ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
DMHIIBIA_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMHIIBIA_00003 8.12e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DMHIIBIA_00004 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
DMHIIBIA_00005 7.52e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMHIIBIA_00006 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
DMHIIBIA_00007 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMHIIBIA_00008 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMHIIBIA_00009 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00012 4.57e-231 yaaC - - S - - - YaaC-like Protein
DMHIIBIA_00013 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DMHIIBIA_00014 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DMHIIBIA_00015 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DMHIIBIA_00016 1.17e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DMHIIBIA_00017 1.85e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMHIIBIA_00018 4.27e-254 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
DMHIIBIA_00020 1.46e-156 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
DMHIIBIA_00021 6.7e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
DMHIIBIA_00022 1.01e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
DMHIIBIA_00023 9.71e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
DMHIIBIA_00024 1.18e-109 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DMHIIBIA_00025 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMHIIBIA_00026 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMHIIBIA_00027 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMHIIBIA_00028 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
DMHIIBIA_00029 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
DMHIIBIA_00030 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00033 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
DMHIIBIA_00034 1.19e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
DMHIIBIA_00035 1.7e-241 yaaN - - P - - - Belongs to the TelA family
DMHIIBIA_00036 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
DMHIIBIA_00037 4.49e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMHIIBIA_00038 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
DMHIIBIA_00039 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
DMHIIBIA_00040 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
DMHIIBIA_00041 9e-189 yaaT - - S - - - stage 0 sporulation protein
DMHIIBIA_00042 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
DMHIIBIA_00043 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
DMHIIBIA_00044 1.16e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
DMHIIBIA_00045 1.58e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMHIIBIA_00046 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
DMHIIBIA_00047 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMHIIBIA_00048 2.49e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
DMHIIBIA_00049 1.38e-307 yabE - - T - - - protein conserved in bacteria
DMHIIBIA_00050 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DMHIIBIA_00051 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DMHIIBIA_00052 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
DMHIIBIA_00053 5.32e-53 veg - - S - - - protein conserved in bacteria
DMHIIBIA_00054 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
DMHIIBIA_00055 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMHIIBIA_00056 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
DMHIIBIA_00057 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
DMHIIBIA_00058 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
DMHIIBIA_00059 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMHIIBIA_00060 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMHIIBIA_00061 7.21e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMHIIBIA_00062 7.09e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DMHIIBIA_00063 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
DMHIIBIA_00064 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMHIIBIA_00065 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
DMHIIBIA_00066 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_00067 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
DMHIIBIA_00068 1.42e-48 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DMHIIBIA_00069 5.47e-66 yabP - - S - - - Sporulation protein YabP
DMHIIBIA_00070 7.93e-133 yabQ - - S - - - spore cortex biosynthesis protein
DMHIIBIA_00071 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
DMHIIBIA_00072 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
DMHIIBIA_00075 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
DMHIIBIA_00076 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DMHIIBIA_00077 1.34e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
DMHIIBIA_00078 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DMHIIBIA_00079 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
DMHIIBIA_00080 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMHIIBIA_00081 9.51e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMHIIBIA_00082 1.3e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DMHIIBIA_00083 1.16e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
DMHIIBIA_00084 3.62e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DMHIIBIA_00085 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMHIIBIA_00086 1.79e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
DMHIIBIA_00087 4.03e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
DMHIIBIA_00088 9.13e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMHIIBIA_00089 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DMHIIBIA_00090 7.88e-116 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMHIIBIA_00091 6.1e-40 yazB - - K - - - transcriptional
DMHIIBIA_00092 1.03e-239 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMHIIBIA_00093 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
DMHIIBIA_00094 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00097 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00100 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
DMHIIBIA_00101 1.89e-82 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
DMHIIBIA_00102 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
DMHIIBIA_00103 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
DMHIIBIA_00104 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DMHIIBIA_00105 8.93e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DMHIIBIA_00106 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
DMHIIBIA_00107 1.01e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DMHIIBIA_00108 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DMHIIBIA_00109 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMHIIBIA_00110 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
DMHIIBIA_00111 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
DMHIIBIA_00112 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DMHIIBIA_00113 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMHIIBIA_00114 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
DMHIIBIA_00115 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
DMHIIBIA_00116 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DMHIIBIA_00117 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
DMHIIBIA_00118 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMHIIBIA_00119 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DMHIIBIA_00120 8.13e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMHIIBIA_00121 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DMHIIBIA_00122 2.95e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
DMHIIBIA_00123 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMHIIBIA_00124 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMHIIBIA_00125 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
DMHIIBIA_00126 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMHIIBIA_00127 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DMHIIBIA_00128 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMHIIBIA_00129 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMHIIBIA_00130 5.06e-234 ybaC - - S - - - Alpha/beta hydrolase family
DMHIIBIA_00131 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
DMHIIBIA_00132 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMHIIBIA_00133 2.59e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
DMHIIBIA_00134 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DMHIIBIA_00135 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMHIIBIA_00136 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMHIIBIA_00137 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMHIIBIA_00138 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMHIIBIA_00139 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMHIIBIA_00140 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
DMHIIBIA_00141 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMHIIBIA_00142 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMHIIBIA_00143 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMHIIBIA_00144 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DMHIIBIA_00145 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMHIIBIA_00146 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DMHIIBIA_00147 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMHIIBIA_00148 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMHIIBIA_00149 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMHIIBIA_00150 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
DMHIIBIA_00151 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
DMHIIBIA_00152 2.59e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DMHIIBIA_00153 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DMHIIBIA_00154 2.71e-181 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
DMHIIBIA_00155 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMHIIBIA_00156 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
DMHIIBIA_00157 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMHIIBIA_00158 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMHIIBIA_00159 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMHIIBIA_00160 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
DMHIIBIA_00161 7.19e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMHIIBIA_00162 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMHIIBIA_00163 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DMHIIBIA_00164 1.69e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DMHIIBIA_00165 6.54e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMHIIBIA_00166 8.64e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
DMHIIBIA_00167 1.69e-183 ybaJ - - Q - - - Methyltransferase domain
DMHIIBIA_00168 3.15e-108 yizA - - S - - - Damage-inducible protein DinB
DMHIIBIA_00169 3.1e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
DMHIIBIA_00170 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DMHIIBIA_00171 6.33e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DMHIIBIA_00172 3.93e-102 gerD - - - ko:K06294 - ko00000 -
DMHIIBIA_00173 1.78e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
DMHIIBIA_00174 7.14e-180 pdaB - - G - - - Polysaccharide deacetylase
DMHIIBIA_00175 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00181 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00191 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00192 1.1e-279 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
DMHIIBIA_00193 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMHIIBIA_00194 1.44e-226 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
DMHIIBIA_00195 6.88e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
DMHIIBIA_00196 6.74e-289 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
DMHIIBIA_00197 2.09e-220 ybaS - - S - - - Na -dependent transporter
DMHIIBIA_00198 6.15e-140 ybbA - - S ko:K07017 - ko00000 Putative esterase
DMHIIBIA_00199 5.83e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_00200 4.42e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_00201 1.73e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
DMHIIBIA_00202 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
DMHIIBIA_00203 3.7e-299 ybbC - - S - - - protein conserved in bacteria
DMHIIBIA_00204 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
DMHIIBIA_00205 1.61e-311 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
DMHIIBIA_00206 1.75e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_00207 6.37e-206 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DMHIIBIA_00208 1.01e-109 ybbJ - - J - - - acetyltransferase
DMHIIBIA_00209 3.89e-101 ybbK - - S - - - Protein of unknown function (DUF523)
DMHIIBIA_00215 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00216 1.85e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
DMHIIBIA_00217 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DMHIIBIA_00218 4.39e-285 ybbR - - S - - - protein conserved in bacteria
DMHIIBIA_00219 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMHIIBIA_00220 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DMHIIBIA_00221 2.05e-197 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
DMHIIBIA_00222 8.23e-138 - - - S - - - ABC-2 family transporter protein
DMHIIBIA_00223 5.29e-125 ybdN - - - - - - -
DMHIIBIA_00224 6.07e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
DMHIIBIA_00225 3.46e-205 dkgB - - S - - - Aldo/keto reductase family
DMHIIBIA_00226 6.05e-135 yxaC - - M - - - effector of murein hydrolase
DMHIIBIA_00227 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
DMHIIBIA_00228 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_00229 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_00230 1.83e-116 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
DMHIIBIA_00231 6.17e-133 - - - T - - - Histidine kinase
DMHIIBIA_00232 8.72e-105 - - - KT - - - helix_turn_helix, Lux Regulon
DMHIIBIA_00233 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00234 2.48e-183 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
DMHIIBIA_00235 4.49e-155 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
DMHIIBIA_00236 1.62e-19 - - - - - - - -
DMHIIBIA_00237 1.13e-72 - - - Q - - - Thioesterase domain
DMHIIBIA_00238 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
DMHIIBIA_00239 1.26e-148 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
DMHIIBIA_00240 0.0 - - - Q ko:K13614 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
DMHIIBIA_00241 0.0 - - - Q - - - Polyketide synthase modules and related proteins
DMHIIBIA_00242 7.24e-121 - - - Q - - - Flavin containing amine oxidoreductase
DMHIIBIA_00243 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
DMHIIBIA_00244 2.35e-50 - - - Q - - - Dimerisation domain
DMHIIBIA_00245 1.05e-102 - - - S - - - Domain of unknown function (DUF4879)
DMHIIBIA_00246 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
DMHIIBIA_00247 6.17e-145 yqeB - - - - - - -
DMHIIBIA_00248 7.84e-55 ybyB - - - - - - -
DMHIIBIA_00249 0.0 ybeC - - E - - - amino acid
DMHIIBIA_00250 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
DMHIIBIA_00251 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
DMHIIBIA_00252 4.08e-23 - - - S - - - Protein of unknown function (DUF2651)
DMHIIBIA_00253 2.35e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
DMHIIBIA_00255 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
DMHIIBIA_00256 1.05e-46 - - - - - - - -
DMHIIBIA_00257 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
DMHIIBIA_00258 1.54e-248 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
DMHIIBIA_00259 6.53e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DMHIIBIA_00260 3.15e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMHIIBIA_00261 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
DMHIIBIA_00262 1.45e-192 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
DMHIIBIA_00263 2.49e-54 ybfN - - - - - - -
DMHIIBIA_00264 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
DMHIIBIA_00265 5.79e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DMHIIBIA_00266 5.86e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
DMHIIBIA_00267 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DMHIIBIA_00268 5.89e-230 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
DMHIIBIA_00269 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
DMHIIBIA_00270 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
DMHIIBIA_00271 1.05e-270 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_00272 5.57e-219 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
DMHIIBIA_00273 2.79e-157 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
DMHIIBIA_00274 2.81e-34 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
DMHIIBIA_00275 1.23e-197 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMHIIBIA_00276 9.1e-141 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
DMHIIBIA_00277 3.56e-234 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DMHIIBIA_00278 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
DMHIIBIA_00279 2.19e-73 ydfQ - - CO - - - Thioredoxin
DMHIIBIA_00280 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
DMHIIBIA_00281 1.75e-100 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
DMHIIBIA_00282 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
DMHIIBIA_00283 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DMHIIBIA_00284 4.55e-156 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMHIIBIA_00285 9.45e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DMHIIBIA_00286 1.06e-260 ycbU - - E - - - Selenocysteine lyase
DMHIIBIA_00287 1.44e-312 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
DMHIIBIA_00288 1.48e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
DMHIIBIA_00289 2.85e-247 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DMHIIBIA_00290 8.07e-148 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
DMHIIBIA_00291 1.61e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
DMHIIBIA_00292 3.62e-217 yccK - - C - - - Aldo keto reductase
DMHIIBIA_00293 2.66e-225 ycdA - - S - - - Domain of unknown function (DUF5105)
DMHIIBIA_00294 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00295 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00296 5.77e-118 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
DMHIIBIA_00297 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
DMHIIBIA_00298 4.28e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
DMHIIBIA_00299 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
DMHIIBIA_00300 8.57e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
DMHIIBIA_00301 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DMHIIBIA_00302 6.86e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DMHIIBIA_00303 3.3e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_00304 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
DMHIIBIA_00305 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
DMHIIBIA_00306 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
DMHIIBIA_00307 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
DMHIIBIA_00308 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
DMHIIBIA_00309 1.17e-246 yceH - - P - - - Belongs to the TelA family
DMHIIBIA_00310 6.09e-275 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
DMHIIBIA_00311 7.71e-294 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
DMHIIBIA_00312 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
DMHIIBIA_00313 8.18e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
DMHIIBIA_00314 1.04e-266 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
DMHIIBIA_00315 1.48e-289 ycgA - - S - - - Membrane
DMHIIBIA_00316 2.55e-105 ycgB - - - - - - -
DMHIIBIA_00317 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
DMHIIBIA_00318 1.09e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
DMHIIBIA_00319 0.0 mdr - - EGP - - - the major facilitator superfamily
DMHIIBIA_00320 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_00321 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
DMHIIBIA_00322 2.52e-193 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
DMHIIBIA_00323 3.84e-313 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_00324 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
DMHIIBIA_00325 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DMHIIBIA_00326 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
DMHIIBIA_00327 2.74e-140 tmrB - - S - - - AAA domain
DMHIIBIA_00328 2.22e-187 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
DMHIIBIA_00329 1.66e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_00330 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMHIIBIA_00331 1.63e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
DMHIIBIA_00332 4.33e-189 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
DMHIIBIA_00333 3.91e-216 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
DMHIIBIA_00334 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
DMHIIBIA_00335 7.72e-312 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMHIIBIA_00336 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
DMHIIBIA_00337 2.35e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
DMHIIBIA_00338 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
DMHIIBIA_00339 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
DMHIIBIA_00340 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMHIIBIA_00341 3.91e-287 yciC - - S - - - GTPases (G3E family)
DMHIIBIA_00342 2.14e-282 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DMHIIBIA_00343 2.29e-95 yckC - - S - - - membrane
DMHIIBIA_00344 1.46e-64 - - - S - - - Protein of unknown function (DUF2680)
DMHIIBIA_00345 1.27e-86 nin - - S - - - Competence protein J (ComJ)
DMHIIBIA_00346 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
DMHIIBIA_00347 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
DMHIIBIA_00348 8.64e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
DMHIIBIA_00349 1.38e-82 hxlR - - K - - - transcriptional
DMHIIBIA_00350 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_00351 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_00352 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_00353 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_00354 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
DMHIIBIA_00355 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
DMHIIBIA_00356 2.48e-315 - - - E - - - Aminotransferase class I and II
DMHIIBIA_00357 3.72e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
DMHIIBIA_00358 9.99e-141 yczE - - S ko:K07149 - ko00000 membrane
DMHIIBIA_00359 2.28e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DMHIIBIA_00360 4.99e-154 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DMHIIBIA_00361 1.62e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
DMHIIBIA_00362 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
DMHIIBIA_00363 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DMHIIBIA_00364 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
DMHIIBIA_00365 4.71e-51 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
DMHIIBIA_00366 1.67e-100 yclD - - - - - - -
DMHIIBIA_00367 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
DMHIIBIA_00368 0.0 yclG - - M - - - Pectate lyase superfamily protein
DMHIIBIA_00370 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
DMHIIBIA_00371 2.31e-299 gerKC - - S ko:K06297 - ko00000 spore germination
DMHIIBIA_00372 6.5e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
DMHIIBIA_00373 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_00374 3.64e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMHIIBIA_00375 7.09e-180 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DMHIIBIA_00376 2.11e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DMHIIBIA_00377 5.6e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00378 1.97e-276 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
DMHIIBIA_00379 3.71e-316 yxeQ - - S - - - MmgE/PrpD family
DMHIIBIA_00380 3.66e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
DMHIIBIA_00381 4.76e-307 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
DMHIIBIA_00382 1.06e-163 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_00383 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
DMHIIBIA_00384 6.79e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DMHIIBIA_00386 4.58e-316 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DMHIIBIA_00387 1.1e-210 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_00388 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_00389 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00390 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
DMHIIBIA_00391 2.58e-311 ycnB - - EGP - - - the major facilitator superfamily
DMHIIBIA_00392 3.51e-194 ycnC - - K - - - Transcriptional regulator
DMHIIBIA_00393 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
DMHIIBIA_00394 1.97e-59 ycnE - - S - - - Monooxygenase
DMHIIBIA_00395 3.92e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DMHIIBIA_00396 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DMHIIBIA_00397 1.4e-283 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMHIIBIA_00398 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DMHIIBIA_00399 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
DMHIIBIA_00400 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_00401 3.4e-130 ycnI - - S - - - protein conserved in bacteria
DMHIIBIA_00402 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
DMHIIBIA_00403 1.74e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DMHIIBIA_00404 9.6e-73 - - - - - - - -
DMHIIBIA_00405 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
DMHIIBIA_00406 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
DMHIIBIA_00407 1.06e-259 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
DMHIIBIA_00408 2.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
DMHIIBIA_00410 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
DMHIIBIA_00411 1.18e-178 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
DMHIIBIA_00412 7.29e-269 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
DMHIIBIA_00413 4.01e-191 ycsI - - S - - - Belongs to the D-glutamate cyclase family
DMHIIBIA_00414 6.36e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
DMHIIBIA_00415 4.91e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
DMHIIBIA_00416 4.65e-167 kipR - - K - - - Transcriptional regulator
DMHIIBIA_00417 1.11e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
DMHIIBIA_00419 5.95e-75 yczJ - - S - - - biosynthesis
DMHIIBIA_00420 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
DMHIIBIA_00421 6.05e-220 ycsN - - S - - - Oxidoreductase
DMHIIBIA_00422 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
DMHIIBIA_00423 0.0 ydaB - - IQ - - - acyl-CoA ligase
DMHIIBIA_00424 5.2e-205 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_00425 4.57e-124 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
DMHIIBIA_00426 4.04e-149 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DMHIIBIA_00427 1.83e-101 ydaG - - S - - - general stress protein
DMHIIBIA_00428 7.59e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
DMHIIBIA_00429 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
DMHIIBIA_00430 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
DMHIIBIA_00431 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMHIIBIA_00432 6.35e-255 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
DMHIIBIA_00433 2.19e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
DMHIIBIA_00434 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
DMHIIBIA_00435 2.63e-302 ydaM - - M - - - Glycosyl transferase family group 2
DMHIIBIA_00436 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
DMHIIBIA_00437 0.0 ydaO - - E - - - amino acid
DMHIIBIA_00438 6.71e-92 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
DMHIIBIA_00439 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
DMHIIBIA_00440 2.21e-18 - - - - - - - -
DMHIIBIA_00442 1.78e-114 - - - - - - - -
DMHIIBIA_00443 3.33e-127 - - - - - - - -
DMHIIBIA_00444 7.18e-52 - - - - - - - -
DMHIIBIA_00445 5.35e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
DMHIIBIA_00447 1.95e-45 ydaT - - - - - - -
DMHIIBIA_00448 5.53e-96 yvaD - - S - - - Family of unknown function (DUF5360)
DMHIIBIA_00449 1.66e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
DMHIIBIA_00450 2.19e-181 ydbA - - P - - - EcsC protein family
DMHIIBIA_00451 1.24e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
DMHIIBIA_00452 2.65e-78 ydbB - - G - - - Cupin domain
DMHIIBIA_00453 2.39e-78 ydbC - - S - - - Domain of unknown function (DUF4937
DMHIIBIA_00454 7.8e-198 ydbD - - P ko:K07217 - ko00000 Catalase
DMHIIBIA_00455 3.82e-255 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
DMHIIBIA_00456 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DMHIIBIA_00457 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
DMHIIBIA_00458 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DMHIIBIA_00459 2.88e-229 ydbI - - S - - - AI-2E family transporter
DMHIIBIA_00460 9.27e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00461 9.93e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DMHIIBIA_00462 1.32e-69 ydbL - - - - - - -
DMHIIBIA_00463 3.63e-261 ydbM - - I - - - acyl-CoA dehydrogenase
DMHIIBIA_00464 1.13e-15 - - - S - - - Fur-regulated basic protein B
DMHIIBIA_00465 6.58e-14 - - - S - - - Fur-regulated basic protein A
DMHIIBIA_00466 1.91e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMHIIBIA_00467 2.25e-74 ydbP - - CO - - - Thioredoxin
DMHIIBIA_00468 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
DMHIIBIA_00469 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DMHIIBIA_00470 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DMHIIBIA_00471 5.73e-92 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
DMHIIBIA_00472 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
DMHIIBIA_00473 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
DMHIIBIA_00474 4.42e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DMHIIBIA_00475 6.39e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
DMHIIBIA_00476 5.68e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMHIIBIA_00477 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
DMHIIBIA_00478 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
DMHIIBIA_00479 6.07e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
DMHIIBIA_00480 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
DMHIIBIA_00481 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
DMHIIBIA_00482 8.83e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
DMHIIBIA_00483 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
DMHIIBIA_00484 5.84e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
DMHIIBIA_00485 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_00486 2.74e-139 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
DMHIIBIA_00487 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
DMHIIBIA_00488 1.78e-21 - - - - - - - -
DMHIIBIA_00489 1.74e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
DMHIIBIA_00497 7.8e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
DMHIIBIA_00498 2.8e-191 - - - S - - - Serine aminopeptidase, S33
DMHIIBIA_00499 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
DMHIIBIA_00500 5.25e-174 - - - I ko:K01066 - ko00000,ko01000 esterase
DMHIIBIA_00501 2.9e-61 ohrB - - O - - - OsmC-like protein
DMHIIBIA_00502 3.16e-64 ohrR - - K - - - Transcriptional regulator
DMHIIBIA_00503 3.75e-93 ywnA - - K - - - Transcriptional regulator
DMHIIBIA_00504 4.3e-142 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
DMHIIBIA_00505 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
DMHIIBIA_00506 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
DMHIIBIA_00507 2.63e-53 yrkD - - S - - - protein conserved in bacteria
DMHIIBIA_00508 1.38e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
DMHIIBIA_00509 9.11e-24 - - - P - - - Rhodanese Homology Domain
DMHIIBIA_00510 4.42e-130 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
DMHIIBIA_00511 2.03e-254 yrkH - - P - - - Rhodanese Homology Domain
DMHIIBIA_00512 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
DMHIIBIA_00513 1.2e-164 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
DMHIIBIA_00514 7.67e-152 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
DMHIIBIA_00515 8.25e-131 - - - S - - - Protein of unknown function (DUF2812)
DMHIIBIA_00516 7.89e-66 - - - K - - - Transcriptional regulator PadR-like family
DMHIIBIA_00517 1.76e-232 - - - S - - - Patatin-like phospholipase
DMHIIBIA_00518 1.18e-108 - - - S - - - DinB superfamily
DMHIIBIA_00519 8.43e-142 dpaL 4.3.1.15 - E ko:K01751 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
DMHIIBIA_00520 4.64e-86 - - - K - - - COG1802 Transcriptional regulators
DMHIIBIA_00521 4.46e-52 - - - J - - - Endoribonuclease L-PSP
DMHIIBIA_00522 8.01e-177 - - - E ko:K03837 - ko00000,ko02000 Serine transporter
DMHIIBIA_00523 3.52e-205 - - - E - - - Peptidase dimerisation domain
DMHIIBIA_00524 5.7e-161 - - - K - - - helix_turn_helix, arabinose operon control protein
DMHIIBIA_00525 3.83e-219 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
DMHIIBIA_00526 1.01e-295 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DMHIIBIA_00527 3.08e-242 ydeG - - EGP - - - Major facilitator superfamily
DMHIIBIA_00528 6.45e-38 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
DMHIIBIA_00531 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
DMHIIBIA_00532 9.72e-14 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_00533 6.49e-217 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
DMHIIBIA_00534 1.08e-247 trkA - - P ko:K07222 - ko00000 Oxidoreductase
DMHIIBIA_00537 1.3e-08 ykkA - - S - - - Protein of unknown function (DUF664)
DMHIIBIA_00538 2.36e-190 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
DMHIIBIA_00540 1.09e-249 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
DMHIIBIA_00541 2.4e-68 ydeH - - - - - - -
DMHIIBIA_00542 3.42e-211 - - - S - - - Sodium Bile acid symporter family
DMHIIBIA_00543 5.02e-255 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
DMHIIBIA_00544 1.21e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
DMHIIBIA_00545 4.37e-285 nhaC_1 - - C - - - antiporter
DMHIIBIA_00546 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
DMHIIBIA_00547 1.71e-145 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_00549 1.19e-247 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
DMHIIBIA_00550 1.35e-129 ydeS - - K - - - Transcriptional regulator
DMHIIBIA_00551 3.45e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
DMHIIBIA_00552 2.4e-33 yraE - - - ko:K06440 - ko00000 -
DMHIIBIA_00553 3.41e-279 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DMHIIBIA_00554 4.76e-84 yraF - - M - - - Spore coat protein
DMHIIBIA_00555 9.9e-49 yraG - - - ko:K06440 - ko00000 -
DMHIIBIA_00556 1.16e-273 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_00557 3.82e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_00558 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
DMHIIBIA_00559 3.98e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
DMHIIBIA_00560 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
DMHIIBIA_00561 5.07e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
DMHIIBIA_00562 6.07e-192 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_00563 3.98e-250 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
DMHIIBIA_00564 9.58e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
DMHIIBIA_00565 3.22e-287 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DMHIIBIA_00566 1.06e-198 - - - K - - - Helix-turn-helix XRE-family like proteins
DMHIIBIA_00567 2.47e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
DMHIIBIA_00568 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
DMHIIBIA_00569 2.4e-192 bltR - - K - - - helix_turn_helix, mercury resistance
DMHIIBIA_00570 1.04e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DMHIIBIA_00571 3.06e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
DMHIIBIA_00572 9.06e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
DMHIIBIA_00573 1.77e-211 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
DMHIIBIA_00574 7.66e-153 ydhC - - K - - - FCD
DMHIIBIA_00575 7.59e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DMHIIBIA_00578 0.0 pbpE - - V - - - Beta-lactamase
DMHIIBIA_00580 6.11e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
DMHIIBIA_00581 2.24e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
DMHIIBIA_00582 2.4e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
DMHIIBIA_00583 1.09e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
DMHIIBIA_00584 2.04e-275 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
DMHIIBIA_00585 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
DMHIIBIA_00586 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DMHIIBIA_00587 4.95e-134 yvdT_1 - - K - - - Transcriptional regulator
DMHIIBIA_00588 0.0 ybeC - - E - - - amino acid
DMHIIBIA_00589 9.97e-211 ydhU - - P ko:K07217 - ko00000 Catalase
DMHIIBIA_00590 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
DMHIIBIA_00591 3.16e-234 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
DMHIIBIA_00592 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMHIIBIA_00595 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00598 4.87e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DMHIIBIA_00599 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
DMHIIBIA_00600 2.3e-159 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
DMHIIBIA_00601 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DMHIIBIA_00602 1.03e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMHIIBIA_00603 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
DMHIIBIA_00604 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
DMHIIBIA_00605 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DMHIIBIA_00606 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DMHIIBIA_00607 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMHIIBIA_00608 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
DMHIIBIA_00609 1.67e-164 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
DMHIIBIA_00610 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMHIIBIA_00611 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DMHIIBIA_00612 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
DMHIIBIA_00613 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
DMHIIBIA_00614 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
DMHIIBIA_00615 3.45e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
DMHIIBIA_00616 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
DMHIIBIA_00617 4.9e-39 yjdJ - - S - - - Domain of unknown function (DUF4306)
DMHIIBIA_00618 3.2e-145 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
DMHIIBIA_00619 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMHIIBIA_00620 3.05e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
DMHIIBIA_00621 6.89e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
DMHIIBIA_00622 0.0 oatA - - I - - - Acyltransferase family
DMHIIBIA_00623 1.38e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
DMHIIBIA_00624 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00625 8.25e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
DMHIIBIA_00626 6.51e-82 ydjM - - M - - - Lytic transglycolase
DMHIIBIA_00627 6.75e-193 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
DMHIIBIA_00629 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
DMHIIBIA_00630 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
DMHIIBIA_00631 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_00632 8.93e-223 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
DMHIIBIA_00633 5.07e-265 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
DMHIIBIA_00634 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
DMHIIBIA_00635 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
DMHIIBIA_00636 4.67e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00637 8.68e-317 - - - S - - - Domain of unknown function (DUF4179)
DMHIIBIA_00638 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
DMHIIBIA_00639 6.19e-168 yebC - - M - - - Membrane
DMHIIBIA_00641 1.21e-118 yebE - - S - - - UPF0316 protein
DMHIIBIA_00642 6.56e-40 yebG - - S - - - NETI protein
DMHIIBIA_00643 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DMHIIBIA_00644 1.07e-285 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DMHIIBIA_00645 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMHIIBIA_00646 3.96e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
DMHIIBIA_00647 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMHIIBIA_00648 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMHIIBIA_00649 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMHIIBIA_00650 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DMHIIBIA_00651 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
DMHIIBIA_00652 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMHIIBIA_00653 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
DMHIIBIA_00654 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
DMHIIBIA_00655 1.2e-33 - - - S - - - Protein of unknown function (DUF2892)
DMHIIBIA_00656 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
DMHIIBIA_00657 6.02e-247 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
DMHIIBIA_00658 2.03e-67 yerC - - S - - - protein conserved in bacteria
DMHIIBIA_00659 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
DMHIIBIA_00660 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DMHIIBIA_00661 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
DMHIIBIA_00662 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMHIIBIA_00663 6.46e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
DMHIIBIA_00664 3.34e-244 yerI - - S - - - homoserine kinase type II (protein kinase fold)
DMHIIBIA_00665 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
DMHIIBIA_00666 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMHIIBIA_00667 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMHIIBIA_00668 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DMHIIBIA_00669 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMHIIBIA_00670 4.13e-193 yerO - - K - - - Transcriptional regulator
DMHIIBIA_00671 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMHIIBIA_00672 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DMHIIBIA_00673 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMHIIBIA_00674 5.4e-28 - - - - - - - -
DMHIIBIA_00675 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
DMHIIBIA_00676 3.36e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
DMHIIBIA_00677 1.84e-49 - - - S - - - Protein of unknown function, DUF600
DMHIIBIA_00678 1.27e-109 - - - S - - - Protein of unknown function, DUF600
DMHIIBIA_00679 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
DMHIIBIA_00680 2.73e-27 - - - - - - - -
DMHIIBIA_00681 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
DMHIIBIA_00683 1.32e-136 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
DMHIIBIA_00684 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
DMHIIBIA_00685 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
DMHIIBIA_00686 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
DMHIIBIA_00687 6.63e-122 yesJ - - K - - - Acetyltransferase (GNAT) family
DMHIIBIA_00688 0.000118 - - - - - - - -
DMHIIBIA_00689 2.12e-155 yetF - - S - - - membrane
DMHIIBIA_00690 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
DMHIIBIA_00691 8.92e-84 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_00692 3.63e-196 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DMHIIBIA_00693 5.48e-31 - - - S - - - Uncharacterized small protein (DUF2292)
DMHIIBIA_00694 2.13e-72 - - - H - - - riboflavin kinase activity
DMHIIBIA_00695 3.11e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
DMHIIBIA_00697 1.92e-113 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_00698 8.76e-258 yetM - - CH - - - FAD binding domain
DMHIIBIA_00699 2.38e-252 yetN - - S - - - Protein of unknown function (DUF3900)
DMHIIBIA_00700 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
DMHIIBIA_00701 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
DMHIIBIA_00702 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
DMHIIBIA_00703 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
DMHIIBIA_00704 7.72e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
DMHIIBIA_00705 2.22e-279 yfnE - - S - - - Glycosyltransferase like family 2
DMHIIBIA_00706 2.33e-237 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
DMHIIBIA_00707 6.35e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_00708 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
DMHIIBIA_00709 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DMHIIBIA_00710 2.04e-162 yfmS - - NT - - - chemotaxis protein
DMHIIBIA_00711 3.48e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DMHIIBIA_00712 3.45e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
DMHIIBIA_00713 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DMHIIBIA_00714 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
DMHIIBIA_00715 2.81e-261 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
DMHIIBIA_00716 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DMHIIBIA_00717 2.32e-260 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
DMHIIBIA_00718 1.86e-55 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
DMHIIBIA_00719 5.49e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
DMHIIBIA_00720 2.1e-31 - - - S - - - Protein of unknown function (DUF3212)
DMHIIBIA_00721 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
DMHIIBIA_00722 1.87e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
DMHIIBIA_00723 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
DMHIIBIA_00725 2.5e-47 - - - Q - - - Collagen triple helix repeat (20 copies)
DMHIIBIA_00729 2.31e-08 - - - S - - - domain, Protein
DMHIIBIA_00731 0.0 ywpD - - T - - - Histidine kinase
DMHIIBIA_00732 2.37e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
DMHIIBIA_00733 0.0 - - - M - - - cell wall anchor domain
DMHIIBIA_00734 2.25e-103 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
DMHIIBIA_00735 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DMHIIBIA_00736 9.33e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
DMHIIBIA_00737 5.39e-224 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
DMHIIBIA_00738 5.52e-285 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
DMHIIBIA_00739 1.34e-189 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DMHIIBIA_00740 3.37e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DMHIIBIA_00741 3.93e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
DMHIIBIA_00742 1.7e-156 yflK - - S - - - protein conserved in bacteria
DMHIIBIA_00743 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
DMHIIBIA_00744 1.98e-26 yflI - - - - - - -
DMHIIBIA_00745 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
DMHIIBIA_00746 1.9e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
DMHIIBIA_00747 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
DMHIIBIA_00748 1.17e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
DMHIIBIA_00749 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
DMHIIBIA_00750 4.9e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
DMHIIBIA_00751 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DMHIIBIA_00752 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
DMHIIBIA_00753 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
DMHIIBIA_00754 4.49e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_00755 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
DMHIIBIA_00756 3.14e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
DMHIIBIA_00757 1.45e-158 frp - - C - - - nitroreductase
DMHIIBIA_00758 2.34e-164 yibF - - S - - - YibE/F-like protein
DMHIIBIA_00759 3e-253 yibE - - S - - - YibE/F-like protein
DMHIIBIA_00760 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
DMHIIBIA_00761 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
DMHIIBIA_00762 2.15e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
DMHIIBIA_00763 2.02e-215 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMHIIBIA_00764 2.04e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DMHIIBIA_00765 3.85e-249 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_00766 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
DMHIIBIA_00767 6.88e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMHIIBIA_00768 1.51e-69 yfkI - - S - - - gas vesicle protein
DMHIIBIA_00769 1.6e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
DMHIIBIA_00770 6.71e-12 - - - - - - - -
DMHIIBIA_00771 5.89e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_00772 1.7e-238 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
DMHIIBIA_00773 1.33e-184 yfkD - - S - - - YfkD-like protein
DMHIIBIA_00774 4.1e-186 yfkC - - M - - - Mechanosensitive ion channel
DMHIIBIA_00775 4.65e-279 yfkA - - S - - - YfkB-like domain
DMHIIBIA_00776 7.99e-37 yfjT - - - - - - -
DMHIIBIA_00777 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
DMHIIBIA_00778 4.94e-187 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
DMHIIBIA_00780 2.61e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
DMHIIBIA_00781 1.21e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DMHIIBIA_00782 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMHIIBIA_00783 1.27e-58 - - - S - - - YfzA-like protein
DMHIIBIA_00784 4.22e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMHIIBIA_00785 1.76e-112 yfjM - - S - - - Psort location Cytoplasmic, score
DMHIIBIA_00786 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DMHIIBIA_00787 5.1e-240 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DMHIIBIA_00788 1.88e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DMHIIBIA_00789 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DMHIIBIA_00790 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
DMHIIBIA_00791 5.47e-21 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
DMHIIBIA_00792 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DMHIIBIA_00793 4.47e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
DMHIIBIA_00794 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_00795 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
DMHIIBIA_00796 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DMHIIBIA_00797 7.86e-82 yfiD3 - - S - - - DoxX
DMHIIBIA_00798 3.19e-203 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
DMHIIBIA_00799 7.77e-210 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DMHIIBIA_00800 9.33e-125 padR - - K - - - transcriptional
DMHIIBIA_00801 3.47e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
DMHIIBIA_00802 1.48e-233 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DMHIIBIA_00803 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
DMHIIBIA_00804 1.66e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
DMHIIBIA_00805 1.05e-124 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
DMHIIBIA_00806 0.0 yfiU - - EGP - - - the major facilitator superfamily
DMHIIBIA_00807 2.29e-107 yfiV - - K - - - transcriptional
DMHIIBIA_00808 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DMHIIBIA_00809 1.11e-203 yfhB - - S - - - PhzF family
DMHIIBIA_00810 4.76e-137 yfhC - - C - - - nitroreductase
DMHIIBIA_00811 3.61e-34 yfhD - - S - - - YfhD-like protein
DMHIIBIA_00813 1.65e-212 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
DMHIIBIA_00814 5.21e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
DMHIIBIA_00815 3.1e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
DMHIIBIA_00816 2.25e-265 yfhI - - EGP - - - -transporter
DMHIIBIA_00818 1.66e-214 mpr - - M - - - Belongs to the peptidase S1B family
DMHIIBIA_00819 2.57e-59 yfhJ - - S - - - WVELL protein
DMHIIBIA_00820 5.47e-120 yfhK - - T - - - Bacterial SH3 domain homologues
DMHIIBIA_00821 9.59e-54 yfhL - - S - - - SdpI/YhfL protein family
DMHIIBIA_00822 1.95e-218 - - - S - - - Alpha/beta hydrolase family
DMHIIBIA_00823 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DMHIIBIA_00824 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
DMHIIBIA_00825 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
DMHIIBIA_00826 1.64e-261 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
DMHIIBIA_00827 1.47e-49 yfhS - - - - - - -
DMHIIBIA_00828 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_00829 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
DMHIIBIA_00830 1.4e-49 ygaB - - S - - - YgaB-like protein
DMHIIBIA_00831 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
DMHIIBIA_00832 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
DMHIIBIA_00833 5.27e-239 ygaE - - S - - - Membrane
DMHIIBIA_00834 3.97e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
DMHIIBIA_00835 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
DMHIIBIA_00836 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
DMHIIBIA_00837 4.67e-75 ygzB - - S - - - UPF0295 protein
DMHIIBIA_00838 1.59e-212 ygxA - - S - - - Nucleotidyltransferase-like
DMHIIBIA_00839 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_00858 1.91e-24 - - - C - - - Na+/H+ antiporter family
DMHIIBIA_00859 5.48e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
DMHIIBIA_00860 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMHIIBIA_00861 0.0 ygaK - - C - - - Berberine and berberine like
DMHIIBIA_00863 5.46e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
DMHIIBIA_00864 4.91e-187 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DMHIIBIA_00865 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_00866 3.84e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_00867 1.9e-167 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_00868 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DMHIIBIA_00869 8.69e-230 - - - S ko:K07045 - ko00000 Amidohydrolase
DMHIIBIA_00870 1.5e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
DMHIIBIA_00871 2.09e-221 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
DMHIIBIA_00872 9.64e-185 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
DMHIIBIA_00873 8.61e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
DMHIIBIA_00874 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMHIIBIA_00875 9.07e-107 ygaO - - - - - - -
DMHIIBIA_00876 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_00878 1.9e-138 yhzB - - S - - - B3/4 domain
DMHIIBIA_00879 6.66e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMHIIBIA_00880 9.5e-222 yhbB - - S - - - Putative amidase domain
DMHIIBIA_00881 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DMHIIBIA_00882 1.62e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
DMHIIBIA_00883 8.03e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
DMHIIBIA_00884 1.91e-92 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
DMHIIBIA_00885 1.23e-07 - - - - - - - -
DMHIIBIA_00886 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
DMHIIBIA_00887 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
DMHIIBIA_00888 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
DMHIIBIA_00889 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
DMHIIBIA_00890 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
DMHIIBIA_00891 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
DMHIIBIA_00892 1.41e-72 yhcC - - - - - - -
DMHIIBIA_00893 2.33e-66 - - - - - - - -
DMHIIBIA_00894 1.35e-80 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_00895 5.71e-159 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00896 7.87e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00897 1.29e-208 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DMHIIBIA_00898 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
DMHIIBIA_00899 2.56e-184 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
DMHIIBIA_00900 1.43e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
DMHIIBIA_00901 7.04e-306 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DMHIIBIA_00902 1.07e-74 yhcM - - - - - - -
DMHIIBIA_00903 3.14e-121 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DMHIIBIA_00904 3.95e-205 yhcP - - - - - - -
DMHIIBIA_00905 7.38e-150 yhcQ - - M - - - Spore coat protein
DMHIIBIA_00906 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
DMHIIBIA_00907 2.63e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
DMHIIBIA_00908 3.09e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
DMHIIBIA_00909 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
DMHIIBIA_00910 3.54e-90 yhcV - - S - - - COG0517 FOG CBS domain
DMHIIBIA_00911 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
DMHIIBIA_00912 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DMHIIBIA_00913 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMHIIBIA_00914 8.57e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DMHIIBIA_00915 2.32e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
DMHIIBIA_00916 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMHIIBIA_00917 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DMHIIBIA_00918 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
DMHIIBIA_00919 6.31e-255 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_00920 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_00921 9.77e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
DMHIIBIA_00922 6.98e-53 yhdB - - S - - - YhdB-like protein
DMHIIBIA_00923 1.46e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
DMHIIBIA_00924 4.93e-296 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DMHIIBIA_00925 7.66e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
DMHIIBIA_00926 0.0 ygxB - - M - - - Conserved TM helix
DMHIIBIA_00927 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
DMHIIBIA_00928 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
DMHIIBIA_00929 2.8e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DMHIIBIA_00930 1.16e-208 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_00931 6.67e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DMHIIBIA_00932 7.51e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_00933 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
DMHIIBIA_00934 4.85e-266 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DMHIIBIA_00935 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
DMHIIBIA_00936 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
DMHIIBIA_00937 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_00938 8.84e-140 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DMHIIBIA_00939 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DMHIIBIA_00940 1.97e-92 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
DMHIIBIA_00941 2.01e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
DMHIIBIA_00942 1.84e-299 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DMHIIBIA_00943 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
DMHIIBIA_00944 2.48e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMHIIBIA_00945 1.58e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMHIIBIA_00946 3.52e-163 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
DMHIIBIA_00947 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
DMHIIBIA_00948 1.91e-261 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
DMHIIBIA_00949 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DMHIIBIA_00950 4.69e-199 nodB1 - - G - - - deacetylase
DMHIIBIA_00951 1.39e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
DMHIIBIA_00952 1e-113 pksA - - K - - - Transcriptional regulator
DMHIIBIA_00953 1.55e-123 ymcC - - S - - - Membrane
DMHIIBIA_00954 7.15e-110 - - - T - - - universal stress protein
DMHIIBIA_00956 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DMHIIBIA_00957 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DMHIIBIA_00958 6.68e-143 yheG - - GM - - - NAD(P)H-binding
DMHIIBIA_00960 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
DMHIIBIA_00961 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
DMHIIBIA_00962 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
DMHIIBIA_00963 4.41e-272 yheC - - HJ - - - YheC/D like ATP-grasp
DMHIIBIA_00964 3.19e-263 yheB - - S - - - Belongs to the UPF0754 family
DMHIIBIA_00965 3.3e-70 yheA - - S - - - Belongs to the UPF0342 family
DMHIIBIA_00966 9.66e-256 yhaZ - - L - - - DNA alkylation repair enzyme
DMHIIBIA_00967 9.87e-204 yhaX - - S - - - haloacid dehalogenase-like hydrolase
DMHIIBIA_00968 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
DMHIIBIA_00969 4.62e-315 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
DMHIIBIA_00970 3.31e-265 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
DMHIIBIA_00971 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
DMHIIBIA_00973 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
DMHIIBIA_00974 7.01e-20 - - - S - - - YhzD-like protein
DMHIIBIA_00975 5.34e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_00976 2.05e-278 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
DMHIIBIA_00977 1.02e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
DMHIIBIA_00978 0.0 yhaN - - L - - - AAA domain
DMHIIBIA_00979 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
DMHIIBIA_00980 5.79e-43 yhaL - - S - - - Sporulation protein YhaL
DMHIIBIA_00981 1.53e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DMHIIBIA_00982 1.29e-123 yhaK - - S - - - Putative zincin peptidase
DMHIIBIA_00983 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
DMHIIBIA_00984 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
DMHIIBIA_00985 4.74e-55 yhaH - - S - - - YtxH-like protein
DMHIIBIA_00986 2.55e-24 - - - - - - - -
DMHIIBIA_00987 8.25e-100 trpP - - S - - - Tryptophan transporter TrpP
DMHIIBIA_00988 6.9e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DMHIIBIA_00989 8.27e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DMHIIBIA_00990 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
DMHIIBIA_00991 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
DMHIIBIA_00992 3.38e-159 ecsC - - S - - - EcsC protein family
DMHIIBIA_00993 2.33e-281 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DMHIIBIA_00994 1.39e-311 yhfA - - C - - - membrane
DMHIIBIA_00995 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
DMHIIBIA_00996 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DMHIIBIA_00997 2.99e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DMHIIBIA_00998 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
DMHIIBIA_00999 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DMHIIBIA_01000 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01001 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
DMHIIBIA_01002 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMHIIBIA_01004 8.97e-252 yhfE - - G - - - peptidase M42
DMHIIBIA_01005 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DMHIIBIA_01007 8.09e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
DMHIIBIA_01008 1.85e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
DMHIIBIA_01009 1.67e-138 yhfK - - GM - - - NmrA-like family
DMHIIBIA_01010 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
DMHIIBIA_01011 6.81e-86 yhfM - - - - - - -
DMHIIBIA_01012 1.24e-298 yhfN - - O - - - Peptidase M48
DMHIIBIA_01013 2.61e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DMHIIBIA_01014 2.45e-190 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
DMHIIBIA_01015 1.73e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
DMHIIBIA_01016 2.48e-253 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
DMHIIBIA_01017 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
DMHIIBIA_01018 2.17e-115 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
DMHIIBIA_01019 3.24e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
DMHIIBIA_01020 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
DMHIIBIA_01021 1.11e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_01022 3.87e-42 yhzC - - S - - - IDEAL
DMHIIBIA_01023 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
DMHIIBIA_01024 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
DMHIIBIA_01025 1.16e-80 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
DMHIIBIA_01026 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
DMHIIBIA_01027 1.74e-57 yhjA - - S - - - Excalibur calcium-binding domain
DMHIIBIA_01028 2.64e-63 - - - S - - - Belongs to the UPF0145 family
DMHIIBIA_01029 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMHIIBIA_01030 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
DMHIIBIA_01031 1.68e-78 yhjD - - - - - - -
DMHIIBIA_01032 3.17e-142 yhjE - - S - - - SNARE associated Golgi protein
DMHIIBIA_01033 6.7e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DMHIIBIA_01035 0.0 yhjG - - CH - - - FAD binding domain
DMHIIBIA_01036 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_01037 1.15e-260 yhjN - - S ko:K07120 - ko00000 membrane
DMHIIBIA_01038 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_01039 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
DMHIIBIA_01040 1.47e-121 yhjR - - S - - - Rubrerythrin
DMHIIBIA_01041 1.07e-152 ydfS - - S - - - Protein of unknown function (DUF421)
DMHIIBIA_01042 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
DMHIIBIA_01043 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
DMHIIBIA_01044 3.31e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DMHIIBIA_01045 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
DMHIIBIA_01046 2.64e-67 yisB - - V - - - COG1403 Restriction endonuclease
DMHIIBIA_01047 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
DMHIIBIA_01048 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
DMHIIBIA_01049 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
DMHIIBIA_01050 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
DMHIIBIA_01051 3.82e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
DMHIIBIA_01052 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
DMHIIBIA_01053 1.03e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
DMHIIBIA_01054 1.04e-216 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
DMHIIBIA_01055 6.36e-78 yisL - - S - - - UPF0344 protein
DMHIIBIA_01056 1.86e-124 yisN - - S - - - Protein of unknown function (DUF2777)
DMHIIBIA_01057 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
DMHIIBIA_01058 4.09e-166 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
DMHIIBIA_01059 2.14e-312 yisQ - - V - - - Mate efflux family protein
DMHIIBIA_01060 4.72e-206 yisR - - K - - - Transcriptional regulator
DMHIIBIA_01061 4.97e-182 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
DMHIIBIA_01062 9.41e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
DMHIIBIA_01063 3.76e-108 yisT - - S - - - DinB family
DMHIIBIA_01064 2.62e-109 yisX - - S - - - Pentapeptide repeats (9 copies)
DMHIIBIA_01065 1.54e-105 - - - S - - - Acetyltransferase (GNAT) domain
DMHIIBIA_01066 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DMHIIBIA_01067 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
DMHIIBIA_01068 4.36e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
DMHIIBIA_01069 2.44e-218 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
DMHIIBIA_01070 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
DMHIIBIA_01072 5.06e-199 yitS - - S - - - protein conserved in bacteria
DMHIIBIA_01073 6.56e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_01074 6.17e-104 ipi - - S - - - Intracellular proteinase inhibitor
DMHIIBIA_01075 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
DMHIIBIA_01076 1.49e-11 - - - - - - - -
DMHIIBIA_01077 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
DMHIIBIA_01078 4.33e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
DMHIIBIA_01079 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
DMHIIBIA_01080 1.7e-94 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
DMHIIBIA_01081 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
DMHIIBIA_01082 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
DMHIIBIA_01083 7.11e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMHIIBIA_01084 9.99e-288 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMHIIBIA_01085 8.58e-174 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
DMHIIBIA_01086 3.81e-275 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
DMHIIBIA_01087 8.05e-258 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DMHIIBIA_01088 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
DMHIIBIA_01089 1.43e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMHIIBIA_01090 7.21e-39 yjzC - - S - - - YjzC-like protein
DMHIIBIA_01091 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
DMHIIBIA_01092 5.25e-177 yjaU - - I - - - carboxylic ester hydrolase activity
DMHIIBIA_01093 6.81e-134 yjaV - - - - - - -
DMHIIBIA_01094 2.22e-211 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
DMHIIBIA_01095 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
DMHIIBIA_01096 8.09e-44 yjzB - - - - - - -
DMHIIBIA_01097 7.63e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMHIIBIA_01098 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DMHIIBIA_01099 1.84e-190 yjaZ - - O - - - Zn-dependent protease
DMHIIBIA_01100 6.88e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01101 8.8e-239 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01102 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
DMHIIBIA_01103 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01104 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01105 8.77e-188 yjbA - - S - - - Belongs to the UPF0736 family
DMHIIBIA_01106 1.19e-232 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
DMHIIBIA_01107 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DMHIIBIA_01108 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01109 5.09e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01110 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01111 1.22e-217 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01112 2.88e-294 - - - S - - - Putative glycosyl hydrolase domain
DMHIIBIA_01113 4.22e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMHIIBIA_01114 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DMHIIBIA_01115 5.59e-141 yjbE - - P - - - Integral membrane protein TerC family
DMHIIBIA_01116 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DMHIIBIA_01117 5.02e-276 coiA - - S ko:K06198 - ko00000 Competence protein
DMHIIBIA_01118 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
DMHIIBIA_01119 3.14e-27 - - - - - - - -
DMHIIBIA_01120 1.73e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
DMHIIBIA_01121 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
DMHIIBIA_01122 4.96e-149 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DMHIIBIA_01123 1.65e-124 yjbK - - S - - - protein conserved in bacteria
DMHIIBIA_01124 2.03e-80 yjbL - - S - - - Belongs to the UPF0738 family
DMHIIBIA_01125 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
DMHIIBIA_01126 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMHIIBIA_01127 7.01e-213 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
DMHIIBIA_01128 5.06e-182 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
DMHIIBIA_01129 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DMHIIBIA_01130 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DMHIIBIA_01131 3.85e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
DMHIIBIA_01132 4.38e-266 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
DMHIIBIA_01133 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
DMHIIBIA_01134 7.36e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DMHIIBIA_01135 1.02e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DMHIIBIA_01136 3.03e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
DMHIIBIA_01137 7.99e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
DMHIIBIA_01138 9.69e-125 yjbX - - S - - - Spore coat protein
DMHIIBIA_01139 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
DMHIIBIA_01140 2.48e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
DMHIIBIA_01141 2.61e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
DMHIIBIA_01142 8.38e-36 cotW - - - ko:K06341 - ko00000 -
DMHIIBIA_01143 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
DMHIIBIA_01144 8.37e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
DMHIIBIA_01148 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
DMHIIBIA_01149 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
DMHIIBIA_01150 5e-48 - - - - - - - -
DMHIIBIA_01151 1.9e-177 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
DMHIIBIA_01152 5.35e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
DMHIIBIA_01153 4.81e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
DMHIIBIA_01154 1.76e-47 - - - K - - - SpoVT / AbrB like domain
DMHIIBIA_01156 1.18e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMHIIBIA_01157 2.43e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
DMHIIBIA_01158 1.43e-163 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
DMHIIBIA_01159 7.6e-269 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DMHIIBIA_01160 4.67e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DMHIIBIA_01162 1.65e-244 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
DMHIIBIA_01163 1.64e-132 - - - S - - - Helix-turn-helix domain
DMHIIBIA_01164 2.71e-124 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
DMHIIBIA_01167 2.38e-18 - - - S - - - Cro/C1-type HTH DNA-binding domain
DMHIIBIA_01168 2.58e-33 - - - - - - - -
DMHIIBIA_01172 4.84e-14 - - - - - - - -
DMHIIBIA_01174 2.43e-147 - - - - - - - -
DMHIIBIA_01176 1.26e-36 - - - - - - - -
DMHIIBIA_01178 2e-25 - - - - - - - -
DMHIIBIA_01185 8.98e-212 - - - D - - - phage tail tape measure protein
DMHIIBIA_01186 4.33e-14 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
DMHIIBIA_01187 1.19e-41 - - - S - - - KTSC domain
DMHIIBIA_01189 1.15e-28 - - - - - - - -
DMHIIBIA_01190 0.0 - - - S - - - Bacterial EndoU nuclease
DMHIIBIA_01193 4.47e-76 - - - E - - - Glyoxalase-like domain
DMHIIBIA_01195 8.73e-206 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
DMHIIBIA_01196 1.81e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
DMHIIBIA_01197 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
DMHIIBIA_01198 4.3e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_01199 5.44e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
DMHIIBIA_01200 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
DMHIIBIA_01201 1.51e-235 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
DMHIIBIA_01202 6.79e-271 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DMHIIBIA_01203 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMHIIBIA_01204 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_01205 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DMHIIBIA_01206 1.19e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DMHIIBIA_01207 9.38e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
DMHIIBIA_01209 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
DMHIIBIA_01210 1.57e-30 yjfB - - S - - - Putative motility protein
DMHIIBIA_01211 8.23e-88 yjgA - - T - - - Protein of unknown function (DUF2809)
DMHIIBIA_01212 5.57e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
DMHIIBIA_01213 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
DMHIIBIA_01214 8.96e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
DMHIIBIA_01215 2.98e-287 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DMHIIBIA_01216 9.09e-281 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DMHIIBIA_01217 1.73e-40 - - - - - - - -
DMHIIBIA_01218 4.39e-182 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
DMHIIBIA_01219 1.19e-157 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
DMHIIBIA_01220 7.87e-165 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01221 1.54e-222 yjlA - - EG - - - Putative multidrug resistance efflux transporter
DMHIIBIA_01222 1.22e-118 yjlB - - S - - - Cupin domain
DMHIIBIA_01223 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
DMHIIBIA_01224 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DMHIIBIA_01225 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
DMHIIBIA_01226 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
DMHIIBIA_01227 5.66e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
DMHIIBIA_01228 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
DMHIIBIA_01229 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
DMHIIBIA_01230 2.6e-112 - - - T - - - Transcriptional regulatory protein, C terminal
DMHIIBIA_01231 1.05e-168 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DMHIIBIA_01232 8.54e-130 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_01233 1.03e-83 - - - S - - - ABC-2 family transporter protein
DMHIIBIA_01235 1.85e-51 - 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_01236 4.43e-76 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_01238 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
DMHIIBIA_01239 2.75e-281 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
DMHIIBIA_01242 1.3e-242 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
DMHIIBIA_01243 1.86e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
DMHIIBIA_01244 4.85e-102 yjoA - - S - - - DinB family
DMHIIBIA_01245 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
DMHIIBIA_01247 8.26e-222 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DMHIIBIA_01248 2.73e-80 yjqA - - S - - - Bacterial PH domain
DMHIIBIA_01249 4.37e-141 yjqB - - S - - - phage-related replication protein
DMHIIBIA_01251 7.61e-144 xkdA - - E - - - IrrE N-terminal-like domain
DMHIIBIA_01252 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
DMHIIBIA_01254 8.08e-192 xkdC - - L - - - Bacterial dnaA protein
DMHIIBIA_01258 2.15e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
DMHIIBIA_01259 2.38e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
DMHIIBIA_01260 3.51e-265 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
DMHIIBIA_01261 7.29e-303 xkdE3 - - S - - - portal protein
DMHIIBIA_01262 2.52e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
DMHIIBIA_01263 2.9e-203 xkdG - - S - - - Phage capsid family
DMHIIBIA_01264 4.38e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
DMHIIBIA_01265 2.02e-56 - - - S - - - Domain of unknown function (DUF3599)
DMHIIBIA_01266 4.86e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
DMHIIBIA_01267 4.99e-73 xkdJ - - - - - - -
DMHIIBIA_01268 3.86e-21 - - - - - - - -
DMHIIBIA_01269 8.06e-288 xkdK - - S - - - Phage tail sheath C-terminal domain
DMHIIBIA_01270 8.21e-97 xkdM - - S - - - Phage tail tube protein
DMHIIBIA_01271 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
DMHIIBIA_01272 4.33e-27 - - - - - - - -
DMHIIBIA_01273 4.11e-288 xkdO - - L - - - Transglycosylase SLT domain
DMHIIBIA_01274 4.62e-145 xkdP - - S - - - Lysin motif
DMHIIBIA_01275 8.89e-205 xkdQ - - G - - - NLP P60 protein
DMHIIBIA_01276 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
DMHIIBIA_01277 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
DMHIIBIA_01278 1.08e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DMHIIBIA_01279 2.03e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
DMHIIBIA_01280 3.63e-37 - - - - - - - -
DMHIIBIA_01281 3.12e-110 - - - - - - - -
DMHIIBIA_01283 1.55e-38 xkdX - - - - - - -
DMHIIBIA_01284 7.1e-175 xepA - - - - - - -
DMHIIBIA_01285 3.87e-51 xhlA - - S - - - Haemolysin XhlA
DMHIIBIA_01286 4.7e-52 xhlB - - S - - - SPP1 phage holin
DMHIIBIA_01287 3.49e-215 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
DMHIIBIA_01288 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
DMHIIBIA_01289 7.37e-170 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
DMHIIBIA_01290 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
DMHIIBIA_01291 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
DMHIIBIA_01292 9.38e-312 steT - - E ko:K03294 - ko00000 amino acid
DMHIIBIA_01293 3.53e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DMHIIBIA_01294 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DMHIIBIA_01295 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DMHIIBIA_01297 1.77e-274 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMHIIBIA_01298 0.0 yubD - - P - - - Major Facilitator Superfamily
DMHIIBIA_01299 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
DMHIIBIA_01300 2.3e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01301 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMHIIBIA_01302 9.2e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01303 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DMHIIBIA_01304 3.4e-227 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
DMHIIBIA_01305 3.53e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
DMHIIBIA_01306 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DMHIIBIA_01307 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_01308 3.43e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
DMHIIBIA_01309 2.42e-203 ykgA - - E - - - Amidinotransferase
DMHIIBIA_01310 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
DMHIIBIA_01311 8.68e-129 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DMHIIBIA_01312 3.36e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
DMHIIBIA_01313 1.73e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
DMHIIBIA_01314 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
DMHIIBIA_01315 4.35e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMHIIBIA_01316 2.18e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMHIIBIA_01317 7.71e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
DMHIIBIA_01318 7.1e-94 ohrR - - K - - - COG1846 Transcriptional regulators
DMHIIBIA_01319 1.92e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
DMHIIBIA_01320 2.33e-75 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMHIIBIA_01322 1.43e-274 - - - M - - - Glycosyl transferase family 2
DMHIIBIA_01323 1.68e-175 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
DMHIIBIA_01324 1.09e-274 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_01325 2.97e-157 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
DMHIIBIA_01326 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DMHIIBIA_01327 7.39e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DMHIIBIA_01328 2.12e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DMHIIBIA_01329 6.53e-171 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
DMHIIBIA_01330 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_01331 4.66e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
DMHIIBIA_01332 3.63e-309 ydhD - - M - - - Glycosyl hydrolase
DMHIIBIA_01334 2.89e-308 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
DMHIIBIA_01335 1.23e-69 tnrA - - K - - - transcriptional
DMHIIBIA_01336 1.11e-23 - - - - - - - -
DMHIIBIA_01337 5.25e-37 ykoL - - - - - - -
DMHIIBIA_01338 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
DMHIIBIA_01339 7.68e-129 ykoP - - G - - - polysaccharide deacetylase
DMHIIBIA_01340 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
DMHIIBIA_01341 3.83e-199 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DMHIIBIA_01342 1.12e-128 ykoX - - S - - - membrane-associated protein
DMHIIBIA_01343 7.98e-171 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
DMHIIBIA_01344 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_01345 3.6e-237 ykrI - - S - - - Anti-sigma factor N-terminus
DMHIIBIA_01346 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
DMHIIBIA_01347 9.35e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
DMHIIBIA_01348 1.05e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
DMHIIBIA_01349 3.8e-308 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
DMHIIBIA_01350 4.08e-146 - - - S - - - Protein of unknown function (DUF421)
DMHIIBIA_01351 1.78e-31 ykzE - - - - - - -
DMHIIBIA_01352 1.52e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
DMHIIBIA_01353 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_01354 6.51e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMHIIBIA_01356 1.09e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DMHIIBIA_01357 1.65e-285 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DMHIIBIA_01358 2.72e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DMHIIBIA_01359 8.56e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DMHIIBIA_01360 2.62e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
DMHIIBIA_01361 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DMHIIBIA_01362 2.15e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
DMHIIBIA_01363 7.15e-122 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DMHIIBIA_01365 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
DMHIIBIA_01366 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
DMHIIBIA_01367 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
DMHIIBIA_01368 4.74e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
DMHIIBIA_01369 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
DMHIIBIA_01370 5.19e-230 ykvI - - S - - - membrane
DMHIIBIA_01371 6.02e-250 - - - - - - - -
DMHIIBIA_01372 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMHIIBIA_01373 1.26e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
DMHIIBIA_01374 5.06e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DMHIIBIA_01375 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DMHIIBIA_01376 1.04e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
DMHIIBIA_01377 5.43e-35 ykvS - - S - - - protein conserved in bacteria
DMHIIBIA_01378 2.92e-38 - - - - - - - -
DMHIIBIA_01379 8.42e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
DMHIIBIA_01380 7.63e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_01381 2.46e-113 stoA - - CO - - - thiol-disulfide
DMHIIBIA_01382 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
DMHIIBIA_01383 5.5e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
DMHIIBIA_01385 6.8e-223 ykvZ - - K - - - Transcriptional regulator
DMHIIBIA_01386 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
DMHIIBIA_01387 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_01388 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
DMHIIBIA_01389 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMHIIBIA_01390 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01391 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
DMHIIBIA_01392 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DMHIIBIA_01393 4.69e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
DMHIIBIA_01394 1.74e-160 ykwD - - J - - - protein with SCP PR1 domains
DMHIIBIA_01395 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DMHIIBIA_01396 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_01397 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DMHIIBIA_01398 6.38e-15 - - - - - - - -
DMHIIBIA_01399 4.75e-214 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
DMHIIBIA_01400 5.07e-108 ykyB - - S - - - YkyB-like protein
DMHIIBIA_01401 5.37e-307 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_01402 8.88e-117 ykuD - - S - - - protein conserved in bacteria
DMHIIBIA_01403 2.12e-196 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
DMHIIBIA_01404 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_01406 2.21e-296 ykuI - - T - - - Diguanylate phosphodiesterase
DMHIIBIA_01407 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
DMHIIBIA_01408 2.52e-119 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
DMHIIBIA_01409 3.09e-35 ykzF - - S - - - Antirepressor AbbA
DMHIIBIA_01410 8.55e-99 ykuL - - S - - - CBS domain
DMHIIBIA_01411 5.36e-215 ccpC - - K - - - Transcriptional regulator
DMHIIBIA_01412 6.36e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
DMHIIBIA_01413 5.76e-212 ykuO - - - - - - -
DMHIIBIA_01414 5.1e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
DMHIIBIA_01415 1.19e-121 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DMHIIBIA_01416 3.25e-275 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DMHIIBIA_01417 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
DMHIIBIA_01418 1.48e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
DMHIIBIA_01419 2.51e-98 ykuV - - CO - - - thiol-disulfide
DMHIIBIA_01420 3.04e-126 rok - - K - - - Repressor of ComK
DMHIIBIA_01421 1.98e-215 yknT - - - ko:K06437 - ko00000 -
DMHIIBIA_01422 9.54e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DMHIIBIA_01423 1.64e-239 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DMHIIBIA_01424 3.94e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
DMHIIBIA_01425 1.26e-119 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
DMHIIBIA_01426 8.37e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
DMHIIBIA_01427 3.43e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DMHIIBIA_01428 1.89e-139 yknW - - S - - - Yip1 domain
DMHIIBIA_01429 7.77e-244 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMHIIBIA_01430 1.96e-156 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_01431 3.47e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
DMHIIBIA_01432 1.32e-169 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01433 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
DMHIIBIA_01434 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
DMHIIBIA_01435 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DMHIIBIA_01436 4.3e-49 ykoA - - - - - - -
DMHIIBIA_01437 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DMHIIBIA_01438 4.91e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMHIIBIA_01439 7.76e-299 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
DMHIIBIA_01440 4.47e-18 - - - S - - - Uncharacterized protein YkpC
DMHIIBIA_01441 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
DMHIIBIA_01442 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
DMHIIBIA_01443 1.61e-310 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
DMHIIBIA_01444 2.93e-194 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
DMHIIBIA_01445 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
DMHIIBIA_01446 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DMHIIBIA_01447 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMHIIBIA_01448 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
DMHIIBIA_01449 2.5e-186 ykrA - - S - - - hydrolases of the HAD superfamily
DMHIIBIA_01450 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DMHIIBIA_01451 1.21e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
DMHIIBIA_01452 7.62e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
DMHIIBIA_01453 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_01454 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01455 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
DMHIIBIA_01456 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01457 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01458 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01459 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01460 0.0 - - - IQ - - - Phosphopantetheine attachment site
DMHIIBIA_01461 4.54e-265 - - - V - - - Beta-lactamase
DMHIIBIA_01462 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DMHIIBIA_01463 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DMHIIBIA_01464 8.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DMHIIBIA_01465 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DMHIIBIA_01466 5.61e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
DMHIIBIA_01467 7.38e-185 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
DMHIIBIA_01468 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
DMHIIBIA_01469 1.9e-56 yktA - - S - - - Belongs to the UPF0223 family
DMHIIBIA_01470 3.32e-154 yktB - - S - - - Belongs to the UPF0637 family
DMHIIBIA_01471 7.89e-32 ykzI - - - - - - -
DMHIIBIA_01472 3.31e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
DMHIIBIA_01473 5.32e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
DMHIIBIA_01474 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
DMHIIBIA_01475 1.59e-233 ylaA - - - - - - -
DMHIIBIA_01476 2.12e-58 ylaB - - - - - - -
DMHIIBIA_01477 3.18e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_01479 1.5e-54 ylaE - - - - - - -
DMHIIBIA_01480 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
DMHIIBIA_01481 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
DMHIIBIA_01482 4.05e-64 - - - S - - - YlaH-like protein
DMHIIBIA_01483 1.37e-45 ylaI - - S - - - protein conserved in bacteria
DMHIIBIA_01484 1.83e-136 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DMHIIBIA_01485 1.05e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
DMHIIBIA_01486 7.13e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DMHIIBIA_01487 8.95e-222 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
DMHIIBIA_01488 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
DMHIIBIA_01489 2.02e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DMHIIBIA_01490 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMHIIBIA_01491 8.16e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
DMHIIBIA_01492 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DMHIIBIA_01493 3.95e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
DMHIIBIA_01494 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMHIIBIA_01495 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
DMHIIBIA_01496 6.85e-67 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
DMHIIBIA_01497 3.45e-210 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
DMHIIBIA_01498 1.68e-78 ylbA - - S - - - YugN-like family
DMHIIBIA_01499 3.35e-96 ylbB - - T - - - COG0517 FOG CBS domain
DMHIIBIA_01500 3.26e-254 ylbC - - S - - - protein with SCP PR1 domains
DMHIIBIA_01501 1.64e-84 ylbD - - S - - - Putative coat protein
DMHIIBIA_01502 1.73e-48 ylbE - - S - - - YlbE-like protein
DMHIIBIA_01503 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
DMHIIBIA_01504 2.78e-57 ylbG - - S - - - UPF0298 protein
DMHIIBIA_01506 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
DMHIIBIA_01507 1.13e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DMHIIBIA_01508 9.73e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
DMHIIBIA_01509 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
DMHIIBIA_01510 1.52e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
DMHIIBIA_01511 1.01e-292 ylbM - - S - - - Belongs to the UPF0348 family
DMHIIBIA_01512 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
DMHIIBIA_01513 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
DMHIIBIA_01514 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
DMHIIBIA_01515 1.33e-115 ylbP - - K - - - n-acetyltransferase
DMHIIBIA_01516 2.79e-209 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMHIIBIA_01517 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DMHIIBIA_01518 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
DMHIIBIA_01519 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DMHIIBIA_01520 2.4e-68 ftsL - - D - - - Essential cell division protein
DMHIIBIA_01521 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DMHIIBIA_01522 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
DMHIIBIA_01523 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMHIIBIA_01524 8.22e-221 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMHIIBIA_01525 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMHIIBIA_01526 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DMHIIBIA_01527 5.69e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMHIIBIA_01528 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
DMHIIBIA_01529 1.04e-176 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DMHIIBIA_01530 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DMHIIBIA_01531 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMHIIBIA_01532 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
DMHIIBIA_01533 1.31e-214 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
DMHIIBIA_01534 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_01535 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_01536 2.21e-184 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
DMHIIBIA_01537 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
DMHIIBIA_01538 7.13e-52 ylmC - - S - - - sporulation protein
DMHIIBIA_01539 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
DMHIIBIA_01540 1.05e-160 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMHIIBIA_01541 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DMHIIBIA_01542 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
DMHIIBIA_01543 4.13e-180 ylmH - - S - - - conserved protein, contains S4-like domain
DMHIIBIA_01544 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
DMHIIBIA_01545 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMHIIBIA_01546 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
DMHIIBIA_01547 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DMHIIBIA_01548 5.13e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
DMHIIBIA_01549 6.32e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMHIIBIA_01550 1.14e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
DMHIIBIA_01551 1.64e-210 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
DMHIIBIA_01552 2.12e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DMHIIBIA_01553 8.86e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DMHIIBIA_01554 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
DMHIIBIA_01555 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DMHIIBIA_01556 2.02e-219 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DMHIIBIA_01557 1.05e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DMHIIBIA_01558 1.49e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMHIIBIA_01559 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
DMHIIBIA_01560 3.87e-225 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
DMHIIBIA_01561 3.06e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
DMHIIBIA_01562 9.22e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
DMHIIBIA_01563 2.81e-183 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
DMHIIBIA_01564 1.39e-185 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
DMHIIBIA_01565 2.01e-102 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
DMHIIBIA_01566 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
DMHIIBIA_01567 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
DMHIIBIA_01568 2.5e-197 yloC - - S - - - stress-induced protein
DMHIIBIA_01569 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
DMHIIBIA_01570 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
DMHIIBIA_01571 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DMHIIBIA_01572 2.18e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMHIIBIA_01573 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMHIIBIA_01574 1.18e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DMHIIBIA_01575 2.08e-218 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMHIIBIA_01576 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DMHIIBIA_01577 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DMHIIBIA_01578 4.98e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
DMHIIBIA_01579 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
DMHIIBIA_01580 2.53e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DMHIIBIA_01581 1.24e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
DMHIIBIA_01582 1.3e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
DMHIIBIA_01583 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
DMHIIBIA_01584 3.65e-78 yloU - - S - - - protein conserved in bacteria
DMHIIBIA_01585 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
DMHIIBIA_01586 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
DMHIIBIA_01587 9.75e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
DMHIIBIA_01588 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMHIIBIA_01589 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
DMHIIBIA_01590 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DMHIIBIA_01591 2.17e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_01592 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
DMHIIBIA_01593 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMHIIBIA_01594 1.43e-172 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DMHIIBIA_01595 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
DMHIIBIA_01596 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DMHIIBIA_01597 5.63e-178 - - - S - - - Phosphotransferase enzyme family
DMHIIBIA_01598 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DMHIIBIA_01599 9.92e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMHIIBIA_01600 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
DMHIIBIA_01601 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
DMHIIBIA_01602 3.41e-80 ylqD - - S - - - YlqD protein
DMHIIBIA_01603 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DMHIIBIA_01604 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
DMHIIBIA_01605 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DMHIIBIA_01606 4.19e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DMHIIBIA_01607 6.81e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMHIIBIA_01608 0.0 ylqG - - - - - - -
DMHIIBIA_01609 6.94e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
DMHIIBIA_01610 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DMHIIBIA_01611 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMHIIBIA_01612 2.1e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
DMHIIBIA_01613 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DMHIIBIA_01614 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DMHIIBIA_01615 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
DMHIIBIA_01616 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DMHIIBIA_01617 8.9e-317 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DMHIIBIA_01618 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DMHIIBIA_01619 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
DMHIIBIA_01620 2.63e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
DMHIIBIA_01621 1.45e-48 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
DMHIIBIA_01622 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
DMHIIBIA_01623 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DMHIIBIA_01624 2.66e-120 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
DMHIIBIA_01625 1.05e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
DMHIIBIA_01626 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
DMHIIBIA_01627 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
DMHIIBIA_01628 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
DMHIIBIA_01629 1.8e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
DMHIIBIA_01630 4.62e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
DMHIIBIA_01631 6.59e-81 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
DMHIIBIA_01632 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DMHIIBIA_01633 6.97e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DMHIIBIA_01634 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
DMHIIBIA_01635 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
DMHIIBIA_01636 8.55e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
DMHIIBIA_01637 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
DMHIIBIA_01638 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
DMHIIBIA_01639 1.03e-241 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DMHIIBIA_01640 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DMHIIBIA_01641 1.79e-246 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
DMHIIBIA_01642 7.73e-201 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
DMHIIBIA_01643 6.77e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
DMHIIBIA_01644 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
DMHIIBIA_01645 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
DMHIIBIA_01646 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
DMHIIBIA_01647 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
DMHIIBIA_01648 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_01649 3.52e-91 ylxL - - - - - - -
DMHIIBIA_01650 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
DMHIIBIA_01651 9.41e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMHIIBIA_01652 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
DMHIIBIA_01653 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DMHIIBIA_01654 2.22e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMHIIBIA_01655 2.2e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
DMHIIBIA_01656 2.2e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DMHIIBIA_01657 4.66e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
DMHIIBIA_01658 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DMHIIBIA_01659 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMHIIBIA_01660 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
DMHIIBIA_01661 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
DMHIIBIA_01662 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
DMHIIBIA_01663 6.16e-63 ylxQ - - J - - - ribosomal protein
DMHIIBIA_01664 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMHIIBIA_01665 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
DMHIIBIA_01666 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMHIIBIA_01667 4.96e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMHIIBIA_01668 3.69e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
DMHIIBIA_01669 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMHIIBIA_01670 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DMHIIBIA_01671 1.19e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
DMHIIBIA_01672 2.41e-298 mlpA - - S - - - Belongs to the peptidase M16 family
DMHIIBIA_01673 2.17e-56 ymxH - - S - - - YlmC YmxH family
DMHIIBIA_01674 3.86e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
DMHIIBIA_01675 1.93e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
DMHIIBIA_01676 4.09e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMHIIBIA_01677 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DMHIIBIA_01678 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMHIIBIA_01679 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DMHIIBIA_01680 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
DMHIIBIA_01681 6.32e-42 - - - S - - - YlzJ-like protein
DMHIIBIA_01682 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DMHIIBIA_01683 2.59e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01684 7.1e-293 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_01685 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_01686 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
DMHIIBIA_01687 5.34e-305 albE - - S - - - Peptidase M16
DMHIIBIA_01688 3.77e-306 ymfH - - S - - - zinc protease
DMHIIBIA_01689 6.79e-163 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
DMHIIBIA_01690 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
DMHIIBIA_01691 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
DMHIIBIA_01692 2.42e-175 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
DMHIIBIA_01693 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMHIIBIA_01694 7.69e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
DMHIIBIA_01695 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMHIIBIA_01696 2.22e-278 pbpX - - V - - - Beta-lactamase
DMHIIBIA_01697 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
DMHIIBIA_01698 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
DMHIIBIA_01699 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
DMHIIBIA_01700 3.94e-249 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
DMHIIBIA_01701 5e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DMHIIBIA_01702 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMHIIBIA_01703 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
DMHIIBIA_01704 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
DMHIIBIA_01705 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMHIIBIA_01706 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMHIIBIA_01707 1.55e-41 - - - - - - - -
DMHIIBIA_01710 3.33e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
DMHIIBIA_01711 7.83e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_01712 2.6e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
DMHIIBIA_01713 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_01714 1.46e-46 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
DMHIIBIA_01715 1.73e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
DMHIIBIA_01716 4.33e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
DMHIIBIA_01717 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
DMHIIBIA_01718 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
DMHIIBIA_01719 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01720 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_01721 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
DMHIIBIA_01722 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
DMHIIBIA_01723 6.55e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DMHIIBIA_01724 1.74e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
DMHIIBIA_01725 1.28e-152 yoaK - - S - - - Membrane
DMHIIBIA_01726 1.32e-80 ymzB - - - - - - -
DMHIIBIA_01727 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
DMHIIBIA_01728 2.68e-161 ymaC - - S - - - Replication protein
DMHIIBIA_01729 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
DMHIIBIA_01730 3.04e-71 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DMHIIBIA_01731 1.5e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DMHIIBIA_01733 8.12e-75 ymaF - - S - - - YmaF family
DMHIIBIA_01734 4.23e-218 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMHIIBIA_01735 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
DMHIIBIA_01736 4.76e-56 - - - - - - - -
DMHIIBIA_01737 9.42e-29 ymzA - - - - - - -
DMHIIBIA_01738 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
DMHIIBIA_01739 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMHIIBIA_01740 1.52e-239 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMHIIBIA_01741 4.33e-110 ymaB - - S - - - MutT family
DMHIIBIA_01742 2.64e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DMHIIBIA_01743 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
DMHIIBIA_01744 2.21e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMHIIBIA_01745 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
DMHIIBIA_01746 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
DMHIIBIA_01747 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
DMHIIBIA_01748 6.98e-265 mrjp - - G - - - Major royal jelly protein
DMHIIBIA_01749 1.8e-316 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
DMHIIBIA_01750 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
DMHIIBIA_01751 3.32e-264 xylR - - GK - - - ROK family
DMHIIBIA_01752 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
DMHIIBIA_01753 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
DMHIIBIA_01754 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
DMHIIBIA_01758 2.31e-234 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
DMHIIBIA_01761 1.74e-168 yoaP - - K - - - YoaP-like
DMHIIBIA_01762 3.99e-129 - - - J - - - Acetyltransferase (GNAT) domain
DMHIIBIA_01763 2.55e-148 - - - S - - - Domain of unknown function (DUF3885)
DMHIIBIA_01764 3.27e-255 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_01765 4.73e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
DMHIIBIA_01766 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
DMHIIBIA_01768 8.7e-123 yvgO - - - - - - -
DMHIIBIA_01770 0.0 yobO - - M - - - Pectate lyase superfamily protein
DMHIIBIA_01771 1.74e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
DMHIIBIA_01772 1.31e-180 yndL - - S - - - Replication protein
DMHIIBIA_01773 8.63e-12 - - - - - - - -
DMHIIBIA_01774 4.43e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
DMHIIBIA_01775 7.53e-94 yndM - - S - - - Protein of unknown function (DUF2512)
DMHIIBIA_01777 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DMHIIBIA_01778 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
DMHIIBIA_01779 5.22e-145 yneB - - L - - - resolvase
DMHIIBIA_01780 2.33e-43 ynzC - - S - - - UPF0291 protein
DMHIIBIA_01781 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMHIIBIA_01782 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
DMHIIBIA_01783 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
DMHIIBIA_01784 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
DMHIIBIA_01785 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
DMHIIBIA_01786 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
DMHIIBIA_01787 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
DMHIIBIA_01788 1.14e-96 yneK - - S - - - Protein of unknown function (DUF2621)
DMHIIBIA_01789 3.47e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
DMHIIBIA_01790 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
DMHIIBIA_01791 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
DMHIIBIA_01792 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMHIIBIA_01793 1.41e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DMHIIBIA_01794 2.66e-09 - - - S - - - Fur-regulated basic protein B
DMHIIBIA_01796 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
DMHIIBIA_01797 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
DMHIIBIA_01798 3.18e-69 yneQ - - - - - - -
DMHIIBIA_01799 3.13e-65 yneR - - S - - - Belongs to the HesB IscA family
DMHIIBIA_01800 7.46e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DMHIIBIA_01801 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
DMHIIBIA_01802 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DMHIIBIA_01803 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DMHIIBIA_01804 3.14e-19 - - - - - - - -
DMHIIBIA_01805 1.82e-63 ynfC - - - - - - -
DMHIIBIA_01806 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
DMHIIBIA_01807 4.3e-229 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
DMHIIBIA_01808 5.73e-240 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
DMHIIBIA_01809 1.51e-146 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
DMHIIBIA_01810 7.34e-267 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
DMHIIBIA_01811 9.32e-188 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_01812 1.44e-230 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
DMHIIBIA_01813 4.96e-50 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
DMHIIBIA_01814 3.31e-198 yndG - - S - - - DoxX-like family
DMHIIBIA_01815 8.19e-102 - - - S - - - Domain of unknown function (DUF4166)
DMHIIBIA_01816 0.0 yndJ - - S - - - YndJ-like protein
DMHIIBIA_01817 2.26e-41 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
DMHIIBIA_01818 1.21e-21 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
DMHIIBIA_01819 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
DMHIIBIA_01820 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
DMHIIBIA_01821 2.24e-301 - - - T - - - Histidine kinase
DMHIIBIA_01822 2.1e-161 - - - T - - - Transcriptional regulatory protein, C terminal
DMHIIBIA_01823 1.28e-315 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
DMHIIBIA_01824 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
DMHIIBIA_01825 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01826 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01827 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01828 1.28e-276 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_01829 1.6e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
DMHIIBIA_01830 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DMHIIBIA_01831 2.56e-161 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DMHIIBIA_01832 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
DMHIIBIA_01833 6.35e-276 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DMHIIBIA_01834 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMHIIBIA_01835 1.19e-163 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMHIIBIA_01836 1.54e-270 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DMHIIBIA_01837 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
DMHIIBIA_01838 5.24e-183 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DMHIIBIA_01839 9.94e-90 yngA - - S - - - membrane
DMHIIBIA_01840 2.7e-201 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
DMHIIBIA_01841 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
DMHIIBIA_01842 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DMHIIBIA_01843 2.48e-178 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
DMHIIBIA_01844 5.77e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
DMHIIBIA_01845 3.79e-39 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
DMHIIBIA_01846 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
DMHIIBIA_01847 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DMHIIBIA_01848 1.03e-265 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
DMHIIBIA_01849 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
DMHIIBIA_01850 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
DMHIIBIA_01851 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
DMHIIBIA_01852 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01853 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01854 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01855 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
DMHIIBIA_01856 2.16e-236 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
DMHIIBIA_01857 1.75e-310 yoeA - - V - - - MATE efflux family protein
DMHIIBIA_01858 5.23e-125 yoeB - - S - - - IseA DL-endopeptidase inhibitor
DMHIIBIA_01859 8.38e-60 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
DMHIIBIA_01860 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01861 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01862 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_01863 1.01e-87 - - - S - - - Bacterial EndoU nuclease
DMHIIBIA_01864 4.77e-33 - - - S - - - SMI1-KNR4 cell-wall
DMHIIBIA_01866 4.16e-87 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
DMHIIBIA_01867 5.36e-84 - - - S - - - Pfam:Phage_holin_4_1
DMHIIBIA_01870 4.07e-246 - - - S - - - Domain of unknown function (DUF2479)
DMHIIBIA_01871 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
DMHIIBIA_01872 8.43e-291 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
DMHIIBIA_01873 3.77e-139 - - - S - - - Phage tail protein
DMHIIBIA_01874 0.0 - - - S - - - peptidoglycan catabolic process
DMHIIBIA_01875 1.25e-16 - - - - - - - -
DMHIIBIA_01876 8.17e-32 - - - - - - - -
DMHIIBIA_01877 7.1e-78 - - - - - - - -
DMHIIBIA_01878 2.86e-40 - - - - - - - -
DMHIIBIA_01879 2.18e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
DMHIIBIA_01880 3.53e-19 - - - S - - - Phage head-tail joining protein
DMHIIBIA_01881 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
DMHIIBIA_01882 3.09e-62 - - - S - - - peptidoglycan catabolic process
DMHIIBIA_01883 7.43e-09 - - - - - - - -
DMHIIBIA_01884 8.05e-226 - - - S - - - capsid protein
DMHIIBIA_01885 2.5e-139 - - - S - - - peptidase activity
DMHIIBIA_01886 2.44e-305 - - - S - - - Phage portal protein
DMHIIBIA_01887 1.56e-14 - - - - - - - -
DMHIIBIA_01888 3.89e-291 - - - S - - - Phage Terminase
DMHIIBIA_01889 2.34e-113 - - - S - - - Phage terminase, small subunit
DMHIIBIA_01891 7.82e-93 - - - S - - - HNH endonuclease
DMHIIBIA_01892 4.21e-20 - - - - - - - -
DMHIIBIA_01893 3.43e-59 - - - F - - - nucleoside 2-deoxyribosyltransferase
DMHIIBIA_01894 7.57e-93 - - - L - - - Phage integrase family
DMHIIBIA_01895 7.89e-68 - - - M - - - ArpU family transcriptional regulator
DMHIIBIA_01897 7.55e-66 - - - D - - - nuclear chromosome segregation
DMHIIBIA_01899 1.04e-59 - - - - - - - -
DMHIIBIA_01901 9.31e-89 - - - - - - - -
DMHIIBIA_01903 1.74e-10 - - - - - - - -
DMHIIBIA_01905 4.55e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
DMHIIBIA_01909 2.1e-36 - - - - - - - -
DMHIIBIA_01912 8.33e-45 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
DMHIIBIA_01913 1.71e-116 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
DMHIIBIA_01915 9.11e-50 - - - S - - - Domain of unknown function (DUF771)
DMHIIBIA_01916 5.63e-07 ahdIC - - K - - - PFAM helix-turn-helix domain protein
DMHIIBIA_01917 3.44e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
DMHIIBIA_01920 1.35e-82 - - - - - - - -
DMHIIBIA_01921 7.04e-146 - - - L - - - Phage integrase family
DMHIIBIA_01923 3.97e-125 - - - L - - - Integrase
DMHIIBIA_01924 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
DMHIIBIA_01925 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
DMHIIBIA_01926 1.13e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
DMHIIBIA_01927 3.29e-67 - - - K - - - Helix-turn-helix domain
DMHIIBIA_01928 7.9e-16 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMHIIBIA_01929 1.44e-196 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01930 1.34e-234 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
DMHIIBIA_01931 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
DMHIIBIA_01932 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
DMHIIBIA_01933 1.7e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_01934 2.31e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMHIIBIA_01935 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMHIIBIA_01936 8.08e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
DMHIIBIA_01937 2.43e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_01938 7.75e-53 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DMHIIBIA_01939 4.6e-171 yoxB - - - - - - -
DMHIIBIA_01940 6.33e-261 yoaB - - EGP - - - the major facilitator superfamily
DMHIIBIA_01941 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
DMHIIBIA_01942 1.8e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMHIIBIA_01943 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DMHIIBIA_01944 6.1e-124 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_01945 4.7e-57 - - - - - - - -
DMHIIBIA_01946 4.97e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DMHIIBIA_01947 5.86e-80 ykvN - - K - - - Transcriptional regulator
DMHIIBIA_01948 5.01e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
DMHIIBIA_01949 1.45e-170 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
DMHIIBIA_01950 1.53e-121 yobS - - K - - - Transcriptional regulator
DMHIIBIA_01951 3.84e-172 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DMHIIBIA_01952 1.57e-118 yobW - - - - - - -
DMHIIBIA_01953 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
DMHIIBIA_01954 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DMHIIBIA_01955 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
DMHIIBIA_01956 1.37e-178 - - - J - - - Protein required for attachment to host cells
DMHIIBIA_01957 3.78e-122 yocC - - - - - - -
DMHIIBIA_01958 1.11e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
DMHIIBIA_01960 1.46e-160 yocH - - M - - - COG1388 FOG LysM repeat
DMHIIBIA_01961 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
DMHIIBIA_01962 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMHIIBIA_01964 2.48e-76 yocK - - T - - - general stress protein
DMHIIBIA_01965 2.71e-13 yocL - - - - - - -
DMHIIBIA_01967 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DMHIIBIA_01968 9.63e-60 yozN - - - - - - -
DMHIIBIA_01969 6.36e-50 yocN - - - - - - -
DMHIIBIA_01970 5.32e-75 yozO - - S - - - Bacterial PH domain
DMHIIBIA_01972 1.35e-42 yozC - - - - - - -
DMHIIBIA_01973 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DMHIIBIA_01974 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
DMHIIBIA_01975 1.94e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
DMHIIBIA_01976 1.98e-296 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DMHIIBIA_01977 1.83e-212 yocS - - S ko:K03453 - ko00000 -transporter
DMHIIBIA_01978 7.15e-177 - - - S - - - Metallo-beta-lactamase superfamily
DMHIIBIA_01979 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
DMHIIBIA_01980 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
DMHIIBIA_01981 0.0 yojO - - P - - - Von Willebrand factor
DMHIIBIA_01982 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
DMHIIBIA_01983 4.23e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DMHIIBIA_01984 1.37e-289 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DMHIIBIA_01985 1.11e-283 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
DMHIIBIA_01986 4.69e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DMHIIBIA_01988 9.95e-303 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
DMHIIBIA_01989 5.03e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DMHIIBIA_01990 2.24e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
DMHIIBIA_01991 3.3e-79 yojF - - S - - - Protein of unknown function (DUF1806)
DMHIIBIA_01992 3.94e-30 - - - - - - - -
DMHIIBIA_01993 5.73e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
DMHIIBIA_01994 1.91e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
DMHIIBIA_01996 1.05e-88 iolK - - S - - - tautomerase
DMHIIBIA_01997 2.97e-89 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
DMHIIBIA_01998 2.42e-74 yodB - - K - - - transcriptional
DMHIIBIA_01999 7.79e-138 yodC - - C - - - nitroreductase
DMHIIBIA_02000 2.84e-139 yahD - - S ko:K06999 - ko00000 Carboxylesterase
DMHIIBIA_02001 2.2e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DMHIIBIA_02002 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
DMHIIBIA_02003 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMHIIBIA_02004 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
DMHIIBIA_02005 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DMHIIBIA_02006 3.53e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_02007 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
DMHIIBIA_02008 4.31e-166 yodH - - Q - - - Methyltransferase
DMHIIBIA_02009 8.71e-33 yodI - - - - - - -
DMHIIBIA_02010 4.49e-192 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
DMHIIBIA_02011 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
DMHIIBIA_02013 1.16e-72 yodL - - S - - - YodL-like
DMHIIBIA_02014 1.76e-132 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
DMHIIBIA_02015 9.77e-34 yozD - - S - - - YozD-like protein
DMHIIBIA_02017 1.9e-161 yodN - - - - - - -
DMHIIBIA_02018 1e-47 yozE - - S - - - Belongs to the UPF0346 family
DMHIIBIA_02019 2.83e-62 yokU - - S - - - YokU-like protein, putative antitoxin
DMHIIBIA_02020 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
DMHIIBIA_02021 2.49e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
DMHIIBIA_02022 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
DMHIIBIA_02023 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DMHIIBIA_02024 9.76e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DMHIIBIA_02025 1.33e-309 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMHIIBIA_02026 3.97e-82 - - - L - - - Bacterial transcription activator, effector binding domain
DMHIIBIA_02028 8.11e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
DMHIIBIA_02029 1.26e-306 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
DMHIIBIA_02030 7.84e-61 cgeC - - - ko:K06321 - ko00000 -
DMHIIBIA_02031 1e-86 cgeA - - - ko:K06319 - ko00000 -
DMHIIBIA_02032 1.21e-219 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
DMHIIBIA_02033 7.47e-281 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
DMHIIBIA_02034 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
DMHIIBIA_02040 5.37e-101 - - - - - - - -
DMHIIBIA_02041 4.26e-25 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
DMHIIBIA_02045 7.54e-99 yoqH - - M - - - LysM domain
DMHIIBIA_02046 3.09e-266 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DMHIIBIA_02049 5.1e-159 - - - S - - - amine dehydrogenase activity
DMHIIBIA_02053 2.68e-39 - - - S - - - Acetyltransferase (GNAT) domain
DMHIIBIA_02054 1.23e-113 yokK - - S - - - SMI1 / KNR4 family
DMHIIBIA_02055 3.88e-68 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
DMHIIBIA_02056 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DMHIIBIA_02057 2.39e-100 yokH - - G - - - SMI1 / KNR4 family
DMHIIBIA_02059 0.0 yokA - - L - - - Recombinase
DMHIIBIA_02060 1.98e-133 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
DMHIIBIA_02061 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
DMHIIBIA_02062 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMHIIBIA_02063 3.35e-89 ypoP - - K - - - transcriptional
DMHIIBIA_02064 6.53e-125 ypmS - - S - - - protein conserved in bacteria
DMHIIBIA_02065 1.43e-173 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
DMHIIBIA_02066 2.43e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
DMHIIBIA_02067 7.13e-52 ypmP - - S - - - Protein of unknown function (DUF2535)
DMHIIBIA_02068 8.57e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMHIIBIA_02069 1.59e-221 yplP - - K - - - Transcriptional regulator
DMHIIBIA_02070 5.24e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
DMHIIBIA_02071 4.71e-148 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DMHIIBIA_02072 3.66e-118 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DMHIIBIA_02073 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DMHIIBIA_02074 2.17e-146 ypjP - - S - - - YpjP-like protein
DMHIIBIA_02075 7.05e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
DMHIIBIA_02076 1.13e-97 yphP - - S - - - Belongs to the UPF0403 family
DMHIIBIA_02077 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
DMHIIBIA_02078 1.27e-200 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
DMHIIBIA_02079 3.97e-129 yagB - - S ko:K06950 - ko00000 phosphohydrolase
DMHIIBIA_02080 5.36e-111 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
DMHIIBIA_02081 7.71e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMHIIBIA_02082 9e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
DMHIIBIA_02083 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
DMHIIBIA_02084 5.19e-17 degR - - - - - - -
DMHIIBIA_02085 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
DMHIIBIA_02086 6.59e-40 ypeQ - - S - - - Zinc-finger
DMHIIBIA_02087 8.39e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
DMHIIBIA_02088 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DMHIIBIA_02089 2.47e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
DMHIIBIA_02091 3.19e-208 ypcP - - L - - - 5'3' exonuclease
DMHIIBIA_02092 2.44e-10 - - - - - - - -
DMHIIBIA_02093 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
DMHIIBIA_02094 0.0 ypbR - - S - - - Dynamin family
DMHIIBIA_02095 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
DMHIIBIA_02096 1.35e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
DMHIIBIA_02097 1.2e-134 - - - J - - - Acetyltransferase (GNAT) domain
DMHIIBIA_02098 1.17e-65 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
DMHIIBIA_02099 6.89e-08 - - - S - - - Bacillus cereus group antimicrobial protein
DMHIIBIA_02100 2.87e-28 ydfR - - S - - - Protein of unknown function (DUF421)
DMHIIBIA_02101 1.56e-41 ydfR - - S - - - Protein of unknown function (DUF421)
DMHIIBIA_02102 1.04e-128 yrdC - - Q - - - Isochorismatase family
DMHIIBIA_02103 4.67e-07 - - - - - - - -
DMHIIBIA_02104 1.45e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
DMHIIBIA_02105 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DMHIIBIA_02106 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DMHIIBIA_02107 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
DMHIIBIA_02109 6.91e-31 - - - S - - - YpzG-like protein
DMHIIBIA_02110 3.16e-274 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
DMHIIBIA_02111 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DMHIIBIA_02112 5.42e-128 ypsA - - S - - - Belongs to the UPF0398 family
DMHIIBIA_02113 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
DMHIIBIA_02115 2.45e-287 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
DMHIIBIA_02116 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
DMHIIBIA_02117 1.3e-28 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
DMHIIBIA_02118 9.93e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
DMHIIBIA_02119 7.23e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DMHIIBIA_02120 9.54e-81 yppG - - S - - - YppG-like protein
DMHIIBIA_02124 0.000542 - - - - ko:K06430 - ko00000 -
DMHIIBIA_02125 2e-239 yppC - - S - - - Protein of unknown function (DUF2515)
DMHIIBIA_02126 7.27e-145 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DMHIIBIA_02127 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DMHIIBIA_02128 1.8e-119 ypoC - - - - - - -
DMHIIBIA_02129 1.7e-156 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMHIIBIA_02130 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
DMHIIBIA_02131 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
DMHIIBIA_02132 1.99e-281 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
DMHIIBIA_02133 5.58e-104 ypmB - - S - - - protein conserved in bacteria
DMHIIBIA_02134 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
DMHIIBIA_02135 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
DMHIIBIA_02136 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMHIIBIA_02137 1.64e-201 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMHIIBIA_02138 2.57e-187 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
DMHIIBIA_02139 3.83e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DMHIIBIA_02140 7.21e-281 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DMHIIBIA_02141 2.55e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
DMHIIBIA_02142 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
DMHIIBIA_02143 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
DMHIIBIA_02144 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DMHIIBIA_02145 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
DMHIIBIA_02146 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_02147 4.06e-289 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
DMHIIBIA_02148 1.96e-180 ypjB - - S - - - sporulation protein
DMHIIBIA_02149 3.59e-134 ypjA - - S - - - membrane
DMHIIBIA_02150 2.33e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
DMHIIBIA_02151 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
DMHIIBIA_02152 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
DMHIIBIA_02153 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
DMHIIBIA_02154 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
DMHIIBIA_02155 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
DMHIIBIA_02156 1.03e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DMHIIBIA_02157 1.39e-257 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
DMHIIBIA_02158 1.5e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMHIIBIA_02159 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DMHIIBIA_02160 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DMHIIBIA_02161 1.68e-146 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
DMHIIBIA_02162 2.36e-167 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
DMHIIBIA_02163 1.37e-210 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMHIIBIA_02164 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMHIIBIA_02165 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
DMHIIBIA_02166 1.11e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMHIIBIA_02167 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMHIIBIA_02168 1.96e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
DMHIIBIA_02169 2.86e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DMHIIBIA_02170 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DMHIIBIA_02171 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DMHIIBIA_02172 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
DMHIIBIA_02173 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
DMHIIBIA_02174 5.15e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
DMHIIBIA_02175 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DMHIIBIA_02176 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DMHIIBIA_02177 2.3e-171 yphF - - - - - - -
DMHIIBIA_02178 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
DMHIIBIA_02179 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
DMHIIBIA_02180 9.53e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
DMHIIBIA_02181 5.09e-135 yphA - - - - - - -
DMHIIBIA_02182 1.87e-12 - - - S - - - YpzI-like protein
DMHIIBIA_02183 2.81e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DMHIIBIA_02184 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
DMHIIBIA_02185 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
DMHIIBIA_02186 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
DMHIIBIA_02187 2.7e-76 ypfA - - M - - - Flagellar protein YcgR
DMHIIBIA_02188 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
DMHIIBIA_02189 3.09e-212 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
DMHIIBIA_02190 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
DMHIIBIA_02191 7.53e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
DMHIIBIA_02192 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DMHIIBIA_02193 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DMHIIBIA_02194 3.69e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
DMHIIBIA_02195 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
DMHIIBIA_02196 1.44e-124 ypbE - - M - - - Lysin motif
DMHIIBIA_02197 1.4e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
DMHIIBIA_02198 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
DMHIIBIA_02199 1.32e-247 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
DMHIIBIA_02200 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
DMHIIBIA_02201 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DMHIIBIA_02202 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMHIIBIA_02203 5.3e-245 rsiX - - - - - - -
DMHIIBIA_02204 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DMHIIBIA_02205 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_02206 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_02207 5.12e-251 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
DMHIIBIA_02208 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
DMHIIBIA_02209 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
DMHIIBIA_02210 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DMHIIBIA_02211 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
DMHIIBIA_02212 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
DMHIIBIA_02213 1.14e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DMHIIBIA_02214 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
DMHIIBIA_02215 7.84e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMHIIBIA_02216 2.85e-164 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DMHIIBIA_02218 5.71e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
DMHIIBIA_02219 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMHIIBIA_02220 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DMHIIBIA_02221 2.99e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMHIIBIA_02222 8.02e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
DMHIIBIA_02223 3.09e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMHIIBIA_02224 2.01e-70 ypuD - - - - - - -
DMHIIBIA_02225 1.81e-128 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DMHIIBIA_02226 5.56e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
DMHIIBIA_02227 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMHIIBIA_02228 3.65e-198 ypuA - - S - - - Secreted protein
DMHIIBIA_02229 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DMHIIBIA_02230 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
DMHIIBIA_02231 7.55e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
DMHIIBIA_02232 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
DMHIIBIA_02233 5.53e-242 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
DMHIIBIA_02234 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
DMHIIBIA_02235 2.03e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
DMHIIBIA_02236 6.68e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
DMHIIBIA_02237 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_02238 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
DMHIIBIA_02239 4e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
DMHIIBIA_02240 3.52e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DMHIIBIA_02241 4.3e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DMHIIBIA_02242 2.36e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
DMHIIBIA_02243 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
DMHIIBIA_02244 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
DMHIIBIA_02245 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
DMHIIBIA_02246 1.01e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
DMHIIBIA_02248 7.29e-46 yqkK - - - - - - -
DMHIIBIA_02249 1.96e-30 - - - - - - - -
DMHIIBIA_02250 3.94e-308 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
DMHIIBIA_02251 1.19e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
DMHIIBIA_02252 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
DMHIIBIA_02253 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
DMHIIBIA_02254 4e-76 ansR - - K - - - Transcriptional regulator
DMHIIBIA_02255 5.91e-280 yqxK - - L - - - DNA helicase
DMHIIBIA_02256 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
DMHIIBIA_02257 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
DMHIIBIA_02258 8.51e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
DMHIIBIA_02259 5.53e-09 yqkE - - S - - - Protein of unknown function (DUF3886)
DMHIIBIA_02260 9.62e-225 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
DMHIIBIA_02261 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
DMHIIBIA_02262 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
DMHIIBIA_02263 3.26e-220 yqkA - - K - - - GrpB protein
DMHIIBIA_02264 3.46e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
DMHIIBIA_02265 1.15e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
DMHIIBIA_02266 5.45e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMHIIBIA_02267 4.21e-72 - - - S - - - YolD-like protein
DMHIIBIA_02269 6.84e-237 yueF - - S - - - transporter activity
DMHIIBIA_02271 1.81e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_02272 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
DMHIIBIA_02273 9.81e-315 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
DMHIIBIA_02274 7.99e-179 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_02275 1.26e-219 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DMHIIBIA_02276 4.98e-186 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMHIIBIA_02277 5.64e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
DMHIIBIA_02278 4.15e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
DMHIIBIA_02279 3.29e-280 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DMHIIBIA_02280 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
DMHIIBIA_02281 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02282 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02283 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02284 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02285 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02286 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02287 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02288 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
DMHIIBIA_02289 1.54e-165 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
DMHIIBIA_02290 4.54e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DMHIIBIA_02293 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DMHIIBIA_02294 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
DMHIIBIA_02295 6.96e-206 - - - K - - - LysR substrate binding domain
DMHIIBIA_02296 2.62e-65 - - - S - - - GlpM protein
DMHIIBIA_02297 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
DMHIIBIA_02298 1.51e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DMHIIBIA_02300 2.66e-218 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DMHIIBIA_02301 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DMHIIBIA_02302 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DMHIIBIA_02303 1.57e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMHIIBIA_02304 1.3e-34 yqzJ - - - - - - -
DMHIIBIA_02305 1.18e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMHIIBIA_02306 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
DMHIIBIA_02307 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DMHIIBIA_02308 1.89e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
DMHIIBIA_02310 2.14e-122 yqjB - - S - - - protein conserved in bacteria
DMHIIBIA_02311 3.22e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
DMHIIBIA_02312 6.07e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DMHIIBIA_02313 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DMHIIBIA_02314 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DMHIIBIA_02315 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
DMHIIBIA_02316 2.87e-217 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DMHIIBIA_02317 2.42e-282 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DMHIIBIA_02318 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DMHIIBIA_02319 1.25e-218 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DMHIIBIA_02320 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DMHIIBIA_02321 9.08e-259 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
DMHIIBIA_02322 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DMHIIBIA_02323 2.27e-193 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
DMHIIBIA_02324 0.0 bkdR - - KT - - - Transcriptional regulator
DMHIIBIA_02325 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
DMHIIBIA_02326 1.56e-202 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DMHIIBIA_02327 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
DMHIIBIA_02328 6.65e-259 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DMHIIBIA_02329 3.81e-255 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
DMHIIBIA_02330 8.75e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
DMHIIBIA_02331 1.87e-270 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
DMHIIBIA_02332 1.5e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
DMHIIBIA_02333 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
DMHIIBIA_02335 1.61e-130 - - - P - - - Probably functions as a manganese efflux pump
DMHIIBIA_02336 6.65e-145 - - - K - - - Protein of unknown function (DUF1232)
DMHIIBIA_02338 5.59e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
DMHIIBIA_02341 2.78e-272 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMHIIBIA_02342 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
DMHIIBIA_02343 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
DMHIIBIA_02344 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
DMHIIBIA_02345 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
DMHIIBIA_02346 8.39e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
DMHIIBIA_02347 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMHIIBIA_02348 6.4e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DMHIIBIA_02349 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DMHIIBIA_02350 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DMHIIBIA_02351 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMHIIBIA_02352 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMHIIBIA_02353 1.36e-87 yqhY - - S - - - protein conserved in bacteria
DMHIIBIA_02354 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DMHIIBIA_02355 1.63e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DMHIIBIA_02356 3.89e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
DMHIIBIA_02357 9.57e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
DMHIIBIA_02358 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
DMHIIBIA_02359 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
DMHIIBIA_02360 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
DMHIIBIA_02361 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
DMHIIBIA_02362 9.44e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
DMHIIBIA_02363 2.56e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
DMHIIBIA_02364 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
DMHIIBIA_02365 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMHIIBIA_02366 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
DMHIIBIA_02367 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
DMHIIBIA_02368 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
DMHIIBIA_02369 1.54e-82 yqhP - - - - - - -
DMHIIBIA_02370 2.85e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
DMHIIBIA_02371 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
DMHIIBIA_02372 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
DMHIIBIA_02373 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
DMHIIBIA_02374 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMHIIBIA_02375 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMHIIBIA_02376 3.18e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
DMHIIBIA_02377 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
DMHIIBIA_02378 6.18e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
DMHIIBIA_02379 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
DMHIIBIA_02380 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
DMHIIBIA_02381 6.08e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
DMHIIBIA_02382 7.34e-100 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
DMHIIBIA_02383 2.7e-155 yqxM - - - ko:K19433 - ko00000 -
DMHIIBIA_02384 1.14e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
DMHIIBIA_02385 2e-36 yqzE - - S - - - YqzE-like protein
DMHIIBIA_02386 5.5e-80 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
DMHIIBIA_02387 1.82e-84 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
DMHIIBIA_02388 2.21e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
DMHIIBIA_02389 5.36e-92 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
DMHIIBIA_02390 2.41e-55 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
DMHIIBIA_02391 4.65e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
DMHIIBIA_02392 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMHIIBIA_02393 2.62e-238 yqxL - - P - - - Mg2 transporter protein
DMHIIBIA_02394 7.58e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DMHIIBIA_02395 1.68e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DMHIIBIA_02397 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
DMHIIBIA_02398 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
DMHIIBIA_02399 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
DMHIIBIA_02400 4.36e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
DMHIIBIA_02401 3.5e-64 dglA - - S - - - Thiamine-binding protein
DMHIIBIA_02402 2.11e-253 yqgU - - - - - - -
DMHIIBIA_02403 5.21e-277 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
DMHIIBIA_02404 2.05e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
DMHIIBIA_02405 4.21e-275 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
DMHIIBIA_02406 3.79e-11 yqgO - - - - - - -
DMHIIBIA_02407 1.01e-124 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMHIIBIA_02408 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
DMHIIBIA_02409 3.42e-68 yqzD - - - - - - -
DMHIIBIA_02410 1.02e-98 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DMHIIBIA_02411 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DMHIIBIA_02412 6.56e-183 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DMHIIBIA_02413 3.26e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
DMHIIBIA_02414 2.48e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
DMHIIBIA_02415 9.5e-208 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
DMHIIBIA_02416 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
DMHIIBIA_02417 9.63e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
DMHIIBIA_02418 1.72e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
DMHIIBIA_02419 2.27e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
DMHIIBIA_02420 2.44e-164 yqgB - - S - - - Protein of unknown function (DUF1189)
DMHIIBIA_02421 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
DMHIIBIA_02422 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMHIIBIA_02423 3.34e-80 yqfX - - S - - - membrane
DMHIIBIA_02424 1.67e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
DMHIIBIA_02425 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
DMHIIBIA_02426 1.05e-196 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_02427 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
DMHIIBIA_02428 7.01e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMHIIBIA_02429 1.05e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DMHIIBIA_02430 8.3e-84 yqfQ - - S - - - YqfQ-like protein
DMHIIBIA_02431 3.38e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMHIIBIA_02432 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMHIIBIA_02433 1.72e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
DMHIIBIA_02434 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
DMHIIBIA_02435 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DMHIIBIA_02436 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DMHIIBIA_02437 2.74e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
DMHIIBIA_02438 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DMHIIBIA_02439 5.89e-145 ccpN - - K - - - CBS domain
DMHIIBIA_02440 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
DMHIIBIA_02441 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
DMHIIBIA_02442 2.06e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
DMHIIBIA_02443 6e-24 - - - S - - - YqzL-like protein
DMHIIBIA_02444 8.2e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMHIIBIA_02445 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DMHIIBIA_02446 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
DMHIIBIA_02447 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMHIIBIA_02448 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
DMHIIBIA_02449 7.08e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
DMHIIBIA_02450 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
DMHIIBIA_02451 3.57e-61 yqfC - - S - - - sporulation protein YqfC
DMHIIBIA_02452 3.47e-83 yqfB - - - - - - -
DMHIIBIA_02453 1.3e-174 yqfA - - S - - - UPF0365 protein
DMHIIBIA_02454 2.21e-294 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
DMHIIBIA_02455 6.44e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
DMHIIBIA_02456 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
DMHIIBIA_02457 2.65e-199 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
DMHIIBIA_02458 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
DMHIIBIA_02459 1.44e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DMHIIBIA_02460 6.31e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
DMHIIBIA_02461 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DMHIIBIA_02462 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
DMHIIBIA_02463 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMHIIBIA_02464 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DMHIIBIA_02465 1.96e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
DMHIIBIA_02466 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DMHIIBIA_02467 3.5e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
DMHIIBIA_02468 1.51e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
DMHIIBIA_02469 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DMHIIBIA_02470 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
DMHIIBIA_02471 7.42e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
DMHIIBIA_02472 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
DMHIIBIA_02473 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
DMHIIBIA_02474 2.81e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
DMHIIBIA_02475 4.85e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMHIIBIA_02476 1.63e-176 yqeM - - Q - - - Methyltransferase
DMHIIBIA_02477 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DMHIIBIA_02478 2.29e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
DMHIIBIA_02479 1.13e-137 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMHIIBIA_02480 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
DMHIIBIA_02481 2.95e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMHIIBIA_02482 4.59e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DMHIIBIA_02483 3.19e-122 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
DMHIIBIA_02485 6.95e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
DMHIIBIA_02486 7.77e-179 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
DMHIIBIA_02487 2.3e-135 yqeD - - S - - - SNARE associated Golgi protein
DMHIIBIA_02488 5.3e-269 - - - EGP - - - Transmembrane secretion effector
DMHIIBIA_02489 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMHIIBIA_02490 2.16e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
DMHIIBIA_02491 5.47e-120 - - - K - - - Transcriptional regulator PadR-like family
DMHIIBIA_02492 6.5e-188 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
DMHIIBIA_02494 5.27e-126 yqaC - - F - - - adenylate kinase activity
DMHIIBIA_02495 8.07e-30 - - - K - - - acetyltransferase
DMHIIBIA_02496 1.87e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_02497 2.28e-102 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
DMHIIBIA_02498 4.76e-121 - - - S - - - DinB family
DMHIIBIA_02499 9.38e-187 supH - - S - - - hydrolase
DMHIIBIA_02500 7.99e-185 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
DMHIIBIA_02501 1.18e-167 - - - K - - - Helix-turn-helix domain, rpiR family
DMHIIBIA_02502 1.06e-232 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DMHIIBIA_02503 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_02504 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
DMHIIBIA_02505 4.05e-230 romA - - S - - - Beta-lactamase superfamily domain
DMHIIBIA_02506 1.27e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMHIIBIA_02507 4.38e-210 yybE - - K - - - Transcriptional regulator
DMHIIBIA_02508 1.53e-269 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_02509 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
DMHIIBIA_02510 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
DMHIIBIA_02511 2.12e-119 yrhH - - Q - - - methyltransferase
DMHIIBIA_02512 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
DMHIIBIA_02513 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
DMHIIBIA_02514 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
DMHIIBIA_02515 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
DMHIIBIA_02516 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
DMHIIBIA_02517 5.51e-46 yrhC - - S - - - YrhC-like protein
DMHIIBIA_02518 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DMHIIBIA_02519 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
DMHIIBIA_02520 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMHIIBIA_02521 1.35e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
DMHIIBIA_02522 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
DMHIIBIA_02523 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
DMHIIBIA_02524 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
DMHIIBIA_02525 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DMHIIBIA_02526 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
DMHIIBIA_02527 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
DMHIIBIA_02528 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
DMHIIBIA_02529 2.22e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
DMHIIBIA_02530 2.7e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DMHIIBIA_02531 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
DMHIIBIA_02532 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMHIIBIA_02533 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
DMHIIBIA_02534 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMHIIBIA_02535 1.56e-235 yrrI - - S - - - AI-2E family transporter
DMHIIBIA_02536 3.66e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DMHIIBIA_02537 1.82e-188 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DMHIIBIA_02538 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DMHIIBIA_02539 3.1e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DMHIIBIA_02540 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
DMHIIBIA_02541 8.4e-42 yrzR - - - - - - -
DMHIIBIA_02542 1.69e-105 yrrD - - S - - - protein conserved in bacteria
DMHIIBIA_02543 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DMHIIBIA_02544 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
DMHIIBIA_02545 5.04e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DMHIIBIA_02546 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DMHIIBIA_02547 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_02548 3.07e-302 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
DMHIIBIA_02549 1.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
DMHIIBIA_02550 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMHIIBIA_02551 1e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
DMHIIBIA_02554 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
DMHIIBIA_02555 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DMHIIBIA_02556 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMHIIBIA_02557 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DMHIIBIA_02558 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
DMHIIBIA_02559 7.78e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
DMHIIBIA_02560 3.62e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
DMHIIBIA_02561 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMHIIBIA_02562 4.04e-67 yrzD - - S - - - Post-transcriptional regulator
DMHIIBIA_02563 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_02564 2.03e-143 yrbG - - S - - - membrane
DMHIIBIA_02565 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
DMHIIBIA_02566 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
DMHIIBIA_02567 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DMHIIBIA_02568 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMHIIBIA_02569 2.8e-28 yrzS - - S - - - Protein of unknown function (DUF2905)
DMHIIBIA_02570 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DMHIIBIA_02571 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DMHIIBIA_02572 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
DMHIIBIA_02574 1.91e-62 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DMHIIBIA_02575 1.65e-244 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
DMHIIBIA_02576 2.02e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMHIIBIA_02577 4.31e-195 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
DMHIIBIA_02578 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
DMHIIBIA_02579 1.83e-281 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DMHIIBIA_02580 9.72e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
DMHIIBIA_02581 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
DMHIIBIA_02582 1.2e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
DMHIIBIA_02583 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMHIIBIA_02584 3.5e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
DMHIIBIA_02585 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
DMHIIBIA_02586 4.07e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
DMHIIBIA_02587 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
DMHIIBIA_02588 4.89e-204 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
DMHIIBIA_02589 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
DMHIIBIA_02590 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
DMHIIBIA_02591 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DMHIIBIA_02592 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
DMHIIBIA_02593 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
DMHIIBIA_02594 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
DMHIIBIA_02595 7.15e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
DMHIIBIA_02596 1.53e-126 maf - - D ko:K06287 - ko00000 septum formation protein Maf
DMHIIBIA_02597 1.41e-205 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
DMHIIBIA_02598 4.26e-170 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
DMHIIBIA_02599 2.97e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
DMHIIBIA_02600 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DMHIIBIA_02601 1.53e-35 - - - - - - - -
DMHIIBIA_02602 3.66e-249 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DMHIIBIA_02603 6.17e-300 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
DMHIIBIA_02604 4.63e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
DMHIIBIA_02605 1.02e-235 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
DMHIIBIA_02606 1.89e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
DMHIIBIA_02607 1.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DMHIIBIA_02608 2.67e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
DMHIIBIA_02609 1.24e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMHIIBIA_02610 3.93e-114 ysxD - - - - - - -
DMHIIBIA_02611 3.1e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
DMHIIBIA_02612 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DMHIIBIA_02613 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
DMHIIBIA_02614 3.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMHIIBIA_02615 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DMHIIBIA_02616 1.3e-238 ysoA - - H - - - Tetratricopeptide repeat
DMHIIBIA_02617 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMHIIBIA_02618 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMHIIBIA_02619 7.12e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DMHIIBIA_02620 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMHIIBIA_02621 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMHIIBIA_02622 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
DMHIIBIA_02623 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
DMHIIBIA_02628 6.72e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
DMHIIBIA_02629 1.85e-130 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMHIIBIA_02630 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DMHIIBIA_02631 2.58e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
DMHIIBIA_02632 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
DMHIIBIA_02633 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
DMHIIBIA_02634 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_02635 1.8e-99 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
DMHIIBIA_02636 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
DMHIIBIA_02637 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
DMHIIBIA_02638 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
DMHIIBIA_02639 7.02e-103 yslB - - S - - - Protein of unknown function (DUF2507)
DMHIIBIA_02640 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DMHIIBIA_02641 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DMHIIBIA_02642 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
DMHIIBIA_02643 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
DMHIIBIA_02644 1.18e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
DMHIIBIA_02645 1.01e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
DMHIIBIA_02646 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
DMHIIBIA_02647 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_02648 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DMHIIBIA_02649 9.33e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
DMHIIBIA_02650 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
DMHIIBIA_02651 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DMHIIBIA_02652 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
DMHIIBIA_02653 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
DMHIIBIA_02654 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DMHIIBIA_02655 4.38e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMHIIBIA_02656 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DMHIIBIA_02657 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DMHIIBIA_02658 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMHIIBIA_02659 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
DMHIIBIA_02660 2.81e-258 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
DMHIIBIA_02661 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
DMHIIBIA_02662 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
DMHIIBIA_02663 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
DMHIIBIA_02664 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
DMHIIBIA_02665 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
DMHIIBIA_02666 1.78e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
DMHIIBIA_02667 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
DMHIIBIA_02668 5.51e-284 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
DMHIIBIA_02669 8.41e-179 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
DMHIIBIA_02670 4.01e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
DMHIIBIA_02671 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
DMHIIBIA_02672 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
DMHIIBIA_02673 1.64e-239 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
DMHIIBIA_02674 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
DMHIIBIA_02675 3.13e-86 ysdB - - S - - - Sigma-w pathway protein YsdB
DMHIIBIA_02676 5.44e-56 ysdA - - S - - - Membrane
DMHIIBIA_02677 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMHIIBIA_02678 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
DMHIIBIA_02679 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMHIIBIA_02680 2.09e-145 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DMHIIBIA_02681 7.85e-67 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
DMHIIBIA_02682 8.61e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
DMHIIBIA_02683 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_02684 9.84e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
DMHIIBIA_02685 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMHIIBIA_02686 1.63e-196 ytxC - - S - - - YtxC-like family
DMHIIBIA_02687 4.27e-138 ytxB - - S - - - SNARE associated Golgi protein
DMHIIBIA_02688 4.08e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
DMHIIBIA_02689 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
DMHIIBIA_02690 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMHIIBIA_02691 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DMHIIBIA_02692 1.27e-248 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DMHIIBIA_02693 1.69e-89 ytcD - - K - - - Transcriptional regulator
DMHIIBIA_02694 6.86e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
DMHIIBIA_02695 4.54e-205 ytbE - - S - - - reductase
DMHIIBIA_02696 5.93e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DMHIIBIA_02697 5.73e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
DMHIIBIA_02698 4.02e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DMHIIBIA_02699 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMHIIBIA_02700 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
DMHIIBIA_02701 2.9e-167 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_02702 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
DMHIIBIA_02703 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
DMHIIBIA_02704 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DMHIIBIA_02705 3.72e-81 yjdF3 - - S - - - Protein of unknown function (DUF2992)
DMHIIBIA_02706 5.65e-96 ytwI - - S - - - membrane
DMHIIBIA_02707 3.33e-246 ytvI - - S - - - sporulation integral membrane protein YtvI
DMHIIBIA_02708 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
DMHIIBIA_02709 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
DMHIIBIA_02710 1.14e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DMHIIBIA_02711 1.34e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DMHIIBIA_02712 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DMHIIBIA_02713 2.45e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
DMHIIBIA_02714 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
DMHIIBIA_02715 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
DMHIIBIA_02716 4.38e-113 ytrI - - - - - - -
DMHIIBIA_02717 1e-31 - - - - - - - -
DMHIIBIA_02718 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
DMHIIBIA_02719 3.57e-62 ytpI - - S - - - YtpI-like protein
DMHIIBIA_02720 1.31e-302 ytoI - - K - - - transcriptional regulator containing CBS domains
DMHIIBIA_02721 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
DMHIIBIA_02722 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_02724 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
DMHIIBIA_02725 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
DMHIIBIA_02726 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
DMHIIBIA_02727 1.57e-279 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMHIIBIA_02728 1.32e-227 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
DMHIIBIA_02729 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DMHIIBIA_02730 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
DMHIIBIA_02731 1.26e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
DMHIIBIA_02732 2.77e-114 yteJ - - S - - - RDD family
DMHIIBIA_02733 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
DMHIIBIA_02734 3.16e-194 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMHIIBIA_02735 0.0 ytcJ - - S - - - amidohydrolase
DMHIIBIA_02736 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DMHIIBIA_02737 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
DMHIIBIA_02738 4.05e-285 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DMHIIBIA_02739 3.73e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DMHIIBIA_02740 1.04e-303 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
DMHIIBIA_02741 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DMHIIBIA_02742 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
DMHIIBIA_02743 1.98e-140 yttP - - K - - - Transcriptional regulator
DMHIIBIA_02744 2.48e-111 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
DMHIIBIA_02745 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
DMHIIBIA_02746 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMHIIBIA_02747 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DMHIIBIA_02748 4.11e-129 yokH - - G - - - SMI1 / KNR4 family
DMHIIBIA_02749 2.51e-281 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMHIIBIA_02751 1.93e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
DMHIIBIA_02753 5.41e-173 - - - E - - - GDSL-like Lipase/Acylhydrolase family
DMHIIBIA_02754 1.95e-190 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMHIIBIA_02755 1.06e-188 - - - K - - - Transcriptional regulator
DMHIIBIA_02756 9.98e-161 ygaZ - - E - - - AzlC protein
DMHIIBIA_02757 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
DMHIIBIA_02758 9.91e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMHIIBIA_02759 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DMHIIBIA_02760 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
DMHIIBIA_02761 1.19e-149 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
DMHIIBIA_02762 1.12e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
DMHIIBIA_02763 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
DMHIIBIA_02764 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
DMHIIBIA_02765 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
DMHIIBIA_02766 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
DMHIIBIA_02767 5.67e-56 ytxJ - - O - - - Protein of unknown function (DUF2847)
DMHIIBIA_02768 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
DMHIIBIA_02769 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DMHIIBIA_02770 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
DMHIIBIA_02771 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DMHIIBIA_02772 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DMHIIBIA_02773 1.97e-189 ytpQ - - S - - - Belongs to the UPF0354 family
DMHIIBIA_02774 5.47e-76 ytpP - - CO - - - Thioredoxin
DMHIIBIA_02775 3.91e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
DMHIIBIA_02776 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
DMHIIBIA_02777 9.96e-69 ytzB - - S - - - small secreted protein
DMHIIBIA_02778 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
DMHIIBIA_02779 5.12e-207 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DMHIIBIA_02780 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DMHIIBIA_02781 3.88e-60 ytzH - - S - - - YtzH-like protein
DMHIIBIA_02782 2.93e-199 ytmP - - M - - - Phosphotransferase
DMHIIBIA_02783 3.25e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
DMHIIBIA_02784 3.58e-212 ytlQ - - - - - - -
DMHIIBIA_02785 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DMHIIBIA_02786 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DMHIIBIA_02787 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
DMHIIBIA_02788 1.42e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
DMHIIBIA_02789 3.53e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
DMHIIBIA_02790 1.56e-164 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
DMHIIBIA_02791 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
DMHIIBIA_02792 3.53e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DMHIIBIA_02793 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_02794 5.3e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
DMHIIBIA_02795 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
DMHIIBIA_02796 2.14e-36 yteV - - S - - - Sporulation protein Cse60
DMHIIBIA_02797 1.84e-237 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_02798 3.79e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
DMHIIBIA_02799 5.58e-218 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DMHIIBIA_02800 4.1e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
DMHIIBIA_02801 9.62e-317 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
DMHIIBIA_02802 1.98e-110 - - - M - - - Acetyltransferase (GNAT) domain
DMHIIBIA_02803 6.05e-69 ytwF - - P - - - Sulfurtransferase
DMHIIBIA_02804 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
DMHIIBIA_02805 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
DMHIIBIA_02806 1.32e-174 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
DMHIIBIA_02807 6.76e-269 yttB - - EGP - - - Major facilitator superfamily
DMHIIBIA_02808 1.47e-157 ywaF - - S - - - Integral membrane protein
DMHIIBIA_02809 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
DMHIIBIA_02810 3.81e-173 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_02811 8.05e-233 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
DMHIIBIA_02812 4.49e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_02813 3.9e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
DMHIIBIA_02814 3.01e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_02815 1.51e-199 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
DMHIIBIA_02816 8.02e-230 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DMHIIBIA_02817 6.39e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DMHIIBIA_02818 5.11e-208 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_02819 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
DMHIIBIA_02821 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
DMHIIBIA_02822 3.79e-248 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DMHIIBIA_02823 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_02824 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
DMHIIBIA_02825 2.1e-135 ytqB - - J - - - Putative rRNA methylase
DMHIIBIA_02827 7.09e-183 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
DMHIIBIA_02828 9.59e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
DMHIIBIA_02829 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
DMHIIBIA_02830 8.19e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DMHIIBIA_02831 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_02832 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
DMHIIBIA_02833 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMHIIBIA_02834 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DMHIIBIA_02835 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
DMHIIBIA_02836 7.79e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
DMHIIBIA_02837 1.25e-236 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
DMHIIBIA_02838 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DMHIIBIA_02839 7.52e-174 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DMHIIBIA_02840 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
DMHIIBIA_02841 3.51e-79 ytkC - - S - - - Bacteriophage holin family
DMHIIBIA_02842 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
DMHIIBIA_02844 1.66e-96 ytkA - - S - - - YtkA-like
DMHIIBIA_02845 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DMHIIBIA_02846 2.83e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
DMHIIBIA_02847 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
DMHIIBIA_02848 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
DMHIIBIA_02849 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
DMHIIBIA_02850 1.49e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
DMHIIBIA_02851 3.2e-33 - - - S - - - Domain of Unknown Function (DUF1540)
DMHIIBIA_02852 2.03e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DMHIIBIA_02853 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DMHIIBIA_02854 6.18e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DMHIIBIA_02855 3.43e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
DMHIIBIA_02856 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMHIIBIA_02857 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
DMHIIBIA_02858 2.04e-167 yteA - - T - - - COG1734 DnaK suppressor protein
DMHIIBIA_02859 2.13e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
DMHIIBIA_02883 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DMHIIBIA_02884 5.96e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
DMHIIBIA_02885 3.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
DMHIIBIA_02886 4.61e-108 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
DMHIIBIA_02887 1.66e-101 yuaE - - S - - - DinB superfamily
DMHIIBIA_02888 6.79e-141 - - - S - - - MOSC domain
DMHIIBIA_02889 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
DMHIIBIA_02890 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DMHIIBIA_02891 1.67e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
DMHIIBIA_02892 4.1e-122 yuaB - - - - - - -
DMHIIBIA_02893 1.76e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
DMHIIBIA_02894 6.07e-190 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DMHIIBIA_02895 5.28e-281 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMHIIBIA_02896 1.99e-152 - - - G - - - Cupin
DMHIIBIA_02897 6.45e-70 yjcN - - - - - - -
DMHIIBIA_02899 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DMHIIBIA_02900 2.85e-250 yubA - - S - - - transporter activity
DMHIIBIA_02901 1.35e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
DMHIIBIA_02902 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
DMHIIBIA_02903 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DMHIIBIA_02904 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DMHIIBIA_02905 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DMHIIBIA_02906 4.4e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DMHIIBIA_02907 6.36e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
DMHIIBIA_02908 9.36e-55 - - - - - - - -
DMHIIBIA_02909 5.75e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
DMHIIBIA_02910 8.68e-95 yugU - - S - - - Uncharacterised protein family UPF0047
DMHIIBIA_02911 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
DMHIIBIA_02912 7.73e-295 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DMHIIBIA_02913 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
DMHIIBIA_02914 3.06e-23 - - - - - - - -
DMHIIBIA_02915 3.47e-35 mstX - - S - - - Membrane-integrating protein Mistic
DMHIIBIA_02916 3.41e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
DMHIIBIA_02917 1.17e-92 yugN - - S - - - YugN-like family
DMHIIBIA_02919 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
DMHIIBIA_02920 1.04e-128 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
DMHIIBIA_02921 8.75e-152 ycaC - - Q - - - Isochorismatase family
DMHIIBIA_02922 6.49e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
DMHIIBIA_02923 3.19e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
DMHIIBIA_02924 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
DMHIIBIA_02925 1.43e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
DMHIIBIA_02926 6.82e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
DMHIIBIA_02927 3.75e-109 alaR - - K - - - Transcriptional regulator
DMHIIBIA_02928 4.71e-199 yugF - - I - - - Hydrolase
DMHIIBIA_02929 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
DMHIIBIA_02930 1.3e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DMHIIBIA_02931 8.61e-291 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_02932 3.28e-87 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
DMHIIBIA_02933 2.64e-153 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
DMHIIBIA_02934 1.84e-263 yuxJ - - EGP - - - Major facilitator superfamily
DMHIIBIA_02935 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
DMHIIBIA_02936 2.62e-95 yuxK - - S - - - protein conserved in bacteria
DMHIIBIA_02937 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
DMHIIBIA_02938 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DMHIIBIA_02939 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
DMHIIBIA_02940 1.94e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
DMHIIBIA_02941 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_02942 3.86e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DMHIIBIA_02943 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DMHIIBIA_02945 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DMHIIBIA_02946 1.27e-89 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DMHIIBIA_02947 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DMHIIBIA_02948 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DMHIIBIA_02949 9.67e-99 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DMHIIBIA_02950 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DMHIIBIA_02951 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
DMHIIBIA_02952 9.44e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
DMHIIBIA_02953 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_02954 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_02956 7.34e-124 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
DMHIIBIA_02957 2.66e-11 - - - S - - - DegQ (SacQ) family
DMHIIBIA_02959 6.01e-67 yuzC - - - - - - -
DMHIIBIA_02960 6.32e-294 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
DMHIIBIA_02961 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DMHIIBIA_02962 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
DMHIIBIA_02963 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
DMHIIBIA_02964 5.46e-51 yueH - - S - - - YueH-like protein
DMHIIBIA_02965 9e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
DMHIIBIA_02966 1.54e-237 yueF - - S - - - transporter activity
DMHIIBIA_02967 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
DMHIIBIA_02968 2.23e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
DMHIIBIA_02969 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_02970 1.09e-99 yueC - - S - - - Family of unknown function (DUF5383)
DMHIIBIA_02971 0.0 yueB - - S - - - type VII secretion protein EsaA
DMHIIBIA_02972 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
DMHIIBIA_02973 4.2e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
DMHIIBIA_02974 9.1e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
DMHIIBIA_02975 2.36e-61 yukE - - S - - - Belongs to the WXG100 family
DMHIIBIA_02976 2.11e-291 yukF - - QT - - - Transcriptional regulator
DMHIIBIA_02977 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
DMHIIBIA_02978 1.7e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
DMHIIBIA_02979 2.24e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
DMHIIBIA_02980 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_02981 1.87e-218 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
DMHIIBIA_02982 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
DMHIIBIA_02983 9.41e-278 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
DMHIIBIA_02984 2.27e-167 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_02985 2.85e-208 eSD - - S ko:K07017 - ko00000 Putative esterase
DMHIIBIA_02986 4.59e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
DMHIIBIA_02987 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
DMHIIBIA_02988 2.35e-275 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
DMHIIBIA_02989 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DMHIIBIA_02990 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
DMHIIBIA_02991 2.42e-153 yuiC - - S - - - protein conserved in bacteria
DMHIIBIA_02992 8.54e-46 yuiB - - S - - - Putative membrane protein
DMHIIBIA_02993 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DMHIIBIA_02994 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
DMHIIBIA_02996 7.47e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DMHIIBIA_02997 5.68e-40 - - - - - - - -
DMHIIBIA_02998 3.42e-92 - - - CP - - - Membrane
DMHIIBIA_02999 1.08e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
DMHIIBIA_03001 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
DMHIIBIA_03003 2.89e-36 - - - K - - - helix_turn_helix, mercury resistance
DMHIIBIA_03004 1.05e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_03005 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
DMHIIBIA_03006 2.63e-206 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMHIIBIA_03007 4.26e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DMHIIBIA_03008 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
DMHIIBIA_03009 1.71e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DMHIIBIA_03010 4.5e-71 yuzD - - S - - - protein conserved in bacteria
DMHIIBIA_03011 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
DMHIIBIA_03012 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
DMHIIBIA_03013 1.12e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DMHIIBIA_03014 2.3e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMHIIBIA_03015 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
DMHIIBIA_03016 4.25e-248 yutH - - S - - - Spore coat protein
DMHIIBIA_03017 8.66e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
DMHIIBIA_03018 4.13e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DMHIIBIA_03019 3e-93 yutE - - S - - - Protein of unknown function DUF86
DMHIIBIA_03020 3.71e-62 yutD - - S - - - protein conserved in bacteria
DMHIIBIA_03021 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMHIIBIA_03022 2.36e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
DMHIIBIA_03023 7.89e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
DMHIIBIA_03024 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
DMHIIBIA_03025 4.99e-185 yunE - - S ko:K07090 - ko00000 membrane transporter protein
DMHIIBIA_03026 8.57e-216 yunF - - S - - - Protein of unknown function DUF72
DMHIIBIA_03027 4.16e-78 - - - S - - - phosphoglycolate phosphatase activity
DMHIIBIA_03028 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
DMHIIBIA_03029 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
DMHIIBIA_03030 1.61e-26 - - - - - - - -
DMHIIBIA_03032 3.51e-273 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_03033 9.45e-299 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
DMHIIBIA_03034 5.44e-296 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
DMHIIBIA_03035 5.35e-213 bsn - - L - - - Ribonuclease
DMHIIBIA_03036 1.07e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_03037 2.4e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
DMHIIBIA_03038 7.24e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
DMHIIBIA_03039 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
DMHIIBIA_03040 1.51e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DMHIIBIA_03041 1.49e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
DMHIIBIA_03042 1.35e-237 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
DMHIIBIA_03043 2.24e-210 - - - K - - - helix_turn_helix, mercury resistance
DMHIIBIA_03045 3.33e-85 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
DMHIIBIA_03046 1.44e-256 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
DMHIIBIA_03047 8.53e-163 - - - Q - - - ubiE/COQ5 methyltransferase family
DMHIIBIA_03048 1.55e-83 yncE - - S - - - Protein of unknown function (DUF2691)
DMHIIBIA_03049 3.07e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
DMHIIBIA_03050 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
DMHIIBIA_03051 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
DMHIIBIA_03052 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMHIIBIA_03053 5.01e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
DMHIIBIA_03054 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DMHIIBIA_03055 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMHIIBIA_03056 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
DMHIIBIA_03057 2.08e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
DMHIIBIA_03058 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMHIIBIA_03059 5.28e-76 yusD - - S - - - SCP-2 sterol transfer family
DMHIIBIA_03060 1.64e-72 yusE - - CO - - - Thioredoxin
DMHIIBIA_03061 2.17e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
DMHIIBIA_03062 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
DMHIIBIA_03063 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
DMHIIBIA_03064 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
DMHIIBIA_03065 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
DMHIIBIA_03066 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
DMHIIBIA_03067 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
DMHIIBIA_03068 4.21e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
DMHIIBIA_03069 6.38e-263 yusP - - P - - - Major facilitator superfamily
DMHIIBIA_03070 4.55e-58 - - - - - - - -
DMHIIBIA_03071 4.46e-72 yusN - - M - - - Coat F domain
DMHIIBIA_03072 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
DMHIIBIA_03073 0.0 yusP - - P - - - Major facilitator superfamily
DMHIIBIA_03074 5.44e-200 - - - K - - - Transcriptional regulator
DMHIIBIA_03075 5.88e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
DMHIIBIA_03076 2.6e-235 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMHIIBIA_03077 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
DMHIIBIA_03078 5.24e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DMHIIBIA_03079 7.61e-60 - - - S - - - YusW-like protein
DMHIIBIA_03080 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
DMHIIBIA_03081 5.87e-192 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_03082 8.32e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
DMHIIBIA_03083 4.4e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMHIIBIA_03084 2.61e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03085 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_03086 4.63e-33 - - - - - - - -
DMHIIBIA_03087 2.09e-199 yuxN - - K - - - Transcriptional regulator
DMHIIBIA_03088 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DMHIIBIA_03089 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
DMHIIBIA_03090 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
DMHIIBIA_03091 2.07e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
DMHIIBIA_03092 1.07e-262 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
DMHIIBIA_03093 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_03094 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_03095 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
DMHIIBIA_03096 1.4e-183 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
DMHIIBIA_03097 3.63e-129 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
DMHIIBIA_03098 2.21e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
DMHIIBIA_03099 2.27e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_03100 1.26e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
DMHIIBIA_03101 1.76e-278 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
DMHIIBIA_03102 1.95e-226 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_03103 1.58e-213 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DMHIIBIA_03104 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_03105 3.11e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
DMHIIBIA_03106 0.0 yvrG - - T - - - Histidine kinase
DMHIIBIA_03107 1.56e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03108 1.38e-49 - - - - - - - -
DMHIIBIA_03109 1.31e-133 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
DMHIIBIA_03110 1.88e-21 - - - S - - - YvrJ protein family
DMHIIBIA_03111 7.32e-294 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
DMHIIBIA_03112 8.03e-87 yvrL - - S - - - Regulatory protein YrvL
DMHIIBIA_03113 1.02e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DMHIIBIA_03114 1.86e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_03115 9.43e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_03116 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DMHIIBIA_03117 6.84e-157 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DMHIIBIA_03118 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
DMHIIBIA_03119 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
DMHIIBIA_03120 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
DMHIIBIA_03121 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
DMHIIBIA_03122 4.72e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
DMHIIBIA_03123 1.13e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
DMHIIBIA_03124 1.57e-122 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
DMHIIBIA_03125 8.82e-146 yfiK - - K - - - Regulator
DMHIIBIA_03126 4.77e-250 - - - T - - - Histidine kinase
DMHIIBIA_03127 8.23e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
DMHIIBIA_03128 1.12e-245 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
DMHIIBIA_03129 1.49e-254 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
DMHIIBIA_03130 1.77e-200 yvgN - - S - - - reductase
DMHIIBIA_03131 1.32e-111 yvgO - - - - - - -
DMHIIBIA_03132 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
DMHIIBIA_03133 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
DMHIIBIA_03134 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMHIIBIA_03135 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
DMHIIBIA_03136 2.48e-127 yvgT - - S - - - membrane
DMHIIBIA_03137 1.1e-189 - - - S - - - Metallo-peptidase family M12
DMHIIBIA_03138 2.06e-93 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
DMHIIBIA_03139 7.83e-139 bdbD - - O - - - Thioredoxin
DMHIIBIA_03140 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
DMHIIBIA_03141 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
DMHIIBIA_03142 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
DMHIIBIA_03143 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
DMHIIBIA_03144 1.86e-244 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
DMHIIBIA_03145 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMHIIBIA_03146 5.5e-203 - - - K - - - Helix-turn-helix XRE-family like proteins
DMHIIBIA_03147 1.62e-277 - - - EGP - - - Major Facilitator Superfamily
DMHIIBIA_03148 5.69e-86 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
DMHIIBIA_03149 1.82e-181 - - - S ko:K07045 - ko00000 Amidohydrolase
DMHIIBIA_03150 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_03151 4.12e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
DMHIIBIA_03152 4.31e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_03153 1.23e-178 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DMHIIBIA_03154 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DMHIIBIA_03155 2e-154 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DMHIIBIA_03156 3.54e-188 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
DMHIIBIA_03157 3.98e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
DMHIIBIA_03158 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
DMHIIBIA_03159 3.41e-207 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
DMHIIBIA_03160 9.27e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DMHIIBIA_03161 1.63e-63 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
DMHIIBIA_03163 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMHIIBIA_03164 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DMHIIBIA_03165 5.69e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
DMHIIBIA_03166 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
DMHIIBIA_03167 1.64e-47 yvzC - - K - - - transcriptional
DMHIIBIA_03168 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
DMHIIBIA_03169 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
DMHIIBIA_03170 2.97e-70 yvaP - - K - - - transcriptional
DMHIIBIA_03171 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
DMHIIBIA_03172 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
DMHIIBIA_03173 1.22e-172 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DMHIIBIA_03174 5.97e-158 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DMHIIBIA_03175 2.67e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_03176 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DMHIIBIA_03177 7.34e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DMHIIBIA_03178 1.14e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DMHIIBIA_03179 8.79e-263 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DMHIIBIA_03180 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
DMHIIBIA_03181 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DMHIIBIA_03182 6.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DMHIIBIA_03183 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DMHIIBIA_03184 2.1e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DMHIIBIA_03185 2.38e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
DMHIIBIA_03186 4.44e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
DMHIIBIA_03187 8.89e-156 yvbI - - M - - - Membrane
DMHIIBIA_03188 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
DMHIIBIA_03189 1.29e-105 yvbK - - K - - - acetyltransferase
DMHIIBIA_03190 1.73e-266 - - - EGP - - - Major facilitator Superfamily
DMHIIBIA_03191 2.21e-225 - - - - - - - -
DMHIIBIA_03192 8.69e-160 - - - S - - - GlcNAc-PI de-N-acetylase
DMHIIBIA_03193 3.94e-183 - - - C - - - WbqC-like protein family
DMHIIBIA_03194 1.64e-184 - - - M - - - Protein involved in cellulose biosynthesis
DMHIIBIA_03195 3.21e-286 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMHIIBIA_03196 5.79e-218 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
DMHIIBIA_03197 3.81e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
DMHIIBIA_03198 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMHIIBIA_03199 3.29e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
DMHIIBIA_03200 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DMHIIBIA_03201 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
DMHIIBIA_03202 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DMHIIBIA_03203 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
DMHIIBIA_03204 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DMHIIBIA_03205 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DMHIIBIA_03207 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMHIIBIA_03208 1.57e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
DMHIIBIA_03209 3.08e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_03211 4.32e-200 yvbU - - K - - - Transcriptional regulator
DMHIIBIA_03212 5.22e-203 yvbV - - EG - - - EamA-like transporter family
DMHIIBIA_03213 9.5e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_03215 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
DMHIIBIA_03216 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
DMHIIBIA_03217 1.6e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
DMHIIBIA_03218 9.73e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DMHIIBIA_03219 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
DMHIIBIA_03220 2.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DMHIIBIA_03221 1.9e-276 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DMHIIBIA_03222 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
DMHIIBIA_03223 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
DMHIIBIA_03224 1.09e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
DMHIIBIA_03225 4.01e-44 yvfG - - S - - - YvfG protein
DMHIIBIA_03226 2.24e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
DMHIIBIA_03227 9.1e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
DMHIIBIA_03228 2.23e-71 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
DMHIIBIA_03229 1.58e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DMHIIBIA_03230 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_03231 5.18e-250 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DMHIIBIA_03232 2.71e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
DMHIIBIA_03233 1.8e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
DMHIIBIA_03234 6.95e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
DMHIIBIA_03235 4.77e-270 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
DMHIIBIA_03236 4.54e-205 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
DMHIIBIA_03237 1.18e-275 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
DMHIIBIA_03238 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
DMHIIBIA_03239 3.12e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
DMHIIBIA_03240 7.89e-154 epsA - - M ko:K19420 - ko00000 biosynthesis protein
DMHIIBIA_03241 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
DMHIIBIA_03242 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
DMHIIBIA_03244 1.91e-125 ywjB - - H - - - RibD C-terminal domain
DMHIIBIA_03245 1.06e-145 yyaS - - S ko:K07149 - ko00000 Membrane
DMHIIBIA_03246 7.44e-117 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DMHIIBIA_03247 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
DMHIIBIA_03249 3.28e-30 - - - S - - - Protein of unknown function (DUF1433)
DMHIIBIA_03250 3.97e-16 - - - S - - - Protein of unknown function (DUF1433)
DMHIIBIA_03251 0.0 - - - I - - - Pfam Lipase (class 3)
DMHIIBIA_03252 1.31e-45 - - - - - - - -
DMHIIBIA_03254 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
DMHIIBIA_03255 9.53e-284 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
DMHIIBIA_03256 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
DMHIIBIA_03257 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DMHIIBIA_03258 2.75e-209 yraN - - K - - - Transcriptional regulator
DMHIIBIA_03259 2.75e-268 yraM - - S - - - PrpF protein
DMHIIBIA_03260 0.0 - - - EGP - - - Sugar (and other) transporter
DMHIIBIA_03262 2.19e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
DMHIIBIA_03263 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
DMHIIBIA_03264 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
DMHIIBIA_03265 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
DMHIIBIA_03266 2.81e-231 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMHIIBIA_03267 3.66e-103 - - - M - - - Ribonuclease
DMHIIBIA_03268 1.99e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
DMHIIBIA_03269 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
DMHIIBIA_03270 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
DMHIIBIA_03271 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
DMHIIBIA_03272 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
DMHIIBIA_03273 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
DMHIIBIA_03274 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DMHIIBIA_03275 3.05e-203 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
DMHIIBIA_03276 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
DMHIIBIA_03277 6.47e-244 sasA - - T - - - Histidine kinase
DMHIIBIA_03278 1.33e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03279 2.02e-70 - - - - - - - -
DMHIIBIA_03280 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
DMHIIBIA_03281 4.7e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
DMHIIBIA_03282 4.44e-173 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DMHIIBIA_03283 2.19e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMHIIBIA_03284 1.4e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMHIIBIA_03285 2.75e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
DMHIIBIA_03286 6.13e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMHIIBIA_03287 1.76e-146 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DMHIIBIA_03288 1.17e-267 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DMHIIBIA_03289 8.4e-177 yvpB - - NU - - - protein conserved in bacteria
DMHIIBIA_03290 5.93e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
DMHIIBIA_03291 1.57e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
DMHIIBIA_03292 4.15e-192 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMHIIBIA_03293 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMHIIBIA_03294 5.29e-283 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMHIIBIA_03295 2.22e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DMHIIBIA_03296 4.29e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
DMHIIBIA_03297 1.73e-133 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
DMHIIBIA_03298 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
DMHIIBIA_03299 6.3e-65 yvlD - - S ko:K08972 - ko00000 Membrane
DMHIIBIA_03300 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
DMHIIBIA_03301 9.16e-218 yvlB - - S - - - Putative adhesin
DMHIIBIA_03302 4.87e-66 yvlA - - - - - - -
DMHIIBIA_03303 8.07e-44 yvkN - - - - - - -
DMHIIBIA_03304 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DMHIIBIA_03305 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DMHIIBIA_03306 2.59e-45 csbA - - S - - - protein conserved in bacteria
DMHIIBIA_03307 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
DMHIIBIA_03308 7.78e-143 yvkB - - K - - - Transcriptional regulator
DMHIIBIA_03309 8.04e-296 yvkA - - P - - - -transporter
DMHIIBIA_03310 2.23e-233 - - - S - - - Psort location CytoplasmicMembrane, score
DMHIIBIA_03311 3.57e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMHIIBIA_03312 2.47e-73 swrA - - S - - - Swarming motility protein
DMHIIBIA_03313 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
DMHIIBIA_03314 1.64e-302 ywoF - - P - - - Right handed beta helix region
DMHIIBIA_03315 1.73e-195 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DMHIIBIA_03316 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
DMHIIBIA_03317 3.08e-60 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
DMHIIBIA_03318 6.56e-190 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_03319 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMHIIBIA_03320 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DMHIIBIA_03321 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMHIIBIA_03322 1.35e-89 - - - - - - - -
DMHIIBIA_03323 2.77e-11 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
DMHIIBIA_03324 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
DMHIIBIA_03325 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DMHIIBIA_03326 9.9e-153 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DMHIIBIA_03327 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DMHIIBIA_03328 2.48e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DMHIIBIA_03329 4.64e-107 yviE - - - - - - -
DMHIIBIA_03330 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
DMHIIBIA_03331 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
DMHIIBIA_03332 1.81e-104 yvyG - - NOU - - - FlgN protein
DMHIIBIA_03333 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
DMHIIBIA_03334 2.23e-97 yvyF - - S - - - flagellar protein
DMHIIBIA_03335 6.79e-98 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
DMHIIBIA_03336 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
DMHIIBIA_03337 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DMHIIBIA_03338 1.78e-203 degV - - S - - - protein conserved in bacteria
DMHIIBIA_03339 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_03340 1.4e-246 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
DMHIIBIA_03341 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
DMHIIBIA_03342 3.83e-230 yvhJ - - K - - - Transcriptional regulator
DMHIIBIA_03343 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
DMHIIBIA_03344 3.39e-296 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
DMHIIBIA_03345 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
DMHIIBIA_03346 9.6e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
DMHIIBIA_03347 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
DMHIIBIA_03348 1.57e-314 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMHIIBIA_03349 1.85e-284 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
DMHIIBIA_03350 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DMHIIBIA_03351 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DMHIIBIA_03352 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DMHIIBIA_03353 0.0 lytB - - D - - - Stage II sporulation protein
DMHIIBIA_03354 1.86e-64 - - - - - - - -
DMHIIBIA_03355 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
DMHIIBIA_03356 4.74e-266 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DMHIIBIA_03357 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
DMHIIBIA_03358 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DMHIIBIA_03359 5.06e-195 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
DMHIIBIA_03360 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DMHIIBIA_03361 0.0 - - - M - - - Glycosyltransferase like family 2
DMHIIBIA_03362 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
DMHIIBIA_03363 8.69e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DMHIIBIA_03364 1.68e-275 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DMHIIBIA_03365 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DMHIIBIA_03366 5.92e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DMHIIBIA_03367 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
DMHIIBIA_03368 4.98e-251 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
DMHIIBIA_03369 2.75e-268 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
DMHIIBIA_03370 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
DMHIIBIA_03371 8.17e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMHIIBIA_03372 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
DMHIIBIA_03373 1.77e-200 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
DMHIIBIA_03374 3.87e-68 yttA - - S - - - Pfam Transposase IS66
DMHIIBIA_03375 1.69e-298 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DMHIIBIA_03376 4.04e-29 ywtC - - - - - - -
DMHIIBIA_03377 6.62e-279 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
DMHIIBIA_03378 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
DMHIIBIA_03379 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
DMHIIBIA_03380 3.28e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
DMHIIBIA_03381 8.49e-245 - - - E - - - Spore germination protein
DMHIIBIA_03382 5.9e-259 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
DMHIIBIA_03383 2.47e-227 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
DMHIIBIA_03384 1.34e-199 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMHIIBIA_03385 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DMHIIBIA_03386 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
DMHIIBIA_03387 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DMHIIBIA_03388 8.09e-207 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
DMHIIBIA_03389 1.44e-116 batE - - T - - - Sh3 type 3 domain protein
DMHIIBIA_03390 4.13e-122 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
DMHIIBIA_03391 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
DMHIIBIA_03392 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
DMHIIBIA_03393 2.18e-214 alsR - - K - - - LysR substrate binding domain
DMHIIBIA_03395 4.73e-301 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DMHIIBIA_03396 4.87e-163 ywrJ - - - - - - -
DMHIIBIA_03397 6.63e-172 cotB - - - ko:K06325 - ko00000 -
DMHIIBIA_03398 6.5e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
DMHIIBIA_03399 3.39e-25 - - - - - - - -
DMHIIBIA_03400 5.72e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMHIIBIA_03402 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
DMHIIBIA_03403 1.01e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
DMHIIBIA_03404 6.69e-129 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
DMHIIBIA_03405 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
DMHIIBIA_03407 4.99e-119 ywqN - - S - - - NAD(P)H-dependent
DMHIIBIA_03408 1.39e-201 - - - K - - - Transcriptional regulator
DMHIIBIA_03409 6.6e-168 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
DMHIIBIA_03410 1.78e-18 - - - - - - - -
DMHIIBIA_03412 2.2e-191 ywqJ - - S - - - Pre-toxin TG
DMHIIBIA_03413 2.25e-54 - - - S - - - Protein of unknown function (DUF2004)
DMHIIBIA_03414 2.92e-66 - - - - - - - -
DMHIIBIA_03415 0.0 ywqJ - - S - - - Pre-toxin TG
DMHIIBIA_03416 2.97e-50 ywqI - - S - - - Family of unknown function (DUF5344)
DMHIIBIA_03418 7.76e-188 ywqG - - S - - - Domain of unknown function (DUF1963)
DMHIIBIA_03419 8.35e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMHIIBIA_03420 4.82e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
DMHIIBIA_03421 2.58e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
DMHIIBIA_03422 1.95e-149 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
DMHIIBIA_03423 1.74e-21 - - - - - - - -
DMHIIBIA_03424 0.0 ywqB - - S - - - SWIM zinc finger
DMHIIBIA_03425 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
DMHIIBIA_03426 2.93e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
DMHIIBIA_03427 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
DMHIIBIA_03428 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
DMHIIBIA_03429 4.49e-82 ywpG - - - - - - -
DMHIIBIA_03430 1.07e-89 ywpF - - S - - - YwpF-like protein
DMHIIBIA_03431 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DMHIIBIA_03432 1.28e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DMHIIBIA_03433 3.02e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
DMHIIBIA_03434 1.74e-183 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
DMHIIBIA_03435 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
DMHIIBIA_03436 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
DMHIIBIA_03437 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
DMHIIBIA_03438 7.23e-93 ywoH - - K - - - transcriptional
DMHIIBIA_03439 3.36e-271 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DMHIIBIA_03440 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
DMHIIBIA_03441 6.6e-311 ywoD - - EGP - - - Major facilitator superfamily
DMHIIBIA_03442 1.13e-132 yjgF - - Q - - - Isochorismatase family
DMHIIBIA_03443 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
DMHIIBIA_03444 1.29e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
DMHIIBIA_03445 9.52e-264 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DMHIIBIA_03446 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
DMHIIBIA_03447 5.45e-94 ywnJ - - S - - - VanZ like family
DMHIIBIA_03448 1.53e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
DMHIIBIA_03449 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
DMHIIBIA_03451 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
DMHIIBIA_03452 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMHIIBIA_03453 1.1e-76 ywnC - - S - - - Family of unknown function (DUF5362)
DMHIIBIA_03454 1.52e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
DMHIIBIA_03455 3.09e-88 ywnA - - K - - - Transcriptional regulator
DMHIIBIA_03456 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DMHIIBIA_03457 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
DMHIIBIA_03458 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
DMHIIBIA_03459 7.2e-18 csbD - - K - - - CsbD-like
DMHIIBIA_03460 5e-106 ywmF - - S - - - Peptidase M50
DMHIIBIA_03461 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
DMHIIBIA_03462 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMHIIBIA_03463 4.3e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMHIIBIA_03465 1.75e-157 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DMHIIBIA_03466 3.9e-146 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DMHIIBIA_03467 1.65e-241 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
DMHIIBIA_03468 4.75e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMHIIBIA_03469 3.4e-174 ywmB - - S - - - TATA-box binding
DMHIIBIA_03470 1.3e-44 ywzB - - S - - - membrane
DMHIIBIA_03471 6.9e-116 ywmA - - - - - - -
DMHIIBIA_03472 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
DMHIIBIA_03473 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMHIIBIA_03474 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMHIIBIA_03475 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMHIIBIA_03476 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMHIIBIA_03477 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMHIIBIA_03478 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMHIIBIA_03479 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
DMHIIBIA_03480 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
DMHIIBIA_03481 9.12e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DMHIIBIA_03482 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMHIIBIA_03483 3.02e-124 ywlG - - S - - - Belongs to the UPF0340 family
DMHIIBIA_03484 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
DMHIIBIA_03485 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMHIIBIA_03486 3.91e-118 mntP - - P - - - Probably functions as a manganese efflux pump
DMHIIBIA_03487 4.38e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DMHIIBIA_03488 1.72e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
DMHIIBIA_03489 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
DMHIIBIA_03490 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
DMHIIBIA_03492 6.39e-199 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DMHIIBIA_03493 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMHIIBIA_03494 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_03495 4.94e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
DMHIIBIA_03496 1.93e-200 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
DMHIIBIA_03497 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
DMHIIBIA_03498 6.76e-133 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
DMHIIBIA_03499 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
DMHIIBIA_03500 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMHIIBIA_03501 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
DMHIIBIA_03502 3.21e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMHIIBIA_03503 6.37e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMHIIBIA_03504 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
DMHIIBIA_03505 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
DMHIIBIA_03506 1.91e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
DMHIIBIA_03507 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DMHIIBIA_03508 2.79e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DMHIIBIA_03509 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
DMHIIBIA_03510 2.84e-284 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
DMHIIBIA_03511 1.29e-231 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
DMHIIBIA_03512 1.13e-58 ywjC - - - - - - -
DMHIIBIA_03513 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
DMHIIBIA_03514 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMHIIBIA_03515 2.89e-134 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMHIIBIA_03516 3.83e-155 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
DMHIIBIA_03517 2.1e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
DMHIIBIA_03518 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
DMHIIBIA_03519 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DMHIIBIA_03520 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
DMHIIBIA_03521 5.27e-179 ywiC - - S - - - YwiC-like protein
DMHIIBIA_03522 4.46e-166 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
DMHIIBIA_03523 1.66e-270 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
DMHIIBIA_03524 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
DMHIIBIA_03525 4.79e-57 ywiB - - S - - - protein conserved in bacteria
DMHIIBIA_03526 6.91e-104 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DMHIIBIA_03528 4.95e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
DMHIIBIA_03529 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DMHIIBIA_03530 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DMHIIBIA_03531 6.08e-106 - - - - - - - -
DMHIIBIA_03532 3.73e-121 ywhD - - S - - - YwhD family
DMHIIBIA_03533 3.84e-153 ywhC - - S - - - Peptidase family M50
DMHIIBIA_03534 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
DMHIIBIA_03535 9.43e-90 ywhA - - K - - - Transcriptional regulator
DMHIIBIA_03536 1.34e-313 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
DMHIIBIA_03537 8.24e-115 ywgA - - - ko:K09388 - ko00000 -
DMHIIBIA_03538 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
DMHIIBIA_03539 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
DMHIIBIA_03540 7.1e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
DMHIIBIA_03541 9.26e-69 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
DMHIIBIA_03542 4.41e-119 - - - S - - - membrane
DMHIIBIA_03543 2.66e-50 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_03544 1.14e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
DMHIIBIA_03545 2.25e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
DMHIIBIA_03546 3.98e-212 - - - S - - - Conserved hypothetical protein 698
DMHIIBIA_03547 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
DMHIIBIA_03548 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
DMHIIBIA_03549 8.07e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
DMHIIBIA_03550 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
DMHIIBIA_03551 2.72e-263 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
DMHIIBIA_03552 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
DMHIIBIA_03553 1.56e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DMHIIBIA_03554 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
DMHIIBIA_03555 1.4e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
DMHIIBIA_03556 2.25e-283 ywfA - - EGP - - - -transporter
DMHIIBIA_03557 1.63e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
DMHIIBIA_03558 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DMHIIBIA_03559 0.0 rocB - - E - - - arginine degradation protein
DMHIIBIA_03560 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
DMHIIBIA_03561 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DMHIIBIA_03562 6.37e-77 - - - - - - - -
DMHIIBIA_03563 9.44e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
DMHIIBIA_03564 3.89e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DMHIIBIA_03565 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DMHIIBIA_03566 6.62e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMHIIBIA_03567 1.22e-227 spsG - - M - - - Spore Coat
DMHIIBIA_03568 1.68e-170 spsF - - M ko:K07257 - ko00000 Spore Coat
DMHIIBIA_03569 1.43e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
DMHIIBIA_03570 1.02e-200 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
DMHIIBIA_03571 4.86e-280 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
DMHIIBIA_03572 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
DMHIIBIA_03573 5.24e-183 spsA - - M - - - Spore Coat
DMHIIBIA_03574 5.09e-85 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
DMHIIBIA_03575 2.17e-76 ywdK - - S - - - small membrane protein
DMHIIBIA_03576 2.19e-290 ywdJ - - F - - - Xanthine uracil
DMHIIBIA_03577 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
DMHIIBIA_03578 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DMHIIBIA_03579 4.49e-190 ywdF - - S - - - Glycosyltransferase like family 2
DMHIIBIA_03581 2.34e-114 ywdD - - - - - - -
DMHIIBIA_03582 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
DMHIIBIA_03583 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
DMHIIBIA_03584 5e-26 ywdA - - - - - - -
DMHIIBIA_03585 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
DMHIIBIA_03586 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_03587 3.85e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
DMHIIBIA_03589 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DMHIIBIA_03590 1.57e-234 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMHIIBIA_03591 4.47e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
DMHIIBIA_03592 3.18e-263 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
DMHIIBIA_03593 7.5e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
DMHIIBIA_03594 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
DMHIIBIA_03595 1.31e-81 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
DMHIIBIA_03596 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
DMHIIBIA_03597 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMHIIBIA_03598 3.67e-227 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
DMHIIBIA_03599 5.74e-48 ydaS - - S - - - membrane
DMHIIBIA_03600 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
DMHIIBIA_03601 4.03e-80 gtcA - - S - - - GtrA-like protein
DMHIIBIA_03602 1.52e-144 - - - K - - - Bacterial regulatory proteins, tetR family
DMHIIBIA_03604 1.77e-166 - - - H - - - Methionine biosynthesis protein MetW
DMHIIBIA_03605 3.31e-170 - - - S - - - Streptomycin biosynthesis protein StrF
DMHIIBIA_03606 1.21e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
DMHIIBIA_03607 1.54e-309 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
DMHIIBIA_03608 2.87e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DMHIIBIA_03609 5.29e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMHIIBIA_03610 4.83e-202 ywbI - - K - - - Transcriptional regulator
DMHIIBIA_03611 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
DMHIIBIA_03612 7.55e-143 ywbG - - M - - - effector of murein hydrolase
DMHIIBIA_03613 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
DMHIIBIA_03614 6.09e-176 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
DMHIIBIA_03615 1.03e-284 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
DMHIIBIA_03616 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
DMHIIBIA_03617 1.34e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMHIIBIA_03618 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DMHIIBIA_03619 1.42e-205 gspA - - M - - - General stress
DMHIIBIA_03620 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
DMHIIBIA_03621 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
DMHIIBIA_03622 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
DMHIIBIA_03623 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_03624 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
DMHIIBIA_03625 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DMHIIBIA_03626 5.98e-287 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DMHIIBIA_03627 9.09e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
DMHIIBIA_03628 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DMHIIBIA_03629 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_03630 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMHIIBIA_03631 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
DMHIIBIA_03632 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
DMHIIBIA_03633 5.36e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
DMHIIBIA_03634 2.33e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_03635 9.74e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMHIIBIA_03636 5.34e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
DMHIIBIA_03637 7.5e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
DMHIIBIA_03638 1.04e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DMHIIBIA_03639 9.69e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_03640 1.53e-63 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DMHIIBIA_03641 7e-303 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DMHIIBIA_03642 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DMHIIBIA_03643 8.18e-210 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
DMHIIBIA_03644 1.35e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DMHIIBIA_03645 1.53e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
DMHIIBIA_03646 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DMHIIBIA_03647 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
DMHIIBIA_03648 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
DMHIIBIA_03649 4.01e-197 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMHIIBIA_03650 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
DMHIIBIA_03651 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
DMHIIBIA_03652 3.07e-239 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
DMHIIBIA_03653 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
DMHIIBIA_03654 9.15e-287 cimH - - C - - - COG3493 Na citrate symporter
DMHIIBIA_03655 2.71e-197 yxkH - - G - - - Polysaccharide deacetylase
DMHIIBIA_03656 1.06e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DMHIIBIA_03657 2.25e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
DMHIIBIA_03658 3.28e-189 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DMHIIBIA_03659 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
DMHIIBIA_03660 2.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
DMHIIBIA_03661 5.46e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
DMHIIBIA_03664 1.75e-110 yxjI - - S - - - LURP-one-related
DMHIIBIA_03665 1.09e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
DMHIIBIA_03666 1.34e-199 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
DMHIIBIA_03667 5.75e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DMHIIBIA_03668 9.35e-120 - - - T - - - Domain of unknown function (DUF4163)
DMHIIBIA_03669 2.38e-65 yxiS - - - - - - -
DMHIIBIA_03670 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DMHIIBIA_03671 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
DMHIIBIA_03672 9.11e-182 bglS - - M - - - licheninase activity
DMHIIBIA_03674 5.2e-137 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
DMHIIBIA_03675 4.98e-280 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
DMHIIBIA_03676 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
DMHIIBIA_03679 4.09e-80 - - - S - - - SMI1-KNR4 cell-wall
DMHIIBIA_03680 1.63e-62 yxiI - - S - - - Protein of unknown function (DUF2716)
DMHIIBIA_03681 4.79e-27 - - - - - - - -
DMHIIBIA_03682 1.12e-11 yxiJ - - S - - - YxiJ-like protein
DMHIIBIA_03683 7.65e-139 - - - - - - - -
DMHIIBIA_03684 3.16e-98 - - - - - - - -
DMHIIBIA_03685 8.5e-91 yxiG - - - - - - -
DMHIIBIA_03686 1.02e-59 yxxG - - - - - - -
DMHIIBIA_03687 6.09e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
DMHIIBIA_03688 5.94e-208 yxxF - - EG - - - EamA-like transporter family
DMHIIBIA_03689 5.98e-95 yxiE - - T - - - Belongs to the universal stress protein A family
DMHIIBIA_03692 9.06e-91 - - - K - - - Transcriptional regulator
DMHIIBIA_03694 4.69e-39 - - - - - - - -
DMHIIBIA_03695 1.63e-129 - - - L - - - Replication protein
DMHIIBIA_03696 1.86e-18 - - - S - - - Domain of unknown function (DUF5082)
DMHIIBIA_03697 6.81e-59 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DMHIIBIA_03698 5.54e-232 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
DMHIIBIA_03699 2.51e-224 - - - L - - - AlwI restriction endonuclease
DMHIIBIA_03701 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
DMHIIBIA_03702 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
DMHIIBIA_03703 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
DMHIIBIA_03704 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DMHIIBIA_03705 1.44e-295 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
DMHIIBIA_03706 7.97e-224 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
DMHIIBIA_03707 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DMHIIBIA_03708 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
DMHIIBIA_03709 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DMHIIBIA_03710 8.25e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DMHIIBIA_03711 2.36e-219 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DMHIIBIA_03712 1.91e-192 yxeH - - S - - - hydrolases of the HAD superfamily
DMHIIBIA_03715 3.81e-33 yxeE - - - - - - -
DMHIIBIA_03716 5.09e-35 yxeD - - - - - - -
DMHIIBIA_03717 4.62e-45 - - - - - - - -
DMHIIBIA_03718 1.75e-229 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
DMHIIBIA_03719 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
DMHIIBIA_03720 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
DMHIIBIA_03721 1.89e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DMHIIBIA_03722 2.38e-225 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_03723 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03724 7.46e-200 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
DMHIIBIA_03725 1.7e-200 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
DMHIIBIA_03726 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
DMHIIBIA_03727 4.97e-248 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
DMHIIBIA_03728 5.22e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
DMHIIBIA_03729 3.12e-221 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
DMHIIBIA_03730 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
DMHIIBIA_03731 3.82e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
DMHIIBIA_03732 1.15e-198 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
DMHIIBIA_03733 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DMHIIBIA_03734 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DMHIIBIA_03735 6.81e-222 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
DMHIIBIA_03736 3.17e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DMHIIBIA_03737 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
DMHIIBIA_03739 1.69e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DMHIIBIA_03740 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DMHIIBIA_03741 4.8e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_03742 2.67e-250 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
DMHIIBIA_03743 1e-270 yxbF - - K - - - Bacterial regulatory proteins, tetR family
DMHIIBIA_03744 9.34e-317 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DMHIIBIA_03745 8.32e-190 yxaL - - S - - - PQQ-like domain
DMHIIBIA_03746 1.02e-84 - - - S - - - Family of unknown function (DUF5391)
DMHIIBIA_03747 9.97e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DMHIIBIA_03748 9.97e-252 - - - EGP - - - Major Facilitator Superfamily
DMHIIBIA_03749 3.71e-95 yxaI - - S - - - membrane protein domain
DMHIIBIA_03750 2.13e-159 - - - E - - - Ring-cleavage extradiol dioxygenase
DMHIIBIA_03751 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
DMHIIBIA_03752 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
DMHIIBIA_03753 3.55e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
DMHIIBIA_03754 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
DMHIIBIA_03755 4.54e-106 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
DMHIIBIA_03756 7.45e-195 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
DMHIIBIA_03757 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
DMHIIBIA_03758 1.15e-113 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
DMHIIBIA_03759 6.92e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DMHIIBIA_03760 2.59e-233 - - - S - - - Fusaric acid resistance protein-like
DMHIIBIA_03763 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMHIIBIA_03766 1.56e-275 yycP - - - - - - -
DMHIIBIA_03767 3.94e-170 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DMHIIBIA_03768 9.76e-230 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
DMHIIBIA_03769 1.19e-112 yycN - - K - - - Acetyltransferase
DMHIIBIA_03771 3.7e-259 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
DMHIIBIA_03772 2.64e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
DMHIIBIA_03773 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DMHIIBIA_03774 3.52e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
DMHIIBIA_03775 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
DMHIIBIA_03776 7.53e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
DMHIIBIA_03777 0.0 - - - S - - - ABC transporter
DMHIIBIA_03778 1.85e-252 - - - S - - - Major Facilitator Superfamily
DMHIIBIA_03779 0.0 - - - - - - - -
DMHIIBIA_03780 4.65e-241 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
DMHIIBIA_03781 2.06e-314 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
DMHIIBIA_03782 1.34e-13 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03783 1.1e-276 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMHIIBIA_03784 1.98e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
DMHIIBIA_03785 1.98e-194 yycI - - S - - - protein conserved in bacteria
DMHIIBIA_03786 0.0 yycH - - S - - - protein conserved in bacteria
DMHIIBIA_03787 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DMHIIBIA_03788 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DMHIIBIA_03793 1.55e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMHIIBIA_03794 3.05e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_03795 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
DMHIIBIA_03796 6.11e-36 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
DMHIIBIA_03798 5.12e-25 yycC - - K - - - YycC-like protein
DMHIIBIA_03799 2.61e-298 - - - M - - - Glycosyltransferase Family 4
DMHIIBIA_03800 6.38e-259 - - - S - - - Ecdysteroid kinase
DMHIIBIA_03801 1.27e-294 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
DMHIIBIA_03802 2.28e-306 - - - M - - - Glycosyltransferase Family 4
DMHIIBIA_03803 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
DMHIIBIA_03804 8.62e-133 - - - KLT - - - COG0515 Serine threonine protein kinase
DMHIIBIA_03805 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
DMHIIBIA_03806 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
DMHIIBIA_03807 2.9e-203 yybS - - S - - - membrane
DMHIIBIA_03809 2.25e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
DMHIIBIA_03810 2.64e-86 yybR - - K - - - Transcriptional regulator
DMHIIBIA_03811 1.2e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
DMHIIBIA_03812 1.96e-195 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DMHIIBIA_03813 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
DMHIIBIA_03814 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
DMHIIBIA_03815 5.42e-149 - - - K - - - FCD domain
DMHIIBIA_03816 2.74e-117 - - - S - - - PFAM DinB family protein
DMHIIBIA_03817 8.38e-202 - - - G - - - Major Facilitator Superfamily
DMHIIBIA_03818 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
DMHIIBIA_03819 1.7e-148 ydgI - - C - - - nitroreductase
DMHIIBIA_03820 6.79e-90 - - - K - - - Winged helix DNA-binding domain
DMHIIBIA_03821 4.43e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DMHIIBIA_03822 1.85e-99 yybA - - K - - - transcriptional
DMHIIBIA_03823 2.56e-55 yjcF - - S - - - Acetyltransferase (GNAT) domain
DMHIIBIA_03824 3.12e-08 yjcF - - S - - - Acetyltransferase (GNAT) domain
DMHIIBIA_03825 6.47e-209 - - - M - - - Domain of Unknown Function (DUF1259)
DMHIIBIA_03826 2.76e-86 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
DMHIIBIA_03827 1.63e-208 - - - K - - - Transcriptional regulator
DMHIIBIA_03828 1.93e-175 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
DMHIIBIA_03829 5.52e-315 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DMHIIBIA_03830 4.93e-167 - - - EG - - - EamA-like transporter family
DMHIIBIA_03831 1.44e-128 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMHIIBIA_03832 1.39e-100 - - - K - - - Transcriptional regulator
DMHIIBIA_03833 2.01e-18 - - - K - - - Transcriptional
DMHIIBIA_03834 2.32e-52 ebrA - - U ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DMHIIBIA_03835 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
DMHIIBIA_03836 1.64e-207 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
DMHIIBIA_03837 6.19e-315 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
DMHIIBIA_03838 3.43e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DMHIIBIA_03839 4.66e-230 ccpB - - K - - - Transcriptional regulator
DMHIIBIA_03840 3.69e-181 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
DMHIIBIA_03841 2.28e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMHIIBIA_03842 6.02e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
DMHIIBIA_03843 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMHIIBIA_03844 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DMHIIBIA_03845 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
DMHIIBIA_03846 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DMHIIBIA_03847 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DMHIIBIA_03848 1.82e-45 yyzM - - S - - - protein conserved in bacteria
DMHIIBIA_03849 1.67e-225 yyaD - - S - - - Membrane
DMHIIBIA_03850 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
DMHIIBIA_03851 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
DMHIIBIA_03852 2.38e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
DMHIIBIA_03853 3.82e-194 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
DMHIIBIA_03854 4.62e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
DMHIIBIA_03855 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DMHIIBIA_03856 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMHIIBIA_03857 4.45e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
DMHIIBIA_03858 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMHIIBIA_03859 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)