e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
AKHFACLO_01720 6.33e-227 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01721 6.5e-163 - - - S - - - ABC-2 family transporter protein
AKHFACLO_01722 3.24e-158 - - - S - - - ABC-2 family transporter protein
AKHFACLO_01723 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
AKHFACLO_01724 5.92e-299 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AKHFACLO_01725 1.72e-118 - - - - - - - -
AKHFACLO_01726 5.93e-187 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKHFACLO_01727 6.24e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKHFACLO_01729 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKHFACLO_01730 1.05e-89 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AKHFACLO_01731 1.35e-176 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
AKHFACLO_01732 1.08e-101 - - - S - - - Bacterial PH domain
AKHFACLO_01733 0.0 treS_1 - - G - - - Alpha amylase, catalytic domain
AKHFACLO_01735 5.47e-161 - - - - - - - -
AKHFACLO_01736 6.92e-171 - - - C - - - Putative TM nitroreductase
AKHFACLO_01737 1.25e-187 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
AKHFACLO_01738 4.75e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
AKHFACLO_01739 7.13e-56 - - - O - - - Glutaredoxin
AKHFACLO_01740 1.08e-108 - - - L ko:K07485 - ko00000 Transposase
AKHFACLO_01742 1.66e-238 - - - L - - - Transposase, Mutator family
AKHFACLO_01743 0.0 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AKHFACLO_01744 2.37e-213 - - - S - - - Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AKHFACLO_01745 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
AKHFACLO_01746 5.44e-91 - - - L ko:K07454 - ko00000 HNH endonuclease
AKHFACLO_01747 3.25e-307 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
AKHFACLO_01748 0.0 - - - EGP - - - Major Facilitator Superfamily
AKHFACLO_01749 9.1e-54 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
AKHFACLO_01750 4.33e-54 - - - L ko:K07483 - ko00000 Integrase core domain
AKHFACLO_01752 2.57e-231 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
AKHFACLO_01753 3.17e-207 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AKHFACLO_01754 2.15e-177 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
AKHFACLO_01755 3.12e-109 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
AKHFACLO_01756 1.99e-131 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
AKHFACLO_01757 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AKHFACLO_01758 9.32e-164 cseB - - T - - - Response regulator receiver domain protein
AKHFACLO_01759 5.91e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
AKHFACLO_01760 3.2e-93 umuD - - KT ko:K03503 - ko00000,ko01000,ko01002,ko03400 Peptidase S24-like
AKHFACLO_01761 1.33e-167 pyrE_1 - - S - - - Phosphoribosyl transferase domain
AKHFACLO_01762 2.33e-200 - - - T - - - Eukaryotic phosphomannomutase
AKHFACLO_01763 1.05e-85 - - - S - - - Zincin-like metallopeptidase
AKHFACLO_01764 0.0 - - - - - - - -
AKHFACLO_01765 0.0 - - - S - - - Glycosyl transferase, family 2
AKHFACLO_01766 2.82e-72 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
AKHFACLO_01767 0.0 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
AKHFACLO_01769 2.38e-223 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AKHFACLO_01770 5.63e-255 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
AKHFACLO_01771 2.19e-73 - - - S - - - Domain of unknown function (DUF4190)
AKHFACLO_01774 2.4e-65 - - - M - - - Lysin motif
AKHFACLO_01775 3.03e-166 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKHFACLO_01776 3.88e-213 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AKHFACLO_01777 1.13e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
AKHFACLO_01778 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKHFACLO_01779 7.67e-223 - - - - - - - -
AKHFACLO_01780 2.07e-156 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
AKHFACLO_01781 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
AKHFACLO_01782 6.69e-61 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
AKHFACLO_01783 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
AKHFACLO_01784 2.77e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
AKHFACLO_01785 8.19e-16 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
AKHFACLO_01786 3.55e-254 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
AKHFACLO_01787 3.86e-121 - - - S - - - RloB-like protein
AKHFACLO_01788 4.37e-289 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
AKHFACLO_01789 1.31e-268 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
AKHFACLO_01790 3.56e-145 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AKHFACLO_01791 7.61e-61 - - - E - - - Branched-chain amino acid transport protein (AzlD)
AKHFACLO_01792 2.11e-248 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
AKHFACLO_01793 2e-125 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
AKHFACLO_01794 5.46e-165 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
AKHFACLO_01795 2.03e-222 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKHFACLO_01796 3.06e-94 - - - O - - - OsmC-like protein
AKHFACLO_01797 1.08e-243 - - - T - - - Universal stress protein family
AKHFACLO_01798 4.19e-147 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
AKHFACLO_01799 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
AKHFACLO_01802 1.5e-15 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
AKHFACLO_01806 3.53e-230 - - - S ko:K21688 - ko00000 G5
AKHFACLO_01807 6.76e-78 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
AKHFACLO_01808 3.88e-152 - - - F - - - Domain of unknown function (DUF4916)
AKHFACLO_01809 2.84e-205 - - - I - - - Alpha/beta hydrolase family
AKHFACLO_01811 0.0 - - - S - - - L,D-transpeptidase catalytic domain
AKHFACLO_01812 9.32e-176 - - - L - - - IstB-like ATP binding protein
AKHFACLO_01813 4.57e-118 - - - L - - - Transposase
AKHFACLO_01814 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKHFACLO_01815 2.38e-73 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
AKHFACLO_01816 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
AKHFACLO_01817 2.06e-177 hflK - - O - - - prohibitin homologues
AKHFACLO_01818 2.31e-291 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
AKHFACLO_01819 1.96e-62 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
AKHFACLO_01820 1.03e-141 - - - - - - - -
AKHFACLO_01821 1.38e-239 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
AKHFACLO_01822 3.55e-280 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
AKHFACLO_01823 0.0 intA - - L - - - Phage integrase family
AKHFACLO_01824 9.55e-66 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
AKHFACLO_01825 1.78e-89 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
AKHFACLO_01826 2e-41 - - - - - - - -
AKHFACLO_01827 4.47e-199 - - - S - - - Domain of unknown function (DUF4357)
AKHFACLO_01828 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 modification (methylase) protein of type I restriction-modification system K03427
AKHFACLO_01829 1.1e-141 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
AKHFACLO_01830 0.0 - - - K - - - Putative DNA-binding domain
AKHFACLO_01831 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
AKHFACLO_01832 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
AKHFACLO_01833 1.6e-140 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
AKHFACLO_01834 3.54e-185 - - - S - - - Putative ABC-transporter type IV
AKHFACLO_01835 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKHFACLO_01836 0.000133 - - - K - - - Periplasmic binding protein LacI transcriptional regulator
AKHFACLO_01839 2.72e-236 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
AKHFACLO_01840 6.42e-112 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
AKHFACLO_01841 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
AKHFACLO_01842 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AKHFACLO_01843 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
AKHFACLO_01844 8.16e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKHFACLO_01845 4.39e-172 glnR - - KT - - - Transcriptional regulatory protein, C terminal
AKHFACLO_01846 5.6e-170 - - - - - - - -
AKHFACLO_01848 9.17e-131 mntP - - P - - - Probably functions as a manganese efflux pump
AKHFACLO_01849 3.13e-39 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
AKHFACLO_01850 1.68e-139 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
AKHFACLO_01851 4.1e-243 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
AKHFACLO_01852 1.22e-157 - - - U ko:K02025,ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AKHFACLO_01853 8.36e-158 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport systems inner membrane component
AKHFACLO_01854 4.37e-06 - - - - - - - -
AKHFACLO_01855 1.59e-159 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
AKHFACLO_01857 5.35e-271 - - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AKHFACLO_01859 8.29e-129 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
AKHFACLO_01860 9.3e-53 urtE - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AKHFACLO_01861 5.48e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKHFACLO_01862 8.99e-109 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AKHFACLO_01863 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
AKHFACLO_01864 4.31e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
AKHFACLO_01865 7.06e-132 - - - K - - - Transcriptional regulator C-terminal region
AKHFACLO_01866 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
AKHFACLO_01867 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
AKHFACLO_01869 1.15e-234 - - - S - - - Protein of unknown function (DUF559)
AKHFACLO_01870 2.52e-160 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AKHFACLO_01871 4.84e-128 - - - - ko:K03646 - ko00000,ko02000 -
AKHFACLO_01872 2.8e-27 - - - - - - - -
AKHFACLO_01873 4.45e-85 - - - L ko:K07483 - ko00000 Integrase core domain
AKHFACLO_01874 2.45e-49 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
AKHFACLO_01875 1.11e-148 - - - K - - - WHG domain
AKHFACLO_01876 7.13e-143 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
AKHFACLO_01877 9.35e-140 - - - - - - - -
AKHFACLO_01878 1.35e-193 - - - L ko:K07454 - ko00000 HNH endonuclease
AKHFACLO_01879 0.0 - - - I - - - PAP2 superfamily
AKHFACLO_01880 4.16e-131 - - - K - - - helix_turn_helix, Lux Regulon
AKHFACLO_01881 0.0 - - - T - - - Histidine kinase
AKHFACLO_01882 1.47e-169 - - - M - - - Mechanosensitive ion channel
AKHFACLO_01883 1.51e-153 - - - K - - - Bacterial regulatory proteins, tetR family
AKHFACLO_01884 3.98e-289 - - - S - - - Psort location Cytoplasmic, score 8.87
AKHFACLO_01885 2.9e-296 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
AKHFACLO_01886 7.37e-156 - - - - - - - -
AKHFACLO_01887 2.95e-32 - - - M - - - Belongs to the glycosyl hydrolase 28 family
AKHFACLO_01889 1.75e-43 - - - S ko:K06889 - ko00000 alpha beta
AKHFACLO_01890 2.94e-15 - - - K - - - Transcriptional regulator
AKHFACLO_01891 1.01e-71 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKHFACLO_01892 4.59e-290 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
AKHFACLO_01893 0.0 - - - L - - - DNA helicase
AKHFACLO_01894 8.85e-118 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
AKHFACLO_01896 0.0 - - - - - - - -
AKHFACLO_01897 3.83e-259 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKHFACLO_01898 2.85e-141 vpr - - O - - - Subtilase family
AKHFACLO_01899 3e-80 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
AKHFACLO_01900 2.78e-170 tmp1 - - S - - - Domain of unknown function (DUF4391)
AKHFACLO_01901 7.18e-192 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
AKHFACLO_01902 0.0 - - - OP - - - Sulfurtransferase TusA
AKHFACLO_01903 1.11e-232 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
AKHFACLO_01904 8.17e-204 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Phosphotransferase enzyme family
AKHFACLO_01905 1.74e-18 - - - L - - - PFAM Integrase catalytic
AKHFACLO_01906 2.6e-185 istB - - L - - - IstB-like ATP binding protein
AKHFACLO_01907 3.8e-109 - - - L - - - Winged helix-turn helix
AKHFACLO_01908 3.41e-172 - - - V - - - HNH endonuclease
AKHFACLO_01909 2.89e-170 - - - S - - - Adenine-specific methyltransferase EcoRI
AKHFACLO_01910 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
AKHFACLO_01911 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
AKHFACLO_01912 1.18e-228 - - - S - - - CHAP domain
AKHFACLO_01913 7.39e-275 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AKHFACLO_01914 4.6e-53 - - - - - - - -
AKHFACLO_01915 6.51e-288 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
AKHFACLO_01916 9.33e-153 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
AKHFACLO_01918 5.27e-196 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKHFACLO_01919 2.89e-224 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
AKHFACLO_01920 3.93e-237 - - - L - - - HTH-like domain
AKHFACLO_01921 5.86e-64 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
AKHFACLO_01922 2.69e-82 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
AKHFACLO_01923 6.49e-163 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AKHFACLO_01924 1.09e-37 istB - - L - - - IstB-like ATP binding protein
AKHFACLO_01925 2.49e-228 - - - L - - - Phage integrase family
AKHFACLO_01926 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
AKHFACLO_01927 2.42e-133 - - - L - - - Belongs to the 'phage' integrase family
AKHFACLO_01928 1.16e-138 - - - - - - - -
AKHFACLO_01932 1.56e-191 - - - L - - - PFAM Integrase catalytic
AKHFACLO_01933 3.53e-59 - - - L - - - Transposase
AKHFACLO_01935 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
AKHFACLO_01936 1.41e-240 - - - M - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AKHFACLO_01937 4.68e-40 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
AKHFACLO_01938 6.22e-22 int8 - - L - - - Phage integrase family
AKHFACLO_01939 3.16e-56 int8 - - L - - - Phage integrase family
AKHFACLO_01940 0.0 pccB - - I - - - Carboxyl transferase domain
AKHFACLO_01941 4.02e-21 - - - L - - - Transposase, Mutator family
AKHFACLO_01942 3.67e-82 - - - D - - - MobA/MobL family
AKHFACLO_01943 3.32e-83 - - - - - - - -
AKHFACLO_01946 3.03e-16 - - - - - - - -
AKHFACLO_01947 1.04e-49 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
AKHFACLO_01948 5.58e-33 - - - S - - - Adenine-specific methyltransferase EcoRI
AKHFACLO_01949 1.13e-53 - - - - - - - -
AKHFACLO_01950 6.8e-89 - - - L - - - Transposase, Mutator family
AKHFACLO_01951 8.33e-184 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)