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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PIICGBBI_00001	3.18e-35	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIICGBBI_00002	4.93e-229	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIICGBBI_00003	7.59e-269	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
PIICGBBI_00004	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PIICGBBI_00005	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIICGBBI_00006	4.62e-181	-	-	-	-	-	-	-	-
PIICGBBI_00007	8.64e-176	-	-	-	-	-	-	-	-
PIICGBBI_00008	1.84e-170	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIICGBBI_00009	8.51e-143	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIICGBBI_00010	1.96e-132	-	-	-	G	-	-	-	Aldose 1-epimerase
PIICGBBI_00011	1.34e-259	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIICGBBI_00012	2.73e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIICGBBI_00013	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
PIICGBBI_00014	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
PIICGBBI_00015	6.28e-310	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIICGBBI_00016	1.02e-74	-	-	-	-	-	-	-	-
PIICGBBI_00018	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PIICGBBI_00019	1.16e-162	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIICGBBI_00020	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIICGBBI_00021	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIICGBBI_00022	8.86e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIICGBBI_00023	5.46e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIICGBBI_00024	1.92e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIICGBBI_00025	1.9e-256	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_00026	1.87e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_00027	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PIICGBBI_00028	1.5e-96	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PIICGBBI_00029	6.92e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIICGBBI_00030	1.09e-148	-	-	-	-	-	-	-	-
PIICGBBI_00032	1.21e-146	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
PIICGBBI_00033	2.35e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIICGBBI_00034	2.69e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
PIICGBBI_00035	1.25e-142	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PIICGBBI_00036	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PIICGBBI_00037	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIICGBBI_00038	2.33e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PIICGBBI_00039	1.63e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIICGBBI_00040	4.9e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIICGBBI_00041	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PIICGBBI_00042	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PIICGBBI_00043	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIICGBBI_00044	1.4e-116	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_00045	5.1e-116	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_00046	1.48e-114	-	-	-	-	-	-	-	-
PIICGBBI_00047	0.0	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_00048	2.68e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIICGBBI_00049	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_00050	3.82e-167	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIICGBBI_00051	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_00052	4.58e-216	-	-	-	GK	-	-	-	ROK family
PIICGBBI_00053	4.88e-59	-	-	-	-	-	-	-	-
PIICGBBI_00054	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIICGBBI_00055	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PIICGBBI_00056	1.11e-96	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIICGBBI_00057	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIICGBBI_00058	6.32e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIICGBBI_00059	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIICGBBI_00060	7.87e-207	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
PIICGBBI_00061	8.61e-139	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIICGBBI_00062	1.21e-285	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PIICGBBI_00063	5.8e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIICGBBI_00064	1.04e-173	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PIICGBBI_00065	3.77e-220	-	-	-	K	-	-	-	Helix-turn-helix
PIICGBBI_00066	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PIICGBBI_00067	7.77e-199	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_00068	3.12e-191	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PIICGBBI_00069	1.03e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIICGBBI_00070	1.16e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIICGBBI_00071	7.88e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIICGBBI_00072	1.29e-172	XK27_07210	-	-	S	-	-	-	B3 4 domain
PIICGBBI_00073	2.07e-117	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
PIICGBBI_00074	2.89e-44	-	-	-	P	-	-	-	Belongs to the major facilitator superfamily
PIICGBBI_00075	5.49e-42	-	-	-	-	-	-	-	-
PIICGBBI_00076	3.18e-106	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIICGBBI_00077	6.74e-39	-	-	-	K	ko:K12410	-	ko00000,ko01000	NAD+ binding
PIICGBBI_00078	4.62e-13	-	-	-	P	-	-	-	Voltage gated chloride channel
PIICGBBI_00079	7.47e-126	-	-	-	-	-	-	-	-
PIICGBBI_00080	8.2e-68	-	-	-	-	-	-	-	-
PIICGBBI_00081	4.88e-59	-	-	-	-	-	-	-	-
PIICGBBI_00082	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIICGBBI_00083	0.0	-	-	-	E	-	-	-	amino acid
PIICGBBI_00084	9.8e-204	supH	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PIICGBBI_00085	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
PIICGBBI_00086	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PIICGBBI_00087	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIICGBBI_00088	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIICGBBI_00089	3.27e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIICGBBI_00090	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIICGBBI_00091	1.68e-164	-	-	-	S	-	-	-	(CBS) domain
PIICGBBI_00092	1.98e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PIICGBBI_00093	6.58e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIICGBBI_00094	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIICGBBI_00095	1.79e-46	yabO	-	-	J	-	-	-	S4 domain protein
PIICGBBI_00096	1.03e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PIICGBBI_00097	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
PIICGBBI_00098	5.11e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIICGBBI_00099	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIICGBBI_00100	6.77e-215	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIICGBBI_00101	3.5e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIICGBBI_00102	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PIICGBBI_00105	1.16e-107	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PIICGBBI_00106	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIICGBBI_00107	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIICGBBI_00108	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIICGBBI_00109	6.6e-159	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PIICGBBI_00110	2.09e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIICGBBI_00111	1.62e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIICGBBI_00112	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIICGBBI_00113	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PIICGBBI_00114	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIICGBBI_00115	1.91e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PIICGBBI_00116	3.57e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIICGBBI_00117	9.85e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIICGBBI_00118	3.83e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIICGBBI_00119	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIICGBBI_00120	7.15e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIICGBBI_00121	9.64e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIICGBBI_00122	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PIICGBBI_00123	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIICGBBI_00124	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIICGBBI_00125	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIICGBBI_00126	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIICGBBI_00127	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIICGBBI_00128	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIICGBBI_00129	2.5e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIICGBBI_00130	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIICGBBI_00131	5.3e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIICGBBI_00132	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PIICGBBI_00133	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIICGBBI_00134	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIICGBBI_00135	1.51e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIICGBBI_00136	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIICGBBI_00137	4.63e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PIICGBBI_00138	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIICGBBI_00139	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIICGBBI_00140	2.55e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIICGBBI_00141	1.57e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PIICGBBI_00142	4.16e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIICGBBI_00143	4.04e-206	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIICGBBI_00144	1.74e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIICGBBI_00145	4.17e-192	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIICGBBI_00146	1.6e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIICGBBI_00147	8.28e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PIICGBBI_00148	7.71e-255	-	-	-	L	-	-	-	Phage integrase family
PIICGBBI_00149	4.24e-37	-	-	-	-	-	-	-	-
PIICGBBI_00150	1.31e-270	-	-	-	EP	-	-	-	Plasmid replication protein
PIICGBBI_00151	1.77e-61	-	-	-	-	-	-	-	-
PIICGBBI_00152	2.52e-264	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PIICGBBI_00153	1.48e-69	-	-	-	-	-	-	-	-
PIICGBBI_00155	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
PIICGBBI_00156	1.53e-85	-	-	-	S	-	-	-	YjcQ protein
PIICGBBI_00158	5.27e-16	-	-	-	-	-	-	-	-
PIICGBBI_00159	8.56e-140	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PIICGBBI_00160	4.67e-154	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PIICGBBI_00161	8.09e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PIICGBBI_00162	1.63e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PIICGBBI_00163	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PIICGBBI_00164	1.14e-27	-	-	-	-	-	-	-	-
PIICGBBI_00165	8.64e-153	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIICGBBI_00166	9.84e-236	-	-	-	S	-	-	-	AAA domain
PIICGBBI_00167	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIICGBBI_00168	9.95e-70	-	-	-	-	-	-	-	-
PIICGBBI_00169	1.82e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PIICGBBI_00170	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIICGBBI_00171	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIICGBBI_00172	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIICGBBI_00173	6.01e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIICGBBI_00174	8.7e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIICGBBI_00175	2.91e-121	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
PIICGBBI_00176	2.41e-45	-	-	-	-	-	-	-	-
PIICGBBI_00177	6.48e-148	-	-	-	-	-	-	-	-
PIICGBBI_00178	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PIICGBBI_00179	1.22e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIICGBBI_00180	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIICGBBI_00181	1.72e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIICGBBI_00182	3.66e-132	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PIICGBBI_00183	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIICGBBI_00184	1.5e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIICGBBI_00185	2.83e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PIICGBBI_00186	1.8e-223	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PIICGBBI_00187	4.47e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PIICGBBI_00188	4.47e-186	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIICGBBI_00189	5.67e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIICGBBI_00190	1.74e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PIICGBBI_00191	7.3e-268	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PIICGBBI_00192	1.61e-39	-	-	-	-	-	-	-	-
PIICGBBI_00193	2.15e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIICGBBI_00194	9.31e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIICGBBI_00195	3.83e-167	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
PIICGBBI_00196	1.25e-147	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PIICGBBI_00197	4.9e-33	-	-	-	-	-	-	-	-
PIICGBBI_00198	9.21e-120	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIICGBBI_00199	2.2e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIICGBBI_00200	4.56e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIICGBBI_00201	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PIICGBBI_00202	1.69e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIICGBBI_00203	1.85e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PIICGBBI_00204	5.91e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIICGBBI_00205	2.65e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PIICGBBI_00206	9.46e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIICGBBI_00207	1.06e-181	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PIICGBBI_00208	1.59e-112	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PIICGBBI_00209	8.02e-172	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PIICGBBI_00210	4.26e-138	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PIICGBBI_00211	5.62e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIICGBBI_00212	9.05e-170	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIICGBBI_00213	7.2e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIICGBBI_00214	4.46e-165	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
PIICGBBI_00215	1.38e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PIICGBBI_00216	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PIICGBBI_00217	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PIICGBBI_00218	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PIICGBBI_00219	1.24e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIICGBBI_00220	6.41e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PIICGBBI_00221	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PIICGBBI_00222	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_00223	4.92e-107	-	-	-	-	-	-	-	-
PIICGBBI_00224	1.33e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIICGBBI_00225	2.29e-175	-	-	-	S	-	-	-	membrane
PIICGBBI_00226	2.22e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIICGBBI_00227	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIICGBBI_00228	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIICGBBI_00229	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIICGBBI_00230	2.35e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIICGBBI_00231	1.61e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIICGBBI_00232	2.41e-83	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIICGBBI_00233	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIICGBBI_00234	1.32e-255	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIICGBBI_00235	9.43e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PIICGBBI_00236	8.26e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIICGBBI_00237	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIICGBBI_00238	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PIICGBBI_00239	3.27e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIICGBBI_00240	8.28e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PIICGBBI_00241	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIICGBBI_00242	1.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PIICGBBI_00243	1.46e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIICGBBI_00244	2.57e-91	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PIICGBBI_00245	1.33e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PIICGBBI_00246	1.42e-143	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIICGBBI_00247	3.18e-165	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PIICGBBI_00248	2.09e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIICGBBI_00249	1.37e-74	-	-	-	-	-	-	-	-
PIICGBBI_00250	4.1e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIICGBBI_00251	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PIICGBBI_00252	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PIICGBBI_00253	2.5e-74	-	-	-	-	-	-	-	-
PIICGBBI_00254	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PIICGBBI_00255	6.99e-134	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PIICGBBI_00256	5.46e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIICGBBI_00257	3.19e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PIICGBBI_00258	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PIICGBBI_00259	4.65e-193	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PIICGBBI_00264	1.98e-96	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIICGBBI_00265	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIICGBBI_00266	3.83e-61	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIICGBBI_00278	2.24e-284	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
PIICGBBI_00279	1.5e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PIICGBBI_00280	5.18e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIICGBBI_00281	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIICGBBI_00282	5.29e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIICGBBI_00283	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIICGBBI_00284	1.99e-99	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIICGBBI_00285	1.36e-241	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIICGBBI_00286	1.67e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PIICGBBI_00287	1.96e-224	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PIICGBBI_00288	2.86e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
PIICGBBI_00289	7.93e-206	-	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_00290	3.62e-89	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PIICGBBI_00291	2.27e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PIICGBBI_00292	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PIICGBBI_00293	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIICGBBI_00294	6.58e-113	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIICGBBI_00295	4.27e-139	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIICGBBI_00296	1.63e-175	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PIICGBBI_00297	8.15e-94	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
PIICGBBI_00298	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PIICGBBI_00299	0.0	-	-	-	S	-	-	-	TerB-C domain
PIICGBBI_00300	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
PIICGBBI_00301	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PIICGBBI_00302	1.21e-44	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PIICGBBI_00303	4.47e-81	-	-	-	-	-	-	-	-
PIICGBBI_00304	1.14e-294	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PIICGBBI_00305	8.42e-187	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PIICGBBI_00307	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
PIICGBBI_00308	8.95e-47	-	-	-	S	-	-	-	AAA ATPase domain
PIICGBBI_00309	0.0	-	-	-	S	-	-	-	AAA ATPase domain
PIICGBBI_00310	1.41e-208	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
PIICGBBI_00311	8.37e-161	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PIICGBBI_00313	8.66e-76	-	-	-	-	-	-	-	-
PIICGBBI_00314	2.66e-270	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PIICGBBI_00316	3.69e-244	-	-	-	EP	-	-	-	Plasmid replication protein
PIICGBBI_00317	6.89e-06	-	-	-	-	-	-	-	-
PIICGBBI_00318	2.79e-296	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIICGBBI_00319	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIICGBBI_00320	3.99e-45	-	-	-	-	-	-	-	-
PIICGBBI_00321	3.99e-88	-	-	-	-	-	-	-	-
PIICGBBI_00322	4.72e-80	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
PIICGBBI_00323	3.57e-113	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
PIICGBBI_00324	2.6e-19	-	-	-	-	-	-	-	-
PIICGBBI_00325	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_00326	4.35e-207	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PIICGBBI_00327	2.62e-111	-	-	-	M	-	-	-	LysM domain protein
PIICGBBI_00328	3.81e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
PIICGBBI_00329	1e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PIICGBBI_00330	2.57e-139	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
PIICGBBI_00331	9.82e-156	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PIICGBBI_00332	9.11e-69	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PIICGBBI_00333	3.74e-39	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PIICGBBI_00334	7.11e-236	lacI	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PIICGBBI_00335	0.0	-	-	-	G	ko:K02027,ko:K10120	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIICGBBI_00336	1.78e-209	-	-	-	P	ko:K10121	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PIICGBBI_00337	2.93e-199	msmG	-	-	G	ko:K02026,ko:K10122	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_00338	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
PIICGBBI_00339	8.89e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_00340	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PIICGBBI_00341	3.18e-92	-	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_00343	6.76e-227	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PIICGBBI_00344	0.0	slpX	-	-	S	-	-	-	SLAP domain
PIICGBBI_00347	5.81e-272	-	-	-	-	-	-	-	-
PIICGBBI_00348	1.33e-160	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PIICGBBI_00349	2.13e-92	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
PIICGBBI_00350	1.39e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PIICGBBI_00351	1.85e-264	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIICGBBI_00352	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIICGBBI_00353	5.7e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIICGBBI_00354	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIICGBBI_00355	3.89e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PIICGBBI_00356	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIICGBBI_00357	8.44e-177	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PIICGBBI_00358	6.32e-83	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PIICGBBI_00360	1.19e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PIICGBBI_00361	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PIICGBBI_00362	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIICGBBI_00363	7.29e-267	camS	-	-	S	-	-	-	sex pheromone
PIICGBBI_00364	4.46e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIICGBBI_00365	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIICGBBI_00366	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIICGBBI_00367	2.37e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PIICGBBI_00368	8.38e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PIICGBBI_00369	4.94e-75	-	-	-	-	-	-	-	-
PIICGBBI_00370	1.28e-310	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PIICGBBI_00371	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIICGBBI_00372	4.2e-30	-	-	-	-	-	-	-	-
PIICGBBI_00373	1.48e-82	-	-	-	-	-	-	-	-
PIICGBBI_00374	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PIICGBBI_00375	5.51e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
PIICGBBI_00376	1.05e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PIICGBBI_00377	4.33e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PIICGBBI_00378	1.48e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PIICGBBI_00379	3.15e-62	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
PIICGBBI_00380	2.43e-76	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
PIICGBBI_00381	2.98e-246	-	-	-	L	ko:K06400	-	ko00000	Recombinase
PIICGBBI_00382	3.28e-122	-	-	-	L	-	-	-	Resolvase, N terminal domain
PIICGBBI_00383	9.05e-231	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
PIICGBBI_00384	3.49e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIICGBBI_00389	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_00390	1.88e-174	-	-	-	S	-	-	-	CAAX protease self-immunity
PIICGBBI_00391	1.25e-118	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIICGBBI_00392	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PIICGBBI_00393	3.79e-101	-	-	-	K	-	-	-	acetyltransferase
PIICGBBI_00394	4.73e-206	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PIICGBBI_00395	5.13e-141	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_00396	3.37e-128	XK27_08575	-	-	V	ko:K06148	-	ko00000,ko02000	cysteine transport
PIICGBBI_00397	9.12e-24	XK27_08575	-	-	V	ko:K06148	-	ko00000,ko02000	cysteine transport
PIICGBBI_00398	5.36e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PIICGBBI_00399	1.39e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIICGBBI_00400	3.27e-110	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PIICGBBI_00401	2.03e-67	-	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
PIICGBBI_00402	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_00403	3.81e-274	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
PIICGBBI_00404	1.11e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PIICGBBI_00405	7.56e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PIICGBBI_00406	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PIICGBBI_00407	1.4e-188	-	-	-	-	-	-	-	-
PIICGBBI_00408	2.22e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_00409	6.57e-102	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PIICGBBI_00410	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_00411	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
PIICGBBI_00412	8.88e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PIICGBBI_00413	1.92e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
PIICGBBI_00414	2.39e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_00415	4.3e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_00416	1.43e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_00417	8.28e-143	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_00418	3.66e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PIICGBBI_00419	2.75e-95	-	-	-	-	-	-	-	-
PIICGBBI_00420	5.02e-313	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIICGBBI_00421	5.34e-211	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PIICGBBI_00422	3.74e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIICGBBI_00423	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIICGBBI_00424	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIICGBBI_00425	3.51e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PIICGBBI_00426	2.7e-173	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PIICGBBI_00427	1.81e-28	-	-	-	-	-	-	-	-
PIICGBBI_00428	5.7e-146	-	-	-	-	-	-	-	-
PIICGBBI_00429	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIICGBBI_00430	2.07e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PIICGBBI_00431	1.21e-93	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PIICGBBI_00432	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PIICGBBI_00433	1.82e-77	-	-	-	S	-	-	-	Enterocin A Immunity
PIICGBBI_00434	3.4e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PIICGBBI_00435	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PIICGBBI_00436	5.31e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
PIICGBBI_00437	7.37e-293	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PIICGBBI_00438	2.3e-186	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PIICGBBI_00439	6.92e-283	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIICGBBI_00440	1.35e-196	-	-	-	S	-	-	-	hydrolase
PIICGBBI_00441	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PIICGBBI_00442	1.29e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PIICGBBI_00443	1.07e-103	-	-	-	-	-	-	-	-
PIICGBBI_00444	5.61e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PIICGBBI_00445	1.51e-53	-	-	-	-	-	-	-	-
PIICGBBI_00446	9.09e-156	-	-	-	C	-	-	-	nitroreductase
PIICGBBI_00447	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PIICGBBI_00448	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIICGBBI_00449	3.27e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
PIICGBBI_00450	9.79e-168	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIICGBBI_00451	2.35e-269	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PIICGBBI_00452	5.88e-312	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_00455	2.81e-279	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIICGBBI_00456	4.67e-116	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
PIICGBBI_00457	8.53e-104	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PIICGBBI_00458	7.02e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PIICGBBI_00459	1.14e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PIICGBBI_00460	6.78e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PIICGBBI_00461	3.81e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PIICGBBI_00462	3.42e-278	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PIICGBBI_00463	3.82e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PIICGBBI_00464	2.95e-61	-	-	-	-	-	-	-	-
PIICGBBI_00465	2.13e-227	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PIICGBBI_00466	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIICGBBI_00467	4.13e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PIICGBBI_00468	7.42e-112	-	-	-	-	-	-	-	-
PIICGBBI_00469	1.02e-93	-	-	-	-	-	-	-	-
PIICGBBI_00470	1.24e-201	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PIICGBBI_00471	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIICGBBI_00472	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PIICGBBI_00473	9e-203	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PIICGBBI_00474	1.51e-269	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PIICGBBI_00475	9.05e-55	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PIICGBBI_00476	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIICGBBI_00477	1.08e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIICGBBI_00478	2.91e-175	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIICGBBI_00479	2.56e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PIICGBBI_00480	7.54e-149	yjbH	-	-	Q	-	-	-	Thioredoxin
PIICGBBI_00481	1.46e-145	-	-	-	S	-	-	-	CYTH
PIICGBBI_00482	1.15e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PIICGBBI_00483	6.41e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIICGBBI_00484	1.81e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIICGBBI_00485	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PIICGBBI_00486	8.93e-153	-	-	-	S	-	-	-	SNARE associated Golgi protein
PIICGBBI_00487	1.06e-257	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PIICGBBI_00488	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PIICGBBI_00489	8.1e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PIICGBBI_00490	8.9e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PIICGBBI_00491	1.75e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIICGBBI_00492	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PIICGBBI_00493	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PIICGBBI_00494	4.09e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PIICGBBI_00495	2.64e-305	ymfH	-	-	S	-	-	-	Peptidase M16
PIICGBBI_00496	8.02e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PIICGBBI_00497	1.43e-160	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PIICGBBI_00498	1.73e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIICGBBI_00499	6.24e-247	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIICGBBI_00500	2.13e-292	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PIICGBBI_00501	3.37e-271	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PIICGBBI_00502	2.05e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PIICGBBI_00503	8.33e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PIICGBBI_00504	7.21e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PIICGBBI_00505	1.75e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIICGBBI_00506	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIICGBBI_00507	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIICGBBI_00508	1.88e-21	-	-	-	-	-	-	-	-
PIICGBBI_00509	6.85e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIICGBBI_00510	4.36e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIICGBBI_00511	1.71e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PIICGBBI_00512	9.38e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIICGBBI_00513	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PIICGBBI_00514	6.25e-136	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PIICGBBI_00515	4.45e-126	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PIICGBBI_00516	5.82e-272	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PIICGBBI_00517	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PIICGBBI_00518	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PIICGBBI_00519	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIICGBBI_00520	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PIICGBBI_00521	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIICGBBI_00522	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIICGBBI_00523	3.8e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PIICGBBI_00524	6e-212	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PIICGBBI_00525	3.24e-250	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PIICGBBI_00526	1.17e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PIICGBBI_00527	2.16e-129	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIICGBBI_00528	0.0	ycaM	-	-	E	-	-	-	amino acid
PIICGBBI_00530	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PIICGBBI_00531	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIICGBBI_00532	9.96e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PIICGBBI_00533	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIICGBBI_00534	1.07e-125	-	-	-	-	-	-	-	-
PIICGBBI_00535	1.02e-202	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIICGBBI_00536	1.15e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIICGBBI_00537	3.84e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PIICGBBI_00538	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PIICGBBI_00539	5.26e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIICGBBI_00540	7.27e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PIICGBBI_00541	2.94e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIICGBBI_00542	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_00543	2.65e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_00544	9.5e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_00545	1.06e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIICGBBI_00546	3.38e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
PIICGBBI_00547	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIICGBBI_00548	4.85e-191	-	-	-	S	-	-	-	hydrolase
PIICGBBI_00549	5.9e-187	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIICGBBI_00550	7.3e-156	-	-	-	-	-	-	-	-
PIICGBBI_00551	2.73e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIICGBBI_00552	1.37e-269	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PIICGBBI_00553	2.7e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIICGBBI_00554	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_00555	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_00556	6.14e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PIICGBBI_00557	0.0	-	-	-	E	-	-	-	Amino acid permease
PIICGBBI_00558	1.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIICGBBI_00559	2.34e-119	-	-	-	S	-	-	-	VanZ like family
PIICGBBI_00560	1.97e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PIICGBBI_00561	1.38e-228	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PIICGBBI_00562	5.57e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PIICGBBI_00563	1.55e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
PIICGBBI_00564	9e-94	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
PIICGBBI_00565	1.33e-25	-	-	-	-	-	-	-	-
PIICGBBI_00566	2.61e-120	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
PIICGBBI_00567	4.19e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PIICGBBI_00568	2.24e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIICGBBI_00570	1.05e-170	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PIICGBBI_00571	3.52e-224	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PIICGBBI_00572	4.53e-41	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PIICGBBI_00573	1.86e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PIICGBBI_00574	1.68e-81	-	-	-	S	-	-	-	SdpI/YhfL protein family
PIICGBBI_00575	3.67e-91	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PIICGBBI_00576	3.31e-55	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PIICGBBI_00577	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PIICGBBI_00578	4.37e-81	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PIICGBBI_00579	1.53e-159	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PIICGBBI_00580	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIICGBBI_00581	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
PIICGBBI_00582	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PIICGBBI_00583	5.4e-316	-	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_00584	7.36e-251	ampC	-	-	V	-	-	-	Beta-lactamase
PIICGBBI_00587	2.17e-85	-	-	-	-	-	-	-	-
PIICGBBI_00588	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
PIICGBBI_00589	1.18e-47	-	-	-	-	-	-	-	-
PIICGBBI_00590	6.8e-46	-	-	-	-	-	-	-	-
PIICGBBI_00591	3.84e-90	-	-	-	-	-	-	-	-
PIICGBBI_00592	2.58e-49	-	-	-	-	-	-	-	-
PIICGBBI_00594	3.5e-75	-	-	-	K	-	-	-	Transcriptional
PIICGBBI_00595	4.33e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIICGBBI_00596	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PIICGBBI_00597	4.64e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PIICGBBI_00598	1.01e-235	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIICGBBI_00599	2.52e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIICGBBI_00600	4.93e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIICGBBI_00601	1.84e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIICGBBI_00602	4.13e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PIICGBBI_00603	4.36e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIICGBBI_00604	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIICGBBI_00605	6.82e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIICGBBI_00606	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIICGBBI_00607	1.22e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIICGBBI_00608	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIICGBBI_00609	7.03e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PIICGBBI_00610	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PIICGBBI_00611	2.04e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PIICGBBI_00612	7.58e-67	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PIICGBBI_00613	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PIICGBBI_00614	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PIICGBBI_00615	6.39e-102	uspA	-	-	T	-	-	-	universal stress protein
PIICGBBI_00616	1.41e-49	-	-	-	-	-	-	-	-
PIICGBBI_00617	1.18e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PIICGBBI_00618	9.44e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PIICGBBI_00619	1.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIICGBBI_00620	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIICGBBI_00621	1.29e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIICGBBI_00622	4.62e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIICGBBI_00623	1.56e-165	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIICGBBI_00624	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIICGBBI_00625	2.55e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PIICGBBI_00626	1.83e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PIICGBBI_00627	2.34e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PIICGBBI_00628	2.03e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PIICGBBI_00629	1.82e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PIICGBBI_00630	6.61e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
PIICGBBI_00631	1.45e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PIICGBBI_00632	4.84e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
PIICGBBI_00633	3.95e-93	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PIICGBBI_00634	5.41e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIICGBBI_00635	1.32e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PIICGBBI_00636	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIICGBBI_00637	8e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIICGBBI_00638	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIICGBBI_00639	4.93e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIICGBBI_00640	1.71e-182	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIICGBBI_00641	1.02e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIICGBBI_00642	5.9e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIICGBBI_00643	4.09e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIICGBBI_00644	9.12e-56	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PIICGBBI_00645	9.44e-191	ylmH	-	-	S	-	-	-	S4 domain protein
PIICGBBI_00646	1.18e-141	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PIICGBBI_00647	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIICGBBI_00648	8.09e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PIICGBBI_00649	1.73e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PIICGBBI_00650	4.49e-42	-	-	-	-	-	-	-	-
PIICGBBI_00651	2.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIICGBBI_00652	1.47e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PIICGBBI_00653	1.62e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIICGBBI_00654	1.58e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
PIICGBBI_00655	2.93e-150	-	-	-	S	-	-	-	repeat protein
PIICGBBI_00656	2.14e-266	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIICGBBI_00657	0.0	-	-	-	L	-	-	-	Nuclease-related domain
PIICGBBI_00658	1.29e-233	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PIICGBBI_00659	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIICGBBI_00660	3.13e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PIICGBBI_00661	2.52e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIICGBBI_00662	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PIICGBBI_00663	7.42e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PIICGBBI_00664	4.73e-69	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PIICGBBI_00665	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PIICGBBI_00666	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIICGBBI_00667	1.37e-246	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PIICGBBI_00668	2.44e-128	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PIICGBBI_00669	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PIICGBBI_00670	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PIICGBBI_00671	3.78e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PIICGBBI_00672	4.08e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIICGBBI_00673	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIICGBBI_00674	1.45e-195	-	-	-	-	-	-	-	-
PIICGBBI_00675	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIICGBBI_00676	1.43e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIICGBBI_00677	8.42e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIICGBBI_00678	1.17e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PIICGBBI_00679	7.3e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIICGBBI_00680	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PIICGBBI_00681	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIICGBBI_00682	1.39e-106	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIICGBBI_00683	5.48e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIICGBBI_00684	4.63e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIICGBBI_00685	1.23e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIICGBBI_00686	2.42e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIICGBBI_00687	1.23e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIICGBBI_00688	8.12e-262	pbpX1	-	-	V	-	-	-	Beta-lactamase
PIICGBBI_00689	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PIICGBBI_00690	1.18e-55	-	-	-	C	-	-	-	FMN_bind
PIICGBBI_00691	1.01e-104	-	-	-	-	-	-	-	-
PIICGBBI_00692	0.0	-	-	-	-	-	-	-	-
PIICGBBI_00693	2.64e-165	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
PIICGBBI_00694	3.58e-48	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
PIICGBBI_00695	5.52e-24	adhC	1.1.1.90	-	C	ko:K00055,ko:K06898	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	S-(hydroxymethyl)glutathione dehydrogenase activity
PIICGBBI_00696	8.04e-188	-	-	-	-	-	-	-	-
PIICGBBI_00700	3.79e-306	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_00701	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_00702	3.69e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PIICGBBI_00703	1.01e-111	yfhC	-	-	C	-	-	-	Nitroreductase family
PIICGBBI_00704	4.93e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PIICGBBI_00705	2.48e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIICGBBI_00706	1.19e-194	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIICGBBI_00707	2.64e-128	-	-	-	I	-	-	-	PAP2 superfamily
PIICGBBI_00708	1.47e-244	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIICGBBI_00710	2.59e-229	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIICGBBI_00711	1.09e-34	-	-	-	-	-	-	-	-
PIICGBBI_00712	2.31e-128	-	-	-	-	-	-	-	-
PIICGBBI_00713	0.000281	-	-	-	-	-	-	-	-
PIICGBBI_00714	9.27e-75	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PIICGBBI_00715	2.16e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_00716	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PIICGBBI_00717	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIICGBBI_00718	3.62e-121	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIICGBBI_00719	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PIICGBBI_00720	1.03e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIICGBBI_00721	2.07e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIICGBBI_00722	3.65e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_00723	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIICGBBI_00724	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PIICGBBI_00725	0.0	-	-	-	M	-	-	-	domain protein
PIICGBBI_00726	5.14e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PIICGBBI_00727	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIICGBBI_00728	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PIICGBBI_00729	7.54e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
PIICGBBI_00730	7.35e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PIICGBBI_00731	2.76e-60	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PIICGBBI_00732	6.24e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PIICGBBI_00733	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PIICGBBI_00734	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PIICGBBI_00735	6.03e-19	-	-	-	-	-	-	-	-
PIICGBBI_00736	1.14e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PIICGBBI_00737	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_00738	4.42e-124	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PIICGBBI_00739	2.09e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
PIICGBBI_00740	5.21e-71	-	-	-	-	-	-	-	-
PIICGBBI_00741	1.56e-228	citR	-	-	K	-	-	-	Putative sugar-binding domain
PIICGBBI_00742	3.82e-312	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIICGBBI_00743	7.54e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIICGBBI_00744	1.32e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PIICGBBI_00745	1.17e-65	-	-	-	-	-	-	-	-
PIICGBBI_00746	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIICGBBI_00747	2.56e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIICGBBI_00748	1.43e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PIICGBBI_00749	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIICGBBI_00750	9.94e-287	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIICGBBI_00751	1.03e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIICGBBI_00752	2.72e-197	-	-	-	S	-	-	-	reductase
PIICGBBI_00753	3.29e-193	yxeH	-	-	S	-	-	-	hydrolase
PIICGBBI_00754	2.31e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIICGBBI_00755	5.04e-298	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PIICGBBI_00756	4.52e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
PIICGBBI_00757	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIICGBBI_00758	3.01e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIICGBBI_00759	2.94e-280	oatA	-	-	I	-	-	-	Acyltransferase
PIICGBBI_00760	6.51e-113	oatA	-	-	I	-	-	-	Acyltransferase
PIICGBBI_00761	6.35e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIICGBBI_00762	1.5e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PIICGBBI_00763	2.25e-45	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PIICGBBI_00764	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PIICGBBI_00765	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PIICGBBI_00766	3.9e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PIICGBBI_00767	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PIICGBBI_00768	7.76e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIICGBBI_00769	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PIICGBBI_00770	1e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PIICGBBI_00771	2.19e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PIICGBBI_00772	6.56e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIICGBBI_00773	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIICGBBI_00774	5.75e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIICGBBI_00775	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIICGBBI_00776	5.91e-120	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIICGBBI_00777	7.33e-71	-	-	-	M	-	-	-	Lysin motif
PIICGBBI_00778	1.28e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PIICGBBI_00779	4.07e-270	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PIICGBBI_00780	3.15e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PIICGBBI_00781	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIICGBBI_00782	2.22e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PIICGBBI_00783	1.3e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIICGBBI_00784	1.35e-282	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIICGBBI_00785	4.94e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PIICGBBI_00786	6.16e-143	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIICGBBI_00787	9.2e-20	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIICGBBI_00788	1.64e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PIICGBBI_00789	1.45e-229	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PIICGBBI_00790	8.81e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIICGBBI_00791	8.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIICGBBI_00792	1.07e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PIICGBBI_00793	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIICGBBI_00794	2.09e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIICGBBI_00795	2.27e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
PIICGBBI_00796	3.29e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIICGBBI_00797	4.61e-308	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIICGBBI_00798	7.16e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PIICGBBI_00799	6.47e-33	-	-	-	-	-	-	-	-
PIICGBBI_00800	1.43e-36	-	-	-	-	-	-	-	-
PIICGBBI_00801	4.82e-296	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_00802	1.25e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIICGBBI_00803	2.82e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PIICGBBI_00804	7.42e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIICGBBI_00805	9.18e-83	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIICGBBI_00806	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PIICGBBI_00807	0.0	-	-	-	E	-	-	-	Amino acid permease
PIICGBBI_00808	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PIICGBBI_00809	1.13e-312	ynbB	-	-	P	-	-	-	aluminum resistance
PIICGBBI_00810	6.35e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
PIICGBBI_00811	7.3e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
PIICGBBI_00812	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PIICGBBI_00813	5.98e-105	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_00814	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PIICGBBI_00815	4.33e-234	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
PIICGBBI_00816	8.43e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
PIICGBBI_00817	5.22e-89	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIICGBBI_00818	1.71e-265	-	-	-	V	-	-	-	Beta-lactamase
PIICGBBI_00819	2.42e-201	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PIICGBBI_00820	2.46e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PIICGBBI_00821	1.84e-281	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PIICGBBI_00822	5.05e-313	-	-	-	-	-	-	-	-
PIICGBBI_00823	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_00824	2.78e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PIICGBBI_00825	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIICGBBI_00826	5.68e-165	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIICGBBI_00827	5.84e-129	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_00828	7.57e-211	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIICGBBI_00829	2.61e-19	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_00830	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_00831	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_00832	7.71e-172	-	-	-	K	-	-	-	AraC-like ligand binding domain
PIICGBBI_00833	0.0	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PIICGBBI_00834	1.55e-303	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
PIICGBBI_00835	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIICGBBI_00836	1.37e-77	-	-	-	-	-	-	-	-
PIICGBBI_00837	1.06e-63	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PIICGBBI_00838	3.55e-35	-	-	-	-	-	-	-	-
PIICGBBI_00839	3.35e-107	-	-	-	-	-	-	-	-
PIICGBBI_00840	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PIICGBBI_00842	4.4e-254	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
PIICGBBI_00843	1.38e-160	-	-	-	G	-	-	-	Peptidase_C39 like family
PIICGBBI_00844	3.33e-230	-	-	-	M	-	-	-	NlpC/P60 family
PIICGBBI_00845	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_00846	1.63e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIICGBBI_00847	1.07e-178	-	-	-	-	-	-	-	-
PIICGBBI_00848	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PIICGBBI_00849	4.92e-72	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PIICGBBI_00851	5.23e-52	-	-	-	C	-	-	-	Aldo/keto reductase family
PIICGBBI_00852	1.67e-92	-	-	-	C	-	-	-	Aldo/keto reductase family
PIICGBBI_00853	4.13e-68	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PIICGBBI_00854	4.26e-109	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIICGBBI_00855	2.14e-281	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PIICGBBI_00856	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PIICGBBI_00857	3.41e-257	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PIICGBBI_00858	2.31e-146	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PIICGBBI_00859	2.19e-144	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
PIICGBBI_00860	5.65e-56	-	-	-	H	-	-	-	RibD C-terminal domain
PIICGBBI_00861	2.73e-45	-	-	-	-	-	-	-	-
PIICGBBI_00863	2.42e-246	-	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_00864	9.82e-67	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIICGBBI_00865	1.21e-69	-	-	-	GM	-	-	-	NmrA-like family
PIICGBBI_00866	9.06e-62	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
PIICGBBI_00867	1.72e-208	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
PIICGBBI_00868	5.93e-149	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
PIICGBBI_00869	5.96e-205	-	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_00870	6.27e-215	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
PIICGBBI_00871	1.08e-212	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PIICGBBI_00872	1.31e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
PIICGBBI_00873	5.42e-275	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_00874	1.7e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIICGBBI_00877	2.77e-134	-	-	-	-	-	-	-	-
PIICGBBI_00878	2.07e-102	-	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_00879	8.07e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIICGBBI_00880	3.34e-211	-	-	-	S	-	-	-	reductase
PIICGBBI_00881	1.13e-219	-	-	-	-	-	-	-	-
PIICGBBI_00882	4.2e-42	lysR	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_00883	3.25e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
PIICGBBI_00884	2.48e-131	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_00885	6.13e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_00886	9.79e-133	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_00887	2.66e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIICGBBI_00888	1.72e-142	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PIICGBBI_00889	1.81e-223	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PIICGBBI_00890	5.1e-43	-	-	-	-	-	-	-	-
PIICGBBI_00891	1.41e-141	-	-	-	-	-	-	-	-
PIICGBBI_00892	3.18e-140	-	-	-	-	-	-	-	-
PIICGBBI_00893	3.18e-167	-	-	-	F	-	-	-	glutamine amidotransferase
PIICGBBI_00894	3.25e-273	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIICGBBI_00895	1.7e-199	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PIICGBBI_00896	2.53e-152	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PIICGBBI_00897	2.43e-100	-	-	-	-	-	-	-	-
PIICGBBI_00898	1.24e-113	-	-	-	FG	-	-	-	HIT domain
PIICGBBI_00899	5.21e-82	-	-	-	-	-	-	-	-
PIICGBBI_00900	4.91e-121	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIICGBBI_00901	1.62e-135	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PIICGBBI_00902	6.2e-131	-	-	-	-	-	-	-	-
PIICGBBI_00903	1.22e-103	-	-	-	-	-	-	-	-
PIICGBBI_00904	2.72e-188	-	-	-	F	-	-	-	Phosphorylase superfamily
PIICGBBI_00905	3.34e-139	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
PIICGBBI_00906	2.07e-189	-	-	-	F	-	-	-	Phosphorylase superfamily
PIICGBBI_00907	2.06e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
PIICGBBI_00908	1.79e-144	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
PIICGBBI_00909	1.24e-47	-	-	-	-	-	-	-	-
PIICGBBI_00910	2.58e-67	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PIICGBBI_00911	9.6e-137	-	-	-	-	-	-	-	-
PIICGBBI_00912	8.78e-52	-	-	-	-	-	-	-	-
PIICGBBI_00913	3.77e-216	mleR	-	-	K	-	-	-	LysR family
PIICGBBI_00914	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PIICGBBI_00915	3.74e-130	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIICGBBI_00916	2.2e-310	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
PIICGBBI_00917	2.27e-248	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIICGBBI_00918	5.33e-147	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
PIICGBBI_00919	1.23e-278	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PIICGBBI_00920	3.03e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIICGBBI_00921	2.55e-118	-	-	-	L	-	-	-	nuclease
PIICGBBI_00922	2.51e-198	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PIICGBBI_00923	2.81e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PIICGBBI_00924	5.39e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PIICGBBI_00925	4.4e-138	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PIICGBBI_00926	6.01e-54	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PIICGBBI_00927	3.16e-190	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PIICGBBI_00928	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate carboxylase activity
PIICGBBI_00929	0.0	-	-	-	-	-	-	-	-
PIICGBBI_00930	0.0	-	-	-	-	-	-	-	-
PIICGBBI_00931	2.29e-224	yobV3	-	-	K	-	-	-	WYL domain
PIICGBBI_00932	4.35e-108	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
PIICGBBI_00933	1.95e-117	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
PIICGBBI_00934	3.78e-72	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PIICGBBI_00935	1.16e-148	-	-	-	C	-	-	-	Aldo/keto reductase family
PIICGBBI_00936	7.12e-80	-	-	-	C	-	-	-	aldo keto reductase
PIICGBBI_00937	1.54e-187	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
PIICGBBI_00938	1.51e-24	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_00940	9.87e-139	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_00941	2.88e-130	-	-	-	P	-	-	-	esterase
PIICGBBI_00942	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PIICGBBI_00943	3.77e-32	-	-	-	-	-	-	-	-
PIICGBBI_00944	1.29e-182	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_00945	1.74e-125	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
PIICGBBI_00946	3.1e-30	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_00947	1.39e-190	-	-	-	P	-	-	-	FAD-binding domain
PIICGBBI_00948	2.54e-101	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PIICGBBI_00950	0.0	yagE	-	-	E	-	-	-	amino acid
PIICGBBI_00951	1.37e-15	-	-	-	S	-	-	-	Alpha beta hydrolase
PIICGBBI_00952	6e-59	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIICGBBI_00953	4.13e-18	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIICGBBI_00954	1.43e-24	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
PIICGBBI_00955	8.53e-215	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PIICGBBI_00956	1.17e-130	-	-	-	-	-	-	-	-
PIICGBBI_00957	1.9e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIICGBBI_00958	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIICGBBI_00959	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIICGBBI_00960	3.72e-237	-	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_00961	3.65e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PIICGBBI_00962	7.02e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIICGBBI_00963	9.73e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
PIICGBBI_00964	4.78e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PIICGBBI_00965	3.46e-87	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PIICGBBI_00967	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_00968	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_00969	1.74e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PIICGBBI_00970	1.06e-110	rmaD	-	-	K	-	-	-	transcriptional
PIICGBBI_00971	3.92e-76	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIICGBBI_00972	3.43e-07	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIICGBBI_00973	2.71e-256	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIICGBBI_00974	2.62e-138	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
PIICGBBI_00975	1.27e-119	flaR	-	-	F	-	-	-	topology modulation protein
PIICGBBI_00976	1.03e-100	-	-	-	-	-	-	-	-
PIICGBBI_00977	5.95e-250	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PIICGBBI_00978	5.07e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
PIICGBBI_00979	2.95e-87	-	-	-	-	-	-	-	-
PIICGBBI_00980	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PIICGBBI_00981	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PIICGBBI_00982	2.05e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PIICGBBI_00983	2.88e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIICGBBI_00984	6.23e-113	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIICGBBI_00985	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PIICGBBI_00986	2.01e-310	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIICGBBI_00987	2.39e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PIICGBBI_00988	2.83e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIICGBBI_00989	1.61e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PIICGBBI_00990	1.99e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIICGBBI_00991	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PIICGBBI_00992	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIICGBBI_00993	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PIICGBBI_00994	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PIICGBBI_00995	8.23e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PIICGBBI_00996	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PIICGBBI_00997	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PIICGBBI_00998	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PIICGBBI_00999	6.78e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
PIICGBBI_01000	3.39e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PIICGBBI_01001	1.64e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PIICGBBI_01002	2.09e-242	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIICGBBI_01003	1.01e-187	-	-	-	K	-	-	-	SIS domain
PIICGBBI_01004	1.18e-140	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIICGBBI_01005	3.39e-72	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIICGBBI_01006	1.14e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIICGBBI_01007	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PIICGBBI_01008	1.05e-228	-	-	-	-	-	-	-	-
PIICGBBI_01009	1.57e-181	-	-	-	-	-	-	-	-
PIICGBBI_01010	1.72e-123	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PIICGBBI_01011	1.04e-37	-	-	-	-	-	-	-	-
PIICGBBI_01012	3.64e-175	-	-	-	-	-	-	-	-
PIICGBBI_01013	2.03e-186	-	-	-	-	-	-	-	-
PIICGBBI_01014	1.51e-174	-	-	-	-	-	-	-	-
PIICGBBI_01015	1.09e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIICGBBI_01016	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PIICGBBI_01017	7.64e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PIICGBBI_01018	3.45e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIICGBBI_01019	4.48e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PIICGBBI_01020	1.87e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIICGBBI_01021	1.51e-160	-	-	-	S	-	-	-	Peptidase family M23
PIICGBBI_01022	3.01e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIICGBBI_01023	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIICGBBI_01024	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PIICGBBI_01025	2.48e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PIICGBBI_01026	5.41e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PIICGBBI_01027	6.28e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIICGBBI_01028	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIICGBBI_01029	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PIICGBBI_01030	1.79e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PIICGBBI_01031	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PIICGBBI_01032	7.77e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIICGBBI_01033	3.22e-133	-	-	-	S	-	-	-	Peptidase family M23
PIICGBBI_01034	6.31e-144	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIICGBBI_01035	2.17e-209	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIICGBBI_01036	1.4e-157	-	-	-	-	-	-	-	-
PIICGBBI_01037	4.72e-206	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIICGBBI_01038	1.58e-282	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PIICGBBI_01039	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PIICGBBI_01040	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PIICGBBI_01041	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PIICGBBI_01042	3.65e-28	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
PIICGBBI_01043	1.92e-141	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PIICGBBI_01044	1.6e-43	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
PIICGBBI_01045	0.0	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
PIICGBBI_01046	2.86e-05	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
PIICGBBI_01047	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PIICGBBI_01048	5.4e-282	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIICGBBI_01049	0.0	-	-	-	-	-	-	-	-
PIICGBBI_01050	3.69e-157	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
PIICGBBI_01051	8.29e-129	-	-	-	-	-	-	-	-
PIICGBBI_01052	1.82e-139	-	-	-	K	-	-	-	LysR substrate binding domain
PIICGBBI_01053	8.62e-22	-	-	-	-	-	-	-	-
PIICGBBI_01054	2.67e-90	-	-	-	S	-	-	-	Sterol carrier protein domain
PIICGBBI_01055	4.29e-178	-	-	-	S	-	-	-	Sterol carrier protein domain
PIICGBBI_01056	3.83e-127	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PIICGBBI_01057	3.72e-201	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PIICGBBI_01058	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PIICGBBI_01059	1.19e-113	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
PIICGBBI_01060	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIICGBBI_01061	3.52e-27	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PIICGBBI_01062	1.94e-154	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PIICGBBI_01063	1.73e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PIICGBBI_01064	1.72e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PIICGBBI_01065	6.15e-194	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PIICGBBI_01067	7.02e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIICGBBI_01068	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIICGBBI_01069	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PIICGBBI_01070	6.07e-155	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PIICGBBI_01071	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIICGBBI_01072	5.85e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIICGBBI_01073	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PIICGBBI_01074	7.55e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIICGBBI_01075	2.1e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIICGBBI_01076	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PIICGBBI_01077	2.49e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PIICGBBI_01078	8.54e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIICGBBI_01079	9.65e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIICGBBI_01080	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIICGBBI_01081	3.95e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
PIICGBBI_01082	6.47e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PIICGBBI_01083	3.76e-268	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PIICGBBI_01084	2.39e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PIICGBBI_01085	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIICGBBI_01086	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIICGBBI_01087	1.35e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PIICGBBI_01088	1.89e-188	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PIICGBBI_01089	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIICGBBI_01090	2.53e-114	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIICGBBI_01091	2.38e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PIICGBBI_01092	1.45e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIICGBBI_01093	2.05e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PIICGBBI_01094	6.34e-255	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PIICGBBI_01095	1.59e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PIICGBBI_01096	9.32e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PIICGBBI_01097	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIICGBBI_01098	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_01099	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_01100	3.18e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PIICGBBI_01101	2.97e-50	ynzC	-	-	S	-	-	-	UPF0291 protein
PIICGBBI_01102	2.83e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIICGBBI_01103	1.4e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PIICGBBI_01104	1.19e-156	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PIICGBBI_01105	2.58e-226	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PIICGBBI_01106	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PIICGBBI_01107	3.52e-91	-	-	-	S	-	-	-	GtrA-like protein
PIICGBBI_01108	2.28e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIICGBBI_01109	5.01e-164	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PIICGBBI_01110	1.07e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIICGBBI_01111	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PIICGBBI_01112	1.9e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIICGBBI_01113	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIICGBBI_01114	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
PIICGBBI_01115	1.16e-88	-	-	-	-	-	-	-	-
PIICGBBI_01116	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIICGBBI_01117	1.12e-228	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIICGBBI_01118	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PIICGBBI_01119	4.48e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIICGBBI_01120	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_01121	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_01122	5.84e-202	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01123	1.28e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_01124	8.73e-234	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_01125	1.43e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_01126	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIICGBBI_01127	3.16e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIICGBBI_01128	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIICGBBI_01129	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PIICGBBI_01130	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PIICGBBI_01131	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PIICGBBI_01132	1.5e-68	-	-	-	-	-	-	-	-
PIICGBBI_01133	3.29e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PIICGBBI_01134	5.27e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PIICGBBI_01135	1.37e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIICGBBI_01136	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PIICGBBI_01137	9.79e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PIICGBBI_01138	9.29e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIICGBBI_01139	1.08e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIICGBBI_01140	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIICGBBI_01141	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIICGBBI_01142	2.53e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PIICGBBI_01143	2.88e-105	-	-	-	S	-	-	-	ASCH
PIICGBBI_01144	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PIICGBBI_01145	1.52e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PIICGBBI_01146	1.84e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIICGBBI_01147	3.76e-48	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIICGBBI_01148	5.86e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIICGBBI_01149	5.91e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIICGBBI_01150	1.28e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIICGBBI_01151	2.57e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PIICGBBI_01152	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIICGBBI_01153	3.69e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIICGBBI_01154	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PIICGBBI_01155	4.8e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PIICGBBI_01156	3.54e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIICGBBI_01157	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PIICGBBI_01158	3.98e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PIICGBBI_01159	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PIICGBBI_01160	4.41e-137	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PIICGBBI_01161	9.64e-141	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PIICGBBI_01162	7.45e-09	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_01163	9.58e-80	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_01164	7.38e-127	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIICGBBI_01165	3.88e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
PIICGBBI_01166	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PIICGBBI_01167	3.04e-198	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PIICGBBI_01168	3.74e-244	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIICGBBI_01170	2.44e-210	-	-	-	S	-	-	-	Membrane
PIICGBBI_01171	1.75e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
PIICGBBI_01172	4.8e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PIICGBBI_01173	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_01174	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_01175	4.33e-194	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIICGBBI_01176	0.0	-	-	-	-	-	-	-	-
PIICGBBI_01177	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PIICGBBI_01178	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
PIICGBBI_01179	0.0	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_01180	7.89e-213	-	2.7.1.85	-	GK	ko:K18673	-	ko00000,ko01000	ROK family
PIICGBBI_01181	3.58e-262	xylR	-	-	GK	-	-	-	ROK family
PIICGBBI_01182	4.19e-302	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_01183	9.35e-128	-	-	-	S	-	-	-	Bacterial PH domain
PIICGBBI_01184	3.5e-22	-	-	-	-	-	-	-	-
PIICGBBI_01185	1.02e-85	-	-	-	K	-	-	-	sequence-specific DNA binding
PIICGBBI_01186	2.45e-63	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
PIICGBBI_01187	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIICGBBI_01188	1.67e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PIICGBBI_01189	2.43e-62	-	-	-	-	-	-	-	-
PIICGBBI_01190	1.01e-191	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PIICGBBI_01191	0.0	-	-	-	-	-	-	-	-
PIICGBBI_01192	2.73e-07	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PIICGBBI_01193	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PIICGBBI_01194	2.85e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PIICGBBI_01195	5.02e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIICGBBI_01196	3.43e-235	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PIICGBBI_01197	1.75e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIICGBBI_01198	1.94e-215	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIICGBBI_01199	7.44e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIICGBBI_01200	2.73e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIICGBBI_01201	5.47e-88	-	-	-	GM	-	-	-	NmrA-like family
PIICGBBI_01202	1.18e-46	-	-	-	GM	-	-	-	NmrA-like family
PIICGBBI_01203	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIICGBBI_01204	9.28e-317	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIICGBBI_01205	1.86e-141	-	-	-	O	-	-	-	Matrixin
PIICGBBI_01206	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIICGBBI_01207	3.89e-122	-	-	-	K	-	-	-	acetyltransferase
PIICGBBI_01208	1.65e-66	-	-	-	-	-	-	-	-
PIICGBBI_01209	2.34e-204	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIICGBBI_01210	2.87e-62	-	-	-	-	-	-	-	-
PIICGBBI_01211	7.22e-161	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PIICGBBI_01212	2.88e-69	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PIICGBBI_01213	2.66e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIICGBBI_01214	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_01216	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PIICGBBI_01217	7.81e-82	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PIICGBBI_01218	3.88e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PIICGBBI_01219	1.77e-150	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PIICGBBI_01220	2.97e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIICGBBI_01221	6.71e-153	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PIICGBBI_01223	1.3e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PIICGBBI_01224	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
PIICGBBI_01227	2.26e-267	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
PIICGBBI_01228	1.63e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PIICGBBI_01229	8.74e-192	-	-	-	T	-	-	-	EAL domain
PIICGBBI_01230	8.31e-313	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
PIICGBBI_01231	3.07e-119	-	-	-	-	-	-	-	-
PIICGBBI_01232	9.37e-227	-	-	-	C	-	-	-	Oxidoreductase
PIICGBBI_01234	4.69e-271	-	-	-	L	ko:K07496	-	ko00000	TIGRFAM transposase, IS605 OrfB family
PIICGBBI_01235	4.27e-37	-	-	-	C	-	-	-	pentaerythritol trinitrate reductase activity
PIICGBBI_01236	4.83e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
PIICGBBI_01237	2.86e-19	-	-	-	-	-	-	-	-
PIICGBBI_01238	0.0	potE	-	-	E	-	-	-	Amino Acid
PIICGBBI_01239	2.05e-163	-	-	-	S	-	-	-	Alpha beta hydrolase
PIICGBBI_01241	1.31e-165	-	-	-	-	-	-	-	-
PIICGBBI_01242	5.44e-163	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
PIICGBBI_01243	8.84e-93	-	-	-	O	-	-	-	OsmC-like protein
PIICGBBI_01244	3.65e-272	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIICGBBI_01245	9.45e-298	sptS	-	-	T	-	-	-	Histidine kinase
PIICGBBI_01246	1.28e-152	dltr	-	-	K	-	-	-	response regulator
PIICGBBI_01247	4.2e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PIICGBBI_01248	7.55e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PIICGBBI_01249	1.31e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PIICGBBI_01250	8.2e-81	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PIICGBBI_01251	1.63e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PIICGBBI_01252	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PIICGBBI_01253	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIICGBBI_01254	3.33e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_01255	3.56e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01256	3.28e-199	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01257	6.26e-309	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIICGBBI_01258	7.27e-206	lacR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIICGBBI_01259	2.78e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PIICGBBI_01260	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PIICGBBI_01261	4.02e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PIICGBBI_01262	9.46e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
PIICGBBI_01263	1.53e-61	-	-	-	-	-	-	-	-
PIICGBBI_01265	3.46e-53	-	-	-	C	-	-	-	FMN binding
PIICGBBI_01266	1.42e-215	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_01267	4.57e-245	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PIICGBBI_01268	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PIICGBBI_01269	4.34e-282	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIICGBBI_01270	9.91e-241	-	-	-	M	-	-	-	domain protein
PIICGBBI_01271	1.51e-145	-	-	-	-	-	-	-	-
PIICGBBI_01272	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PIICGBBI_01273	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PIICGBBI_01274	1.46e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PIICGBBI_01275	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PIICGBBI_01276	8.15e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PIICGBBI_01277	2.96e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PIICGBBI_01278	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
PIICGBBI_01279	3.37e-245	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PIICGBBI_01280	2.88e-223	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PIICGBBI_01281	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain
PIICGBBI_01282	2e-79	-	-	-	G	-	-	-	polysaccharide catabolic process
PIICGBBI_01283	1.17e-101	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
PIICGBBI_01284	4.63e-225	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIICGBBI_01285	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_01286	5.47e-199	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIICGBBI_01287	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
PIICGBBI_01288	1.05e-225	-	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
PIICGBBI_01289	8.27e-190	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIICGBBI_01290	1.22e-08	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIICGBBI_01291	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIICGBBI_01292	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIICGBBI_01293	1.11e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIICGBBI_01294	0.0	-	-	-	G	-	-	-	isomerase
PIICGBBI_01295	9.9e-240	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
PIICGBBI_01296	5.73e-202	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
PIICGBBI_01297	2.68e-225	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
PIICGBBI_01298	0.0	glpK3	2.7.1.30	-	G	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
PIICGBBI_01299	1.12e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIICGBBI_01300	8.07e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PIICGBBI_01303	2.37e-210	-	-	-	-	-	-	-	-
PIICGBBI_01304	5.77e-214	-	-	-	-	-	-	-	-
PIICGBBI_01305	7.72e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01306	7.05e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PIICGBBI_01307	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PIICGBBI_01308	4.04e-304	ynbB	-	-	P	-	-	-	aluminum resistance
PIICGBBI_01309	1.17e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIICGBBI_01310	1.48e-90	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PIICGBBI_01311	4.01e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PIICGBBI_01312	4.62e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
PIICGBBI_01313	3.23e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIICGBBI_01314	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PIICGBBI_01315	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIICGBBI_01316	0.0	-	-	-	S	-	-	-	membrane
PIICGBBI_01317	2.46e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PIICGBBI_01318	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PIICGBBI_01319	1.06e-69	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIICGBBI_01320	3.51e-17	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIICGBBI_01321	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PIICGBBI_01322	1.6e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PIICGBBI_01323	3.63e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIICGBBI_01324	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIICGBBI_01325	2.59e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIICGBBI_01326	7.19e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PIICGBBI_01327	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIICGBBI_01328	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PIICGBBI_01329	1.89e-209	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIICGBBI_01330	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIICGBBI_01331	6.08e-164	csrR	-	-	K	-	-	-	response regulator
PIICGBBI_01332	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PIICGBBI_01333	9.35e-275	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PIICGBBI_01334	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIICGBBI_01335	4.06e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PIICGBBI_01336	2.72e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIICGBBI_01337	4.26e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PIICGBBI_01338	1.66e-120	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PIICGBBI_01339	4.78e-253	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIICGBBI_01340	8.82e-241	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIICGBBI_01341	4.31e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIICGBBI_01342	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PIICGBBI_01343	1.71e-95	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIICGBBI_01344	1.92e-118	-	-	-	-	-	-	-	-
PIICGBBI_01345	1.39e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIICGBBI_01346	2.67e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIICGBBI_01347	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIICGBBI_01348	5.35e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PIICGBBI_01349	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
PIICGBBI_01350	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIICGBBI_01351	5.52e-139	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIICGBBI_01352	6.72e-205	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIICGBBI_01353	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIICGBBI_01354	9.83e-317	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PIICGBBI_01355	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PIICGBBI_01356	3.61e-144	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIICGBBI_01357	3.52e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PIICGBBI_01358	9.52e-113	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIICGBBI_01359	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIICGBBI_01360	1.15e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIICGBBI_01361	1.88e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIICGBBI_01362	1.24e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PIICGBBI_01363	1.85e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIICGBBI_01364	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PIICGBBI_01365	1.9e-160	-	-	-	C	-	-	-	Flavodoxin
PIICGBBI_01366	5.58e-192	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PIICGBBI_01367	2.68e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
PIICGBBI_01368	2.76e-249	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PIICGBBI_01369	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
PIICGBBI_01370	1.42e-226	-	-	-	S	-	-	-	SLAP domain
PIICGBBI_01371	1.16e-145	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIICGBBI_01372	2.2e-68	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIICGBBI_01373	8.87e-304	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
PIICGBBI_01374	2.45e-214	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
PIICGBBI_01375	8.93e-135	-	-	-	S	-	-	-	Membrane
PIICGBBI_01376	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_01377	0.0	-	-	-	G	ko:K02755,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_01378	2.24e-41	-	2.7.1.208, 2.7.1.211	-	G	ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PIICGBBI_01379	2.69e-191	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIICGBBI_01380	0.0	-	-	-	-	-	-	-	-
PIICGBBI_01381	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PIICGBBI_01382	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIICGBBI_01383	5.52e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
PIICGBBI_01384	9.15e-165	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIICGBBI_01385	3.37e-273	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PIICGBBI_01386	3.15e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01387	1.38e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PIICGBBI_01388	3.51e-74	-	-	-	-	-	-	-	-
PIICGBBI_01389	3.26e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIICGBBI_01390	3.19e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIICGBBI_01391	0.0	yhaN	-	-	L	-	-	-	AAA domain
PIICGBBI_01392	8.31e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PIICGBBI_01393	6.93e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PIICGBBI_01394	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PIICGBBI_01395	3.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PIICGBBI_01396	1.34e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PIICGBBI_01397	2.79e-154	-	-	-	-	-	-	-	-
PIICGBBI_01398	2.45e-246	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
PIICGBBI_01399	8.56e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PIICGBBI_01400	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PIICGBBI_01401	1.06e-164	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PIICGBBI_01402	3.16e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIICGBBI_01403	3.95e-310	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PIICGBBI_01405	1.19e-71	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PIICGBBI_01406	4.1e-251	flp	-	-	V	-	-	-	Beta-lactamase
PIICGBBI_01407	3.16e-72	-	-	-	-	-	-	-	-
PIICGBBI_01408	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
PIICGBBI_01409	4.95e-53	-	-	-	S	-	-	-	Enterocin A Immunity
PIICGBBI_01410	0.0	-	-	-	S	-	-	-	domain, Protein
PIICGBBI_01411	6.41e-105	-	-	-	S	-	-	-	Cupin domain
PIICGBBI_01412	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PIICGBBI_01413	1.39e-22	-	-	-	K	-	-	-	transcriptional regulator
PIICGBBI_01414	3.3e-94	-	-	-	K	-	-	-	transcriptional regulator
PIICGBBI_01416	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIICGBBI_01417	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PIICGBBI_01418	7.75e-153	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PIICGBBI_01419	7.6e-118	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PIICGBBI_01420	1.29e-150	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PIICGBBI_01421	1.42e-34	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PIICGBBI_01422	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_01423	5.35e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIICGBBI_01428	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIICGBBI_01429	1.28e-131	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIICGBBI_01430	1.47e-144	-	-	-	S	-	-	-	SNARE associated Golgi protein
PIICGBBI_01431	1.84e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIICGBBI_01432	4.92e-207	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PIICGBBI_01433	3.62e-121	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PIICGBBI_01434	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PIICGBBI_01435	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PIICGBBI_01436	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
PIICGBBI_01437	6.9e-220	-	-	-	-	-	-	-	-
PIICGBBI_01438	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PIICGBBI_01439	1.8e-124	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIICGBBI_01440	2.62e-198	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIICGBBI_01441	4.16e-201	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PIICGBBI_01442	1.87e-271	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIICGBBI_01443	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
PIICGBBI_01444	1.68e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01445	1.24e-197	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PIICGBBI_01446	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIICGBBI_01447	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIICGBBI_01448	4.53e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PIICGBBI_01449	4e-234	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
PIICGBBI_01450	4.72e-200	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PIICGBBI_01451	7.21e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PIICGBBI_01452	9.54e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PIICGBBI_01453	0.0	-	-	-	M	-	-	-	domain protein
PIICGBBI_01454	3.05e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PIICGBBI_01455	0.0	-	-	-	-	-	-	-	-
PIICGBBI_01456	7.95e-64	-	-	-	-	-	-	-	-
PIICGBBI_01457	9.1e-184	-	-	-	S	-	-	-	PAS domain
PIICGBBI_01458	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIICGBBI_01459	5.44e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIICGBBI_01460	2.91e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PIICGBBI_01461	4.14e-312	-	-	-	T	-	-	-	GHKL domain
PIICGBBI_01462	2.36e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIICGBBI_01463	1.34e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIICGBBI_01464	2.83e-99	yybA	-	-	K	-	-	-	Transcriptional regulator
PIICGBBI_01465	3.59e-123	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PIICGBBI_01466	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIICGBBI_01467	2.28e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PIICGBBI_01468	9.2e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIICGBBI_01469	8.57e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIICGBBI_01470	3.51e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PIICGBBI_01471	1.68e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PIICGBBI_01472	1.25e-106	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PIICGBBI_01473	1.32e-79	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_01475	3.39e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PIICGBBI_01476	1.6e-119	-	-	-	-	-	-	-	-
PIICGBBI_01477	8.44e-201	-	-	-	-	-	-	-	-
PIICGBBI_01478	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PIICGBBI_01479	7.07e-178	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PIICGBBI_01480	1.35e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PIICGBBI_01481	1.25e-22	-	-	-	-	-	-	-	-
PIICGBBI_01482	3.45e-64	-	-	-	-	-	-	-	-
PIICGBBI_01483	3.66e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIICGBBI_01484	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIICGBBI_01485	1.39e-164	-	-	-	-	-	-	-	-
PIICGBBI_01486	7.62e-308	-	-	-	S	-	-	-	response to antibiotic
PIICGBBI_01487	3.02e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01488	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PIICGBBI_01489	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PIICGBBI_01490	1.69e-160	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PIICGBBI_01491	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PIICGBBI_01492	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_01493	1.29e-140	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PIICGBBI_01494	5.37e-90	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIICGBBI_01496	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
PIICGBBI_01497	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
PIICGBBI_01498	5.59e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PIICGBBI_01499	1.56e-256	-	-	-	S	-	-	-	Membrane
PIICGBBI_01500	1.15e-189	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PIICGBBI_01501	7.86e-240	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIICGBBI_01502	3.86e-239	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIICGBBI_01503	1.96e-192	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIICGBBI_01504	1.06e-258	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PIICGBBI_01505	1.24e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIICGBBI_01506	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_01507	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIICGBBI_01508	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIICGBBI_01509	1.78e-204	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIICGBBI_01510	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
PIICGBBI_01512	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
PIICGBBI_01513	4.05e-119	-	-	-	-	-	-	-	-
PIICGBBI_01514	6.91e-235	-	-	-	-	-	-	-	-
PIICGBBI_01515	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
PIICGBBI_01521	1.31e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PIICGBBI_01522	6.89e-280	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIICGBBI_01523	2.52e-84	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PIICGBBI_01524	1.63e-175	-	-	-	L	ko:K07483	-	ko00000	transposase activity
PIICGBBI_01525	1.34e-298	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIICGBBI_01526	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PIICGBBI_01527	1.23e-255	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PIICGBBI_01528	1.86e-287	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PIICGBBI_01529	7.58e-244	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
PIICGBBI_01530	2.37e-149	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIICGBBI_01531	2.65e-215	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
PIICGBBI_01532	4.02e-192	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PIICGBBI_01533	1.77e-159	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
PIICGBBI_01534	6.17e-191	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PIICGBBI_01535	3.43e-165	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PIICGBBI_01536	1.01e-193	epsB	-	-	M	-	-	-	biosynthesis protein
PIICGBBI_01537	5.44e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIICGBBI_01538	2.99e-268	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIICGBBI_01539	5.52e-241	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PIICGBBI_01540	0.0	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
PIICGBBI_01541	1.4e-204	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PIICGBBI_01542	2.99e-176	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PIICGBBI_01543	7.09e-125	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PIICGBBI_01544	6.94e-110	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
PIICGBBI_01545	2.96e-56	-	-	-	-	-	-	-	-
PIICGBBI_01546	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
PIICGBBI_01547	3.86e-142	-	-	-	-	-	-	-	-
PIICGBBI_01548	7.02e-103	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
PIICGBBI_01549	2.71e-233	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIICGBBI_01550	1.36e-105	-	-	-	-	-	-	-	-
PIICGBBI_01551	9.3e-79	-	-	-	S	-	-	-	Peptidase_C39 like family
PIICGBBI_01552	1.62e-48	-	-	-	S	-	-	-	Peptidase_C39 like family
PIICGBBI_01553	1.47e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIICGBBI_01554	1.08e-62	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PIICGBBI_01555	2.73e-46	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PIICGBBI_01556	4.44e-110	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PIICGBBI_01557	8.95e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIICGBBI_01558	0.0	-	-	-	S	-	-	-	ABC transporter
PIICGBBI_01559	3.08e-81	-	-	-	-	-	-	-	-
PIICGBBI_01560	2.7e-59	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIICGBBI_01561	5.01e-293	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIICGBBI_01562	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PIICGBBI_01563	9.86e-59	-	-	-	P	ko:K03449	-	ko00000,ko02000	transmembrane transport
PIICGBBI_01564	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PIICGBBI_01565	1.04e-82	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PIICGBBI_01566	6.99e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PIICGBBI_01567	6.65e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIICGBBI_01568	1.03e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIICGBBI_01569	7.83e-60	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PIICGBBI_01570	3e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIICGBBI_01571	4.7e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIICGBBI_01572	1.18e-163	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PIICGBBI_01573	1.55e-261	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PIICGBBI_01574	1.31e-216	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PIICGBBI_01575	1.05e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PIICGBBI_01576	1.88e-251	-	-	-	S	-	-	-	Fic/DOC family
PIICGBBI_01577	7.39e-276	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIICGBBI_01578	1.6e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01579	2.89e-12	-	-	-	-	-	-	-	-
PIICGBBI_01580	4.14e-89	-	-	-	-	-	-	-	-
PIICGBBI_01581	6.68e-35	-	-	-	-	-	-	-	-
PIICGBBI_01582	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
PIICGBBI_01583	5.61e-115	-	-	-	-	-	-	-	-
PIICGBBI_01584	2.26e-29	-	-	-	-	-	-	-	-
PIICGBBI_01589	1.21e-275	blpT	-	-	-	-	-	-	-
PIICGBBI_01590	3.21e-136	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PIICGBBI_01591	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIICGBBI_01594	7.63e-190	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PIICGBBI_01595	8.09e-298	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PIICGBBI_01596	2e-06	-	-	-	-	-	-	-	-
PIICGBBI_01599	2.6e-141	-	-	-	-	-	-	-	-
PIICGBBI_01601	2.71e-136	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIICGBBI_01602	5.21e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIICGBBI_01603	2.62e-50	-	-	-	S	-	-	-	Enterocin A Immunity
PIICGBBI_01604	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PIICGBBI_01605	9.17e-37	-	-	-	-	-	-	-	-
PIICGBBI_01606	1.47e-45	-	-	-	-	-	-	-	-
PIICGBBI_01607	1.4e-69	-	-	-	S	-	-	-	Enterocin A Immunity
PIICGBBI_01608	5.63e-64	-	-	-	S	-	-	-	Enterocin A Immunity
PIICGBBI_01609	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PIICGBBI_01610	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIICGBBI_01611	9.58e-267	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PIICGBBI_01612	1.44e-157	vanR	-	-	K	-	-	-	response regulator
PIICGBBI_01613	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIICGBBI_01614	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01615	1.55e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PIICGBBI_01616	1.39e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIICGBBI_01617	2.22e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PIICGBBI_01618	2.05e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIICGBBI_01619	4.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PIICGBBI_01620	2.79e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIICGBBI_01621	3.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PIICGBBI_01622	8.5e-105	cvpA	-	-	S	-	-	-	Colicin V production protein
PIICGBBI_01623	6.64e-233	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIICGBBI_01624	1.24e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIICGBBI_01625	6.34e-127	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PIICGBBI_01626	4.14e-126	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PIICGBBI_01627	2.15e-144	-	-	-	K	-	-	-	WHG domain
PIICGBBI_01628	1.59e-49	-	-	-	-	-	-	-	-
PIICGBBI_01629	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIICGBBI_01630	3.26e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01631	1.43e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_01632	1.45e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIICGBBI_01633	2.86e-145	-	-	-	G	-	-	-	phosphoglycerate mutase
PIICGBBI_01634	9.8e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
PIICGBBI_01635	4.33e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PIICGBBI_01636	3.44e-153	-	-	-	-	-	-	-	-
PIICGBBI_01637	3.08e-204	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PIICGBBI_01638	1.71e-282	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PIICGBBI_01639	2.13e-36	-	-	-	-	-	-	-	-
PIICGBBI_01640	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PIICGBBI_01641	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PIICGBBI_01642	7.67e-80	lysM	-	-	M	-	-	-	LysM domain
PIICGBBI_01643	9.68e-226	-	-	-	-	-	-	-	-
PIICGBBI_01644	3e-133	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIICGBBI_01645	8.59e-148	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PIICGBBI_01647	1.97e-280	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PIICGBBI_01648	1.26e-117	ymdB	-	-	S	-	-	-	Macro domain protein
PIICGBBI_01649	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
PIICGBBI_01652	2.49e-189	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_01653	4.05e-12	-	-	-	-	-	-	-	-
PIICGBBI_01654	2.56e-110	-	-	-	-	-	-	-	-
PIICGBBI_01655	8.05e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_01656	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01657	1.35e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIICGBBI_01658	6e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIICGBBI_01659	1.23e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PIICGBBI_01660	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PIICGBBI_01661	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIICGBBI_01662	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PIICGBBI_01663	1.82e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIICGBBI_01664	7.43e-229	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PIICGBBI_01665	7.79e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIICGBBI_01666	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIICGBBI_01667	4.8e-99	-	-	-	-	-	-	-	-
PIICGBBI_01668	1.06e-20	-	-	-	-	-	-	-	-
PIICGBBI_01669	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIICGBBI_01670	6.65e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PIICGBBI_01671	1.23e-83	-	-	-	S	-	-	-	Protein conserved in bacteria
PIICGBBI_01672	9.67e-220	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PIICGBBI_01673	1.91e-171	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PIICGBBI_01674	1.96e-108	-	-	-	M	-	-	-	NlpC/P60 family
PIICGBBI_01675	8.16e-212	-	-	-	EG	-	-	-	EamA-like transporter family
PIICGBBI_01676	1.03e-211	-	-	-	EG	-	-	-	EamA-like transporter family
PIICGBBI_01677	1.41e-209	yicL	-	-	EG	-	-	-	EamA-like transporter family
PIICGBBI_01678	7.08e-137	-	-	-	-	-	-	-	-
PIICGBBI_01679	6.33e-74	-	-	-	-	-	-	-	-
PIICGBBI_01680	1.14e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIICGBBI_01681	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIICGBBI_01682	2.84e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIICGBBI_01685	1.69e-259	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PIICGBBI_01686	4.6e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PIICGBBI_01687	6.65e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PIICGBBI_01688	1.43e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIICGBBI_01689	6.09e-152	-	-	-	K	-	-	-	Rhodanese Homology Domain
PIICGBBI_01690	1.75e-10	-	-	-	-	-	-	-	-
PIICGBBI_01691	1.27e-70	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
PIICGBBI_01692	1e-305	-	-	-	E	-	-	-	amino acid
PIICGBBI_01693	1.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PIICGBBI_01694	2.14e-313	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PIICGBBI_01695	4.27e-293	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PIICGBBI_01696	8.71e-157	-	-	-	-	-	-	-	-
PIICGBBI_01697	1.07e-150	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PIICGBBI_01698	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
PIICGBBI_01699	4.24e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIICGBBI_01700	1e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIICGBBI_01701	8.01e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01702	4.41e-265	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_01703	1.12e-286	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_01704	5.63e-49	-	-	-	-	-	-	-	-
PIICGBBI_01705	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIICGBBI_01706	9.26e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIICGBBI_01707	9.09e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PIICGBBI_01708	2.86e-81	-	-	-	-	-	-	-	-
PIICGBBI_01709	3.4e-228	pbpX2	-	-	V	-	-	-	Beta-lactamase
PIICGBBI_01710	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIICGBBI_01711	2.46e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIICGBBI_01712	1.12e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PIICGBBI_01713	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIICGBBI_01714	2.17e-25	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PIICGBBI_01715	2.18e-53	-	-	-	-	-	-	-	-
PIICGBBI_01716	8.03e-278	-	-	-	S	-	-	-	Membrane
PIICGBBI_01717	1.97e-107	ykuL	-	-	S	-	-	-	(CBS) domain
PIICGBBI_01718	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PIICGBBI_01719	4.69e-262	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
PIICGBBI_01720	2.82e-105	-	-	-	S	-	-	-	Putative adhesin
PIICGBBI_01721	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIICGBBI_01722	1.57e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_01723	5.7e-125	-	-	-	M	-	-	-	CHAP domain
PIICGBBI_01724	1.4e-88	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_01725	2.41e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIICGBBI_01726	3.39e-253	-	-	-	S	-	-	-	DUF218 domain
PIICGBBI_01727	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01728	4.51e-134	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PIICGBBI_01729	1.21e-236	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PIICGBBI_01730	9.41e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PIICGBBI_01731	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PIICGBBI_01732	9.19e-266	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIICGBBI_01733	4.74e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIICGBBI_01734	1.25e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
PIICGBBI_01735	1.19e-175	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIICGBBI_01736	1.63e-152	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PIICGBBI_01737	2.81e-164	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PIICGBBI_01738	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIICGBBI_01739	3.53e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIICGBBI_01740	2.29e-166	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PIICGBBI_01741	4.08e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIICGBBI_01742	3.14e-226	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIICGBBI_01743	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PIICGBBI_01744	8.03e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIICGBBI_01745	2.47e-32	-	-	-	-	-	-	-	-
PIICGBBI_01746	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIICGBBI_01747	6.78e-100	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
PIICGBBI_01748	1.77e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
PIICGBBI_01749	1.09e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
PIICGBBI_01750	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PIICGBBI_01751	2.91e-234	-	-	-	S	-	-	-	DUF218 domain
PIICGBBI_01752	6.11e-168	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
PIICGBBI_01753	6.65e-153	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
PIICGBBI_01754	1.78e-26	-	-	-	-	-	-	-	-
PIICGBBI_01755	5.17e-273	-	-	-	-	-	-	-	-
PIICGBBI_01756	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIICGBBI_01757	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIICGBBI_01758	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIICGBBI_01759	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIICGBBI_01760	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIICGBBI_01761	2.31e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIICGBBI_01762	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIICGBBI_01763	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PIICGBBI_01764	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIICGBBI_01765	4.89e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIICGBBI_01766	6.15e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PIICGBBI_01767	3.1e-269	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIICGBBI_01768	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIICGBBI_01769	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIICGBBI_01770	9.55e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PIICGBBI_01771	8.43e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIICGBBI_01772	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIICGBBI_01773	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PIICGBBI_01774	6.96e-100	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIICGBBI_01775	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PIICGBBI_01776	1e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
PIICGBBI_01777	5.03e-168	degV1	-	-	S	-	-	-	DegV family
PIICGBBI_01778	3.1e-44	degV1	-	-	S	-	-	-	DegV family
PIICGBBI_01779	1.09e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PIICGBBI_01780	1.38e-33	-	-	-	S	-	-	-	CsbD-like
PIICGBBI_01781	1.47e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
PIICGBBI_01782	3.58e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PIICGBBI_01784	7.47e-133	cadD	-	-	P	-	-	-	Cadmium resistance transporter
PIICGBBI_01785	2.41e-77	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PIICGBBI_01786	2.93e-235	-	-	-	-	-	-	-	-
PIICGBBI_01787	1.08e-71	-	-	-	-	-	-	-	-
PIICGBBI_01788	1.46e-263	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PIICGBBI_01789	4.15e-120	-	-	-	-	-	-	-	-
PIICGBBI_01790	1.16e-234	-	-	-	EP	-	-	-	Plasmid replication protein
PIICGBBI_01791	1.45e-42	-	-	-	-	-	-	-	-
PIICGBBI_01792	8.39e-299	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIICGBBI_01793	4.37e-43	-	-	-	-	-	-	-	-
PIICGBBI_01794	4.41e-92	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
PIICGBBI_01795	6.65e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
PIICGBBI_01798	2.01e-205	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
PIICGBBI_01799	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIICGBBI_01800	1.5e-295	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
PIICGBBI_01801	1.4e-196	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PIICGBBI_01802	9.66e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
PIICGBBI_01803	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PIICGBBI_01804	2.97e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PIICGBBI_01805	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
PIICGBBI_01806	2e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
PIICGBBI_01807	2.37e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PIICGBBI_01808	9.67e-22	-	-	-	-	-	-	-	-
PIICGBBI_01809	2.79e-313	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PIICGBBI_01810	6.35e-69	-	-	-	-	-	-	-	-
PIICGBBI_01811	8.29e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01812	3.51e-170	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIICGBBI_01813	3.82e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PIICGBBI_01814	1.29e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PIICGBBI_01815	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PIICGBBI_01816	2.32e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PIICGBBI_01817	9.66e-41	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PIICGBBI_01818	1.63e-172	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PIICGBBI_01819	8.28e-15	-	-	-	S	-	-	-	interspecies interaction between organisms
PIICGBBI_01820	5.27e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIICGBBI_01821	3.08e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PIICGBBI_01822	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PIICGBBI_01823	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIICGBBI_01824	3.73e-65	-	-	-	K	-	-	-	LysR substrate binding domain
PIICGBBI_01825	4.38e-74	-	-	-	S	-	-	-	FMN_bind
PIICGBBI_01826	4.41e-291	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PIICGBBI_01827	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PIICGBBI_01828	1.45e-50	-	-	-	S	-	-	-	Cytochrome B5
PIICGBBI_01829	2.65e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PIICGBBI_01830	1.34e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
PIICGBBI_01831	1.07e-238	-	-	-	M	-	-	-	Glycosyl transferase family 8
PIICGBBI_01832	6.45e-204	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PIICGBBI_01833	1.11e-191	-	-	-	I	-	-	-	Acyl-transferase
PIICGBBI_01834	8.36e-102	-	-	-	-	-	-	-	-
PIICGBBI_01835	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
PIICGBBI_01836	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIICGBBI_01838	9.77e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PIICGBBI_01839	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIICGBBI_01840	0.0	yycH	-	-	S	-	-	-	YycH protein
PIICGBBI_01841	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
PIICGBBI_01842	9.1e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PIICGBBI_01843	4.91e-57	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PIICGBBI_01844	1.78e-180	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PIICGBBI_01845	2.48e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIICGBBI_01846	1.51e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_01848	0.0	-	-	-	S	-	-	-	CAAX protease self-immunity
PIICGBBI_01849	1.98e-26	-	-	-	-	-	-	-	-
PIICGBBI_01850	1.09e-157	-	-	-	-	-	-	-	-
PIICGBBI_01851	8e-226	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIICGBBI_01852	6.92e-130	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PIICGBBI_01853	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01854	2.11e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIICGBBI_01855	8.13e-208	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PIICGBBI_01856	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PIICGBBI_01857	1.37e-248	ysdE	-	-	P	-	-	-	Citrate transporter
PIICGBBI_01858	7.83e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIICGBBI_01859	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PIICGBBI_01860	9.69e-25	-	-	-	-	-	-	-	-
PIICGBBI_01861	2.14e-197	-	-	-	-	-	-	-	-
PIICGBBI_01863	1.08e-288	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
PIICGBBI_01864	2.11e-271	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PIICGBBI_01865	1.07e-157	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PIICGBBI_01866	2.73e-206	-	-	-	L	-	-	-	HNH nucleases
PIICGBBI_01867	1.63e-233	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
PIICGBBI_01868	2.21e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01869	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIICGBBI_01870	3.08e-159	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PIICGBBI_01871	2.29e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PIICGBBI_01872	9.33e-180	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PIICGBBI_01873	1.04e-105	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
PIICGBBI_01874	2.57e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PIICGBBI_01875	9.36e-111	-	-	-	-	-	-	-	-
PIICGBBI_01876	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIICGBBI_01877	1.45e-231	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIICGBBI_01878	2.82e-183	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIICGBBI_01879	5.06e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PIICGBBI_01880	2.63e-204	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PIICGBBI_01881	1.07e-163	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PIICGBBI_01882	1.02e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIICGBBI_01883	1.33e-75	-	-	-	-	-	-	-	-
PIICGBBI_01884	2.83e-62	-	-	-	-	-	-	-	-
PIICGBBI_01885	5.31e-58	-	3.6.4.12	-	-	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	-
PIICGBBI_01886	1.3e-99	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
PIICGBBI_01887	4.33e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIICGBBI_01888	5.66e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIICGBBI_01889	2.93e-173	-	-	-	-	-	-	-	-
PIICGBBI_01890	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIICGBBI_01891	7.42e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIICGBBI_01892	1.96e-293	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PIICGBBI_01893	7.25e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PIICGBBI_01894	1.49e-136	-	-	-	-	-	-	-	-
PIICGBBI_01895	9.78e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PIICGBBI_01896	1.71e-170	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PIICGBBI_01897	2.59e-66	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIICGBBI_01898	5.07e-123	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIICGBBI_01899	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PIICGBBI_01900	8.53e-292	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIICGBBI_01901	2.8e-51	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PIICGBBI_01902	9.7e-39	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PIICGBBI_01903	1.74e-112	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIICGBBI_01904	8.74e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIICGBBI_01905	3.95e-113	usp5	-	-	T	-	-	-	universal stress protein
PIICGBBI_01906	7.56e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PIICGBBI_01907	4.46e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PIICGBBI_01908	2e-171	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01909	4.3e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIICGBBI_01910	7.66e-141	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PIICGBBI_01911	3.65e-109	-	-	-	-	-	-	-	-
PIICGBBI_01912	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIICGBBI_01913	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PIICGBBI_01914	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PIICGBBI_01915	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PIICGBBI_01916	1.29e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIICGBBI_01917	1.6e-127	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIICGBBI_01918	4.3e-297	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PIICGBBI_01919	1.88e-292	yttB	-	-	EGP	-	-	-	Major Facilitator
PIICGBBI_01920	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIICGBBI_01921	1.24e-235	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIICGBBI_01922	3.24e-132	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIICGBBI_01923	6.3e-91	-	-	-	-	-	-	-	-
PIICGBBI_01924	2.15e-21	-	-	-	-	-	-	-	-
PIICGBBI_01925	4.97e-81	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PIICGBBI_01926	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
PIICGBBI_01927	2.3e-229	-	-	-	-	-	-	-	-
PIICGBBI_01929	1.19e-107	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group