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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HMKIHHLC_00001	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HMKIHHLC_00002	3.17e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMKIHHLC_00003	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMKIHHLC_00004	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HMKIHHLC_00005	4.41e-156	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
HMKIHHLC_00006	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMKIHHLC_00007	2.08e-137	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMKIHHLC_00008	7.86e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMKIHHLC_00009	2.82e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMKIHHLC_00010	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMKIHHLC_00011	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HMKIHHLC_00012	1.66e-218	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HMKIHHLC_00014	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMKIHHLC_00015	2.67e-136	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HMKIHHLC_00016	5.76e-61	-	-	-	-	-	-	-	-
HMKIHHLC_00017	8.39e-168	-	-	-	S	-	-	-	SseB protein N-terminal domain
HMKIHHLC_00018	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMKIHHLC_00019	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HMKIHHLC_00020	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMKIHHLC_00021	6.51e-85	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HMKIHHLC_00022	5.85e-141	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HMKIHHLC_00023	1.19e-69	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HMKIHHLC_00024	2.14e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
HMKIHHLC_00025	1.93e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMKIHHLC_00026	1.37e-220	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMKIHHLC_00027	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HMKIHHLC_00028	3.02e-262	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HMKIHHLC_00029	3.95e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HMKIHHLC_00030	5.06e-168	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMKIHHLC_00031	3.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HMKIHHLC_00032	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMKIHHLC_00033	2.06e-179	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HMKIHHLC_00034	1.67e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HMKIHHLC_00035	3.82e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMKIHHLC_00036	1.71e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMKIHHLC_00037	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMKIHHLC_00038	1.01e-157	csrR	-	-	K	-	-	-	response regulator
HMKIHHLC_00039	5.29e-296	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_00040	8.99e-229	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMKIHHLC_00041	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HMKIHHLC_00042	1.82e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMKIHHLC_00043	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMKIHHLC_00044	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMKIHHLC_00045	5.64e-278	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMKIHHLC_00047	8.49e-242	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HMKIHHLC_00048	1.68e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_00049	8.41e-202	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HMKIHHLC_00051	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_00052	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_00053	4.51e-41	-	-	-	-	-	-	-	-
HMKIHHLC_00054	4.93e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMKIHHLC_00055	1.33e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HMKIHHLC_00056	5.96e-53	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMKIHHLC_00057	8.12e-69	-	-	-	-	-	-	-	-
HMKIHHLC_00058	2.49e-105	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HMKIHHLC_00059	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HMKIHHLC_00060	4.49e-185	-	-	-	S	-	-	-	AAA ATPase domain
HMKIHHLC_00061	9.24e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HMKIHHLC_00062	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_00063	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_00064	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_00065	3.82e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMKIHHLC_00066	3.68e-136	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
HMKIHHLC_00067	4.34e-54	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HMKIHHLC_00068	6.17e-109	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HMKIHHLC_00069	4.64e-152	-	-	-	S	-	-	-	Protein of unknown function DUF58
HMKIHHLC_00070	7.36e-66	-	-	-	S	-	-	-	Protein of unknown function DUF58
HMKIHHLC_00071	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HMKIHHLC_00072	3.5e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMKIHHLC_00073	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMKIHHLC_00074	9.05e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HMKIHHLC_00075	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HMKIHHLC_00076	2.03e-147	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HMKIHHLC_00077	1.49e-61	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HMKIHHLC_00078	7.36e-272	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HMKIHHLC_00079	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
HMKIHHLC_00080	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMKIHHLC_00081	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMKIHHLC_00082	1.28e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
HMKIHHLC_00084	7.77e-259	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HMKIHHLC_00085	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMKIHHLC_00086	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_00087	2.05e-195	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMKIHHLC_00088	5.23e-204	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HMKIHHLC_00089	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HMKIHHLC_00090	9.06e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMKIHHLC_00091	2.91e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMKIHHLC_00092	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HMKIHHLC_00093	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
HMKIHHLC_00094	5.23e-50	-	-	-	-	-	-	-	-
HMKIHHLC_00095	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HMKIHHLC_00096	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMKIHHLC_00097	9.99e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMKIHHLC_00098	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HMKIHHLC_00099	1.43e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMKIHHLC_00100	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMKIHHLC_00101	6.38e-148	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HMKIHHLC_00102	1.58e-213	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HMKIHHLC_00103	2.43e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_00104	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMKIHHLC_00106	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HMKIHHLC_00107	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMKIHHLC_00108	2.35e-213	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HMKIHHLC_00109	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_00111	6e-148	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_00112	1.02e-144	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_00113	3.07e-116	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HMKIHHLC_00114	4.7e-144	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMKIHHLC_00115	3.6e-164	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMKIHHLC_00116	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_00117	7.71e-276	-	-	-	-	-	-	-	-
HMKIHHLC_00118	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMKIHHLC_00119	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMKIHHLC_00120	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HMKIHHLC_00121	4.67e-24	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HMKIHHLC_00123	4.57e-123	-	-	-	S	-	-	-	Phospholipase A2
HMKIHHLC_00124	9.97e-188	-	-	-	EG	-	-	-	EamA-like transporter family
HMKIHHLC_00125	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
HMKIHHLC_00126	8.13e-82	-	-	-	-	-	-	-	-
HMKIHHLC_00127	6.84e-130	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMKIHHLC_00128	9.72e-90	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMKIHHLC_00129	9.48e-237	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMKIHHLC_00130	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HMKIHHLC_00131	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMKIHHLC_00132	4.4e-116	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMKIHHLC_00133	6.4e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMKIHHLC_00134	6.02e-216	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMKIHHLC_00135	9.01e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMKIHHLC_00137	1.46e-76	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMKIHHLC_00139	1.09e-66	-	-	-	-	-	-	-	-
HMKIHHLC_00140	3.68e-89	-	-	-	-	-	-	-	-
HMKIHHLC_00141	2e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_00142	1.81e-54	-	-	-	-	-	-	-	-
HMKIHHLC_00143	4.66e-100	-	-	-	S	-	-	-	NUDIX domain
HMKIHHLC_00144	1.89e-205	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
HMKIHHLC_00145	1.94e-284	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_00146	8.83e-142	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HMKIHHLC_00147	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
HMKIHHLC_00148	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HMKIHHLC_00149	6.18e-150	-	-	-	-	-	-	-	-
HMKIHHLC_00150	5.14e-288	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HMKIHHLC_00151	2.06e-176	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HMKIHHLC_00152	5.3e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HMKIHHLC_00153	1.47e-07	-	-	-	-	-	-	-	-
HMKIHHLC_00154	5.12e-117	-	-	-	-	-	-	-	-
HMKIHHLC_00155	4.85e-65	-	-	-	-	-	-	-	-
HMKIHHLC_00156	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
HMKIHHLC_00157	2.26e-49	-	-	-	-	-	-	-	-
HMKIHHLC_00158	2.82e-36	-	-	-	-	-	-	-	-
HMKIHHLC_00159	1.66e-218	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKIHHLC_00160	4.58e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HMKIHHLC_00161	4.95e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
HMKIHHLC_00162	2.35e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
HMKIHHLC_00163	4.15e-34	-	-	-	-	-	-	-	-
HMKIHHLC_00164	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMKIHHLC_00165	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMKIHHLC_00166	6.26e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HMKIHHLC_00167	2.37e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HMKIHHLC_00168	9.1e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HMKIHHLC_00169	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMKIHHLC_00170	6.15e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMKIHHLC_00171	1.35e-164	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HMKIHHLC_00172	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMKIHHLC_00173	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HMKIHHLC_00174	1.64e-301	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HMKIHHLC_00175	2.93e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HMKIHHLC_00176	1.72e-265	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HMKIHHLC_00177	1.24e-24	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HMKIHHLC_00178	4.56e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMKIHHLC_00179	1.74e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HMKIHHLC_00180	3.46e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMKIHHLC_00181	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HMKIHHLC_00182	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMKIHHLC_00183	2.38e-310	ymfH	-	-	S	-	-	-	Peptidase M16
HMKIHHLC_00184	2.21e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HMKIHHLC_00185	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMKIHHLC_00186	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HMKIHHLC_00187	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMKIHHLC_00188	8.1e-199	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HMKIHHLC_00189	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMKIHHLC_00190	7.02e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMKIHHLC_00191	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMKIHHLC_00192	4.71e-81	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HMKIHHLC_00193	1.33e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HMKIHHLC_00194	1.09e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMKIHHLC_00195	2.24e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HMKIHHLC_00196	2.34e-61	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
HMKIHHLC_00197	4.8e-104	-	-	-	S	-	-	-	Pfam Transposase IS66
HMKIHHLC_00198	8.05e-196	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HMKIHHLC_00200	1.18e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HMKIHHLC_00201	5.22e-63	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HMKIHHLC_00202	6.02e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HMKIHHLC_00203	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HMKIHHLC_00204	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HMKIHHLC_00205	2.63e-142	vanZ	-	-	V	-	-	-	VanZ like family
HMKIHHLC_00206	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMKIHHLC_00207	6.04e-137	-	-	-	-	-	-	-	-
HMKIHHLC_00208	7.65e-136	-	-	-	-	-	-	-	-
HMKIHHLC_00209	9.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMKIHHLC_00210	1.15e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMKIHHLC_00211	8.85e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HMKIHHLC_00212	2.18e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMKIHHLC_00213	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HMKIHHLC_00214	1.38e-108	yvbK	-	-	K	-	-	-	GNAT family
HMKIHHLC_00215	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HMKIHHLC_00216	8.49e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HMKIHHLC_00217	5.17e-134	-	-	-	-	-	-	-	-
HMKIHHLC_00218	5.71e-173	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HMKIHHLC_00219	1.01e-34	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HMKIHHLC_00220	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMKIHHLC_00221	6.16e-285	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HMKIHHLC_00222	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
HMKIHHLC_00223	9.44e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HMKIHHLC_00224	1.35e-186	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
HMKIHHLC_00225	3.5e-249	pbpE	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_00227	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_00228	5.36e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HMKIHHLC_00229	2.77e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMKIHHLC_00230	2.07e-140	ydfF	-	-	K	-	-	-	Transcriptional
HMKIHHLC_00231	4.02e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HMKIHHLC_00232	1.3e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
HMKIHHLC_00233	0.0	-	-	-	L	-	-	-	Exonuclease
HMKIHHLC_00234	1.05e-101	-	-	-	O	-	-	-	OsmC-like protein
HMKIHHLC_00235	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HMKIHHLC_00236	4.95e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HMKIHHLC_00237	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00238	2.11e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_00239	7.24e-23	-	-	-	-	-	-	-	-
HMKIHHLC_00240	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HMKIHHLC_00241	4.99e-105	-	-	-	-	-	-	-	-
HMKIHHLC_00242	5.84e-253	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HMKIHHLC_00243	6.88e-86	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMKIHHLC_00244	3.68e-271	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HMKIHHLC_00245	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMKIHHLC_00246	1.55e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
HMKIHHLC_00247	2.7e-174	-	-	-	F	-	-	-	NUDIX domain
HMKIHHLC_00248	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HMKIHHLC_00249	3.41e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMKIHHLC_00250	4.37e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HMKIHHLC_00251	6.28e-249	-	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_00252	1.95e-195	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMKIHHLC_00253	3.72e-210	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMKIHHLC_00254	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00255	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_00256	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00257	1.24e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
HMKIHHLC_00258	1.54e-218	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HMKIHHLC_00259	1.31e-145	-	-	-	Q	-	-	-	Methyltransferase
HMKIHHLC_00260	1.78e-67	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HMKIHHLC_00261	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMKIHHLC_00262	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMKIHHLC_00263	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMKIHHLC_00264	5.26e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMKIHHLC_00265	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HMKIHHLC_00266	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMKIHHLC_00267	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMKIHHLC_00268	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HMKIHHLC_00269	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMKIHHLC_00270	1.3e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMKIHHLC_00271	1.42e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HMKIHHLC_00273	1.98e-157	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMKIHHLC_00274	6.93e-62	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMKIHHLC_00275	1.17e-67	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMKIHHLC_00276	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMKIHHLC_00278	1.91e-159	labL	-	-	S	-	-	-	Putative threonine/serine exporter
HMKIHHLC_00279	2.18e-288	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HMKIHHLC_00280	1.55e-145	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
HMKIHHLC_00281	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HMKIHHLC_00282	2.2e-253	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMKIHHLC_00283	7.42e-277	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_00284	1.17e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_00285	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMKIHHLC_00286	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HMKIHHLC_00287	4.3e-135	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HMKIHHLC_00288	2.81e-157	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMKIHHLC_00289	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HMKIHHLC_00290	3.04e-60	-	-	-	-	-	-	-	-
HMKIHHLC_00291	8.13e-263	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMKIHHLC_00292	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
HMKIHHLC_00294	1.5e-44	-	-	-	-	-	-	-	-
HMKIHHLC_00295	5.02e-52	-	-	-	-	-	-	-	-
HMKIHHLC_00296	5.57e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HMKIHHLC_00297	5.68e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMKIHHLC_00298	5.43e-191	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMKIHHLC_00301	2.42e-50	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMKIHHLC_00302	1.72e-77	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMKIHHLC_00303	4.51e-189	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HMKIHHLC_00304	6.39e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_00305	2.4e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_00306	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HMKIHHLC_00307	2.44e-82	-	-	-	S	-	-	-	YtxH-like protein
HMKIHHLC_00308	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMKIHHLC_00309	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMKIHHLC_00310	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HMKIHHLC_00311	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HMKIHHLC_00312	1.3e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HMKIHHLC_00313	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMKIHHLC_00314	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HMKIHHLC_00316	1.97e-88	-	-	-	-	-	-	-	-
HMKIHHLC_00317	4.04e-32	-	-	-	-	-	-	-	-
HMKIHHLC_00318	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HMKIHHLC_00319	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMKIHHLC_00320	2.08e-68	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMKIHHLC_00321	1.44e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMKIHHLC_00322	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMKIHHLC_00323	3.42e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HMKIHHLC_00324	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
HMKIHHLC_00325	9.53e-80	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HMKIHHLC_00326	1.34e-153	lysR	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_00327	8.83e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMKIHHLC_00328	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMKIHHLC_00329	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HMKIHHLC_00330	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
HMKIHHLC_00331	3.85e-63	-	-	-	-	-	-	-	-
HMKIHHLC_00332	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMKIHHLC_00333	1.47e-143	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HMKIHHLC_00334	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HMKIHHLC_00335	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
HMKIHHLC_00336	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HMKIHHLC_00337	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMKIHHLC_00338	6.3e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMKIHHLC_00339	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMKIHHLC_00340	2.33e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HMKIHHLC_00341	1.44e-111	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMKIHHLC_00342	1.9e-86	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMKIHHLC_00343	5.35e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMKIHHLC_00344	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HMKIHHLC_00345	4.54e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMKIHHLC_00346	1.59e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMKIHHLC_00347	4.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMKIHHLC_00348	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
HMKIHHLC_00349	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMKIHHLC_00350	1.7e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HMKIHHLC_00352	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HMKIHHLC_00353	7.76e-152	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HMKIHHLC_00354	6.16e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
HMKIHHLC_00355	6.77e-201	-	-	-	-	-	-	-	-
HMKIHHLC_00356	4.18e-198	dkgB	-	-	S	-	-	-	reductase
HMKIHHLC_00357	3.83e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HMKIHHLC_00358	1.14e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMKIHHLC_00359	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_00360	7.46e-157	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HMKIHHLC_00361	3.96e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMKIHHLC_00362	4.89e-122	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMKIHHLC_00363	1.69e-58	-	-	-	-	-	-	-	-
HMKIHHLC_00364	1.56e-230	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
HMKIHHLC_00365	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HMKIHHLC_00366	4.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HMKIHHLC_00367	1.55e-169	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMKIHHLC_00368	3.33e-13	-	-	-	-	-	-	-	-
HMKIHHLC_00369	1.17e-16	-	-	-	-	-	-	-	-
HMKIHHLC_00370	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HMKIHHLC_00371	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HMKIHHLC_00372	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HMKIHHLC_00373	2.05e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMKIHHLC_00375	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMKIHHLC_00376	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HMKIHHLC_00377	2.34e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMKIHHLC_00378	4.46e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMKIHHLC_00379	1.56e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMKIHHLC_00380	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMKIHHLC_00381	1.28e-189	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMKIHHLC_00382	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HMKIHHLC_00383	7.24e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMKIHHLC_00384	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HMKIHHLC_00386	2.32e-67	-	-	-	-	-	-	-	-
HMKIHHLC_00387	1.53e-86	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
HMKIHHLC_00388	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HMKIHHLC_00389	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMKIHHLC_00390	5.27e-120	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMKIHHLC_00391	1.63e-117	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMKIHHLC_00392	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMKIHHLC_00393	9.71e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMKIHHLC_00394	6.32e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMKIHHLC_00395	9.75e-187	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
HMKIHHLC_00396	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HMKIHHLC_00397	2.76e-104	-	-	-	S	-	-	-	NusG domain II
HMKIHHLC_00398	4.18e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HMKIHHLC_00399	1.05e-228	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMKIHHLC_00402	3.82e-157	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
HMKIHHLC_00403	2.75e-244	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HMKIHHLC_00405	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HMKIHHLC_00406	3.14e-181	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMKIHHLC_00407	4.83e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMKIHHLC_00408	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMKIHHLC_00409	3.38e-103	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HMKIHHLC_00410	5.77e-216	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HMKIHHLC_00411	2.55e-137	-	-	-	-	-	-	-	-
HMKIHHLC_00413	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMKIHHLC_00414	4.53e-118	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMKIHHLC_00415	1.48e-60	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMKIHHLC_00416	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMKIHHLC_00417	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HMKIHHLC_00418	9.5e-39	-	-	-	-	-	-	-	-
HMKIHHLC_00419	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HMKIHHLC_00420	3.36e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HMKIHHLC_00422	8.67e-179	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMKIHHLC_00423	5.72e-193	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMKIHHLC_00424	5.87e-311	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HMKIHHLC_00425	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
HMKIHHLC_00426	3.25e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_00427	1.92e-123	-	-	-	-	-	-	-	-
HMKIHHLC_00428	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HMKIHHLC_00429	6.84e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HMKIHHLC_00430	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
HMKIHHLC_00431	6.46e-83	-	-	-	-	-	-	-	-
HMKIHHLC_00432	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMKIHHLC_00433	3.4e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HMKIHHLC_00434	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMKIHHLC_00435	1.81e-277	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_00436	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
HMKIHHLC_00437	2.01e-212	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMKIHHLC_00438	4.49e-197	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMKIHHLC_00439	3.93e-184	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00440	4.08e-112	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00441	1.24e-89	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00442	5.02e-186	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HMKIHHLC_00443	3.25e-224	-	-	-	K	-	-	-	sugar-binding domain protein
HMKIHHLC_00444	4.08e-311	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HMKIHHLC_00445	5.41e-171	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HMKIHHLC_00446	5.82e-130	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
HMKIHHLC_00447	5.39e-152	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HMKIHHLC_00448	1.77e-237	-	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HMKIHHLC_00449	1.05e-146	dhaL	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	S	ko:K00863,ko:K05879	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak2
HMKIHHLC_00450	1.83e-279	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HMKIHHLC_00451	5.44e-198	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMKIHHLC_00452	5.6e-170	-	-	-	G	ko:K17466	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00453	5.98e-111	-	2.7.1.203	-	G	ko:K17465	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00454	5.33e-98	-	2.7.1.191, 2.7.1.203	-	G	ko:K02793,ko:K17464	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00455	1.5e-187	-	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HMKIHHLC_00456	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_00457	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
HMKIHHLC_00458	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HMKIHHLC_00459	1.23e-192	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMKIHHLC_00460	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HMKIHHLC_00461	5.58e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HMKIHHLC_00462	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HMKIHHLC_00463	4.35e-268	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
HMKIHHLC_00464	7.64e-51	-	-	-	-	-	-	-	-
HMKIHHLC_00465	2.9e-220	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HMKIHHLC_00466	7.14e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKIHHLC_00467	5.66e-278	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMKIHHLC_00469	6.21e-59	-	-	-	-	-	-	-	-
HMKIHHLC_00470	2.21e-164	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HMKIHHLC_00471	1.62e-93	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HMKIHHLC_00472	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HMKIHHLC_00474	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HMKIHHLC_00475	2.99e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMKIHHLC_00476	1.35e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HMKIHHLC_00477	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
HMKIHHLC_00478	8.69e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HMKIHHLC_00479	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HMKIHHLC_00480	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMKIHHLC_00481	5.92e-150	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HMKIHHLC_00482	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMKIHHLC_00483	7.41e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMKIHHLC_00484	3.27e-151	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HMKIHHLC_00485	1.46e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HMKIHHLC_00486	9.98e-73	-	-	-	-	-	-	-	-
HMKIHHLC_00487	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HMKIHHLC_00488	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HMKIHHLC_00489	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMKIHHLC_00490	6.14e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HMKIHHLC_00491	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HMKIHHLC_00492	4.4e-139	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HMKIHHLC_00493	8.42e-156	-	-	-	K	ko:K19505	-	ko00000,ko03000	Sigma-54 interaction domain
HMKIHHLC_00494	1.91e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HMKIHHLC_00495	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HMKIHHLC_00496	3.15e-103	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HMKIHHLC_00497	7.37e-223	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMKIHHLC_00498	8.68e-106	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00499	1.08e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00500	4.97e-220	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HMKIHHLC_00501	7.46e-233	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
HMKIHHLC_00502	1.4e-173	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
HMKIHHLC_00503	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HMKIHHLC_00504	1.21e-98	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00505	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00506	2.7e-291	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HMKIHHLC_00507	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00508	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00509	8.51e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMKIHHLC_00510	8.73e-154	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_00511	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HMKIHHLC_00512	5.58e-272	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMKIHHLC_00513	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HMKIHHLC_00514	2.69e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMKIHHLC_00515	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_00516	7.15e-156	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
HMKIHHLC_00517	8.68e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMKIHHLC_00518	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_00519	0.0	yycH	-	-	S	-	-	-	YycH protein
HMKIHHLC_00520	7.09e-181	yycI	-	-	S	-	-	-	YycH protein
HMKIHHLC_00521	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HMKIHHLC_00522	1.98e-283	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HMKIHHLC_00523	1.21e-53	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMKIHHLC_00524	1.8e-99	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMKIHHLC_00525	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HMKIHHLC_00526	2.34e-75	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HMKIHHLC_00527	1.78e-45	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HMKIHHLC_00528	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HMKIHHLC_00529	3.43e-212	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HMKIHHLC_00530	6.8e-161	-	-	-	M	-	-	-	domain protein
HMKIHHLC_00531	2.93e-235	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HMKIHHLC_00532	1.23e-255	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMKIHHLC_00533	4.78e-164	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_00534	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMKIHHLC_00535	9.02e-163	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HMKIHHLC_00536	3.45e-251	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMKIHHLC_00537	7.62e-178	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HMKIHHLC_00538	2.09e-266	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMKIHHLC_00539	3.27e-117	-	-	-	-	-	-	-	-
HMKIHHLC_00540	2.66e-144	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_00541	8.58e-105	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_00542	1.65e-103	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
HMKIHHLC_00543	5.69e-262	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMKIHHLC_00544	6.76e-145	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_00545	7.13e-222	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMKIHHLC_00546	1.65e-19	-	-	-	-	-	-	-	-
HMKIHHLC_00547	5.93e-59	-	-	-	-	-	-	-	-
HMKIHHLC_00548	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMKIHHLC_00549	1.21e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMKIHHLC_00550	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00551	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HMKIHHLC_00552	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_00553	1.68e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HMKIHHLC_00554	2.16e-238	lipA	-	-	I	-	-	-	Carboxylesterase family
HMKIHHLC_00555	3.29e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMKIHHLC_00556	1.87e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMKIHHLC_00558	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HMKIHHLC_00559	2.3e-23	-	-	-	-	-	-	-	-
HMKIHHLC_00560	4.75e-212	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMKIHHLC_00561	1.28e-84	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMKIHHLC_00562	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_00563	5.25e-151	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HMKIHHLC_00564	3.81e-277	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HMKIHHLC_00565	1.41e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HMKIHHLC_00566	1.2e-188	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMKIHHLC_00567	3.86e-170	yttB	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_00568	6.57e-91	yttB	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_00569	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMKIHHLC_00570	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HMKIHHLC_00571	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMKIHHLC_00572	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMKIHHLC_00573	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMKIHHLC_00574	4.26e-271	camS	-	-	S	-	-	-	sex pheromone
HMKIHHLC_00575	4.09e-228	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMKIHHLC_00576	4.12e-311	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMKIHHLC_00577	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
HMKIHHLC_00578	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HMKIHHLC_00579	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HMKIHHLC_00580	1.92e-80	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HMKIHHLC_00581	2.31e-19	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HMKIHHLC_00582	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMKIHHLC_00583	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMKIHHLC_00584	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HMKIHHLC_00585	7.66e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HMKIHHLC_00586	2.6e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMKIHHLC_00587	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMKIHHLC_00588	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HMKIHHLC_00589	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMKIHHLC_00590	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HMKIHHLC_00591	3.63e-270	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HMKIHHLC_00592	7.18e-79	-	-	-	-	-	-	-	-
HMKIHHLC_00593	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
HMKIHHLC_00594	1.25e-167	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_00595	1.09e-222	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HMKIHHLC_00596	1.75e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HMKIHHLC_00597	6.36e-277	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HMKIHHLC_00598	1.07e-43	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_00599	6.04e-94	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_00600	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
HMKIHHLC_00601	2.07e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMKIHHLC_00602	6.09e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HMKIHHLC_00603	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMKIHHLC_00604	4.97e-170	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMKIHHLC_00605	1.37e-160	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMKIHHLC_00606	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMKIHHLC_00607	3.22e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HMKIHHLC_00608	2.5e-296	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMKIHHLC_00609	2.06e-144	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMKIHHLC_00610	1.56e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMKIHHLC_00612	3.47e-147	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMKIHHLC_00613	6.41e-92	-	-	-	K	-	-	-	MarR family
HMKIHHLC_00614	7.13e-29	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ABC transporter
HMKIHHLC_00615	3.21e-247	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HMKIHHLC_00616	4.11e-241	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HMKIHHLC_00617	2.55e-245	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HMKIHHLC_00618	5.86e-187	-	-	-	S	-	-	-	hydrolase
HMKIHHLC_00619	4.04e-79	-	-	-	-	-	-	-	-
HMKIHHLC_00620	1.99e-16	-	-	-	-	-	-	-	-
HMKIHHLC_00621	3.43e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HMKIHHLC_00622	6.36e-161	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HMKIHHLC_00623	1.7e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMKIHHLC_00624	3.81e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMKIHHLC_00625	4.39e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HMKIHHLC_00626	3.35e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
HMKIHHLC_00627	4.84e-236	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMKIHHLC_00628	1.27e-153	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HMKIHHLC_00629	2.29e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HMKIHHLC_00630	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HMKIHHLC_00631	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HMKIHHLC_00632	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMKIHHLC_00633	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HMKIHHLC_00634	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMKIHHLC_00635	1.03e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMKIHHLC_00636	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMKIHHLC_00637	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMKIHHLC_00638	6.88e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMKIHHLC_00639	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMKIHHLC_00640	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HMKIHHLC_00641	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMKIHHLC_00642	1.42e-76	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMKIHHLC_00643	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMKIHHLC_00644	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMKIHHLC_00645	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMKIHHLC_00646	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMKIHHLC_00647	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMKIHHLC_00648	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMKIHHLC_00649	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HMKIHHLC_00650	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMKIHHLC_00651	2.01e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMKIHHLC_00652	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMKIHHLC_00653	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMKIHHLC_00654	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HMKIHHLC_00655	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMKIHHLC_00656	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMKIHHLC_00657	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKIHHLC_00658	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HMKIHHLC_00659	3.49e-129	-	-	-	-	-	-	-	-
HMKIHHLC_00660	6.13e-186	-	-	-	M	-	-	-	Heparinase II/III N-terminus
HMKIHHLC_00661	8.29e-221	-	-	-	M	-	-	-	Heparinase II/III N-terminus
HMKIHHLC_00663	2.81e-106	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00664	3.51e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_00665	7.99e-185	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00666	9.97e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00667	1.43e-294	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HMKIHHLC_00668	3.73e-202	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMKIHHLC_00669	1.82e-178	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HMKIHHLC_00670	8.85e-208	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMKIHHLC_00671	2.6e-192	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMKIHHLC_00672	2.82e-154	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HMKIHHLC_00673	1.94e-247	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HMKIHHLC_00674	6.42e-154	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HMKIHHLC_00675	1.45e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMKIHHLC_00676	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMKIHHLC_00677	4.17e-149	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HMKIHHLC_00678	4.15e-155	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMKIHHLC_00679	1.51e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HMKIHHLC_00680	7.11e-60	-	-	-	-	-	-	-	-
HMKIHHLC_00681	2.65e-58	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HMKIHHLC_00682	6.77e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMKIHHLC_00683	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
HMKIHHLC_00684	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMKIHHLC_00685	4.44e-229	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMKIHHLC_00686	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMKIHHLC_00687	4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMKIHHLC_00688	3.57e-201	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMKIHHLC_00689	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMKIHHLC_00690	3.25e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMKIHHLC_00691	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMKIHHLC_00692	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
HMKIHHLC_00693	1.19e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HMKIHHLC_00694	6.94e-119	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
HMKIHHLC_00695	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HMKIHHLC_00696	7.04e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HMKIHHLC_00697	7.91e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HMKIHHLC_00698	3.19e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HMKIHHLC_00699	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMKIHHLC_00701	4.8e-28	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HMKIHHLC_00702	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HMKIHHLC_00703	8.56e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMKIHHLC_00704	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HMKIHHLC_00705	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMKIHHLC_00706	2.05e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMKIHHLC_00707	1.65e-278	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HMKIHHLC_00708	6.88e-73	-	-	-	-	-	-	-	-
HMKIHHLC_00710	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HMKIHHLC_00711	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMKIHHLC_00712	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMKIHHLC_00714	2.55e-121	-	-	-	F	-	-	-	NUDIX domain
HMKIHHLC_00715	4.78e-183	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMKIHHLC_00716	9.15e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HMKIHHLC_00717	5.43e-166	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMKIHHLC_00718	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMKIHHLC_00719	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HMKIHHLC_00720	7.4e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HMKIHHLC_00721	7.54e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMKIHHLC_00722	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMKIHHLC_00723	4.66e-105	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HMKIHHLC_00724	1.46e-196	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HMKIHHLC_00725	4.29e-116	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HMKIHHLC_00726	1.27e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMKIHHLC_00727	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMKIHHLC_00728	5.67e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HMKIHHLC_00729	6.41e-24	-	-	-	-	-	-	-	-
HMKIHHLC_00730	7.61e-218	-	-	-	-	-	-	-	-
HMKIHHLC_00732	6.23e-123	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HMKIHHLC_00733	4.7e-50	-	-	-	-	-	-	-	-
HMKIHHLC_00734	5.77e-204	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HMKIHHLC_00735	1.05e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMKIHHLC_00736	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMKIHHLC_00737	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMKIHHLC_00738	1.67e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
HMKIHHLC_00739	2.82e-196	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HMKIHHLC_00740	2.27e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HMKIHHLC_00741	8.05e-86	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMKIHHLC_00742	2.95e-63	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMKIHHLC_00743	3.87e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HMKIHHLC_00744	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMKIHHLC_00745	2.19e-66	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMKIHHLC_00746	2.52e-184	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMKIHHLC_00747	1.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HMKIHHLC_00748	7.25e-56	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMKIHHLC_00749	3.05e-168	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMKIHHLC_00750	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMKIHHLC_00751	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMKIHHLC_00752	7.52e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HMKIHHLC_00753	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMKIHHLC_00754	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HMKIHHLC_00755	4.69e-301	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HMKIHHLC_00756	6.78e-100	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HMKIHHLC_00757	6.6e-219	-	-	-	S	-	-	-	EpsG family
HMKIHHLC_00758	1.81e-99	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HMKIHHLC_00759	1.7e-118	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
HMKIHHLC_00760	4.32e-305	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HMKIHHLC_00761	4.4e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMKIHHLC_00762	2.98e-126	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
HMKIHHLC_00763	2.44e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMKIHHLC_00764	7.24e-296	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HMKIHHLC_00765	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMKIHHLC_00766	4.74e-50	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HMKIHHLC_00767	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMKIHHLC_00768	4.45e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMKIHHLC_00769	4.66e-44	-	-	-	-	-	-	-	-
HMKIHHLC_00770	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMKIHHLC_00771	1.63e-111	queT	-	-	S	-	-	-	QueT transporter
HMKIHHLC_00772	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HMKIHHLC_00773	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMKIHHLC_00774	9.79e-168	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMKIHHLC_00775	1.34e-154	-	-	-	S	-	-	-	(CBS) domain
HMKIHHLC_00776	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HMKIHHLC_00777	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMKIHHLC_00778	2.18e-136	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HMKIHHLC_00779	2.34e-152	-	-	-	F	-	-	-	glutamine amidotransferase
HMKIHHLC_00780	1.05e-173	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HMKIHHLC_00781	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HMKIHHLC_00782	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMKIHHLC_00783	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMKIHHLC_00784	7.96e-127	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
HMKIHHLC_00785	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMKIHHLC_00786	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMKIHHLC_00787	0.0	ydaO	-	-	E	-	-	-	amino acid
HMKIHHLC_00788	6.3e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HMKIHHLC_00789	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HMKIHHLC_00790	7.51e-194	-	-	-	S	-	-	-	hydrolase
HMKIHHLC_00791	1.81e-59	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HMKIHHLC_00792	9.48e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HMKIHHLC_00793	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00794	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00795	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_00796	3.64e-244	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HMKIHHLC_00797	2.89e-313	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HMKIHHLC_00798	3.05e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00799	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMKIHHLC_00800	1.96e-156	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMKIHHLC_00801	1.94e-248	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMKIHHLC_00802	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HMKIHHLC_00803	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HMKIHHLC_00804	3.24e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMKIHHLC_00805	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMKIHHLC_00806	4.1e-152	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMKIHHLC_00807	8.24e-306	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_00808	2.17e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMKIHHLC_00809	1.16e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_00810	3.01e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HMKIHHLC_00811	1.1e-182	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMKIHHLC_00812	5.46e-177	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMKIHHLC_00813	1.32e-272	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HMKIHHLC_00815	1.02e-97	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMKIHHLC_00816	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMKIHHLC_00817	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMKIHHLC_00818	3.1e-313	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMKIHHLC_00819	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_00820	1.76e-282	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMKIHHLC_00821	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMKIHHLC_00822	1.13e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMKIHHLC_00823	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HMKIHHLC_00824	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HMKIHHLC_00825	9.98e-88	-	-	-	-	-	-	-	-
HMKIHHLC_00826	6.52e-98	-	-	-	O	-	-	-	OsmC-like protein
HMKIHHLC_00827	5.06e-316	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HMKIHHLC_00828	4.53e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HMKIHHLC_00829	5.82e-95	-	-	-	S	-	-	-	ASCH
HMKIHHLC_00830	5.36e-33	-	-	-	-	-	-	-	-
HMKIHHLC_00831	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMKIHHLC_00832	9.45e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMKIHHLC_00833	2.66e-80	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMKIHHLC_00834	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMKIHHLC_00835	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMKIHHLC_00836	1.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMKIHHLC_00837	8.81e-288	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HMKIHHLC_00838	9.36e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMKIHHLC_00839	2.83e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMKIHHLC_00840	4.46e-183	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HMKIHHLC_00841	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMKIHHLC_00842	4.37e-226	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMKIHHLC_00843	9.31e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMKIHHLC_00846	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HMKIHHLC_00847	2.18e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HMKIHHLC_00848	1.63e-233	arbY	-	-	M	-	-	-	family 8
HMKIHHLC_00849	2.36e-211	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HMKIHHLC_00850	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
HMKIHHLC_00851	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMKIHHLC_00852	4.05e-79	-	-	-	-	-	-	-	-
HMKIHHLC_00853	1.02e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HMKIHHLC_00855	8.03e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HMKIHHLC_00856	3.85e-31	-	-	-	-	-	-	-	-
HMKIHHLC_00858	2.86e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
HMKIHHLC_00859	1.2e-67	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
HMKIHHLC_00860	3.67e-109	-	-	-	-	-	-	-	-
HMKIHHLC_00861	1.5e-229	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMKIHHLC_00862	1.22e-181	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00863	8.6e-167	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_00864	6e-287	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HMKIHHLC_00865	8.68e-211	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HMKIHHLC_00866	2.97e-170	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HMKIHHLC_00867	1.91e-253	ydeM3	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HMKIHHLC_00868	4.26e-221	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HMKIHHLC_00869	7.79e-301	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
HMKIHHLC_00870	2.36e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMKIHHLC_00871	2.91e-175	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HMKIHHLC_00872	2.85e-205	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
HMKIHHLC_00873	9.9e-43	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMKIHHLC_00874	1.24e-225	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMKIHHLC_00875	7.25e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMKIHHLC_00876	1.32e-306	ytoI	-	-	K	-	-	-	DRTGG domain
HMKIHHLC_00877	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HMKIHHLC_00878	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMKIHHLC_00879	1.55e-223	-	-	-	-	-	-	-	-
HMKIHHLC_00880	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMKIHHLC_00882	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HMKIHHLC_00883	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMKIHHLC_00884	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HMKIHHLC_00885	2.84e-48	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMKIHHLC_00886	3.4e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
HMKIHHLC_00887	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HMKIHHLC_00888	5.66e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMKIHHLC_00889	2.82e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HMKIHHLC_00890	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMKIHHLC_00891	2.05e-156	-	-	-	-	-	-	-	-
HMKIHHLC_00892	6.84e-156	vanR	-	-	K	-	-	-	response regulator
HMKIHHLC_00893	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
HMKIHHLC_00894	2.75e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMKIHHLC_00895	2.62e-83	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMKIHHLC_00896	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMKIHHLC_00897	1.1e-181	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HMKIHHLC_00898	8.2e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
HMKIHHLC_00899	2.56e-186	gntR	-	-	K	-	-	-	rpiR family
HMKIHHLC_00900	3.74e-75	-	-	-	-	-	-	-	-
HMKIHHLC_00901	9.72e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMKIHHLC_00902	4.91e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMKIHHLC_00903	2.18e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMKIHHLC_00904	3.73e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HMKIHHLC_00905	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HMKIHHLC_00906	1.77e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMKIHHLC_00907	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMKIHHLC_00908	9.38e-101	-	-	-	T	-	-	-	Sh3 type 3 domain protein
HMKIHHLC_00909	7.68e-174	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HMKIHHLC_00910	2.32e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_00911	2.19e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HMKIHHLC_00912	2.56e-53	-	-	-	-	-	-	-	-
HMKIHHLC_00913	6.33e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HMKIHHLC_00914	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HMKIHHLC_00915	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMKIHHLC_00916	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00917	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HMKIHHLC_00918	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMKIHHLC_00919	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMKIHHLC_00920	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_00921	1.9e-235	-	-	-	-	-	-	-	-
HMKIHHLC_00922	1.01e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMKIHHLC_00923	6.1e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMKIHHLC_00924	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMKIHHLC_00925	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMKIHHLC_00926	7.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HMKIHHLC_00927	7.75e-145	-	-	-	P	-	-	-	Cation efflux family
HMKIHHLC_00928	1.53e-35	-	-	-	-	-	-	-	-
HMKIHHLC_00929	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HMKIHHLC_00930	1.04e-304	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMKIHHLC_00931	1.14e-72	-	-	-	-	-	-	-	-
HMKIHHLC_00932	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_00933	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMKIHHLC_00934	6.42e-28	-	-	-	-	-	-	-	-
HMKIHHLC_00935	1.05e-171	-	-	-	-	-	-	-	-
HMKIHHLC_00936	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMKIHHLC_00937	5.24e-116	-	-	-	-	-	-	-	-
HMKIHHLC_00938	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00939	1.88e-223	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HMKIHHLC_00940	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMKIHHLC_00941	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMKIHHLC_00942	2.03e-34	-	-	-	T	-	-	-	PFAM SpoVT AbrB
HMKIHHLC_00944	1.16e-115	-	-	-	-	-	-	-	-
HMKIHHLC_00945	7.24e-287	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HMKIHHLC_00946	4.38e-239	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMKIHHLC_00947	4.82e-60	sgcB	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00948	4.15e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_00949	1.17e-29	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HMKIHHLC_00950	1.2e-121	-	-	-	-	-	-	-	-
HMKIHHLC_00951	1.58e-131	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
HMKIHHLC_00952	3.55e-154	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
HMKIHHLC_00953	3.34e-33	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
HMKIHHLC_00954	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HMKIHHLC_00955	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HMKIHHLC_00956	1.63e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HMKIHHLC_00957	2.26e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMKIHHLC_00958	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HMKIHHLC_00959	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_00960	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_00961	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_00962	2.72e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_00963	0.0	-	-	-	M	-	-	-	domain protein
HMKIHHLC_00964	4.28e-131	-	-	-	-	-	-	-	-
HMKIHHLC_00965	3.79e-293	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMKIHHLC_00966	1.99e-262	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HMKIHHLC_00967	2.06e-143	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_00968	2.05e-72	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HMKIHHLC_00969	6.77e-81	-	-	-	-	-	-	-	-
HMKIHHLC_00970	3.49e-175	-	-	-	-	-	-	-	-
HMKIHHLC_00971	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HMKIHHLC_00972	8.59e-13	-	-	-	S	-	-	-	Enterocin A Immunity
HMKIHHLC_00973	1.79e-41	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
HMKIHHLC_00974	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMKIHHLC_00975	1.64e-151	-	-	-	S	-	-	-	Zeta toxin
HMKIHHLC_00976	1.31e-207	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMKIHHLC_00977	1.29e-92	-	-	-	-	-	-	-	-
HMKIHHLC_00978	1.96e-292	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMKIHHLC_00979	4.1e-67	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_00980	1.39e-223	-	-	-	GKT	-	-	-	transcriptional antiterminator
HMKIHHLC_00981	1.47e-266	-	-	-	GKT	-	-	-	transcriptional antiterminator
HMKIHHLC_00982	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
HMKIHHLC_00983	6.74e-173	-	-	-	-	-	-	-	-
HMKIHHLC_00984	2.61e-115	-	-	-	-	-	-	-	-
HMKIHHLC_00985	9.65e-163	-	-	-	-	-	-	-	-
HMKIHHLC_00986	1.2e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMKIHHLC_00987	1.43e-40	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
HMKIHHLC_00988	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKIHHLC_00989	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMKIHHLC_00990	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMKIHHLC_00991	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HMKIHHLC_01000	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMKIHHLC_01001	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMKIHHLC_01002	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMKIHHLC_01003	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMKIHHLC_01004	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HMKIHHLC_01005	1.77e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMKIHHLC_01006	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HMKIHHLC_01007	2.28e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMKIHHLC_01008	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HMKIHHLC_01009	6.07e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMKIHHLC_01010	3.17e-184	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HMKIHHLC_01011	2.5e-231	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HMKIHHLC_01012	2.42e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HMKIHHLC_01013	5.66e-94	-	-	-	-	-	-	-	-
HMKIHHLC_01014	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
HMKIHHLC_01016	1.64e-240	ynjC	-	-	S	-	-	-	Cell surface protein
HMKIHHLC_01017	2.04e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_01018	2e-167	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_01020	0.0	-	-	-	-	-	-	-	-
HMKIHHLC_01021	1.04e-134	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMKIHHLC_01022	5.45e-38	-	-	-	-	-	-	-	-
HMKIHHLC_01023	2.66e-224	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMKIHHLC_01024	9.87e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HMKIHHLC_01025	2.78e-124	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HMKIHHLC_01026	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMKIHHLC_01027	2.04e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMKIHHLC_01028	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HMKIHHLC_01029	3.15e-230	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMKIHHLC_01030	2e-24	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HMKIHHLC_01031	2.64e-144	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HMKIHHLC_01032	5.89e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HMKIHHLC_01033	1.29e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01034	8.33e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HMKIHHLC_01035	1.6e-222	ysaA	-	-	V	-	-	-	RDD family
HMKIHHLC_01036	3.29e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMKIHHLC_01037	6.3e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMKIHHLC_01038	2.56e-72	nudA	-	-	S	-	-	-	ASCH
HMKIHHLC_01039	1.68e-104	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HMKIHHLC_01040	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HMKIHHLC_01041	1.17e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMKIHHLC_01042	5.99e-143	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HMKIHHLC_01043	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HMKIHHLC_01044	4.62e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMKIHHLC_01045	1.89e-157	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
HMKIHHLC_01046	7.76e-195	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMKIHHLC_01047	1.66e-218	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
HMKIHHLC_01048	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HMKIHHLC_01049	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
HMKIHHLC_01050	2.8e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HMKIHHLC_01051	1.75e-225	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HMKIHHLC_01052	5.95e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HMKIHHLC_01053	4.9e-58	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HMKIHHLC_01054	5.1e-46	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HMKIHHLC_01055	1.25e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HMKIHHLC_01056	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HMKIHHLC_01057	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HMKIHHLC_01058	2.65e-269	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMKIHHLC_01059	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HMKIHHLC_01060	6.8e-21	-	-	-	-	-	-	-	-
HMKIHHLC_01061	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMKIHHLC_01062	7.57e-119	-	-	-	-	-	-	-	-
HMKIHHLC_01063	1.63e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMKIHHLC_01064	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMKIHHLC_01065	5.84e-226	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HMKIHHLC_01066	3.18e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HMKIHHLC_01068	1.71e-209	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01069	4.72e-271	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_01070	8.04e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMKIHHLC_01071	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HMKIHHLC_01072	5.54e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HMKIHHLC_01073	2.11e-139	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_01074	6.59e-76	-	-	-	-	-	-	-	-
HMKIHHLC_01075	1.94e-153	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_01076	4.53e-187	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMKIHHLC_01077	2.08e-30	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMKIHHLC_01078	1.2e-56	-	-	-	-	-	-	-	-
HMKIHHLC_01079	1.73e-225	-	-	-	S	-	-	-	Cell surface protein
HMKIHHLC_01080	3.81e-150	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_01081	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMKIHHLC_01082	2.93e-43	-	-	-	-	-	-	-	-
HMKIHHLC_01083	2.82e-36	-	-	-	-	-	-	-	-
HMKIHHLC_01084	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMKIHHLC_01085	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_01086	2.27e-109	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_01089	1.74e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMKIHHLC_01090	1.14e-216	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMKIHHLC_01091	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HMKIHHLC_01092	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMKIHHLC_01093	2.33e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMKIHHLC_01094	6.7e-132	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMKIHHLC_01095	4.86e-201	mleR	-	-	K	-	-	-	LysR family
HMKIHHLC_01096	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HMKIHHLC_01097	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HMKIHHLC_01098	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMKIHHLC_01099	2.28e-113	-	-	-	C	-	-	-	FMN binding
HMKIHHLC_01100	7.65e-223	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HMKIHHLC_01101	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_01102	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
HMKIHHLC_01103	3.86e-78	-	-	-	-	-	-	-	-
HMKIHHLC_01104	2.08e-259	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HMKIHHLC_01105	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMKIHHLC_01106	8.81e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HMKIHHLC_01107	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMKIHHLC_01108	5.31e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMKIHHLC_01109	2.95e-110	-	-	-	-	-	-	-	-
HMKIHHLC_01110	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01111	1.41e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMKIHHLC_01112	1.22e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMKIHHLC_01113	1.83e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HMKIHHLC_01114	1.02e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HMKIHHLC_01115	2.43e-205	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HMKIHHLC_01116	6.47e-208	-	-	-	S	-	-	-	KR domain
HMKIHHLC_01117	4.88e-213	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HMKIHHLC_01118	1.84e-115	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HMKIHHLC_01119	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HMKIHHLC_01120	4.26e-309	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HMKIHHLC_01121	7.45e-166	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HMKIHHLC_01122	3.08e-93	-	-	-	S	-	-	-	GtrA-like protein
HMKIHHLC_01123	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HMKIHHLC_01124	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
HMKIHHLC_01126	5.52e-286	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_01128	1.08e-24	-	-	-	-	-	-	-	-
HMKIHHLC_01129	8.95e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HMKIHHLC_01130	3.21e-205	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HMKIHHLC_01131	2.98e-171	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMKIHHLC_01132	1.81e-274	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMKIHHLC_01133	2.53e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMKIHHLC_01134	1.26e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMKIHHLC_01135	1.56e-204	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HMKIHHLC_01136	3.68e-180	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMKIHHLC_01137	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HMKIHHLC_01138	5.58e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMKIHHLC_01139	7.96e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HMKIHHLC_01140	4.79e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMKIHHLC_01141	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HMKIHHLC_01142	4.49e-232	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMKIHHLC_01143	6.11e-182	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HMKIHHLC_01144	4.1e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HMKIHHLC_01145	1.9e-195	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMKIHHLC_01146	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HMKIHHLC_01147	8.81e-277	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HMKIHHLC_01148	1.44e-103	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HMKIHHLC_01149	2.59e-97	-	-	-	S	-	-	-	NusG domain II
HMKIHHLC_01150	1.35e-208	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HMKIHHLC_01151	1.68e-183	-	-	-	-	-	-	-	-
HMKIHHLC_01152	3.3e-266	-	-	-	S	-	-	-	Membrane
HMKIHHLC_01153	7.61e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMKIHHLC_01155	5.11e-242	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HMKIHHLC_01156	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HMKIHHLC_01157	2.7e-62	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HMKIHHLC_01158	4.91e-55	-	-	-	-	-	-	-	-
HMKIHHLC_01159	2.02e-245	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMKIHHLC_01160	1.32e-71	-	-	-	-	-	-	-	-
HMKIHHLC_01161	1.03e-103	-	-	-	-	-	-	-	-
HMKIHHLC_01162	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HMKIHHLC_01163	1.58e-33	-	-	-	-	-	-	-	-
HMKIHHLC_01164	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMKIHHLC_01165	8.86e-60	-	-	-	-	-	-	-	-
HMKIHHLC_01166	8.47e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HMKIHHLC_01167	8.37e-116	-	-	-	S	-	-	-	Flavin reductase like domain
HMKIHHLC_01168	6.83e-91	-	-	-	-	-	-	-	-
HMKIHHLC_01169	2.81e-300	-	-	-	S	-	-	-	Phage tail protein
HMKIHHLC_01170	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HMKIHHLC_01171	2.72e-27	-	-	-	-	-	-	-	-
HMKIHHLC_01172	1.96e-92	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
HMKIHHLC_01173	2.16e-37	-	-	-	-	-	-	-	-
HMKIHHLC_01174	1.9e-86	-	-	-	S	-	-	-	exonuclease activity
HMKIHHLC_01175	8.85e-184	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HMKIHHLC_01176	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMKIHHLC_01177	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMKIHHLC_01178	5.33e-235	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMKIHHLC_01179	9.49e-196	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMKIHHLC_01180	3.12e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMKIHHLC_01181	5.83e-73	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMKIHHLC_01182	8.91e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMKIHHLC_01183	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HMKIHHLC_01184	2.25e-284	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HMKIHHLC_01185	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_01186	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01187	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMKIHHLC_01188	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HMKIHHLC_01189	2.28e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HMKIHHLC_01190	9.48e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMKIHHLC_01191	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMKIHHLC_01192	9.82e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMKIHHLC_01193	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMKIHHLC_01194	3.48e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HMKIHHLC_01195	2.83e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HMKIHHLC_01196	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HMKIHHLC_01197	1.41e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HMKIHHLC_01198	5.04e-236	-	-	-	S	-	-	-	DUF218 domain
HMKIHHLC_01199	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMKIHHLC_01201	9.02e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMKIHHLC_01202	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMKIHHLC_01203	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HMKIHHLC_01204	3.93e-312	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HMKIHHLC_01205	2.2e-187	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HMKIHHLC_01206	2.86e-55	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HMKIHHLC_01207	6.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HMKIHHLC_01208	7.28e-138	-	-	-	S	-	-	-	CYTH
HMKIHHLC_01209	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HMKIHHLC_01210	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMKIHHLC_01211	2.88e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMKIHHLC_01212	2.73e-128	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMKIHHLC_01213	9.04e-29	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMKIHHLC_01214	2.23e-50	-	-	-	-	-	-	-	-
HMKIHHLC_01215	1.54e-144	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HMKIHHLC_01216	1e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HMKIHHLC_01217	1.43e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HMKIHHLC_01218	1.49e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMKIHHLC_01219	5.49e-58	-	-	-	-	-	-	-	-
HMKIHHLC_01220	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMKIHHLC_01221	1.59e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMKIHHLC_01222	3.87e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
HMKIHHLC_01223	8.06e-314	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HMKIHHLC_01224	2.36e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
HMKIHHLC_01225	1.94e-110	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HMKIHHLC_01226	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HMKIHHLC_01227	1.64e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HMKIHHLC_01228	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
HMKIHHLC_01229	9.32e-112	ykuL	-	-	S	-	-	-	CBS domain
HMKIHHLC_01230	2.2e-145	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HMKIHHLC_01231	1.07e-22	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HMKIHHLC_01232	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HMKIHHLC_01233	2.12e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMKIHHLC_01234	1.39e-113	ytxH	-	-	S	-	-	-	YtxH-like protein
HMKIHHLC_01235	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HMKIHHLC_01236	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMKIHHLC_01238	3.23e-59	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMKIHHLC_01239	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
HMKIHHLC_01240	1.29e-277	-	-	-	S	-	-	-	Phage portal protein
HMKIHHLC_01241	6.06e-29	-	-	-	-	-	-	-	-
HMKIHHLC_01242	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HMKIHHLC_01243	1.56e-103	terS	-	-	L	-	-	-	Phage terminase, small subunit
HMKIHHLC_01244	1.19e-30	-	-	-	L	-	-	-	HNH endonuclease
HMKIHHLC_01246	5.61e-71	-	-	-	S	-	-	-	Phage head-tail joining protein
HMKIHHLC_01247	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HMKIHHLC_01248	4.14e-146	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HMKIHHLC_01249	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01250	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01251	3.33e-28	-	-	-	-	-	-	-	-
HMKIHHLC_01252	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HMKIHHLC_01253	3.9e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HMKIHHLC_01254	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMKIHHLC_01255	3.19e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMKIHHLC_01256	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HMKIHHLC_01257	6.48e-125	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMKIHHLC_01258	2.66e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HMKIHHLC_01259	2.6e-232	-	-	-	K	-	-	-	LysR substrate binding domain
HMKIHHLC_01260	2.56e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMKIHHLC_01261	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HMKIHHLC_01262	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMKIHHLC_01263	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMKIHHLC_01264	5.08e-242	-	-	-	M	-	-	-	domain protein
HMKIHHLC_01265	7.04e-102	-	-	-	-	-	-	-	-
HMKIHHLC_01266	8.09e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HMKIHHLC_01267	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
HMKIHHLC_01268	6.75e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMKIHHLC_01269	6.85e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMKIHHLC_01270	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HMKIHHLC_01271	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMKIHHLC_01272	5.89e-185	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMKIHHLC_01273	6.58e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMKIHHLC_01274	2.01e-302	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HMKIHHLC_01275	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HMKIHHLC_01276	1.68e-104	-	-	-	M	-	-	-	Lysin motif
HMKIHHLC_01277	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMKIHHLC_01278	6.87e-230	-	-	-	S	-	-	-	Helix-turn-helix domain
HMKIHHLC_01279	1.11e-58	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HMKIHHLC_01280	4.35e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMKIHHLC_01281	3.15e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMKIHHLC_01282	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMKIHHLC_01283	5.56e-38	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMKIHHLC_01284	2.33e-87	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMKIHHLC_01285	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMKIHHLC_01286	1.05e-157	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HMKIHHLC_01287	8.05e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HMKIHHLC_01289	1.94e-251	-	-	-	-	-	-	-	-
HMKIHHLC_01290	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMKIHHLC_01291	1.92e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMKIHHLC_01292	2.6e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMKIHHLC_01294	1.76e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HMKIHHLC_01295	2.23e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMKIHHLC_01296	8.54e-270	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HMKIHHLC_01297	7.33e-203	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_01298	2.88e-96	-	-	-	-	-	-	-	-
HMKIHHLC_01299	1.43e-197	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01300	2.83e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMKIHHLC_01301	2.36e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01302	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HMKIHHLC_01303	1.4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
HMKIHHLC_01305	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HMKIHHLC_01306	8.92e-271	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMKIHHLC_01307	2.25e-201	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
HMKIHHLC_01308	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HMKIHHLC_01309	0.0	-	-	-	M	-	-	-	domain protein
HMKIHHLC_01310	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMKIHHLC_01311	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMKIHHLC_01312	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMKIHHLC_01313	1.18e-255	-	-	-	K	-	-	-	WYL domain
HMKIHHLC_01314	1.66e-193	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMKIHHLC_01315	1.15e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HMKIHHLC_01316	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HMKIHHLC_01317	7.91e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HMKIHHLC_01318	1.11e-242	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HMKIHHLC_01319	5.97e-215	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HMKIHHLC_01320	4.43e-185	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMKIHHLC_01321	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HMKIHHLC_01322	8.38e-188	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HMKIHHLC_01323	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HMKIHHLC_01324	1.38e-198	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HMKIHHLC_01325	1.55e-184	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HMKIHHLC_01326	1.06e-113	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HMKIHHLC_01327	3.67e-151	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMKIHHLC_01328	8.05e-190	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMKIHHLC_01329	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HMKIHHLC_01330	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HMKIHHLC_01331	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMKIHHLC_01332	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMKIHHLC_01333	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMKIHHLC_01334	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMKIHHLC_01335	3.93e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMKIHHLC_01336	1.46e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMKIHHLC_01337	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMKIHHLC_01338	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMKIHHLC_01339	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMKIHHLC_01340	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMKIHHLC_01341	2.35e-70	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMKIHHLC_01342	6.02e-95	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01343	1.09e-152	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01344	1.12e-304	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HMKIHHLC_01346	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
HMKIHHLC_01347	1.64e-184	-	-	-	M	-	-	-	hydrolase, family 25
HMKIHHLC_01348	2.9e-171	ypiA	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMKIHHLC_01349	1.25e-148	-	-	-	C	-	-	-	Flavodoxin
HMKIHHLC_01350	6.23e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_01351	8.08e-238	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01352	7.08e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01353	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HMKIHHLC_01354	3.4e-82	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HMKIHHLC_01355	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMKIHHLC_01356	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMKIHHLC_01357	1.69e-313	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HMKIHHLC_01358	1.94e-124	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
HMKIHHLC_01359	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_01360	3.31e-44	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_01361	2.09e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMKIHHLC_01362	1.62e-191	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMKIHHLC_01363	1.88e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMKIHHLC_01364	4.35e-282	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMKIHHLC_01365	1.71e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HMKIHHLC_01366	1.41e-285	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HMKIHHLC_01367	3.41e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HMKIHHLC_01368	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HMKIHHLC_01369	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HMKIHHLC_01370	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HMKIHHLC_01371	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HMKIHHLC_01372	3.93e-93	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HMKIHHLC_01373	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HMKIHHLC_01374	7.21e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HMKIHHLC_01375	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HMKIHHLC_01377	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMKIHHLC_01378	2.18e-61	-	-	-	-	-	-	-	-
HMKIHHLC_01380	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMKIHHLC_01381	1.93e-213	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMKIHHLC_01382	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMKIHHLC_01383	3.31e-282	-	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_01384	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMKIHHLC_01385	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMKIHHLC_01386	4.31e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMKIHHLC_01387	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMKIHHLC_01388	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
HMKIHHLC_01389	1.08e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMKIHHLC_01390	6.51e-37	-	-	-	S	-	-	-	peptidase activity
HMKIHHLC_01391	6.47e-275	-	-	-	S	-	-	-	peptidase activity
HMKIHHLC_01392	1.84e-146	-	-	-	S	-	-	-	peptidase activity
HMKIHHLC_01393	4.89e-301	-	-	-	S	-	-	-	Phage portal protein
HMKIHHLC_01395	0.0	-	-	-	S	-	-	-	Phage Terminase
HMKIHHLC_01396	1.78e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HMKIHHLC_01397	1.64e-24	-	-	-	L	-	-	-	HNH nucleases
HMKIHHLC_01398	7.31e-53	-	-	-	L	-	-	-	HNH nucleases
HMKIHHLC_01399	9.7e-117	-	-	-	-	-	-	-	-
HMKIHHLC_01401	4.37e-68	-	-	-	-	-	-	-	-
HMKIHHLC_01402	2.91e-92	-	-	-	S	-	-	-	HNH endonuclease
HMKIHHLC_01404	5.88e-131	-	-	-	-	-	-	-	-
HMKIHHLC_01405	3.83e-142	-	-	-	S	-	-	-	Membrane
HMKIHHLC_01406	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMKIHHLC_01408	2.96e-72	-	-	-	-	-	-	-	-
HMKIHHLC_01409	2.37e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMKIHHLC_01411	3.84e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_01412	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
HMKIHHLC_01413	4.71e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMKIHHLC_01414	3.63e-284	-	-	-	E	-	-	-	Amino acid permease
HMKIHHLC_01415	6.86e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMKIHHLC_01416	7.88e-210	-	-	-	S	-	-	-	reductase
HMKIHHLC_01417	2.35e-69	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMKIHHLC_01418	6.99e-112	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMKIHHLC_01419	4.55e-76	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMKIHHLC_01420	1.68e-124	-	-	-	-	-	-	-	-
HMKIHHLC_01421	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_01422	1.54e-75	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMKIHHLC_01423	3.96e-293	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_01424	4.8e-66	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_01425	1.75e-226	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMKIHHLC_01426	9.61e-289	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HMKIHHLC_01427	3.05e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HMKIHHLC_01428	9.14e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HMKIHHLC_01429	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HMKIHHLC_01430	6.69e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
HMKIHHLC_01431	2.47e-190	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
HMKIHHLC_01432	2.33e-184	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HMKIHHLC_01433	3.26e-07	-	-	-	-	-	-	-	-
HMKIHHLC_01434	1.01e-226	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMKIHHLC_01435	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HMKIHHLC_01436	2.14e-200	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HMKIHHLC_01437	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HMKIHHLC_01438	2.17e-76	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMKIHHLC_01439	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
HMKIHHLC_01440	1.19e-162	citR	-	-	K	-	-	-	FCD
HMKIHHLC_01441	5.7e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMKIHHLC_01442	7.95e-21	-	-	-	-	-	-	-	-
HMKIHHLC_01443	4.93e-70	-	-	-	-	-	-	-	-
HMKIHHLC_01444	8.96e-253	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HMKIHHLC_01445	1.97e-220	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HMKIHHLC_01447	7.21e-62	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HMKIHHLC_01448	1.23e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HMKIHHLC_01449	8.42e-156	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_01450	6.77e-49	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
HMKIHHLC_01451	5.54e-214	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01452	2.58e-176	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HMKIHHLC_01453	4.64e-84	ORF00048	-	-	-	-	-	-	-
HMKIHHLC_01454	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HMKIHHLC_01455	6.38e-136	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMKIHHLC_01456	2.61e-59	-	-	-	K	-	-	-	GNAT family
HMKIHHLC_01457	1.09e-134	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HMKIHHLC_01458	3.61e-55	-	-	-	-	-	-	-	-
HMKIHHLC_01459	4.75e-306	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HMKIHHLC_01460	2.14e-69	-	-	-	-	-	-	-	-
HMKIHHLC_01461	1.76e-59	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
HMKIHHLC_01463	1.57e-281	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01464	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01465	7.15e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMKIHHLC_01466	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01468	2.34e-140	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HMKIHHLC_01469	8.4e-32	-	-	-	-	-	-	-	-
HMKIHHLC_01470	7.1e-224	ccpB	-	-	K	-	-	-	lacI family
HMKIHHLC_01471	9.79e-103	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_01472	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_01473	6.63e-203	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMKIHHLC_01474	4.74e-30	-	-	-	-	-	-	-	-
HMKIHHLC_01475	8.98e-209	-	-	-	S	-	-	-	zinc-ribbon domain
HMKIHHLC_01476	2.41e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_01477	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
HMKIHHLC_01478	6.71e-73	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMKIHHLC_01479	5.63e-80	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMKIHHLC_01480	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
HMKIHHLC_01481	2.6e-120	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMKIHHLC_01482	3.72e-72	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMKIHHLC_01483	3.2e-153	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_01484	5.02e-235	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_01485	2.87e-23	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HMKIHHLC_01486	7.62e-177	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
HMKIHHLC_01487	2.08e-265	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HMKIHHLC_01489	1.33e-228	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HMKIHHLC_01490	7.17e-79	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HMKIHHLC_01491	2.46e-73	-	-	-	-	-	-	-	-
HMKIHHLC_01492	1.53e-88	-	-	-	-	-	-	-	-
HMKIHHLC_01493	7.36e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HMKIHHLC_01494	7.39e-20	-	-	-	-	-	-	-	-
HMKIHHLC_01495	4.67e-97	-	-	-	S	-	-	-	acetyltransferase
HMKIHHLC_01496	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HMKIHHLC_01498	3.25e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HMKIHHLC_01499	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMKIHHLC_01500	1.6e-99	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HMKIHHLC_01501	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMKIHHLC_01502	1.05e-211	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMKIHHLC_01503	5.7e-197	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMKIHHLC_01504	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HMKIHHLC_01505	1.81e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HMKIHHLC_01506	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HMKIHHLC_01508	6.98e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_01509	2.88e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01510	1.44e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01511	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMKIHHLC_01512	1.97e-124	-	-	-	K	-	-	-	Cupin domain
HMKIHHLC_01513	2.7e-67	-	-	-	-	-	-	-	-
HMKIHHLC_01515	1.87e-64	-	-	-	S	-	-	-	methyltransferase activity
HMKIHHLC_01516	1.53e-66	-	-	-	-	-	-	-	-
HMKIHHLC_01518	3.67e-78	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
HMKIHHLC_01519	2.03e-22	-	-	-	-	-	-	-	-
HMKIHHLC_01521	7.95e-73	-	-	-	-	-	-	-	-
HMKIHHLC_01523	1.95e-158	-	-	-	S	-	-	-	DNA methylation
HMKIHHLC_01524	1.59e-26	-	-	-	-	-	-	-	-
HMKIHHLC_01525	5.56e-72	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HMKIHHLC_01527	1.9e-295	-	-	-	S	-	-	-	DNA helicase activity
HMKIHHLC_01528	1.1e-56	-	-	-	S	-	-	-	calcium ion binding
HMKIHHLC_01529	1.34e-273	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMKIHHLC_01530	7.18e-14	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMKIHHLC_01531	8.14e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HMKIHHLC_01532	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HMKIHHLC_01533	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMKIHHLC_01534	2.68e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01536	5.96e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HMKIHHLC_01537	4.31e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HMKIHHLC_01538	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HMKIHHLC_01539	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMKIHHLC_01540	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HMKIHHLC_01542	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMKIHHLC_01543	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HMKIHHLC_01544	1.11e-124	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HMKIHHLC_01545	5.67e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HMKIHHLC_01546	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HMKIHHLC_01547	1.16e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HMKIHHLC_01548	7.16e-257	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_01550	1.02e-20	-	-	-	-	-	-	-	-
HMKIHHLC_01551	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HMKIHHLC_01552	1.31e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HMKIHHLC_01553	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HMKIHHLC_01555	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HMKIHHLC_01556	1.01e-88	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HMKIHHLC_01557	2.02e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HMKIHHLC_01560	3.72e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HMKIHHLC_01561	8.14e-79	-	-	-	S	-	-	-	MucBP domain
HMKIHHLC_01562	9.76e-80	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01563	4.77e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_01564	3.16e-298	-	-	-	I	-	-	-	Acyltransferase family
HMKIHHLC_01565	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
HMKIHHLC_01566	4.25e-223	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
HMKIHHLC_01567	3.27e-187	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01568	4.07e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01569	1.49e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMKIHHLC_01570	8.29e-50	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HMKIHHLC_01571	1.56e-117	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMKIHHLC_01572	6.63e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMKIHHLC_01573	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HMKIHHLC_01574	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HMKIHHLC_01575	1.54e-190	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HMKIHHLC_01576	1.23e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HMKIHHLC_01577	2.69e-148	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMKIHHLC_01578	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HMKIHHLC_01579	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01580	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMKIHHLC_01581	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMKIHHLC_01582	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HMKIHHLC_01583	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HMKIHHLC_01585	4.74e-303	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HMKIHHLC_01586	4.32e-226	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMKIHHLC_01587	1.61e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HMKIHHLC_01588	6.64e-190	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMKIHHLC_01589	2.03e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HMKIHHLC_01590	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMKIHHLC_01591	1.06e-182	-	-	-	-	-	-	-	-
HMKIHHLC_01592	2.7e-192	-	-	-	-	-	-	-	-
HMKIHHLC_01593	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HMKIHHLC_01594	1.72e-140	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMKIHHLC_01595	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HMKIHHLC_01596	8.44e-70	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_01597	1.95e-296	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMKIHHLC_01598	9.47e-317	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMKIHHLC_01599	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HMKIHHLC_01600	9.29e-24	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMKIHHLC_01601	1.25e-46	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMKIHHLC_01602	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMKIHHLC_01603	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HMKIHHLC_01605	1.69e-140	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HMKIHHLC_01606	2.36e-162	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HMKIHHLC_01607	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HMKIHHLC_01608	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HMKIHHLC_01609	1.33e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMKIHHLC_01610	1.24e-58	-	-	-	G	-	-	-	MFS/sugar transport protein
HMKIHHLC_01611	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
HMKIHHLC_01612	1.71e-87	-	-	-	-	-	-	-	-
HMKIHHLC_01613	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01614	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HMKIHHLC_01615	2.17e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMKIHHLC_01618	4.36e-91	-	-	-	-	-	-	-	-
HMKIHHLC_01619	1.03e-99	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_01621	0.000177	-	-	-	G	-	-	-	Belongs to the peptidase S8 family
HMKIHHLC_01622	3.09e-56	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HMKIHHLC_01623	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
HMKIHHLC_01624	5.62e-180	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_01625	1.43e-85	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_01626	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMKIHHLC_01627	4.65e-134	-	-	-	-	-	-	-	-
HMKIHHLC_01628	8.28e-30	-	-	-	-	-	-	-	-
HMKIHHLC_01629	1.49e-84	-	-	-	-	-	-	-	-
HMKIHHLC_01630	4.54e-91	-	-	-	-	-	-	-	-
HMKIHHLC_01631	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMKIHHLC_01633	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HMKIHHLC_01634	3.35e-106	-	-	-	S	-	-	-	VanZ like family
HMKIHHLC_01635	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HMKIHHLC_01636	2.91e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HMKIHHLC_01637	6.41e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HMKIHHLC_01638	1.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMKIHHLC_01639	6.29e-191	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HMKIHHLC_01640	3.89e-210	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_01641	4.33e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMKIHHLC_01642	2.02e-99	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HMKIHHLC_01643	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HMKIHHLC_01644	1.06e-205	-	-	-	C	-	-	-	nadph quinone reductase
HMKIHHLC_01645	1.46e-137	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HMKIHHLC_01646	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HMKIHHLC_01648	3.5e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HMKIHHLC_01649	2.82e-280	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HMKIHHLC_01650	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HMKIHHLC_01651	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HMKIHHLC_01652	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMKIHHLC_01653	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HMKIHHLC_01654	4.49e-144	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMKIHHLC_01655	2.25e-156	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
HMKIHHLC_01656	3.69e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMKIHHLC_01657	8.74e-146	-	-	-	GM	-	-	-	NAD(P)H-binding
HMKIHHLC_01658	1.79e-71	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HMKIHHLC_01659	1.91e-102	yphH	-	-	S	-	-	-	Cupin domain
HMKIHHLC_01660	6.96e-206	-	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_01661	1.2e-57	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_01662	8.64e-57	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_01663	2.75e-216	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMKIHHLC_01664	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMKIHHLC_01665	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMKIHHLC_01666	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HMKIHHLC_01667	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMKIHHLC_01668	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HMKIHHLC_01669	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMKIHHLC_01670	8.29e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMKIHHLC_01671	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HMKIHHLC_01672	2.8e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMKIHHLC_01673	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HMKIHHLC_01674	2.3e-121	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01675	1.5e-37	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01677	3.45e-74	ps105	-	-	-	-	-	-	-
HMKIHHLC_01678	3.12e-196	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HMKIHHLC_01679	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HMKIHHLC_01680	5.38e-307	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_01681	1.3e-65	-	-	-	K	-	-	-	TRANSCRIPTIONal
HMKIHHLC_01682	5.01e-138	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HMKIHHLC_01683	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HMKIHHLC_01684	6.94e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HMKIHHLC_01685	1.22e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HMKIHHLC_01686	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
HMKIHHLC_01687	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMKIHHLC_01688	5.49e-261	yacL	-	-	S	-	-	-	domain protein
HMKIHHLC_01689	3.66e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01690	3.24e-162	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMKIHHLC_01691	7.61e-66	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMKIHHLC_01692	1.33e-178	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMKIHHLC_01693	2.72e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_01694	1.11e-107	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMKIHHLC_01695	1.4e-100	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMKIHHLC_01696	2.89e-100	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMKIHHLC_01697	6.32e-253	ysdE	-	-	P	-	-	-	Citrate transporter
HMKIHHLC_01698	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMKIHHLC_01699	4.35e-146	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HMKIHHLC_01700	1.24e-254	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HMKIHHLC_01701	1.29e-168	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMKIHHLC_01702	5.17e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HMKIHHLC_01703	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HMKIHHLC_01704	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMKIHHLC_01705	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMKIHHLC_01706	1.17e-286	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMKIHHLC_01707	8.85e-194	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMKIHHLC_01708	2.05e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMKIHHLC_01709	2.53e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMKIHHLC_01710	1.01e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
HMKIHHLC_01711	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HMKIHHLC_01712	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HMKIHHLC_01713	6.11e-111	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMKIHHLC_01714	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HMKIHHLC_01715	1.14e-194	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HMKIHHLC_01717	6.37e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HMKIHHLC_01718	2.76e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HMKIHHLC_01719	4.41e-289	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HMKIHHLC_01720	4.82e-95	mocA	-	-	S	-	-	-	Oxidoreductase
HMKIHHLC_01721	6.53e-105	mocA	-	-	S	-	-	-	Oxidoreductase
HMKIHHLC_01722	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HMKIHHLC_01723	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMKIHHLC_01724	2.31e-176	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMKIHHLC_01725	1.24e-39	-	-	-	-	-	-	-	-
HMKIHHLC_01727	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMKIHHLC_01728	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HMKIHHLC_01729	1.33e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
HMKIHHLC_01730	5.69e-315	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HMKIHHLC_01731	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMKIHHLC_01732	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMKIHHLC_01733	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMKIHHLC_01734	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
HMKIHHLC_01735	7.17e-87	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HMKIHHLC_01736	1.15e-232	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMKIHHLC_01737	1.13e-268	-	-	-	S	-	-	-	Sterol carrier protein domain
HMKIHHLC_01738	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMKIHHLC_01739	1.62e-151	-	-	-	S	-	-	-	repeat protein
HMKIHHLC_01740	4.69e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HMKIHHLC_01741	1.41e-74	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMKIHHLC_01742	1.48e-166	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMKIHHLC_01743	2.56e-207	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMKIHHLC_01744	1.15e-212	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01745	2.38e-226	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMKIHHLC_01747	3.12e-251	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HMKIHHLC_01748	1.91e-203	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HMKIHHLC_01749	2.06e-19	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_01750	1.49e-107	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_01751	2.3e-186	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HMKIHHLC_01752	2.27e-205	-	-	-	J	-	-	-	Methyltransferase domain
HMKIHHLC_01753	4.06e-118	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMKIHHLC_01754	4.24e-272	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMKIHHLC_01756	4.73e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
HMKIHHLC_01757	4.3e-233	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_01758	1.3e-157	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMKIHHLC_01759	3.36e-280	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_01760	2.11e-35	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_01761	9.43e-146	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HMKIHHLC_01762	3.22e-251	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HMKIHHLC_01763	3.25e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMKIHHLC_01764	1.41e-305	ynbB	-	-	P	-	-	-	aluminum resistance
HMKIHHLC_01765	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HMKIHHLC_01766	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HMKIHHLC_01767	4.66e-316	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMKIHHLC_01768	1.17e-115	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HMKIHHLC_01769	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKIHHLC_01770	6.75e-57	-	-	-	-	-	-	-	-
HMKIHHLC_01771	1.15e-104	-	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_01772	6.05e-209	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
HMKIHHLC_01773	1.61e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HMKIHHLC_01774	1.4e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HMKIHHLC_01775	4.5e-114	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMKIHHLC_01776	1.71e-196	fbpC	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	TOBE domain
HMKIHHLC_01777	8.21e-314	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_01778	1.39e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMKIHHLC_01779	1.63e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HMKIHHLC_01780	2.78e-85	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_01781	7.34e-85	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_01782	9.07e-61	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HMKIHHLC_01783	4.06e-123	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMKIHHLC_01784	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMKIHHLC_01785	9.5e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HMKIHHLC_01786	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMKIHHLC_01787	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HMKIHHLC_01788	4.99e-184	-	-	-	-	-	-	-	-
HMKIHHLC_01789	9.21e-110	-	-	-	M	-	-	-	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMKIHHLC_01790	1.02e-201	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HMKIHHLC_01791	9.99e-90	-	-	-	-	-	-	-	-
HMKIHHLC_01792	2.83e-92	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMKIHHLC_01794	2.98e-305	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_01795	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMKIHHLC_01796	1.74e-171	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HMKIHHLC_01798	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMKIHHLC_01799	5.02e-20	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMKIHHLC_01800	2.99e-156	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMKIHHLC_01801	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMKIHHLC_01802	2.1e-297	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMKIHHLC_01803	6.37e-104	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMKIHHLC_01804	2.04e-94	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HMKIHHLC_01805	4.89e-145	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HMKIHHLC_01806	1.36e-245	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HMKIHHLC_01807	8.02e-114	-	-	-	-	-	-	-	-
HMKIHHLC_01808	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMKIHHLC_01809	5.98e-150	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HMKIHHLC_01810	7.86e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMKIHHLC_01811	3.68e-107	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMKIHHLC_01812	1.03e-67	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMKIHHLC_01813	1.11e-32	-	-	-	-	-	-	-	-
HMKIHHLC_01814	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HMKIHHLC_01815	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMKIHHLC_01816	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HMKIHHLC_01817	8.08e-280	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMKIHHLC_01819	1.3e-219	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMKIHHLC_01820	1.38e-221	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMKIHHLC_01821	5.91e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HMKIHHLC_01822	5.66e-119	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HMKIHHLC_01823	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HMKIHHLC_01824	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMKIHHLC_01825	6.02e-150	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HMKIHHLC_01826	1.15e-228	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HMKIHHLC_01827	2.07e-117	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HMKIHHLC_01828	3.49e-121	-	-	-	K	-	-	-	Helix-turn-helix domain
HMKIHHLC_01830	2.64e-73	ps105	-	-	-	-	-	-	-
HMKIHHLC_01831	9.97e-119	yveA	-	-	Q	-	-	-	Isochorismatase family
HMKIHHLC_01832	1.76e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_01833	2.09e-61	-	-	-	S	-	-	-	AAA domain
HMKIHHLC_01834	2.07e-204	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMKIHHLC_01835	1.12e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HMKIHHLC_01836	1.05e-127	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HMKIHHLC_01837	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01838	3.99e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMKIHHLC_01839	2.39e-28	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMKIHHLC_01840	9.54e-117	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMKIHHLC_01843	1.27e-15	-	-	-	-	-	-	-	-
HMKIHHLC_01847	1.21e-182	-	-	-	S	-	-	-	CAAX protease self-immunity
HMKIHHLC_01849	5.62e-75	-	-	-	-	-	-	-	-
HMKIHHLC_01851	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HMKIHHLC_01852	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HMKIHHLC_01853	1.83e-87	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HMKIHHLC_01854	3.64e-167	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMKIHHLC_01855	5.28e-110	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMKIHHLC_01856	1.09e-227	-	-	-	-	-	-	-	-
HMKIHHLC_01857	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HMKIHHLC_01858	1.56e-13	-	-	-	-	-	-	-	-
HMKIHHLC_01859	2.09e-143	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HMKIHHLC_01860	9.94e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_01861	1.2e-186	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HMKIHHLC_01862	2.62e-189	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMKIHHLC_01863	1.58e-71	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01864	1.42e-128	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01865	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMKIHHLC_01866	1.73e-246	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMKIHHLC_01867	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMKIHHLC_01868	1.41e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMKIHHLC_01869	2.85e-52	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMKIHHLC_01870	5.66e-230	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMKIHHLC_01871	1.4e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMKIHHLC_01872	2.36e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HMKIHHLC_01873	2.53e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMKIHHLC_01874	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HMKIHHLC_01875	6.51e-69	-	-	-	S	-	-	-	MazG-like family
HMKIHHLC_01876	4.36e-154	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HMKIHHLC_01877	2.14e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HMKIHHLC_01878	1.92e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
HMKIHHLC_01879	2.84e-63	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HMKIHHLC_01880	2.17e-287	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HMKIHHLC_01881	6e-49	-	-	-	E	-	-	-	Alpha/beta hydrolase family
HMKIHHLC_01882	1.07e-96	-	-	-	E	-	-	-	Alpha/beta hydrolase family
HMKIHHLC_01883	9.92e-60	-	-	-	E	-	-	-	Alpha/beta hydrolase family
HMKIHHLC_01884	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HMKIHHLC_01885	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMKIHHLC_01886	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HMKIHHLC_01887	3.47e-210	-	-	-	GM	-	-	-	NmrA-like family
HMKIHHLC_01888	3.25e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HMKIHHLC_01889	1.33e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HMKIHHLC_01890	3.56e-193	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMKIHHLC_01892	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HMKIHHLC_01893	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMKIHHLC_01894	1.35e-129	-	-	-	-	-	-	-	-
HMKIHHLC_01895	4.3e-311	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HMKIHHLC_01896	2.37e-222	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HMKIHHLC_01897	3.37e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01898	2.78e-207	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMKIHHLC_01899	2.07e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01900	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HMKIHHLC_01901	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMKIHHLC_01902	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HMKIHHLC_01903	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMKIHHLC_01904	1.73e-140	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMKIHHLC_01905	4.4e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMKIHHLC_01906	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMKIHHLC_01907	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HMKIHHLC_01908	9.91e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMKIHHLC_01909	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HMKIHHLC_01910	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HMKIHHLC_01911	4.31e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMKIHHLC_01912	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMKIHHLC_01913	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_01914	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMKIHHLC_01915	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_01916	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HMKIHHLC_01917	7.26e-208	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HMKIHHLC_01918	8.86e-65	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_01919	5.39e-108	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_01920	1.59e-66	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMKIHHLC_01921	1.4e-224	yicL	-	-	EG	-	-	-	EamA-like transporter family
HMKIHHLC_01922	0.0	-	-	-	-	-	-	-	-
HMKIHHLC_01923	6.11e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01924	1.17e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HMKIHHLC_01925	8.69e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HMKIHHLC_01926	1.21e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HMKIHHLC_01927	3.28e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMKIHHLC_01928	3.24e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMKIHHLC_01929	1.42e-39	-	-	-	-	-	-	-	-
HMKIHHLC_01930	3.54e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HMKIHHLC_01931	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMKIHHLC_01932	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
HMKIHHLC_01933	1.63e-281	-	-	-	-	-	-	-	-
HMKIHHLC_01934	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
HMKIHHLC_01935	1.49e-187	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMKIHHLC_01936	1.62e-294	-	-	-	S	-	-	-	Membrane
HMKIHHLC_01937	2.57e-55	-	-	-	-	-	-	-	-
HMKIHHLC_01938	7.59e-202	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_01939	3.11e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMKIHHLC_01940	2.15e-260	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
HMKIHHLC_01941	9.65e-16	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HMKIHHLC_01942	5.03e-133	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HMKIHHLC_01943	5.4e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01944	1.44e-226	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HMKIHHLC_01945	9.22e-117	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMKIHHLC_01946	2.24e-49	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMKIHHLC_01947	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMKIHHLC_01948	2.1e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HMKIHHLC_01949	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HMKIHHLC_01950	5.97e-150	ampC	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_01951	1.34e-223	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HMKIHHLC_01952	4.47e-108	-	-	-	C	-	-	-	Flavodoxin
HMKIHHLC_01953	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMKIHHLC_01954	5.82e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HMKIHHLC_01955	1.54e-84	-	-	-	-	-	-	-	-
HMKIHHLC_01956	3.18e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HMKIHHLC_01957	2.72e-185	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMKIHHLC_01958	9.01e-243	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_01959	3.19e-45	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HMKIHHLC_01960	2.26e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01961	2.09e-167	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMKIHHLC_01962	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HMKIHHLC_01963	1.87e-185	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMKIHHLC_01964	1e-235	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMKIHHLC_01965	3.16e-193	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HMKIHHLC_01966	5.59e-47	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HMKIHHLC_01967	3.04e-282	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_01968	4.94e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HMKIHHLC_01969	1.4e-279	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMKIHHLC_01970	4.72e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HMKIHHLC_01971	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HMKIHHLC_01972	3.93e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_01973	1.04e-237	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_01974	2.57e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMKIHHLC_01975	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMKIHHLC_01976	5.53e-217	ybbR	-	-	S	-	-	-	YbbR-like protein
HMKIHHLC_01977	1.73e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMKIHHLC_01978	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HMKIHHLC_01979	3.03e-158	-	-	-	-	-	-	-	-
HMKIHHLC_01982	2.33e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HMKIHHLC_01983	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HMKIHHLC_01984	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HMKIHHLC_01985	5.68e-220	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_01986	7.63e-34	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_01987	1.16e-204	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMKIHHLC_01988	3.06e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMKIHHLC_01989	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HMKIHHLC_01990	1.1e-76	-	-	-	-	-	-	-	-
HMKIHHLC_01991	4.98e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HMKIHHLC_01992	1.18e-221	-	-	-	E	-	-	-	Amino acid permease
HMKIHHLC_01993	7e-47	-	-	-	-	-	-	-	-
HMKIHHLC_01994	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HMKIHHLC_01995	5.41e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMKIHHLC_01996	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMKIHHLC_01997	2.58e-274	yqiG	-	-	C	-	-	-	Oxidoreductase
HMKIHHLC_01998	2.03e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMKIHHLC_01999	1.14e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
HMKIHHLC_02000	6.03e-17	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
HMKIHHLC_02001	7.95e-06	-	-	-	S	-	-	-	SpoVT / AbrB like domain
HMKIHHLC_02002	5.31e-136	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMKIHHLC_02003	3.38e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HMKIHHLC_02004	2.03e-254	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMKIHHLC_02005	3.97e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMKIHHLC_02006	1.97e-134	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMKIHHLC_02007	1.75e-71	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMKIHHLC_02008	4.52e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMKIHHLC_02009	7.06e-117	-	-	-	-	-	-	-	-
HMKIHHLC_02010	3.55e-312	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
HMKIHHLC_02011	2.17e-161	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HMKIHHLC_02012	5.55e-139	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HMKIHHLC_02013	3.8e-224	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HMKIHHLC_02014	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HMKIHHLC_02015	8.58e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HMKIHHLC_02016	2.56e-270	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HMKIHHLC_02017	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMKIHHLC_02018	6.81e-120	ycaC	-	-	Q	-	-	-	Isochorismatase family
HMKIHHLC_02019	8.3e-123	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
HMKIHHLC_02020	0.0	ybeC	-	-	E	-	-	-	amino acid
HMKIHHLC_02022	1.09e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HMKIHHLC_02023	9.36e-34	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HMKIHHLC_02025	2.76e-217	-	-	-	M	-	-	-	LysM domain
HMKIHHLC_02026	2.91e-53	-	-	-	M	-	-	-	LysM domain
HMKIHHLC_02027	3.06e-07	-	-	-	-	-	-	-	-
HMKIHHLC_02028	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMKIHHLC_02029	4.53e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HMKIHHLC_02030	1.21e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_02031	1.05e-08	lysR	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_02032	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HMKIHHLC_02033	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HMKIHHLC_02034	8.85e-47	-	-	-	-	-	-	-	-
HMKIHHLC_02035	2.2e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMKIHHLC_02036	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMKIHHLC_02037	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMKIHHLC_02038	5.11e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMKIHHLC_02039	6.32e-202	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMKIHHLC_02040	2.32e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HMKIHHLC_02041	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMKIHHLC_02042	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMKIHHLC_02043	7.42e-253	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMKIHHLC_02044	3.36e-199	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HMKIHHLC_02045	1.94e-143	-	-	-	M	-	-	-	Acyltransferase family
HMKIHHLC_02046	3.4e-155	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HMKIHHLC_02047	1.4e-133	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HMKIHHLC_02048	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMKIHHLC_02049	6.96e-41	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMKIHHLC_02050	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMKIHHLC_02051	1.7e-187	-	-	-	-	-	-	-	-
HMKIHHLC_02053	1.25e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMKIHHLC_02054	2.61e-163	-	-	-	-	-	-	-	-
HMKIHHLC_02055	2.29e-87	-	-	-	-	-	-	-	-
HMKIHHLC_02056	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HMKIHHLC_02057	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HMKIHHLC_02058	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMKIHHLC_02059	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_02060	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMKIHHLC_02061	1.88e-47	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HMKIHHLC_02062	8.84e-154	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMKIHHLC_02063	8.78e-280	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMKIHHLC_02064	5.64e-173	ypaC	-	-	Q	-	-	-	Methyltransferase domain
HMKIHHLC_02065	0.0	-	-	-	S	-	-	-	ABC transporter
HMKIHHLC_02066	5.84e-224	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HMKIHHLC_02067	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMKIHHLC_02068	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMKIHHLC_02069	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMKIHHLC_02070	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HMKIHHLC_02071	1.45e-278	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HMKIHHLC_02072	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HMKIHHLC_02073	8.34e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HMKIHHLC_02074	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMKIHHLC_02075	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HMKIHHLC_02076	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HMKIHHLC_02077	4.65e-43	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HMKIHHLC_02078	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMKIHHLC_02079	1.14e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HMKIHHLC_02080	2.31e-179	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMKIHHLC_02081	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HMKIHHLC_02082	1.47e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HMKIHHLC_02083	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HMKIHHLC_02084	8.02e-107	-	-	-	F	-	-	-	NUDIX domain
HMKIHHLC_02085	2.02e-147	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMKIHHLC_02086	7.09e-11	-	-	-	-	-	-	-	-
HMKIHHLC_02088	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_02089	2.87e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_02091	3.77e-159	-	-	-	-	-	-	-	-
HMKIHHLC_02092	5.85e-297	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMKIHHLC_02093	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMKIHHLC_02094	4.11e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMKIHHLC_02095	2.85e-156	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_02096	4.16e-279	-	-	-	-	-	-	-	-
HMKIHHLC_02097	6e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMKIHHLC_02098	1.57e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HMKIHHLC_02099	5.36e-143	-	-	-	-	-	-	-	-
HMKIHHLC_02100	8.5e-91	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_02101	1.12e-116	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_02102	3.94e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_02103	1.55e-108	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
HMKIHHLC_02104	5.66e-193	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HMKIHHLC_02105	0.0	-	-	-	L	-	-	-	DNA helicase
HMKIHHLC_02106	3.66e-172	-	-	-	L	-	-	-	DNA helicase
HMKIHHLC_02108	1.08e-267	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_02110	1.91e-24	-	-	-	S	-	-	-	Short C-terminal domain
HMKIHHLC_02111	1.26e-170	-	-	-	S	-	-	-	sequence-specific DNA binding
HMKIHHLC_02112	2.87e-12	-	-	-	-	-	-	-	-
HMKIHHLC_02113	5.01e-09	-	-	-	S	-	-	-	Protein of unknown function, DUF536
HMKIHHLC_02115	3.07e-72	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_02118	1.62e-105	-	-	-	L	-	-	-	Transposase DDE domain
HMKIHHLC_02119	2.51e-115	-	-	-	S	-	-	-	AAA domain
HMKIHHLC_02120	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
HMKIHHLC_02121	6.98e-131	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_02122	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HMKIHHLC_02123	5.86e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_02124	8.04e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMKIHHLC_02126	1.21e-150	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_02127	7.51e-84	-	-	-	-	-	-	-	-
HMKIHHLC_02128	3.08e-127	-	-	-	D	-	-	-	Relaxase/Mobilisation nuclease domain
HMKIHHLC_02129	4.04e-22	mobC	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HMKIHHLC_02130	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
HMKIHHLC_02131	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
HMKIHHLC_02132	1.2e-144	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMKIHHLC_02133	2.85e-212	-	-	-	EG	-	-	-	EamA-like transporter family
HMKIHHLC_02134	6.71e-34	-	-	-	-	-	-	-	-
HMKIHHLC_02135	4.98e-112	-	-	-	-	-	-	-	-
HMKIHHLC_02136	6.98e-53	-	-	-	-	-	-	-	-
HMKIHHLC_02137	6.12e-239	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HMKIHHLC_02138	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_02139	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_02140	1.94e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMKIHHLC_02141	0.0	-	-	-	M	-	-	-	domain protein
HMKIHHLC_02142	8.09e-118	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HMKIHHLC_02143	1.28e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HMKIHHLC_02144	4.55e-212	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HMKIHHLC_02146	1.53e-19	-	-	-	-	-	-	-	-
HMKIHHLC_02147	3.11e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_02148	2.07e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMKIHHLC_02149	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMKIHHLC_02151	1.32e-51	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_02152	9.18e-137	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMKIHHLC_02153	5.6e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMKIHHLC_02154	1.44e-277	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_02155	1.65e-210	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HMKIHHLC_02157	1.98e-91	-	-	-	-	-	-	-	-
HMKIHHLC_02158	1.31e-266	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMKIHHLC_02159	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_02160	4.17e-117	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMKIHHLC_02161	1.73e-63	-	-	-	-	-	-	-	-
HMKIHHLC_02162	1.11e-95	-	-	-	-	-	-	-	-
HMKIHHLC_02163	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HMKIHHLC_02164	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMKIHHLC_02165	1.88e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HMKIHHLC_02166	2.05e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HMKIHHLC_02167	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HMKIHHLC_02168	1.36e-292	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMKIHHLC_02169	5.49e-71	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HMKIHHLC_02170	1.7e-84	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HMKIHHLC_02171	2.66e-117	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_02172	1.67e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMKIHHLC_02173	1.69e-273	-	-	-	K	-	-	-	Sigma-54 interaction domain
HMKIHHLC_02174	1.06e-293	-	-	-	K	-	-	-	Sigma-54 interaction domain
HMKIHHLC_02175	6.79e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HMKIHHLC_02176	2.07e-210	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HMKIHHLC_02177	4.56e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HMKIHHLC_02178	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMKIHHLC_02179	4.06e-169	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMKIHHLC_02180	5.31e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HMKIHHLC_02181	9.26e-186	inlJ	-	-	M	-	-	-	MucBP domain
HMKIHHLC_02182	6.02e-82	inlJ	-	-	M	-	-	-	MucBP domain
HMKIHHLC_02183	2.16e-167	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_02184	1.25e-306	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
HMKIHHLC_02185	8.67e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMKIHHLC_02186	1.06e-172	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMKIHHLC_02187	6.44e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMKIHHLC_02188	2.57e-129	-	-	-	S	-	-	-	EcsC protein family
HMKIHHLC_02189	0.000345	-	-	-	K	-	-	-	sequence-specific DNA binding
HMKIHHLC_02190	3.39e-104	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMKIHHLC_02191	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMKIHHLC_02192	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HMKIHHLC_02193	6.56e-187	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMKIHHLC_02194	1.12e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HMKIHHLC_02195	3.28e-54	-	-	-	-	-	-	-	-
HMKIHHLC_02197	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
HMKIHHLC_02198	8.73e-238	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMKIHHLC_02199	2.92e-257	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HMKIHHLC_02200	2.06e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HMKIHHLC_02201	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMKIHHLC_02202	2.19e-307	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HMKIHHLC_02203	9.15e-34	-	-	-	-	-	-	-	-
HMKIHHLC_02205	4.09e-72	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_02206	1.01e-45	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_02207	1.17e-224	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
HMKIHHLC_02208	6.91e-120	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
HMKIHHLC_02210	7.64e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMKIHHLC_02211	7.96e-20	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
HMKIHHLC_02212	1.13e-17	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMKIHHLC_02213	2.81e-201	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMKIHHLC_02214	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HMKIHHLC_02215	1.06e-29	-	-	-	-	-	-	-	-
HMKIHHLC_02216	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HMKIHHLC_02217	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMKIHHLC_02218	3.77e-160	-	-	-	T	-	-	-	Histidine kinase
HMKIHHLC_02219	1.76e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_02220	1.13e-193	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_02221	2.4e-170	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMKIHHLC_02222	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMKIHHLC_02223	1.12e-137	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HMKIHHLC_02224	9.05e-67	-	-	-	-	-	-	-	-
HMKIHHLC_02225	3.86e-68	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMKIHHLC_02226	6.04e-179	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMKIHHLC_02227	2.91e-148	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HMKIHHLC_02228	9.52e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HMKIHHLC_02229	2.09e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HMKIHHLC_02230	4.74e-59	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02231	2.11e-103	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HMKIHHLC_02233	5.68e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
HMKIHHLC_02234	2.56e-219	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HMKIHHLC_02235	3.35e-141	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HMKIHHLC_02236	2.48e-173	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMKIHHLC_02237	1.27e-248	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HMKIHHLC_02238	5.91e-198	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HMKIHHLC_02239	4.82e-220	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMKIHHLC_02240	1.4e-82	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HMKIHHLC_02241	9.53e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HMKIHHLC_02242	1.83e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMKIHHLC_02243	6.7e-192	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HMKIHHLC_02244	7.88e-147	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HMKIHHLC_02245	1.5e-44	-	-	-	-	-	-	-	-
HMKIHHLC_02246	8.64e-163	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_02247	8.34e-235	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMKIHHLC_02248	1.4e-207	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMKIHHLC_02249	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HMKIHHLC_02250	8.3e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HMKIHHLC_02251	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMKIHHLC_02252	1.06e-219	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HMKIHHLC_02253	9.16e-244	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMKIHHLC_02254	5.74e-89	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMKIHHLC_02255	1.05e-142	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMKIHHLC_02256	3.73e-126	-	-	-	-	-	-	-	-
HMKIHHLC_02257	7.66e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HMKIHHLC_02258	5.97e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HMKIHHLC_02260	3.25e-135	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMKIHHLC_02261	5.96e-198	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_02262	1.42e-237	-	-	-	S	-	-	-	EpsG family
HMKIHHLC_02263	9.46e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HMKIHHLC_02264	1.73e-36	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HMKIHHLC_02265	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMKIHHLC_02266	1.17e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMKIHHLC_02267	2.11e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HMKIHHLC_02268	7.92e-74	-	-	-	-	-	-	-	-
HMKIHHLC_02269	4.99e-72	-	-	-	-	-	-	-	-
HMKIHHLC_02270	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HMKIHHLC_02271	1.89e-216	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMKIHHLC_02272	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HMKIHHLC_02274	1.41e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HMKIHHLC_02275	7.23e-66	-	-	-	-	-	-	-	-
HMKIHHLC_02276	1.51e-169	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HMKIHHLC_02277	1.47e-148	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_02278	1.77e-249	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_02279	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_02282	1.09e-14	-	-	-	-	-	-	-	-
HMKIHHLC_02283	2.1e-27	-	-	-	-	-	-	-	-
HMKIHHLC_02284	5.98e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMKIHHLC_02285	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_02286	2.05e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HMKIHHLC_02287	3.94e-92	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_02288	6.51e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_02289	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HMKIHHLC_02290	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMKIHHLC_02291	4.18e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMKIHHLC_02292	1.92e-283	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HMKIHHLC_02293	2.13e-181	-	-	-	K	-	-	-	acetyltransferase
HMKIHHLC_02294	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMKIHHLC_02295	7.08e-224	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_02296	2.5e-32	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HMKIHHLC_02299	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
HMKIHHLC_02300	7.98e-155	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMKIHHLC_02301	2.19e-182	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HMKIHHLC_02302	1.8e-272	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HMKIHHLC_02304	6.29e-126	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HMKIHHLC_02305	5.34e-112	repA	-	-	S	-	-	-	Replication initiator protein A
HMKIHHLC_02307	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HMKIHHLC_02309	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMKIHHLC_02310	2.29e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMKIHHLC_02311	4.52e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMKIHHLC_02312	6.65e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMKIHHLC_02318	1.26e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMKIHHLC_02319	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HMKIHHLC_02320	4.71e-280	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMKIHHLC_02321	2.38e-205	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMKIHHLC_02322	2.68e-236	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMKIHHLC_02323	4.78e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
HMKIHHLC_02324	1.58e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HMKIHHLC_02325	3e-103	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HMKIHHLC_02326	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMKIHHLC_02327	8.56e-310	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HMKIHHLC_02328	3.74e-27	-	-	-	-	-	-	-	-
HMKIHHLC_02330	5.94e-214	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HMKIHHLC_02331	3.18e-31	-	-	-	-	-	-	-	-
HMKIHHLC_02332	1.4e-26	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HMKIHHLC_02333	4.07e-165	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMKIHHLC_02334	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMKIHHLC_02335	3.23e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMKIHHLC_02336	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HMKIHHLC_02337	2.31e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMKIHHLC_02338	5.42e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMKIHHLC_02339	5.03e-193	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMKIHHLC_02340	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMKIHHLC_02341	2.17e-106	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMKIHHLC_02342	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HMKIHHLC_02343	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HMKIHHLC_02344	2.35e-23	-	-	-	-	-	-	-	-
HMKIHHLC_02345	1.38e-28	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HMKIHHLC_02346	1.56e-141	-	-	-	S	-	-	-	Phage tail tube protein
HMKIHHLC_02347	5.12e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HMKIHHLC_02348	1.69e-83	-	-	-	S	-	-	-	exonuclease activity
HMKIHHLC_02349	3.2e-67	-	-	-	S	-	-	-	Phage head-tail joining protein
HMKIHHLC_02350	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HMKIHHLC_02351	4.22e-60	-	-	-	S	-	-	-	Thiamine-binding protein
HMKIHHLC_02352	1.73e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMKIHHLC_02353	4.49e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HMKIHHLC_02354	4.14e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMKIHHLC_02355	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HMKIHHLC_02356	7.13e-134	-	-	-	-	-	-	-	-
HMKIHHLC_02357	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_02358	1.23e-194	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMKIHHLC_02359	1.24e-124	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HMKIHHLC_02360	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMKIHHLC_02361	5.94e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMKIHHLC_02362	8.29e-174	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HMKIHHLC_02363	5.04e-147	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HMKIHHLC_02364	6.55e-57	-	-	-	-	-	-	-	-
HMKIHHLC_02365	1.25e-264	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HMKIHHLC_02366	1.57e-235	yveB	-	-	I	-	-	-	PAP2 superfamily
HMKIHHLC_02367	4.84e-203	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMKIHHLC_02368	1.04e-152	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HMKIHHLC_02369	1.48e-68	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
HMKIHHLC_02370	4.6e-189	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMKIHHLC_02371	1.27e-111	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMKIHHLC_02372	9.59e-294	cps1C	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMKIHHLC_02373	2.96e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_02374	2.04e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMKIHHLC_02375	2.43e-203	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HMKIHHLC_02376	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMKIHHLC_02377	2.25e-39	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
HMKIHHLC_02378	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMKIHHLC_02379	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMKIHHLC_02380	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_02381	7.01e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HMKIHHLC_02382	2.3e-224	-	-	-	S	-	-	-	peptidoglycan catabolic process
HMKIHHLC_02383	7.12e-43	-	-	-	-	-	-	-	-
HMKIHHLC_02385	8.17e-82	-	-	-	-	-	-	-	-
HMKIHHLC_02387	1.46e-86	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HMKIHHLC_02388	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMKIHHLC_02389	3.51e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HMKIHHLC_02390	5.82e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HMKIHHLC_02391	7.85e-106	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HMKIHHLC_02392	3.03e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HMKIHHLC_02393	1.06e-149	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HMKIHHLC_02394	1.32e-100	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HMKIHHLC_02395	3.15e-55	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HMKIHHLC_02397	1.04e-83	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HMKIHHLC_02398	1.93e-114	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HMKIHHLC_02400	1.01e-252	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_02401	4.62e-217	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HMKIHHLC_02403	3.4e-83	-	-	-	L	-	-	-	Transposase DDE domain
HMKIHHLC_02404	3.09e-90	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_02405	1.26e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_02408	4.15e-42	-	-	-	-	-	-	-	-
HMKIHHLC_02409	5.45e-26	-	-	-	-	-	-	-	-
HMKIHHLC_02410	1.33e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HMKIHHLC_02411	6.79e-55	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HMKIHHLC_02412	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HMKIHHLC_02413	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HMKIHHLC_02414	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HMKIHHLC_02415	9.42e-123	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMKIHHLC_02416	1.71e-215	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HMKIHHLC_02417	3.3e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMKIHHLC_02420	9.43e-228	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
HMKIHHLC_02421	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HMKIHHLC_02422	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
HMKIHHLC_02423	1.65e-213	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HMKIHHLC_02424	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HMKIHHLC_02425	3.17e-144	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMKIHHLC_02426	1.65e-63	-	-	-	-	-	-	-	-
HMKIHHLC_02427	1.03e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMKIHHLC_02428	2.29e-125	-	-	-	K	-	-	-	transcriptional regulator
HMKIHHLC_02429	4.84e-278	-	-	-	V	-	-	-	Beta-lactamase
HMKIHHLC_02430	7.03e-130	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02431	3.94e-154	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HMKIHHLC_02432	2.22e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HMKIHHLC_02433	1.54e-54	-	-	-	-	-	-	-	-
HMKIHHLC_02434	6.78e-297	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_02435	9.84e-81	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HMKIHHLC_02436	4.02e-168	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
HMKIHHLC_02441	1.8e-69	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_02443	4.63e-127	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HMKIHHLC_02444	4.86e-208	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HMKIHHLC_02445	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HMKIHHLC_02446	1.87e-191	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HMKIHHLC_02447	6.02e-203	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMKIHHLC_02448	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HMKIHHLC_02450	8.62e-182	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMKIHHLC_02451	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HMKIHHLC_02452	3.17e-51	-	-	-	-	-	-	-	-
HMKIHHLC_02454	5.76e-228	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HMKIHHLC_02455	1.82e-129	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HMKIHHLC_02456	2.32e-169	-	-	-	-	-	-	-	-
HMKIHHLC_02457	3.59e-127	-	-	-	D	-	-	-	AAA domain
HMKIHHLC_02459	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_02460	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMKIHHLC_02462	1.62e-232	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HMKIHHLC_02463	7.89e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HMKIHHLC_02473	6.1e-27	-	-	-	-	-	-	-	-
HMKIHHLC_02474	2.45e-64	-	-	-	-	-	-	-	-
HMKIHHLC_02475	1.79e-59	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_02476	3.56e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMKIHHLC_02478	2.93e-175	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
HMKIHHLC_02479	4.18e-262	-	-	-	-	-	-	-	-
HMKIHHLC_02480	4.07e-296	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HMKIHHLC_02481	1.01e-222	-	-	-	G	-	-	-	MFS/sugar transport protein
HMKIHHLC_02482	1.03e-37	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HMKIHHLC_02483	4.77e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_02484	1.35e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HMKIHHLC_02485	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMKIHHLC_02486	6.85e-107	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMKIHHLC_02487	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HMKIHHLC_02488	6.08e-97	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMKIHHLC_02489	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMKIHHLC_02490	9.64e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMKIHHLC_02491	1.47e-48	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02492	2.54e-193	-	-	-	T	-	-	-	GHKL domain
HMKIHHLC_02493	9.29e-157	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMKIHHLC_02496	6.36e-173	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HMKIHHLC_02498	1.58e-91	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMKIHHLC_02499	2.14e-69	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMKIHHLC_02500	2.25e-157	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_02501	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_02502	8.01e-131	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMKIHHLC_02503	2.15e-199	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMKIHHLC_02504	4.22e-70	-	-	-	-	-	-	-	-
HMKIHHLC_02507	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMKIHHLC_02508	5e-27	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HMKIHHLC_02509	1.55e-25	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HMKIHHLC_02510	1.13e-79	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HMKIHHLC_02511	0.0	ycaM	-	-	E	-	-	-	amino acid
HMKIHHLC_02512	8.79e-93	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HMKIHHLC_02514	3.07e-56	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HMKIHHLC_02515	1.78e-48	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
HMKIHHLC_02516	3.8e-50	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_02517	3.29e-101	fucA	4.1.2.17, 5.1.3.4	-	G	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
HMKIHHLC_02518	7.17e-216	-	-	-	S	-	-	-	Putative esterase
HMKIHHLC_02519	1.56e-170	-	-	-	-	-	-	-	-
HMKIHHLC_02520	8.47e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMKIHHLC_02522	9.32e-131	-	-	-	Q	-	-	-	methyltransferase
HMKIHHLC_02523	6.95e-78	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HMKIHHLC_02524	6.65e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HMKIHHLC_02525	1.19e-164	-	-	-	S	-	-	-	DJ-1/PfpI family
HMKIHHLC_02526	2.12e-70	-	-	-	K	-	-	-	Transcriptional
HMKIHHLC_02527	7.53e-49	-	-	-	-	-	-	-	-
HMKIHHLC_02528	1.05e-56	-	-	-	V	-	-	-	ABC transporter transmembrane region
HMKIHHLC_02529	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMKIHHLC_02530	1.65e-72	-	-	-	-	-	-	-	-
HMKIHHLC_02531	4.24e-117	-	-	-	-	-	-	-	-
HMKIHHLC_02532	5.61e-260	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
HMKIHHLC_02533	1.18e-149	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMKIHHLC_02535	7.91e-70	-	-	-	-	-	-	-	-
HMKIHHLC_02536	2.6e-232	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMKIHHLC_02537	1.4e-233	-	-	-	GK	-	-	-	helix_turn_helix, arabinose operon control protein
HMKIHHLC_02538	2.34e-155	-	-	-	S	-	-	-	-acetyltransferase
HMKIHHLC_02539	1.6e-119	yfbM	-	-	K	-	-	-	FR47-like protein
HMKIHHLC_02540	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HMKIHHLC_02541	1.76e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMKIHHLC_02542	2.8e-144	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMKIHHLC_02543	1.75e-71	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMKIHHLC_02544	4.09e-131	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_02545	1.76e-202	-	-	-	T	-	-	-	GHKL domain
HMKIHHLC_02546	1.01e-98	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMKIHHLC_02547	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HMKIHHLC_02548	1.05e-229	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_02549	6.94e-41	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMKIHHLC_02550	1.12e-77	-	-	-	N	-	-	-	domain, Protein
HMKIHHLC_02551	1.48e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMKIHHLC_02552	4.23e-141	-	-	-	S	-	-	-	Flavodoxin-like fold
HMKIHHLC_02553	1.45e-264	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMKIHHLC_02554	7.5e-132	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HMKIHHLC_02555	1.01e-139	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HMKIHHLC_02556	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HMKIHHLC_02560	2.2e-215	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMKIHHLC_02561	1.77e-248	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HMKIHHLC_02562	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMKIHHLC_02564	1.51e-124	-	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
HMKIHHLC_02565	1.12e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMKIHHLC_02566	6.07e-21	-	-	-	-	-	-	-	-
HMKIHHLC_02567	7.01e-40	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMKIHHLC_02568	8.74e-236	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMKIHHLC_02586	5e-305	-	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMKIHHLC_02587	1.02e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMKIHHLC_02588	4.62e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMKIHHLC_02589	1.52e-57	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMKIHHLC_02592	2.33e-118	gatY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HMKIHHLC_02594	1.19e-105	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
HMKIHHLC_02595	1.79e-245	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02596	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HMKIHHLC_02597	2.16e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMKIHHLC_02598	4.16e-148	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_02599	2.65e-173	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMKIHHLC_02600	2.83e-214	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HMKIHHLC_02601	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMKIHHLC_02605	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMKIHHLC_02606	9.42e-28	-	-	-	-	-	-	-	-
HMKIHHLC_02607	2.84e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HMKIHHLC_02608	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HMKIHHLC_02610	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HMKIHHLC_02611	1.7e-242	ysdE	-	-	P	-	-	-	Citrate transporter
HMKIHHLC_02612	6.31e-149	-	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	Mannitol dehydrogenase C-terminal domain
HMKIHHLC_02614	1.36e-257	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMKIHHLC_02615	1.28e-96	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HMKIHHLC_02619	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HMKIHHLC_02620	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMKIHHLC_02621	3.08e-162	-	-	-	S	-	-	-	Putative transposase
HMKIHHLC_02622	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HMKIHHLC_02623	9.09e-154	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMKIHHLC_02624	3.74e-107	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HMKIHHLC_02625	2.53e-78	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HMKIHHLC_02626	6.21e-23	-	-	-	-	-	-	-	-
HMKIHHLC_02628	4.14e-159	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMKIHHLC_02629	1e-129	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
HMKIHHLC_02630	2.77e-217	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMKIHHLC_02631	9.45e-127	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMKIHHLC_02632	1.16e-303	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HMKIHHLC_02634	5.09e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMKIHHLC_02635	1.99e-202	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HMKIHHLC_02636	2.27e-177	mprF	2.3.2.3	-	M	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	lysyltransferase activity
HMKIHHLC_02638	1.02e-107	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HMKIHHLC_02639	3.4e-37	-	-	-	-	-	-	-	-
HMKIHHLC_02640	1.02e-230	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HMKIHHLC_02641	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMKIHHLC_02642	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HMKIHHLC_02643	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMKIHHLC_02644	7.1e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HMKIHHLC_02646	1.65e-52	-	-	-	-	-	-	-	-
HMKIHHLC_02647	6.78e-82	-	-	-	-	-	-	-	-
HMKIHHLC_02648	2.39e-98	-	-	-	L	-	-	-	Initiator Replication protein
HMKIHHLC_02649	1.59e-235	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_02650	2.1e-161	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
HMKIHHLC_02651	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
HMKIHHLC_02652	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HMKIHHLC_02653	2.54e-111	-	-	-	-	-	-	-	-
HMKIHHLC_02654	4.83e-52	-	-	-	-	-	-	-	-
HMKIHHLC_02656	6.24e-244	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMKIHHLC_02657	1.25e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HMKIHHLC_02658	2.31e-190	-	-	-	K	-	-	-	Helix-turn-helix
HMKIHHLC_02661	1.43e-40	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
HMKIHHLC_02662	2.39e-109	-	-	-	-	-	-	-	-
HMKIHHLC_02665	5.16e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HMKIHHLC_02666	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HMKIHHLC_02667	1.15e-178	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HMKIHHLC_02668	7.43e-169	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HMKIHHLC_02669	3.66e-65	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HMKIHHLC_02670	1.56e-190	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMKIHHLC_02671	1.35e-68	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
HMKIHHLC_02673	9.67e-53	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HMKIHHLC_02674	1.65e-203	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
HMKIHHLC_02675	6.31e-236	-	-	-	-	-	-	-	-
HMKIHHLC_02676	1.53e-179	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HMKIHHLC_02677	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
HMKIHHLC_02679	2.11e-25	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKIHHLC_02680	6.67e-130	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMKIHHLC_02681	1.47e-103	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HMKIHHLC_02682	7.04e-106	wcaA	-	-	M	-	-	-	Glycosyl transferase family 2
HMKIHHLC_02683	1.53e-138	-	-	-	G	-	-	-	phosphotransferase system
HMKIHHLC_02684	2.2e-61	-	-	-	G	-	-	-	phosphotransferase system
HMKIHHLC_02685	1e-96	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMKIHHLC_02686	8.89e-23	-	-	-	M	-	-	-	SIS domain
HMKIHHLC_02687	1.96e-40	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HMKIHHLC_02688	4.23e-73	-	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HMKIHHLC_02689	8.85e-76	-	-	-	-	-	-	-	-
HMKIHHLC_02690	2.7e-139	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02692	1.89e-40	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HMKIHHLC_02693	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HMKIHHLC_02694	2.58e-37	-	-	-	-	-	-	-	-
HMKIHHLC_02695	1.38e-218	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMKIHHLC_02696	2.26e-146	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HMKIHHLC_02697	1.22e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HMKIHHLC_02699	2.36e-96	-	-	-	-	-	-	-	-
HMKIHHLC_02700	1.44e-74	-	-	-	-	-	-	-	-
HMKIHHLC_02701	1.52e-252	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HMKIHHLC_02702	2.16e-74	-	-	-	M	-	-	-	Right handed beta helix region
HMKIHHLC_02703	1.35e-67	-	-	-	M	-	-	-	group 2 family protein
HMKIHHLC_02704	1.46e-57	-	-	-	E	-	-	-	Hexapeptide repeat of succinyl-transferase
HMKIHHLC_02705	1.36e-95	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HMKIHHLC_02706	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMKIHHLC_02707	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMKIHHLC_02708	5.55e-173	-	-	-	M	-	-	-	Sulfatase
HMKIHHLC_02709	1.41e-70	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMKIHHLC_02710	5.43e-22	-	-	-	-	-	-	-	-
HMKIHHLC_02711	7.2e-173	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
HMKIHHLC_02713	2.35e-114	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMKIHHLC_02714	3.01e-94	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HMKIHHLC_02715	3.77e-186	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMKIHHLC_02718	8.18e-114	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HMKIHHLC_02719	1.34e-147	-	-	-	L	-	-	-	Resolvase, N terminal domain
HMKIHHLC_02720	9.06e-60	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
HMKIHHLC_02721	2.29e-122	-	-	-	K	-	-	-	Helix-turn-helix
HMKIHHLC_02723	8.84e-136	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HMKIHHLC_02725	0.000264	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HMKIHHLC_02726	4.19e-108	-	-	-	L	-	-	-	DNA methylase
HMKIHHLC_02727	1.69e-12	-	-	-	S	-	-	-	TcpE family
HMKIHHLC_02728	1.66e-116	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HMKIHHLC_02729	2.89e-102	-	-	-	-	-	-	-	-
HMKIHHLC_02730	1.29e-175	-	-	-	-	-	-	-	-
HMKIHHLC_02731	4.28e-93	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HMKIHHLC_02732	2.63e-205	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HMKIHHLC_02733	1.72e-103	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMKIHHLC_02734	1.49e-208	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMKIHHLC_02735	2.62e-09	-	-	-	S	-	-	-	Putative Holin-like Toxin (Hol-Tox)
HMKIHHLC_02736	4.87e-138	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
HMKIHHLC_02737	1.4e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMKIHHLC_02738	1.48e-195	-	-	-	C	-	-	-	nadph quinone reductase
HMKIHHLC_02739	9.99e-86	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HMKIHHLC_02740	3.74e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMKIHHLC_02741	1.9e-165	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HMKIHHLC_02742	8.87e-45	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HMKIHHLC_02743	1.25e-68	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMKIHHLC_02745	3.36e-163	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
HMKIHHLC_02748	6.79e-39	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HMKIHHLC_02749	5.23e-36	-	-	-	-	-	-	-	-
HMKIHHLC_02750	3.77e-92	-	-	-	K	-	-	-	Transcriptional regulator
HMKIHHLC_02751	1.92e-177	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HMKIHHLC_02753	4.17e-143	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HMKIHHLC_02754	1.54e-35	-	-	-	M	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMKIHHLC_02755	1.12e-79	-	-	-	S	-	-	-	phage tail tape measure protein
HMKIHHLC_02757	9.73e-109	-	-	-	-	-	-	-	-
HMKIHHLC_02758	3.28e-122	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
HMKIHHLC_02759	1.89e-121	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
HMKIHHLC_02760	1.35e-76	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMKIHHLC_02761	8.88e-109	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMKIHHLC_02762	3.77e-49	-	-	-	K	-	-	-	M protein trans-acting positive regulator
HMKIHHLC_02763	1.54e-54	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HMKIHHLC_02764	7.61e-116	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMKIHHLC_02765	7.93e-54	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HMKIHHLC_02768	6.34e-127	-	-	-	P	-	-	-	Belongs to the Dps family
HMKIHHLC_02769	9.72e-22	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HMKIHHLC_02770	7.76e-64	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMKIHHLC_02778	6.81e-93	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HMKIHHLC_02780	3.44e-110	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
HMKIHHLC_02781	2.15e-138	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
HMKIHHLC_02782	2.34e-51	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
HMKIHHLC_02783	5.74e-75	-	-	-	S	-	-	-	CAAX protease self-immunity
HMKIHHLC_02784	1.14e-148	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMKIHHLC_02785	6.57e-146	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HMKIHHLC_02786	2.49e-130	-	-	-	S	-	-	-	PglZ domain
HMKIHHLC_02788	4.73e-31	-	-	-	-	-	-	-	-
HMKIHHLC_02789	5.56e-85	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HMKIHHLC_02790	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMKIHHLC_02793	1.77e-69	-	-	-	L	-	-	-	Transposase DDE domain
HMKIHHLC_02794	6.82e-104	-	-	-	-	-	-	-	-
HMKIHHLC_02795	4.6e-82	-	-	-	-	-	-	-	-
HMKIHHLC_02796	1.34e-33	-	-	-	-	-	-	-	-
HMKIHHLC_02797	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HMKIHHLC_02798	2.89e-67	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMKIHHLC_02799	2.47e-81	-	-	-	G	-	-	-	COG0662 Mannose-6-phosphate isomerase
HMKIHHLC_02800	5.16e-74	-	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HMKIHHLC_02801	8.01e-52	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMKIHHLC_02803	9.46e-88	-	-	-	-	-	-	-	-
HMKIHHLC_02805	1.75e-44	repA	-	-	S	-	-	-	Replication initiator protein A
HMKIHHLC_02806	2.42e-54	-	-	-	-	-	-	-	-
HMKIHHLC_02808	6.17e-65	-	-	-	M	-	-	-	Cna protein B-type domain
HMKIHHLC_02809	1.51e-73	-	-	-	-	-	-	-	-