ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GBCLOFCM_00001 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GBCLOFCM_00002 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBCLOFCM_00003 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
GBCLOFCM_00004 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GBCLOFCM_00005 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GBCLOFCM_00006 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GBCLOFCM_00007 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GBCLOFCM_00008 9.26e-98 - - - S - - - Bacterial PH domain
GBCLOFCM_00009 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
GBCLOFCM_00010 4.62e-190 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GBCLOFCM_00011 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
GBCLOFCM_00012 1.6e-140 yyaD - - S - - - Membrane
GBCLOFCM_00013 1.72e-74 yyaD - - S - - - Membrane
GBCLOFCM_00014 2.57e-37 yyzM - - S - - - protein conserved in bacteria
GBCLOFCM_00015 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GBCLOFCM_00016 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GBCLOFCM_00017 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GBCLOFCM_00018 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GBCLOFCM_00019 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GBCLOFCM_00020 3.43e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GBCLOFCM_00021 2.49e-229 ccpB - - K - - - Transcriptional regulator
GBCLOFCM_00022 3.3e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_00023 7.68e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
GBCLOFCM_00024 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
GBCLOFCM_00025 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
GBCLOFCM_00026 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
GBCLOFCM_00027 1.34e-205 - - - EG - - - EamA-like transporter family
GBCLOFCM_00028 1.34e-88 - - - K - - - MerR HTH family regulatory protein
GBCLOFCM_00029 2.16e-07 - - - S - - - Putative amidase domain
GBCLOFCM_00031 9.19e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
GBCLOFCM_00032 8.09e-314 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_00033 8.62e-137 yyaP - - H - - - RibD C-terminal domain
GBCLOFCM_00034 1.5e-85 - - - S - - - YjbR
GBCLOFCM_00035 6.2e-92 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
GBCLOFCM_00036 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
GBCLOFCM_00037 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
GBCLOFCM_00038 4.54e-100 yybA - - K - - - transcriptional
GBCLOFCM_00039 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
GBCLOFCM_00040 5.79e-96 yybC - - - - - - -
GBCLOFCM_00041 4.58e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
GBCLOFCM_00042 4.56e-211 yybE - - K - - - Transcriptional regulator
GBCLOFCM_00043 2.04e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_00044 1.98e-162 yybG - - S - - - Pentapeptide repeat-containing protein
GBCLOFCM_00045 1.38e-84 - - - S - - - SnoaL-like domain
GBCLOFCM_00046 7.14e-184 - - - - - - - -
GBCLOFCM_00047 5.26e-122 - - - K - - - TipAS antibiotic-recognition domain
GBCLOFCM_00048 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_00050 3.73e-89 - - - - - - - -
GBCLOFCM_00051 1.34e-207 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
GBCLOFCM_00052 1.3e-87 yybR - - K - - - Transcriptional regulator
GBCLOFCM_00053 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
GBCLOFCM_00055 1.5e-204 yybS - - S - - - membrane
GBCLOFCM_00056 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GBCLOFCM_00057 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GBCLOFCM_00058 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GBCLOFCM_00059 2.83e-281 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
GBCLOFCM_00060 1.89e-22 yycC - - K - - - YycC-like protein
GBCLOFCM_00062 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GBCLOFCM_00063 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GBCLOFCM_00064 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_00065 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBCLOFCM_00070 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00071 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00072 0.0 yycH - - S - - - protein conserved in bacteria
GBCLOFCM_00073 9.86e-200 yycI - - S - - - protein conserved in bacteria
GBCLOFCM_00074 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GBCLOFCM_00075 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBCLOFCM_00076 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
GBCLOFCM_00077 2.66e-97 - - - S - - - Peptidase propeptide and YPEB domain
GBCLOFCM_00078 0.000194 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00079 1.47e-30 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
GBCLOFCM_00080 1.87e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GBCLOFCM_00081 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GBCLOFCM_00082 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
GBCLOFCM_00083 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GBCLOFCM_00084 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GBCLOFCM_00086 8.7e-239 - - - S - - - aspartate phosphatase
GBCLOFCM_00087 3.69e-111 yycN - - K - - - Acetyltransferase
GBCLOFCM_00088 4.81e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GBCLOFCM_00089 3.42e-163 yycP - - - - - - -
GBCLOFCM_00090 2.11e-67 yycP - - - - - - -
GBCLOFCM_00091 2.16e-39 yycQ - - S - - - Protein of unknown function (DUF2651)
GBCLOFCM_00093 1.05e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GBCLOFCM_00094 2.22e-80 - - - - - - - -
GBCLOFCM_00096 1.43e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GBCLOFCM_00097 1.2e-67 - - - - - - - -
GBCLOFCM_00098 3.07e-44 - - - - - - - -
GBCLOFCM_00100 9.09e-148 - - - D - - - Protein of unknown function (DUF3732)
GBCLOFCM_00101 5.95e-220 - - - D - - - Protein of unknown function (DUF3732)
GBCLOFCM_00102 1.62e-136 - - - K - - - Transcriptional regulator
GBCLOFCM_00104 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
GBCLOFCM_00105 5.87e-24 - - - - - - - -
GBCLOFCM_00106 8.29e-161 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_00107 1.6e-34 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
GBCLOFCM_00108 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GBCLOFCM_00109 1.11e-237 - - - S - - - Polysaccharide pyruvyl transferase
GBCLOFCM_00110 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
GBCLOFCM_00111 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
GBCLOFCM_00112 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GBCLOFCM_00113 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GBCLOFCM_00114 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GBCLOFCM_00115 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
GBCLOFCM_00116 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GBCLOFCM_00117 1.21e-243 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
GBCLOFCM_00118 1.45e-151 yxaC - - M - - - effector of murein hydrolase
GBCLOFCM_00119 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_00120 2.9e-253 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00121 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GBCLOFCM_00122 3.65e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
GBCLOFCM_00123 1.08e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GBCLOFCM_00124 4.03e-99 yxaI - - S - - - membrane protein domain
GBCLOFCM_00125 3.24e-82 - - - S - - - Family of unknown function (DUF5391)
GBCLOFCM_00126 5.06e-114 yxaL - - S - - - PQQ-like domain
GBCLOFCM_00127 1.63e-41 yxaI - - S - - - membrane protein domain
GBCLOFCM_00128 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GBCLOFCM_00129 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
GBCLOFCM_00130 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_00132 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
GBCLOFCM_00133 3.41e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GBCLOFCM_00134 8.67e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
GBCLOFCM_00136 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GBCLOFCM_00137 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GBCLOFCM_00138 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GBCLOFCM_00139 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GBCLOFCM_00140 3.52e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GBCLOFCM_00141 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GBCLOFCM_00142 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GBCLOFCM_00143 4.01e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
GBCLOFCM_00144 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GBCLOFCM_00145 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
GBCLOFCM_00146 1.54e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GBCLOFCM_00147 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GBCLOFCM_00148 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00149 1.63e-232 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00150 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00151 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GBCLOFCM_00152 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
GBCLOFCM_00153 1.23e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GBCLOFCM_00154 1.6e-89 - - - - - - - -
GBCLOFCM_00155 7.57e-28 yxeD - - - - - - -
GBCLOFCM_00156 7.32e-42 yxeE - - - - - - -
GBCLOFCM_00159 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
GBCLOFCM_00160 1.84e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
GBCLOFCM_00161 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_00162 3.63e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_00163 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GBCLOFCM_00164 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GBCLOFCM_00165 3.94e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00166 6.79e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GBCLOFCM_00167 2.06e-314 yxeQ - - S - - - MmgE/PrpD family
GBCLOFCM_00168 9.4e-257 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
GBCLOFCM_00169 1.48e-193 - - - S - - - Domain of Unknown Function (DUF1206)
GBCLOFCM_00170 4.97e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GBCLOFCM_00171 1.09e-135 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GBCLOFCM_00172 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GBCLOFCM_00173 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
GBCLOFCM_00174 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GBCLOFCM_00175 1.39e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GBCLOFCM_00176 2.61e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
GBCLOFCM_00177 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GBCLOFCM_00178 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
GBCLOFCM_00179 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GBCLOFCM_00180 5.13e-16 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
GBCLOFCM_00182 4.54e-13 - - - S - - - Oxidoreductase
GBCLOFCM_00183 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GBCLOFCM_00184 7.79e-35 - - - S - - - Domain of unknown function (DUF5082)
GBCLOFCM_00185 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
GBCLOFCM_00186 6.97e-263 - - - S - - - nuclease activity
GBCLOFCM_00187 1.1e-67 - - - S - - - nuclease activity
GBCLOFCM_00188 1.08e-63 - - - - - - - -
GBCLOFCM_00189 8.25e-69 - - - - - - - -
GBCLOFCM_00190 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_00191 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GBCLOFCM_00192 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
GBCLOFCM_00193 7.53e-156 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
GBCLOFCM_00194 2.01e-162 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_00195 2.82e-208 yxxF - - EG - - - EamA-like transporter family
GBCLOFCM_00196 6.41e-53 - - - - - - - -
GBCLOFCM_00197 2.19e-106 yxiI - - S - - - Protein of unknown function (DUF2716)
GBCLOFCM_00198 2.86e-58 yxiJ - - S - - - YxiJ-like protein
GBCLOFCM_00201 1.14e-79 - - - S - - - Protein of unknown function (DUF2812)
GBCLOFCM_00202 1.08e-69 - - - K - - - Transcriptional regulator PadR-like family
GBCLOFCM_00203 3.67e-276 - - - E - - - GDSL-like Lipase/Acylhydrolase
GBCLOFCM_00204 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GBCLOFCM_00205 6.57e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
GBCLOFCM_00206 2.42e-139 - - - - - - - -
GBCLOFCM_00207 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GBCLOFCM_00208 3.06e-184 bglS - - M - - - licheninase activity
GBCLOFCM_00209 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GBCLOFCM_00210 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GBCLOFCM_00211 2.28e-63 yxiS - - - - - - -
GBCLOFCM_00212 4.89e-132 - - - T - - - Domain of unknown function (DUF4163)
GBCLOFCM_00213 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GBCLOFCM_00214 3.44e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
GBCLOFCM_00215 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
GBCLOFCM_00216 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GBCLOFCM_00217 2.41e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GBCLOFCM_00218 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GBCLOFCM_00219 1.55e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GBCLOFCM_00220 7.09e-246 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GBCLOFCM_00221 4.83e-18 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GBCLOFCM_00222 1.43e-111 yxjI - - S - - - LURP-one-related
GBCLOFCM_00225 4.49e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GBCLOFCM_00226 7.4e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
GBCLOFCM_00227 1.37e-258 - - - T - - - Signal transduction histidine kinase
GBCLOFCM_00228 1.89e-100 - - - S - - - Protein of unknown function (DUF1453)
GBCLOFCM_00229 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GBCLOFCM_00230 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
GBCLOFCM_00231 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GBCLOFCM_00232 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GBCLOFCM_00233 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
GBCLOFCM_00234 1.4e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_00235 7.49e-199 yxkH - - G - - - Polysaccharide deacetylase
GBCLOFCM_00237 0.0 - - - O - - - Peptidase family M48
GBCLOFCM_00238 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
GBCLOFCM_00239 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GBCLOFCM_00240 6.73e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
GBCLOFCM_00241 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
GBCLOFCM_00242 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
GBCLOFCM_00243 4.36e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GBCLOFCM_00244 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
GBCLOFCM_00245 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_00246 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
GBCLOFCM_00247 2.92e-42 - - - - - - - -
GBCLOFCM_00248 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
GBCLOFCM_00249 5.52e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00250 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GBCLOFCM_00251 3.02e-275 yxlH - - EGP - - - Major Facilitator Superfamily
GBCLOFCM_00252 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GBCLOFCM_00253 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GBCLOFCM_00254 8.94e-28 yxzF - - - - - - -
GBCLOFCM_00255 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GBCLOFCM_00256 1.18e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
GBCLOFCM_00257 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GBCLOFCM_00258 2.39e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_00259 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GBCLOFCM_00260 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GBCLOFCM_00261 2.39e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00262 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GBCLOFCM_00263 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_00264 4.63e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
GBCLOFCM_00265 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_00266 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GBCLOFCM_00267 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
GBCLOFCM_00268 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
GBCLOFCM_00269 3.5e-103 - - - EGP - - - Permeases of the major facilitator superfamily
GBCLOFCM_00270 3.13e-44 - - - EGP - - - Permeases of the major facilitator superfamily
GBCLOFCM_00271 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GBCLOFCM_00272 1.24e-87 - - - K - - - Helix-turn-helix XRE-family like proteins
GBCLOFCM_00273 4.55e-06 - - - K - - - Helix-turn-helix domain
GBCLOFCM_00274 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
GBCLOFCM_00275 9.04e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBCLOFCM_00276 1.25e-114 ywaE - - K - - - Transcriptional regulator
GBCLOFCM_00277 8.23e-157 ywaF - - S - - - Integral membrane protein
GBCLOFCM_00278 4.41e-215 gspA - - M - - - General stress
GBCLOFCM_00279 1.06e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GBCLOFCM_00280 6.87e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_00281 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GBCLOFCM_00282 7.07e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GBCLOFCM_00283 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
GBCLOFCM_00284 4.67e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
GBCLOFCM_00285 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
GBCLOFCM_00286 4.31e-277 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
GBCLOFCM_00287 1.21e-143 ywbG - - M - - - effector of murein hydrolase
GBCLOFCM_00288 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GBCLOFCM_00289 1.56e-202 ywbI - - K - - - Transcriptional regulator
GBCLOFCM_00290 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GBCLOFCM_00291 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GBCLOFCM_00292 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
GBCLOFCM_00293 6.92e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
GBCLOFCM_00294 8.78e-303 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
GBCLOFCM_00295 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GBCLOFCM_00296 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBCLOFCM_00297 1.75e-61 ywcB - - S - - - Protein of unknown function, DUF485
GBCLOFCM_00299 3.42e-158 ywcC - - K - - - transcriptional regulator
GBCLOFCM_00300 3.33e-77 gtcA - - S - - - GtrA-like protein
GBCLOFCM_00301 1.12e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GBCLOFCM_00302 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GBCLOFCM_00303 5.11e-49 ydaS - - S - - - membrane
GBCLOFCM_00304 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GBCLOFCM_00305 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBCLOFCM_00306 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GBCLOFCM_00307 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GBCLOFCM_00308 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
GBCLOFCM_00309 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GBCLOFCM_00310 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
GBCLOFCM_00311 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_00312 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GBCLOFCM_00314 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GBCLOFCM_00315 2.79e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
GBCLOFCM_00316 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_00317 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GBCLOFCM_00318 6.19e-39 ywdA - - - - - - -
GBCLOFCM_00319 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GBCLOFCM_00320 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GBCLOFCM_00321 4.18e-143 ywdD - - - - - - -
GBCLOFCM_00323 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
GBCLOFCM_00324 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBCLOFCM_00325 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GBCLOFCM_00326 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
GBCLOFCM_00327 1.65e-293 ywdJ - - F - - - Xanthine uracil
GBCLOFCM_00328 5.78e-68 ywdK - - S - - - small membrane protein
GBCLOFCM_00329 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GBCLOFCM_00330 8.08e-187 spsA - - M - - - Spore Coat
GBCLOFCM_00331 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
GBCLOFCM_00332 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
GBCLOFCM_00333 8.17e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
GBCLOFCM_00334 1.6e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
GBCLOFCM_00335 3.14e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
GBCLOFCM_00336 1.92e-238 spsG - - M - - - Spore Coat
GBCLOFCM_00337 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GBCLOFCM_00338 7.47e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GBCLOFCM_00339 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GBCLOFCM_00340 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
GBCLOFCM_00341 3.7e-101 - - - - - - - -
GBCLOFCM_00342 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GBCLOFCM_00343 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GBCLOFCM_00344 0.0 rocB - - E - - - arginine degradation protein
GBCLOFCM_00345 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GBCLOFCM_00346 4.44e-274 ywfA - - EGP - - - -transporter
GBCLOFCM_00347 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GBCLOFCM_00348 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GBCLOFCM_00349 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_00350 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GBCLOFCM_00351 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
GBCLOFCM_00352 2.12e-295 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
GBCLOFCM_00353 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_00354 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
GBCLOFCM_00355 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
GBCLOFCM_00356 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_00357 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GBCLOFCM_00358 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
GBCLOFCM_00359 7.66e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
GBCLOFCM_00360 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
GBCLOFCM_00361 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
GBCLOFCM_00362 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
GBCLOFCM_00363 8.67e-101 yffB - - K - - - Transcriptional regulator
GBCLOFCM_00364 1.41e-302 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
GBCLOFCM_00366 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBCLOFCM_00367 1.45e-93 ywhA - - K - - - Transcriptional regulator
GBCLOFCM_00368 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
GBCLOFCM_00369 3.29e-154 ywhC - - S - - - Peptidase family M50
GBCLOFCM_00370 7.83e-123 ywhD - - S - - - YwhD family
GBCLOFCM_00371 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GBCLOFCM_00372 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GBCLOFCM_00373 6.02e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GBCLOFCM_00374 2.17e-37 - - - S - - - Aminoacyl-tRNA editing domain
GBCLOFCM_00376 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GBCLOFCM_00377 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
GBCLOFCM_00378 9.08e-317 ywhL - - CO - - - amine dehydrogenase activity
GBCLOFCM_00380 1.89e-314 - - - L - - - Peptidase, M16
GBCLOFCM_00381 5.94e-277 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
GBCLOFCM_00382 2.81e-296 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
GBCLOFCM_00383 1.23e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GBCLOFCM_00385 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
GBCLOFCM_00386 3.71e-12 - - - S - - - Bacteriocin subtilosin A
GBCLOFCM_00387 4.64e-96 ywiB - - S - - - protein conserved in bacteria
GBCLOFCM_00388 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GBCLOFCM_00389 1.7e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GBCLOFCM_00390 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
GBCLOFCM_00391 1.84e-179 ywiC - - S - - - YwiC-like protein
GBCLOFCM_00392 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
GBCLOFCM_00393 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GBCLOFCM_00394 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
GBCLOFCM_00395 1.95e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
GBCLOFCM_00396 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
GBCLOFCM_00397 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBCLOFCM_00398 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GBCLOFCM_00399 1.57e-123 ywjB - - H - - - RibD C-terminal domain
GBCLOFCM_00400 1.32e-57 ywjC - - - - - - -
GBCLOFCM_00401 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GBCLOFCM_00402 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GBCLOFCM_00403 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
GBCLOFCM_00404 2.2e-91 ywjF - - C - - - COG0247 Fe-S oxidoreductase
GBCLOFCM_00405 4.95e-268 acdA - - I - - - acyl-CoA dehydrogenase
GBCLOFCM_00406 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GBCLOFCM_00407 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GBCLOFCM_00408 2.24e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
GBCLOFCM_00409 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
GBCLOFCM_00410 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
GBCLOFCM_00411 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GBCLOFCM_00412 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBCLOFCM_00413 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
GBCLOFCM_00414 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GBCLOFCM_00415 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
GBCLOFCM_00416 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GBCLOFCM_00417 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GBCLOFCM_00418 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
GBCLOFCM_00419 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GBCLOFCM_00420 1.39e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_00421 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GBCLOFCM_00422 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GBCLOFCM_00424 7.97e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
GBCLOFCM_00425 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
GBCLOFCM_00426 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
GBCLOFCM_00427 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GBCLOFCM_00428 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
GBCLOFCM_00429 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBCLOFCM_00430 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
GBCLOFCM_00431 7.13e-123 ywlG - - S - - - Belongs to the UPF0340 family
GBCLOFCM_00432 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBCLOFCM_00433 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GBCLOFCM_00434 2.23e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
GBCLOFCM_00435 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GBCLOFCM_00436 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBCLOFCM_00437 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GBCLOFCM_00438 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBCLOFCM_00439 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GBCLOFCM_00440 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GBCLOFCM_00441 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GBCLOFCM_00442 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GBCLOFCM_00443 6.12e-115 ywmA - - - - - - -
GBCLOFCM_00444 4.54e-45 ywzB - - S - - - membrane
GBCLOFCM_00445 6.32e-170 ywmB - - S - - - TATA-box binding
GBCLOFCM_00446 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBCLOFCM_00447 3.27e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
GBCLOFCM_00448 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GBCLOFCM_00449 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GBCLOFCM_00451 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GBCLOFCM_00452 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GBCLOFCM_00453 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GBCLOFCM_00454 1.26e-109 ywmF - - S - - - Peptidase M50
GBCLOFCM_00455 1.84e-20 csbD - - K - - - CsbD-like
GBCLOFCM_00456 3.46e-05 urtA - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
GBCLOFCM_00457 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
GBCLOFCM_00458 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
GBCLOFCM_00459 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GBCLOFCM_00460 4.58e-85 ywnA - - K - - - Transcriptional regulator
GBCLOFCM_00461 3.72e-50 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
GBCLOFCM_00462 4.47e-78 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
GBCLOFCM_00463 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
GBCLOFCM_00464 1.33e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
GBCLOFCM_00465 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBCLOFCM_00466 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
GBCLOFCM_00467 5.2e-21 ywnC - - S - - - Family of unknown function (DUF5362)
GBCLOFCM_00468 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
GBCLOFCM_00469 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GBCLOFCM_00470 1.65e-40 - - - L - - - Restriction endonuclease BamHI
GBCLOFCM_00471 2.47e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
GBCLOFCM_00472 2.35e-152 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GBCLOFCM_00473 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
GBCLOFCM_00474 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
GBCLOFCM_00475 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
GBCLOFCM_00476 4.15e-100 - - - - - - - -
GBCLOFCM_00477 1.04e-133 yjgF - - Q - - - Isochorismatase family
GBCLOFCM_00478 3.63e-305 ywoD - - EGP - - - Major facilitator superfamily
GBCLOFCM_00479 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
GBCLOFCM_00480 1.45e-312 ywoF - - P - - - Right handed beta helix region
GBCLOFCM_00481 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_00482 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
GBCLOFCM_00483 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
GBCLOFCM_00484 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
GBCLOFCM_00485 1.02e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GBCLOFCM_00486 1.6e-179 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GBCLOFCM_00487 9.03e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
GBCLOFCM_00488 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GBCLOFCM_00489 4.62e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GBCLOFCM_00490 0.0 ywpD - - T - - - Histidine kinase
GBCLOFCM_00491 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
GBCLOFCM_00492 0.0 - - - M - - - cell wall anchor domain
GBCLOFCM_00493 0.0 - - - M - - - cell wall anchor domain
GBCLOFCM_00494 1.01e-107 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GBCLOFCM_00495 2.53e-88 ywpF - - S - - - YwpF-like protein
GBCLOFCM_00496 1.76e-86 ywpG - - - - - - -
GBCLOFCM_00497 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
GBCLOFCM_00498 1.14e-178 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GBCLOFCM_00499 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GBCLOFCM_00500 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GBCLOFCM_00501 0.0 ywqB - - S - - - SWIM zinc finger
GBCLOFCM_00502 3.6e-25 - - - - - - - -
GBCLOFCM_00503 3.08e-162 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
GBCLOFCM_00504 1.22e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GBCLOFCM_00505 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
GBCLOFCM_00506 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GBCLOFCM_00507 7.79e-192 ywqG - - S - - - Domain of unknown function (DUF1963)
GBCLOFCM_00509 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
GBCLOFCM_00510 2.89e-302 ywqJ - - S - - - Pre-toxin TG
GBCLOFCM_00512 7.19e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GBCLOFCM_00513 2.34e-209 - - - K - - - Transcriptional regulator
GBCLOFCM_00514 2.91e-127 ywqN - - S - - - NAD(P)H-dependent
GBCLOFCM_00516 7.11e-104 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
GBCLOFCM_00517 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
GBCLOFCM_00518 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GBCLOFCM_00519 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GBCLOFCM_00520 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
GBCLOFCM_00521 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBCLOFCM_00522 2.17e-16 - - - - - - - -
GBCLOFCM_00523 4.57e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
GBCLOFCM_00524 1.35e-180 cotB - - - ko:K06325 - ko00000 -
GBCLOFCM_00525 9.09e-164 ywrJ - - - - - - -
GBCLOFCM_00526 3.25e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GBCLOFCM_00527 3.36e-218 alsR - - K - - - LysR substrate binding domain
GBCLOFCM_00528 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GBCLOFCM_00529 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
GBCLOFCM_00530 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
GBCLOFCM_00531 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
GBCLOFCM_00532 2.05e-121 batE - - T - - - Sh3 type 3 domain protein
GBCLOFCM_00533 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
GBCLOFCM_00534 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GBCLOFCM_00535 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GBCLOFCM_00536 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GBCLOFCM_00537 3.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBCLOFCM_00538 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
GBCLOFCM_00539 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
GBCLOFCM_00540 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
GBCLOFCM_00541 1.56e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GBCLOFCM_00542 4.62e-29 ywtC - - - - - - -
GBCLOFCM_00543 1.11e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GBCLOFCM_00544 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GBCLOFCM_00545 1.22e-221 ywtF_2 - - K - - - Transcriptional regulator
GBCLOFCM_00546 6.46e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GBCLOFCM_00547 4.98e-260 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
GBCLOFCM_00548 2.5e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GBCLOFCM_00549 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GBCLOFCM_00550 7.82e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GBCLOFCM_00551 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GBCLOFCM_00552 5.02e-225 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GBCLOFCM_00553 1.34e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GBCLOFCM_00554 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
GBCLOFCM_00555 1.7e-133 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
GBCLOFCM_00556 8.85e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GBCLOFCM_00557 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GBCLOFCM_00558 6.18e-42 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
GBCLOFCM_00559 1.2e-170 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GBCLOFCM_00560 3.03e-263 - - - M - - - Glycosyltransferase like family 2
GBCLOFCM_00561 9.99e-33 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GBCLOFCM_00562 2.16e-153 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GBCLOFCM_00563 1.8e-179 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GBCLOFCM_00564 4.79e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
GBCLOFCM_00565 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GBCLOFCM_00566 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GBCLOFCM_00568 1.04e-12 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GBCLOFCM_00569 5.07e-85 - - - M - - - Glycosyl transferases group 1
GBCLOFCM_00570 1.06e-103 - - - M - - - Glycosyltransferase like family 2
GBCLOFCM_00571 1.56e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GBCLOFCM_00572 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GBCLOFCM_00573 4.58e-16 - - - - - - - -
GBCLOFCM_00574 0.0 lytB - - D - - - Stage II sporulation protein
GBCLOFCM_00575 2.92e-263 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GBCLOFCM_00576 2.58e-46 - - - M - - - Glycosyltransferase like family 2
GBCLOFCM_00577 9.08e-27 - - - M - - - Glycosyltransferase like family 2
GBCLOFCM_00578 7.2e-104 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GBCLOFCM_00579 1.2e-314 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_00580 4.66e-278 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
GBCLOFCM_00581 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GBCLOFCM_00582 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
GBCLOFCM_00583 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
GBCLOFCM_00584 1.48e-136 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GBCLOFCM_00585 8.7e-299 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
GBCLOFCM_00586 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GBCLOFCM_00587 8.05e-225 yvhJ - - K - - - Transcriptional regulator
GBCLOFCM_00588 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
GBCLOFCM_00589 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GBCLOFCM_00590 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_00591 2.15e-199 degV - - S - - - protein conserved in bacteria
GBCLOFCM_00592 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GBCLOFCM_00593 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
GBCLOFCM_00594 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
GBCLOFCM_00595 1.83e-96 yvyF - - S - - - flagellar protein
GBCLOFCM_00596 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
GBCLOFCM_00597 3.5e-102 yvyG - - NOU - - - FlgN protein
GBCLOFCM_00598 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
GBCLOFCM_00599 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
GBCLOFCM_00600 4.19e-93 yviE - - - - - - -
GBCLOFCM_00601 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GBCLOFCM_00602 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GBCLOFCM_00603 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GBCLOFCM_00604 7.81e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
GBCLOFCM_00605 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GBCLOFCM_00606 2.45e-89 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
GBCLOFCM_00607 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
GBCLOFCM_00608 9.14e-88 - - - - - - - -
GBCLOFCM_00609 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GBCLOFCM_00610 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GBCLOFCM_00611 1.45e-258 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GBCLOFCM_00612 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GBCLOFCM_00613 9.92e-35 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GBCLOFCM_00614 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
GBCLOFCM_00615 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GBCLOFCM_00616 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GBCLOFCM_00617 1.38e-73 swrA - - S - - - Swarming motility protein
GBCLOFCM_00618 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBCLOFCM_00619 5.01e-294 yvkA - - P - - - -transporter
GBCLOFCM_00620 9.63e-130 yvkB - - K - - - Transcriptional regulator
GBCLOFCM_00621 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
GBCLOFCM_00622 2.54e-42 csbA - - S - - - protein conserved in bacteria
GBCLOFCM_00623 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GBCLOFCM_00624 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GBCLOFCM_00625 2.02e-101 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GBCLOFCM_00626 2.25e-45 yvkN - - - - - - -
GBCLOFCM_00627 8.09e-65 yvlA - - - - - - -
GBCLOFCM_00628 5.8e-221 yvlB - - S - - - Putative adhesin
GBCLOFCM_00629 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GBCLOFCM_00630 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
GBCLOFCM_00631 6.05e-272 yvmA - - EGP - - - Major Facilitator Superfamily
GBCLOFCM_00632 8.46e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_00633 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
GBCLOFCM_00634 1.88e-292 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GBCLOFCM_00635 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_00636 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
GBCLOFCM_00637 1.75e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
GBCLOFCM_00638 3.66e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GBCLOFCM_00639 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GBCLOFCM_00640 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GBCLOFCM_00641 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GBCLOFCM_00642 6.16e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
GBCLOFCM_00643 1.76e-152 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GBCLOFCM_00644 8.03e-107 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GBCLOFCM_00645 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
GBCLOFCM_00646 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
GBCLOFCM_00647 2.82e-280 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GBCLOFCM_00648 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GBCLOFCM_00649 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBCLOFCM_00650 3.35e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GBCLOFCM_00651 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GBCLOFCM_00652 3.95e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GBCLOFCM_00653 2.79e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GBCLOFCM_00654 3.05e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
GBCLOFCM_00655 8.43e-86 - - - - - - - -
GBCLOFCM_00656 7.08e-109 - - - - - - - -
GBCLOFCM_00657 0.0 - - - - - - - -
GBCLOFCM_00659 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GBCLOFCM_00660 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
GBCLOFCM_00661 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
GBCLOFCM_00662 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GBCLOFCM_00663 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GBCLOFCM_00664 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GBCLOFCM_00665 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GBCLOFCM_00666 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GBCLOFCM_00667 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
GBCLOFCM_00668 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
GBCLOFCM_00669 1.32e-43 - - - - - - - -
GBCLOFCM_00670 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00671 2.78e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
GBCLOFCM_00672 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00673 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GBCLOFCM_00674 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBCLOFCM_00675 4.36e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GBCLOFCM_00676 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GBCLOFCM_00677 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
GBCLOFCM_00678 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GBCLOFCM_00679 1.27e-220 yvdE - - K - - - Transcriptional regulator
GBCLOFCM_00680 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
GBCLOFCM_00681 4.19e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GBCLOFCM_00682 5e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GBCLOFCM_00683 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GBCLOFCM_00684 3.12e-194 malA - - S - - - Protein of unknown function (DUF1189)
GBCLOFCM_00685 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
GBCLOFCM_00686 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GBCLOFCM_00687 8.13e-142 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GBCLOFCM_00688 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GBCLOFCM_00690 9.45e-234 - - - S - - - Patatin-like phospholipase
GBCLOFCM_00691 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
GBCLOFCM_00692 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
GBCLOFCM_00693 4.36e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
GBCLOFCM_00694 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GBCLOFCM_00695 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
GBCLOFCM_00696 0.0 ybeC - - E - - - amino acid
GBCLOFCM_00697 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GBCLOFCM_00698 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
GBCLOFCM_00699 0.0 pbpE - - V - - - Beta-lactamase
GBCLOFCM_00700 8.37e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GBCLOFCM_00701 4.27e-63 - - - S - - - Protein of unknown function (DUF3237)
GBCLOFCM_00702 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GBCLOFCM_00704 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
GBCLOFCM_00705 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
GBCLOFCM_00706 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
GBCLOFCM_00707 4.59e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GBCLOFCM_00708 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GBCLOFCM_00709 1.57e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
GBCLOFCM_00710 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
GBCLOFCM_00711 2.4e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GBCLOFCM_00712 2.95e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
GBCLOFCM_00713 1.42e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GBCLOFCM_00714 4.01e-261 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
GBCLOFCM_00715 2.87e-247 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GBCLOFCM_00716 9.03e-57 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_00717 2.11e-226 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_00718 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GBCLOFCM_00719 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GBCLOFCM_00720 5.25e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GBCLOFCM_00721 8.1e-236 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
GBCLOFCM_00722 5.69e-44 yvfG - - S - - - YvfG protein
GBCLOFCM_00723 3.9e-303 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GBCLOFCM_00724 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GBCLOFCM_00725 3.25e-144 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
GBCLOFCM_00726 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_00727 3.86e-286 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GBCLOFCM_00728 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GBCLOFCM_00729 1.28e-192 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GBCLOFCM_00730 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
GBCLOFCM_00731 2.91e-316 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
GBCLOFCM_00732 1.19e-262 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
GBCLOFCM_00733 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
GBCLOFCM_00735 6.37e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
GBCLOFCM_00736 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GBCLOFCM_00737 7.15e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00738 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_00739 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GBCLOFCM_00740 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GBCLOFCM_00741 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GBCLOFCM_00742 4.44e-251 - - - S - - - Glycosyl hydrolase
GBCLOFCM_00743 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_00744 5.59e-198 yvbV - - EG - - - EamA-like transporter family
GBCLOFCM_00745 6.96e-206 yvbU - - K - - - Transcriptional regulator
GBCLOFCM_00746 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_00747 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
GBCLOFCM_00748 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GBCLOFCM_00749 1.63e-235 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GBCLOFCM_00750 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GBCLOFCM_00751 1.62e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GBCLOFCM_00752 5.05e-157 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GBCLOFCM_00753 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
GBCLOFCM_00754 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GBCLOFCM_00755 9.77e-106 yvbK - - K - - - acetyltransferase
GBCLOFCM_00756 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
GBCLOFCM_00757 7.97e-157 yvbI - - M - - - Membrane
GBCLOFCM_00758 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
GBCLOFCM_00759 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
GBCLOFCM_00760 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GBCLOFCM_00761 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GBCLOFCM_00762 2.07e-39 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GBCLOFCM_00763 1.49e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GBCLOFCM_00764 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GBCLOFCM_00765 9.63e-60 sdpR - - K - - - transcriptional
GBCLOFCM_00766 1.13e-130 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GBCLOFCM_00768 1.13e-222 - - - - - - - -
GBCLOFCM_00769 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
GBCLOFCM_00770 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GBCLOFCM_00771 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GBCLOFCM_00772 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GBCLOFCM_00773 6.8e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GBCLOFCM_00774 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GBCLOFCM_00775 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_00776 3.85e-72 yvaP - - K - - - transcriptional
GBCLOFCM_00777 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GBCLOFCM_00778 2.44e-88 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
GBCLOFCM_00779 4.9e-48 yvzC - - K - - - transcriptional
GBCLOFCM_00780 8.14e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
GBCLOFCM_00781 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
GBCLOFCM_00782 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
GBCLOFCM_00783 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GBCLOFCM_00784 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GBCLOFCM_00786 4.62e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00787 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
GBCLOFCM_00788 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
GBCLOFCM_00789 2.27e-94 yvaD - - S - - - Family of unknown function (DUF5360)
GBCLOFCM_00790 0.0 - - - S - - - Fusaric acid resistance protein-like
GBCLOFCM_00791 5.09e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GBCLOFCM_00792 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GBCLOFCM_00793 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
GBCLOFCM_00794 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
GBCLOFCM_00795 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GBCLOFCM_00796 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GBCLOFCM_00797 3.45e-137 bdbD - - O - - - Thioredoxin
GBCLOFCM_00798 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
GBCLOFCM_00799 3.13e-111 yvgT - - S - - - membrane
GBCLOFCM_00801 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GBCLOFCM_00802 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GBCLOFCM_00803 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GBCLOFCM_00804 1.1e-116 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
GBCLOFCM_00805 7.86e-231 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
GBCLOFCM_00806 1.11e-41 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
GBCLOFCM_00807 9.32e-112 yvgO - - - - - - -
GBCLOFCM_00808 2.63e-202 yvgN - - S - - - reductase
GBCLOFCM_00809 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
GBCLOFCM_00810 1.09e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
GBCLOFCM_00811 2.54e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
GBCLOFCM_00812 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
GBCLOFCM_00813 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
GBCLOFCM_00814 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
GBCLOFCM_00815 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GBCLOFCM_00816 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GBCLOFCM_00817 1.21e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_00818 1.95e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_00819 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GBCLOFCM_00821 8.47e-230 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
GBCLOFCM_00822 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00823 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GBCLOFCM_00824 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
GBCLOFCM_00825 2.64e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GBCLOFCM_00826 3.46e-26 - - - S - - - YvrJ protein family
GBCLOFCM_00827 1.93e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
GBCLOFCM_00828 5.07e-32 - - - - - - - -
GBCLOFCM_00829 3.12e-127 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00830 0.0 yvrG - - T - - - Histidine kinase
GBCLOFCM_00831 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
GBCLOFCM_00832 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00833 1.36e-214 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GBCLOFCM_00834 1.49e-233 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_00835 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GBCLOFCM_00836 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
GBCLOFCM_00837 9.24e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_00838 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
GBCLOFCM_00839 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GBCLOFCM_00840 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GBCLOFCM_00841 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
GBCLOFCM_00842 9.56e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00843 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_00844 1.22e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
GBCLOFCM_00845 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GBCLOFCM_00846 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GBCLOFCM_00847 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
GBCLOFCM_00848 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GBCLOFCM_00849 1.77e-203 yuxN - - K - - - Transcriptional regulator
GBCLOFCM_00850 2.86e-315 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00851 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_00852 9.21e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBCLOFCM_00853 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
GBCLOFCM_00854 1.23e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00855 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
GBCLOFCM_00856 3.48e-88 - - - S - - - YusW-like protein
GBCLOFCM_00857 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GBCLOFCM_00858 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
GBCLOFCM_00859 4.87e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GBCLOFCM_00860 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00861 1.7e-84 yusQ - - S - - - Tautomerase enzyme
GBCLOFCM_00862 0.0 yusP - - P - - - Major facilitator superfamily
GBCLOFCM_00863 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
GBCLOFCM_00864 8.66e-70 yusN - - M - - - Coat F domain
GBCLOFCM_00865 2.23e-54 - - - - - - - -
GBCLOFCM_00866 3.46e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GBCLOFCM_00867 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
GBCLOFCM_00868 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
GBCLOFCM_00869 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GBCLOFCM_00870 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GBCLOFCM_00871 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GBCLOFCM_00872 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
GBCLOFCM_00873 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
GBCLOFCM_00874 5.73e-73 yusE - - CO - - - Thioredoxin
GBCLOFCM_00875 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
GBCLOFCM_00876 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBCLOFCM_00877 2.64e-125 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
GBCLOFCM_00878 2.91e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GBCLOFCM_00879 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBCLOFCM_00880 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GBCLOFCM_00881 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
GBCLOFCM_00882 3.99e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBCLOFCM_00883 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
GBCLOFCM_00884 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
GBCLOFCM_00885 1.78e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GBCLOFCM_00886 7.18e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_00887 1.12e-54 - - - - - - - -
GBCLOFCM_00889 6.46e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
GBCLOFCM_00890 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
GBCLOFCM_00891 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GBCLOFCM_00892 5.79e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GBCLOFCM_00893 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_00894 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GBCLOFCM_00895 5.31e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
GBCLOFCM_00896 6.13e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GBCLOFCM_00897 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_00898 1.13e-218 bsn - - L - - - Ribonuclease
GBCLOFCM_00899 4.02e-302 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GBCLOFCM_00900 8.16e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GBCLOFCM_00902 3.46e-241 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GBCLOFCM_00903 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
GBCLOFCM_00904 1.17e-185 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GBCLOFCM_00905 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GBCLOFCM_00906 1.46e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GBCLOFCM_00907 1.47e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
GBCLOFCM_00908 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
GBCLOFCM_00909 1.84e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GBCLOFCM_00910 2.2e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
GBCLOFCM_00911 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
GBCLOFCM_00912 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GBCLOFCM_00913 1.52e-79 yunG - - - - - - -
GBCLOFCM_00914 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
GBCLOFCM_00915 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
GBCLOFCM_00916 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GBCLOFCM_00917 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
GBCLOFCM_00918 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
GBCLOFCM_00919 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
GBCLOFCM_00920 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GBCLOFCM_00921 1.29e-142 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GBCLOFCM_00922 3.2e-63 yutD - - S - - - protein conserved in bacteria
GBCLOFCM_00923 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
GBCLOFCM_00924 1.5e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GBCLOFCM_00925 3.34e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GBCLOFCM_00926 1.55e-253 yutH - - S - - - Spore coat protein
GBCLOFCM_00927 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GBCLOFCM_00928 1.05e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GBCLOFCM_00929 4.96e-219 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GBCLOFCM_00930 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
GBCLOFCM_00931 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
GBCLOFCM_00932 6.61e-75 yuzD - - S - - - protein conserved in bacteria
GBCLOFCM_00933 1.06e-224 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GBCLOFCM_00934 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
GBCLOFCM_00935 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GBCLOFCM_00936 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GBCLOFCM_00937 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
GBCLOFCM_00938 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_00939 1.58e-146 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
GBCLOFCM_00940 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GBCLOFCM_00942 5.51e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
GBCLOFCM_00943 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GBCLOFCM_00944 9.78e-47 yuiB - - S - - - Putative membrane protein
GBCLOFCM_00945 1.1e-149 yuiC - - S - - - protein conserved in bacteria
GBCLOFCM_00946 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
GBCLOFCM_00947 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GBCLOFCM_00948 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
GBCLOFCM_00949 6.84e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
GBCLOFCM_00950 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
GBCLOFCM_00951 7.35e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
GBCLOFCM_00952 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_00953 4.07e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GBCLOFCM_00954 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
GBCLOFCM_00955 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
GBCLOFCM_00956 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_00957 8.23e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
GBCLOFCM_00958 4.76e-88 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
GBCLOFCM_00959 2.88e-64 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
GBCLOFCM_00960 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GBCLOFCM_00961 2.18e-288 yukF - - QT - - - Transcriptional regulator
GBCLOFCM_00962 5.73e-26 yukE - - S - - - Belongs to the WXG100 family
GBCLOFCM_00963 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
GBCLOFCM_00964 2.21e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
GBCLOFCM_00965 2.92e-178 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GBCLOFCM_00966 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GBCLOFCM_00967 0.0 yueB - - S - - - type VII secretion protein EsaA
GBCLOFCM_00968 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
GBCLOFCM_00969 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_00970 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
GBCLOFCM_00971 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
GBCLOFCM_00972 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
GBCLOFCM_00973 1.11e-243 yueF - - S - - - transporter activity
GBCLOFCM_00974 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
GBCLOFCM_00975 1.63e-52 yueH - - S - - - YueH-like protein
GBCLOFCM_00976 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
GBCLOFCM_00977 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
GBCLOFCM_00978 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GBCLOFCM_00979 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
GBCLOFCM_00980 8.73e-09 yuzC - - - - - - -
GBCLOFCM_00981 6.29e-10 - - - S - - - DegQ (SacQ) family
GBCLOFCM_00982 3.3e-208 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
GBCLOFCM_00984 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_00985 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_00986 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
GBCLOFCM_00987 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
GBCLOFCM_00988 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GBCLOFCM_00989 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GBCLOFCM_00990 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GBCLOFCM_00991 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GBCLOFCM_00992 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GBCLOFCM_00993 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GBCLOFCM_00994 1.42e-21 - - - - - - - -
GBCLOFCM_00995 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
GBCLOFCM_00996 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GBCLOFCM_00997 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GBCLOFCM_00998 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_00999 4.13e-239 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
GBCLOFCM_01000 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GBCLOFCM_01001 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GBCLOFCM_01002 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
GBCLOFCM_01003 4.67e-62 yuxK - - S - - - protein conserved in bacteria
GBCLOFCM_01004 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
GBCLOFCM_01005 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
GBCLOFCM_01007 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
GBCLOFCM_01008 1.23e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
GBCLOFCM_01009 5.26e-297 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_01010 1.16e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GBCLOFCM_01011 1.53e-52 yugE - - S - - - Domain of unknown function (DUF1871)
GBCLOFCM_01012 9.89e-201 yugF - - I - - - Hydrolase
GBCLOFCM_01013 6.74e-112 alaR - - K - - - Transcriptional regulator
GBCLOFCM_01014 5.2e-253 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
GBCLOFCM_01015 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GBCLOFCM_01016 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
GBCLOFCM_01017 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
GBCLOFCM_01018 6.49e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
GBCLOFCM_01019 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GBCLOFCM_01021 4.22e-95 yugN - - S - - - YugN-like family
GBCLOFCM_01022 4.61e-230 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
GBCLOFCM_01023 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
GBCLOFCM_01024 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GBCLOFCM_01025 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GBCLOFCM_01026 4.25e-94 yugU - - S - - - Uncharacterised protein family UPF0047
GBCLOFCM_01027 1.44e-47 - - - - - - - -
GBCLOFCM_01028 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
GBCLOFCM_01029 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_01030 5.64e-296 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_01031 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_01032 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_01033 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
GBCLOFCM_01034 2.36e-171 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GBCLOFCM_01035 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GBCLOFCM_01036 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
GBCLOFCM_01037 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
GBCLOFCM_01038 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GBCLOFCM_01039 1.73e-252 yubA - - S - - - transporter activity
GBCLOFCM_01040 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GBCLOFCM_01042 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
GBCLOFCM_01043 0.0 yubD - - P - - - Major Facilitator Superfamily
GBCLOFCM_01044 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GBCLOFCM_01045 3.31e-52 yubF - - S - - - yiaA/B two helix domain
GBCLOFCM_01046 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
GBCLOFCM_01047 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GBCLOFCM_01048 8.28e-118 yuaB - - - - - - -
GBCLOFCM_01049 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
GBCLOFCM_01050 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GBCLOFCM_01051 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
GBCLOFCM_01052 3.5e-138 yuaD - - - - - - -
GBCLOFCM_01053 1.95e-109 yuaE - - S - - - DinB superfamily
GBCLOFCM_01054 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
GBCLOFCM_01055 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
GBCLOFCM_01056 1.2e-122 - - - M - - - FR47-like protein
GBCLOFCM_01057 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
GBCLOFCM_01058 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_01059 3.02e-57 - - - - - - - -
GBCLOFCM_01081 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GBCLOFCM_01082 6.97e-264 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBCLOFCM_01083 6.43e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
GBCLOFCM_01084 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
GBCLOFCM_01085 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GBCLOFCM_01086 1.3e-53 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
GBCLOFCM_01087 1.83e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
GBCLOFCM_01088 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
GBCLOFCM_01089 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
GBCLOFCM_01091 3.4e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
GBCLOFCM_01092 2.59e-229 ytcB - - M - - - NAD-dependent epimerase dehydratase
GBCLOFCM_01093 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GBCLOFCM_01094 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
GBCLOFCM_01095 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
GBCLOFCM_01096 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GBCLOFCM_01097 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GBCLOFCM_01098 1.34e-194 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GBCLOFCM_01099 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GBCLOFCM_01100 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GBCLOFCM_01101 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GBCLOFCM_01102 2.65e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GBCLOFCM_01103 6.86e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GBCLOFCM_01104 3.03e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GBCLOFCM_01105 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GBCLOFCM_01106 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
GBCLOFCM_01107 2.83e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GBCLOFCM_01108 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GBCLOFCM_01109 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GBCLOFCM_01110 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GBCLOFCM_01111 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GBCLOFCM_01112 6.79e-95 ytkA - - S - - - YtkA-like
GBCLOFCM_01114 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GBCLOFCM_01115 1.59e-81 ytkC - - S - - - Bacteriophage holin family
GBCLOFCM_01116 4.24e-95 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GBCLOFCM_01117 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GBCLOFCM_01118 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GBCLOFCM_01119 3.92e-127 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GBCLOFCM_01120 5.24e-92 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GBCLOFCM_01121 1.06e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GBCLOFCM_01122 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
GBCLOFCM_01123 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GBCLOFCM_01124 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBCLOFCM_01125 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GBCLOFCM_01126 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_01127 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GBCLOFCM_01128 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
GBCLOFCM_01129 1.61e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
GBCLOFCM_01130 1.59e-135 ytqB - - J - - - Putative rRNA methylase
GBCLOFCM_01131 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
GBCLOFCM_01132 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
GBCLOFCM_01134 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
GBCLOFCM_01135 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_01136 6.58e-197 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GBCLOFCM_01137 5.28e-179 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
GBCLOFCM_01138 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_01139 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GBCLOFCM_01140 5.25e-112 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_01141 6.44e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
GBCLOFCM_01142 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_01143 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
GBCLOFCM_01144 2.67e-76 yttA - - S - - - Pfam Transposase IS66
GBCLOFCM_01145 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
GBCLOFCM_01146 1.1e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GBCLOFCM_01147 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
GBCLOFCM_01148 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GBCLOFCM_01149 1.22e-68 ytwF - - P - - - Sulfurtransferase
GBCLOFCM_01150 2.1e-260 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GBCLOFCM_01151 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GBCLOFCM_01152 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GBCLOFCM_01153 6.33e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GBCLOFCM_01154 3.75e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_01155 3.24e-219 - - - S - - - Acetyl xylan esterase (AXE1)
GBCLOFCM_01156 9.13e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GBCLOFCM_01157 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GBCLOFCM_01158 1.82e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GBCLOFCM_01159 1.62e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GBCLOFCM_01160 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GBCLOFCM_01161 2.95e-284 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GBCLOFCM_01162 1.28e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
GBCLOFCM_01163 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GBCLOFCM_01164 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GBCLOFCM_01165 0.0 ytdP - - K - - - Transcriptional regulator
GBCLOFCM_01166 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GBCLOFCM_01167 3.79e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
GBCLOFCM_01168 5.81e-95 yteS - - G - - - transport
GBCLOFCM_01169 1.07e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
GBCLOFCM_01170 2.3e-151 yteU - - S - - - Integral membrane protein
GBCLOFCM_01171 2.14e-36 yteV - - S - - - Sporulation protein Cse60
GBCLOFCM_01172 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
GBCLOFCM_01173 1.41e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
GBCLOFCM_01174 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_01175 1.12e-40 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GBCLOFCM_01176 1.51e-114 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GBCLOFCM_01177 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
GBCLOFCM_01178 3.27e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GBCLOFCM_01179 6.35e-258 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
GBCLOFCM_01180 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
GBCLOFCM_01181 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
GBCLOFCM_01182 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GBCLOFCM_01183 1.75e-129 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GBCLOFCM_01184 4.92e-212 ytlQ - - - - - - -
GBCLOFCM_01185 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GBCLOFCM_01186 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GBCLOFCM_01187 3.02e-192 ytmP - - M - - - Phosphotransferase
GBCLOFCM_01188 9.51e-61 ytzH - - S - - - YtzH-like protein
GBCLOFCM_01189 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GBCLOFCM_01190 3.07e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GBCLOFCM_01191 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GBCLOFCM_01192 1.17e-67 ytzB - - S - - - small secreted protein
GBCLOFCM_01193 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
GBCLOFCM_01194 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
GBCLOFCM_01195 9.1e-75 ytpP - - CO - - - Thioredoxin
GBCLOFCM_01196 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
GBCLOFCM_01197 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBCLOFCM_01198 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GBCLOFCM_01199 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GBCLOFCM_01200 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GBCLOFCM_01201 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
GBCLOFCM_01202 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
GBCLOFCM_01203 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GBCLOFCM_01204 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GBCLOFCM_01205 3.96e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GBCLOFCM_01206 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GBCLOFCM_01207 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
GBCLOFCM_01208 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
GBCLOFCM_01209 6.12e-139 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GBCLOFCM_01210 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GBCLOFCM_01211 4.36e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBCLOFCM_01213 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GBCLOFCM_01214 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
GBCLOFCM_01215 1.71e-64 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GBCLOFCM_01216 2.94e-142 yttP - - K - - - Transcriptional regulator
GBCLOFCM_01217 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GBCLOFCM_01218 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GBCLOFCM_01219 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GBCLOFCM_01220 5.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GBCLOFCM_01221 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GBCLOFCM_01222 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GBCLOFCM_01223 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GBCLOFCM_01224 0.0 ytcJ - - S - - - amidohydrolase
GBCLOFCM_01225 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBCLOFCM_01226 2.05e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
GBCLOFCM_01227 2.36e-111 yteJ - - S - - - RDD family
GBCLOFCM_01228 5.87e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
GBCLOFCM_01229 3.05e-94 ytfJ - - S - - - Sporulation protein YtfJ
GBCLOFCM_01230 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GBCLOFCM_01231 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GBCLOFCM_01232 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GBCLOFCM_01233 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GBCLOFCM_01234 4.3e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GBCLOFCM_01235 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GBCLOFCM_01237 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_01238 4.53e-166 ytkL - - S - - - Belongs to the UPF0173 family
GBCLOFCM_01239 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
GBCLOFCM_01240 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GBCLOFCM_01241 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GBCLOFCM_01242 1.29e-190 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GBCLOFCM_01243 9.59e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_01244 3.21e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_01245 2.21e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GBCLOFCM_01246 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_01247 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
GBCLOFCM_01248 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_01249 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
GBCLOFCM_01250 1.58e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GBCLOFCM_01251 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
GBCLOFCM_01252 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
GBCLOFCM_01253 2.15e-63 ytpI - - S - - - YtpI-like protein
GBCLOFCM_01254 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
GBCLOFCM_01255 1.15e-39 - - - - - - - -
GBCLOFCM_01256 5.98e-111 ytrI - - - - - - -
GBCLOFCM_01257 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
GBCLOFCM_01258 2.2e-34 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GBCLOFCM_01259 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GBCLOFCM_01260 3.09e-254 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GBCLOFCM_01261 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GBCLOFCM_01262 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GBCLOFCM_01263 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GBCLOFCM_01264 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GBCLOFCM_01265 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GBCLOFCM_01266 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
GBCLOFCM_01267 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
GBCLOFCM_01268 1.56e-93 ytwI - - S - - - membrane
GBCLOFCM_01269 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GBCLOFCM_01270 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
GBCLOFCM_01271 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
GBCLOFCM_01272 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_01273 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
GBCLOFCM_01274 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBCLOFCM_01275 5.13e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GBCLOFCM_01276 3.77e-97 ytaF - - P - - - Probably functions as a manganese efflux pump
GBCLOFCM_01277 2.24e-24 ytaF - - P - - - Probably functions as a manganese efflux pump
GBCLOFCM_01278 7.74e-124 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GBCLOFCM_01279 4.54e-205 ytbE - - S - - - reductase
GBCLOFCM_01280 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
GBCLOFCM_01281 9.85e-88 ytcD - - K - - - Transcriptional regulator
GBCLOFCM_01282 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GBCLOFCM_01283 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GBCLOFCM_01284 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GBCLOFCM_01285 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
GBCLOFCM_01286 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GBCLOFCM_01287 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
GBCLOFCM_01288 5.98e-206 ytxC - - S - - - YtxC-like family
GBCLOFCM_01289 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBCLOFCM_01290 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
GBCLOFCM_01291 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_01292 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
GBCLOFCM_01293 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GBCLOFCM_01294 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GBCLOFCM_01297 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GBCLOFCM_01298 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GBCLOFCM_01299 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GBCLOFCM_01300 1.27e-59 ysdA - - S - - - Membrane
GBCLOFCM_01301 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
GBCLOFCM_01302 2.93e-260 ysdC - - G - - - COG1363 Cellulase M and related proteins
GBCLOFCM_01303 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GBCLOFCM_01304 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GBCLOFCM_01305 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
GBCLOFCM_01306 1.99e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GBCLOFCM_01307 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
GBCLOFCM_01308 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GBCLOFCM_01309 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GBCLOFCM_01310 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GBCLOFCM_01311 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
GBCLOFCM_01312 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
GBCLOFCM_01313 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
GBCLOFCM_01314 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
GBCLOFCM_01315 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
GBCLOFCM_01316 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
GBCLOFCM_01317 2.51e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
GBCLOFCM_01318 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
GBCLOFCM_01319 1.05e-169 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBCLOFCM_01320 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GBCLOFCM_01321 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBCLOFCM_01322 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBCLOFCM_01323 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GBCLOFCM_01324 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
GBCLOFCM_01325 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
GBCLOFCM_01326 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GBCLOFCM_01327 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
GBCLOFCM_01328 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GBCLOFCM_01329 3.46e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_01330 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
GBCLOFCM_01331 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
GBCLOFCM_01332 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
GBCLOFCM_01334 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
GBCLOFCM_01335 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GBCLOFCM_01336 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GBCLOFCM_01337 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GBCLOFCM_01338 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
GBCLOFCM_01339 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
GBCLOFCM_01340 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GBCLOFCM_01341 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GBCLOFCM_01342 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
GBCLOFCM_01343 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_01344 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_01345 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GBCLOFCM_01346 1.62e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
GBCLOFCM_01347 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GBCLOFCM_01348 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GBCLOFCM_01349 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GBCLOFCM_01351 5.58e-182 ysnF - - S - - - protein conserved in bacteria
GBCLOFCM_01352 2.16e-103 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
GBCLOFCM_01354 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GBCLOFCM_01355 6.57e-102 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GBCLOFCM_01356 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GBCLOFCM_01357 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBCLOFCM_01358 7.43e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GBCLOFCM_01359 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBCLOFCM_01360 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBCLOFCM_01361 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
GBCLOFCM_01362 7.28e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GBCLOFCM_01363 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GBCLOFCM_01364 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
GBCLOFCM_01365 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GBCLOFCM_01366 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GBCLOFCM_01367 3.35e-116 ysxD - - - - - - -
GBCLOFCM_01368 2.74e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GBCLOFCM_01369 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
GBCLOFCM_01370 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GBCLOFCM_01371 2.91e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GBCLOFCM_01372 1.51e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
GBCLOFCM_01373 2.04e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GBCLOFCM_01374 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
GBCLOFCM_01375 3.26e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GBCLOFCM_01376 1.53e-35 - - - - - - - -
GBCLOFCM_01377 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GBCLOFCM_01378 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GBCLOFCM_01379 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GBCLOFCM_01380 7.4e-212 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
GBCLOFCM_01381 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
GBCLOFCM_01382 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GBCLOFCM_01383 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
GBCLOFCM_01384 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GBCLOFCM_01385 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
GBCLOFCM_01386 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GBCLOFCM_01387 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
GBCLOFCM_01388 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GBCLOFCM_01389 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
GBCLOFCM_01390 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GBCLOFCM_01391 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
GBCLOFCM_01392 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GBCLOFCM_01393 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
GBCLOFCM_01394 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GBCLOFCM_01395 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
GBCLOFCM_01396 2.89e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
GBCLOFCM_01397 3.65e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
GBCLOFCM_01398 6.49e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GBCLOFCM_01399 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
GBCLOFCM_01400 4.34e-203 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
GBCLOFCM_01401 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GBCLOFCM_01402 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
GBCLOFCM_01403 1.82e-73 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GBCLOFCM_01404 2.37e-162 yebC - - K - - - transcriptional regulatory protein
GBCLOFCM_01405 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
GBCLOFCM_01407 1.47e-66 - - - S - - - Family of unknown function (DUF5412)
GBCLOFCM_01409 3.17e-150 yrzF - - T - - - serine threonine protein kinase
GBCLOFCM_01410 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
GBCLOFCM_01411 0.0 csbX - - EGP - - - the major facilitator superfamily
GBCLOFCM_01412 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
GBCLOFCM_01413 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GBCLOFCM_01414 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GBCLOFCM_01415 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
GBCLOFCM_01416 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GBCLOFCM_01417 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GBCLOFCM_01418 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
GBCLOFCM_01419 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
GBCLOFCM_01420 1.23e-144 yrbG - - S - - - membrane
GBCLOFCM_01421 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_01422 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
GBCLOFCM_01423 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GBCLOFCM_01424 3.77e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GBCLOFCM_01425 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
GBCLOFCM_01426 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GBCLOFCM_01427 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBCLOFCM_01428 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBCLOFCM_01429 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GBCLOFCM_01430 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
GBCLOFCM_01432 5.19e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GBCLOFCM_01433 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GBCLOFCM_01434 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GBCLOFCM_01435 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GBCLOFCM_01436 4.76e-55 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_01437 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GBCLOFCM_01438 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GBCLOFCM_01439 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
GBCLOFCM_01440 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GBCLOFCM_01441 1.23e-108 yrrD - - S - - - protein conserved in bacteria
GBCLOFCM_01442 8.4e-42 yrzR - - - - - - -
GBCLOFCM_01443 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
GBCLOFCM_01444 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GBCLOFCM_01445 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GBCLOFCM_01446 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GBCLOFCM_01447 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GBCLOFCM_01448 3.07e-242 yrrI - - S - - - AI-2E family transporter
GBCLOFCM_01449 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GBCLOFCM_01450 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
GBCLOFCM_01451 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBCLOFCM_01452 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
GBCLOFCM_01453 1.24e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBCLOFCM_01454 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
GBCLOFCM_01455 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GBCLOFCM_01456 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
GBCLOFCM_01457 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GBCLOFCM_01458 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GBCLOFCM_01459 4.56e-63 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
GBCLOFCM_01460 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
GBCLOFCM_01461 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
GBCLOFCM_01462 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
GBCLOFCM_01463 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
GBCLOFCM_01464 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GBCLOFCM_01465 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
GBCLOFCM_01466 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GBCLOFCM_01467 6.93e-49 yrhC - - S - - - YrhC-like protein
GBCLOFCM_01468 4.97e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
GBCLOFCM_01469 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GBCLOFCM_01470 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
GBCLOFCM_01472 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
GBCLOFCM_01474 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
GBCLOFCM_01475 1.5e-124 yrhH - - Q - - - methyltransferase
GBCLOFCM_01476 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
GBCLOFCM_01477 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GBCLOFCM_01478 5.19e-60 yrhK - - S - - - YrhK-like protein
GBCLOFCM_01479 0.0 oatA - - I - - - Acyltransferase family
GBCLOFCM_01480 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
GBCLOFCM_01481 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_01482 8.04e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
GBCLOFCM_01483 5.63e-137 yrhP - - E - - - LysE type translocator
GBCLOFCM_01484 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_01485 0.0 levR - - K - - - PTS system fructose IIA component
GBCLOFCM_01486 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GBCLOFCM_01487 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
GBCLOFCM_01488 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
GBCLOFCM_01489 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
GBCLOFCM_01490 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GBCLOFCM_01491 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GBCLOFCM_01492 7.98e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
GBCLOFCM_01493 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
GBCLOFCM_01494 1.23e-65 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
GBCLOFCM_01495 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
GBCLOFCM_01496 6.11e-36 yraE - - - ko:K06440 - ko00000 -
GBCLOFCM_01497 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GBCLOFCM_01498 9.61e-84 yraF - - M - - - Spore coat protein
GBCLOFCM_01499 1.2e-49 yraG - - - ko:K06440 - ko00000 -
GBCLOFCM_01500 5.45e-86 - - - E - - - Glyoxalase-like domain
GBCLOFCM_01502 2.92e-81 - - - T - - - sh3 domain protein
GBCLOFCM_01503 2.69e-79 - - - T - - - sh3 domain protein
GBCLOFCM_01504 1.45e-192 - - - S - - - Alpha beta hydrolase
GBCLOFCM_01505 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_01506 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GBCLOFCM_01508 1.45e-258 yraM - - S - - - PrpF protein
GBCLOFCM_01509 2.97e-210 yraN - - K - - - Transcriptional regulator
GBCLOFCM_01510 5.31e-286 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GBCLOFCM_01511 1.15e-237 yrpG - - C - - - Aldo/keto reductase family
GBCLOFCM_01512 6.39e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_01513 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
GBCLOFCM_01515 1.14e-160 yrpD - - S - - - Domain of unknown function, YrpD
GBCLOFCM_01516 1.19e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GBCLOFCM_01517 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GBCLOFCM_01518 2.45e-211 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
GBCLOFCM_01519 1.42e-118 yrdA - - S - - - DinB family
GBCLOFCM_01520 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
GBCLOFCM_01521 4.27e-132 yrdC - - Q - - - Isochorismatase family
GBCLOFCM_01522 2.38e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GBCLOFCM_01523 4.64e-44 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
GBCLOFCM_01524 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
GBCLOFCM_01525 9.34e-176 azlC - - E - - - AzlC protein
GBCLOFCM_01526 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
GBCLOFCM_01527 3.01e-293 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GBCLOFCM_01528 4.97e-150 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GBCLOFCM_01529 1.01e-86 yodA - - S - - - tautomerase
GBCLOFCM_01530 9.21e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
GBCLOFCM_01531 5.84e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
GBCLOFCM_01532 9.87e-204 - - - K - - - Transcriptional regulator
GBCLOFCM_01533 1.51e-41 yrdR - - EG - - - EamA-like transporter family
GBCLOFCM_01534 4.77e-10 yrdR - - EG - - - EamA-like transporter family
GBCLOFCM_01535 4.83e-116 yrdR - - EG - - - EamA-like transporter family
GBCLOFCM_01536 2.45e-23 - - - S - - - YrzO-like protein
GBCLOFCM_01537 7.2e-298 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GBCLOFCM_01538 5.95e-106 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
GBCLOFCM_01539 3.76e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_01540 5.9e-193 bltR - - K - - - helix_turn_helix, mercury resistance
GBCLOFCM_01541 2.21e-138 yrkC - - G - - - Cupin domain
GBCLOFCM_01542 4.38e-52 yrkD - - S - - - protein conserved in bacteria
GBCLOFCM_01543 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
GBCLOFCM_01544 2.28e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
GBCLOFCM_01545 7.96e-273 yrkH - - P - - - Rhodanese Homology Domain
GBCLOFCM_01546 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
GBCLOFCM_01547 1.9e-149 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
GBCLOFCM_01548 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
GBCLOFCM_01549 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
GBCLOFCM_01550 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
GBCLOFCM_01551 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GBCLOFCM_01552 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
GBCLOFCM_01553 7.32e-306 yrkQ - - T - - - Histidine kinase
GBCLOFCM_01554 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_01555 7.83e-123 xkdA - - E - - - IrrE N-terminal-like domain
GBCLOFCM_01557 7.18e-131 yqaC - - F - - - adenylate kinase activity
GBCLOFCM_01558 2.62e-117 - - - K - - - Transcriptional regulator PadR-like family
GBCLOFCM_01559 9.17e-205 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
GBCLOFCM_01560 3.56e-08 - - - S - - - Bacillus cereus group antimicrobial protein
GBCLOFCM_01561 3.63e-53 yqaQ - - L - - - Transposase
GBCLOFCM_01562 7.29e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
GBCLOFCM_01564 6.56e-104 yqaS - - L - - - DNA packaging
GBCLOFCM_01565 1.76e-33 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
GBCLOFCM_01566 1.42e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GBCLOFCM_01567 4.2e-68 - 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
GBCLOFCM_01568 2.54e-18 - - - K - - - Bacterial regulatory proteins, tetR family
GBCLOFCM_01569 2.02e-161 - - - EGP - - - Necrosis inducing protein (NPP1)
GBCLOFCM_01570 6.92e-106 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
GBCLOFCM_01571 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GBCLOFCM_01572 1.45e-78 - - - S - - - TraX protein
GBCLOFCM_01574 3.56e-259 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
GBCLOFCM_01577 1.83e-99 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GBCLOFCM_01578 2.09e-111 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GBCLOFCM_01579 0.0 - - - L ko:K06400 - ko00000 Recombinase
GBCLOFCM_01580 4.6e-285 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
GBCLOFCM_01581 1.68e-80 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_01582 4.36e-73 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_01583 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
GBCLOFCM_01584 9.38e-171 - - - - - - - -
GBCLOFCM_01585 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
GBCLOFCM_01586 3.27e-135 yqeD - - S - - - SNARE associated Golgi protein
GBCLOFCM_01587 5.41e-173 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GBCLOFCM_01588 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
GBCLOFCM_01590 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
GBCLOFCM_01591 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GBCLOFCM_01592 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GBCLOFCM_01593 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
GBCLOFCM_01594 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GBCLOFCM_01595 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
GBCLOFCM_01596 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GBCLOFCM_01597 9.8e-179 yqeM - - Q - - - Methyltransferase
GBCLOFCM_01598 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBCLOFCM_01599 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
GBCLOFCM_01600 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GBCLOFCM_01601 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GBCLOFCM_01602 2.36e-22 - - - S - - - YqzM-like protein
GBCLOFCM_01603 4.74e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GBCLOFCM_01604 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GBCLOFCM_01605 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GBCLOFCM_01606 8.64e-196 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
GBCLOFCM_01607 9.18e-74 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
GBCLOFCM_01608 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
GBCLOFCM_01609 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GBCLOFCM_01610 1.23e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GBCLOFCM_01611 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GBCLOFCM_01612 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GBCLOFCM_01613 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GBCLOFCM_01614 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GBCLOFCM_01615 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
GBCLOFCM_01616 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GBCLOFCM_01617 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
GBCLOFCM_01618 4.9e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
GBCLOFCM_01619 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GBCLOFCM_01620 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
GBCLOFCM_01621 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
GBCLOFCM_01622 4.35e-192 yqfA - - S - - - UPF0365 protein
GBCLOFCM_01623 3.5e-53 yqfB - - - - - - -
GBCLOFCM_01624 2.07e-60 yqfC - - S - - - sporulation protein YqfC
GBCLOFCM_01625 9.93e-241 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
GBCLOFCM_01626 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
GBCLOFCM_01628 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
GBCLOFCM_01629 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBCLOFCM_01630 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GBCLOFCM_01631 1.09e-74 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GBCLOFCM_01632 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GBCLOFCM_01633 5.29e-27 - - - S - - - YqzL-like protein
GBCLOFCM_01634 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GBCLOFCM_01635 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GBCLOFCM_01636 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GBCLOFCM_01637 3.29e-144 ccpN - - K - - - CBS domain
GBCLOFCM_01638 1.29e-190 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GBCLOFCM_01639 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
GBCLOFCM_01640 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GBCLOFCM_01641 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GBCLOFCM_01642 6.28e-74 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GBCLOFCM_01643 4.66e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GBCLOFCM_01644 3.77e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBCLOFCM_01645 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GBCLOFCM_01646 1.33e-44 yqfQ - - S - - - YqfQ-like protein
GBCLOFCM_01647 4.45e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GBCLOFCM_01648 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GBCLOFCM_01649 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
GBCLOFCM_01650 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GBCLOFCM_01651 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
GBCLOFCM_01652 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
GBCLOFCM_01653 2.04e-81 yqfX - - S - - - membrane
GBCLOFCM_01654 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GBCLOFCM_01655 3.15e-54 yqfZ - - M ko:K06417 - ko00000 LysM domain
GBCLOFCM_01656 2.05e-99 yqgA - - - - - - -
GBCLOFCM_01657 3.41e-117 yqgB - - S - - - Protein of unknown function (DUF1189)
GBCLOFCM_01658 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
GBCLOFCM_01659 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
GBCLOFCM_01660 3.88e-287 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
GBCLOFCM_01661 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
GBCLOFCM_01662 2.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GBCLOFCM_01663 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GBCLOFCM_01664 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
GBCLOFCM_01665 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBCLOFCM_01666 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBCLOFCM_01667 9e-93 yqzC - - S - - - YceG-like family
GBCLOFCM_01668 3.42e-68 yqzD - - - - - - -
GBCLOFCM_01670 1.98e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
GBCLOFCM_01671 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GBCLOFCM_01672 1.88e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBCLOFCM_01673 3.38e-14 yqgO - - - - - - -
GBCLOFCM_01674 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
GBCLOFCM_01675 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
GBCLOFCM_01676 4.65e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GBCLOFCM_01677 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GBCLOFCM_01678 5.47e-284 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
GBCLOFCM_01679 2.69e-256 yqgU - - - - - - -
GBCLOFCM_01680 2.88e-40 yqgV - - S - - - Thiamine-binding protein
GBCLOFCM_01681 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
GBCLOFCM_01682 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
GBCLOFCM_01683 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
GBCLOFCM_01684 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
GBCLOFCM_01686 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GBCLOFCM_01687 2.35e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GBCLOFCM_01688 1.51e-233 yqxL - - P - - - Mg2 transporter protein
GBCLOFCM_01689 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
GBCLOFCM_01690 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GBCLOFCM_01691 1.51e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
GBCLOFCM_01692 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
GBCLOFCM_01693 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
GBCLOFCM_01694 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
GBCLOFCM_01695 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GBCLOFCM_01696 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
GBCLOFCM_01697 8.36e-30 yqzE - - S - - - YqzE-like protein
GBCLOFCM_01698 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
GBCLOFCM_01699 1.76e-159 yqxM - - - ko:K19433 - ko00000 -
GBCLOFCM_01700 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
GBCLOFCM_01701 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
GBCLOFCM_01702 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
GBCLOFCM_01703 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
GBCLOFCM_01704 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
GBCLOFCM_01705 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GBCLOFCM_01706 1.64e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
GBCLOFCM_01707 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GBCLOFCM_01708 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GBCLOFCM_01709 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
GBCLOFCM_01710 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GBCLOFCM_01711 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GBCLOFCM_01712 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GBCLOFCM_01713 5.18e-81 yqhP - - - - - - -
GBCLOFCM_01714 1.21e-219 yqhQ - - S - - - Protein of unknown function (DUF1385)
GBCLOFCM_01715 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
GBCLOFCM_01716 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
GBCLOFCM_01717 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GBCLOFCM_01718 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBCLOFCM_01719 9.8e-27 yqhV - - S - - - Protein of unknown function (DUF2619)
GBCLOFCM_01720 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
GBCLOFCM_01721 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
GBCLOFCM_01722 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
GBCLOFCM_01723 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
GBCLOFCM_01724 1.82e-245 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
GBCLOFCM_01725 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
GBCLOFCM_01726 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
GBCLOFCM_01727 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
GBCLOFCM_01728 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GBCLOFCM_01729 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GBCLOFCM_01730 1.65e-88 yqhY - - S - - - protein conserved in bacteria
GBCLOFCM_01731 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBCLOFCM_01732 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBCLOFCM_01733 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBCLOFCM_01734 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBCLOFCM_01735 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GBCLOFCM_01736 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GBCLOFCM_01737 9.88e-170 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
GBCLOFCM_01738 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GBCLOFCM_01739 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GBCLOFCM_01740 1.47e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
GBCLOFCM_01741 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GBCLOFCM_01743 1.54e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GBCLOFCM_01744 4.74e-37 - - - - - - - -
GBCLOFCM_01745 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
GBCLOFCM_01746 4.29e-171 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GBCLOFCM_01747 1.34e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GBCLOFCM_01748 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
GBCLOFCM_01749 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
GBCLOFCM_01750 4.75e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GBCLOFCM_01751 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
GBCLOFCM_01752 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GBCLOFCM_01753 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
GBCLOFCM_01754 0.0 bkdR - - KT - - - Transcriptional regulator
GBCLOFCM_01755 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
GBCLOFCM_01756 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GBCLOFCM_01757 1.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
GBCLOFCM_01758 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GBCLOFCM_01759 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GBCLOFCM_01760 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GBCLOFCM_01761 1.95e-290 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GBCLOFCM_01762 7.45e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
GBCLOFCM_01763 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_01764 1.21e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GBCLOFCM_01765 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
GBCLOFCM_01766 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GBCLOFCM_01767 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GBCLOFCM_01768 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GBCLOFCM_01769 1.88e-225 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
GBCLOFCM_01770 2.41e-128 yqjB - - S - - - protein conserved in bacteria
GBCLOFCM_01772 4.67e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
GBCLOFCM_01773 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GBCLOFCM_01774 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
GBCLOFCM_01775 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
GBCLOFCM_01776 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBCLOFCM_01777 1.77e-32 yqzJ - - - - - - -
GBCLOFCM_01778 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBCLOFCM_01779 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GBCLOFCM_01780 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GBCLOFCM_01781 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GBCLOFCM_01782 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GBCLOFCM_01783 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBCLOFCM_01784 1.72e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GBCLOFCM_01785 0.0 rocB - - E - - - arginine degradation protein
GBCLOFCM_01786 1.88e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBCLOFCM_01787 3.27e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GBCLOFCM_01788 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_01789 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
GBCLOFCM_01790 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GBCLOFCM_01791 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_01793 3.63e-288 yqjV - - G - - - Major Facilitator Superfamily
GBCLOFCM_01795 4.9e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBCLOFCM_01796 5.37e-65 yqiX - - S - - - YolD-like protein
GBCLOFCM_01797 3.16e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
GBCLOFCM_01798 6.44e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
GBCLOFCM_01799 9.27e-248 yqkA - - K - - - GrpB protein
GBCLOFCM_01800 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
GBCLOFCM_01801 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
GBCLOFCM_01802 2.25e-209 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GBCLOFCM_01803 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
GBCLOFCM_01804 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
GBCLOFCM_01805 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
GBCLOFCM_01806 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
GBCLOFCM_01807 3.29e-63 yqxK - - L - - - DNA helicase
GBCLOFCM_01808 3.54e-206 yqxK - - L - - - DNA helicase
GBCLOFCM_01809 3.18e-77 ansR - - K - - - Transcriptional regulator
GBCLOFCM_01810 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
GBCLOFCM_01811 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
GBCLOFCM_01812 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GBCLOFCM_01813 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GBCLOFCM_01814 1.72e-40 yqkK - - - - - - -
GBCLOFCM_01815 1.77e-133 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GBCLOFCM_01816 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GBCLOFCM_01817 3.6e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
GBCLOFCM_01818 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GBCLOFCM_01819 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GBCLOFCM_01820 8.66e-264 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GBCLOFCM_01821 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
GBCLOFCM_01822 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GBCLOFCM_01823 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_01824 8.68e-119 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
GBCLOFCM_01825 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
GBCLOFCM_01826 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
GBCLOFCM_01827 1.42e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
GBCLOFCM_01828 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
GBCLOFCM_01829 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
GBCLOFCM_01830 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
GBCLOFCM_01831 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GBCLOFCM_01832 2.67e-193 ypuA - - S - - - Secreted protein
GBCLOFCM_01833 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBCLOFCM_01835 1.04e-08 - - - S - - - SNARE associated Golgi protein
GBCLOFCM_01836 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
GBCLOFCM_01837 4.99e-127 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GBCLOFCM_01838 2.96e-72 ypuD - - - - - - -
GBCLOFCM_01839 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GBCLOFCM_01840 2.05e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GBCLOFCM_01841 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBCLOFCM_01842 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GBCLOFCM_01843 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_01844 3.43e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
GBCLOFCM_01845 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GBCLOFCM_01846 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GBCLOFCM_01847 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
GBCLOFCM_01848 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GBCLOFCM_01849 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
GBCLOFCM_01850 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
GBCLOFCM_01851 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GBCLOFCM_01852 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GBCLOFCM_01853 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
GBCLOFCM_01854 5.93e-39 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GBCLOFCM_01855 3.13e-212 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GBCLOFCM_01856 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_01857 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_01858 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_01859 1.49e-254 rsiX - - - - - - -
GBCLOFCM_01860 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GBCLOFCM_01861 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBCLOFCM_01862 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GBCLOFCM_01863 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
GBCLOFCM_01864 6.62e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
GBCLOFCM_01865 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GBCLOFCM_01866 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
GBCLOFCM_01867 8.27e-143 ypbE - - M - - - Lysin motif
GBCLOFCM_01868 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
GBCLOFCM_01869 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GBCLOFCM_01870 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GBCLOFCM_01871 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GBCLOFCM_01872 2.2e-225 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
GBCLOFCM_01873 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
GBCLOFCM_01874 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
GBCLOFCM_01875 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
GBCLOFCM_01876 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
GBCLOFCM_01877 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
GBCLOFCM_01878 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GBCLOFCM_01879 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GBCLOFCM_01880 9.39e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GBCLOFCM_01881 1.13e-11 - - - S - - - YpzI-like protein
GBCLOFCM_01882 2.73e-134 yphA - - - - - - -
GBCLOFCM_01883 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
GBCLOFCM_01884 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GBCLOFCM_01885 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GBCLOFCM_01886 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
GBCLOFCM_01887 8.71e-176 yphF - - - - - - -
GBCLOFCM_01888 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GBCLOFCM_01889 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GBCLOFCM_01890 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
GBCLOFCM_01891 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GBCLOFCM_01892 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GBCLOFCM_01893 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GBCLOFCM_01894 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GBCLOFCM_01895 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GBCLOFCM_01896 5.24e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
GBCLOFCM_01897 3.6e-233 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GBCLOFCM_01898 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GBCLOFCM_01899 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GBCLOFCM_01900 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBCLOFCM_01901 8.28e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GBCLOFCM_01902 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GBCLOFCM_01903 3.7e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
GBCLOFCM_01904 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GBCLOFCM_01905 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GBCLOFCM_01906 4.31e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBCLOFCM_01907 6.97e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GBCLOFCM_01908 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GBCLOFCM_01909 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
GBCLOFCM_01910 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
GBCLOFCM_01911 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
GBCLOFCM_01912 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
GBCLOFCM_01913 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
GBCLOFCM_01914 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
GBCLOFCM_01915 2.82e-126 ypjA - - S - - - membrane
GBCLOFCM_01916 2.79e-182 ypjB - - S - - - sporulation protein
GBCLOFCM_01917 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GBCLOFCM_01918 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
GBCLOFCM_01919 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GBCLOFCM_01920 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
GBCLOFCM_01921 5.03e-152 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
GBCLOFCM_01922 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
GBCLOFCM_01923 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GBCLOFCM_01924 4e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GBCLOFCM_01925 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GBCLOFCM_01926 1.5e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GBCLOFCM_01927 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GBCLOFCM_01928 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GBCLOFCM_01929 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
GBCLOFCM_01930 2.27e-103 ypmB - - S - - - protein conserved in bacteria
GBCLOFCM_01931 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GBCLOFCM_01932 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
GBCLOFCM_01933 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
GBCLOFCM_01934 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GBCLOFCM_01935 1.43e-121 ypoC - - - - - - -
GBCLOFCM_01936 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GBCLOFCM_01937 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GBCLOFCM_01938 5.3e-240 yppC - - S - - - Protein of unknown function (DUF2515)
GBCLOFCM_01941 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
GBCLOFCM_01942 9.21e-11 - - - S - - - YppF-like protein
GBCLOFCM_01943 8.72e-68 yppG - - S - - - YppG-like protein
GBCLOFCM_01944 2.06e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GBCLOFCM_01945 6.36e-111 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
GBCLOFCM_01946 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GBCLOFCM_01947 1.63e-297 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
GBCLOFCM_01948 1.28e-125 ypsA - - S - - - Belongs to the UPF0398 family
GBCLOFCM_01949 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GBCLOFCM_01950 4.8e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GBCLOFCM_01951 9.72e-66 yqgA - - - - - - -
GBCLOFCM_01953 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
GBCLOFCM_01954 5.63e-177 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_01955 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GBCLOFCM_01956 2.14e-235 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
GBCLOFCM_01957 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
GBCLOFCM_01958 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
GBCLOFCM_01959 8.24e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
GBCLOFCM_01960 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GBCLOFCM_01961 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GBCLOFCM_01962 5.08e-22 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GBCLOFCM_01963 9.18e-140 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GBCLOFCM_01964 6.77e-52 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GBCLOFCM_01965 7.54e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
GBCLOFCM_01966 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
GBCLOFCM_01967 0.0 ypbR - - S - - - Dynamin family
GBCLOFCM_01968 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
GBCLOFCM_01969 1.08e-11 - - - - - - - -
GBCLOFCM_01970 1.31e-212 ypcP - - L - - - 5'3' exonuclease
GBCLOFCM_01971 5.23e-05 - - - - ko:K06429 - ko00000 -
GBCLOFCM_01972 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
GBCLOFCM_01973 8.47e-149 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GBCLOFCM_01974 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
GBCLOFCM_01975 1.54e-37 ypeQ - - S - - - Zinc-finger
GBCLOFCM_01976 1.5e-40 - - - S - - - Protein of unknown function (DUF2564)
GBCLOFCM_01977 1.17e-22 degR - - - - - - -
GBCLOFCM_01978 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GBCLOFCM_01979 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GBCLOFCM_01980 4.32e-158 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBCLOFCM_01981 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
GBCLOFCM_01982 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
GBCLOFCM_01983 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
GBCLOFCM_01984 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GBCLOFCM_01985 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
GBCLOFCM_01986 2.92e-185 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
GBCLOFCM_01987 3.47e-148 ypjP - - S - - - YpjP-like protein
GBCLOFCM_01988 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GBCLOFCM_01989 2.34e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GBCLOFCM_01990 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GBCLOFCM_01991 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GBCLOFCM_01992 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
GBCLOFCM_01993 1.4e-236 yplP - - K - - - Transcriptional regulator
GBCLOFCM_01994 2.33e-176 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBCLOFCM_01995 3.63e-105 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBCLOFCM_01996 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
GBCLOFCM_01997 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GBCLOFCM_01998 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
GBCLOFCM_01999 1.95e-128 ypmS - - S - - - protein conserved in bacteria
GBCLOFCM_02000 2.13e-40 ypmT - - S - - - Uncharacterized ympT
GBCLOFCM_02001 5.77e-289 mepA - - V - - - MATE efflux family protein
GBCLOFCM_02002 4.14e-94 ypoP - - K - - - transcriptional
GBCLOFCM_02003 8.73e-118 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBCLOFCM_02004 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GBCLOFCM_02005 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GBCLOFCM_02006 1.39e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
GBCLOFCM_02007 4.7e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
GBCLOFCM_02008 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
GBCLOFCM_02009 6.14e-59 cgeC - - - ko:K06321 - ko00000 -
GBCLOFCM_02010 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
GBCLOFCM_02011 1.56e-181 yiiD - - K ko:K06323 - ko00000 acetyltransferase
GBCLOFCM_02013 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GBCLOFCM_02014 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GBCLOFCM_02015 4.49e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GBCLOFCM_02016 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
GBCLOFCM_02017 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
GBCLOFCM_02018 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
GBCLOFCM_02019 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
GBCLOFCM_02020 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
GBCLOFCM_02021 1.29e-159 yodN - - - - - - -
GBCLOFCM_02022 5.18e-34 yozD - - S - - - YozD-like protein
GBCLOFCM_02023 1.91e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GBCLOFCM_02024 1.17e-71 yodL - - S - - - YodL-like
GBCLOFCM_02025 2.08e-12 - - - - - - - -
GBCLOFCM_02026 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GBCLOFCM_02027 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GBCLOFCM_02028 2.93e-42 yodI - - - - - - -
GBCLOFCM_02029 3.69e-167 yodH - - Q - - - Methyltransferase
GBCLOFCM_02030 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GBCLOFCM_02031 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBCLOFCM_02032 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
GBCLOFCM_02033 1.38e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GBCLOFCM_02034 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
GBCLOFCM_02035 4.53e-139 yodC - - C - - - nitroreductase
GBCLOFCM_02036 2.63e-73 yodB - - K - - - transcriptional
GBCLOFCM_02037 5.64e-84 iolK - - S - - - tautomerase
GBCLOFCM_02038 2.65e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GBCLOFCM_02039 5.59e-14 - - - - - - - -
GBCLOFCM_02040 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
GBCLOFCM_02041 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
GBCLOFCM_02042 1.85e-58 - - - - - - - -
GBCLOFCM_02043 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
GBCLOFCM_02044 3.5e-13 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
GBCLOFCM_02045 3.3e-128 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
GBCLOFCM_02046 1.68e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GBCLOFCM_02047 8.38e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
GBCLOFCM_02049 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GBCLOFCM_02050 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
GBCLOFCM_02051 6.16e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GBCLOFCM_02052 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GBCLOFCM_02053 2.69e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
GBCLOFCM_02054 0.0 yojO - - P - - - Von Willebrand factor
GBCLOFCM_02055 8.72e-206 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GBCLOFCM_02056 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GBCLOFCM_02057 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GBCLOFCM_02058 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
GBCLOFCM_02059 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GBCLOFCM_02060 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
GBCLOFCM_02061 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
GBCLOFCM_02062 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GBCLOFCM_02063 1.61e-08 yozC - - - - - - -
GBCLOFCM_02064 2.17e-74 yozO - - S - - - Bacterial PH domain
GBCLOFCM_02065 1.83e-49 yocN - - - - - - -
GBCLOFCM_02066 2.94e-55 yozN - - - - - - -
GBCLOFCM_02067 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GBCLOFCM_02068 7.29e-46 - - - - - - - -
GBCLOFCM_02069 3.02e-70 yocL - - - - - - -
GBCLOFCM_02070 4.07e-107 yocK - - T - - - general stress protein
GBCLOFCM_02071 8.45e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GBCLOFCM_02073 9.69e-229 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GBCLOFCM_02074 3.32e-172 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GBCLOFCM_02075 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
GBCLOFCM_02076 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_02077 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_02078 3.28e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
GBCLOFCM_02079 3.88e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
GBCLOFCM_02080 1.8e-120 yocC - - - - - - -
GBCLOFCM_02081 2.6e-185 - - - - - - - -
GBCLOFCM_02082 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
GBCLOFCM_02083 1.56e-126 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GBCLOFCM_02084 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
GBCLOFCM_02085 3.01e-120 yobW - - - - - - -
GBCLOFCM_02086 5.41e-225 yobV - - K - - - WYL domain
GBCLOFCM_02087 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
GBCLOFCM_02088 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GBCLOFCM_02089 4.91e-124 yobS - - K - - - Transcriptional regulator
GBCLOFCM_02090 4.16e-180 - - - J - - - FR47-like protein
GBCLOFCM_02091 6.36e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
GBCLOFCM_02092 1.82e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
GBCLOFCM_02093 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
GBCLOFCM_02094 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
GBCLOFCM_02095 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GBCLOFCM_02096 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
GBCLOFCM_02097 1.09e-134 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
GBCLOFCM_02098 0.0 aga 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
GBCLOFCM_02099 2.4e-20 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_02100 7.48e-64 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_02101 2.16e-128 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GBCLOFCM_02102 4.23e-50 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GBCLOFCM_02104 1.23e-272 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
GBCLOFCM_02105 3.14e-167 - - - K - - - Bacterial regulatory proteins, lacI family
GBCLOFCM_02106 2.59e-220 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GBCLOFCM_02107 2.71e-29 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBCLOFCM_02108 1.48e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GBCLOFCM_02109 1.54e-84 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
GBCLOFCM_02111 1.87e-74 - - - K - - - Helix-turn-helix
GBCLOFCM_02112 6.27e-51 - - - S - - - TM2 domain
GBCLOFCM_02114 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
GBCLOFCM_02115 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
GBCLOFCM_02118 1.21e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
GBCLOFCM_02119 5.08e-149 lin0465 - - S - - - DJ-1/PfpI family
GBCLOFCM_02120 2.22e-54 yoaW - - - - - - -
GBCLOFCM_02121 8.71e-200 yoaV - - EG - - - EamA-like transporter family
GBCLOFCM_02122 6.67e-203 yoaU - - K - - - LysR substrate binding domain
GBCLOFCM_02123 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
GBCLOFCM_02124 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02125 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
GBCLOFCM_02126 7.28e-186 yoaR - - V - - - vancomycin resistance protein
GBCLOFCM_02127 3.09e-37 - - - - - - - -
GBCLOFCM_02128 7.77e-66 - - - - - - - -
GBCLOFCM_02130 6.41e-56 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
GBCLOFCM_02131 9.48e-188 yoaP - - K - - - YoaP-like
GBCLOFCM_02133 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GBCLOFCM_02135 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GBCLOFCM_02136 4.11e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
GBCLOFCM_02137 1.79e-145 yoaK - - S - - - Membrane
GBCLOFCM_02138 1.06e-170 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
GBCLOFCM_02139 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
GBCLOFCM_02140 5.35e-309 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
GBCLOFCM_02141 1.13e-59 - - - S - - - Protein of unknown function (DUF4025)
GBCLOFCM_02142 1.25e-20 - - - - - - - -
GBCLOFCM_02144 7.24e-45 yoaF - - - - - - -
GBCLOFCM_02145 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GBCLOFCM_02146 1.43e-235 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBCLOFCM_02147 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
GBCLOFCM_02148 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
GBCLOFCM_02149 6.7e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_02150 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
GBCLOFCM_02151 1.25e-121 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GBCLOFCM_02152 1.39e-164 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GBCLOFCM_02153 2.81e-123 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBCLOFCM_02154 1.73e-172 yoxB - - - - - - -
GBCLOFCM_02155 1.1e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
GBCLOFCM_02156 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_02157 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GBCLOFCM_02158 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBCLOFCM_02159 4.51e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBCLOFCM_02160 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02161 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
GBCLOFCM_02162 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GBCLOFCM_02163 1.7e-236 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GBCLOFCM_02164 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02165 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GBCLOFCM_02166 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
GBCLOFCM_02167 4.89e-38 - - - L - - - Integrase
GBCLOFCM_02168 6.24e-59 - - - L - - - Integrase
GBCLOFCM_02170 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
GBCLOFCM_02171 9.8e-313 yoeA - - V - - - MATE efflux family protein
GBCLOFCM_02172 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GBCLOFCM_02173 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GBCLOFCM_02174 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02175 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02176 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02177 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02178 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02179 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02180 2.47e-80 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_02181 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
GBCLOFCM_02182 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
GBCLOFCM_02183 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
GBCLOFCM_02184 1.89e-51 - - - S - - - Family of unknown function (DUF5367)
GBCLOFCM_02185 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GBCLOFCM_02186 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GBCLOFCM_02187 8.43e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
GBCLOFCM_02188 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
GBCLOFCM_02189 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
GBCLOFCM_02190 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
GBCLOFCM_02191 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GBCLOFCM_02192 1.82e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
GBCLOFCM_02193 2.01e-134 yngC - - S - - - membrane-associated protein
GBCLOFCM_02194 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GBCLOFCM_02195 1.72e-103 yngA - - S - - - membrane
GBCLOFCM_02196 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GBCLOFCM_02197 1.18e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
GBCLOFCM_02199 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
GBCLOFCM_02200 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GBCLOFCM_02201 1.06e-75 ynfC - - - - - - -
GBCLOFCM_02202 1.82e-18 - - - - - - - -
GBCLOFCM_02203 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBCLOFCM_02204 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBCLOFCM_02205 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
GBCLOFCM_02206 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GBCLOFCM_02207 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
GBCLOFCM_02208 9.46e-71 yneQ - - - - - - -
GBCLOFCM_02209 6.05e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
GBCLOFCM_02210 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
GBCLOFCM_02212 9.26e-10 - - - S - - - Fur-regulated basic protein B
GBCLOFCM_02213 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GBCLOFCM_02214 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GBCLOFCM_02215 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
GBCLOFCM_02216 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
GBCLOFCM_02217 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
GBCLOFCM_02218 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
GBCLOFCM_02219 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
GBCLOFCM_02220 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
GBCLOFCM_02221 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
GBCLOFCM_02222 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
GBCLOFCM_02223 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
GBCLOFCM_02224 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
GBCLOFCM_02225 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBCLOFCM_02226 1.15e-43 ynzC - - S - - - UPF0291 protein
GBCLOFCM_02227 7.01e-91 yneB - - L - - - resolvase
GBCLOFCM_02228 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GBCLOFCM_02229 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GBCLOFCM_02230 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GBCLOFCM_02231 4.42e-95 yndM - - S - - - Protein of unknown function (DUF2512)
GBCLOFCM_02232 5.63e-176 yndL - - S - - - Replication protein
GBCLOFCM_02234 0.0 yndJ - - S - - - YndJ-like protein
GBCLOFCM_02235 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
GBCLOFCM_02236 5.29e-198 yndG - - S - - - DoxX-like family
GBCLOFCM_02237 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
GBCLOFCM_02238 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
GBCLOFCM_02239 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GBCLOFCM_02242 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
GBCLOFCM_02243 8.92e-96 - - - - - - - -
GBCLOFCM_02244 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
GBCLOFCM_02247 2.11e-170 - - - S - - - Domain of unknown function, YrpD
GBCLOFCM_02249 3.75e-208 - - - S - - - Thymidylate synthase
GBCLOFCM_02252 3.07e-21 - - - - - - - -
GBCLOFCM_02253 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
GBCLOFCM_02254 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
GBCLOFCM_02255 1.77e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBCLOFCM_02256 8.56e-312 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GBCLOFCM_02257 2.51e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
GBCLOFCM_02258 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
GBCLOFCM_02259 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
GBCLOFCM_02260 1.56e-266 xylR - - GK - - - ROK family
GBCLOFCM_02261 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GBCLOFCM_02262 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
GBCLOFCM_02263 4.15e-108 - - - E - - - phosphoribosylanthranilate isomerase activity
GBCLOFCM_02266 1.28e-141 - - - S - - - Domain of unknown function (DUF3885)
GBCLOFCM_02267 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GBCLOFCM_02269 1.21e-90 - - - S - - - CAAX protease self-immunity
GBCLOFCM_02271 5.84e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
GBCLOFCM_02272 1.1e-24 ynaC - - - - - - -
GBCLOFCM_02273 2.39e-115 - - - G - - - SMI1-KNR4 cell-wall
GBCLOFCM_02274 4.15e-49 - - - - - - - -
GBCLOFCM_02275 5.18e-40 - - - - - - - -
GBCLOFCM_02276 4.18e-14 - - - - - - - -
GBCLOFCM_02277 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GBCLOFCM_02278 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
GBCLOFCM_02279 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GBCLOFCM_02280 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBCLOFCM_02281 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
GBCLOFCM_02282 6.69e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GBCLOFCM_02283 2.24e-141 - - - - - - - -
GBCLOFCM_02284 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBCLOFCM_02285 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBCLOFCM_02286 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
GBCLOFCM_02287 1.2e-30 ymzA - - - - - - -
GBCLOFCM_02288 1.63e-31 - - - - - - - -
GBCLOFCM_02289 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GBCLOFCM_02290 1.66e-214 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GBCLOFCM_02291 5.41e-76 ymaF - - S - - - YmaF family
GBCLOFCM_02293 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GBCLOFCM_02294 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
GBCLOFCM_02295 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
GBCLOFCM_02296 3.96e-163 ymaC - - S - - - Replication protein
GBCLOFCM_02298 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
GBCLOFCM_02299 4.45e-51 - - - S - - - Metallo-beta-lactamase superfamily
GBCLOFCM_02300 2.5e-135 - - - S - - - Metallo-beta-lactamase superfamily
GBCLOFCM_02301 8.03e-81 ymzB - - - - - - -
GBCLOFCM_02302 7.57e-268 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GBCLOFCM_02303 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
GBCLOFCM_02304 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02305 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02306 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02307 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02308 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02309 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02310 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02311 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
GBCLOFCM_02312 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
GBCLOFCM_02313 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GBCLOFCM_02314 8.65e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
GBCLOFCM_02315 1.44e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
GBCLOFCM_02316 9.3e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
GBCLOFCM_02317 8.43e-301 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GBCLOFCM_02318 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
GBCLOFCM_02319 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GBCLOFCM_02320 4.02e-237 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
GBCLOFCM_02322 8.82e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GBCLOFCM_02323 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
GBCLOFCM_02324 2.94e-141 pksA - - K - - - Transcriptional regulator
GBCLOFCM_02325 1.38e-127 ymcC - - S - - - Membrane
GBCLOFCM_02326 6.68e-92 - - - S - - - Regulatory protein YrvL
GBCLOFCM_02327 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GBCLOFCM_02328 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GBCLOFCM_02329 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
GBCLOFCM_02330 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
GBCLOFCM_02331 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GBCLOFCM_02332 4.64e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GBCLOFCM_02333 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GBCLOFCM_02334 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
GBCLOFCM_02335 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
GBCLOFCM_02336 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GBCLOFCM_02337 4e-280 pbpX - - V - - - Beta-lactamase
GBCLOFCM_02338 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBCLOFCM_02339 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GBCLOFCM_02340 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBCLOFCM_02341 1.76e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
GBCLOFCM_02342 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
GBCLOFCM_02343 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
GBCLOFCM_02344 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GBCLOFCM_02345 7.6e-306 ymfH - - S - - - zinc protease
GBCLOFCM_02346 3.17e-297 albE - - S - - - Peptidase M16
GBCLOFCM_02347 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_02348 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02349 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GBCLOFCM_02350 4.94e-44 - - - S - - - YlzJ-like protein
GBCLOFCM_02351 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
GBCLOFCM_02352 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBCLOFCM_02353 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBCLOFCM_02354 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GBCLOFCM_02355 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GBCLOFCM_02356 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GBCLOFCM_02357 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
GBCLOFCM_02358 1.53e-56 ymxH - - S - - - YlmC YmxH family
GBCLOFCM_02359 4.64e-295 mlpA - - S - - - Belongs to the peptidase M16 family
GBCLOFCM_02360 7.18e-233 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
GBCLOFCM_02361 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GBCLOFCM_02362 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GBCLOFCM_02363 9.42e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GBCLOFCM_02364 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBCLOFCM_02365 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GBCLOFCM_02366 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
GBCLOFCM_02367 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GBCLOFCM_02368 6.16e-63 ylxQ - - J - - - ribosomal protein
GBCLOFCM_02369 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
GBCLOFCM_02370 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GBCLOFCM_02371 2.22e-103 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GBCLOFCM_02372 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBCLOFCM_02373 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GBCLOFCM_02374 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GBCLOFCM_02375 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GBCLOFCM_02376 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GBCLOFCM_02377 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBCLOFCM_02378 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GBCLOFCM_02379 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GBCLOFCM_02380 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GBCLOFCM_02381 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GBCLOFCM_02382 6.62e-99 ylxL - - - - - - -
GBCLOFCM_02383 9.34e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_02384 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GBCLOFCM_02385 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GBCLOFCM_02386 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
GBCLOFCM_02387 1.3e-135 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
GBCLOFCM_02388 8.82e-256 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
GBCLOFCM_02389 1.05e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GBCLOFCM_02390 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
GBCLOFCM_02391 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
GBCLOFCM_02392 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GBCLOFCM_02393 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GBCLOFCM_02394 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
GBCLOFCM_02395 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
GBCLOFCM_02396 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
GBCLOFCM_02397 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
GBCLOFCM_02398 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
GBCLOFCM_02399 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GBCLOFCM_02400 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GBCLOFCM_02401 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
GBCLOFCM_02402 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
GBCLOFCM_02403 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
GBCLOFCM_02404 3.22e-269 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
GBCLOFCM_02405 5.17e-30 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
GBCLOFCM_02406 9.63e-82 ylxF - - S - - - MgtE intracellular N domain
GBCLOFCM_02407 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
GBCLOFCM_02408 1.17e-305 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GBCLOFCM_02409 1.35e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
GBCLOFCM_02410 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GBCLOFCM_02411 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
GBCLOFCM_02412 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
GBCLOFCM_02413 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
GBCLOFCM_02414 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GBCLOFCM_02415 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GBCLOFCM_02416 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GBCLOFCM_02417 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GBCLOFCM_02418 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
GBCLOFCM_02419 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GBCLOFCM_02420 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBCLOFCM_02421 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
GBCLOFCM_02422 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GBCLOFCM_02423 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GBCLOFCM_02424 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
GBCLOFCM_02425 0.0 ylqG - - - - - - -
GBCLOFCM_02426 1.37e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBCLOFCM_02427 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GBCLOFCM_02428 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GBCLOFCM_02429 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GBCLOFCM_02430 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GBCLOFCM_02431 1.14e-78 ylqD - - S - - - YlqD protein
GBCLOFCM_02432 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GBCLOFCM_02433 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GBCLOFCM_02434 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GBCLOFCM_02435 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GBCLOFCM_02436 6.2e-108 - - - - - - - -
GBCLOFCM_02437 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GBCLOFCM_02438 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GBCLOFCM_02439 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GBCLOFCM_02440 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBCLOFCM_02441 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GBCLOFCM_02442 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GBCLOFCM_02443 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GBCLOFCM_02444 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GBCLOFCM_02445 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GBCLOFCM_02446 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GBCLOFCM_02447 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GBCLOFCM_02448 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
GBCLOFCM_02449 3.65e-78 yloU - - S - - - protein conserved in bacteria
GBCLOFCM_02450 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GBCLOFCM_02451 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GBCLOFCM_02452 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GBCLOFCM_02453 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GBCLOFCM_02454 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GBCLOFCM_02455 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GBCLOFCM_02456 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GBCLOFCM_02457 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBCLOFCM_02458 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBCLOFCM_02459 2.38e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GBCLOFCM_02460 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBCLOFCM_02461 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GBCLOFCM_02462 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GBCLOFCM_02463 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GBCLOFCM_02464 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
GBCLOFCM_02465 1.19e-201 yloC - - S - - - stress-induced protein
GBCLOFCM_02466 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
GBCLOFCM_02467 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
GBCLOFCM_02468 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
GBCLOFCM_02469 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
GBCLOFCM_02470 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GBCLOFCM_02471 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GBCLOFCM_02472 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GBCLOFCM_02473 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
GBCLOFCM_02474 3.51e-175 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GBCLOFCM_02476 5.18e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GBCLOFCM_02477 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GBCLOFCM_02478 2.2e-223 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GBCLOFCM_02479 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GBCLOFCM_02480 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
GBCLOFCM_02481 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GBCLOFCM_02482 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GBCLOFCM_02483 3.46e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GBCLOFCM_02484 5.32e-270 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
GBCLOFCM_02485 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GBCLOFCM_02486 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GBCLOFCM_02487 6.39e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GBCLOFCM_02488 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
GBCLOFCM_02489 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBCLOFCM_02490 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
GBCLOFCM_02491 8.64e-178 ylmH - - S - - - conserved protein, contains S4-like domain
GBCLOFCM_02492 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
GBCLOFCM_02493 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GBCLOFCM_02494 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GBCLOFCM_02495 3.07e-202 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
GBCLOFCM_02496 1.46e-50 ylmC - - S - - - sporulation protein
GBCLOFCM_02497 2.01e-313 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
GBCLOFCM_02498 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GBCLOFCM_02499 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_02500 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_02501 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GBCLOFCM_02502 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
GBCLOFCM_02503 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GBCLOFCM_02504 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GBCLOFCM_02505 5.37e-76 sbp - - S - - - small basic protein
GBCLOFCM_02506 2.97e-141 ylxX - - S - - - protein conserved in bacteria
GBCLOFCM_02507 4.5e-142 ylxW - - S - - - protein conserved in bacteria
GBCLOFCM_02508 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GBCLOFCM_02509 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
GBCLOFCM_02510 5.4e-99 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBCLOFCM_02511 8.23e-80 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBCLOFCM_02512 1e-23 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBCLOFCM_02513 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GBCLOFCM_02514 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GBCLOFCM_02515 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GBCLOFCM_02516 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBCLOFCM_02517 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
GBCLOFCM_02518 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GBCLOFCM_02519 3.42e-68 ftsL - - D - - - Essential cell division protein
GBCLOFCM_02520 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GBCLOFCM_02521 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GBCLOFCM_02522 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GBCLOFCM_02523 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GBCLOFCM_02524 1.33e-115 ylbP - - K - - - n-acetyltransferase
GBCLOFCM_02525 3.87e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GBCLOFCM_02526 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GBCLOFCM_02527 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
GBCLOFCM_02529 9.84e-300 ylbM - - S - - - Belongs to the UPF0348 family
GBCLOFCM_02530 4.52e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GBCLOFCM_02531 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GBCLOFCM_02532 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
GBCLOFCM_02533 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GBCLOFCM_02534 7.09e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
GBCLOFCM_02535 5.1e-51 ylbG - - S - - - UPF0298 protein
GBCLOFCM_02536 4.73e-97 ylbF - - S - - - Belongs to the UPF0342 family
GBCLOFCM_02537 1.73e-48 ylbE - - S - - - YlbE-like protein
GBCLOFCM_02538 3.24e-89 ylbD - - S - - - Putative coat protein
GBCLOFCM_02539 1.36e-251 ylbC - - S - - - protein with SCP PR1 domains
GBCLOFCM_02540 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
GBCLOFCM_02541 1.61e-81 ylbA - - S - - - YugN-like family
GBCLOFCM_02542 2.98e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
GBCLOFCM_02543 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GBCLOFCM_02544 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GBCLOFCM_02545 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBCLOFCM_02546 1.31e-09 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBCLOFCM_02547 4.81e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GBCLOFCM_02548 4.88e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GBCLOFCM_02549 5.74e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GBCLOFCM_02550 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GBCLOFCM_02551 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GBCLOFCM_02552 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
GBCLOFCM_02553 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GBCLOFCM_02554 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GBCLOFCM_02555 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
GBCLOFCM_02556 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GBCLOFCM_02557 8.92e-44 ylaI - - S - - - protein conserved in bacteria
GBCLOFCM_02558 4.4e-63 ylaH - - S - - - YlaH-like protein
GBCLOFCM_02559 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GBCLOFCM_02560 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
GBCLOFCM_02561 9.96e-57 ylaE - - - - - - -
GBCLOFCM_02563 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_02564 1.44e-56 ylaB - - - - - - -
GBCLOFCM_02565 0.0 ylaA - - - - - - -
GBCLOFCM_02566 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GBCLOFCM_02567 9.64e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GBCLOFCM_02568 2.02e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
GBCLOFCM_02569 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
GBCLOFCM_02570 4.48e-35 ykzI - - - - - - -
GBCLOFCM_02571 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
GBCLOFCM_02572 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
GBCLOFCM_02573 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
GBCLOFCM_02574 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
GBCLOFCM_02575 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GBCLOFCM_02576 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GBCLOFCM_02577 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GBCLOFCM_02578 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GBCLOFCM_02579 6.54e-147 ykyA - - L - - - Putative cell-wall binding lipoprotein
GBCLOFCM_02580 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GBCLOFCM_02581 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GBCLOFCM_02582 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
GBCLOFCM_02583 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
GBCLOFCM_02584 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBCLOFCM_02585 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GBCLOFCM_02586 2.38e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GBCLOFCM_02587 1.78e-205 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
GBCLOFCM_02588 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GBCLOFCM_02589 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
GBCLOFCM_02590 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
GBCLOFCM_02591 1.09e-18 - - - S - - - Uncharacterized protein YkpC
GBCLOFCM_02592 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
GBCLOFCM_02593 4.75e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GBCLOFCM_02594 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GBCLOFCM_02595 5.43e-52 ykoA - - - - - - -
GBCLOFCM_02596 7.03e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GBCLOFCM_02597 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GBCLOFCM_02598 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
GBCLOFCM_02599 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02600 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GBCLOFCM_02601 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_02602 2.34e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBCLOFCM_02603 1.31e-150 yknW - - S - - - Yip1 domain
GBCLOFCM_02604 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_02605 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_02606 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GBCLOFCM_02607 2.22e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
GBCLOFCM_02608 7.8e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GBCLOFCM_02609 8.3e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
GBCLOFCM_02610 1.79e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GBCLOFCM_02611 4.38e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GBCLOFCM_02612 6.97e-200 yknT - - - ko:K06437 - ko00000 -
GBCLOFCM_02613 4.71e-122 rok - - K - - - Repressor of ComK
GBCLOFCM_02614 1.47e-104 ykuV - - CO - - - thiol-disulfide
GBCLOFCM_02615 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
GBCLOFCM_02616 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
GBCLOFCM_02617 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
GBCLOFCM_02618 1.27e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GBCLOFCM_02619 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GBCLOFCM_02620 6.65e-96 fld - - C ko:K03839 - ko00000 Flavodoxin
GBCLOFCM_02621 2.89e-221 ykuO - - - - - - -
GBCLOFCM_02622 2.59e-112 - - - C ko:K03839 - ko00000 Flavodoxin domain
GBCLOFCM_02623 6.52e-216 ccpC - - K - - - Transcriptional regulator
GBCLOFCM_02624 5.15e-100 ykuL - - S - - - CBS domain
GBCLOFCM_02625 7.83e-38 ykzF - - S - - - Antirepressor AbbA
GBCLOFCM_02626 5.99e-112 - - - S ko:K09776 - ko00000 Ribonuclease H-like
GBCLOFCM_02627 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
GBCLOFCM_02628 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
GBCLOFCM_02630 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
GBCLOFCM_02631 5.65e-160 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_02632 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
GBCLOFCM_02633 2.38e-114 ykuD - - S - - - protein conserved in bacteria
GBCLOFCM_02634 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_02635 3.71e-110 ykyB - - S - - - YkyB-like protein
GBCLOFCM_02636 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
GBCLOFCM_02637 1.05e-22 - - - - - - - -
GBCLOFCM_02638 1.4e-281 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GBCLOFCM_02639 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_02640 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GBCLOFCM_02641 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
GBCLOFCM_02642 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GBCLOFCM_02643 3.82e-234 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_02644 1.59e-123 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_02645 1.4e-108 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_02646 2.06e-26 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_02647 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
GBCLOFCM_02648 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_02649 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBCLOFCM_02650 1.65e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
GBCLOFCM_02651 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_02652 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
GBCLOFCM_02654 3.28e-230 ykvZ - - K - - - Transcriptional regulator
GBCLOFCM_02655 1.58e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GBCLOFCM_02656 3.99e-09 - - - - - - - -
GBCLOFCM_02657 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GBCLOFCM_02658 5.79e-117 stoA - - CO - - - thiol-disulfide
GBCLOFCM_02659 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_02660 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
GBCLOFCM_02661 2.6e-39 - - - - - - - -
GBCLOFCM_02662 5.43e-35 ykvS - - S - - - protein conserved in bacteria
GBCLOFCM_02663 2.2e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
GBCLOFCM_02664 4.3e-205 - - - G - - - Glycosyl hydrolases family 18
GBCLOFCM_02665 1.07e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
GBCLOFCM_02666 4.27e-272 - - - M - - - Glycosyl transferases group 1
GBCLOFCM_02667 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_02668 2.8e-81 ykvN - - K - - - Transcriptional regulator
GBCLOFCM_02669 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GBCLOFCM_02670 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GBCLOFCM_02671 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
GBCLOFCM_02672 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GBCLOFCM_02673 4.76e-227 ykvI - - S - - - membrane
GBCLOFCM_02674 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GBCLOFCM_02675 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GBCLOFCM_02676 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GBCLOFCM_02677 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
GBCLOFCM_02678 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GBCLOFCM_02679 5.84e-95 eag - - - - - - -
GBCLOFCM_02681 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
GBCLOFCM_02682 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GBCLOFCM_02683 7.5e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GBCLOFCM_02684 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GBCLOFCM_02685 3.96e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GBCLOFCM_02686 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GBCLOFCM_02687 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GBCLOFCM_02688 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GBCLOFCM_02689 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GBCLOFCM_02691 1.12e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBCLOFCM_02692 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_02693 1.93e-243 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
GBCLOFCM_02694 8.76e-29 ykzE - - - - - - -
GBCLOFCM_02696 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
GBCLOFCM_02697 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GBCLOFCM_02698 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
GBCLOFCM_02699 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
GBCLOFCM_02700 1.27e-209 rsgI - - S - - - Anti-sigma factor N-terminus
GBCLOFCM_02701 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_02702 3.8e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GBCLOFCM_02703 1.71e-143 ykoX - - S - - - membrane-associated protein
GBCLOFCM_02704 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
GBCLOFCM_02705 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GBCLOFCM_02706 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
GBCLOFCM_02707 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
GBCLOFCM_02708 0.0 ykoS - - - - - - -
GBCLOFCM_02709 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GBCLOFCM_02710 2.29e-125 ykoP - - G - - - polysaccharide deacetylase
GBCLOFCM_02711 1.83e-279 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
GBCLOFCM_02712 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
GBCLOFCM_02713 2.51e-35 ykoL - - - - - - -
GBCLOFCM_02714 3.3e-25 - - - - - - - -
GBCLOFCM_02715 1.49e-70 tnrA - - K - - - transcriptional
GBCLOFCM_02716 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
GBCLOFCM_02718 1.45e-08 - - - - - - - -
GBCLOFCM_02719 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GBCLOFCM_02720 4.56e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
GBCLOFCM_02721 3.5e-306 ykoH - - T - - - Histidine kinase
GBCLOFCM_02722 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_02723 2.97e-143 ykoF - - S - - - YKOF-related Family
GBCLOFCM_02724 1.14e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GBCLOFCM_02725 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_02726 2.2e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GBCLOFCM_02727 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GBCLOFCM_02728 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GBCLOFCM_02729 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBCLOFCM_02730 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
GBCLOFCM_02732 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
GBCLOFCM_02733 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
GBCLOFCM_02734 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
GBCLOFCM_02735 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GBCLOFCM_02736 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBCLOFCM_02737 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GBCLOFCM_02738 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
GBCLOFCM_02739 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
GBCLOFCM_02740 1.46e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBCLOFCM_02741 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
GBCLOFCM_02742 6.55e-166 ykjA - - S - - - Protein of unknown function (DUF421)
GBCLOFCM_02743 3.55e-14 - - - - - - - -
GBCLOFCM_02744 1.53e-288 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GBCLOFCM_02745 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
GBCLOFCM_02746 3.4e-172 ykgA - - E - - - Amidinotransferase
GBCLOFCM_02747 1.34e-259 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
GBCLOFCM_02748 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02749 3.81e-89 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GBCLOFCM_02750 1.49e-95 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GBCLOFCM_02751 1.14e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GBCLOFCM_02752 8.23e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GBCLOFCM_02754 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GBCLOFCM_02755 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02756 4.28e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02757 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02758 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
GBCLOFCM_02759 4.06e-179 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
GBCLOFCM_02760 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBCLOFCM_02762 9.02e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GBCLOFCM_02763 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GBCLOFCM_02765 2.82e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GBCLOFCM_02766 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
GBCLOFCM_02767 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
GBCLOFCM_02768 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
GBCLOFCM_02769 4.83e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
GBCLOFCM_02770 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
GBCLOFCM_02771 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GBCLOFCM_02772 2.33e-52 xhlB - - S - - - SPP1 phage holin
GBCLOFCM_02773 2.21e-51 xhlA - - S - - - Haemolysin XhlA
GBCLOFCM_02774 3.28e-193 xepA - - - - - - -
GBCLOFCM_02775 4.47e-31 xkdX - - - - - - -
GBCLOFCM_02776 1.23e-57 xkdW - - S - - - XkdW protein
GBCLOFCM_02777 3.53e-224 - - - - - - - -
GBCLOFCM_02778 4.43e-56 - - - - - - - -
GBCLOFCM_02779 2.27e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
GBCLOFCM_02780 6.23e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GBCLOFCM_02781 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
GBCLOFCM_02782 6.14e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
GBCLOFCM_02783 2.31e-232 xkdQ - - G - - - NLP P60 protein
GBCLOFCM_02784 3.57e-145 xkdP - - S - - - Lysin motif
GBCLOFCM_02785 0.0 xkdO - - L - - - Transglycosylase SLT domain
GBCLOFCM_02786 1.18e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
GBCLOFCM_02787 6.01e-99 xkdM - - S - - - Phage tail tube protein
GBCLOFCM_02788 1.82e-12 xkdK - - S - - - Phage tail sheath C-terminal domain
GBCLOFCM_02789 1.8e-220 xkdK - - S - - - Phage tail sheath C-terminal domain
GBCLOFCM_02790 9.05e-70 xkdK - - S - - - Phage tail sheath C-terminal domain
GBCLOFCM_02791 6.78e-100 xkdJ - - - - - - -
GBCLOFCM_02792 1.13e-112 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
GBCLOFCM_02793 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
GBCLOFCM_02794 3.16e-80 yqbG - - S - - - Protein of unknown function (DUF3199)
GBCLOFCM_02795 3.91e-217 xkdG - - S - - - Phage capsid family
GBCLOFCM_02796 5.47e-174 xkdF3 - - L - - - Putative phage serine protease XkdF
GBCLOFCM_02797 0.0 yqbA - - S - - - portal protein
GBCLOFCM_02798 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
GBCLOFCM_02799 3.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
GBCLOFCM_02800 2.83e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GBCLOFCM_02804 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
GBCLOFCM_02805 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
GBCLOFCM_02807 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
GBCLOFCM_02808 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
GBCLOFCM_02809 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
GBCLOFCM_02810 5.99e-143 yjqB - - S - - - Pfam:DUF867
GBCLOFCM_02811 1.35e-80 yjqA - - S - - - Bacterial PH domain
GBCLOFCM_02812 5.34e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GBCLOFCM_02813 1.79e-55 - - - S - - - YCII-related domain
GBCLOFCM_02815 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GBCLOFCM_02816 2.48e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
GBCLOFCM_02817 6.55e-98 yjoA - - S - - - DinB family
GBCLOFCM_02818 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
GBCLOFCM_02819 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GBCLOFCM_02820 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
GBCLOFCM_02821 1.99e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
GBCLOFCM_02822 3.76e-287 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
GBCLOFCM_02823 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GBCLOFCM_02824 1.37e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
GBCLOFCM_02825 1.71e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
GBCLOFCM_02826 1.71e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
GBCLOFCM_02827 2.5e-313 - - - G ko:K03292 - ko00000 symporter YjmB
GBCLOFCM_02828 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
GBCLOFCM_02829 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GBCLOFCM_02830 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
GBCLOFCM_02831 5.79e-117 yjlB - - S - - - Cupin domain
GBCLOFCM_02832 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
GBCLOFCM_02833 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GBCLOFCM_02834 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
GBCLOFCM_02835 4.82e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GBCLOFCM_02836 1.11e-41 - - - - - - - -
GBCLOFCM_02837 1.02e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GBCLOFCM_02838 1.11e-284 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GBCLOFCM_02840 3.17e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GBCLOFCM_02842 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
GBCLOFCM_02843 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GBCLOFCM_02844 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
GBCLOFCM_02845 3.95e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
GBCLOFCM_02846 2.98e-215 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
GBCLOFCM_02847 4.62e-29 yjfB - - S - - - Putative motility protein
GBCLOFCM_02848 6.11e-106 - - - S - - - Protein of unknown function (DUF2690)
GBCLOFCM_02849 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
GBCLOFCM_02851 3.07e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GBCLOFCM_02852 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
GBCLOFCM_02853 3.55e-39 - - - S - - - Domain of unknown function (DUF4177)
GBCLOFCM_02854 2.38e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBCLOFCM_02856 2.09e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GBCLOFCM_02857 3.93e-77 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GBCLOFCM_02858 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GBCLOFCM_02859 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_02860 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
GBCLOFCM_02861 0.000759 - - - - - - - -
GBCLOFCM_02862 6.61e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_02863 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
GBCLOFCM_02864 6.49e-42 yqaS - - L - - - DNA packaging
GBCLOFCM_02866 2.84e-68 - - - L - - - Transposase
GBCLOFCM_02868 1.52e-68 yjcN - - - - - - -
GBCLOFCM_02869 3.75e-269 - - - S - - - Putative amidase domain
GBCLOFCM_02872 1.37e-269 yjcL - - S - - - Protein of unknown function (DUF819)
GBCLOFCM_02873 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
GBCLOFCM_02874 2.14e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GBCLOFCM_02875 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GBCLOFCM_02876 8.47e-88 - - - - - - - -
GBCLOFCM_02877 1.87e-163 - - - V - - - COG1401 GTPase subunit of restriction endonuclease
GBCLOFCM_02880 1.83e-175 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
GBCLOFCM_02881 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
GBCLOFCM_02882 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_02883 6.31e-51 - - - - - - - -
GBCLOFCM_02884 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GBCLOFCM_02885 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
GBCLOFCM_02888 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
GBCLOFCM_02889 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
GBCLOFCM_02890 9.3e-32 cotW - - - ko:K06341 - ko00000 -
GBCLOFCM_02891 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
GBCLOFCM_02892 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
GBCLOFCM_02893 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
GBCLOFCM_02894 1.55e-105 yjbX - - S - - - Spore coat protein
GBCLOFCM_02895 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GBCLOFCM_02896 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GBCLOFCM_02897 7.21e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GBCLOFCM_02898 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GBCLOFCM_02899 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
GBCLOFCM_02900 6.31e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
GBCLOFCM_02901 5.7e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
GBCLOFCM_02902 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GBCLOFCM_02903 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GBCLOFCM_02904 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GBCLOFCM_02905 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GBCLOFCM_02906 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBCLOFCM_02907 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
GBCLOFCM_02908 3.77e-81 yjbL - - S - - - Belongs to the UPF0738 family
GBCLOFCM_02909 7.32e-130 yjbK - - S - - - protein conserved in bacteria
GBCLOFCM_02910 2.94e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GBCLOFCM_02911 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
GBCLOFCM_02912 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GBCLOFCM_02913 2.68e-28 - - - - - - - -
GBCLOFCM_02914 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GBCLOFCM_02915 1.03e-280 coiA - - S ko:K06198 - ko00000 Competence protein
GBCLOFCM_02916 6.34e-147 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GBCLOFCM_02917 2.03e-143 yjbE - - P - - - Integral membrane protein TerC family
GBCLOFCM_02918 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GBCLOFCM_02919 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_02920 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
GBCLOFCM_02921 3.32e-61 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02922 5.16e-69 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02923 4.74e-46 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02924 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02925 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02926 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02927 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GBCLOFCM_02928 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
GBCLOFCM_02929 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
GBCLOFCM_02930 1.22e-164 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02931 7.94e-16 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02932 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBCLOFCM_02933 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
GBCLOFCM_02934 3.43e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02935 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GBCLOFCM_02936 3.65e-163 yjaZ - - O - - - Zn-dependent protease
GBCLOFCM_02937 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GBCLOFCM_02938 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBCLOFCM_02939 2.67e-38 yjzB - - - - - - -
GBCLOFCM_02940 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
GBCLOFCM_02941 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
GBCLOFCM_02942 3.01e-131 yjaV - - - - - - -
GBCLOFCM_02943 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
GBCLOFCM_02944 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
GBCLOFCM_02945 2.51e-39 yjzC - - S - - - YjzC-like protein
GBCLOFCM_02946 4.51e-222 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBCLOFCM_02947 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
GBCLOFCM_02948 2.16e-242 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GBCLOFCM_02949 3.81e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
GBCLOFCM_02950 7.35e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
GBCLOFCM_02951 5.42e-109 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBCLOFCM_02952 2.32e-162 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBCLOFCM_02953 7.11e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GBCLOFCM_02954 8.57e-112 yitZ - - G - - - Major Facilitator Superfamily
GBCLOFCM_02955 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
GBCLOFCM_02956 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
GBCLOFCM_02957 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
GBCLOFCM_02958 4.85e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GBCLOFCM_02959 1.52e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GBCLOFCM_02960 1.92e-08 - - - - - - - -
GBCLOFCM_02961 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
GBCLOFCM_02962 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
GBCLOFCM_02963 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GBCLOFCM_02964 1.07e-200 yitS - - S - - - protein conserved in bacteria
GBCLOFCM_02965 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GBCLOFCM_02966 6.52e-59 yitR - - S - - - Domain of unknown function (DUF3784)
GBCLOFCM_02967 1.06e-120 - - - - - - - -
GBCLOFCM_02968 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
GBCLOFCM_02969 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
GBCLOFCM_02970 1.17e-217 - - - - - - - -
GBCLOFCM_02971 4.16e-122 - - - - - - - -
GBCLOFCM_02972 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
GBCLOFCM_02973 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
GBCLOFCM_02974 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GBCLOFCM_02975 2.42e-90 - - - S - - - Acetyltransferase (GNAT) domain
GBCLOFCM_02976 5.24e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
GBCLOFCM_02977 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_02978 1.02e-281 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GBCLOFCM_02979 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GBCLOFCM_02980 1.75e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
GBCLOFCM_02981 3.49e-124 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
GBCLOFCM_02982 8.05e-22 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
GBCLOFCM_02983 1.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GBCLOFCM_02984 3.23e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GBCLOFCM_02985 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GBCLOFCM_02986 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBCLOFCM_02987 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
GBCLOFCM_02988 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_02989 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
GBCLOFCM_02990 4.92e-120 yisT - - S - - - DinB family
GBCLOFCM_02991 6.75e-245 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GBCLOFCM_02992 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GBCLOFCM_02993 3.88e-205 yisR - - K - - - Transcriptional regulator
GBCLOFCM_02994 1.01e-310 yisQ - - V - - - Mate efflux family protein
GBCLOFCM_02995 4.6e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
GBCLOFCM_02996 8.83e-114 yizA - - S - - - Damage-inducible protein DinB
GBCLOFCM_02997 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GBCLOFCM_02998 5.62e-127 yisN - - S - - - Protein of unknown function (DUF2777)
GBCLOFCM_02999 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GBCLOFCM_03000 1.02e-74 yisL - - S - - - UPF0344 protein
GBCLOFCM_03001 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GBCLOFCM_03002 2.29e-223 cotH - - M ko:K06330 - ko00000 Spore Coat
GBCLOFCM_03003 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
GBCLOFCM_03004 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
GBCLOFCM_03005 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
GBCLOFCM_03006 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
GBCLOFCM_03007 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
GBCLOFCM_03008 3.35e-87 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
GBCLOFCM_03009 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
GBCLOFCM_03010 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
GBCLOFCM_03011 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
GBCLOFCM_03012 5.69e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GBCLOFCM_03013 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GBCLOFCM_03014 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
GBCLOFCM_03015 9.3e-102 yhjR - - S - - - Rubrerythrin
GBCLOFCM_03016 3.85e-63 yhjQ - - C - - - COG1145 Ferredoxin
GBCLOFCM_03017 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
GBCLOFCM_03018 1.93e-267 - - - EGP - - - Transmembrane secretion effector
GBCLOFCM_03019 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
GBCLOFCM_03020 4.36e-239 yhjM - - K - - - Transcriptional regulator
GBCLOFCM_03021 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GBCLOFCM_03022 2.52e-203 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
GBCLOFCM_03023 5.2e-253 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GBCLOFCM_03024 1.73e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
GBCLOFCM_03025 4.68e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_03026 0.0 yhjG - - CH - - - FAD binding domain
GBCLOFCM_03027 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GBCLOFCM_03028 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
GBCLOFCM_03029 4.13e-78 yhjD - - - - - - -
GBCLOFCM_03030 6.55e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
GBCLOFCM_03031 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBCLOFCM_03032 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
GBCLOFCM_03033 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_03034 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
GBCLOFCM_03035 9.84e-45 yhzC - - S - - - IDEAL
GBCLOFCM_03036 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_03037 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
GBCLOFCM_03038 2.62e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
GBCLOFCM_03039 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GBCLOFCM_03040 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GBCLOFCM_03041 4.96e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GBCLOFCM_03042 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
GBCLOFCM_03043 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GBCLOFCM_03044 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
GBCLOFCM_03045 1.86e-103 - - - K - - - acetyltransferase
GBCLOFCM_03046 2.81e-259 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GBCLOFCM_03047 4.69e-165 yhfN - - O - - - Peptidase M48
GBCLOFCM_03048 2.51e-97 yhfN - - O - - - Peptidase M48
GBCLOFCM_03049 6.55e-84 yhfM - - - - - - -
GBCLOFCM_03050 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GBCLOFCM_03051 3.02e-143 yhfK - - GM - - - NmrA-like family
GBCLOFCM_03052 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GBCLOFCM_03053 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GBCLOFCM_03054 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GBCLOFCM_03055 6.22e-93 - - - S - - - ASCH
GBCLOFCM_03056 2.68e-253 yhfE - - G - - - peptidase M42
GBCLOFCM_03057 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
GBCLOFCM_03058 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBCLOFCM_03059 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
GBCLOFCM_03060 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_03061 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GBCLOFCM_03062 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GBCLOFCM_03063 3.17e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GBCLOFCM_03064 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GBCLOFCM_03065 2.18e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GBCLOFCM_03066 1.58e-12 - - - C - - - Rubrerythrin
GBCLOFCM_03067 8.08e-316 yhfA - - C - - - membrane
GBCLOFCM_03068 3.82e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GBCLOFCM_03069 1.18e-160 ecsC - - S - - - EcsC protein family
GBCLOFCM_03070 4.47e-261 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GBCLOFCM_03071 1.1e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
GBCLOFCM_03072 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GBCLOFCM_03073 2.06e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GBCLOFCM_03074 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
GBCLOFCM_03075 1.74e-54 yhaH - - S - - - YtxH-like protein
GBCLOFCM_03076 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
GBCLOFCM_03077 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
GBCLOFCM_03078 9.86e-34 yhaK - - S - - - Putative zincin peptidase
GBCLOFCM_03079 6.19e-53 yhaK - - S - - - Putative zincin peptidase
GBCLOFCM_03080 6.57e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GBCLOFCM_03081 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
GBCLOFCM_03082 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
GBCLOFCM_03083 0.0 yhaN - - L - - - AAA domain
GBCLOFCM_03084 1.34e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
GBCLOFCM_03085 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
GBCLOFCM_03086 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03087 1.1e-34 - - - S - - - YhzD-like protein
GBCLOFCM_03088 1.32e-171 yhaR - - I - - - enoyl-CoA hydratase
GBCLOFCM_03090 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GBCLOFCM_03091 2.97e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
GBCLOFCM_03092 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
GBCLOFCM_03093 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
GBCLOFCM_03094 1.58e-262 yhaZ - - L - - - DNA alkylation repair enzyme
GBCLOFCM_03095 6.5e-69 yheA - - S - - - Belongs to the UPF0342 family
GBCLOFCM_03096 2.4e-258 yheB - - S - - - Belongs to the UPF0754 family
GBCLOFCM_03097 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
GBCLOFCM_03098 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
GBCLOFCM_03099 3.23e-49 yheE - - S - - - Family of unknown function (DUF5342)
GBCLOFCM_03100 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GBCLOFCM_03101 9.1e-141 yheG - - GM - - - NAD(P)H-binding
GBCLOFCM_03102 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_03103 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_03104 1.95e-33 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_03105 3.16e-108 nhaX - - T - - - Belongs to the universal stress protein A family
GBCLOFCM_03106 5.12e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GBCLOFCM_03107 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GBCLOFCM_03108 5.24e-196 nodB1 - - G - - - deacetylase
GBCLOFCM_03109 1.98e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GBCLOFCM_03110 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
GBCLOFCM_03111 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
GBCLOFCM_03112 1.05e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GBCLOFCM_03113 3.94e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBCLOFCM_03114 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBCLOFCM_03115 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
GBCLOFCM_03116 3.44e-282 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GBCLOFCM_03117 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
GBCLOFCM_03118 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GBCLOFCM_03119 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GBCLOFCM_03120 1.52e-240 yhdN - - C - - - Aldo keto reductase
GBCLOFCM_03121 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_03122 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
GBCLOFCM_03123 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
GBCLOFCM_03124 2.91e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBCLOFCM_03125 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_03126 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GBCLOFCM_03127 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
GBCLOFCM_03128 1.92e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_03129 1.24e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GBCLOFCM_03130 5.7e-185 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_03131 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GBCLOFCM_03132 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GBCLOFCM_03133 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
GBCLOFCM_03134 7.16e-305 ygxB - - M - - - Conserved TM helix
GBCLOFCM_03135 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
GBCLOFCM_03136 5.63e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GBCLOFCM_03137 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
GBCLOFCM_03138 1.65e-51 yhdB - - S - - - YhdB-like protein
GBCLOFCM_03139 4.67e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
GBCLOFCM_03140 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_03141 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_03142 3.15e-87 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GBCLOFCM_03143 5.02e-308 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GBCLOFCM_03144 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GBCLOFCM_03145 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GBCLOFCM_03146 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GBCLOFCM_03147 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GBCLOFCM_03148 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GBCLOFCM_03149 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GBCLOFCM_03150 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
GBCLOFCM_03151 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
GBCLOFCM_03152 2.47e-88 yhcU - - S - - - Family of unknown function (DUF5365)
GBCLOFCM_03153 2.76e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GBCLOFCM_03154 1.52e-135 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
GBCLOFCM_03155 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GBCLOFCM_03156 1.68e-146 yhcQ - - M - - - Spore coat protein
GBCLOFCM_03157 1.77e-117 yhcP - - - - - - -
GBCLOFCM_03158 1.57e-60 yhcP - - - - - - -
GBCLOFCM_03159 6.46e-103 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GBCLOFCM_03160 1.13e-70 yhcM - - - - - - -
GBCLOFCM_03161 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GBCLOFCM_03162 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
GBCLOFCM_03163 4.52e-179 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GBCLOFCM_03164 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GBCLOFCM_03165 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GBCLOFCM_03166 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03167 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03168 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_03169 1.18e-68 - - - - - - - -
GBCLOFCM_03170 1.61e-58 yhcC - - - - - - -
GBCLOFCM_03171 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
GBCLOFCM_03172 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
GBCLOFCM_03173 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
GBCLOFCM_03174 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
GBCLOFCM_03175 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
GBCLOFCM_03176 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
GBCLOFCM_03177 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GBCLOFCM_03178 9.3e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GBCLOFCM_03179 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
GBCLOFCM_03180 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GBCLOFCM_03181 2.77e-225 yhbB - - S - - - Putative amidase domain
GBCLOFCM_03182 2.95e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GBCLOFCM_03183 1.92e-147 yhzB - - S - - - B3/4 domain
GBCLOFCM_03185 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_03186 2.79e-102 ygaO - - - - - - -
GBCLOFCM_03187 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GBCLOFCM_03189 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
GBCLOFCM_03190 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GBCLOFCM_03191 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
GBCLOFCM_03192 5.52e-190 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GBCLOFCM_03193 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GBCLOFCM_03195 0.0 ygaK - - C - - - Berberine and berberine like
GBCLOFCM_03196 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GBCLOFCM_03197 2.91e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
GBCLOFCM_03198 3.88e-37 - - - - - - - -
GBCLOFCM_03199 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
GBCLOFCM_03215 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_03216 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
GBCLOFCM_03217 5.46e-74 ygzB - - S - - - UPF0295 protein
GBCLOFCM_03218 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GBCLOFCM_03219 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
GBCLOFCM_03220 3.4e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GBCLOFCM_03221 1.87e-238 ygaE - - S - - - Membrane
GBCLOFCM_03222 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
GBCLOFCM_03223 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GBCLOFCM_03224 1.88e-63 ygaB - - S - - - YgaB-like protein
GBCLOFCM_03225 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
GBCLOFCM_03226 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_03227 1.73e-48 yfhS - - - - - - -
GBCLOFCM_03228 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
GBCLOFCM_03229 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
GBCLOFCM_03230 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GBCLOFCM_03231 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GBCLOFCM_03232 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
GBCLOFCM_03233 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
GBCLOFCM_03234 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
GBCLOFCM_03235 2.57e-59 yfhJ - - S - - - WVELL protein
GBCLOFCM_03236 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
GBCLOFCM_03237 2.45e-268 yfhI - - EGP - - - -transporter
GBCLOFCM_03239 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
GBCLOFCM_03240 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
GBCLOFCM_03241 3.79e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
GBCLOFCM_03243 8.86e-35 yfhD - - S - - - YfhD-like protein
GBCLOFCM_03244 1.66e-137 yfhC - - C - - - nitroreductase
GBCLOFCM_03245 4.4e-214 yfhB - - S - - - PhzF family
GBCLOFCM_03246 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03247 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03248 3.15e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GBCLOFCM_03249 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GBCLOFCM_03250 1.27e-104 yfiV - - K - - - transcriptional
GBCLOFCM_03251 0.0 yfiU - - EGP - - - the major facilitator superfamily
GBCLOFCM_03252 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
GBCLOFCM_03253 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GBCLOFCM_03254 1.3e-126 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GBCLOFCM_03255 1.89e-128 padR - - K - - - transcriptional
GBCLOFCM_03256 1.34e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GBCLOFCM_03257 5.32e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GBCLOFCM_03258 3.75e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03259 4.1e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
GBCLOFCM_03260 4.67e-270 baeS - - T - - - Histidine kinase
GBCLOFCM_03262 4.21e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GBCLOFCM_03263 3.34e-83 yfiD3 - - S - - - DoxX
GBCLOFCM_03264 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GBCLOFCM_03265 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
GBCLOFCM_03266 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03267 2.49e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GBCLOFCM_03268 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GBCLOFCM_03269 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
GBCLOFCM_03270 1.39e-240 yfjB - - - - - - -
GBCLOFCM_03271 4.33e-161 yfjC - - - - - - -
GBCLOFCM_03272 5.95e-113 - - - S - - - Family of unknown function (DUF5381)
GBCLOFCM_03273 1.38e-72 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
GBCLOFCM_03274 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
GBCLOFCM_03275 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
GBCLOFCM_03276 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GBCLOFCM_03277 5.7e-263 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GBCLOFCM_03278 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GBCLOFCM_03279 2.75e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GBCLOFCM_03281 6.46e-109 yfjM - - S - - - Psort location Cytoplasmic, score
GBCLOFCM_03282 3.33e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBCLOFCM_03283 4.32e-59 - - - S - - - YfzA-like protein
GBCLOFCM_03284 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBCLOFCM_03285 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GBCLOFCM_03286 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
GBCLOFCM_03287 2.1e-188 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GBCLOFCM_03288 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
GBCLOFCM_03289 3.26e-36 yfjT - - - - - - -
GBCLOFCM_03290 1.76e-283 yfkA - - S - - - YfkB-like domain
GBCLOFCM_03291 1.81e-190 yfkC - - M - - - Mechanosensitive ion channel
GBCLOFCM_03292 3.69e-189 yfkD - - S - - - YfkD-like protein
GBCLOFCM_03293 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
GBCLOFCM_03294 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_03295 2.99e-181 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GBCLOFCM_03296 1.03e-66 yfkI - - S - - - gas vesicle protein
GBCLOFCM_03297 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBCLOFCM_03298 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
GBCLOFCM_03299 2.53e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_03300 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GBCLOFCM_03301 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GBCLOFCM_03302 6.16e-160 frp - - C - - - nitroreductase
GBCLOFCM_03303 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
GBCLOFCM_03304 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GBCLOFCM_03305 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03306 5.09e-33 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GBCLOFCM_03307 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
GBCLOFCM_03308 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
GBCLOFCM_03309 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GBCLOFCM_03310 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GBCLOFCM_03311 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GBCLOFCM_03312 6.04e-65 yflH - - S - - - Protein of unknown function (DUF3243)
GBCLOFCM_03313 6.9e-27 yflI - - - - - - -
GBCLOFCM_03314 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
GBCLOFCM_03315 5.91e-158 yflK - - S - - - protein conserved in bacteria
GBCLOFCM_03316 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GBCLOFCM_03317 1.95e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GBCLOFCM_03318 8.08e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GBCLOFCM_03319 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GBCLOFCM_03321 6.89e-231 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
GBCLOFCM_03322 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GBCLOFCM_03323 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GBCLOFCM_03324 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GBCLOFCM_03325 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
GBCLOFCM_03326 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
GBCLOFCM_03327 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
GBCLOFCM_03328 1.6e-218 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GBCLOFCM_03329 7.2e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03330 5.76e-221 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03331 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GBCLOFCM_03332 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
GBCLOFCM_03333 3.46e-268 - - - G - - - Major Facilitator Superfamily
GBCLOFCM_03334 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
GBCLOFCM_03335 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
GBCLOFCM_03336 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
GBCLOFCM_03337 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GBCLOFCM_03338 2.95e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
GBCLOFCM_03339 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
GBCLOFCM_03340 1.31e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
GBCLOFCM_03341 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GBCLOFCM_03342 1.47e-160 yfmS - - NT - - - chemotaxis protein
GBCLOFCM_03343 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GBCLOFCM_03344 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
GBCLOFCM_03345 2.13e-167 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GBCLOFCM_03346 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_03347 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
GBCLOFCM_03348 1.16e-284 yfnE - - S - - - Glycosyltransferase like family 2
GBCLOFCM_03349 3.28e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
GBCLOFCM_03350 1.2e-237 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
GBCLOFCM_03351 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
GBCLOFCM_03352 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GBCLOFCM_03353 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GBCLOFCM_03354 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
GBCLOFCM_03355 1.2e-263 yetM - - CH - - - FAD binding domain
GBCLOFCM_03356 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_03357 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
GBCLOFCM_03358 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
GBCLOFCM_03359 1.2e-182 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GBCLOFCM_03360 1.75e-44 - - - - - - - -
GBCLOFCM_03361 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GBCLOFCM_03362 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
GBCLOFCM_03363 1.49e-156 yetF - - S - - - membrane
GBCLOFCM_03364 4.53e-266 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GBCLOFCM_03365 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_03366 5.62e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GBCLOFCM_03367 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GBCLOFCM_03368 0.0 yetA - - - - - - -
GBCLOFCM_03369 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
GBCLOFCM_03370 6.17e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
GBCLOFCM_03371 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GBCLOFCM_03372 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GBCLOFCM_03373 3.3e-144 - - - S - - - Protein of unknown function, DUF624
GBCLOFCM_03374 7.52e-165 yesU - - S - - - Domain of unknown function (DUF1961)
GBCLOFCM_03375 5.67e-168 - - - E - - - GDSL-like Lipase/Acylhydrolase
GBCLOFCM_03376 0.0 yesS - - K - - - Transcriptional regulator
GBCLOFCM_03377 6.57e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
GBCLOFCM_03378 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_03379 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GBCLOFCM_03380 1.44e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GBCLOFCM_03381 1.62e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
GBCLOFCM_03382 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_03383 1.04e-131 yesL - - S - - - Protein of unknown function, DUF624
GBCLOFCM_03385 1.02e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
GBCLOFCM_03386 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
GBCLOFCM_03387 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
GBCLOFCM_03388 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
GBCLOFCM_03389 1.23e-195 yesF - - GM - - - NAD(P)H-binding
GBCLOFCM_03390 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
GBCLOFCM_03391 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
GBCLOFCM_03393 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
GBCLOFCM_03395 2.87e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
GBCLOFCM_03396 1.62e-17 - - - S - - - Pfam:DUF1311
GBCLOFCM_03398 3.52e-71 - - - - - - - -
GBCLOFCM_03399 8.09e-221 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
GBCLOFCM_03400 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
GBCLOFCM_03401 1.95e-104 - - - S - - - Protein of unknown function, DUF600
GBCLOFCM_03402 1.33e-47 - - - S - - - Protein of unknown function, DUF600
GBCLOFCM_03403 6.26e-62 - - - S - - - Protein of unknown function (DUF1643)
GBCLOFCM_03404 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type I restriction enzyme R protein N terminus (HSDR_N)
GBCLOFCM_03405 1.76e-125 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GBCLOFCM_03406 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
GBCLOFCM_03407 1.05e-65 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
GBCLOFCM_03409 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBCLOFCM_03410 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GBCLOFCM_03411 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GBCLOFCM_03412 8.4e-201 yerO - - K - - - Transcriptional regulator
GBCLOFCM_03413 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBCLOFCM_03414 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GBCLOFCM_03415 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBCLOFCM_03416 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBCLOFCM_03417 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
GBCLOFCM_03418 1.22e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
GBCLOFCM_03419 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
GBCLOFCM_03420 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBCLOFCM_03421 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GBCLOFCM_03422 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GBCLOFCM_03423 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
GBCLOFCM_03424 7.62e-68 yerC - - S - - - protein conserved in bacteria
GBCLOFCM_03425 2.15e-239 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
GBCLOFCM_03426 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
GBCLOFCM_03427 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
GBCLOFCM_03428 1.08e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
GBCLOFCM_03429 1.06e-95 - - - K - - - helix_turn_helix ASNC type
GBCLOFCM_03430 1.4e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GBCLOFCM_03431 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GBCLOFCM_03432 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GBCLOFCM_03433 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GBCLOFCM_03434 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GBCLOFCM_03435 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBCLOFCM_03436 7.78e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBCLOFCM_03437 1.55e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBCLOFCM_03438 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GBCLOFCM_03439 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBCLOFCM_03440 1.28e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GBCLOFCM_03441 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GBCLOFCM_03442 3.13e-38 yebG - - S - - - NETI protein
GBCLOFCM_03443 2.66e-120 yebE - - S - - - UPF0316 protein
GBCLOFCM_03445 1.68e-164 yebC - - M - - - Membrane
GBCLOFCM_03446 4.65e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GBCLOFCM_03447 3.29e-314 - - - S - - - Domain of unknown function (DUF4179)
GBCLOFCM_03448 6.85e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_03449 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GBCLOFCM_03450 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
GBCLOFCM_03451 4.55e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GBCLOFCM_03452 9.57e-218 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
GBCLOFCM_03453 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBCLOFCM_03454 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_03455 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
GBCLOFCM_03456 2.49e-229 yeaA - - S - - - Protein of unknown function (DUF4003)
GBCLOFCM_03457 3.45e-200 - - - I - - - Alpha/beta hydrolase family
GBCLOFCM_03458 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
GBCLOFCM_03460 3.59e-211 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
GBCLOFCM_03461 1.79e-84 ydjM - - M - - - Lytic transglycolase
GBCLOFCM_03462 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
GBCLOFCM_03463 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GBCLOFCM_03464 3.77e-246 - - - S - - - Ion transport 2 domain protein
GBCLOFCM_03465 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
GBCLOFCM_03466 2.2e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
GBCLOFCM_03467 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBCLOFCM_03468 2.65e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
GBCLOFCM_03469 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
GBCLOFCM_03470 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
GBCLOFCM_03471 5.88e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
GBCLOFCM_03472 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
GBCLOFCM_03473 1.53e-172 ydjC - - S - - - Abhydrolase domain containing 18
GBCLOFCM_03474 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GBCLOFCM_03475 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GBCLOFCM_03476 1.74e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
GBCLOFCM_03477 8.32e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
GBCLOFCM_03478 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBCLOFCM_03479 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GBCLOFCM_03480 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GBCLOFCM_03481 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GBCLOFCM_03482 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
GBCLOFCM_03483 7.76e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GBCLOFCM_03484 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GBCLOFCM_03485 2.4e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
GBCLOFCM_03486 3.02e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
GBCLOFCM_03487 1.05e-228 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GBCLOFCM_03490 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_03493 9.46e-200 ydhU - - P ko:K07217 - ko00000 Catalase
GBCLOFCM_03494 1.17e-271 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GBCLOFCM_03495 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GBCLOFCM_03496 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
GBCLOFCM_03497 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
GBCLOFCM_03498 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GBCLOFCM_03499 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GBCLOFCM_03500 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03501 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03502 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
GBCLOFCM_03503 1.15e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
GBCLOFCM_03504 1.28e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GBCLOFCM_03505 2.11e-107 - - - K - - - Acetyltransferase (GNAT) domain
GBCLOFCM_03507 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
GBCLOFCM_03508 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GBCLOFCM_03509 1.67e-160 - - - - - - - -
GBCLOFCM_03510 2.26e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GBCLOFCM_03511 3.2e-292 ydhD - - M - - - Glycosyl hydrolase
GBCLOFCM_03512 4.31e-157 ydhC - - K - - - FCD
GBCLOFCM_03513 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
GBCLOFCM_03514 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
GBCLOFCM_03515 3.29e-90 - - - K - - - Winged helix DNA-binding domain
GBCLOFCM_03516 1.84e-146 ydgI - - C - - - nitroreductase
GBCLOFCM_03517 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
GBCLOFCM_03518 2.1e-168 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
GBCLOFCM_03519 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_03520 4.18e-118 - - - S - - - DinB family
GBCLOFCM_03521 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_03522 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
GBCLOFCM_03523 4.66e-110 yycN - - K - - - Acetyltransferase
GBCLOFCM_03524 6.73e-69 - - - S - - - DoxX-like family
GBCLOFCM_03525 5.75e-128 ydgC - - K - - - Bacterial regulatory proteins, tetR family
GBCLOFCM_03526 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
GBCLOFCM_03527 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
GBCLOFCM_03528 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GBCLOFCM_03529 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
GBCLOFCM_03530 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
GBCLOFCM_03532 5.33e-39 - - - - - - - -
GBCLOFCM_03533 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
GBCLOFCM_03534 9.27e-75 ydfQ - - CO - - - Thioredoxin
GBCLOFCM_03535 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
GBCLOFCM_03536 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GBCLOFCM_03537 2.72e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
GBCLOFCM_03538 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBCLOFCM_03539 1.61e-184 - - - K - - - Bacterial transcription activator, effector binding domain
GBCLOFCM_03540 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GBCLOFCM_03541 6.57e-224 - - - S - - - Alpha/beta hydrolase family
GBCLOFCM_03542 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
GBCLOFCM_03543 3.82e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBCLOFCM_03544 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_03546 1.6e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBCLOFCM_03547 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GBCLOFCM_03548 6.97e-150 ydfE - - S - - - Flavin reductase like domain
GBCLOFCM_03549 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_03550 1.81e-199 - - - EG - - - EamA-like transporter family
GBCLOFCM_03551 2.59e-187 - - - J - - - GNAT acetyltransferase
GBCLOFCM_03552 1.06e-295 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GBCLOFCM_03553 2.11e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
GBCLOFCM_03554 1.46e-133 ydeS - - K - - - Transcriptional regulator
GBCLOFCM_03555 9.29e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
GBCLOFCM_03556 6.98e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
GBCLOFCM_03557 5.03e-91 ydeP - - K - - - Transcriptional regulator
GBCLOFCM_03558 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GBCLOFCM_03559 2.91e-72 - - - K - - - HxlR-like helix-turn-helix
GBCLOFCM_03560 1.43e-136 - - - S ko:K07002 - ko00000 Serine hydrolase
GBCLOFCM_03561 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
GBCLOFCM_03562 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_03563 4.66e-197 ydeK - - EG - - - -transporter
GBCLOFCM_03564 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
GBCLOFCM_03565 1.64e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
GBCLOFCM_03566 1.1e-39 - - - S - - - SNARE associated Golgi protein
GBCLOFCM_03567 3.16e-121 - - - - - - - -
GBCLOFCM_03568 5.52e-133 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
GBCLOFCM_03569 7.55e-69 ydeH - - - - - - -
GBCLOFCM_03570 1.54e-276 ydeG - - EGP - - - Major facilitator superfamily
GBCLOFCM_03571 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_03572 9.98e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
GBCLOFCM_03573 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GBCLOFCM_03574 2.18e-213 - - - K - - - AraC-like ligand binding domain
GBCLOFCM_03575 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GBCLOFCM_03576 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
GBCLOFCM_03577 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
GBCLOFCM_03578 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
GBCLOFCM_03582 6e-53 - - - - - - - -
GBCLOFCM_03583 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GBCLOFCM_03586 7.24e-08 - - - S - - - Putative amidase domain
GBCLOFCM_03589 9.05e-56 - - - L - - - HNH nucleases
GBCLOFCM_03590 3.79e-06 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
GBCLOFCM_03591 2.85e-58 - - - - - - - -
GBCLOFCM_03592 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
GBCLOFCM_03600 2.17e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GBCLOFCM_03601 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
GBCLOFCM_03602 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
GBCLOFCM_03603 6.29e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GBCLOFCM_03604 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GBCLOFCM_03605 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
GBCLOFCM_03606 1.86e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
GBCLOFCM_03607 1.31e-80 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GBCLOFCM_03608 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
GBCLOFCM_03609 2.46e-183 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
GBCLOFCM_03610 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GBCLOFCM_03611 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GBCLOFCM_03612 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBCLOFCM_03613 1.56e-232 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
GBCLOFCM_03614 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GBCLOFCM_03615 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
GBCLOFCM_03616 1.33e-32 ydbT - - S ko:K08981 - ko00000 Membrane
GBCLOFCM_03617 4.85e-99 ydbT - - S ko:K08981 - ko00000 Membrane
GBCLOFCM_03618 7.92e-27 ydbT - - S ko:K08981 - ko00000 Membrane
GBCLOFCM_03619 7.15e-59 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
GBCLOFCM_03620 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GBCLOFCM_03621 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GBCLOFCM_03622 8.43e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GBCLOFCM_03623 4.19e-75 ydbP - - CO - - - Thioredoxin
GBCLOFCM_03624 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBCLOFCM_03625 2.1e-11 - - - S - - - Fur-regulated basic protein A
GBCLOFCM_03626 1.49e-26 - - - S - - - Fur-regulated basic protein B
GBCLOFCM_03627 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
GBCLOFCM_03628 9.32e-70 ydbL - - - - - - -
GBCLOFCM_03629 4.25e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GBCLOFCM_03630 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03631 1.32e-230 ydbI - - S - - - AI-2E family transporter
GBCLOFCM_03632 2.34e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GBCLOFCM_03633 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GBCLOFCM_03634 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GBCLOFCM_03635 1.49e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GBCLOFCM_03636 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
GBCLOFCM_03637 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
GBCLOFCM_03638 3.09e-78 ydbB - - G - - - Cupin domain
GBCLOFCM_03639 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
GBCLOFCM_03640 5.53e-177 ydbA - - P - - - EcsC protein family
GBCLOFCM_03641 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GBCLOFCM_03642 1.67e-42 ydaS - - S - - - membrane
GBCLOFCM_03643 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GBCLOFCM_03644 2.5e-52 - - - - - - - -
GBCLOFCM_03645 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GBCLOFCM_03646 2.28e-86 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GBCLOFCM_03647 0.0 ydaO - - E - - - amino acid
GBCLOFCM_03648 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
GBCLOFCM_03649 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
GBCLOFCM_03650 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
GBCLOFCM_03651 1.56e-193 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
GBCLOFCM_03652 5.97e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
GBCLOFCM_03653 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBCLOFCM_03654 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GBCLOFCM_03655 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
GBCLOFCM_03656 7.59e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GBCLOFCM_03657 1.5e-100 ydaG - - S - - - general stress protein
GBCLOFCM_03658 2.58e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBCLOFCM_03659 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
GBCLOFCM_03660 6.21e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_03661 7.07e-128 ydaC - - Q - - - Methyltransferase domain
GBCLOFCM_03662 0.0 ydaB - - IQ - - - acyl-CoA ligase
GBCLOFCM_03663 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
GBCLOFCM_03664 5.18e-221 ycsN - - S - - - Oxidoreductase
GBCLOFCM_03665 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
GBCLOFCM_03666 7.67e-66 yczJ - - S - - - biosynthesis
GBCLOFCM_03668 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
GBCLOFCM_03669 3.8e-171 kipR - - K - - - Transcriptional regulator
GBCLOFCM_03670 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
GBCLOFCM_03671 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
GBCLOFCM_03672 6.72e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
GBCLOFCM_03673 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
GBCLOFCM_03674 1.56e-166 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
GBCLOFCM_03675 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GBCLOFCM_03677 9.34e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
GBCLOFCM_03678 4.59e-114 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
GBCLOFCM_03679 3.35e-88 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GBCLOFCM_03681 1.46e-197 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
GBCLOFCM_03682 8.13e-15 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
GBCLOFCM_03683 8.5e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
GBCLOFCM_03684 3.88e-78 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GBCLOFCM_03685 2.52e-282 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
GBCLOFCM_03686 1.34e-74 - - - - - - - -
GBCLOFCM_03687 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GBCLOFCM_03688 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
GBCLOFCM_03689 3.99e-134 ycnI - - S - - - protein conserved in bacteria
GBCLOFCM_03690 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GBCLOFCM_03691 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
GBCLOFCM_03692 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GBCLOFCM_03693 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GBCLOFCM_03694 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBCLOFCM_03695 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GBCLOFCM_03696 1.68e-60 ycnE - - S - - - Monooxygenase
GBCLOFCM_03697 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GBCLOFCM_03698 1.75e-195 ycnC - - K - - - Transcriptional regulator
GBCLOFCM_03699 0.0 ycnB - - EGP - - - the major facilitator superfamily
GBCLOFCM_03700 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
GBCLOFCM_03701 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03702 7.77e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03703 1.87e-200 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03704 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GBCLOFCM_03705 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GBCLOFCM_03706 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GBCLOFCM_03708 8.75e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GBCLOFCM_03709 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GBCLOFCM_03710 6.39e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_03711 2.27e-279 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
GBCLOFCM_03712 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GBCLOFCM_03713 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
GBCLOFCM_03714 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
GBCLOFCM_03715 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GBCLOFCM_03717 0.0 yclG - - M - - - Pectate lyase superfamily protein
GBCLOFCM_03718 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
GBCLOFCM_03719 1.92e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
GBCLOFCM_03720 3.39e-105 yclD - - - - - - -
GBCLOFCM_03721 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GBCLOFCM_03722 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GBCLOFCM_03723 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
GBCLOFCM_03724 7.14e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GBCLOFCM_03725 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GBCLOFCM_03726 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GBCLOFCM_03727 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
GBCLOFCM_03728 2.9e-96 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
GBCLOFCM_03729 9.36e-317 ycxD - - K - - - GntR family transcriptional regulator
GBCLOFCM_03730 3.98e-206 ycxC - - EG - - - EamA-like transporter family
GBCLOFCM_03731 2.99e-122 - - - S - - - YcxB-like protein
GBCLOFCM_03732 1.51e-231 - - - EGP - - - Major Facilitator Superfamily
GBCLOFCM_03733 1.91e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
GBCLOFCM_03734 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
GBCLOFCM_03735 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_03736 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_03737 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBCLOFCM_03738 6.05e-86 hxlR - - K - - - transcriptional
GBCLOFCM_03739 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
GBCLOFCM_03740 6.55e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
GBCLOFCM_03741 1.76e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GBCLOFCM_03742 1.48e-51 nucA - - M - - - Deoxyribonuclease NucA/NucB
GBCLOFCM_03743 4.78e-91 nin - - S - - - Competence protein J (ComJ)
GBCLOFCM_03744 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GBCLOFCM_03745 1.04e-123 - - - S - - - AAA domain
GBCLOFCM_03746 4.68e-06 cysA1 - - S - - - AAA domain
GBCLOFCM_03747 4.57e-18 - - - - - - - -
GBCLOFCM_03748 1.29e-58 - - - K - - - MarR family
GBCLOFCM_03749 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
GBCLOFCM_03750 5.34e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBCLOFCM_03751 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GBCLOFCM_03752 6.5e-289 yciC - - S - - - GTPases (G3E family)
GBCLOFCM_03753 1.04e-140 - - - M - - - ErfK YbiS YcfS YnhG
GBCLOFCM_03754 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
GBCLOFCM_03755 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GBCLOFCM_03756 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
GBCLOFCM_03757 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GBCLOFCM_03758 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBCLOFCM_03759 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
GBCLOFCM_03760 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GBCLOFCM_03761 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GBCLOFCM_03762 9.86e-202 ycgS - - I - - - alpha/beta hydrolase fold
GBCLOFCM_03763 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
GBCLOFCM_03764 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
GBCLOFCM_03765 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
GBCLOFCM_03766 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBCLOFCM_03767 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GBCLOFCM_03768 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GBCLOFCM_03769 2.6e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
GBCLOFCM_03770 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
GBCLOFCM_03771 9.34e-227 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
GBCLOFCM_03772 2.06e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
GBCLOFCM_03773 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GBCLOFCM_03774 1.79e-138 tmrB - - S - - - AAA domain
GBCLOFCM_03775 7.44e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GBCLOFCM_03776 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
GBCLOFCM_03777 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_03778 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
GBCLOFCM_03779 2.61e-146 ycgF - - E - - - Lysine exporter protein LysE YggA
GBCLOFCM_03780 3.04e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
GBCLOFCM_03781 0.0 mdr - - EGP - - - the major facilitator superfamily
GBCLOFCM_03782 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GBCLOFCM_03783 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GBCLOFCM_03784 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
GBCLOFCM_03785 6.5e-125 ycgB - - - - - - -
GBCLOFCM_03786 0.0 ycgA - - S - - - Membrane
GBCLOFCM_03787 9.75e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
GBCLOFCM_03788 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GBCLOFCM_03789 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GBCLOFCM_03790 9.62e-113 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
GBCLOFCM_03791 7.86e-152 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
GBCLOFCM_03792 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GBCLOFCM_03793 3.06e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
GBCLOFCM_03794 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
GBCLOFCM_03795 5.72e-243 yceH - - P - - - Belongs to the TelA family
GBCLOFCM_03796 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
GBCLOFCM_03797 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
GBCLOFCM_03798 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GBCLOFCM_03799 1.57e-100 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GBCLOFCM_03800 3.08e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
GBCLOFCM_03801 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBCLOFCM_03802 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GBCLOFCM_03803 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GBCLOFCM_03804 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GBCLOFCM_03805 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GBCLOFCM_03806 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
GBCLOFCM_03807 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
GBCLOFCM_03808 2.09e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GBCLOFCM_03809 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_03810 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_03811 1.58e-240 ycdA - - S - - - Domain of unknown function (DUF5105)
GBCLOFCM_03812 5.59e-221 yccK - - C - - - Aldo keto reductase
GBCLOFCM_03813 1.55e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GBCLOFCM_03814 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GBCLOFCM_03815 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GBCLOFCM_03816 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GBCLOFCM_03817 6.84e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
GBCLOFCM_03818 4.65e-73 - - - S - - - RDD family
GBCLOFCM_03819 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GBCLOFCM_03820 7.18e-259 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GBCLOFCM_03821 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GBCLOFCM_03822 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
GBCLOFCM_03823 2.22e-257 ycbU - - E - - - Selenocysteine lyase
GBCLOFCM_03824 1.2e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GBCLOFCM_03825 1.51e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBCLOFCM_03826 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GBCLOFCM_03827 6.66e-214 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
GBCLOFCM_03828 6.92e-156 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
GBCLOFCM_03829 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
GBCLOFCM_03830 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
GBCLOFCM_03831 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
GBCLOFCM_03832 4.07e-148 - - - S - - - ABC-2 family transporter protein
GBCLOFCM_03833 3.91e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GBCLOFCM_03834 6.48e-216 ycbM - - T - - - Histidine kinase
GBCLOFCM_03835 3.18e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBCLOFCM_03836 3.07e-214 eamA1 - - EG - - - spore germination
GBCLOFCM_03837 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
GBCLOFCM_03838 5.2e-224 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
GBCLOFCM_03839 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GBCLOFCM_03840 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
GBCLOFCM_03841 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GBCLOFCM_03842 3.65e-316 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_03843 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GBCLOFCM_03844 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
GBCLOFCM_03845 1.42e-215 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
GBCLOFCM_03846 5.67e-136 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_03847 5.49e-127 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GBCLOFCM_03848 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GBCLOFCM_03849 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GBCLOFCM_03851 1.51e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
GBCLOFCM_03852 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GBCLOFCM_03853 9.43e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GBCLOFCM_03855 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GBCLOFCM_03856 2.12e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GBCLOFCM_03857 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03858 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GBCLOFCM_03859 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
GBCLOFCM_03860 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
GBCLOFCM_03861 1.58e-59 ybfN - - - - - - -
GBCLOFCM_03862 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GBCLOFCM_03863 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
GBCLOFCM_03864 5.67e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBCLOFCM_03865 3.91e-214 - - - S - - - Alpha/beta hydrolase family
GBCLOFCM_03867 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
GBCLOFCM_03868 8.89e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GBCLOFCM_03869 3.2e-89 - - - M - - - nucleic acid phosphodiester bond hydrolysis
GBCLOFCM_03870 1.15e-186 draG - - O - - - ADP-ribosylglycohydrolase
GBCLOFCM_03871 3.6e-154 ybfI - - K - - - AraC-like ligand binding domain
GBCLOFCM_03872 5.27e-208 ybfH - - EG - - - EamA-like transporter family
GBCLOFCM_03873 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
GBCLOFCM_03875 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
GBCLOFCM_03876 2.1e-218 ybfA - - K - - - FR47-like protein
GBCLOFCM_03877 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
GBCLOFCM_03878 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
GBCLOFCM_03879 5.76e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
GBCLOFCM_03880 0.0 ybeC - - E - - - amino acid
GBCLOFCM_03881 1.11e-54 ybyB - - - - - - -
GBCLOFCM_03882 2.67e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
GBCLOFCM_03883 4.33e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
GBCLOFCM_03884 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
GBCLOFCM_03885 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
GBCLOFCM_03886 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GBCLOFCM_03887 7.37e-273 ybdO - - S - - - Domain of unknown function (DUF4885)
GBCLOFCM_03888 3.67e-193 ybdN - - - - - - -
GBCLOFCM_03889 1.18e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
GBCLOFCM_03891 1.38e-219 - - - T - - - His Kinase A (phospho-acceptor) domain
GBCLOFCM_03892 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
GBCLOFCM_03893 3.83e-231 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBCLOFCM_03894 5.88e-103 - - - CO - - - Thioredoxin-like domain
GBCLOFCM_03895 3.88e-118 - - - C - - - HEAT repeats
GBCLOFCM_03896 3.99e-313 skfF - - S - - - ABC transporter
GBCLOFCM_03897 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GBCLOFCM_03898 5.4e-214 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GBCLOFCM_03899 3.96e-122 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
GBCLOFCM_03900 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
GBCLOFCM_03902 6.59e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
GBCLOFCM_03903 9.45e-67 - - - K - - - Helix-turn-helix domain
GBCLOFCM_03904 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
GBCLOFCM_03905 4.6e-63 - - - - - - - -
GBCLOFCM_03907 1.34e-118 ybcF - - P - - - carbonic anhydrase
GBCLOFCM_03908 7.79e-159 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
GBCLOFCM_03909 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
GBCLOFCM_03910 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GBCLOFCM_03911 3.69e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBCLOFCM_03912 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
GBCLOFCM_03913 2.67e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GBCLOFCM_03914 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GBCLOFCM_03915 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBCLOFCM_03916 1.44e-290 ybbR - - S - - - protein conserved in bacteria
GBCLOFCM_03917 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GBCLOFCM_03918 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GBCLOFCM_03919 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GBCLOFCM_03925 3.12e-81 ybbK - - S - - - Protein of unknown function (DUF523)
GBCLOFCM_03926 1.24e-69 ybbJ - - J - - - acetyltransferase
GBCLOFCM_03927 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GBCLOFCM_03928 5.43e-194 ybbH - - K - - - transcriptional
GBCLOFCM_03929 5.99e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GBCLOFCM_03930 8e-310 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
GBCLOFCM_03931 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
GBCLOFCM_03932 8.14e-303 ybbC - - S - - - protein conserved in bacteria
GBCLOFCM_03933 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
GBCLOFCM_03934 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
GBCLOFCM_03935 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03936 1.1e-207 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBCLOFCM_03937 3.18e-150 ybbA - - S ko:K07017 - ko00000 Putative esterase
GBCLOFCM_03938 2.34e-203 ybaS - - S - - - Na -dependent transporter
GBCLOFCM_03939 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GBCLOFCM_03940 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_03941 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_03948 3.44e-52 - - - S - - - COG NOG15344 non supervised orthologous group
GBCLOFCM_03949 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_03950 1.23e-180 pdaB - - G - - - Polysaccharide deacetylase
GBCLOFCM_03951 1.1e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
GBCLOFCM_03952 1.04e-122 gerD - - - ko:K06294 - ko00000 -
GBCLOFCM_03953 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GBCLOFCM_03954 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GBCLOFCM_03955 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
GBCLOFCM_03956 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
GBCLOFCM_03957 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GBCLOFCM_03958 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBCLOFCM_03959 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GBCLOFCM_03960 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBCLOFCM_03961 3.67e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBCLOFCM_03962 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBCLOFCM_03963 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GBCLOFCM_03964 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBCLOFCM_03965 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GBCLOFCM_03966 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBCLOFCM_03967 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GBCLOFCM_03968 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GBCLOFCM_03969 4.68e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GBCLOFCM_03970 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GBCLOFCM_03971 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GBCLOFCM_03972 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GBCLOFCM_03973 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GBCLOFCM_03974 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GBCLOFCM_03975 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GBCLOFCM_03976 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GBCLOFCM_03977 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GBCLOFCM_03978 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GBCLOFCM_03979 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GBCLOFCM_03980 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GBCLOFCM_03981 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GBCLOFCM_03982 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GBCLOFCM_03983 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GBCLOFCM_03984 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GBCLOFCM_03985 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GBCLOFCM_03986 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GBCLOFCM_03987 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GBCLOFCM_03988 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GBCLOFCM_03989 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GBCLOFCM_03990 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GBCLOFCM_03991 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GBCLOFCM_03992 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GBCLOFCM_03993 1.29e-230 ybaC - - S - - - Alpha/beta hydrolase family
GBCLOFCM_03994 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GBCLOFCM_03995 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GBCLOFCM_03996 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GBCLOFCM_03997 1.93e-90 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GBCLOFCM_03998 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
GBCLOFCM_03999 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBCLOFCM_04000 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBCLOFCM_04001 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GBCLOFCM_04002 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GBCLOFCM_04003 1.82e-99 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GBCLOFCM_04004 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GBCLOFCM_04005 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBCLOFCM_04006 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GBCLOFCM_04007 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GBCLOFCM_04008 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GBCLOFCM_04009 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
GBCLOFCM_04010 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBCLOFCM_04011 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GBCLOFCM_04012 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GBCLOFCM_04013 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
GBCLOFCM_04014 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBCLOFCM_04015 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GBCLOFCM_04016 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GBCLOFCM_04017 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
GBCLOFCM_04018 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GBCLOFCM_04019 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GBCLOFCM_04020 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
GBCLOFCM_04021 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GBCLOFCM_04022 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
GBCLOFCM_04023 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GBCLOFCM_04024 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_04034 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_04035 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GBCLOFCM_04036 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBCLOFCM_04037 1.81e-41 yazB - - K - - - transcriptional
GBCLOFCM_04038 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GBCLOFCM_04039 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GBCLOFCM_04040 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GBCLOFCM_04041 4.4e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
GBCLOFCM_04042 3.46e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
GBCLOFCM_04043 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBCLOFCM_04044 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GBCLOFCM_04045 1.7e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
GBCLOFCM_04046 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GBCLOFCM_04047 1.67e-153 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GBCLOFCM_04048 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBCLOFCM_04049 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
GBCLOFCM_04050 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GBCLOFCM_04051 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
GBCLOFCM_04052 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GBCLOFCM_04053 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
GBCLOFCM_04056 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GBCLOFCM_04057 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GBCLOFCM_04058 4.28e-137 yabQ - - S - - - spore cortex biosynthesis protein
GBCLOFCM_04059 1.91e-66 yabP - - S - - - Sporulation protein YabP
GBCLOFCM_04060 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GBCLOFCM_04061 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GBCLOFCM_04062 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GBCLOFCM_04063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
GBCLOFCM_04064 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GBCLOFCM_04065 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
GBCLOFCM_04066 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GBCLOFCM_04067 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GBCLOFCM_04068 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBCLOFCM_04069 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GBCLOFCM_04070 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GBCLOFCM_04071 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
GBCLOFCM_04072 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GBCLOFCM_04073 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GBCLOFCM_04074 1.28e-35 sspF - - S ko:K06423 - ko00000 DNA topological change
GBCLOFCM_04075 5.32e-53 veg - - S - - - protein conserved in bacteria
GBCLOFCM_04076 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
GBCLOFCM_04077 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GBCLOFCM_04078 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GBCLOFCM_04079 1.91e-283 yabE - - T - - - protein conserved in bacteria
GBCLOFCM_04080 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
GBCLOFCM_04081 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBCLOFCM_04082 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
GBCLOFCM_04083 1.03e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GBCLOFCM_04084 8.46e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
GBCLOFCM_04085 8.05e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
GBCLOFCM_04086 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
GBCLOFCM_04087 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
GBCLOFCM_04088 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GBCLOFCM_04089 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
GBCLOFCM_04090 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
GBCLOFCM_04091 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GBCLOFCM_04092 3.78e-115 yaaO - - E - - - Orn Lys Arg decarboxylase
GBCLOFCM_04093 1.21e-151 yaaO - - E - - - Orn Lys Arg decarboxylase
GBCLOFCM_04094 6.87e-258 yaaN - - P - - - Belongs to the TelA family
GBCLOFCM_04095 2.7e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GBCLOFCM_04096 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
GBCLOFCM_04099 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_04100 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
GBCLOFCM_04101 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
GBCLOFCM_04102 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GBCLOFCM_04103 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBCLOFCM_04104 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBCLOFCM_04105 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GBCLOFCM_04106 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
GBCLOFCM_04107 4.45e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
GBCLOFCM_04108 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
GBCLOFCM_04109 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
GBCLOFCM_04111 3.98e-295 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBCLOFCM_04112 6.75e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GBCLOFCM_04113 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GBCLOFCM_04114 2.16e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GBCLOFCM_04115 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GBCLOFCM_04116 2.14e-232 yaaC - - S - - - YaaC-like Protein
GBCLOFCM_04119 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GBCLOFCM_04120 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBCLOFCM_04121 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBCLOFCM_04122 1.58e-26 yaaB - - S - - - Domain of unknown function (DUF370)
GBCLOFCM_04123 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBCLOFCM_04124 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
GBCLOFCM_04125 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GBCLOFCM_04126 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)