ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HKFIIIAO_00001 8.95e-315 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKFIIIAO_00002 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKFIIIAO_00003 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HKFIIIAO_00004 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKFIIIAO_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKFIIIAO_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKFIIIAO_00007 1.71e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HKFIIIAO_00008 1.59e-95 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKFIIIAO_00009 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKFIIIAO_00010 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HKFIIIAO_00011 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKFIIIAO_00012 3.43e-314 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HKFIIIAO_00013 4.96e-289 yttB - - EGP - - - Major Facilitator
HKFIIIAO_00014 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKFIIIAO_00015 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKFIIIAO_00017 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00018 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKFIIIAO_00019 5.02e-277 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKFIIIAO_00020 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HKFIIIAO_00021 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKFIIIAO_00022 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKFIIIAO_00023 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKFIIIAO_00025 2.4e-183 - - - S - - - haloacid dehalogenase-like hydrolase
HKFIIIAO_00026 4.47e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HKFIIIAO_00027 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HKFIIIAO_00028 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HKFIIIAO_00029 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
HKFIIIAO_00030 2.54e-50 - - - - - - - -
HKFIIIAO_00031 9.96e-291 sip - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_00032 1.1e-06 - - - K ko:K07727 - ko00000,ko03000 transcriptional regulator
HKFIIIAO_00034 3.96e-13 - - - - - - - -
HKFIIIAO_00035 4.71e-47 - - - - - - - -
HKFIIIAO_00036 2.04e-183 - - - L - - - DNA replication protein
HKFIIIAO_00037 2.03e-64 - - - S - - - Phage plasmid primase P4 family
HKFIIIAO_00039 3.49e-32 - - - - - - - -
HKFIIIAO_00040 3e-67 - - - S - - - Head-tail joining protein
HKFIIIAO_00041 1.28e-89 - - - L - - - HNH endonuclease
HKFIIIAO_00042 2.22e-108 - - - L - - - overlaps another CDS with the same product name
HKFIIIAO_00043 0.0 terL - - S - - - overlaps another CDS with the same product name
HKFIIIAO_00044 0.000703 - - - - - - - -
HKFIIIAO_00045 1.06e-260 - - - S - - - Phage portal protein
HKFIIIAO_00046 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HKFIIIAO_00047 3.39e-55 - - - S - - - Phage gp6-like head-tail connector protein
HKFIIIAO_00048 3.94e-77 - - - - - - - -
HKFIIIAO_00049 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKFIIIAO_00050 7.45e-53 - - - - - - - -
HKFIIIAO_00052 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HKFIIIAO_00053 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKFIIIAO_00054 3.55e-313 yycH - - S - - - YycH protein
HKFIIIAO_00055 3.54e-195 yycI - - S - - - YycH protein
HKFIIIAO_00056 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HKFIIIAO_00057 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HKFIIIAO_00058 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKFIIIAO_00059 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00060 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
HKFIIIAO_00061 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKFIIIAO_00062 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
HKFIIIAO_00063 1.34e-153 pnb - - C - - - nitroreductase
HKFIIIAO_00064 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HKFIIIAO_00065 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
HKFIIIAO_00066 0.0 - - - C - - - FMN_bind
HKFIIIAO_00067 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HKFIIIAO_00068 1.46e-204 - - - K - - - LysR family
HKFIIIAO_00069 2.49e-95 - - - C - - - FMN binding
HKFIIIAO_00070 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKFIIIAO_00071 1.66e-210 - - - S - - - KR domain
HKFIIIAO_00072 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HKFIIIAO_00073 5.07e-157 ydgI - - C - - - Nitroreductase family
HKFIIIAO_00074 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HKFIIIAO_00075 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HKFIIIAO_00076 1.27e-247 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKFIIIAO_00077 0.0 - - - S - - - Putative threonine/serine exporter
HKFIIIAO_00078 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKFIIIAO_00079 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HKFIIIAO_00080 1.36e-105 - - - S - - - ASCH
HKFIIIAO_00081 4.35e-165 - - - F - - - glutamine amidotransferase
HKFIIIAO_00082 1.67e-220 - - - K - - - WYL domain
HKFIIIAO_00083 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKFIIIAO_00084 0.0 fusA1 - - J - - - elongation factor G
HKFIIIAO_00085 7.44e-51 - - - S - - - Protein of unknown function
HKFIIIAO_00086 2.84e-81 - - - S - - - Protein of unknown function
HKFIIIAO_00087 4.28e-195 - - - EG - - - EamA-like transporter family
HKFIIIAO_00088 7.65e-121 yfbM - - K - - - FR47-like protein
HKFIIIAO_00089 1.4e-162 - - - S - - - DJ-1/PfpI family
HKFIIIAO_00090 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HKFIIIAO_00091 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_00092 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HKFIIIAO_00093 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00094 3.01e-213 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HKFIIIAO_00095 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HKFIIIAO_00096 2.38e-99 - - - - - - - -
HKFIIIAO_00097 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HKFIIIAO_00098 2.4e-180 - - - - - - - -
HKFIIIAO_00099 4.07e-05 - - - - - - - -
HKFIIIAO_00100 5.66e-184 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKFIIIAO_00101 1.67e-54 - - - - - - - -
HKFIIIAO_00102 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_00103 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HKFIIIAO_00104 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HKFIIIAO_00105 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
HKFIIIAO_00106 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HKFIIIAO_00107 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
HKFIIIAO_00108 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKFIIIAO_00109 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
HKFIIIAO_00110 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_00111 5.24e-193 larE - - S ko:K06864 - ko00000 NAD synthase
HKFIIIAO_00112 1.23e-227 - - - C - - - Zinc-binding dehydrogenase
HKFIIIAO_00113 9.25e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKFIIIAO_00114 1.18e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HKFIIIAO_00115 1.48e-140 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKFIIIAO_00116 4.15e-261 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HKFIIIAO_00117 3.4e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HKFIIIAO_00118 0.0 - - - L - - - HIRAN domain
HKFIIIAO_00119 5.04e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HKFIIIAO_00120 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HKFIIIAO_00121 1.27e-159 - - - - - - - -
HKFIIIAO_00122 4.17e-191 - - - I - - - Alpha/beta hydrolase family
HKFIIIAO_00123 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKFIIIAO_00124 1.23e-199 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKFIIIAO_00125 5.67e-64 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKFIIIAO_00126 9.93e-127 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HKFIIIAO_00127 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKFIIIAO_00128 5.46e-183 - - - F - - - Phosphorylase superfamily
HKFIIIAO_00129 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HKFIIIAO_00130 1.72e-142 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HKFIIIAO_00131 2.11e-97 - - - K - - - Transcriptional regulator
HKFIIIAO_00132 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKFIIIAO_00133 5.51e-106 - - - S - - - Protein of unknown function (DUF3021)
HKFIIIAO_00134 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HKFIIIAO_00135 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_00136 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HKFIIIAO_00138 2.16e-204 morA - - S - - - reductase
HKFIIIAO_00139 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HKFIIIAO_00140 1.92e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HKFIIIAO_00141 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HKFIIIAO_00142 4.29e-102 - - - - - - - -
HKFIIIAO_00143 0.0 - - - - - - - -
HKFIIIAO_00144 6.49e-268 - - - C - - - Oxidoreductase
HKFIIIAO_00145 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HKFIIIAO_00146 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_00147 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HKFIIIAO_00149 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HKFIIIAO_00150 1.64e-70 - - - K - - - Transcriptional regulator PadR-like family
HKFIIIAO_00151 6.08e-180 - - - - - - - -
HKFIIIAO_00152 1.57e-191 - - - - - - - -
HKFIIIAO_00153 3.37e-115 - - - - - - - -
HKFIIIAO_00154 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HKFIIIAO_00155 6.03e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_00156 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HKFIIIAO_00157 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HKFIIIAO_00158 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HKFIIIAO_00159 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
HKFIIIAO_00161 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00162 9.56e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HKFIIIAO_00163 1.58e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HKFIIIAO_00164 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HKFIIIAO_00165 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HKFIIIAO_00166 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_00167 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HKFIIIAO_00168 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HKFIIIAO_00169 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HKFIIIAO_00170 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKFIIIAO_00171 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_00172 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00173 2.91e-190 malA - - S - - - maltodextrose utilization protein MalA
HKFIIIAO_00174 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HKFIIIAO_00175 9.95e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKFIIIAO_00176 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HKFIIIAO_00177 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HKFIIIAO_00178 9.17e-52 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HKFIIIAO_00179 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HKFIIIAO_00180 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKFIIIAO_00181 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKFIIIAO_00182 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HKFIIIAO_00183 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HKFIIIAO_00184 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKFIIIAO_00185 1.92e-209 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HKFIIIAO_00186 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HKFIIIAO_00187 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKFIIIAO_00188 2.22e-207 mleR - - K - - - LysR substrate binding domain
HKFIIIAO_00189 0.0 - - - M - - - domain protein
HKFIIIAO_00191 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HKFIIIAO_00192 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00193 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00194 7.83e-38 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00195 1.31e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKFIIIAO_00196 1.19e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFIIIAO_00197 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKFIIIAO_00198 1.11e-146 pgm1 - - G - - - phosphoglycerate mutase
HKFIIIAO_00199 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HKFIIIAO_00200 6.33e-46 - - - - - - - -
HKFIIIAO_00201 1.35e-78 - - - S - - - Domain of unknown function (DU1801)
HKFIIIAO_00202 4.56e-210 fbpA - - K - - - Domain of unknown function (DUF814)
HKFIIIAO_00203 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKFIIIAO_00204 3.81e-18 - - - - - - - -
HKFIIIAO_00205 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFIIIAO_00206 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKFIIIAO_00207 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_00208 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HKFIIIAO_00209 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKFIIIAO_00210 4.77e-130 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00211 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HKFIIIAO_00212 5.3e-202 dkgB - - S - - - reductase
HKFIIIAO_00213 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKFIIIAO_00214 1.2e-91 - - - - - - - -
HKFIIIAO_00215 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
HKFIIIAO_00216 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKFIIIAO_00218 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKFIIIAO_00219 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKFIIIAO_00220 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HKFIIIAO_00221 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_00222 2.61e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HKFIIIAO_00223 1.21e-111 - - - - - - - -
HKFIIIAO_00224 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKFIIIAO_00225 4.17e-67 - - - - - - - -
HKFIIIAO_00226 7.09e-125 - - - - - - - -
HKFIIIAO_00227 1e-88 - - - - - - - -
HKFIIIAO_00228 8.08e-105 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HKFIIIAO_00229 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HKFIIIAO_00230 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HKFIIIAO_00231 2.2e-158 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HKFIIIAO_00232 2.75e-289 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_00233 3.56e-52 - - - - - - - -
HKFIIIAO_00234 1.86e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HKFIIIAO_00235 2.94e-261 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
HKFIIIAO_00236 4.64e-255 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HKFIIIAO_00237 5.81e-165 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HKFIIIAO_00238 9.18e-242 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HKFIIIAO_00239 6.1e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HKFIIIAO_00240 2.25e-265 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HKFIIIAO_00241 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HKFIIIAO_00242 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HKFIIIAO_00243 3.65e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HKFIIIAO_00244 6.09e-243 - - - S - - - Bacterial membrane protein, YfhO
HKFIIIAO_00245 2.39e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HKFIIIAO_00246 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKFIIIAO_00247 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKFIIIAO_00248 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HKFIIIAO_00249 2.6e-185 - - - - - - - -
HKFIIIAO_00250 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
HKFIIIAO_00251 1.95e-294 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
HKFIIIAO_00252 0.0 tagB 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycerophosphotransferase
HKFIIIAO_00253 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKFIIIAO_00254 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKFIIIAO_00255 9.53e-93 - - - - - - - -
HKFIIIAO_00256 8.9e-96 ywnA - - K - - - Transcriptional regulator
HKFIIIAO_00257 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00258 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKFIIIAO_00259 1.15e-152 - - - - - - - -
HKFIIIAO_00260 2.92e-57 - - - - - - - -
HKFIIIAO_00261 1.55e-55 - - - - - - - -
HKFIIIAO_00262 0.0 ydiC - - EGP - - - Major Facilitator
HKFIIIAO_00263 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_00264 2.83e-108 hpk2 - - T - - - Histidine kinase
HKFIIIAO_00265 2.78e-142 hpk2 - - T - - - Histidine kinase
HKFIIIAO_00266 1.33e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HKFIIIAO_00267 2.42e-65 - - - - - - - -
HKFIIIAO_00268 3.25e-166 yidA - - K - - - Helix-turn-helix domain, rpiR family
HKFIIIAO_00269 2.79e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_00270 3.35e-75 - - - - - - - -
HKFIIIAO_00271 2.87e-56 - - - - - - - -
HKFIIIAO_00272 2.92e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKFIIIAO_00273 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HKFIIIAO_00274 1.49e-63 - - - - - - - -
HKFIIIAO_00275 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HKFIIIAO_00276 2.12e-216 - - - L ko:K07487 - ko00000 Transposase
HKFIIIAO_00277 4.76e-88 - - - L - - - manually curated
HKFIIIAO_00278 1.05e-162 - - - L ko:K07487 - ko00000 Transposase
HKFIIIAO_00279 3.96e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_00280 1.67e-135 - - - K - - - transcriptional regulator
HKFIIIAO_00281 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HKFIIIAO_00282 1.96e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HKFIIIAO_00283 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HKFIIIAO_00284 4.95e-281 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HKFIIIAO_00285 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_00286 1.87e-170 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00287 9.19e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00288 1.93e-73 - - - M - - - Lysin motif
HKFIIIAO_00289 1.43e-82 - - - M - - - LysM domain protein
HKFIIIAO_00290 8.27e-89 - - - L - - - manually curated
HKFIIIAO_00291 8.48e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HKFIIIAO_00292 1.01e-225 - - - - - - - -
HKFIIIAO_00293 1.91e-47 - - - - - - - -
HKFIIIAO_00294 8.27e-89 - - - L - - - manually curated
HKFIIIAO_00295 1.64e-87 - - - - - - - -
HKFIIIAO_00296 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HKFIIIAO_00297 1.96e-73 - - - - - - - -
HKFIIIAO_00298 6.19e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKFIIIAO_00299 2.65e-102 - - - S ko:K02348 - ko00000 GNAT family
HKFIIIAO_00300 1.24e-99 - - - K - - - Transcriptional regulator
HKFIIIAO_00301 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HKFIIIAO_00302 2.18e-53 - - - - - - - -
HKFIIIAO_00303 3.07e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_00304 1.31e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00305 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00306 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKFIIIAO_00307 3.68e-125 - - - K - - - Cupin domain
HKFIIIAO_00308 8.08e-110 - - - S - - - ASCH
HKFIIIAO_00309 1.88e-111 - - - K - - - GNAT family
HKFIIIAO_00310 1.02e-115 - - - K - - - acetyltransferase
HKFIIIAO_00311 2.06e-30 - - - - - - - -
HKFIIIAO_00312 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HKFIIIAO_00313 7.53e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_00314 1.08e-243 - - - - - - - -
HKFIIIAO_00315 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HKFIIIAO_00316 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HKFIIIAO_00318 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
HKFIIIAO_00319 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HKFIIIAO_00320 7.28e-42 - - - - - - - -
HKFIIIAO_00321 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKFIIIAO_00322 6.4e-54 - - - - - - - -
HKFIIIAO_00323 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HKFIIIAO_00324 5.83e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKFIIIAO_00325 4.03e-81 - - - S - - - CHY zinc finger
HKFIIIAO_00326 2.58e-283 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKFIIIAO_00327 1.1e-280 - - - - - - - -
HKFIIIAO_00328 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HKFIIIAO_00329 4.48e-256 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKFIIIAO_00330 6.53e-58 - - - - - - - -
HKFIIIAO_00331 1.24e-110 - - - K - - - Transcriptional regulator PadR-like family
HKFIIIAO_00332 0.0 - - - P - - - Major Facilitator Superfamily
HKFIIIAO_00333 3.35e-305 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HKFIIIAO_00334 3.01e-225 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKFIIIAO_00335 8.95e-60 - - - - - - - -
HKFIIIAO_00336 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
HKFIIIAO_00337 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKFIIIAO_00338 0.0 sufI - - Q - - - Multicopper oxidase
HKFIIIAO_00339 4.39e-71 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HKFIIIAO_00340 5.33e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HKFIIIAO_00341 1.96e-295 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HKFIIIAO_00342 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKFIIIAO_00343 2.16e-103 - - - - - - - -
HKFIIIAO_00344 3.45e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKFIIIAO_00345 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HKFIIIAO_00346 9.84e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_00347 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HKFIIIAO_00348 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKFIIIAO_00349 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_00350 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HKFIIIAO_00351 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKFIIIAO_00352 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HKFIIIAO_00353 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_00354 0.0 - - - M - - - domain protein
HKFIIIAO_00355 2.67e-89 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
HKFIIIAO_00356 1.82e-34 - - - S - - - Immunity protein 74
HKFIIIAO_00357 5.01e-226 - - - - - - - -
HKFIIIAO_00358 1.24e-11 - - - S - - - Immunity protein 22
HKFIIIAO_00359 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00360 7.22e-103 - - - S - - - ankyrin repeats
HKFIIIAO_00361 1.96e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKFIIIAO_00362 1.3e-49 - - - - - - - -
HKFIIIAO_00363 8.53e-28 - - - - - - - -
HKFIIIAO_00364 5.52e-64 - - - U - - - nuclease activity
HKFIIIAO_00365 2.05e-90 - - - - - - - -
HKFIIIAO_00366 1.32e-29 - - - - - - - -
HKFIIIAO_00368 1.44e-22 - - - - - - - -
HKFIIIAO_00369 4.17e-23 - - - - - - - -
HKFIIIAO_00370 6.85e-140 - - - L - - - Bacterial dnaA protein
HKFIIIAO_00371 1.02e-219 - - - L - - - Integrase core domain
HKFIIIAO_00372 1.48e-48 - - - - - - - -
HKFIIIAO_00374 4.56e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKFIIIAO_00375 1.84e-261 - - - EGP - - - Transporter, major facilitator family protein
HKFIIIAO_00376 3.41e-187 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_00377 3.91e-211 - - - K - - - Transcriptional regulator
HKFIIIAO_00378 8.38e-192 - - - S - - - hydrolase
HKFIIIAO_00379 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKFIIIAO_00380 1.78e-264 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKFIIIAO_00382 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00383 2.2e-149 - - - - - - - -
HKFIIIAO_00384 3.07e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_00385 1.93e-31 plnF - - - - - - -
HKFIIIAO_00386 2.59e-19 - - - - - - - -
HKFIIIAO_00387 1.65e-199 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKFIIIAO_00388 1.27e-277 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKFIIIAO_00389 1.17e-306 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HKFIIIAO_00390 1.83e-140 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00391 8.02e-152 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00392 1.86e-143 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00393 1.59e-145 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00394 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HKFIIIAO_00395 0.0 - - - L - - - DNA helicase
HKFIIIAO_00396 5.87e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HKFIIIAO_00397 2.35e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKFIIIAO_00398 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
HKFIIIAO_00399 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_00400 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_00401 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_00402 9.68e-34 - - - - - - - -
HKFIIIAO_00403 1.69e-97 - - - S - - - Domain of unknown function (DUF3284)
HKFIIIAO_00404 5.9e-46 - - - - - - - -
HKFIIIAO_00405 1.6e-77 chpA - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKFIIIAO_00406 1.2e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKFIIIAO_00407 7.87e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKFIIIAO_00408 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HKFIIIAO_00409 4.65e-229 - - - - - - - -
HKFIIIAO_00410 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HKFIIIAO_00411 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HKFIIIAO_00412 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
HKFIIIAO_00413 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKFIIIAO_00414 1.81e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HKFIIIAO_00415 2.52e-283 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_00416 5.1e-106 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HKFIIIAO_00418 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HKFIIIAO_00419 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKFIIIAO_00420 1.19e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKFIIIAO_00421 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HKFIIIAO_00422 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKFIIIAO_00423 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HKFIIIAO_00424 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKFIIIAO_00425 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HKFIIIAO_00426 2.95e-57 - - - S - - - ankyrin repeats
HKFIIIAO_00427 5.3e-49 - - - - - - - -
HKFIIIAO_00428 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HKFIIIAO_00429 5.78e-292 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKFIIIAO_00430 2.13e-191 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HKFIIIAO_00431 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKFIIIAO_00432 2.82e-236 - - - S - - - DUF218 domain
HKFIIIAO_00433 2.49e-178 - - - - - - - -
HKFIIIAO_00434 1.45e-191 yxeH - - S - - - hydrolase
HKFIIIAO_00435 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HKFIIIAO_00436 8.6e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HKFIIIAO_00437 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HKFIIIAO_00438 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKFIIIAO_00439 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKFIIIAO_00440 8.29e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKFIIIAO_00441 1.54e-288 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HKFIIIAO_00442 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HKFIIIAO_00443 2.31e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKFIIIAO_00444 6.59e-170 - - - S - - - YheO-like PAS domain
HKFIIIAO_00445 4.01e-36 - - - - - - - -
HKFIIIAO_00446 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKFIIIAO_00447 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKFIIIAO_00448 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HKFIIIAO_00449 1.49e-273 - - - J - - - translation release factor activity
HKFIIIAO_00450 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HKFIIIAO_00451 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
HKFIIIAO_00452 1.78e-191 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HKFIIIAO_00453 1.84e-189 - - - - - - - -
HKFIIIAO_00454 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKFIIIAO_00455 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKFIIIAO_00456 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKFIIIAO_00457 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKFIIIAO_00458 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HKFIIIAO_00459 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HKFIIIAO_00460 2.77e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00461 7.44e-203 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_00462 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_00463 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKFIIIAO_00464 1.51e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HKFIIIAO_00465 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKFIIIAO_00466 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKFIIIAO_00467 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HKFIIIAO_00468 1.82e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HKFIIIAO_00469 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKFIIIAO_00470 1.3e-110 queT - - S - - - QueT transporter
HKFIIIAO_00471 5.29e-211 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HKFIIIAO_00472 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_00473 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_00474 4.87e-148 - - - S - - - (CBS) domain
HKFIIIAO_00475 0.0 - - - S - - - Putative peptidoglycan binding domain
HKFIIIAO_00476 1.61e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKFIIIAO_00477 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKFIIIAO_00478 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKFIIIAO_00479 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HKFIIIAO_00480 7.72e-57 yabO - - J - - - S4 domain protein
HKFIIIAO_00482 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HKFIIIAO_00483 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HKFIIIAO_00484 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKFIIIAO_00485 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HKFIIIAO_00486 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKFIIIAO_00487 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKFIIIAO_00488 7.57e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKFIIIAO_00489 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HKFIIIAO_00492 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HKFIIIAO_00495 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HKFIIIAO_00496 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
HKFIIIAO_00500 5.21e-65 - - - S - - - Cupin 2, conserved barrel domain protein
HKFIIIAO_00501 1.38e-71 - - - S - - - Cupin domain
HKFIIIAO_00502 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HKFIIIAO_00503 1.86e-246 ysdE - - P - - - Citrate transporter
HKFIIIAO_00504 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HKFIIIAO_00505 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKFIIIAO_00506 2.4e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKFIIIAO_00507 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HKFIIIAO_00508 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKFIIIAO_00509 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKFIIIAO_00510 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKFIIIAO_00511 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKFIIIAO_00512 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HKFIIIAO_00513 1.71e-241 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00514 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HKFIIIAO_00515 5.34e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HKFIIIAO_00516 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HKFIIIAO_00517 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKFIIIAO_00519 2.02e-66 - - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_00525 3.32e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_00526 1.32e-19 - - - K - - - Helix-turn-helix
HKFIIIAO_00527 9.18e-129 - - - K - - - ORF6N domain
HKFIIIAO_00530 7.57e-12 - - - - - - - -
HKFIIIAO_00534 3.56e-28 - - - - - - - -
HKFIIIAO_00536 9.55e-185 - - - S - - - Protein of unknown function (DUF1351)
HKFIIIAO_00537 5.89e-153 - - - S - - - AAA domain
HKFIIIAO_00538 8.82e-111 - - - S - - - Protein of unknown function (DUF669)
HKFIIIAO_00539 3.56e-168 - - - S - - - Putative HNHc nuclease
HKFIIIAO_00540 1.52e-77 - - - L - - - DnaD domain protein
HKFIIIAO_00541 4.91e-170 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HKFIIIAO_00543 2.91e-62 - - - - - - - -
HKFIIIAO_00544 4.58e-06 - - - - - - - -
HKFIIIAO_00545 3.13e-106 - - - S - - - methyltransferase activity
HKFIIIAO_00547 1.57e-36 - - - S - - - YopX protein
HKFIIIAO_00550 3.33e-43 - - - - - - - -
HKFIIIAO_00556 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00557 4.24e-14 - - - - - - - -
HKFIIIAO_00558 1.92e-212 - - - S - - - Terminase
HKFIIIAO_00559 1.49e-48 - - - S - - - Phage portal protein
HKFIIIAO_00560 1.66e-55 - - - S - - - Phage portal protein
HKFIIIAO_00561 5.29e-74 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
HKFIIIAO_00562 5.26e-134 - - - S - - - Phage capsid family
HKFIIIAO_00563 6.56e-19 - - - - - - - -
HKFIIIAO_00564 4.31e-32 - - - - - - - -
HKFIIIAO_00565 1.12e-32 - - - - - - - -
HKFIIIAO_00566 4.57e-29 - - - - - - - -
HKFIIIAO_00567 1.07e-43 - - - S - - - Phage tail tube protein
HKFIIIAO_00569 1.68e-186 - - - L - - - Phage tail tape measure protein TP901
HKFIIIAO_00571 1.19e-139 - - - LM - - - DNA recombination
HKFIIIAO_00572 1.89e-23 - - - S - - - Protein of unknown function (DUF1617)
HKFIIIAO_00574 1.94e-60 - - - - - - - -
HKFIIIAO_00576 1.78e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
HKFIIIAO_00577 4.48e-94 - - - M - - - Glycosyl hydrolases family 25
HKFIIIAO_00578 2.27e-197 - - - G - - - Peptidase_C39 like family
HKFIIIAO_00579 2.63e-217 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKFIIIAO_00580 2.43e-174 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HKFIIIAO_00581 8.89e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HKFIIIAO_00582 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
HKFIIIAO_00583 0.0 levR - - K - - - Sigma-54 interaction domain
HKFIIIAO_00584 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKFIIIAO_00585 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKFIIIAO_00586 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKFIIIAO_00587 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HKFIIIAO_00588 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HKFIIIAO_00589 3.66e-184 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKFIIIAO_00590 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HKFIIIAO_00591 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKFIIIAO_00592 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HKFIIIAO_00593 8.57e-227 - - - EG - - - EamA-like transporter family
HKFIIIAO_00594 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKFIIIAO_00595 4.32e-150 zmp2 - - O - - - Zinc-dependent metalloprotease
HKFIIIAO_00596 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HKFIIIAO_00597 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKFIIIAO_00598 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HKFIIIAO_00599 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HKFIIIAO_00600 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKFIIIAO_00601 4.91e-265 yacL - - S - - - domain protein
HKFIIIAO_00602 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKFIIIAO_00603 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKFIIIAO_00604 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKFIIIAO_00605 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKFIIIAO_00606 3.4e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HKFIIIAO_00607 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HKFIIIAO_00608 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKFIIIAO_00609 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKFIIIAO_00610 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HKFIIIAO_00611 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_00612 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKFIIIAO_00613 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKFIIIAO_00614 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKFIIIAO_00615 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKFIIIAO_00616 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HKFIIIAO_00617 2.07e-87 - - - L - - - nuclease
HKFIIIAO_00618 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKFIIIAO_00619 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HKFIIIAO_00620 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKFIIIAO_00621 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKFIIIAO_00622 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HKFIIIAO_00623 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HKFIIIAO_00624 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKFIIIAO_00625 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKFIIIAO_00626 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKFIIIAO_00627 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKFIIIAO_00628 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HKFIIIAO_00629 1.05e-151 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKFIIIAO_00630 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HKFIIIAO_00631 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKFIIIAO_00632 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HKFIIIAO_00633 1.26e-211 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKFIIIAO_00634 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HKFIIIAO_00635 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HKFIIIAO_00636 2.09e-267 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKFIIIAO_00637 1.97e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HKFIIIAO_00638 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00639 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HKFIIIAO_00640 7.67e-176 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKFIIIAO_00641 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HKFIIIAO_00642 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HKFIIIAO_00643 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HKFIIIAO_00644 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKFIIIAO_00645 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKFIIIAO_00646 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HKFIIIAO_00647 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKFIIIAO_00648 1.13e-138 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00649 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKFIIIAO_00650 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKFIIIAO_00651 0.0 ydaO - - E - - - amino acid
HKFIIIAO_00652 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HKFIIIAO_00653 3.8e-198 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HKFIIIAO_00654 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HKFIIIAO_00655 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HKFIIIAO_00656 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HKFIIIAO_00657 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKFIIIAO_00658 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKFIIIAO_00659 3.41e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKFIIIAO_00660 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_00661 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_00662 1.05e-275 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HKFIIIAO_00663 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HKFIIIAO_00664 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKFIIIAO_00665 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HKFIIIAO_00666 4.48e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HKFIIIAO_00667 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HKFIIIAO_00668 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKFIIIAO_00669 2.69e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKFIIIAO_00670 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HKFIIIAO_00671 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HKFIIIAO_00672 6.77e-70 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HKFIIIAO_00673 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKFIIIAO_00674 3.62e-212 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKFIIIAO_00675 1.98e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HKFIIIAO_00676 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HKFIIIAO_00677 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
HKFIIIAO_00678 0.0 nox - - C - - - NADH oxidase
HKFIIIAO_00679 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKFIIIAO_00680 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HKFIIIAO_00681 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HKFIIIAO_00682 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKFIIIAO_00683 2.4e-169 - - - T - - - Putative diguanylate phosphodiesterase
HKFIIIAO_00684 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKFIIIAO_00685 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKFIIIAO_00686 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HKFIIIAO_00687 3.85e-151 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HKFIIIAO_00688 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKFIIIAO_00689 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKFIIIAO_00690 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKFIIIAO_00691 3.06e-301 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKFIIIAO_00692 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HKFIIIAO_00693 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
HKFIIIAO_00694 2e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HKFIIIAO_00695 1.46e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HKFIIIAO_00696 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HKFIIIAO_00697 9.85e-136 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00698 5.57e-115 - - - L - - - Transposase
HKFIIIAO_00699 4.87e-50 - - - L - - - Transposase
HKFIIIAO_00700 2.42e-247 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_00701 3.64e-224 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFIIIAO_00702 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKFIIIAO_00704 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HKFIIIAO_00705 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HKFIIIAO_00706 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKFIIIAO_00707 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HKFIIIAO_00708 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKFIIIAO_00709 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKFIIIAO_00710 2.42e-169 - - - - - - - -
HKFIIIAO_00711 0.0 eriC - - P ko:K03281 - ko00000 chloride
HKFIIIAO_00712 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKFIIIAO_00713 6.35e-178 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HKFIIIAO_00714 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKFIIIAO_00715 2.81e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKFIIIAO_00716 3.71e-211 - - - M - - - Domain of unknown function (DUF5011)
HKFIIIAO_00717 0.0 - - - M - - - Domain of unknown function (DUF5011)
HKFIIIAO_00718 0.0 - - - M - - - Domain of unknown function (DUF5011)
HKFIIIAO_00719 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_00720 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_00721 7.98e-137 - - - - - - - -
HKFIIIAO_00722 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_00723 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKFIIIAO_00724 5e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HKFIIIAO_00725 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HKFIIIAO_00726 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HKFIIIAO_00727 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKFIIIAO_00728 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HKFIIIAO_00729 1.03e-211 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HKFIIIAO_00730 2.54e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HKFIIIAO_00731 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HKFIIIAO_00732 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_00733 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
HKFIIIAO_00734 3.39e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKFIIIAO_00735 2.18e-182 ybbR - - S - - - YbbR-like protein
HKFIIIAO_00736 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKFIIIAO_00737 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKFIIIAO_00738 4.47e-158 - - - T - - - EAL domain
HKFIIIAO_00739 3.27e-189 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_00740 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00741 4.87e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HKFIIIAO_00742 3.38e-70 - - - - - - - -
HKFIIIAO_00743 2.49e-95 - - - - - - - -
HKFIIIAO_00744 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HKFIIIAO_00745 3.51e-197 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HKFIIIAO_00746 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKFIIIAO_00747 6.37e-186 - - - - - - - -
HKFIIIAO_00749 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HKFIIIAO_00750 3.88e-46 - - - - - - - -
HKFIIIAO_00751 2.08e-117 - - - V - - - VanZ like family
HKFIIIAO_00752 2.14e-314 - - - EGP - - - Major Facilitator
HKFIIIAO_00753 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKFIIIAO_00754 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKFIIIAO_00755 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKFIIIAO_00756 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HKFIIIAO_00757 6.16e-107 - - - K - - - Transcriptional regulator
HKFIIIAO_00758 1.36e-27 - - - - - - - -
HKFIIIAO_00759 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HKFIIIAO_00760 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_00761 1.06e-195 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HKFIIIAO_00762 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_00763 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HKFIIIAO_00764 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKFIIIAO_00765 0.0 oatA - - I - - - Acyltransferase
HKFIIIAO_00766 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKFIIIAO_00767 1.89e-90 - - - O - - - OsmC-like protein
HKFIIIAO_00768 1.09e-60 - - - - - - - -
HKFIIIAO_00769 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HKFIIIAO_00770 6.12e-115 - - - - - - - -
HKFIIIAO_00771 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HKFIIIAO_00772 7.48e-96 - - - F - - - Nudix hydrolase
HKFIIIAO_00773 1.48e-27 - - - - - - - -
HKFIIIAO_00774 2.45e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HKFIIIAO_00775 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HKFIIIAO_00776 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HKFIIIAO_00777 1.01e-188 - - - - - - - -
HKFIIIAO_00778 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HKFIIIAO_00779 7.9e-269 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKFIIIAO_00780 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFIIIAO_00781 5.2e-54 - - - - - - - -
HKFIIIAO_00783 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_00784 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HKFIIIAO_00785 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00786 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_00787 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKFIIIAO_00788 1.05e-33 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HKFIIIAO_00789 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00790 4.38e-144 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HKFIIIAO_00791 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HKFIIIAO_00792 3.16e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HKFIIIAO_00793 0.0 steT - - E ko:K03294 - ko00000 amino acid
HKFIIIAO_00794 1.26e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_00795 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
HKFIIIAO_00796 8.83e-93 - - - K - - - MarR family
HKFIIIAO_00797 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_00798 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HKFIIIAO_00799 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00800 1.7e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKFIIIAO_00801 4.6e-102 rppH3 - - F - - - NUDIX domain
HKFIIIAO_00802 1.95e-61 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HKFIIIAO_00803 1.61e-36 - - - - - - - -
HKFIIIAO_00804 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
HKFIIIAO_00805 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
HKFIIIAO_00806 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HKFIIIAO_00807 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HKFIIIAO_00808 1.11e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HKFIIIAO_00809 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HKFIIIAO_00810 2.08e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HKFIIIAO_00811 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HKFIIIAO_00812 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HKFIIIAO_00814 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HKFIIIAO_00815 3.61e-76 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HKFIIIAO_00816 0.0 - - - L - - - DEAD-like helicases superfamily
HKFIIIAO_00817 3.66e-162 yeeC - - P - - - T5orf172
HKFIIIAO_00820 1.96e-81 - - - L - - - AAA domain
HKFIIIAO_00821 6.18e-130 - - - K - - - Transcriptional regulator, AbiEi antitoxin
HKFIIIAO_00822 9.75e-176 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKFIIIAO_00823 3.01e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_00824 1.04e-69 - - - - - - - -
HKFIIIAO_00825 8.89e-80 - - - K - - - Helix-turn-helix domain
HKFIIIAO_00826 1.57e-140 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_00827 1.22e-242 - - - S - - - Cysteine-rich secretory protein family
HKFIIIAO_00828 1.59e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKFIIIAO_00829 1.96e-117 - - - D - - - nuclear chromosome segregation
HKFIIIAO_00830 6.46e-111 - - - - - - - -
HKFIIIAO_00831 2.25e-204 - - - S - - - Domain of unknown function (DUF4767)
HKFIIIAO_00832 6.35e-69 - - - - - - - -
HKFIIIAO_00833 8.49e-60 - - - S - - - MORN repeat
HKFIIIAO_00834 0.0 XK27_09800 - - I - - - Acyltransferase family
HKFIIIAO_00835 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HKFIIIAO_00836 1.95e-116 - - - - - - - -
HKFIIIAO_00837 5.74e-32 - - - - - - - -
HKFIIIAO_00838 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HKFIIIAO_00839 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HKFIIIAO_00840 3.96e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_00841 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HKFIIIAO_00842 2.57e-212 yjdB - - S - - - Domain of unknown function (DUF4767)
HKFIIIAO_00843 1.05e-61 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKFIIIAO_00844 1.14e-181 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKFIIIAO_00845 3.07e-84 - - - S - - - Putative inner membrane protein (DUF1819)
HKFIIIAO_00846 1.15e-93 - - - S - - - Domain of unknown function (DUF1788)
HKFIIIAO_00847 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HKFIIIAO_00848 0.0 - - - LV - - - Eco57I restriction-modification methylase
HKFIIIAO_00849 2.15e-189 - - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_00850 3.73e-221 - - - LV - - - Eco57I restriction-modification methylase
HKFIIIAO_00851 2.34e-280 - - - S - - - PglZ domain
HKFIIIAO_00852 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HKFIIIAO_00853 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HKFIIIAO_00854 5.97e-61 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HKFIIIAO_00855 1.44e-33 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HKFIIIAO_00856 1.23e-108 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_00858 1.39e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HKFIIIAO_00859 0.0 - - - M - - - MucBP domain
HKFIIIAO_00860 1.42e-08 - - - - - - - -
HKFIIIAO_00861 5.16e-115 - - - S - - - AAA domain
HKFIIIAO_00862 1.97e-175 - - - K - - - sequence-specific DNA binding
HKFIIIAO_00863 1.05e-121 - - - K - - - Helix-turn-helix domain
HKFIIIAO_00864 6.52e-219 - - - K - - - Transcriptional regulator
HKFIIIAO_00865 0.0 - - - C - - - FMN_bind
HKFIIIAO_00867 4.13e-104 - - - K - - - Transcriptional regulator
HKFIIIAO_00868 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKFIIIAO_00869 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HKFIIIAO_00870 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HKFIIIAO_00871 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKFIIIAO_00872 5.38e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKFIIIAO_00873 9.05e-55 - - - - - - - -
HKFIIIAO_00874 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
HKFIIIAO_00875 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKFIIIAO_00876 9.95e-211 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKFIIIAO_00877 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_00878 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
HKFIIIAO_00879 1.86e-242 - - - - - - - -
HKFIIIAO_00880 1.89e-277 yibE - - S - - - overlaps another CDS with the same product name
HKFIIIAO_00881 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
HKFIIIAO_00882 4.97e-132 - - - K - - - FR47-like protein
HKFIIIAO_00883 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
HKFIIIAO_00884 2.74e-63 - - - - - - - -
HKFIIIAO_00885 2.98e-246 - - - I - - - alpha/beta hydrolase fold
HKFIIIAO_00886 0.0 xylP2 - - G - - - symporter
HKFIIIAO_00887 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKFIIIAO_00888 2.42e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HKFIIIAO_00889 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HKFIIIAO_00890 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HKFIIIAO_00891 1.43e-155 azlC - - E - - - branched-chain amino acid
HKFIIIAO_00892 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HKFIIIAO_00893 1.46e-170 - - - - - - - -
HKFIIIAO_00894 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
HKFIIIAO_00895 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HKFIIIAO_00896 7.79e-112 - - - K - - - MerR HTH family regulatory protein
HKFIIIAO_00897 1.36e-77 - - - - - - - -
HKFIIIAO_00898 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HKFIIIAO_00899 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKFIIIAO_00900 4.6e-169 - - - S - - - Putative threonine/serine exporter
HKFIIIAO_00901 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HKFIIIAO_00902 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKFIIIAO_00903 4.15e-153 - - - I - - - phosphatase
HKFIIIAO_00904 3.88e-198 - - - I - - - alpha/beta hydrolase fold
HKFIIIAO_00905 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKFIIIAO_00906 9.82e-118 - - - K - - - Transcriptional regulator
HKFIIIAO_00907 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_00908 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HKFIIIAO_00909 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HKFIIIAO_00910 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HKFIIIAO_00911 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKFIIIAO_00919 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HKFIIIAO_00920 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKFIIIAO_00921 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_00922 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFIIIAO_00923 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFIIIAO_00924 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKFIIIAO_00925 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKFIIIAO_00926 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKFIIIAO_00927 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HKFIIIAO_00928 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKFIIIAO_00929 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HKFIIIAO_00930 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKFIIIAO_00931 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKFIIIAO_00932 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKFIIIAO_00933 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKFIIIAO_00934 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKFIIIAO_00935 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKFIIIAO_00936 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HKFIIIAO_00937 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKFIIIAO_00938 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKFIIIAO_00939 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKFIIIAO_00940 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKFIIIAO_00941 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKFIIIAO_00942 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKFIIIAO_00943 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKFIIIAO_00944 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKFIIIAO_00945 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HKFIIIAO_00946 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKFIIIAO_00947 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKFIIIAO_00948 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKFIIIAO_00949 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKFIIIAO_00950 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKFIIIAO_00951 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKFIIIAO_00952 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKFIIIAO_00953 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HKFIIIAO_00954 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKFIIIAO_00955 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HKFIIIAO_00956 5.37e-112 - - - S - - - NusG domain II
HKFIIIAO_00957 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HKFIIIAO_00958 3.19e-194 - - - S - - - FMN_bind
HKFIIIAO_00959 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKFIIIAO_00960 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFIIIAO_00961 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFIIIAO_00962 2.39e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKFIIIAO_00963 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKFIIIAO_00964 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKFIIIAO_00965 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HKFIIIAO_00966 4.05e-208 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HKFIIIAO_00967 2.46e-235 - - - S - - - Membrane
HKFIIIAO_00968 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HKFIIIAO_00969 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKFIIIAO_00970 2.25e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKFIIIAO_00971 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HKFIIIAO_00972 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKFIIIAO_00974 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HKFIIIAO_00975 4.33e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HKFIIIAO_00976 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HKFIIIAO_00977 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HKFIIIAO_00978 1.28e-253 - - - K - - - Helix-turn-helix domain
HKFIIIAO_00979 1.57e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKFIIIAO_00980 8.31e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKFIIIAO_00981 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HKFIIIAO_00982 1.73e-221 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKFIIIAO_00983 1.18e-66 - - - - - - - -
HKFIIIAO_00984 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKFIIIAO_00985 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HKFIIIAO_00986 8.69e-230 citR - - K - - - sugar-binding domain protein
HKFIIIAO_00987 3.88e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HKFIIIAO_00988 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKFIIIAO_00989 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HKFIIIAO_00990 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HKFIIIAO_00991 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HKFIIIAO_00992 2.06e-234 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKFIIIAO_00994 9.54e-65 - - - K - - - sequence-specific DNA binding
HKFIIIAO_00999 1.38e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKFIIIAO_01000 2.05e-231 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKFIIIAO_01001 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKFIIIAO_01002 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HKFIIIAO_01003 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKFIIIAO_01004 3.06e-205 mleR2 - - K - - - LysR family transcriptional regulator
HKFIIIAO_01005 6.5e-215 mleR - - K - - - LysR family
HKFIIIAO_01006 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HKFIIIAO_01007 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HKFIIIAO_01008 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HKFIIIAO_01009 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HKFIIIAO_01010 6.07e-33 - - - - - - - -
HKFIIIAO_01011 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HKFIIIAO_01012 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HKFIIIAO_01013 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HKFIIIAO_01014 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKFIIIAO_01015 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKFIIIAO_01016 1.02e-121 - - - S - - - L,D-transpeptidase catalytic domain
HKFIIIAO_01017 1.24e-66 - - - S - - - protein conserved in bacteria
HKFIIIAO_01018 4.87e-234 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKFIIIAO_01019 4.92e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HKFIIIAO_01020 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HKFIIIAO_01021 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HKFIIIAO_01022 8.19e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKFIIIAO_01023 1.13e-120 yebE - - S - - - UPF0316 protein
HKFIIIAO_01024 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKFIIIAO_01025 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HKFIIIAO_01026 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKFIIIAO_01027 3.86e-262 camS - - S - - - sex pheromone
HKFIIIAO_01028 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKFIIIAO_01029 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKFIIIAO_01030 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKFIIIAO_01031 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HKFIIIAO_01032 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKFIIIAO_01033 3.22e-129 yobS - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_01034 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HKFIIIAO_01035 2.75e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_01036 1.94e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_01037 9.33e-195 gntR - - K - - - rpiR family
HKFIIIAO_01038 1.67e-177 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HKFIIIAO_01039 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
HKFIIIAO_01040 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HKFIIIAO_01041 1.94e-245 mocA - - S - - - Oxidoreductase
HKFIIIAO_01042 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
HKFIIIAO_01044 7.42e-99 int3 - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_01045 9.37e-68 - - - - - - - -
HKFIIIAO_01049 1.18e-88 - - - S - - - DNA binding
HKFIIIAO_01052 1.38e-07 - - - - - - - -
HKFIIIAO_01055 4.89e-26 - - - - - - - -
HKFIIIAO_01057 7.02e-187 - - - S - - - Protein of unknown function (DUF1351)
HKFIIIAO_01058 1.89e-149 - - - S - - - AAA domain
HKFIIIAO_01059 1.53e-111 - - - S - - - Protein of unknown function (DUF669)
HKFIIIAO_01060 1.13e-151 - - - S - - - Putative HNHc nuclease
HKFIIIAO_01061 1.34e-54 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HKFIIIAO_01062 1.41e-169 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HKFIIIAO_01064 1.16e-108 - - - - - - - -
HKFIIIAO_01065 5.49e-85 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKFIIIAO_01067 1.34e-28 - - - S - - - YopX protein
HKFIIIAO_01070 9.87e-90 - - - - - - - -
HKFIIIAO_01071 1.08e-28 - - - - - - - -
HKFIIIAO_01072 1.2e-46 - - - S - - - helicase activity
HKFIIIAO_01073 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_01074 3.13e-31 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HKFIIIAO_01075 6.2e-95 - - - L - - - DNA methylase
HKFIIIAO_01076 6.69e-116 - - - L - - - HNH nucleases
HKFIIIAO_01077 1.3e-100 - - - L - - - Phage terminase, small subunit
HKFIIIAO_01078 0.0 - - - S - - - Phage Terminase
HKFIIIAO_01079 3.74e-32 - - - S - - - Protein of unknown function (DUF1056)
HKFIIIAO_01080 1.79e-286 - - - S - - - Phage portal protein
HKFIIIAO_01081 2.09e-164 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HKFIIIAO_01082 1.51e-264 - - - S - - - Phage capsid family
HKFIIIAO_01083 5.64e-66 - - - S - - - Phage gp6-like head-tail connector protein
HKFIIIAO_01084 3.45e-76 - - - S - - - Phage head-tail joining protein
HKFIIIAO_01085 1.12e-86 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HKFIIIAO_01086 9.09e-75 - - - S - - - Protein of unknown function (DUF806)
HKFIIIAO_01087 5.32e-134 - - - S - - - Phage tail tube protein
HKFIIIAO_01088 2.25e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
HKFIIIAO_01089 2.6e-33 - - - - - - - -
HKFIIIAO_01090 0.0 - - - D - - - domain protein
HKFIIIAO_01091 0.0 - - - S - - - Phage tail protein
HKFIIIAO_01092 0.0 - - - S - - - Phage minor structural protein
HKFIIIAO_01093 1.75e-58 - - - - - - - -
HKFIIIAO_01096 5.62e-68 - - - - - - - -
HKFIIIAO_01097 1.35e-259 - - - M - - - Glycosyl hydrolases family 25
HKFIIIAO_01098 2.08e-46 - - - S - - - Haemolysin XhlA
HKFIIIAO_01099 1.76e-56 - - - S - - - Bacteriophage holin
HKFIIIAO_01100 3.93e-99 - - - T - - - Universal stress protein family
HKFIIIAO_01101 1.82e-312 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_01102 7.88e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_01104 7.62e-97 - - - - - - - -
HKFIIIAO_01105 2.9e-139 - - - - - - - -
HKFIIIAO_01106 7e-208 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_01107 2.22e-169 - - - L - - - Helix-turn-helix domain
HKFIIIAO_01108 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HKFIIIAO_01109 4.4e-273 pbpX - - V - - - Beta-lactamase
HKFIIIAO_01110 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKFIIIAO_01111 1.23e-200 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HKFIIIAO_01112 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_01113 3.69e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HKFIIIAO_01115 8.43e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_01116 6.17e-71 - - - S - - - SMI1-KNR4 cell-wall
HKFIIIAO_01118 4.93e-170 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HKFIIIAO_01119 7.72e-228 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HKFIIIAO_01120 6.91e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HKFIIIAO_01121 5.58e-260 cps3D - - - - - - -
HKFIIIAO_01122 5.23e-206 cps3F - - - - - - -
HKFIIIAO_01123 1.75e-256 cps3H - - - - - - -
HKFIIIAO_01124 5.67e-257 cps3I - - G - - - Acyltransferase family
HKFIIIAO_01125 2.94e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
HKFIIIAO_01126 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_01127 1.71e-304 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HKFIIIAO_01128 4.83e-151 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HKFIIIAO_01129 2.59e-69 - - - - - - - -
HKFIIIAO_01130 2.54e-46 - - - S - - - Protein of unknown function (DUF2922)
HKFIIIAO_01131 1.17e-42 - - - - - - - -
HKFIIIAO_01132 5.7e-36 - - - - - - - -
HKFIIIAO_01133 3.82e-128 - - - K - - - DNA-templated transcription, initiation
HKFIIIAO_01134 1.39e-169 - - - - - - - -
HKFIIIAO_01135 3.93e-180 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HKFIIIAO_01136 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HKFIIIAO_01137 5.34e-168 lytE - - M - - - NlpC/P60 family
HKFIIIAO_01138 8.01e-64 - - - K - - - sequence-specific DNA binding
HKFIIIAO_01139 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HKFIIIAO_01140 4.22e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKFIIIAO_01141 1.13e-257 yueF - - S - - - AI-2E family transporter
HKFIIIAO_01142 3.5e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HKFIIIAO_01143 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HKFIIIAO_01144 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HKFIIIAO_01145 4.77e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HKFIIIAO_01146 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HKFIIIAO_01147 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKFIIIAO_01148 0.0 - - - - - - - -
HKFIIIAO_01149 2.12e-252 - - - M - - - MucBP domain
HKFIIIAO_01150 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
HKFIIIAO_01151 4.78e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
HKFIIIAO_01152 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HKFIIIAO_01153 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_01154 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKFIIIAO_01155 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKFIIIAO_01156 2.81e-257 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKFIIIAO_01157 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKFIIIAO_01158 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HKFIIIAO_01159 2.5e-132 - - - L - - - Integrase
HKFIIIAO_01160 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HKFIIIAO_01161 5.6e-41 - - - - - - - -
HKFIIIAO_01162 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HKFIIIAO_01163 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKFIIIAO_01164 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKFIIIAO_01165 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKFIIIAO_01166 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKFIIIAO_01167 3.79e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HKFIIIAO_01168 5.8e-291 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKFIIIAO_01169 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HKFIIIAO_01170 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKFIIIAO_01173 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HKFIIIAO_01185 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HKFIIIAO_01186 1.5e-235 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HKFIIIAO_01187 2.07e-123 - - - - - - - -
HKFIIIAO_01188 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HKFIIIAO_01189 1.78e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HKFIIIAO_01190 2.04e-143 - - - K - - - helix_turn_helix, arabinose operon control protein
HKFIIIAO_01191 1.98e-184 lipA - - I - - - Carboxylesterase family
HKFIIIAO_01192 4.41e-22 - - - P - - - Major Facilitator Superfamily
HKFIIIAO_01193 9.04e-155 - - - P - - - Major Facilitator Superfamily
HKFIIIAO_01194 5.42e-142 - - - GK - - - ROK family
HKFIIIAO_01195 3.26e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKFIIIAO_01196 2.42e-238 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HKFIIIAO_01197 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HKFIIIAO_01198 1.07e-213 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HKFIIIAO_01199 4.94e-197 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_01200 1.94e-149 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_01201 6.75e-157 - - - - - - - -
HKFIIIAO_01202 1.13e-272 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKFIIIAO_01203 0.0 mdr - - EGP - - - Major Facilitator
HKFIIIAO_01204 4.54e-310 - - - N - - - Cell shape-determining protein MreB
HKFIIIAO_01205 0.0 - - - S - - - Pfam Methyltransferase
HKFIIIAO_01206 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_01207 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_01208 9.32e-40 - - - - - - - -
HKFIIIAO_01209 8.7e-122 mraW1 - - J - - - Putative rRNA methylase
HKFIIIAO_01210 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HKFIIIAO_01211 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HKFIIIAO_01212 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HKFIIIAO_01213 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKFIIIAO_01214 3.03e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKFIIIAO_01215 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HKFIIIAO_01216 9.54e-109 - - - T - - - Belongs to the universal stress protein A family
HKFIIIAO_01217 1.45e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HKFIIIAO_01218 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_01219 6.16e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_01220 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKFIIIAO_01221 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HKFIIIAO_01222 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HKFIIIAO_01223 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKFIIIAO_01224 1.48e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HKFIIIAO_01226 3.03e-135 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HKFIIIAO_01227 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_01228 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HKFIIIAO_01230 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKFIIIAO_01231 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_01232 1.64e-151 - - - GM - - - NAD(P)H-binding
HKFIIIAO_01233 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKFIIIAO_01234 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_01235 7.83e-140 - - - - - - - -
HKFIIIAO_01236 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKFIIIAO_01237 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HKFIIIAO_01238 5.16e-72 - - - - - - - -
HKFIIIAO_01239 4.56e-78 - - - - - - - -
HKFIIIAO_01240 3.54e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_01241 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_01242 8.82e-119 - - - - - - - -
HKFIIIAO_01243 7.12e-62 - - - - - - - -
HKFIIIAO_01244 0.0 uvrA2 - - L - - - ABC transporter
HKFIIIAO_01247 4.29e-87 - - - - - - - -
HKFIIIAO_01248 9.03e-16 - - - - - - - -
HKFIIIAO_01249 1.12e-236 - - - - - - - -
HKFIIIAO_01250 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HKFIIIAO_01251 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HKFIIIAO_01252 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKFIIIAO_01253 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKFIIIAO_01254 0.0 - - - S - - - Protein conserved in bacteria
HKFIIIAO_01255 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKFIIIAO_01256 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HKFIIIAO_01257 2.54e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HKFIIIAO_01258 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HKFIIIAO_01259 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HKFIIIAO_01260 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_01261 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_01262 2.69e-316 dinF - - V - - - MatE
HKFIIIAO_01263 1.79e-42 - - - - - - - -
HKFIIIAO_01266 8.2e-102 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HKFIIIAO_01267 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HKFIIIAO_01268 4.64e-106 - - - - - - - -
HKFIIIAO_01269 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HKFIIIAO_01270 6.25e-138 - - - - - - - -
HKFIIIAO_01271 0.0 celR - - K - - - PRD domain
HKFIIIAO_01272 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
HKFIIIAO_01273 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKFIIIAO_01274 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKFIIIAO_01275 1.02e-285 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_01276 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKFIIIAO_01277 7.06e-271 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HKFIIIAO_01278 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HKFIIIAO_01279 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKFIIIAO_01280 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HKFIIIAO_01281 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HKFIIIAO_01282 5.58e-271 arcT - - E - - - Aminotransferase
HKFIIIAO_01283 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKFIIIAO_01284 2.43e-18 - - - - - - - -
HKFIIIAO_01285 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HKFIIIAO_01286 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
HKFIIIAO_01287 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HKFIIIAO_01288 0.0 yhaN - - L - - - AAA domain
HKFIIIAO_01289 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFIIIAO_01290 1.05e-272 - - - - - - - -
HKFIIIAO_01291 2.41e-233 - - - M - - - Peptidase family S41
HKFIIIAO_01292 6.59e-227 - - - K - - - LysR substrate binding domain
HKFIIIAO_01293 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HKFIIIAO_01294 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HKFIIIAO_01295 4.43e-129 - - - - - - - -
HKFIIIAO_01296 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HKFIIIAO_01297 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
HKFIIIAO_01298 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKFIIIAO_01299 4.29e-26 - - - S - - - NUDIX domain
HKFIIIAO_01300 0.0 - - - S - - - membrane
HKFIIIAO_01301 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_01302 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_01303 1.7e-112 - - - S - - - membrane
HKFIIIAO_01304 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKFIIIAO_01305 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HKFIIIAO_01306 4.9e-283 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKFIIIAO_01307 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKFIIIAO_01308 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HKFIIIAO_01309 1.96e-137 - - - - - - - -
HKFIIIAO_01310 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HKFIIIAO_01311 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_01312 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HKFIIIAO_01313 0.0 - - - - - - - -
HKFIIIAO_01314 1.65e-80 - - - - - - - -
HKFIIIAO_01315 9.64e-248 - - - S - - - Fn3-like domain
HKFIIIAO_01316 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_01317 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_01318 1.78e-153 draG - - O - - - ADP-ribosylglycohydrolase
HKFIIIAO_01319 1.55e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKFIIIAO_01320 4.06e-65 - - - - - - - -
HKFIIIAO_01321 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HKFIIIAO_01322 6.35e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01323 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_01324 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
HKFIIIAO_01325 2.8e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKFIIIAO_01326 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HKFIIIAO_01327 1.29e-148 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKFIIIAO_01328 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HKFIIIAO_01329 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HKFIIIAO_01330 3.04e-29 - - - S - - - Virus attachment protein p12 family
HKFIIIAO_01331 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HKFIIIAO_01332 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HKFIIIAO_01333 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HKFIIIAO_01334 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HKFIIIAO_01335 3.17e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKFIIIAO_01336 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HKFIIIAO_01337 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HKFIIIAO_01338 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
HKFIIIAO_01339 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HKFIIIAO_01340 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HKFIIIAO_01341 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKFIIIAO_01342 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKFIIIAO_01343 1.92e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKFIIIAO_01344 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKFIIIAO_01345 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HKFIIIAO_01346 3.5e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HKFIIIAO_01347 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKFIIIAO_01348 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKFIIIAO_01349 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HKFIIIAO_01350 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKFIIIAO_01351 1.87e-72 - - - - - - - -
HKFIIIAO_01352 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HKFIIIAO_01353 1.18e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKFIIIAO_01354 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
HKFIIIAO_01355 2.79e-174 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HKFIIIAO_01356 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HKFIIIAO_01357 8.99e-114 - - - - - - - -
HKFIIIAO_01358 1.34e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HKFIIIAO_01359 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HKFIIIAO_01360 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HKFIIIAO_01361 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKFIIIAO_01362 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HKFIIIAO_01363 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKFIIIAO_01364 3.3e-180 yqeM - - Q - - - Methyltransferase
HKFIIIAO_01365 3.04e-280 ylbM - - S - - - Belongs to the UPF0348 family
HKFIIIAO_01366 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HKFIIIAO_01367 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
HKFIIIAO_01368 1.09e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKFIIIAO_01369 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKFIIIAO_01370 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HKFIIIAO_01371 1.38e-155 csrR - - K - - - response regulator
HKFIIIAO_01372 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKFIIIAO_01373 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HKFIIIAO_01374 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HKFIIIAO_01375 9.59e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKFIIIAO_01376 1.77e-122 - - - S - - - SdpI/YhfL protein family
HKFIIIAO_01377 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKFIIIAO_01378 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HKFIIIAO_01379 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKFIIIAO_01380 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFIIIAO_01381 4.45e-83 yodB - - K - - - Transcriptional regulator, HxlR family
HKFIIIAO_01382 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKFIIIAO_01383 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKFIIIAO_01384 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKFIIIAO_01385 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HKFIIIAO_01386 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKFIIIAO_01387 3.78e-143 - - - S - - - membrane
HKFIIIAO_01388 2.33e-98 - - - K - - - LytTr DNA-binding domain
HKFIIIAO_01389 2.5e-71 yneR - - S - - - Belongs to the HesB IscA family
HKFIIIAO_01390 0.0 - - - S - - - membrane
HKFIIIAO_01391 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKFIIIAO_01392 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKFIIIAO_01393 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKFIIIAO_01394 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HKFIIIAO_01395 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HKFIIIAO_01396 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HKFIIIAO_01397 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HKFIIIAO_01398 4.7e-89 yqhL - - P - - - Rhodanese-like protein
HKFIIIAO_01399 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HKFIIIAO_01400 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HKFIIIAO_01401 3.8e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKFIIIAO_01402 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HKFIIIAO_01403 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HKFIIIAO_01404 1.77e-205 - - - - - - - -
HKFIIIAO_01405 1.34e-232 - - - - - - - -
HKFIIIAO_01406 8.37e-126 - - - S - - - Protein conserved in bacteria
HKFIIIAO_01407 3.11e-73 - - - - - - - -
HKFIIIAO_01408 2.97e-41 - - - - - - - -
HKFIIIAO_01411 9.81e-27 - - - - - - - -
HKFIIIAO_01412 8.15e-125 - - - K - - - Transcriptional regulator
HKFIIIAO_01413 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HKFIIIAO_01414 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HKFIIIAO_01415 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HKFIIIAO_01416 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKFIIIAO_01417 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKFIIIAO_01418 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HKFIIIAO_01419 2.82e-91 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKFIIIAO_01420 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKFIIIAO_01421 1.14e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKFIIIAO_01422 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKFIIIAO_01423 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKFIIIAO_01424 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HKFIIIAO_01425 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKFIIIAO_01426 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HKFIIIAO_01427 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01428 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_01429 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKFIIIAO_01430 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_01431 8.28e-73 - - - - - - - -
HKFIIIAO_01432 2.83e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HKFIIIAO_01433 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKFIIIAO_01434 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKFIIIAO_01435 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKFIIIAO_01436 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKFIIIAO_01437 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKFIIIAO_01438 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HKFIIIAO_01439 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HKFIIIAO_01440 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKFIIIAO_01441 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HKFIIIAO_01442 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HKFIIIAO_01443 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HKFIIIAO_01444 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HKFIIIAO_01445 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HKFIIIAO_01446 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKFIIIAO_01447 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKFIIIAO_01448 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKFIIIAO_01449 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKFIIIAO_01450 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HKFIIIAO_01451 2.85e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKFIIIAO_01452 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKFIIIAO_01453 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKFIIIAO_01454 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HKFIIIAO_01455 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HKFIIIAO_01456 6.42e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKFIIIAO_01457 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HKFIIIAO_01458 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKFIIIAO_01459 3.2e-70 - - - - - - - -
HKFIIIAO_01460 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HKFIIIAO_01461 9.06e-112 - - - - - - - -
HKFIIIAO_01462 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKFIIIAO_01463 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HKFIIIAO_01465 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HKFIIIAO_01466 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HKFIIIAO_01467 6.03e-226 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKFIIIAO_01468 1.2e-165 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HKFIIIAO_01469 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HKFIIIAO_01470 6.25e-288 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKFIIIAO_01471 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKFIIIAO_01472 5.89e-126 entB - - Q - - - Isochorismatase family
HKFIIIAO_01473 2.04e-226 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HKFIIIAO_01474 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
HKFIIIAO_01475 1.62e-276 - - - E - - - glutamate:sodium symporter activity
HKFIIIAO_01476 6.54e-272 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HKFIIIAO_01477 2.69e-252 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HKFIIIAO_01478 1.49e-77 - - - S - - - Protein of unknown function (DUF1648)
HKFIIIAO_01480 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_01481 1.62e-229 yneE - - K - - - Transcriptional regulator
HKFIIIAO_01482 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKFIIIAO_01483 1.62e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKFIIIAO_01484 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKFIIIAO_01485 3.47e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HKFIIIAO_01486 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HKFIIIAO_01487 7.64e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKFIIIAO_01488 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKFIIIAO_01489 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HKFIIIAO_01490 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HKFIIIAO_01491 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKFIIIAO_01492 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HKFIIIAO_01493 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HKFIIIAO_01494 5.01e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HKFIIIAO_01495 1.48e-161 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HKFIIIAO_01496 7.52e-207 - - - K - - - LysR substrate binding domain
HKFIIIAO_01497 2.01e-113 ykhA - - I - - - Thioesterase superfamily
HKFIIIAO_01498 4.4e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKFIIIAO_01499 6.05e-121 - - - K - - - transcriptional regulator
HKFIIIAO_01500 0.0 - - - EGP - - - Major Facilitator
HKFIIIAO_01501 1.14e-193 - - - O - - - Band 7 protein
HKFIIIAO_01502 1.48e-71 - - - - - - - -
HKFIIIAO_01503 2.02e-39 - - - - - - - -
HKFIIIAO_01504 1.33e-273 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HKFIIIAO_01505 1.05e-41 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_01506 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HKFIIIAO_01507 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HKFIIIAO_01508 2.05e-55 - - - - - - - -
HKFIIIAO_01509 2.22e-169 - - - L - - - Helix-turn-helix domain
HKFIIIAO_01510 4.05e-207 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_01511 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HKFIIIAO_01512 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
HKFIIIAO_01513 5.58e-87 - - - S - - - Protein of unknown function (DUF805)
HKFIIIAO_01514 3.6e-211 - - - I - - - Diacylglycerol kinase catalytic domain
HKFIIIAO_01515 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_01516 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_01517 1.51e-48 - - - - - - - -
HKFIIIAO_01518 5.79e-21 - - - - - - - -
HKFIIIAO_01519 2.22e-55 - - - S - - - transglycosylase associated protein
HKFIIIAO_01520 4e-40 - - - S - - - CsbD-like
HKFIIIAO_01521 1.06e-53 - - - - - - - -
HKFIIIAO_01522 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKFIIIAO_01523 2.41e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HKFIIIAO_01524 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKFIIIAO_01525 1.48e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HKFIIIAO_01526 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HKFIIIAO_01527 1.25e-66 - - - - - - - -
HKFIIIAO_01528 3.23e-58 - - - - - - - -
HKFIIIAO_01529 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKFIIIAO_01530 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HKFIIIAO_01531 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKFIIIAO_01532 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HKFIIIAO_01533 1.38e-156 - - - S - - - Domain of unknown function (DUF4767)
HKFIIIAO_01534 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HKFIIIAO_01535 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HKFIIIAO_01536 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HKFIIIAO_01537 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKFIIIAO_01538 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HKFIIIAO_01539 4.47e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HKFIIIAO_01540 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HKFIIIAO_01541 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HKFIIIAO_01542 2.53e-107 ypmB - - S - - - protein conserved in bacteria
HKFIIIAO_01543 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HKFIIIAO_01544 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HKFIIIAO_01545 5.39e-164 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HKFIIIAO_01547 1.34e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKFIIIAO_01548 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_01549 1.58e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKFIIIAO_01550 5.32e-109 - - - T - - - Universal stress protein family
HKFIIIAO_01551 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_01552 1.1e-117 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKFIIIAO_01553 2.48e-76 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKFIIIAO_01554 8.03e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_01555 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HKFIIIAO_01556 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKFIIIAO_01557 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HKFIIIAO_01558 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKFIIIAO_01560 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HKFIIIAO_01561 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_01562 4.45e-309 - - - P - - - Major Facilitator Superfamily
HKFIIIAO_01563 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HKFIIIAO_01564 9.19e-95 - - - S - - - SnoaL-like domain
HKFIIIAO_01565 9.63e-307 - - - M - - - Glycosyltransferase, group 2 family protein
HKFIIIAO_01566 3.46e-267 mccF - - V - - - LD-carboxypeptidase
HKFIIIAO_01567 6.74e-101 - - - K - - - Acetyltransferase (GNAT) domain
HKFIIIAO_01568 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
HKFIIIAO_01569 1.38e-232 - - - V - - - LD-carboxypeptidase
HKFIIIAO_01570 4.35e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HKFIIIAO_01571 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_01572 6.79e-249 - - - - - - - -
HKFIIIAO_01573 3.03e-186 - - - S - - - hydrolase activity, acting on ester bonds
HKFIIIAO_01574 8.53e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HKFIIIAO_01575 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HKFIIIAO_01576 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
HKFIIIAO_01577 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HKFIIIAO_01578 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKFIIIAO_01579 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKFIIIAO_01580 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKFIIIAO_01581 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HKFIIIAO_01582 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKFIIIAO_01583 2.01e-145 - - - G - - - Phosphoglycerate mutase family
HKFIIIAO_01584 7.75e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HKFIIIAO_01587 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HKFIIIAO_01588 2.08e-92 - - - S - - - LuxR family transcriptional regulator
HKFIIIAO_01589 3.42e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HKFIIIAO_01591 1.27e-115 - - - F - - - NUDIX domain
HKFIIIAO_01592 4.87e-205 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01593 2.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKFIIIAO_01594 0.0 FbpA - - K - - - Fibronectin-binding protein
HKFIIIAO_01595 8.39e-234 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKFIIIAO_01596 1.97e-87 - - - K - - - Transcriptional regulator
HKFIIIAO_01597 1.11e-205 - - - S - - - EDD domain protein, DegV family
HKFIIIAO_01598 2.03e-100 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HKFIIIAO_01599 1.96e-168 - - - S - - - Protein of unknown function (DUF975)
HKFIIIAO_01600 2.29e-36 - - - - - - - -
HKFIIIAO_01601 2.37e-65 - - - - - - - -
HKFIIIAO_01602 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
HKFIIIAO_01603 1.15e-244 pmrB - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_01605 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HKFIIIAO_01606 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HKFIIIAO_01607 1.05e-176 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HKFIIIAO_01608 7.45e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKFIIIAO_01609 2.79e-181 - - - - - - - -
HKFIIIAO_01610 7.79e-78 - - - - - - - -
HKFIIIAO_01611 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HKFIIIAO_01612 1.48e-278 - - - - - - - -
HKFIIIAO_01613 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKFIIIAO_01614 8.6e-31 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKFIIIAO_01615 1.17e-181 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKFIIIAO_01616 2.89e-273 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKFIIIAO_01617 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKFIIIAO_01618 3.29e-121 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKFIIIAO_01619 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_01620 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HKFIIIAO_01621 3.22e-87 - - - - - - - -
HKFIIIAO_01622 1.18e-310 - - - M - - - Glycosyl transferase family group 2
HKFIIIAO_01623 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKFIIIAO_01624 4.19e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
HKFIIIAO_01625 1.07e-43 - - - S - - - YozE SAM-like fold
HKFIIIAO_01626 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKFIIIAO_01627 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HKFIIIAO_01628 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HKFIIIAO_01629 5.43e-228 - - - K - - - Transcriptional regulator
HKFIIIAO_01630 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKFIIIAO_01631 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKFIIIAO_01632 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKFIIIAO_01633 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HKFIIIAO_01634 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKFIIIAO_01635 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKFIIIAO_01636 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HKFIIIAO_01637 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKFIIIAO_01638 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKFIIIAO_01639 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HKFIIIAO_01640 1.01e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKFIIIAO_01641 9.18e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKFIIIAO_01643 5.13e-292 XK27_05470 - - E - - - Methionine synthase
HKFIIIAO_01644 7.05e-219 cpsY - - K - - - Transcriptional regulator, LysR family
HKFIIIAO_01645 7e-208 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_01646 2.22e-169 - - - L - - - Helix-turn-helix domain
HKFIIIAO_01647 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HKFIIIAO_01648 3.53e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HKFIIIAO_01649 1.43e-251 XK27_00915 - - C - - - Luciferase-like monooxygenase
HKFIIIAO_01650 0.0 qacA - - EGP - - - Major Facilitator
HKFIIIAO_01651 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HKFIIIAO_01652 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HKFIIIAO_01653 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HKFIIIAO_01654 5.66e-207 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HKFIIIAO_01655 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HKFIIIAO_01656 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKFIIIAO_01657 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKFIIIAO_01658 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01659 6.46e-109 - - - - - - - -
HKFIIIAO_01660 1.27e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKFIIIAO_01661 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKFIIIAO_01662 7.48e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKFIIIAO_01663 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HKFIIIAO_01664 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKFIIIAO_01665 4.84e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HKFIIIAO_01666 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HKFIIIAO_01667 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HKFIIIAO_01668 1.25e-39 - - - M - - - Lysin motif
HKFIIIAO_01669 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKFIIIAO_01670 1.72e-245 - - - S - - - Helix-turn-helix domain
HKFIIIAO_01671 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKFIIIAO_01672 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKFIIIAO_01673 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKFIIIAO_01674 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKFIIIAO_01675 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKFIIIAO_01676 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HKFIIIAO_01677 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
HKFIIIAO_01678 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HKFIIIAO_01679 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HKFIIIAO_01680 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKFIIIAO_01681 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HKFIIIAO_01682 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
HKFIIIAO_01684 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKFIIIAO_01685 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HKFIIIAO_01686 1.09e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKFIIIAO_01687 6.85e-164 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HKFIIIAO_01688 1.75e-295 - - - M - - - O-Antigen ligase
HKFIIIAO_01689 5.09e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HKFIIIAO_01690 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_01691 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_01692 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKFIIIAO_01693 1.06e-69 - - - P - - - Rhodanese Homology Domain
HKFIIIAO_01694 6.11e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_01695 1.93e-266 - - - - - - - -
HKFIIIAO_01696 4.8e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HKFIIIAO_01697 1.02e-230 - - - C - - - Zinc-binding dehydrogenase
HKFIIIAO_01698 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HKFIIIAO_01699 1.27e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKFIIIAO_01700 1.32e-306 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HKFIIIAO_01701 4.38e-102 - - - K - - - Transcriptional regulator
HKFIIIAO_01702 7.53e-264 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKFIIIAO_01703 1.54e-137 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKFIIIAO_01704 2.33e-89 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKFIIIAO_01705 1.64e-126 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKFIIIAO_01706 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HKFIIIAO_01707 1.4e-137 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HKFIIIAO_01708 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
HKFIIIAO_01709 6.34e-90 - - - S - - - Protein of unknown function (DUF1722)
HKFIIIAO_01710 8.09e-146 - - - GM - - - epimerase
HKFIIIAO_01711 0.0 - - - S - - - Zinc finger, swim domain protein
HKFIIIAO_01712 1.51e-105 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_01713 5.58e-274 - - - S - - - membrane
HKFIIIAO_01714 2.15e-07 - - - K - - - transcriptional regulator
HKFIIIAO_01716 1.93e-35 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_01717 1.02e-219 - - - L - - - Integrase core domain
HKFIIIAO_01718 6.85e-140 - - - L - - - Bacterial dnaA protein
HKFIIIAO_01719 5.94e-24 - - - S - - - protein with an alpha beta hydrolase fold
HKFIIIAO_01720 1.31e-29 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_01721 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_01723 1.77e-145 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HKFIIIAO_01724 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HKFIIIAO_01725 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
HKFIIIAO_01726 8.81e-205 - - - S - - - Alpha beta hydrolase
HKFIIIAO_01727 1.39e-143 - - - GM - - - NmrA-like family
HKFIIIAO_01728 1.74e-101 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HKFIIIAO_01729 5.72e-207 - - - K - - - Transcriptional regulator
HKFIIIAO_01730 3.78e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HKFIIIAO_01732 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKFIIIAO_01733 1.51e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HKFIIIAO_01734 5.11e-266 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKFIIIAO_01735 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HKFIIIAO_01736 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_01738 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKFIIIAO_01739 5.53e-94 - - - K - - - MarR family
HKFIIIAO_01740 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
HKFIIIAO_01741 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
HKFIIIAO_01742 6.19e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01743 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKFIIIAO_01744 6.08e-253 - - - - - - - -
HKFIIIAO_01745 4.14e-190 - - - - - - - -
HKFIIIAO_01746 4.94e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01747 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HKFIIIAO_01748 7.07e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKFIIIAO_01749 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKFIIIAO_01750 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HKFIIIAO_01751 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HKFIIIAO_01752 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HKFIIIAO_01753 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKFIIIAO_01754 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HKFIIIAO_01755 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKFIIIAO_01756 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HKFIIIAO_01757 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HKFIIIAO_01758 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HKFIIIAO_01759 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKFIIIAO_01760 3.5e-164 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HKFIIIAO_01761 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKFIIIAO_01762 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKFIIIAO_01763 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKFIIIAO_01764 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKFIIIAO_01765 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKFIIIAO_01766 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HKFIIIAO_01767 4.01e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HKFIIIAO_01768 4.23e-210 - - - G - - - Fructosamine kinase
HKFIIIAO_01769 2.43e-150 yjcF - - J - - - HAD-hyrolase-like
HKFIIIAO_01770 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKFIIIAO_01771 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKFIIIAO_01772 2.56e-76 - - - - - - - -
HKFIIIAO_01773 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKFIIIAO_01774 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HKFIIIAO_01775 5.28e-146 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HKFIIIAO_01776 4.78e-65 - - - - - - - -
HKFIIIAO_01777 1.73e-67 - - - - - - - -
HKFIIIAO_01780 1.01e-158 int7 - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_01781 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKFIIIAO_01782 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKFIIIAO_01783 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKFIIIAO_01784 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HKFIIIAO_01785 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKFIIIAO_01786 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HKFIIIAO_01787 8.49e-266 pbpX2 - - V - - - Beta-lactamase
HKFIIIAO_01788 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKFIIIAO_01789 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HKFIIIAO_01790 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKFIIIAO_01791 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKFIIIAO_01792 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HKFIIIAO_01793 1.53e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HKFIIIAO_01794 8.94e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKFIIIAO_01795 2.41e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKFIIIAO_01796 1.47e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HKFIIIAO_01797 1.24e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKFIIIAO_01798 1.63e-121 - - - - - - - -
HKFIIIAO_01799 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKFIIIAO_01800 0.0 - - - G - - - Major Facilitator
HKFIIIAO_01801 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKFIIIAO_01802 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKFIIIAO_01803 3.28e-63 ylxQ - - J - - - ribosomal protein
HKFIIIAO_01804 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HKFIIIAO_01805 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HKFIIIAO_01806 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HKFIIIAO_01807 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKFIIIAO_01808 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKFIIIAO_01809 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HKFIIIAO_01810 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HKFIIIAO_01811 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKFIIIAO_01812 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKFIIIAO_01813 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HKFIIIAO_01814 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKFIIIAO_01815 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HKFIIIAO_01816 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HKFIIIAO_01817 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKFIIIAO_01818 5.67e-64 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HKFIIIAO_01819 2.11e-171 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HKFIIIAO_01820 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HKFIIIAO_01821 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HKFIIIAO_01822 7.68e-48 ynzC - - S - - - UPF0291 protein
HKFIIIAO_01823 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKFIIIAO_01824 7.8e-123 - - - - - - - -
HKFIIIAO_01825 1.56e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HKFIIIAO_01826 1.38e-98 - - - - - - - -
HKFIIIAO_01827 3.81e-87 - - - - - - - -
HKFIIIAO_01828 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HKFIIIAO_01829 2.19e-131 - - - L - - - Helix-turn-helix domain
HKFIIIAO_01830 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HKFIIIAO_01831 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_01832 3.64e-144 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_01833 3.06e-234 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_01834 1.96e-293 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HKFIIIAO_01836 3.33e-56 - - - S - - - Bacteriophage holin
HKFIIIAO_01837 1.46e-46 - - - S - - - Haemolysin XhlA
HKFIIIAO_01838 2.31e-257 - - - M - - - Glycosyl hydrolases family 25
HKFIIIAO_01839 9.89e-33 - - - - - - - -
HKFIIIAO_01840 3.51e-99 - - - - - - - -
HKFIIIAO_01842 1.17e-186 - - - - - - - -
HKFIIIAO_01843 0.0 - - - S - - - Phage minor structural protein
HKFIIIAO_01844 0.0 - - - S - - - Phage tail protein
HKFIIIAO_01845 0.0 - - - D - - - domain protein
HKFIIIAO_01846 5.71e-33 - - - - - - - -
HKFIIIAO_01847 1.58e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
HKFIIIAO_01848 1.59e-135 - - - S - - - Phage tail tube protein
HKFIIIAO_01849 7.47e-74 - - - S - - - Protein of unknown function (DUF806)
HKFIIIAO_01850 3.74e-85 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HKFIIIAO_01851 6.96e-76 - - - S - - - Phage head-tail joining protein
HKFIIIAO_01852 1.97e-66 - - - S - - - Phage gp6-like head-tail connector protein
HKFIIIAO_01853 1.86e-269 - - - S - - - peptidase activity
HKFIIIAO_01854 6e-166 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HKFIIIAO_01855 8.13e-283 - - - S - - - Phage portal protein
HKFIIIAO_01856 2.72e-34 - - - S - - - Protein of unknown function (DUF1056)
HKFIIIAO_01857 0.0 - - - S - - - Phage Terminase
HKFIIIAO_01858 1.29e-102 - - - S - - - Phage terminase, small subunit
HKFIIIAO_01859 5.72e-117 - - - L - - - HNH nucleases
HKFIIIAO_01862 4.83e-47 - - - S - - - Transcriptional regulator, RinA family
HKFIIIAO_01865 8.09e-235 - - - - - - - -
HKFIIIAO_01867 2.21e-50 - - - S - - - YopX protein
HKFIIIAO_01868 2.1e-17 - - - - - - - -
HKFIIIAO_01869 4.83e-61 - - - - - - - -
HKFIIIAO_01871 2.4e-186 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HKFIIIAO_01872 7.13e-42 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HKFIIIAO_01875 1.87e-24 - - - - - - - -
HKFIIIAO_01883 6.04e-87 - - - S - - - DNA binding
HKFIIIAO_01885 2.9e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKFIIIAO_01888 2e-51 - - - S - - - Membrane
HKFIIIAO_01894 8.67e-75 int3 - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_01895 1.75e-43 - - - - - - - -
HKFIIIAO_01896 6.34e-178 - - - Q - - - Methyltransferase
HKFIIIAO_01897 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HKFIIIAO_01898 6.75e-269 - - - EGP - - - Major facilitator Superfamily
HKFIIIAO_01899 3.58e-129 - - - K - - - Helix-turn-helix domain
HKFIIIAO_01900 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKFIIIAO_01901 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HKFIIIAO_01902 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HKFIIIAO_01903 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_01904 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKFIIIAO_01905 6.62e-62 - - - - - - - -
HKFIIIAO_01906 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKFIIIAO_01907 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HKFIIIAO_01908 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKFIIIAO_01909 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HKFIIIAO_01910 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HKFIIIAO_01911 4.34e-220 cps4J - - S - - - MatE
HKFIIIAO_01912 1.19e-88 cps4J - - S - - - MatE
HKFIIIAO_01913 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
HKFIIIAO_01914 1.91e-297 - - - - - - - -
HKFIIIAO_01915 9.2e-243 cps4G - - M - - - Glycosyltransferase Family 4
HKFIIIAO_01916 8.84e-137 cps4F - - M - - - Glycosyl transferases group 1
HKFIIIAO_01917 7.3e-86 cps4F - - M - - - Glycosyl transferases group 1
HKFIIIAO_01918 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
HKFIIIAO_01919 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HKFIIIAO_01920 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HKFIIIAO_01921 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
HKFIIIAO_01922 1.09e-33 epsB - - M - - - biosynthesis protein
HKFIIIAO_01923 1.22e-116 epsB - - M - - - biosynthesis protein
HKFIIIAO_01924 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKFIIIAO_01925 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_01926 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKFIIIAO_01927 5.12e-31 - - - - - - - -
HKFIIIAO_01928 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HKFIIIAO_01929 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HKFIIIAO_01930 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HKFIIIAO_01931 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKFIIIAO_01932 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKFIIIAO_01933 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKFIIIAO_01934 2.4e-203 - - - S - - - Tetratricopeptide repeat
HKFIIIAO_01935 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKFIIIAO_01936 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKFIIIAO_01937 4.48e-261 - - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_01938 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKFIIIAO_01939 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HKFIIIAO_01940 2.42e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HKFIIIAO_01941 4.44e-84 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HKFIIIAO_01942 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HKFIIIAO_01943 1.01e-115 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HKFIIIAO_01944 5.47e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HKFIIIAO_01945 3.01e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HKFIIIAO_01946 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKFIIIAO_01947 7.08e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HKFIIIAO_01948 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HKFIIIAO_01949 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKFIIIAO_01950 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HKFIIIAO_01951 0.0 - - - - - - - -
HKFIIIAO_01952 3.28e-245 icaA - - M - - - Glycosyl transferase family group 2
HKFIIIAO_01953 9.46e-70 icaA - - M - - - Glycosyl transferase family group 2
HKFIIIAO_01954 9.51e-135 - - - - - - - -
HKFIIIAO_01955 7.94e-195 - - - - - - - -
HKFIIIAO_01956 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HKFIIIAO_01957 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HKFIIIAO_01958 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HKFIIIAO_01959 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HKFIIIAO_01960 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HKFIIIAO_01961 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKFIIIAO_01962 8.65e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HKFIIIAO_01963 4.94e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HKFIIIAO_01964 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKFIIIAO_01965 6.45e-111 - - - - - - - -
HKFIIIAO_01966 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HKFIIIAO_01967 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKFIIIAO_01968 3.45e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HKFIIIAO_01969 2.16e-39 - - - - - - - -
HKFIIIAO_01970 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HKFIIIAO_01971 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKFIIIAO_01972 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKFIIIAO_01973 1.02e-155 - - - S - - - repeat protein
HKFIIIAO_01974 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HKFIIIAO_01975 0.0 - - - N - - - domain, Protein
HKFIIIAO_01976 4.97e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
HKFIIIAO_01977 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
HKFIIIAO_01978 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HKFIIIAO_01979 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HKFIIIAO_01980 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKFIIIAO_01981 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HKFIIIAO_01982 4.88e-276 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKFIIIAO_01983 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKFIIIAO_01984 7.74e-47 - - - - - - - -
HKFIIIAO_01985 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HKFIIIAO_01986 1.41e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKFIIIAO_01987 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKFIIIAO_01988 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HKFIIIAO_01989 2.06e-187 ylmH - - S - - - S4 domain protein
HKFIIIAO_01990 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HKFIIIAO_01991 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKFIIIAO_01992 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKFIIIAO_01993 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKFIIIAO_01994 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKFIIIAO_01995 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKFIIIAO_01996 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKFIIIAO_01997 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKFIIIAO_01998 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKFIIIAO_01999 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HKFIIIAO_02000 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKFIIIAO_02001 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HKFIIIAO_02002 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
HKFIIIAO_02003 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HKFIIIAO_02004 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HKFIIIAO_02005 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKFIIIAO_02006 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HKFIIIAO_02007 3.59e-301 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKFIIIAO_02009 1.3e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HKFIIIAO_02010 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKFIIIAO_02011 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HKFIIIAO_02012 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HKFIIIAO_02013 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HKFIIIAO_02014 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HKFIIIAO_02015 6.31e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKFIIIAO_02016 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKFIIIAO_02017 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HKFIIIAO_02018 2.24e-148 yjbH - - Q - - - Thioredoxin
HKFIIIAO_02019 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HKFIIIAO_02020 1.85e-263 coiA - - S ko:K06198 - ko00000 Competence protein
HKFIIIAO_02021 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKFIIIAO_02022 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKFIIIAO_02023 6.62e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
HKFIIIAO_02024 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HKFIIIAO_02044 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HKFIIIAO_02045 1.11e-84 - - - - - - - -
HKFIIIAO_02046 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HKFIIIAO_02047 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKFIIIAO_02048 8.38e-152 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HKFIIIAO_02049 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
HKFIIIAO_02050 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKFIIIAO_02051 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
HKFIIIAO_02052 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HKFIIIAO_02053 1.66e-150 - - - S - - - Calcineurin-like phosphoesterase
HKFIIIAO_02054 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKFIIIAO_02055 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKFIIIAO_02056 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HKFIIIAO_02058 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
HKFIIIAO_02059 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HKFIIIAO_02060 4.29e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HKFIIIAO_02061 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HKFIIIAO_02062 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HKFIIIAO_02063 2.57e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HKFIIIAO_02064 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKFIIIAO_02065 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HKFIIIAO_02066 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HKFIIIAO_02067 3.21e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
HKFIIIAO_02068 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HKFIIIAO_02069 8.96e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKFIIIAO_02070 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02071 1.6e-96 - - - - - - - -
HKFIIIAO_02072 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKFIIIAO_02073 1.9e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HKFIIIAO_02074 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKFIIIAO_02075 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKFIIIAO_02076 7.94e-114 ykuL - - S - - - (CBS) domain
HKFIIIAO_02077 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HKFIIIAO_02078 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKFIIIAO_02079 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HKFIIIAO_02080 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
HKFIIIAO_02081 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKFIIIAO_02082 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKFIIIAO_02083 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKFIIIAO_02084 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HKFIIIAO_02085 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKFIIIAO_02086 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HKFIIIAO_02087 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKFIIIAO_02088 3.72e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKFIIIAO_02089 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HKFIIIAO_02090 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKFIIIAO_02091 1.26e-61 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKFIIIAO_02092 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKFIIIAO_02093 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKFIIIAO_02094 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKFIIIAO_02095 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKFIIIAO_02096 2.83e-114 - - - - - - - -
HKFIIIAO_02097 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HKFIIIAO_02098 1.3e-91 - - - - - - - -
HKFIIIAO_02099 0.0 - - - L ko:K07487 - ko00000 Transposase
HKFIIIAO_02100 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKFIIIAO_02101 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKFIIIAO_02102 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HKFIIIAO_02103 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HKFIIIAO_02104 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKFIIIAO_02105 3.83e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HKFIIIAO_02106 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKFIIIAO_02107 4.71e-171 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HKFIIIAO_02108 0.0 ymfH - - S - - - Peptidase M16
HKFIIIAO_02109 9.74e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
HKFIIIAO_02110 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKFIIIAO_02111 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HKFIIIAO_02112 2.61e-148 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02113 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKFIIIAO_02114 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HKFIIIAO_02115 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKFIIIAO_02116 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HKFIIIAO_02117 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HKFIIIAO_02118 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HKFIIIAO_02119 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HKFIIIAO_02120 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKFIIIAO_02121 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKFIIIAO_02122 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKFIIIAO_02123 6.39e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HKFIIIAO_02124 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKFIIIAO_02125 2.59e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKFIIIAO_02127 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKFIIIAO_02128 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HKFIIIAO_02129 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKFIIIAO_02130 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
HKFIIIAO_02131 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HKFIIIAO_02132 2.6e-141 - - - S - - - Protein of unknown function (DUF1648)
HKFIIIAO_02133 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_02134 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HKFIIIAO_02135 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HKFIIIAO_02136 1.34e-52 - - - - - - - -
HKFIIIAO_02137 2.37e-107 uspA - - T - - - universal stress protein
HKFIIIAO_02138 8.1e-261 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HKFIIIAO_02139 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_02140 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HKFIIIAO_02141 3.78e-272 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HKFIIIAO_02142 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKFIIIAO_02143 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
HKFIIIAO_02144 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKFIIIAO_02145 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKFIIIAO_02146 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKFIIIAO_02147 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKFIIIAO_02148 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HKFIIIAO_02149 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HKFIIIAO_02150 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
HKFIIIAO_02151 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HKFIIIAO_02152 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HKFIIIAO_02153 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKFIIIAO_02154 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKFIIIAO_02155 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HKFIIIAO_02156 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKFIIIAO_02157 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKFIIIAO_02158 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKFIIIAO_02159 5.83e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKFIIIAO_02160 7.68e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKFIIIAO_02161 3.66e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKFIIIAO_02162 6.85e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HKFIIIAO_02163 1.44e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HKFIIIAO_02164 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKFIIIAO_02165 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKFIIIAO_02166 7.28e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKFIIIAO_02167 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKFIIIAO_02168 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKFIIIAO_02169 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HKFIIIAO_02170 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HKFIIIAO_02171 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HKFIIIAO_02172 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HKFIIIAO_02173 2.65e-245 ampC - - V - - - Beta-lactamase
HKFIIIAO_02174 2.1e-41 - - - - - - - -
HKFIIIAO_02175 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HKFIIIAO_02176 1.33e-77 - - - - - - - -
HKFIIIAO_02177 5.37e-182 - - - - - - - -
HKFIIIAO_02178 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKFIIIAO_02179 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02180 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
HKFIIIAO_02181 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
HKFIIIAO_02184 8.08e-40 - - - - - - - -
HKFIIIAO_02187 7.78e-76 - - - - - - - -
HKFIIIAO_02188 9.37e-53 - - - S - - - Phage gp6-like head-tail connector protein
HKFIIIAO_02191 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HKFIIIAO_02192 4.85e-257 - - - S - - - Phage portal protein
HKFIIIAO_02194 2.52e-305 terL - - S - - - overlaps another CDS with the same product name
HKFIIIAO_02195 2.57e-83 terL - - S - - - overlaps another CDS with the same product name
HKFIIIAO_02196 2.59e-107 - - - L - - - overlaps another CDS with the same product name
HKFIIIAO_02197 6.34e-90 - - - L - - - HNH endonuclease
HKFIIIAO_02198 3.37e-64 - - - S - - - Head-tail joining protein
HKFIIIAO_02199 1.73e-32 - - - - - - - -
HKFIIIAO_02200 4.64e-111 - - - - - - - -
HKFIIIAO_02201 0.0 - - - S - - - Virulence-associated protein E
HKFIIIAO_02202 9.32e-182 - - - L - - - DNA replication protein
HKFIIIAO_02204 1.96e-13 - - - - - - - -
HKFIIIAO_02207 3.87e-284 - - - L - - - Belongs to the 'phage' integrase family
HKFIIIAO_02208 1.28e-51 - - - - - - - -
HKFIIIAO_02209 1.09e-56 - - - - - - - -
HKFIIIAO_02210 1.27e-109 - - - K - - - MarR family
HKFIIIAO_02211 0.0 - - - D - - - nuclear chromosome segregation
HKFIIIAO_02212 0.0 inlJ - - M - - - MucBP domain
HKFIIIAO_02213 6.58e-24 - - - - - - - -
HKFIIIAO_02214 3.26e-24 - - - - - - - -
HKFIIIAO_02215 1.56e-22 - - - - - - - -
HKFIIIAO_02216 1.07e-26 - - - - - - - -
HKFIIIAO_02217 9.35e-24 - - - - - - - -
HKFIIIAO_02218 9.35e-24 - - - - - - - -
HKFIIIAO_02219 2.16e-26 - - - - - - - -
HKFIIIAO_02220 4.63e-24 - - - - - - - -
HKFIIIAO_02221 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HKFIIIAO_02222 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_02223 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02224 2.1e-33 - - - - - - - -
HKFIIIAO_02225 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HKFIIIAO_02226 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HKFIIIAO_02227 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HKFIIIAO_02228 0.0 yclK - - T - - - Histidine kinase
HKFIIIAO_02229 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HKFIIIAO_02230 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HKFIIIAO_02231 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HKFIIIAO_02232 3.62e-218 - - - EG - - - EamA-like transporter family
HKFIIIAO_02234 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
HKFIIIAO_02235 1.31e-64 - - - - - - - -
HKFIIIAO_02236 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HKFIIIAO_02237 8.05e-178 - - - F - - - NUDIX domain
HKFIIIAO_02238 2.68e-32 - - - - - - - -
HKFIIIAO_02240 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_02241 3.51e-222 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HKFIIIAO_02242 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HKFIIIAO_02243 2.29e-48 - - - - - - - -
HKFIIIAO_02244 1.11e-45 - - - - - - - -
HKFIIIAO_02245 2.58e-274 - - - T - - - diguanylate cyclase
HKFIIIAO_02246 0.0 - - - S - - - ABC transporter, ATP-binding protein
HKFIIIAO_02247 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HKFIIIAO_02248 1.59e-104 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKFIIIAO_02249 9.2e-62 - - - - - - - -
HKFIIIAO_02250 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HKFIIIAO_02251 4.37e-241 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKFIIIAO_02252 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
HKFIIIAO_02253 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HKFIIIAO_02254 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HKFIIIAO_02255 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HKFIIIAO_02256 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_02257 7.03e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKFIIIAO_02258 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02259 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HKFIIIAO_02260 9.51e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HKFIIIAO_02261 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
HKFIIIAO_02262 4.99e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKFIIIAO_02263 4.48e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKFIIIAO_02264 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HKFIIIAO_02265 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKFIIIAO_02266 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKFIIIAO_02267 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKFIIIAO_02268 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKFIIIAO_02269 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HKFIIIAO_02270 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKFIIIAO_02271 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKFIIIAO_02272 3.65e-272 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKFIIIAO_02273 3.2e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HKFIIIAO_02274 3.72e-283 ysaA - - V - - - RDD family
HKFIIIAO_02275 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HKFIIIAO_02276 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
HKFIIIAO_02277 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
HKFIIIAO_02278 2.49e-190 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_02279 4.54e-126 - - - J - - - glyoxalase III activity
HKFIIIAO_02280 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKFIIIAO_02281 9.88e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKFIIIAO_02282 1.45e-46 - - - - - - - -
HKFIIIAO_02283 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
HKFIIIAO_02284 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HKFIIIAO_02285 0.0 - - - M - - - domain protein
HKFIIIAO_02286 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
HKFIIIAO_02287 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKFIIIAO_02288 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HKFIIIAO_02289 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HKFIIIAO_02290 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_02291 2.35e-247 - - - S - - - domain, Protein
HKFIIIAO_02292 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
HKFIIIAO_02293 2.57e-128 - - - C - - - Nitroreductase family
HKFIIIAO_02294 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HKFIIIAO_02295 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKFIIIAO_02296 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_02297 1.48e-201 ccpB - - K - - - lacI family
HKFIIIAO_02298 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
HKFIIIAO_02299 9.95e-92 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HKFIIIAO_02300 4.07e-217 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKFIIIAO_02301 8.76e-49 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HKFIIIAO_02302 9.51e-49 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HKFIIIAO_02303 8.97e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HKFIIIAO_02304 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HKFIIIAO_02305 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKFIIIAO_02306 9.38e-139 pncA - - Q - - - Isochorismatase family
HKFIIIAO_02307 2.66e-172 - - - - - - - -
HKFIIIAO_02308 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_02309 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HKFIIIAO_02310 7.2e-61 - - - S - - - Enterocin A Immunity
HKFIIIAO_02311 4.62e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
HKFIIIAO_02312 0.0 pepF2 - - E - - - Oligopeptidase F
HKFIIIAO_02313 1.4e-95 - - - K - - - Transcriptional regulator
HKFIIIAO_02314 1.08e-209 - - - - - - - -
HKFIIIAO_02316 3.68e-77 - - - - - - - -
HKFIIIAO_02317 4.83e-64 - - - - - - - -
HKFIIIAO_02318 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_02319 5.82e-89 - - - - - - - -
HKFIIIAO_02320 1.97e-185 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HKFIIIAO_02321 9.89e-74 ytpP - - CO - - - Thioredoxin
HKFIIIAO_02322 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HKFIIIAO_02323 3.89e-62 - - - - - - - -
HKFIIIAO_02324 1.57e-71 - - - - - - - -
HKFIIIAO_02325 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
HKFIIIAO_02326 4.05e-98 - - - - - - - -
HKFIIIAO_02327 4.15e-78 - - - - - - - -
HKFIIIAO_02328 1.73e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HKFIIIAO_02329 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HKFIIIAO_02330 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKFIIIAO_02331 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKFIIIAO_02332 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKFIIIAO_02333 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKFIIIAO_02334 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HKFIIIAO_02335 1.02e-102 uspA3 - - T - - - universal stress protein
HKFIIIAO_02336 5.88e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HKFIIIAO_02337 3.77e-24 - - - - - - - -
HKFIIIAO_02338 1.09e-55 - - - S - - - zinc-ribbon domain
HKFIIIAO_02339 2.12e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HKFIIIAO_02340 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKFIIIAO_02341 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HKFIIIAO_02342 5.31e-285 - - - M - - - Glycosyl transferases group 1
HKFIIIAO_02343 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HKFIIIAO_02344 4.74e-208 - - - S - - - Putative esterase
HKFIIIAO_02345 3.53e-169 - - - K - - - Transcriptional regulator
HKFIIIAO_02346 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKFIIIAO_02347 1.74e-178 - - - - - - - -
HKFIIIAO_02348 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFIIIAO_02349 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HKFIIIAO_02350 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
HKFIIIAO_02351 1.55e-79 - - - - - - - -
HKFIIIAO_02352 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKFIIIAO_02353 2.97e-76 - - - - - - - -
HKFIIIAO_02354 0.0 yhdP - - S - - - Transporter associated domain
HKFIIIAO_02355 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HKFIIIAO_02356 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HKFIIIAO_02357 2.03e-271 yttB - - EGP - - - Major Facilitator
HKFIIIAO_02358 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02359 1.27e-219 - - - C - - - Zinc-binding dehydrogenase
HKFIIIAO_02360 4.71e-74 - - - S - - - SdpI/YhfL protein family
HKFIIIAO_02361 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKFIIIAO_02362 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HKFIIIAO_02363 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKFIIIAO_02364 1.21e-183 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKFIIIAO_02365 3.59e-26 - - - - - - - -
HKFIIIAO_02366 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HKFIIIAO_02367 5.73e-208 mleR - - K - - - LysR family
HKFIIIAO_02368 1.29e-148 - - - GM - - - NAD(P)H-binding
HKFIIIAO_02369 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
HKFIIIAO_02370 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HKFIIIAO_02371 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKFIIIAO_02372 1.04e-211 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HKFIIIAO_02373 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKFIIIAO_02374 1.55e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKFIIIAO_02375 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKFIIIAO_02376 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKFIIIAO_02377 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HKFIIIAO_02378 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKFIIIAO_02379 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HKFIIIAO_02380 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKFIIIAO_02381 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HKFIIIAO_02382 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HKFIIIAO_02383 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HKFIIIAO_02384 2.24e-206 - - - GM - - - NmrA-like family
HKFIIIAO_02385 1.25e-199 - - - T - - - EAL domain
HKFIIIAO_02386 3.73e-121 - - - - - - - -
HKFIIIAO_02387 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HKFIIIAO_02388 6.93e-162 - - - E - - - Methionine synthase
HKFIIIAO_02389 9.06e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HKFIIIAO_02390 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HKFIIIAO_02391 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKFIIIAO_02392 2.97e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HKFIIIAO_02393 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKFIIIAO_02394 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFIIIAO_02395 1.63e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFIIIAO_02396 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKFIIIAO_02397 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HKFIIIAO_02398 5.8e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKFIIIAO_02399 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKFIIIAO_02400 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HKFIIIAO_02401 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HKFIIIAO_02402 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HKFIIIAO_02403 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKFIIIAO_02404 3.44e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HKFIIIAO_02405 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_02406 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HKFIIIAO_02407 8.34e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02408 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKFIIIAO_02409 4.76e-56 - - - - - - - -
HKFIIIAO_02410 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HKFIIIAO_02411 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02412 3.41e-190 - - - - - - - -
HKFIIIAO_02413 2.7e-104 usp5 - - T - - - universal stress protein
HKFIIIAO_02414 1.08e-47 - - - - - - - -
HKFIIIAO_02415 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HKFIIIAO_02416 1.76e-114 - - - - - - - -
HKFIIIAO_02417 4.87e-66 - - - - - - - -
HKFIIIAO_02418 4.79e-13 - - - - - - - -
HKFIIIAO_02419 8.32e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HKFIIIAO_02420 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HKFIIIAO_02421 4.34e-151 - - - - - - - -
HKFIIIAO_02422 1.21e-69 - - - - - - - -
HKFIIIAO_02424 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKFIIIAO_02425 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HKFIIIAO_02426 1.33e-185 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKFIIIAO_02427 4.72e-40 - - - S - - - Pentapeptide repeats (8 copies)
HKFIIIAO_02428 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKFIIIAO_02429 3.24e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HKFIIIAO_02430 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HKFIIIAO_02431 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HKFIIIAO_02432 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HKFIIIAO_02433 9.97e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HKFIIIAO_02434 3.23e-242 - - - S - - - Sterol carrier protein domain
HKFIIIAO_02435 3.26e-262 - - - EGP - - - Transmembrane secretion effector
HKFIIIAO_02436 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HKFIIIAO_02437 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKFIIIAO_02438 2.13e-152 - - - K - - - Transcriptional regulator
HKFIIIAO_02439 1.32e-231 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_02440 3.83e-107 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKFIIIAO_02441 9.43e-46 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKFIIIAO_02442 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HKFIIIAO_02443 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKFIIIAO_02444 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKFIIIAO_02445 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HKFIIIAO_02446 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKFIIIAO_02447 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HKFIIIAO_02448 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HKFIIIAO_02449 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HKFIIIAO_02450 7.63e-107 - - - - - - - -
HKFIIIAO_02451 5.06e-196 - - - S - - - hydrolase
HKFIIIAO_02452 2.05e-233 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKFIIIAO_02453 1.2e-107 - - - EG - - - EamA-like transporter family
HKFIIIAO_02454 2.25e-73 - - - EG - - - EamA-like transporter family
HKFIIIAO_02455 5.85e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKFIIIAO_02456 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HKFIIIAO_02457 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_02458 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HKFIIIAO_02459 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HKFIIIAO_02460 0.0 - - - M - - - Domain of unknown function (DUF5011)
HKFIIIAO_02461 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKFIIIAO_02462 4.3e-44 - - - - - - - -
HKFIIIAO_02463 2.38e-164 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HKFIIIAO_02464 3.49e-197 - - - L ko:K07482 - ko00000 Integrase core domain
HKFIIIAO_02465 0.0 ycaM - - E - - - amino acid
HKFIIIAO_02466 2.45e-101 - - - K - - - Winged helix DNA-binding domain
HKFIIIAO_02467 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HKFIIIAO_02468 1.2e-206 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HKFIIIAO_02469 6.19e-208 - - - K - - - Transcriptional regulator
HKFIIIAO_02471 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HKFIIIAO_02472 2.05e-110 - - - S - - - Pfam:DUF3816
HKFIIIAO_02473 3.47e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKFIIIAO_02474 1.27e-143 - - - - - - - -
HKFIIIAO_02475 1.08e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HKFIIIAO_02476 9.06e-184 - - - S - - - Peptidase_C39 like family
HKFIIIAO_02477 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HKFIIIAO_02478 1.95e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HKFIIIAO_02479 1.1e-187 - - - KT - - - helix_turn_helix, mercury resistance
HKFIIIAO_02480 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKFIIIAO_02481 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HKFIIIAO_02482 1.4e-239 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKFIIIAO_02483 2.91e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02484 2.27e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HKFIIIAO_02485 8.13e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HKFIIIAO_02486 8.37e-126 ywjB - - H - - - RibD C-terminal domain
HKFIIIAO_02487 8.02e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKFIIIAO_02488 9.01e-155 - - - S - - - Membrane
HKFIIIAO_02489 3.49e-198 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HKFIIIAO_02490 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HKFIIIAO_02491 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_02492 1.99e-160 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HKFIIIAO_02493 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HKFIIIAO_02494 2.33e-103 - - - S - - - Domain of unknown function (DUF4811)
HKFIIIAO_02495 7.96e-127 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKFIIIAO_02496 4.38e-222 - - - S - - - Conserved hypothetical protein 698
HKFIIIAO_02497 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HKFIIIAO_02498 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKFIIIAO_02499 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_02501 9.92e-88 - - - M - - - LysM domain
HKFIIIAO_02502 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HKFIIIAO_02503 9.97e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02504 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKFIIIAO_02505 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_02506 6.7e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HKFIIIAO_02507 4.77e-100 yphH - - S - - - Cupin domain
HKFIIIAO_02508 5.19e-103 - - - K - - - transcriptional regulator, MerR family
HKFIIIAO_02509 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKFIIIAO_02510 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKFIIIAO_02511 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02513 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKFIIIAO_02514 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKFIIIAO_02515 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKFIIIAO_02517 4.86e-111 - - - - - - - -
HKFIIIAO_02518 1.04e-110 yvbK - - K - - - GNAT family
HKFIIIAO_02519 9.76e-50 - - - - - - - -
HKFIIIAO_02520 2.81e-64 - - - - - - - -
HKFIIIAO_02521 1.5e-142 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HKFIIIAO_02522 6.09e-83 - - - S - - - Domain of unknown function (DUF4440)
HKFIIIAO_02523 6.13e-200 - - - K - - - LysR substrate binding domain
HKFIIIAO_02524 1.52e-135 - - - GM - - - NAD(P)H-binding
HKFIIIAO_02525 1.66e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HKFIIIAO_02526 1.18e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HKFIIIAO_02527 1.28e-45 - - - - - - - -
HKFIIIAO_02528 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
HKFIIIAO_02529 2.09e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HKFIIIAO_02530 5.89e-161 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HKFIIIAO_02531 1.03e-40 - - - - - - - -
HKFIIIAO_02532 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_02533 5.29e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HKFIIIAO_02534 2.33e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HKFIIIAO_02535 1.07e-131 - - - M - - - Protein of unknown function (DUF3737)
HKFIIIAO_02536 1.8e-249 - - - C - - - Aldo/keto reductase family
HKFIIIAO_02538 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02539 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02540 6.27e-316 - - - EGP - - - Major Facilitator
HKFIIIAO_02544 1.03e-314 yhgE - - V ko:K01421 - ko00000 domain protein
HKFIIIAO_02545 3.01e-124 - - - K - - - Transcriptional regulator (TetR family)
HKFIIIAO_02546 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_02547 4.88e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HKFIIIAO_02548 7.08e-68 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HKFIIIAO_02549 2.2e-45 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HKFIIIAO_02550 1.24e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKFIIIAO_02551 3.27e-171 - - - M - - - Phosphotransferase enzyme family
HKFIIIAO_02552 3.18e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKFIIIAO_02553 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HKFIIIAO_02554 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKFIIIAO_02555 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HKFIIIAO_02556 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HKFIIIAO_02557 9.48e-265 - - - EGP - - - Major facilitator Superfamily
HKFIIIAO_02558 7.97e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_02559 2.33e-296 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HKFIIIAO_02560 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HKFIIIAO_02561 2.85e-206 - - - I - - - alpha/beta hydrolase fold
HKFIIIAO_02562 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HKFIIIAO_02563 0.0 - - - - - - - -
HKFIIIAO_02564 2e-52 - - - S - - - Cytochrome B5
HKFIIIAO_02565 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKFIIIAO_02566 1.11e-65 - - - T - - - Diguanylate cyclase, GGDEF domain
HKFIIIAO_02567 5.92e-193 - - - T - - - Diguanylate cyclase, GGDEF domain
HKFIIIAO_02568 1.63e-162 - - - T - - - Putative diguanylate phosphodiesterase
HKFIIIAO_02569 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKFIIIAO_02570 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HKFIIIAO_02571 1.56e-108 - - - - - - - -
HKFIIIAO_02572 6.98e-95 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKFIIIAO_02573 3.08e-241 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKFIIIAO_02574 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKFIIIAO_02575 7.16e-30 - - - - - - - -
HKFIIIAO_02576 6.24e-130 - - - - - - - -
HKFIIIAO_02577 3.46e-210 - - - K - - - LysR substrate binding domain
HKFIIIAO_02578 1.85e-311 - - - P - - - Sodium:sulfate symporter transmembrane region
HKFIIIAO_02579 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKFIIIAO_02580 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HKFIIIAO_02581 1.61e-183 - - - S - - - zinc-ribbon domain
HKFIIIAO_02583 4.29e-50 - - - - - - - -
HKFIIIAO_02584 1.73e-170 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HKFIIIAO_02585 2.35e-231 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HKFIIIAO_02586 0.0 - - - I - - - acetylesterase activity
HKFIIIAO_02587 6.55e-295 - - - M - - - Collagen binding domain
HKFIIIAO_02588 8.08e-205 yicL - - EG - - - EamA-like transporter family
HKFIIIAO_02589 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
HKFIIIAO_02590 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HKFIIIAO_02591 4.68e-141 - - - K - - - Transcriptional regulator C-terminal region
HKFIIIAO_02592 1.85e-51 - - - K - - - HxlR-like helix-turn-helix
HKFIIIAO_02593 4.54e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HKFIIIAO_02594 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
HKFIIIAO_02595 9.86e-117 - - - - - - - -
HKFIIIAO_02596 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HKFIIIAO_02597 7.39e-121 - - - K - - - Transcriptional regulator, MarR family
HKFIIIAO_02598 5.85e-204 ccpB - - K - - - lacI family
HKFIIIAO_02599 2.21e-154 yceE - - S - - - haloacid dehalogenase-like hydrolase
HKFIIIAO_02600 3.29e-153 ydgI3 - - C - - - Nitroreductase family
HKFIIIAO_02601 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HKFIIIAO_02602 4.21e-150 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKFIIIAO_02603 1.01e-198 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKFIIIAO_02604 5.98e-217 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HKFIIIAO_02605 0.0 - - - - - - - -
HKFIIIAO_02606 4.71e-81 - - - - - - - -
HKFIIIAO_02607 9.55e-243 - - - S - - - Cell surface protein
HKFIIIAO_02608 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02609 5.06e-82 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HKFIIIAO_02610 1.09e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HKFIIIAO_02611 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02612 1.74e-178 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HKFIIIAO_02613 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HKFIIIAO_02614 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HKFIIIAO_02615 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HKFIIIAO_02617 1.15e-43 - - - - - - - -
HKFIIIAO_02618 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
HKFIIIAO_02619 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HKFIIIAO_02620 3.35e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_02621 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKFIIIAO_02622 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
HKFIIIAO_02623 7.03e-62 - - - - - - - -
HKFIIIAO_02624 1.81e-150 - - - S - - - SNARE associated Golgi protein
HKFIIIAO_02625 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HKFIIIAO_02626 7.89e-124 - - - P - - - Cadmium resistance transporter
HKFIIIAO_02627 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02628 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HKFIIIAO_02629 2.03e-84 - - - - - - - -
HKFIIIAO_02630 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HKFIIIAO_02631 1.21e-73 - - - - - - - -
HKFIIIAO_02632 1.24e-194 - - - K - - - Helix-turn-helix domain
HKFIIIAO_02633 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKFIIIAO_02634 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKFIIIAO_02635 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_02636 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKFIIIAO_02637 7.8e-238 - - - GM - - - Male sterility protein
HKFIIIAO_02638 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02639 2.18e-99 - - - M - - - LysM domain
HKFIIIAO_02640 1.44e-128 - - - M - - - Lysin motif
HKFIIIAO_02641 1.4e-138 - - - S - - - SdpI/YhfL protein family
HKFIIIAO_02642 1.58e-72 nudA - - S - - - ASCH
HKFIIIAO_02643 2.74e-210 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKFIIIAO_02644 1.41e-118 - - - - - - - -
HKFIIIAO_02645 6.68e-156 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HKFIIIAO_02646 1.22e-272 - - - T - - - diguanylate cyclase
HKFIIIAO_02647 4.65e-91 - - - S - - - Psort location Cytoplasmic, score
HKFIIIAO_02648 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HKFIIIAO_02649 1.43e-57 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HKFIIIAO_02650 6.88e-151 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HKFIIIAO_02651 2.66e-38 - - - - - - - -
HKFIIIAO_02652 1e-62 adhR - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02653 1.58e-47 - - - C - - - Flavodoxin
HKFIIIAO_02654 1.2e-208 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HKFIIIAO_02655 2.62e-173 - - - C - - - Aldo/keto reductase family
HKFIIIAO_02656 7.53e-102 - - - GM - - - NmrA-like family
HKFIIIAO_02657 1.91e-44 - - - C - - - Flavodoxin
HKFIIIAO_02658 0.0 - - - L ko:K07487 - ko00000 Transposase
HKFIIIAO_02660 6.61e-77 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_02661 1e-98 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
HKFIIIAO_02662 1.56e-56 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02663 1.66e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HKFIIIAO_02664 5.26e-96 - - - - - - - -
HKFIIIAO_02665 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_02666 2.18e-221 - - - C - - - C4-dicarboxylate transmembrane transporter activity
HKFIIIAO_02667 2.15e-151 - - - GM - - - NAD(P)H-binding
HKFIIIAO_02668 1.37e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HKFIIIAO_02669 6.7e-102 yphH - - S - - - Cupin domain
HKFIIIAO_02670 3.55e-79 - - - I - - - sulfurtransferase activity
HKFIIIAO_02671 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
HKFIIIAO_02672 2.4e-151 - - - GM - - - NAD(P)H-binding
HKFIIIAO_02673 2.31e-277 - - - - - - - -
HKFIIIAO_02674 3.5e-308 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02675 1.45e-97 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02676 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02677 3.61e-287 amd - - E - - - Peptidase family M20/M25/M40
HKFIIIAO_02678 2.96e-209 yhxD - - IQ - - - KR domain
HKFIIIAO_02680 1.97e-92 - - - - - - - -
HKFIIIAO_02681 2.47e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_02682 0.0 - - - E - - - Amino Acid
HKFIIIAO_02683 1.67e-86 lysM - - M - - - LysM domain
HKFIIIAO_02684 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HKFIIIAO_02685 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HKFIIIAO_02686 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HKFIIIAO_02687 1.49e-58 - - - S - - - Cupredoxin-like domain
HKFIIIAO_02688 1.36e-84 - - - S - - - Cupredoxin-like domain
HKFIIIAO_02689 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKFIIIAO_02690 8.55e-203 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKFIIIAO_02691 2.81e-181 - - - K - - - Helix-turn-helix domain
HKFIIIAO_02692 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HKFIIIAO_02693 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKFIIIAO_02694 0.0 - - - - - - - -
HKFIIIAO_02695 2.69e-99 - - - - - - - -
HKFIIIAO_02696 5.14e-246 - - - S - - - Cell surface protein
HKFIIIAO_02697 3.48e-136 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02698 1.55e-224 - - - C - - - Alcohol dehydrogenase GroES-like domain
HKFIIIAO_02699 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
HKFIIIAO_02700 3.89e-148 - - - S - - - GyrI-like small molecule binding domain
HKFIIIAO_02701 7.66e-237 ynjC - - S - - - Cell surface protein
HKFIIIAO_02702 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02703 1.47e-83 - - - - - - - -
HKFIIIAO_02704 3.5e-302 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HKFIIIAO_02705 4.13e-157 - - - - - - - -
HKFIIIAO_02706 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
HKFIIIAO_02707 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HKFIIIAO_02708 1.81e-272 - - - EGP - - - Major Facilitator
HKFIIIAO_02709 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HKFIIIAO_02710 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HKFIIIAO_02711 1.27e-170 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HKFIIIAO_02712 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKFIIIAO_02713 1.03e-126 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02714 6.24e-215 - - - GM - - - NmrA-like family
HKFIIIAO_02715 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HKFIIIAO_02716 0.0 - - - M - - - Glycosyl hydrolases family 25
HKFIIIAO_02717 1.23e-54 - - - M - - - Glycosyl hydrolases family 25
HKFIIIAO_02718 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
HKFIIIAO_02719 1.36e-58 - - - K - - - HxlR-like helix-turn-helix
HKFIIIAO_02720 3.27e-170 - - - S - - - KR domain
HKFIIIAO_02721 1.66e-125 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02722 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HKFIIIAO_02723 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
HKFIIIAO_02724 1.33e-227 ydhF - - S - - - Aldo keto reductase
HKFIIIAO_02725 0.0 yfjF - - U - - - Sugar (and other) transporter
HKFIIIAO_02726 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02727 3.35e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HKFIIIAO_02728 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKFIIIAO_02729 4.27e-227 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKFIIIAO_02730 1.92e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKFIIIAO_02731 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02732 7.95e-201 - - - GM - - - NmrA-like family
HKFIIIAO_02733 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKFIIIAO_02734 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HKFIIIAO_02735 1.5e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HKFIIIAO_02736 6.41e-84 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02737 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HKFIIIAO_02738 1.07e-115 - - - S - - - Bacterial protein of unknown function (DUF916)
HKFIIIAO_02739 3.25e-96 - - - S - - - Bacterial protein of unknown function (DUF916)
HKFIIIAO_02740 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02741 1.6e-261 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HKFIIIAO_02742 6.88e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02743 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKFIIIAO_02744 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HKFIIIAO_02745 1.85e-201 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HKFIIIAO_02746 1.06e-205 - - - K - - - LysR substrate binding domain
HKFIIIAO_02747 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HKFIIIAO_02748 0.0 - - - S - - - MucBP domain
HKFIIIAO_02749 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HKFIIIAO_02750 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
HKFIIIAO_02751 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKFIIIAO_02752 7.36e-316 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_02753 2.09e-85 - - - - - - - -
HKFIIIAO_02754 5.15e-16 - - - - - - - -
HKFIIIAO_02755 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HKFIIIAO_02756 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
HKFIIIAO_02757 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
HKFIIIAO_02758 1.25e-171 - - - L - - - PFAM transposase, IS4 family protein
HKFIIIAO_02759 2.23e-279 - - - S - - - Membrane
HKFIIIAO_02760 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
HKFIIIAO_02761 1.31e-139 yoaZ - - S - - - intracellular protease amidase
HKFIIIAO_02762 2.33e-56 - - - K - - - HxlR-like helix-turn-helix
HKFIIIAO_02763 3.07e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_02764 2e-62 - - - K - - - Helix-turn-helix domain
HKFIIIAO_02765 1.92e-115 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKFIIIAO_02766 2.5e-66 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKFIIIAO_02767 7.85e-114 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02768 6.79e-53 - - - - - - - -
HKFIIIAO_02769 2.06e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKFIIIAO_02770 1.6e-233 ydbI - - K - - - AI-2E family transporter
HKFIIIAO_02771 9.28e-271 xylR - - GK - - - ROK family
HKFIIIAO_02772 2.92e-143 - - - - - - - -
HKFIIIAO_02773 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HKFIIIAO_02774 3.32e-210 - - - - - - - -
HKFIIIAO_02775 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
HKFIIIAO_02776 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
HKFIIIAO_02777 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
HKFIIIAO_02778 5.61e-98 - - - S - - - Psort location Cytoplasmic, score
HKFIIIAO_02779 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_02780 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_02781 5.94e-40 - - - - - - - -
HKFIIIAO_02782 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
HKFIIIAO_02783 5.93e-73 - - - S - - - branched-chain amino acid
HKFIIIAO_02784 4.83e-166 - - - E - - - branched-chain amino acid
HKFIIIAO_02785 6.77e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HKFIIIAO_02786 3.61e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HKFIIIAO_02787 5.61e-273 hpk31 - - T - - - Histidine kinase
HKFIIIAO_02788 1.14e-159 vanR - - K - - - response regulator
HKFIIIAO_02789 1.39e-160 - - - S - - - Protein of unknown function (DUF1275)
HKFIIIAO_02790 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKFIIIAO_02791 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKFIIIAO_02792 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HKFIIIAO_02793 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKFIIIAO_02794 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HKFIIIAO_02795 7.16e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKFIIIAO_02796 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HKFIIIAO_02797 8.63e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKFIIIAO_02798 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HKFIIIAO_02799 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HKFIIIAO_02800 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HKFIIIAO_02801 1.49e-188 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_02802 3.36e-216 - - - K - - - LysR substrate binding domain
HKFIIIAO_02803 2.07e-302 - - - EK - - - Aminotransferase, class I
HKFIIIAO_02804 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HKFIIIAO_02805 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKFIIIAO_02806 1.74e-175 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02807 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HKFIIIAO_02808 1.07e-127 - - - KT - - - response to antibiotic
HKFIIIAO_02809 2.86e-68 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HKFIIIAO_02810 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
HKFIIIAO_02811 1.13e-200 - - - S - - - Putative adhesin
HKFIIIAO_02812 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKFIIIAO_02813 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKFIIIAO_02814 6.12e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HKFIIIAO_02815 3.73e-263 - - - S - - - DUF218 domain
HKFIIIAO_02816 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HKFIIIAO_02817 2.93e-151 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKFIIIAO_02818 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKFIIIAO_02819 6.26e-101 - - - - - - - -
HKFIIIAO_02820 2.69e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HKFIIIAO_02821 3.54e-190 - - - S - - - haloacid dehalogenase-like hydrolase
HKFIIIAO_02822 2.24e-116 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HKFIIIAO_02823 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
HKFIIIAO_02824 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
HKFIIIAO_02825 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKFIIIAO_02826 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
HKFIIIAO_02827 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKFIIIAO_02828 4.08e-101 - - - K - - - MerR family regulatory protein
HKFIIIAO_02829 7.54e-200 - - - GM - - - NmrA-like family
HKFIIIAO_02830 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKFIIIAO_02831 5.08e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HKFIIIAO_02833 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
HKFIIIAO_02834 3.43e-303 - - - S - - - module of peptide synthetase
HKFIIIAO_02835 1.78e-139 - - - - - - - -
HKFIIIAO_02836 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HKFIIIAO_02837 1.23e-53 - - - S - - - Enterocin A Immunity
HKFIIIAO_02838 3.07e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_02839 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
HKFIIIAO_02840 4.05e-170 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HKFIIIAO_02841 1.29e-31 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HKFIIIAO_02842 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HKFIIIAO_02843 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HKFIIIAO_02844 6.79e-163 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HKFIIIAO_02845 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
HKFIIIAO_02846 4.22e-34 - - - - - - - -
HKFIIIAO_02847 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HKFIIIAO_02848 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HKFIIIAO_02849 6.72e-209 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HKFIIIAO_02850 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
HKFIIIAO_02851 1.01e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HKFIIIAO_02852 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HKFIIIAO_02853 2.05e-72 - - - S - - - Enterocin A Immunity
HKFIIIAO_02854 3.66e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKFIIIAO_02855 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKFIIIAO_02856 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKFIIIAO_02857 6.97e-134 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HKFIIIAO_02858 4.29e-33 amiF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HKFIIIAO_02859 1.84e-241 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKFIIIAO_02860 2.53e-200 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKFIIIAO_02861 0.0 amiC - - U ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKFIIIAO_02862 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HKFIIIAO_02863 5.9e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKFIIIAO_02864 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKFIIIAO_02866 4.62e-107 - - - - - - - -
HKFIIIAO_02867 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_02868 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HKFIIIAO_02870 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HKFIIIAO_02871 3.06e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKFIIIAO_02872 1.89e-110 ydbI - - K - - - AI-2E family transporter
HKFIIIAO_02873 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_02874 1.59e-98 ydbI - - K - - - AI-2E family transporter
HKFIIIAO_02875 1.68e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HKFIIIAO_02876 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HKFIIIAO_02877 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HKFIIIAO_02878 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HKFIIIAO_02879 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HKFIIIAO_02880 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HKFIIIAO_02881 6.62e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_02883 8.03e-28 - - - - - - - -
HKFIIIAO_02884 1.31e-122 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HKFIIIAO_02885 1.37e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HKFIIIAO_02886 3.59e-130 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HKFIIIAO_02887 3.42e-313 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKFIIIAO_02888 1.04e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HKFIIIAO_02889 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKFIIIAO_02890 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKFIIIAO_02891 4.08e-107 cvpA - - S - - - Colicin V production protein
HKFIIIAO_02892 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKFIIIAO_02893 8.83e-317 - - - EGP - - - Major Facilitator
HKFIIIAO_02895 4.54e-54 - - - - - - - -
HKFIIIAO_02896 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HKFIIIAO_02897 3.74e-125 - - - V - - - VanZ like family
HKFIIIAO_02898 1.26e-247 - - - V - - - Beta-lactamase
HKFIIIAO_02899 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HKFIIIAO_02900 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKFIIIAO_02901 8.93e-71 - - - S - - - Pfam:DUF59
HKFIIIAO_02902 6.07e-223 ydhF - - S - - - Aldo keto reductase
HKFIIIAO_02903 2.42e-127 - - - FG - - - HIT domain
HKFIIIAO_02904 9.9e-49 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HKFIIIAO_02905 4.29e-101 - - - - - - - -
HKFIIIAO_02906 8.79e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HKFIIIAO_02907 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HKFIIIAO_02908 0.0 cadA - - P - - - P-type ATPase
HKFIIIAO_02910 2.32e-160 - - - S - - - YjbR
HKFIIIAO_02911 3.05e-281 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HKFIIIAO_02912 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKFIIIAO_02913 7.12e-256 glmS2 - - M - - - SIS domain
HKFIIIAO_02914 3.58e-36 - - - S - - - Belongs to the LOG family
HKFIIIAO_02915 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HKFIIIAO_02916 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKFIIIAO_02917 4.58e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKFIIIAO_02918 4.75e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HKFIIIAO_02919 6.47e-208 - - - GM - - - NmrA-like family
HKFIIIAO_02920 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HKFIIIAO_02921 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HKFIIIAO_02922 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
HKFIIIAO_02923 1.7e-70 - - - - - - - -
HKFIIIAO_02924 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HKFIIIAO_02925 1.22e-81 - - - - - - - -
HKFIIIAO_02926 1.36e-112 - - - - - - - -
HKFIIIAO_02927 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKFIIIAO_02928 3.78e-73 - - - - - - - -
HKFIIIAO_02929 4.79e-21 - - - - - - - -
HKFIIIAO_02930 3.57e-150 - - - GM - - - NmrA-like family
HKFIIIAO_02931 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
HKFIIIAO_02932 9.43e-203 - - - EG - - - EamA-like transporter family
HKFIIIAO_02933 2.66e-155 - - - S - - - membrane
HKFIIIAO_02934 1.47e-144 - - - S - - - VIT family
HKFIIIAO_02935 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HKFIIIAO_02936 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HKFIIIAO_02937 8.01e-97 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HKFIIIAO_02938 4.26e-54 - - - - - - - -
HKFIIIAO_02939 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
HKFIIIAO_02940 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HKFIIIAO_02941 7.21e-35 - - - - - - - -
HKFIIIAO_02942 2.55e-65 - - - - - - - -
HKFIIIAO_02943 5.07e-84 - - - S - - - Protein of unknown function (DUF1398)
HKFIIIAO_02944 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HKFIIIAO_02945 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HKFIIIAO_02946 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
HKFIIIAO_02947 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HKFIIIAO_02948 4.66e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HKFIIIAO_02949 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HKFIIIAO_02950 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HKFIIIAO_02951 8.84e-182 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HKFIIIAO_02953 1.12e-208 yvgN - - C - - - Aldo keto reductase
HKFIIIAO_02954 2.57e-171 - - - S - - - Putative threonine/serine exporter
HKFIIIAO_02955 1.7e-101 - - - S - - - Threonine/Serine exporter, ThrE
HKFIIIAO_02956 1.5e-56 - - - S - - - Protein of unknown function (DUF1093)
HKFIIIAO_02957 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKFIIIAO_02958 5.94e-118 ymdB - - S - - - Macro domain protein
HKFIIIAO_02959 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HKFIIIAO_02960 1.58e-66 - - - - - - - -
HKFIIIAO_02961 1.39e-211 - - - S - - - Protein of unknown function (DUF1002)
HKFIIIAO_02962 0.0 - - - - - - - -
HKFIIIAO_02963 6.48e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
HKFIIIAO_02964 2e-41 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02965 9.84e-26 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02966 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HKFIIIAO_02967 5.33e-114 - - - K - - - Winged helix DNA-binding domain
HKFIIIAO_02968 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_02969 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HKFIIIAO_02970 4.45e-38 - - - - - - - -
HKFIIIAO_02971 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HKFIIIAO_02972 2.75e-96 - - - M - - - PFAM NLP P60 protein
HKFIIIAO_02973 6.18e-71 - - - - - - - -
HKFIIIAO_02974 5.77e-81 - - - - - - - -
HKFIIIAO_02976 9.39e-84 - - - - - - - -
HKFIIIAO_02978 2.42e-130 - - - K - - - transcriptional regulator
HKFIIIAO_02979 7.46e-35 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HKFIIIAO_02980 2.07e-154 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HKFIIIAO_02981 3.42e-174 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKFIIIAO_02982 1.5e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HKFIIIAO_02983 1.98e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HKFIIIAO_02984 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HKFIIIAO_02985 1.57e-181 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_02986 2.34e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HKFIIIAO_02987 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
HKFIIIAO_02988 1.01e-26 - - - - - - - -
HKFIIIAO_02989 1.74e-125 dpsB - - P - - - Belongs to the Dps family
HKFIIIAO_02990 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HKFIIIAO_02991 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HKFIIIAO_02992 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HKFIIIAO_02993 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKFIIIAO_02994 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HKFIIIAO_02995 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HKFIIIAO_02996 1.83e-235 - - - S - - - Cell surface protein
HKFIIIAO_02997 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02998 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HKFIIIAO_02999 7.83e-60 - - - - - - - -
HKFIIIAO_03000 8.19e-134 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HKFIIIAO_03001 1.03e-65 - - - - - - - -
HKFIIIAO_03002 4.67e-316 - - - S - - - Putative metallopeptidase domain
HKFIIIAO_03003 3.31e-282 - - - S - - - associated with various cellular activities
HKFIIIAO_03004 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKFIIIAO_03005 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HKFIIIAO_03006 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKFIIIAO_03007 4.67e-250 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HKFIIIAO_03008 4.18e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_03009 5.67e-212 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HKFIIIAO_03010 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKFIIIAO_03011 2.81e-90 - - - S - - - Domain of unknown function (DUF3284)
HKFIIIAO_03012 8.86e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_03013 1.13e-228 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HKFIIIAO_03014 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKFIIIAO_03015 5.02e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HKFIIIAO_03016 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKFIIIAO_03017 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HKFIIIAO_03018 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
HKFIIIAO_03019 6.22e-140 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HKFIIIAO_03020 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HKFIIIAO_03021 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKFIIIAO_03022 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HKFIIIAO_03023 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HKFIIIAO_03024 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKFIIIAO_03025 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKFIIIAO_03026 1.64e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HKFIIIAO_03027 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKFIIIAO_03028 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HKFIIIAO_03029 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HKFIIIAO_03030 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKFIIIAO_03031 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HKFIIIAO_03032 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
HKFIIIAO_03033 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HKFIIIAO_03034 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKFIIIAO_03035 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKFIIIAO_03036 1.12e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKFIIIAO_03037 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
HKFIIIAO_03038 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_03039 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKFIIIAO_03040 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKFIIIAO_03041 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HKFIIIAO_03042 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
HKFIIIAO_03043 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
HKFIIIAO_03044 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
HKFIIIAO_03045 4.93e-82 - - - - - - - -
HKFIIIAO_03046 2.63e-200 estA - - S - - - Putative esterase
HKFIIIAO_03047 5.44e-174 - - - K - - - UTRA domain
HKFIIIAO_03048 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKFIIIAO_03049 5.07e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKFIIIAO_03050 2.4e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HKFIIIAO_03051 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HKFIIIAO_03052 7.39e-98 - - - L - - - Transposase DDE domain
HKFIIIAO_03053 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03054 2.13e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKFIIIAO_03055 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HKFIIIAO_03056 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HKFIIIAO_03057 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
HKFIIIAO_03058 1.06e-16 - - - - - - - -
HKFIIIAO_03059 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HKFIIIAO_03060 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HKFIIIAO_03061 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HKFIIIAO_03062 7.42e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HKFIIIAO_03063 1.54e-162 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKFIIIAO_03064 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03065 1.76e-40 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKFIIIAO_03066 9.62e-19 - - - - - - - -
HKFIIIAO_03067 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HKFIIIAO_03068 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HKFIIIAO_03070 1.89e-254 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKFIIIAO_03071 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_03072 5.03e-95 - - - K - - - Transcriptional regulator
HKFIIIAO_03073 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKFIIIAO_03074 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HKFIIIAO_03075 5.88e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HKFIIIAO_03076 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HKFIIIAO_03077 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HKFIIIAO_03078 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HKFIIIAO_03079 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HKFIIIAO_03080 7.26e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HKFIIIAO_03081 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKFIIIAO_03082 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKFIIIAO_03083 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HKFIIIAO_03084 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HKFIIIAO_03085 2.51e-103 - - - T - - - Universal stress protein family
HKFIIIAO_03086 7.43e-130 padR - - K - - - Virulence activator alpha C-term
HKFIIIAO_03087 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HKFIIIAO_03088 6.11e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HKFIIIAO_03089 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
HKFIIIAO_03090 4.69e-202 degV1 - - S - - - DegV family
HKFIIIAO_03091 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HKFIIIAO_03092 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HKFIIIAO_03094 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKFIIIAO_03095 0.0 - - - - - - - -
HKFIIIAO_03097 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
HKFIIIAO_03098 1.31e-143 - - - S - - - Cell surface protein
HKFIIIAO_03099 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKFIIIAO_03100 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKFIIIAO_03101 2.26e-171 jag - - S ko:K06346 - ko00000 R3H domain protein
HKFIIIAO_03102 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HKFIIIAO_03103 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKFIIIAO_03104 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKFIIIAO_03105 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKFIIIAO_03106 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HKFIIIAO_03107 1.17e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKFIIIAO_03108 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
HKFIIIAO_03109 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HKFIIIAO_03110 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HKFIIIAO_03111 4.55e-75 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03112 3.59e-26 - - - - - - - -
HKFIIIAO_03113 1.45e-235 - - - L - - - Psort location Cytoplasmic, score
HKFIIIAO_03114 2.09e-41 - - - - - - - -
HKFIIIAO_03115 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03116 2.49e-247 - - - L - - - MobA MobL family protein
HKFIIIAO_03117 7.81e-131 traA - - L - - - MobA MobL family protein
HKFIIIAO_03118 1.69e-37 - - - - - - - -
HKFIIIAO_03119 1.03e-55 - - - - - - - -
HKFIIIAO_03120 6.76e-14 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03121 4.31e-72 - - - L - - - Transposase DDE domain
HKFIIIAO_03122 6.98e-211 - - - P - - - CorA-like Mg2+ transporter protein
HKFIIIAO_03123 1.79e-63 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03124 6.99e-109 - - - - - - - -
HKFIIIAO_03125 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HKFIIIAO_03126 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKFIIIAO_03128 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03130 4.62e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03131 1.71e-241 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03132 9.17e-126 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HKFIIIAO_03133 1.14e-143 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HKFIIIAO_03134 5.99e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HKFIIIAO_03135 7.09e-149 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
HKFIIIAO_03136 4.73e-53 - - - M - - - LysM domain protein
HKFIIIAO_03137 5.83e-182 - - - L - - - COG3547 Transposase and inactivated derivatives
HKFIIIAO_03138 0.0 eriC - - P ko:K03281 - ko00000 chloride
HKFIIIAO_03139 7.81e-247 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKFIIIAO_03140 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_03141 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03142 1.4e-213 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03143 2.61e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKFIIIAO_03144 1.06e-138 - - - L - - - Resolvase, N terminal domain
HKFIIIAO_03145 6.35e-147 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_03146 3.29e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HKFIIIAO_03147 5.59e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
HKFIIIAO_03148 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKFIIIAO_03149 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
HKFIIIAO_03150 1.98e-06 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
HKFIIIAO_03151 4.28e-81 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFIIIAO_03152 4.25e-198 - - - L ko:K07482 - ko00000 Integrase core domain
HKFIIIAO_03153 4.79e-123 tnpR1 - - L - - - Resolvase, N terminal domain
HKFIIIAO_03154 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03155 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_03156 5.49e-217 - - - L ko:K07482 - ko00000 Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03157 2.4e-160 tnp1216 - - L ko:K07498 - ko00000 DDE domain
HKFIIIAO_03158 1.56e-120 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKFIIIAO_03159 1.23e-151 - - - K - - - Transcriptional regulator
HKFIIIAO_03160 4.83e-252 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-type multidrug transport system, permease component
HKFIIIAO_03161 6.09e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKFIIIAO_03162 2.6e-48 - - - L - - - Transposase DDE domain
HKFIIIAO_03163 2.12e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKFIIIAO_03164 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HKFIIIAO_03165 3.32e-215 - - - L - - - Replication protein
HKFIIIAO_03167 2.47e-174 mob - - D - - - Plasmid recombination enzyme
HKFIIIAO_03168 3.08e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HKFIIIAO_03169 2.84e-193 tra981A - - L ko:K07497 - ko00000 Integrase core domain
HKFIIIAO_03170 2.65e-89 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HKFIIIAO_03171 4.36e-148 - - - EGP - - - Transmembrane secretion effector
HKFIIIAO_03172 3.07e-284 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_03173 9.33e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03174 2.48e-99 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
HKFIIIAO_03175 6.06e-76 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKFIIIAO_03176 1.87e-137 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_03177 0.0 - - - EGP - - - Major Facilitator
HKFIIIAO_03178 1.08e-111 - - - K - - - Domain of unknown function (DUF1836)
HKFIIIAO_03179 3.39e-192 degV - - S - - - Uncharacterised protein, DegV family COG1307
HKFIIIAO_03181 3.35e-49 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HKFIIIAO_03182 5.49e-316 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKFIIIAO_03183 2.23e-74 usp2 - - T - - - Belongs to the universal stress protein A family
HKFIIIAO_03184 6.9e-124 - - - L - - - Resolvase, N terminal domain
HKFIIIAO_03185 7.98e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKFIIIAO_03186 0.0 ybeC - - E - - - amino acid
HKFIIIAO_03187 7.04e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03188 1.36e-132 tnpR - - L - - - Resolvase, N terminal domain
HKFIIIAO_03190 0.0 - - - L - - - helicase activity
HKFIIIAO_03191 8.33e-279 - - - K - - - DNA binding
HKFIIIAO_03192 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HKFIIIAO_03193 0.0 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HKFIIIAO_03194 1.68e-130 is18 - - L - - - Integrase core domain
HKFIIIAO_03195 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HKFIIIAO_03196 1.05e-239 - - - L - - - Psort location Cytoplasmic, score
HKFIIIAO_03197 7.81e-46 - - - - - - - -
HKFIIIAO_03198 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03199 1.89e-94 - - - - - - - -
HKFIIIAO_03201 2.62e-294 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
HKFIIIAO_03202 3.88e-87 - - - - - - - -
HKFIIIAO_03203 2.77e-58 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HKFIIIAO_03204 2.17e-76 - - - - - - - -
HKFIIIAO_03205 1.59e-208 - - - M - - - CHAP domain
HKFIIIAO_03206 1.01e-298 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
HKFIIIAO_03207 0.0 traE - - U - - - Psort location Cytoplasmic, score
HKFIIIAO_03208 4.48e-152 - - - - - - - -
HKFIIIAO_03209 8.94e-70 - - - - - - - -
HKFIIIAO_03210 4.45e-66 - - - S - - - Cag pathogenicity island, type IV secretory system
HKFIIIAO_03211 5.9e-104 - - - - - - - -
HKFIIIAO_03213 0.0 traA - - L - - - MobA MobL family protein
HKFIIIAO_03214 1.63e-35 - - - - - - - -
HKFIIIAO_03215 1.21e-54 - - - - - - - -
HKFIIIAO_03216 4.7e-57 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HKFIIIAO_03217 8.19e-49 - - - L - - - Transposase DDE domain
HKFIIIAO_03218 3.82e-48 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03219 2.09e-40 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03220 1.78e-47 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKFIIIAO_03221 9.92e-122 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03223 6.46e-100 repA - - S - - - Replication initiator protein A
HKFIIIAO_03224 4.3e-36 - - - - - - - -
HKFIIIAO_03225 2.22e-162 - - - S - - - Fic/DOC family
HKFIIIAO_03226 6.12e-167 - - - L - - - Helix-turn-helix domain
HKFIIIAO_03227 7e-208 - - - L ko:K07497 - ko00000 hmm pf00665
HKFIIIAO_03228 2.13e-53 - - - - - - - -
HKFIIIAO_03229 1.39e-36 - - - - - - - -
HKFIIIAO_03230 0.0 traA - - L - - - MobA MobL family protein
HKFIIIAO_03231 1.73e-06 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03232 1.94e-158 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03233 1.93e-223 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03234 4.53e-45 - - - - - - - -
HKFIIIAO_03235 6.5e-10 - - - L - - - Psort location Cytoplasmic, score
HKFIIIAO_03236 1.54e-42 - - - L - - - Psort location Cytoplasmic, score
HKFIIIAO_03237 8.34e-51 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HKFIIIAO_03238 8.44e-201 is18 - - L - - - Integrase core domain
HKFIIIAO_03239 2.59e-34 - - - - - - - -
HKFIIIAO_03242 2.02e-126 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03244 6.86e-16 - - - - - - - -
HKFIIIAO_03245 9.76e-10 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_03247 1.78e-165 epsB - - M - - - biosynthesis protein
HKFIIIAO_03248 2.37e-163 ywqD - - D - - - Capsular exopolysaccharide family
HKFIIIAO_03249 2.28e-173 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HKFIIIAO_03250 7.13e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HKFIIIAO_03251 2.83e-199 is18 - - L - - - Integrase core domain
HKFIIIAO_03252 7.48e-134 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HKFIIIAO_03253 1.36e-83 tuaA - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKFIIIAO_03254 6.08e-71 - - GT2 M ko:K12997,ko:K16698 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
HKFIIIAO_03255 9.88e-133 - - - M - - - Stealth protein CR2, conserved region 2
HKFIIIAO_03256 6.12e-85 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKFIIIAO_03257 1.95e-249 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03259 1.48e-246 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HKFIIIAO_03260 8.63e-60 cps2G - - M - - - Stealth protein CR2, conserved region 2
HKFIIIAO_03261 1.53e-49 murJ - - S ko:K03980 - ko00000,ko01011,ko02000 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKFIIIAO_03263 7.13e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
HKFIIIAO_03264 2.83e-199 is18 - - L - - - Integrase core domain
HKFIIIAO_03265 3.47e-184 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03266 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
HKFIIIAO_03268 1.95e-45 ydaT - - - - - - -
HKFIIIAO_03269 2.08e-35 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKFIIIAO_03270 3.1e-93 - - - L - - - Integrase core domain
HKFIIIAO_03271 8.83e-06 - - - - - - - -
HKFIIIAO_03272 1.45e-54 - - - D - - - AAA domain
HKFIIIAO_03273 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03275 7.88e-80 - - - EGP - - - Major Facilitator
HKFIIIAO_03276 2.87e-76 - - - S - - - Family of unknown function (DUF5388)
HKFIIIAO_03277 2.13e-188 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03278 4.58e-114 - - - L - - - Transposase
HKFIIIAO_03279 1.99e-49 - - - L - - - Transposase
HKFIIIAO_03280 5.81e-88 - - - L - - - Transposase
HKFIIIAO_03281 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03282 2.95e-142 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HKFIIIAO_03283 7.69e-224 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HKFIIIAO_03284 1.72e-110 - - - K - - - Bacterial regulatory proteins, tetR family
HKFIIIAO_03285 2.76e-49 - - - - - - - -
HKFIIIAO_03286 5.81e-88 - - - L - - - Transposase
HKFIIIAO_03287 5.8e-46 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03288 2.82e-193 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03289 3.57e-47 - - - - - - - -
HKFIIIAO_03290 3.04e-23 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKFIIIAO_03291 5.61e-90 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
HKFIIIAO_03292 4.74e-133 tnpR - - L - - - Resolvase, N terminal domain
HKFIIIAO_03293 1.46e-21 - - - S - - - FRG
HKFIIIAO_03294 3.77e-278 - - - EGP - - - Major Facilitator
HKFIIIAO_03295 1.62e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKFIIIAO_03296 1.13e-219 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
HKFIIIAO_03297 3.43e-272 B4168_4126 - - L ko:K07493 - ko00000 Transposase
HKFIIIAO_03298 2.43e-214 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03299 1.18e-192 degV - - S - - - Uncharacterised protein, DegV family COG1307
HKFIIIAO_03300 1.32e-112 - - - K - - - Domain of unknown function (DUF1836)
HKFIIIAO_03301 1.29e-280 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HKFIIIAO_03302 4.05e-242 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKFIIIAO_03303 2.27e-107 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HKFIIIAO_03304 1.4e-133 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKFIIIAO_03305 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKFIIIAO_03306 0.0 - - - L - - - MobA MobL family protein
HKFIIIAO_03307 8.06e-36 - - - - - - - -
HKFIIIAO_03308 6.68e-57 - - - - - - - -
HKFIIIAO_03309 7.66e-42 - - - S - - - protein conserved in bacteria
HKFIIIAO_03310 4.01e-49 - - - L - - - Transposase
HKFIIIAO_03311 1.65e-109 - - - L - - - Transposase
HKFIIIAO_03312 1.2e-18 - - - - - - - -
HKFIIIAO_03313 2.29e-108 repA - - S - - - Replication initiator protein A
HKFIIIAO_03314 6.86e-124 mgtC3 - - S ko:K07507 - ko00000,ko02000 MgtC family
HKFIIIAO_03316 2.39e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKFIIIAO_03318 8.33e-102 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03319 3.46e-148 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03320 5.78e-72 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HKFIIIAO_03321 2.12e-315 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKFIIIAO_03322 1.93e-222 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HKFIIIAO_03323 6.98e-242 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKFIIIAO_03324 9.69e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKFIIIAO_03325 6.24e-225 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HKFIIIAO_03326 4.57e-303 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKFIIIAO_03327 2.92e-234 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HKFIIIAO_03328 4.02e-80 - - - S - - - Haem-degrading
HKFIIIAO_03329 5.63e-189 - - - C - - - Alcohol dehydrogenase GroES-like domain
HKFIIIAO_03330 6.21e-196 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HKFIIIAO_03331 2.12e-145 - - - K - - - Helix-turn-helix domain, rpiR family
HKFIIIAO_03332 6.78e-16 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKFIIIAO_03333 9.24e-76 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKFIIIAO_03334 1.47e-55 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKFIIIAO_03335 6.25e-123 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HKFIIIAO_03336 4.58e-140 - - - L - - - Integrase
HKFIIIAO_03337 1.58e-46 - - - Q - - - ubiE/COQ5 methyltransferase family
HKFIIIAO_03338 3.82e-48 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03339 8.19e-49 - - - L - - - Transposase DDE domain
HKFIIIAO_03341 2.4e-57 repB - - L - - - Initiator Replication protein
HKFIIIAO_03343 1.21e-35 - - - - - - - -
HKFIIIAO_03344 4.84e-38 - - - S - - - Psort location CytoplasmicMembrane, score
HKFIIIAO_03345 2.14e-33 mpr - - E - - - Trypsin-like serine protease
HKFIIIAO_03346 1.09e-56 - - - L - - - 4.5 Transposon and IS
HKFIIIAO_03347 9.04e-78 yafQ - - S ko:K19157 - ko00000,ko01000,ko02048 endonuclease activity
HKFIIIAO_03348 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HKFIIIAO_03349 5.76e-134 - - - L - - - Integrase
HKFIIIAO_03350 1.71e-38 - - - - - - - -
HKFIIIAO_03352 2.69e-35 - - - - - - - -
HKFIIIAO_03354 2.03e-182 - - - - - - - -
HKFIIIAO_03357 3.56e-152 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKFIIIAO_03359 8.33e-102 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03360 3.46e-148 - - - L - - - PFAM Integrase catalytic region
HKFIIIAO_03361 8.58e-71 - - - K - - - Helix-turn-helix XRE-family like proteins
HKFIIIAO_03362 7.1e-81 - - - S - - - Protein of unknown function (DUF2992)
HKFIIIAO_03363 3.15e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HKFIIIAO_03364 8.63e-68 - - - S - - - Bacterial mobilisation protein (MobC)
HKFIIIAO_03365 3.03e-49 - - - K - - - sequence-specific DNA binding
HKFIIIAO_03366 2.08e-60 - - - S - - - Phage derived protein Gp49-like (DUF891)
HKFIIIAO_03367 7.6e-139 - - - L - - - Integrase
HKFIIIAO_03368 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HKFIIIAO_03369 9.04e-78 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HKFIIIAO_03371 1.39e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HKFIIIAO_03372 5.12e-112 - - - - - - - -
HKFIIIAO_03373 1.24e-39 - - - - - - - -
HKFIIIAO_03374 1.45e-103 - - - L - - - Phage integrase family
HKFIIIAO_03375 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKFIIIAO_03376 4.59e-58 - - - - - - - -
HKFIIIAO_03377 4.79e-39 repA - - S - - - Replication initiator protein A
HKFIIIAO_03379 4.16e-193 - - - L - - - Initiator Replication protein
HKFIIIAO_03380 7.92e-82 - - - S - - - Protein of unknown function, DUF536
HKFIIIAO_03381 8.48e-147 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 restriction endonuclease
HKFIIIAO_03382 0.0 - - - L - - - Type III restriction enzyme res subunit
HKFIIIAO_03383 2e-75 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKFIIIAO_03384 1.02e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
HKFIIIAO_03385 3.92e-141 - - - L - - - Integrase
HKFIIIAO_03386 5.77e-149 - - - - - - - -
HKFIIIAO_03387 4.28e-243 - - - S - - - MobA/MobL family
HKFIIIAO_03388 0.000307 - - - S - - - Protein of unknown function (DUF3847)
HKFIIIAO_03389 3.11e-39 repB - - L - - - Initiator Replication protein
HKFIIIAO_03391 9.24e-140 - - - L - - - Integrase
HKFIIIAO_03392 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
HKFIIIAO_03393 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKFIIIAO_03394 5.41e-06 - - - L ko:K07483 - ko00000 Transposase
HKFIIIAO_03395 4.55e-46 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HKFIIIAO_03396 3.54e-147 - - - EGP - - - Transmembrane secretion effector
HKFIIIAO_03399 5.55e-86 - - - L - - - Transposase
HKFIIIAO_03400 2.96e-38 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03401 4.51e-30 - - - - - - - -
HKFIIIAO_03402 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HKFIIIAO_03403 3.13e-99 - - - L - - - Transposase DDE domain
HKFIIIAO_03405 2.29e-225 - - - L - - - Initiator Replication protein
HKFIIIAO_03406 6.66e-115 - - - - - - - -
HKFIIIAO_03407 1.39e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HKFIIIAO_03409 3.29e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
HKFIIIAO_03410 8.83e-57 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HKFIIIAO_03411 5.93e-41 - - - L - - - Integrase
HKFIIIAO_03412 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKFIIIAO_03413 4.69e-86 - - - L - - - Integrase
HKFIIIAO_03414 3.28e-33 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)