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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NHPIKHLF_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHPIKHLF_00002	9.85e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHPIKHLF_00003	9.62e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHPIKHLF_00004	9.78e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NHPIKHLF_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPIKHLF_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPIKHLF_00007	6.05e-89	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
NHPIKHLF_00008	4.7e-238	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NHPIKHLF_00009	2.81e-13	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NHPIKHLF_00010	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00011	8.41e-260	-	-	-	V	-	-	-	VanZ like family
NHPIKHLF_00013	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHPIKHLF_00014	3.12e-253	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHPIKHLF_00017	2.17e-160	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
NHPIKHLF_00019	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NHPIKHLF_00020	5.42e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NHPIKHLF_00021	4.48e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00022	9.48e-111	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00023	3.39e-148	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NHPIKHLF_00024	3.26e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
NHPIKHLF_00025	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
NHPIKHLF_00026	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00027	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NHPIKHLF_00028	2.43e-240	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00029	3.78e-271	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00030	2.65e-185	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_00031	8.25e-63	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_00032	7.96e-93	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_00033	3.16e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NHPIKHLF_00034	1.1e-198	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00035	2.79e-38	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00036	1.1e-91	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00037	1.28e-95	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00038	4.38e-147	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00040	5.07e-293	-	-	-	M	-	-	-	Protein of unknown function (DUF2961)
NHPIKHLF_00041	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00042	5.95e-240	-	-	-	K	ko:K05499	-	ko00000,ko03000	Periplasmic binding protein-like domain
NHPIKHLF_00043	0.0	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00044	5.42e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NHPIKHLF_00045	1.2e-298	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
NHPIKHLF_00046	1.31e-267	-	-	-	S	-	-	-	AAA ATPase domain
NHPIKHLF_00047	1.05e-154	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NHPIKHLF_00048	1.68e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NHPIKHLF_00049	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NHPIKHLF_00050	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
NHPIKHLF_00051	2.34e-210	-	-	-	-	-	-	-	-
NHPIKHLF_00052	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
NHPIKHLF_00053	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
NHPIKHLF_00054	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
NHPIKHLF_00055	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
NHPIKHLF_00056	1.93e-203	-	-	-	P	-	-	-	VTC domain
NHPIKHLF_00057	2.97e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
NHPIKHLF_00058	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
NHPIKHLF_00059	1.5e-160	-	-	-	S	ko:K07133	-	ko00000	AAA domain
NHPIKHLF_00060	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NHPIKHLF_00061	3.9e-08	-	-	-	S	ko:K07133	-	ko00000	AAA domain
NHPIKHLF_00062	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHPIKHLF_00063	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NHPIKHLF_00064	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPIKHLF_00065	3.07e-239	-	-	-	S	-	-	-	Protein conserved in bacteria
NHPIKHLF_00066	0.0	-	-	-	S	-	-	-	Amidohydrolase family
NHPIKHLF_00067	3.43e-260	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHPIKHLF_00068	2.08e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
NHPIKHLF_00069	1.54e-145	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPIKHLF_00070	3.21e-266	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00071	1.85e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_00072	1.22e-132	-	-	-	I	-	-	-	Sterol carrier protein
NHPIKHLF_00073	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHPIKHLF_00074	1.46e-47	-	-	-	-	-	-	-	-
NHPIKHLF_00075	8.43e-179	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
NHPIKHLF_00076	1.98e-100	crgA	-	-	D	-	-	-	Involved in cell division
NHPIKHLF_00077	6.78e-159	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NHPIKHLF_00078	3.94e-292	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHPIKHLF_00079	7.81e-155	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
NHPIKHLF_00080	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NHPIKHLF_00081	5.61e-224	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NHPIKHLF_00082	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NHPIKHLF_00083	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NHPIKHLF_00084	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
NHPIKHLF_00085	1.09e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NHPIKHLF_00086	8.7e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
NHPIKHLF_00087	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
NHPIKHLF_00088	1.86e-271	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
NHPIKHLF_00089	2.45e-119	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
NHPIKHLF_00090	8.01e-229	-	-	-	EG	-	-	-	EamA-like transporter family
NHPIKHLF_00091	6.41e-36	-	-	-	-	-	-	-	-
NHPIKHLF_00092	0.0	-	-	-	S	-	-	-	Putative esterase
NHPIKHLF_00093	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
NHPIKHLF_00094	4.46e-257	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHPIKHLF_00095	1.5e-170	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
NHPIKHLF_00096	4.63e-253	-	-	-	S	-	-	-	Fic/DOC family
NHPIKHLF_00097	8.97e-207	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_00098	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
NHPIKHLF_00099	5.5e-97	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NHPIKHLF_00100	1.01e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
NHPIKHLF_00101	5.82e-190	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NHPIKHLF_00103	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHPIKHLF_00104	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
NHPIKHLF_00105	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NHPIKHLF_00106	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NHPIKHLF_00107	3e-222	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NHPIKHLF_00109	7.06e-220	-	-	-	EG	-	-	-	EamA-like transporter family
NHPIKHLF_00110	2.2e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHPIKHLF_00111	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHPIKHLF_00112	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NHPIKHLF_00113	5.32e-205	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPIKHLF_00114	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPIKHLF_00115	3.57e-259	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_00117	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
NHPIKHLF_00118	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
NHPIKHLF_00119	7.98e-232	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_00120	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NHPIKHLF_00121	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHPIKHLF_00122	4.53e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
NHPIKHLF_00123	0.0	-	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00124	1.79e-267	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00125	2.17e-216	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00126	0.0	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHPIKHLF_00127	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHPIKHLF_00128	2.72e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00129	1.42e-246	-	-	-	K	-	-	-	Transcriptional regulator
NHPIKHLF_00130	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_00131	3.72e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00132	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
NHPIKHLF_00133	0.0	-	-	-	M	-	-	-	domain protein
NHPIKHLF_00134	4.58e-220	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHPIKHLF_00135	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NHPIKHLF_00136	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_00137	9.41e-297	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00138	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00139	1.57e-207	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00140	1.39e-188	traX	-	-	S	-	-	-	TraX protein
NHPIKHLF_00141	1.37e-248	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00142	5.26e-271	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
NHPIKHLF_00143	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NHPIKHLF_00144	6.81e-105	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHPIKHLF_00145	3.33e-222	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
NHPIKHLF_00146	5.76e-134	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
NHPIKHLF_00147	1.48e-128	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
NHPIKHLF_00148	7.9e-182	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
NHPIKHLF_00149	1.11e-163	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NHPIKHLF_00150	9.04e-172	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NHPIKHLF_00151	6.43e-160	-	-	-	D	-	-	-	bacterial-type flagellum organization
NHPIKHLF_00152	1.53e-244	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
NHPIKHLF_00153	2.08e-94	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
NHPIKHLF_00154	2.31e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
NHPIKHLF_00155	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
NHPIKHLF_00156	2.92e-75	-	-	-	U	-	-	-	TadE-like protein
NHPIKHLF_00157	3.01e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
NHPIKHLF_00158	2.3e-276	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
NHPIKHLF_00159	1.98e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_00160	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
NHPIKHLF_00161	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHPIKHLF_00162	1.17e-271	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHPIKHLF_00163	1.1e-90	-	-	-	V	-	-	-	Abi-like protein
NHPIKHLF_00164	1.31e-245	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
NHPIKHLF_00165	1.04e-172	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NHPIKHLF_00166	5.34e-124	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NHPIKHLF_00167	1.86e-269	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHPIKHLF_00168	1.64e-143	-	-	-	-	-	-	-	-
NHPIKHLF_00169	4.98e-220	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
NHPIKHLF_00170	1.68e-230	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_00171	1.2e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NHPIKHLF_00172	4.42e-205	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
NHPIKHLF_00173	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHPIKHLF_00174	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00175	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHPIKHLF_00176	2.91e-189	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00177	8.69e-230	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NHPIKHLF_00178	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPIKHLF_00180	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
NHPIKHLF_00181	1.68e-309	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NHPIKHLF_00182	3.99e-196	-	-	-	K	-	-	-	FCD
NHPIKHLF_00183	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NHPIKHLF_00184	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHPIKHLF_00185	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
NHPIKHLF_00186	2.87e-214	-	-	-	I	-	-	-	PAP2 superfamily
NHPIKHLF_00187	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPIKHLF_00188	2.38e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHPIKHLF_00189	1.85e-265	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NHPIKHLF_00190	3.67e-137	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_00191	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NHPIKHLF_00193	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHPIKHLF_00194	7.24e-136	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NHPIKHLF_00195	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NHPIKHLF_00196	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
NHPIKHLF_00197	9.13e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
NHPIKHLF_00198	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
NHPIKHLF_00199	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_00200	2.06e-157	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NHPIKHLF_00201	3.46e-189	-	-	-	-	-	-	-	-
NHPIKHLF_00202	1.72e-287	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NHPIKHLF_00203	1.38e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NHPIKHLF_00205	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHPIKHLF_00208	3.82e-134	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NHPIKHLF_00210	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
NHPIKHLF_00211	1.89e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
NHPIKHLF_00212	8.65e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
NHPIKHLF_00213	1.42e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NHPIKHLF_00214	1.63e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_00215	1.14e-186	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_00216	1.68e-102	-	-	-	S	-	-	-	FMN_bind
NHPIKHLF_00217	6.6e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00218	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NHPIKHLF_00219	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NHPIKHLF_00220	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NHPIKHLF_00221	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPIKHLF_00222	2.05e-192	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NHPIKHLF_00223	1.04e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
NHPIKHLF_00224	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHPIKHLF_00225	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NHPIKHLF_00227	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
NHPIKHLF_00228	2.29e-253	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
NHPIKHLF_00229	1.23e-194	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_00230	1.87e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHPIKHLF_00231	1.12e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
NHPIKHLF_00232	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
NHPIKHLF_00233	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
NHPIKHLF_00234	1.89e-308	dinF	-	-	V	-	-	-	MatE
NHPIKHLF_00235	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NHPIKHLF_00236	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
NHPIKHLF_00237	5.46e-182	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NHPIKHLF_00238	1.91e-52	-	-	-	S	-	-	-	granule-associated protein
NHPIKHLF_00239	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
NHPIKHLF_00240	3.98e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHPIKHLF_00241	8.13e-239	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPIKHLF_00242	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NHPIKHLF_00243	4.09e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NHPIKHLF_00244	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHPIKHLF_00245	1.72e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NHPIKHLF_00247	2.54e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NHPIKHLF_00248	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NHPIKHLF_00249	1.64e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
NHPIKHLF_00250	2.18e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
NHPIKHLF_00251	4.16e-143	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHPIKHLF_00252	7.31e-218	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
NHPIKHLF_00253	5.76e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_00254	7.3e-227	-	-	-	-	-	-	-	-
NHPIKHLF_00255	3.72e-205	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00256	6.22e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPIKHLF_00257	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHPIKHLF_00258	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPIKHLF_00259	2.37e-248	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_00260	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
NHPIKHLF_00261	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NHPIKHLF_00262	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHPIKHLF_00264	6.12e-47	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
NHPIKHLF_00265	3.97e-60	-	-	-	L	ko:K07485	-	ko00000	Transposase
NHPIKHLF_00267	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHPIKHLF_00268	2.65e-192	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00269	5.07e-159	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00270	7.65e-146	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00271	8.06e-156	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NHPIKHLF_00272	7.71e-82	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NHPIKHLF_00273	0.0	-	-	-	S	-	-	-	domain protein
NHPIKHLF_00274	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHPIKHLF_00275	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHPIKHLF_00276	4.01e-161	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHPIKHLF_00277	7.66e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
NHPIKHLF_00278	7.31e-154	-	-	-	-	-	-	-	-
NHPIKHLF_00279	9.55e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NHPIKHLF_00280	1.95e-119	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NHPIKHLF_00281	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NHPIKHLF_00282	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
NHPIKHLF_00284	8.61e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHPIKHLF_00285	1.76e-192	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NHPIKHLF_00286	1.65e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPIKHLF_00287	5.2e-103	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHPIKHLF_00288	4.49e-195	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPIKHLF_00289	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHPIKHLF_00290	1.2e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHPIKHLF_00291	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHPIKHLF_00292	2.1e-64	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHPIKHLF_00293	3.01e-166	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NHPIKHLF_00294	5.97e-215	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
NHPIKHLF_00295	2.35e-246	-	-	-	-	-	-	-	-
NHPIKHLF_00296	2.31e-232	-	-	-	-	-	-	-	-
NHPIKHLF_00297	5.13e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
NHPIKHLF_00298	3.19e-151	-	-	-	S	-	-	-	CYTH
NHPIKHLF_00301	3.27e-83	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
NHPIKHLF_00302	1.78e-241	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NHPIKHLF_00303	3.39e-229	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NHPIKHLF_00304	1.73e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NHPIKHLF_00305	8.7e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00306	4.85e-207	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00307	3.37e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00308	1.52e-301	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHPIKHLF_00309	3.41e-235	-	-	-	S	-	-	-	CAAX protease self-immunity
NHPIKHLF_00310	6.51e-176	-	-	-	M	-	-	-	Mechanosensitive ion channel
NHPIKHLF_00311	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
NHPIKHLF_00312	1.21e-15	-	-	-	L	-	-	-	Transposase DDE domain
NHPIKHLF_00313	5.5e-297	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_00314	7.57e-56	-	-	-	L	-	-	-	Transposase, Mutator family
NHPIKHLF_00315	2.01e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_00316	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00317	6.27e-121	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHPIKHLF_00318	5.21e-103	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHPIKHLF_00319	7.24e-97	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NHPIKHLF_00320	2.34e-130	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
NHPIKHLF_00322	6.77e-143	-	-	-	-	-	-	-	-
NHPIKHLF_00323	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
NHPIKHLF_00324	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
NHPIKHLF_00326	2.95e-64	-	-	-	-	-	-	-	-
NHPIKHLF_00327	5.54e-146	-	-	-	-	-	-	-	-
NHPIKHLF_00328	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHPIKHLF_00329	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHPIKHLF_00330	2.01e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_00331	2.37e-106	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_00332	2.57e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NHPIKHLF_00333	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NHPIKHLF_00334	8.48e-12	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NHPIKHLF_00335	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NHPIKHLF_00336	7.53e-33	-	-	-	-	-	-	-	-
NHPIKHLF_00337	2.46e-217	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
NHPIKHLF_00338	3.03e-257	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NHPIKHLF_00339	5.15e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHPIKHLF_00340	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NHPIKHLF_00341	9.48e-85	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NHPIKHLF_00342	1.53e-276	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NHPIKHLF_00343	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHPIKHLF_00344	5.27e-206	-	-	-	P	-	-	-	Cation efflux family
NHPIKHLF_00345	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHPIKHLF_00346	4.32e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
NHPIKHLF_00347	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
NHPIKHLF_00348	1.75e-92	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
NHPIKHLF_00349	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
NHPIKHLF_00350	8.22e-120	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NHPIKHLF_00351	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NHPIKHLF_00352	6.09e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHPIKHLF_00353	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NHPIKHLF_00354	8.53e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NHPIKHLF_00355	3.24e-159	-	-	-	-	-	-	-	-
NHPIKHLF_00356	9.97e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHPIKHLF_00357	2.31e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
NHPIKHLF_00358	9.67e-251	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NHPIKHLF_00359	7.41e-102	-	-	-	K	-	-	-	MerR, DNA binding
NHPIKHLF_00360	2.63e-150	-	-	-	-	-	-	-	-
NHPIKHLF_00361	1.89e-316	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHPIKHLF_00362	3.84e-186	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHPIKHLF_00363	6.52e-173	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHPIKHLF_00364	1.8e-224	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
NHPIKHLF_00367	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NHPIKHLF_00368	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00369	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00371	3.01e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHPIKHLF_00372	3.25e-223	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHPIKHLF_00373	9.13e-203	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPIKHLF_00374	8.26e-272	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_00376	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NHPIKHLF_00377	7.45e-46	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
NHPIKHLF_00378	4.48e-29	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
NHPIKHLF_00379	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
NHPIKHLF_00380	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00381	1.41e-220	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00382	7.07e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NHPIKHLF_00383	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00384	6.46e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_00385	0.0	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
NHPIKHLF_00386	2.09e-210	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NHPIKHLF_00387	1.02e-178	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NHPIKHLF_00388	1.93e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NHPIKHLF_00389	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NHPIKHLF_00390	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
NHPIKHLF_00391	1.47e-293	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NHPIKHLF_00392	6.21e-141	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NHPIKHLF_00393	7.51e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NHPIKHLF_00395	5.27e-130	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00396	1.84e-22	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00399	8.1e-21	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NHPIKHLF_00400	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NHPIKHLF_00401	6.29e-219	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
NHPIKHLF_00403	1.33e-11	wcaB	2.3.1.30	-	E	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
NHPIKHLF_00404	4.8e-212	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NHPIKHLF_00405	1.78e-195	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
NHPIKHLF_00406	9.06e-74	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NHPIKHLF_00407	2.54e-48	-	-	-	M	-	-	-	Glycosyltransferase Family 4
NHPIKHLF_00409	2.23e-261	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00410	7.68e-313	-	-	-	M	ko:K00713	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NHPIKHLF_00411	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NHPIKHLF_00412	3.97e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_00413	3.84e-171	-	-	-	H	-	-	-	Hexapeptide repeat of succinyl-transferase
NHPIKHLF_00414	1.42e-271	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NHPIKHLF_00415	3.88e-239	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_00417	1.6e-248	-	-	-	S	-	-	-	EpsG family
NHPIKHLF_00418	3.91e-246	-	-	-	G	-	-	-	Acyltransferase family
NHPIKHLF_00419	5.08e-67	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NHPIKHLF_00420	2.62e-79	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
NHPIKHLF_00421	4.96e-98	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00422	2.36e-222	-	-	-	L	-	-	-	Transposase
NHPIKHLF_00423	3.43e-33	-	-	-	L	-	-	-	IstB-like ATP binding protein
NHPIKHLF_00424	7.77e-307	-	-	-	L	-	-	-	HTH-like domain
NHPIKHLF_00425	5.67e-14	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHPIKHLF_00426	1.18e-114	-	-	-	S	-	-	-	RloB-like protein
NHPIKHLF_00427	1.14e-234	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
NHPIKHLF_00428	2.27e-27	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NHPIKHLF_00429	7.91e-63	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NHPIKHLF_00430	8.96e-26	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
NHPIKHLF_00432	1.35e-54	-	-	-	L	ko:K07483	-	ko00000	Transposase
NHPIKHLF_00433	1.42e-160	tnp3521a2	-	-	L	-	-	-	Integrase core domain
NHPIKHLF_00434	4.2e-79	-	-	-	S	-	-	-	Abi-like protein
NHPIKHLF_00435	9.89e-53	tnp3521a2	-	-	L	-	-	-	Integrase core domain
NHPIKHLF_00437	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NHPIKHLF_00438	3.5e-92	-	-	-	-	-	-	-	-
NHPIKHLF_00439	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
NHPIKHLF_00440	7.77e-269	-	-	-	-	-	-	-	-
NHPIKHLF_00441	1.47e-220	-	-	-	S	ko:K21688	-	ko00000	G5
NHPIKHLF_00442	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
NHPIKHLF_00443	1.76e-154	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
NHPIKHLF_00444	2e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NHPIKHLF_00445	3.08e-284	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
NHPIKHLF_00446	1.26e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NHPIKHLF_00447	4.05e-284	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
NHPIKHLF_00448	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
NHPIKHLF_00449	1.47e-244	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHPIKHLF_00450	2.41e-279	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NHPIKHLF_00451	2.7e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
NHPIKHLF_00452	0.0	pon1	-	-	M	-	-	-	Transglycosylase
NHPIKHLF_00453	3.48e-305	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NHPIKHLF_00454	3.08e-289	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NHPIKHLF_00455	3.61e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NHPIKHLF_00456	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
NHPIKHLF_00457	3.56e-298	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
NHPIKHLF_00458	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NHPIKHLF_00459	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NHPIKHLF_00460	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHPIKHLF_00461	1.03e-237	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
NHPIKHLF_00462	5.49e-131	-	-	-	-	-	-	-	-
NHPIKHLF_00463	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPIKHLF_00464	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPIKHLF_00465	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NHPIKHLF_00466	5.59e-309	-	-	-	S	-	-	-	Protein of unknown function DUF58
NHPIKHLF_00467	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
NHPIKHLF_00468	3.42e-281	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NHPIKHLF_00469	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NHPIKHLF_00470	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
NHPIKHLF_00471	9.52e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHPIKHLF_00472	2.77e-171	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHPIKHLF_00473	3.41e-207	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHPIKHLF_00474	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPIKHLF_00475	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
NHPIKHLF_00476	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHPIKHLF_00477	5.28e-159	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPIKHLF_00478	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00479	2.52e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHPIKHLF_00480	7.91e-270	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
NHPIKHLF_00481	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
NHPIKHLF_00482	2.5e-210	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
NHPIKHLF_00483	3.26e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHPIKHLF_00484	9.89e-198	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
NHPIKHLF_00485	3.75e-216	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
NHPIKHLF_00486	2.18e-222	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00487	3.69e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00488	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHPIKHLF_00489	1.77e-180	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
NHPIKHLF_00490	9.16e-240	-	-	-	K	-	-	-	Periplasmic binding protein domain
NHPIKHLF_00491	1.79e-216	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00492	7.07e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NHPIKHLF_00493	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00494	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00495	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00496	4.49e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NHPIKHLF_00497	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHPIKHLF_00498	1.92e-215	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00499	4.42e-195	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00500	5.35e-175	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
NHPIKHLF_00501	1.18e-177	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00502	1.42e-245	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHPIKHLF_00503	7.19e-280	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NHPIKHLF_00504	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NHPIKHLF_00505	4.78e-120	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHPIKHLF_00506	7.45e-134	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHPIKHLF_00507	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NHPIKHLF_00508	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPIKHLF_00509	6.86e-309	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
NHPIKHLF_00510	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHPIKHLF_00511	1.63e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHPIKHLF_00512	1.2e-148	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHPIKHLF_00513	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
NHPIKHLF_00514	1.36e-267	-	-	-	P	-	-	-	Citrate transporter
NHPIKHLF_00515	9.8e-41	-	-	-	-	-	-	-	-
NHPIKHLF_00516	8.43e-51	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
NHPIKHLF_00517	1.3e-204	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NHPIKHLF_00520	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00521	3.12e-291	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_00522	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NHPIKHLF_00523	2.81e-18	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
NHPIKHLF_00524	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHPIKHLF_00525	1.48e-109	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
NHPIKHLF_00526	2.56e-181	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00527	3.69e-248	-	-	-	M	-	-	-	Conserved repeat domain
NHPIKHLF_00528	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NHPIKHLF_00529	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHPIKHLF_00530	3.98e-231	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
NHPIKHLF_00531	1.46e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHPIKHLF_00532	4.92e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHPIKHLF_00533	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NHPIKHLF_00534	8.53e-98	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_00535	4.47e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_00536	9.71e-89	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_00537	8.08e-59	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NHPIKHLF_00538	9.84e-85	-	-	-	-	-	-	-	-
NHPIKHLF_00539	6.9e-40	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
NHPIKHLF_00540	1.14e-179	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
NHPIKHLF_00541	1.14e-255	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
NHPIKHLF_00542	3.79e-05	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
NHPIKHLF_00543	1.7e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NHPIKHLF_00544	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NHPIKHLF_00545	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
NHPIKHLF_00546	2.99e-309	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NHPIKHLF_00547	6.44e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NHPIKHLF_00548	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHPIKHLF_00549	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
NHPIKHLF_00550	1.4e-44	-	-	-	-	-	-	-	-
NHPIKHLF_00551	2.77e-17	-	-	-	C	-	-	-	Aldo/keto reductase family
NHPIKHLF_00552	2.67e-132	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
NHPIKHLF_00556	8.33e-187	-	-	-	-	-	-	-	-
NHPIKHLF_00557	4.43e-143	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
NHPIKHLF_00558	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
NHPIKHLF_00559	2.51e-297	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NHPIKHLF_00560	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NHPIKHLF_00561	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NHPIKHLF_00562	2.13e-294	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHPIKHLF_00563	1.05e-290	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NHPIKHLF_00564	3.69e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NHPIKHLF_00565	8.62e-252	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NHPIKHLF_00567	3.25e-142	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
NHPIKHLF_00568	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHPIKHLF_00569	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHPIKHLF_00570	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHPIKHLF_00571	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHPIKHLF_00572	1.8e-165	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
NHPIKHLF_00573	6.07e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NHPIKHLF_00574	1.24e-237	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NHPIKHLF_00575	2.74e-28	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHPIKHLF_00576	2.83e-39	-	-	-	S	ko:K07015	-	ko00000	polysaccharide biosynthetic process
NHPIKHLF_00577	1.43e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPIKHLF_00578	2.37e-111	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPIKHLF_00579	6.38e-87	-	-	-	K	-	-	-	MerR family regulatory protein
NHPIKHLF_00580	5.38e-249	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NHPIKHLF_00581	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NHPIKHLF_00582	4.18e-141	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
NHPIKHLF_00583	2.56e-216	-	-	-	C	-	-	-	Domain of unknown function
NHPIKHLF_00584	8.55e-305	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_00585	2.19e-181	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00586	1.92e-218	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00587	4.8e-203	-	-	-	P	-	-	-	Phosphate transporter family
NHPIKHLF_00588	1.12e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_00589	1.28e-181	-	-	-	K	-	-	-	LysR substrate binding domain
NHPIKHLF_00590	5.6e-130	-	-	-	K	-	-	-	LysR substrate binding domain
NHPIKHLF_00591	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHPIKHLF_00592	7.68e-309	-	-	-	V	-	-	-	MatE
NHPIKHLF_00593	1.27e-158	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
NHPIKHLF_00594	1e-148	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NHPIKHLF_00595	1.18e-53	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NHPIKHLF_00596	1.02e-237	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NHPIKHLF_00597	4.23e-63	-	4.1.1.44	-	L	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
NHPIKHLF_00599	0.0	-	-	-	M	-	-	-	probably involved in cell wall
NHPIKHLF_00600	0.0	-	3.2.1.14	GH18	S	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Carbohydrate binding domain
NHPIKHLF_00601	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NHPIKHLF_00602	2.46e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NHPIKHLF_00603	3.01e-163	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00604	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHPIKHLF_00605	5.05e-121	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHPIKHLF_00606	2.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NHPIKHLF_00607	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NHPIKHLF_00608	2.65e-217	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NHPIKHLF_00609	9.2e-136	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NHPIKHLF_00610	1.45e-174	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
NHPIKHLF_00611	1.93e-06	-	-	-	-	-	-	-	-
NHPIKHLF_00612	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NHPIKHLF_00613	1.31e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NHPIKHLF_00614	7.76e-299	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NHPIKHLF_00615	3.8e-56	-	-	-	O	-	-	-	Glutaredoxin
NHPIKHLF_00616	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NHPIKHLF_00617	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
NHPIKHLF_00618	9.81e-72	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NHPIKHLF_00619	5.74e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
NHPIKHLF_00620	4.68e-190	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NHPIKHLF_00621	1.08e-217	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NHPIKHLF_00622	3.96e-165	-	-	-	S	-	-	-	Vitamin K epoxide reductase
NHPIKHLF_00623	2.1e-214	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
NHPIKHLF_00624	2.77e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
NHPIKHLF_00625	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NHPIKHLF_00626	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHPIKHLF_00627	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NHPIKHLF_00628	2.12e-210	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NHPIKHLF_00629	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
NHPIKHLF_00631	1.65e-299	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
NHPIKHLF_00632	8.77e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NHPIKHLF_00633	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NHPIKHLF_00634	0.0	-	-	-	I	-	-	-	acetylesterase activity
NHPIKHLF_00635	6.84e-166	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NHPIKHLF_00636	1.3e-196	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHPIKHLF_00637	5.79e-172	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00638	2.17e-243	-	-	-	P	-	-	-	NMT1/THI5 like
NHPIKHLF_00639	7.02e-287	-	-	-	E	-	-	-	Aminotransferase class I and II
NHPIKHLF_00640	5.62e-182	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00641	2.25e-08	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
NHPIKHLF_00642	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPIKHLF_00643	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHPIKHLF_00644	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHPIKHLF_00645	3.32e-263	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NHPIKHLF_00646	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHPIKHLF_00647	4.82e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
NHPIKHLF_00648	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHPIKHLF_00649	4.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
NHPIKHLF_00650	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
NHPIKHLF_00651	4.38e-140	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NHPIKHLF_00652	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00653	1.62e-205	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NHPIKHLF_00654	1.99e-205	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPIKHLF_00655	4.35e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHPIKHLF_00656	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
NHPIKHLF_00657	7.8e-132	-	-	-	-	-	-	-	-
NHPIKHLF_00658	7.77e-258	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHPIKHLF_00659	7.94e-271	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHPIKHLF_00660	1.38e-225	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NHPIKHLF_00661	9.64e-317	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NHPIKHLF_00662	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHPIKHLF_00663	1.24e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHPIKHLF_00664	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHPIKHLF_00665	2.82e-110	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_00666	5.68e-40	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_00667	1.72e-58	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
NHPIKHLF_00668	1.62e-44	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NHPIKHLF_00669	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NHPIKHLF_00670	5.91e-38	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
NHPIKHLF_00671	1.19e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NHPIKHLF_00672	9.78e-190	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
NHPIKHLF_00673	5.26e-84	-	-	-	P	-	-	-	Rhodanese Homology Domain
NHPIKHLF_00674	6.92e-133	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NHPIKHLF_00675	9.39e-181	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NHPIKHLF_00676	2.29e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NHPIKHLF_00677	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPIKHLF_00678	1.28e-291	-	-	-	L	-	-	-	Tetratricopeptide repeat
NHPIKHLF_00679	1.05e-253	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
NHPIKHLF_00681	7.1e-177	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NHPIKHLF_00682	1.27e-149	-	-	-	-	-	-	-	-
NHPIKHLF_00683	9.24e-90	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NHPIKHLF_00685	1.51e-233	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPIKHLF_00686	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NHPIKHLF_00687	1.57e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NHPIKHLF_00688	5.39e-17	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_00689	1.32e-23	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_00690	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NHPIKHLF_00691	6.07e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00692	9.6e-156	-	-	-	S	-	-	-	ABC-2 family transporter protein
NHPIKHLF_00693	4.04e-125	-	-	-	S	-	-	-	ABC-2 family transporter protein
NHPIKHLF_00694	3.06e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00695	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
NHPIKHLF_00696	1.34e-299	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHPIKHLF_00697	7.62e-126	-	-	-	-	-	-	-	-
NHPIKHLF_00698	1.1e-177	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHPIKHLF_00699	9.63e-177	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NHPIKHLF_00700	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
NHPIKHLF_00701	1.65e-121	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NHPIKHLF_00702	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHPIKHLF_00703	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHPIKHLF_00704	9.02e-228	-	-	-	C	-	-	-	Aldo/keto reductase family
NHPIKHLF_00705	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHPIKHLF_00706	4.64e-114	-	-	-	D	-	-	-	Septum formation initiator
NHPIKHLF_00707	1.13e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
NHPIKHLF_00708	1.83e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NHPIKHLF_00710	3.19e-119	-	-	-	-	-	-	-	-
NHPIKHLF_00711	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NHPIKHLF_00712	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
NHPIKHLF_00713	4.11e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHPIKHLF_00714	7.86e-198	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
NHPIKHLF_00715	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHPIKHLF_00716	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NHPIKHLF_00717	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NHPIKHLF_00718	1.6e-306	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NHPIKHLF_00719	8.38e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NHPIKHLF_00720	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
NHPIKHLF_00721	0.0	-	-	-	-	-	-	-	-
NHPIKHLF_00722	2.13e-101	-	-	-	S	-	-	-	Zincin-like metallopeptidase
NHPIKHLF_00723	2.92e-190	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
NHPIKHLF_00724	5.28e-158	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
NHPIKHLF_00725	1.43e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHPIKHLF_00726	2.03e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
NHPIKHLF_00727	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHPIKHLF_00728	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
NHPIKHLF_00729	5.08e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHPIKHLF_00730	3.16e-174	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NHPIKHLF_00731	1.29e-206	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00732	6.45e-265	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NHPIKHLF_00733	3.75e-210	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHPIKHLF_00734	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NHPIKHLF_00735	7.22e-147	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHPIKHLF_00736	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHPIKHLF_00737	1.05e-225	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
NHPIKHLF_00738	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
NHPIKHLF_00739	1.12e-142	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
NHPIKHLF_00741	1.77e-168	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
NHPIKHLF_00742	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHPIKHLF_00743	4.64e-227	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
NHPIKHLF_00744	4.87e-163	-	-	-	L	-	-	-	NUDIX domain
NHPIKHLF_00745	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NHPIKHLF_00746	2.81e-17	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NHPIKHLF_00747	1.23e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
NHPIKHLF_00748	1.78e-161	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NHPIKHLF_00749	9.01e-137	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
NHPIKHLF_00751	0.0	-	2.1.1.72	-	L	ko:K06223,ko:K07318	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA binding domain with preference for A/T rich regions
NHPIKHLF_00752	0.0	-	-	-	S	-	-	-	AlwI restriction endonuclease
NHPIKHLF_00753	7.96e-48	-	-	-	-	-	-	-	-
NHPIKHLF_00754	4.36e-182	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NHPIKHLF_00755	7.12e-39	-	-	-	-	-	-	-	-
NHPIKHLF_00756	1.01e-68	-	-	-	J	-	-	-	tRNA 5'-leader removal
NHPIKHLF_00757	3.64e-184	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NHPIKHLF_00759	3.26e-274	-	-	-	-	-	-	-	-
NHPIKHLF_00760	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHPIKHLF_00761	8.03e-296	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHPIKHLF_00762	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
NHPIKHLF_00764	1.95e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPIKHLF_00765	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
NHPIKHLF_00766	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NHPIKHLF_00767	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NHPIKHLF_00768	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHPIKHLF_00769	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHPIKHLF_00770	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NHPIKHLF_00773	1.23e-195	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHPIKHLF_00774	1.81e-225	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NHPIKHLF_00775	1.15e-279	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHPIKHLF_00776	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00777	6.61e-284	-	-	-	S	-	-	-	Peptidase dimerisation domain
NHPIKHLF_00778	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHPIKHLF_00779	4.47e-54	-	-	-	-	-	-	-	-
NHPIKHLF_00780	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NHPIKHLF_00781	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHPIKHLF_00782	1.35e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
NHPIKHLF_00783	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NHPIKHLF_00784	3.47e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHPIKHLF_00785	3.21e-315	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NHPIKHLF_00786	6.43e-79	-	-	-	-	-	-	-	-
NHPIKHLF_00787	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHPIKHLF_00788	1.56e-156	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHPIKHLF_00789	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHPIKHLF_00792	5.51e-308	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NHPIKHLF_00793	6.11e-311	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NHPIKHLF_00794	2.76e-216	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NHPIKHLF_00795	3.95e-147	safC	-	-	S	-	-	-	O-methyltransferase
NHPIKHLF_00796	3.43e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NHPIKHLF_00797	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
NHPIKHLF_00798	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NHPIKHLF_00799	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NHPIKHLF_00800	4.34e-99	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
NHPIKHLF_00801	3.1e-29	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00802	2.26e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NHPIKHLF_00803	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
NHPIKHLF_00804	2.55e-216	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_00805	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NHPIKHLF_00806	6.52e-177	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_00807	0.0	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00808	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
NHPIKHLF_00809	2.3e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPIKHLF_00810	3.42e-199	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NHPIKHLF_00811	6.4e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
NHPIKHLF_00812	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00813	4.1e-144	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_00814	9.63e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHPIKHLF_00815	2.9e-171	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
NHPIKHLF_00816	4.8e-39	-	-	-	S	ko:K02890,ko:K07343	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
NHPIKHLF_00818	4.68e-314	-	-	-	V	-	-	-	MatE
NHPIKHLF_00819	0.0	-	-	-	L	-	-	-	ABC transporter
NHPIKHLF_00820	2.99e-32	-	-	-	L	-	-	-	Transposase, Mutator family
NHPIKHLF_00821	2.72e-300	-	-	-	K	-	-	-	Fic/DOC family
NHPIKHLF_00822	1.11e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
NHPIKHLF_00823	6.44e-205	-	-	-	J	-	-	-	Methyltransferase domain
NHPIKHLF_00824	9.63e-110	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
NHPIKHLF_00825	1.15e-68	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHPIKHLF_00826	5.09e-51	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NHPIKHLF_00827	2.28e-311	-	-	-	S	-	-	-	HipA-like C-terminal domain
NHPIKHLF_00828	2.42e-24	higA	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix
NHPIKHLF_00829	5.64e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
NHPIKHLF_00830	1.72e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_00831	7.74e-17	-	-	-	-	-	-	-	-
NHPIKHLF_00832	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NHPIKHLF_00833	1.45e-17	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NHPIKHLF_00834	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHPIKHLF_00835	6.23e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NHPIKHLF_00836	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPIKHLF_00837	2.02e-221	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_00838	2.15e-281	-	-	-	GK	-	-	-	ROK family
NHPIKHLF_00839	4.91e-204	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NHPIKHLF_00840	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
NHPIKHLF_00841	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
NHPIKHLF_00842	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
NHPIKHLF_00843	1.13e-150	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NHPIKHLF_00844	6.66e-79	-	-	-	L	-	-	-	Helix-turn-helix domain
NHPIKHLF_00845	2.52e-117	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NHPIKHLF_00846	2.2e-79	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPIKHLF_00847	2.21e-296	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NHPIKHLF_00848	7.93e-140	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NHPIKHLF_00849	7.29e-209	-	-	-	G	-	-	-	Phosphoglycerate mutase family
NHPIKHLF_00850	8.43e-299	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
NHPIKHLF_00851	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
NHPIKHLF_00852	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NHPIKHLF_00853	2.33e-240	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
NHPIKHLF_00854	2.24e-146	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
NHPIKHLF_00855	4.25e-140	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_00856	1.61e-292	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00857	8.96e-13	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NHPIKHLF_00858	7.53e-239	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00859	9.97e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHPIKHLF_00860	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHPIKHLF_00861	2.76e-92	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NHPIKHLF_00862	1.93e-30	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NHPIKHLF_00863	5.23e-130	-	-	-	-	-	-	-	-
NHPIKHLF_00864	2.38e-259	-	-	-	-	-	-	-	-
NHPIKHLF_00865	3.43e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
NHPIKHLF_00866	2.15e-138	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
NHPIKHLF_00867	2.55e-217	-	-	-	M	-	-	-	pfam nlp p60
NHPIKHLF_00868	1.56e-196	-	-	-	I	-	-	-	Serine aminopeptidase, S33
NHPIKHLF_00869	3.15e-40	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NHPIKHLF_00870	1.02e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NHPIKHLF_00871	2.47e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
NHPIKHLF_00872	3.1e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHPIKHLF_00873	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHPIKHLF_00874	3.12e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
NHPIKHLF_00875	3.14e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_00876	3.43e-207	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_00877	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHPIKHLF_00878	8.48e-200	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
NHPIKHLF_00879	5.2e-118	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
NHPIKHLF_00880	7.72e-70	-	-	-	S	-	-	-	SdpI/YhfL protein family
NHPIKHLF_00881	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NHPIKHLF_00882	3.14e-87	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHPIKHLF_00883	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NHPIKHLF_00884	1.41e-165	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NHPIKHLF_00885	9.04e-77	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
NHPIKHLF_00886	6.59e-48	-	-	-	-	-	-	-	-
NHPIKHLF_00887	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHPIKHLF_00888	2.12e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHPIKHLF_00889	7.29e-253	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHPIKHLF_00890	7.1e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NHPIKHLF_00891	4.31e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHPIKHLF_00892	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHPIKHLF_00893	9.97e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NHPIKHLF_00894	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHPIKHLF_00895	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHPIKHLF_00896	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
NHPIKHLF_00897	1.24e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
NHPIKHLF_00898	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NHPIKHLF_00899	3.08e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHPIKHLF_00900	8.33e-133	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NHPIKHLF_00901	2.19e-142	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NHPIKHLF_00902	1.6e-309	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHPIKHLF_00903	7.89e-212	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
NHPIKHLF_00905	1.48e-183	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHPIKHLF_00906	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NHPIKHLF_00907	2.8e-277	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
NHPIKHLF_00908	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHPIKHLF_00909	0.0	corC	-	-	S	-	-	-	CBS domain
NHPIKHLF_00910	2.23e-235	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHPIKHLF_00911	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NHPIKHLF_00912	2.32e-261	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
NHPIKHLF_00913	3.55e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
NHPIKHLF_00914	5.19e-309	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NHPIKHLF_00915	3.57e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NHPIKHLF_00916	2.59e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHPIKHLF_00917	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
NHPIKHLF_00918	1.29e-166	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_00919	9.23e-53	-	-	-	S	-	-	-	Helix-turn-helix domain
NHPIKHLF_00920	1.33e-141	-	-	-	-	-	-	-	-
NHPIKHLF_00921	2.52e-93	-	-	-	K	-	-	-	Transcriptional regulator
NHPIKHLF_00922	2.35e-65	-	-	-	-	-	-	-	-
NHPIKHLF_00923	2.61e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
NHPIKHLF_00925	6.69e-208	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_00926	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHPIKHLF_00927	6.48e-286	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00928	1.19e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, luxR family
NHPIKHLF_00929	2.89e-112	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00930	1.18e-73	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NHPIKHLF_00931	2.23e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00932	2.12e-166	-	-	-	-	-	-	-	-
NHPIKHLF_00933	5.85e-133	-	-	-	-	-	-	-	-
NHPIKHLF_00934	2.76e-191	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
NHPIKHLF_00935	2.29e-81	-	-	-	-	-	-	-	-
NHPIKHLF_00936	2.11e-94	-	-	-	-	-	-	-	-
NHPIKHLF_00937	2.25e-206	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NHPIKHLF_00938	5.17e-176	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NHPIKHLF_00939	8.36e-138	-	-	-	-	-	-	-	-
NHPIKHLF_00941	4.97e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
NHPIKHLF_00943	1.04e-64	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
NHPIKHLF_00944	1.27e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NHPIKHLF_00945	3.03e-232	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NHPIKHLF_00946	2.59e-159	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_00947	8.35e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHPIKHLF_00948	4.9e-123	-	-	-	-	-	-	-	-
NHPIKHLF_00949	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_00950	1.34e-260	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00951	3.52e-19	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_00954	1.39e-155	-	-	-	-	-	-	-	-
NHPIKHLF_00955	4.31e-65	-	-	-	-	-	-	-	-
NHPIKHLF_00956	6.4e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_00957	8.82e-124	-	-	-	K	-	-	-	FR47-like protein
NHPIKHLF_00958	1.4e-104	-	-	-	S	-	-	-	ASCH
NHPIKHLF_00959	7.63e-112	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
NHPIKHLF_00960	2.96e-241	-	-	-	V	-	-	-	VanZ like family
NHPIKHLF_00961	2.59e-129	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_00962	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
NHPIKHLF_00963	2.71e-199	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHPIKHLF_00964	2.61e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
NHPIKHLF_00965	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHPIKHLF_00966	4.36e-208	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHPIKHLF_00967	4.91e-239	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHPIKHLF_00968	8.36e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
NHPIKHLF_00969	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
NHPIKHLF_00970	3.56e-199	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NHPIKHLF_00971	2.23e-136	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPIKHLF_00972	7.29e-220	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NHPIKHLF_00973	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
NHPIKHLF_00974	2.17e-179	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
NHPIKHLF_00975	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
NHPIKHLF_00976	3.85e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHPIKHLF_00977	4.37e-84	-	-	-	-	-	-	-	-
NHPIKHLF_00978	9.94e-50	-	-	-	-	-	-	-	-
NHPIKHLF_00979	1.51e-178	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NHPIKHLF_00980	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NHPIKHLF_00981	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
NHPIKHLF_00982	4.22e-70	-	-	-	-	-	-	-	-
NHPIKHLF_00983	0.0	-	-	-	K	-	-	-	WYL domain
NHPIKHLF_00984	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NHPIKHLF_00985	3.75e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHPIKHLF_00987	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NHPIKHLF_00988	1.57e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHPIKHLF_00989	1.34e-181	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NHPIKHLF_00990	1.02e-42	-	-	-	-	-	-	-	-
NHPIKHLF_00991	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NHPIKHLF_00992	2.4e-297	-	-	-	-	-	-	-	-
NHPIKHLF_00993	5.31e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHPIKHLF_00994	1.2e-281	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHPIKHLF_00995	5.54e-131	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHPIKHLF_00996	5.33e-73	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NHPIKHLF_00997	1.82e-255	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHPIKHLF_00998	5.04e-139	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHPIKHLF_00999	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NHPIKHLF_01000	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NHPIKHLF_01001	7.63e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
NHPIKHLF_01002	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPIKHLF_01008	2.17e-169	-	-	-	S	-	-	-	PAC2 family
NHPIKHLF_01009	2.14e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHPIKHLF_01010	6.2e-199	-	-	-	G	-	-	-	Fructosamine kinase
NHPIKHLF_01011	1.88e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHPIKHLF_01012	4.92e-245	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHPIKHLF_01013	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
NHPIKHLF_01014	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHPIKHLF_01015	6.44e-305	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NHPIKHLF_01016	3.25e-244	-	-	-	-	-	-	-	-
NHPIKHLF_01017	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
NHPIKHLF_01018	4.04e-205	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHPIKHLF_01019	6.55e-223	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NHPIKHLF_01020	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NHPIKHLF_01021	4.88e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPIKHLF_01022	1.02e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NHPIKHLF_01023	5.76e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NHPIKHLF_01024	1.14e-230	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NHPIKHLF_01025	5.32e-243	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
NHPIKHLF_01026	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHPIKHLF_01027	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHPIKHLF_01028	5.6e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01029	4.49e-19	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NHPIKHLF_01030	1.15e-170	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHPIKHLF_01031	3.69e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHPIKHLF_01032	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NHPIKHLF_01033	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHPIKHLF_01034	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NHPIKHLF_01035	8.94e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NHPIKHLF_01036	2.12e-275	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01037	1.08e-39	-	-	-	-	-	-	-	-
NHPIKHLF_01038	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHPIKHLF_01039	1.19e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHPIKHLF_01040	1.42e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NHPIKHLF_01041	1.05e-224	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
NHPIKHLF_01042	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHPIKHLF_01043	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NHPIKHLF_01044	8.93e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NHPIKHLF_01045	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NHPIKHLF_01046	3.45e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHPIKHLF_01047	9.57e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NHPIKHLF_01048	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHPIKHLF_01050	1.18e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
NHPIKHLF_01051	1.56e-257	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NHPIKHLF_01052	4.32e-172	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NHPIKHLF_01054	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHPIKHLF_01055	1.99e-187	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
NHPIKHLF_01056	1.85e-115	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
NHPIKHLF_01057	1.96e-226	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NHPIKHLF_01058	2.82e-31	-	-	-	L	-	-	-	Transposase, Mutator family
NHPIKHLF_01059	2.67e-185	-	-	-	-	-	-	-	-
NHPIKHLF_01060	2.55e-137	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
NHPIKHLF_01061	2.08e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHPIKHLF_01062	3.44e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01063	4.78e-312	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
NHPIKHLF_01064	1.7e-106	-	-	-	-	-	-	-	-
NHPIKHLF_01065	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
NHPIKHLF_01066	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHPIKHLF_01067	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NHPIKHLF_01068	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
NHPIKHLF_01069	1.04e-78	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_01070	1.59e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_01072	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NHPIKHLF_01073	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHPIKHLF_01074	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NHPIKHLF_01075	3.96e-178	-	-	-	S	-	-	-	UPF0126 domain
NHPIKHLF_01076	6.5e-191	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01077	3.44e-152	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NHPIKHLF_01078	1.33e-209	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01079	6.67e-43	-	-	-	L	-	-	-	Excisionase from transposon Tn916
NHPIKHLF_01080	4.58e-289	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01081	2.36e-61	-	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHPIKHLF_01082	3.09e-69	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	kinase activity
NHPIKHLF_01083	1.89e-94	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01084	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
NHPIKHLF_01085	5.66e-13	-	-	-	-	-	-	-	-
NHPIKHLF_01086	7.04e-82	-	-	-	K	-	-	-	Protein of unknown function, DUF488
NHPIKHLF_01087	8.67e-101	-	-	-	-	-	-	-	-
NHPIKHLF_01088	3.67e-231	-	-	-	-	-	-	-	-
NHPIKHLF_01089	1.8e-84	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
NHPIKHLF_01090	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHPIKHLF_01091	4.61e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHPIKHLF_01092	4.13e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHPIKHLF_01093	5.99e-119	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NHPIKHLF_01094	2.25e-285	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHPIKHLF_01095	4.76e-222	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NHPIKHLF_01096	7.06e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHPIKHLF_01097	3.81e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NHPIKHLF_01098	7.92e-187	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHPIKHLF_01099	2.69e-192	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NHPIKHLF_01100	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPIKHLF_01101	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
NHPIKHLF_01102	5.83e-120	-	-	-	-	-	-	-	-
NHPIKHLF_01103	8.81e-264	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
NHPIKHLF_01104	8.16e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
NHPIKHLF_01105	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
NHPIKHLF_01106	2.35e-47	-	-	-	M	-	-	-	Peptidase family M23
NHPIKHLF_01108	1.88e-43	-	-	-	L	-	-	-	Phage integrase family
NHPIKHLF_01109	4.48e-25	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
NHPIKHLF_01111	1.6e-176	-	-	-	S	-	-	-	Fic/DOC family
NHPIKHLF_01112	1.98e-116	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
NHPIKHLF_01113	1.89e-253	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHPIKHLF_01114	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHPIKHLF_01115	4.89e-183	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
NHPIKHLF_01116	3.84e-91	-	-	-	-	-	-	-	-
NHPIKHLF_01118	9.59e-305	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_01119	1.49e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_01121	1.32e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHPIKHLF_01122	6.98e-137	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
NHPIKHLF_01123	6.91e-202	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
NHPIKHLF_01124	6.13e-112	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NHPIKHLF_01125	5.05e-221	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NHPIKHLF_01126	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NHPIKHLF_01127	8.17e-84	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
NHPIKHLF_01128	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NHPIKHLF_01129	3.06e-205	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NHPIKHLF_01130	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NHPIKHLF_01131	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NHPIKHLF_01132	1.36e-292	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
NHPIKHLF_01133	1.17e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
NHPIKHLF_01134	4.97e-220	-	-	-	EG	-	-	-	EamA-like transporter family
NHPIKHLF_01135	6.15e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
NHPIKHLF_01136	3.03e-42	-	-	-	-	-	-	-	-
NHPIKHLF_01137	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
NHPIKHLF_01138	5.99e-308	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NHPIKHLF_01139	8.57e-234	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_01140	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 85
NHPIKHLF_01141	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain
NHPIKHLF_01142	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NHPIKHLF_01143	9.12e-200	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01144	7.14e-210	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01145	1.93e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01146	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
NHPIKHLF_01147	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
NHPIKHLF_01148	2.27e-19	intA	-	-	L	-	-	-	Phage integrase family
NHPIKHLF_01149	2.79e-53	-	-	-	-	-	-	-	-
NHPIKHLF_01150	6.7e-218	-	-	-	S	-	-	-	Fic/DOC family
NHPIKHLF_01151	0.0	-	-	-	S	-	-	-	HipA-like C-terminal domain
NHPIKHLF_01153	1.31e-98	-	-	-	-	-	-	-	-
NHPIKHLF_01154	4.67e-132	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHPIKHLF_01155	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHPIKHLF_01156	5.02e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NHPIKHLF_01157	2.02e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
NHPIKHLF_01158	1.51e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
NHPIKHLF_01159	2e-296	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NHPIKHLF_01160	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NHPIKHLF_01162	7.12e-209	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_01163	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
NHPIKHLF_01164	7.03e-220	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPIKHLF_01165	2.17e-285	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01166	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
NHPIKHLF_01167	1.24e-248	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHPIKHLF_01168	1.45e-147	-	-	-	-	-	-	-	-
NHPIKHLF_01169	3.94e-250	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NHPIKHLF_01170	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
NHPIKHLF_01171	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NHPIKHLF_01172	7.98e-152	-	-	-	-	-	-	-	-
NHPIKHLF_01173	3.22e-246	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHPIKHLF_01174	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHPIKHLF_01175	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHPIKHLF_01176	7.82e-134	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NHPIKHLF_01177	1.29e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHPIKHLF_01178	9.29e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
NHPIKHLF_01179	1.55e-99	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHPIKHLF_01180	7.34e-123	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NHPIKHLF_01181	1.04e-152	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPIKHLF_01182	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
NHPIKHLF_01183	9.15e-192	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NHPIKHLF_01184	7.74e-232	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHPIKHLF_01185	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHPIKHLF_01186	1.99e-192	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NHPIKHLF_01187	1.59e-211	-	-	-	EG	-	-	-	EamA-like transporter family
NHPIKHLF_01188	4.02e-175	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NHPIKHLF_01189	4.74e-61	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_01190	1.11e-153	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01191	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHPIKHLF_01192	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NHPIKHLF_01193	6.18e-126	-	-	-	-	-	-	-	-
NHPIKHLF_01194	2.27e-307	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPIKHLF_01195	2.99e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
NHPIKHLF_01196	1.98e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
NHPIKHLF_01197	1.13e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NHPIKHLF_01198	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHPIKHLF_01199	2.81e-233	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHPIKHLF_01200	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01201	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHPIKHLF_01202	4.21e-242	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NHPIKHLF_01203	1.06e-189	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01204	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NHPIKHLF_01205	2.36e-56	-	-	-	-	-	-	-	-
NHPIKHLF_01206	1.65e-243	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NHPIKHLF_01207	3.21e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NHPIKHLF_01208	2.95e-101	-	-	-	-	-	-	-	-
NHPIKHLF_01209	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NHPIKHLF_01210	1.46e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
NHPIKHLF_01211	2.48e-175	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01212	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_01213	2.58e-310	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
NHPIKHLF_01214	4.53e-300	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
NHPIKHLF_01215	1.52e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
NHPIKHLF_01216	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NHPIKHLF_01217	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHPIKHLF_01218	3.2e-204	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
NHPIKHLF_01219	1.81e-149	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHPIKHLF_01220	9.39e-195	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHPIKHLF_01221	2.4e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NHPIKHLF_01222	4.94e-202	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
NHPIKHLF_01223	1.61e-271	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NHPIKHLF_01224	2.6e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHPIKHLF_01225	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NHPIKHLF_01226	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHPIKHLF_01227	1.18e-19	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
NHPIKHLF_01228	3.28e-174	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
NHPIKHLF_01229	1.23e-252	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPIKHLF_01230	9.93e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHPIKHLF_01231	5.06e-234	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NHPIKHLF_01232	2.09e-245	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NHPIKHLF_01233	3.31e-240	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NHPIKHLF_01234	3.96e-69	-	-	-	-	-	-	-	-
NHPIKHLF_01235	9.49e-178	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NHPIKHLF_01236	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHPIKHLF_01237	2.26e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_01238	2.52e-101	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_01239	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NHPIKHLF_01240	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NHPIKHLF_01241	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NHPIKHLF_01242	1.58e-127	-	-	-	F	-	-	-	NUDIX domain
NHPIKHLF_01243	5.02e-314	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
NHPIKHLF_01244	9.44e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPIKHLF_01245	1.59e-266	-	-	-	GK	-	-	-	ROK family
NHPIKHLF_01246	2e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_01247	2.54e-285	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_01248	1.66e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NHPIKHLF_01249	4.18e-124	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01250	1.74e-112	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHPIKHLF_01252	8.3e-231	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
NHPIKHLF_01253	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NHPIKHLF_01254	1.02e-277	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHPIKHLF_01255	2.45e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
NHPIKHLF_01256	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHPIKHLF_01257	3.33e-265	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHPIKHLF_01258	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHPIKHLF_01259	2.6e-200	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHPIKHLF_01260	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
NHPIKHLF_01261	1.29e-90	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NHPIKHLF_01262	2.54e-244	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHPIKHLF_01263	2.33e-120	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NHPIKHLF_01264	0.0	-	-	-	L	-	-	-	DNA helicase
NHPIKHLF_01265	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NHPIKHLF_01266	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHPIKHLF_01267	7.41e-70	-	-	-	M	-	-	-	Lysin motif
NHPIKHLF_01268	3.03e-168	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHPIKHLF_01269	1.39e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPIKHLF_01270	1.61e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NHPIKHLF_01271	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHPIKHLF_01272	5.71e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NHPIKHLF_01273	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
NHPIKHLF_01274	1.25e-280	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NHPIKHLF_01275	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHPIKHLF_01276	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
NHPIKHLF_01277	7.13e-169	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NHPIKHLF_01278	2.07e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHPIKHLF_01279	2.17e-162	-	-	-	-	-	-	-	-
NHPIKHLF_01280	4.75e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NHPIKHLF_01281	1.57e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHPIKHLF_01282	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHPIKHLF_01283	1.7e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
NHPIKHLF_01284	9.11e-198	-	-	-	S	-	-	-	Aldo/keto reductase family
NHPIKHLF_01285	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NHPIKHLF_01286	8.54e-214	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
NHPIKHLF_01287	7.18e-194	-	-	-	S	-	-	-	Amidohydrolase
NHPIKHLF_01288	8.04e-186	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NHPIKHLF_01289	4.89e-211	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
NHPIKHLF_01291	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
NHPIKHLF_01292	1.47e-212	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
NHPIKHLF_01294	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NHPIKHLF_01295	2.13e-256	-	-	-	K	-	-	-	WYL domain
NHPIKHLF_01296	4.29e-227	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NHPIKHLF_01297	1.72e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHPIKHLF_01298	1.2e-89	-	-	-	V	-	-	-	DivIVA protein
NHPIKHLF_01299	3.44e-60	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NHPIKHLF_01300	2.98e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHPIKHLF_01301	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHPIKHLF_01302	0.0	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPIKHLF_01303	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
NHPIKHLF_01304	8.24e-159	-	-	-	-	-	-	-	-
NHPIKHLF_01305	4.13e-179	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NHPIKHLF_01306	6.27e-136	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NHPIKHLF_01307	2.4e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NHPIKHLF_01308	6.65e-126	-	-	-	-	-	-	-	-
NHPIKHLF_01309	8.54e-218	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHPIKHLF_01310	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NHPIKHLF_01311	2.76e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
NHPIKHLF_01312	6.39e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NHPIKHLF_01313	1.64e-81	-	-	-	S	-	-	-	Thiamine-binding protein
NHPIKHLF_01314	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
NHPIKHLF_01315	5.58e-295	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_01316	5.01e-159	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_01317	2.01e-244	-	-	-	-	-	-	-	-
NHPIKHLF_01318	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
NHPIKHLF_01319	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_01320	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
NHPIKHLF_01321	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NHPIKHLF_01322	6.61e-181	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_01323	8.77e-193	-	-	-	C	-	-	-	Putative TM nitroreductase
NHPIKHLF_01324	1.55e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NHPIKHLF_01325	4.71e-133	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHPIKHLF_01326	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01327	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
NHPIKHLF_01328	1.66e-70	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NHPIKHLF_01329	2.26e-67	-	-	-	-	-	-	-	-
NHPIKHLF_01330	5.73e-239	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NHPIKHLF_01331	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01332	2.13e-40	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHPIKHLF_01333	2.53e-14	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NHPIKHLF_01334	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
NHPIKHLF_01335	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
NHPIKHLF_01336	1.47e-254	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NHPIKHLF_01338	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
NHPIKHLF_01339	6.56e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
NHPIKHLF_01340	0.0	-	-	-	I	-	-	-	PAP2 superfamily
NHPIKHLF_01341	1.27e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01342	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01343	3.16e-189	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHPIKHLF_01344	9.45e-198	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
NHPIKHLF_01345	4.46e-132	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
NHPIKHLF_01346	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHPIKHLF_01347	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NHPIKHLF_01348	0.0	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
NHPIKHLF_01349	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NHPIKHLF_01350	2.35e-67	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
NHPIKHLF_01351	2.31e-177	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
NHPIKHLF_01352	2.13e-15	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHPIKHLF_01353	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
NHPIKHLF_01354	1.14e-230	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
NHPIKHLF_01355	5.3e-241	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
NHPIKHLF_01356	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NHPIKHLF_01357	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHPIKHLF_01358	1.23e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
NHPIKHLF_01359	4.62e-149	-	-	-	-	-	-	-	-
NHPIKHLF_01360	2.38e-56	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
NHPIKHLF_01361	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHPIKHLF_01362	3.14e-115	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NHPIKHLF_01363	8.09e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHPIKHLF_01364	9.23e-247	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NHPIKHLF_01365	1.14e-209	-	-	-	S	-	-	-	Protein of unknown function DUF58
NHPIKHLF_01366	2.68e-118	-	-	-	-	-	-	-	-
NHPIKHLF_01367	3.07e-241	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NHPIKHLF_01368	1.04e-213	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NHPIKHLF_01369	8.64e-76	-	-	-	-	-	-	-	-
NHPIKHLF_01370	0.0	-	-	-	S	-	-	-	PGAP1-like protein
NHPIKHLF_01371	8.67e-143	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NHPIKHLF_01372	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
NHPIKHLF_01373	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
NHPIKHLF_01374	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
NHPIKHLF_01375	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NHPIKHLF_01376	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NHPIKHLF_01377	3.95e-223	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NHPIKHLF_01378	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
NHPIKHLF_01379	1.57e-175	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
NHPIKHLF_01380	2.06e-229	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
NHPIKHLF_01381	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHPIKHLF_01382	1.9e-104	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHPIKHLF_01383	1.33e-95	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHPIKHLF_01384	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
NHPIKHLF_01385	1.63e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NHPIKHLF_01386	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
NHPIKHLF_01387	3.13e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
NHPIKHLF_01388	5.82e-154	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
NHPIKHLF_01389	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPIKHLF_01390	8.38e-169	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NHPIKHLF_01391	2.43e-240	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHPIKHLF_01392	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NHPIKHLF_01393	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHPIKHLF_01394	2.77e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHPIKHLF_01395	1.28e-300	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01396	1.01e-174	-	-	-	L	-	-	-	IstB-like ATP binding protein
NHPIKHLF_01397	1.44e-86	-	-	-	L	-	-	-	HTH-like domain
NHPIKHLF_01398	1.17e-71	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01401	1.65e-48	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHPIKHLF_01402	2.48e-252	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHPIKHLF_01403	3.43e-170	cas4	3.1.12.1	-	L	ko:K07464,ko:K15342	-	ko00000,ko01000,ko02048,ko03400	Domain of unknown function DUF83
NHPIKHLF_01404	5.28e-201	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
NHPIKHLF_01405	0.0	-	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
NHPIKHLF_01406	8.1e-176	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
NHPIKHLF_01407	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
NHPIKHLF_01408	1.53e-17	-	-	-	L	ko:K07485	-	ko00000	Transposase
NHPIKHLF_01409	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHPIKHLF_01410	9.93e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPIKHLF_01411	4.01e-201	-	-	-	C	ko:K03326	-	ko00000,ko02000	C4-dicarboxylate anaerobic carrier
NHPIKHLF_01412	1.99e-131	rihA	-	-	F	ko:K01250,ko:K12700	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NHPIKHLF_01413	1.58e-56	-	-	-	K	-	-	-	acetyltransferase
NHPIKHLF_01414	4.32e-160	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_01415	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NHPIKHLF_01416	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01417	5.02e-117	-	-	-	K	-	-	-	MarR family
NHPIKHLF_01418	2.91e-233	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NHPIKHLF_01419	2.24e-307	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NHPIKHLF_01420	1.26e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
NHPIKHLF_01421	5.86e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NHPIKHLF_01423	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
NHPIKHLF_01424	5.49e-183	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_01425	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
NHPIKHLF_01426	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
NHPIKHLF_01427	1.89e-173	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHPIKHLF_01428	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NHPIKHLF_01429	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPIKHLF_01430	1.7e-55	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPIKHLF_01431	3.25e-116	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
NHPIKHLF_01432	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NHPIKHLF_01433	8.52e-91	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHPIKHLF_01434	1.28e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NHPIKHLF_01436	2.41e-259	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
NHPIKHLF_01437	2.39e-228	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NHPIKHLF_01438	3.68e-298	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
NHPIKHLF_01439	3.69e-258	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHPIKHLF_01440	5.04e-114	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NHPIKHLF_01441	1.5e-129	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHPIKHLF_01442	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01443	2.51e-218	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NHPIKHLF_01444	2.22e-315	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NHPIKHLF_01445	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NHPIKHLF_01446	2.91e-199	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NHPIKHLF_01447	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
NHPIKHLF_01448	3.81e-151	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NHPIKHLF_01449	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHPIKHLF_01450	6.64e-125	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
NHPIKHLF_01451	0.0	-	-	-	L	-	-	-	PIF1-like helicase
NHPIKHLF_01452	1.29e-154	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NHPIKHLF_01453	2.82e-175	-	-	-	K	ko:K05499	-	ko00000,ko03000	Periplasmic binding protein-like domain
NHPIKHLF_01454	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
NHPIKHLF_01455	4.02e-230	-	-	-	G	-	-	-	Transporter major facilitator family protein
NHPIKHLF_01456	3e-252	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
NHPIKHLF_01457	5.65e-235	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NHPIKHLF_01458	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHPIKHLF_01459	1.18e-275	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
NHPIKHLF_01460	2.92e-153	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NHPIKHLF_01461	8.3e-160	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01462	2.73e-205	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
NHPIKHLF_01463	1.78e-240	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHPIKHLF_01464	1.26e-195	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHPIKHLF_01465	8.9e-270	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
NHPIKHLF_01466	1.03e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHPIKHLF_01467	2.86e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHPIKHLF_01468	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NHPIKHLF_01470	2.36e-93	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
NHPIKHLF_01471	2.8e-186	-	-	-	-	-	-	-	-
NHPIKHLF_01472	7.76e-89	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHPIKHLF_01473	1.65e-208	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
NHPIKHLF_01474	7.22e-24	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
NHPIKHLF_01475	6.91e-118	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NHPIKHLF_01476	6.55e-223	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHPIKHLF_01478	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01479	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
NHPIKHLF_01480	8.55e-216	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
NHPIKHLF_01481	3.27e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
NHPIKHLF_01482	1.37e-288	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHPIKHLF_01483	1.65e-206	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHPIKHLF_01484	1.9e-153	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NHPIKHLF_01485	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHPIKHLF_01486	6.27e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NHPIKHLF_01487	8.23e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHPIKHLF_01488	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
NHPIKHLF_01489	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NHPIKHLF_01490	2.35e-245	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01491	7.16e-298	-	-	-	M	-	-	-	Glycosyl transferase family 21
NHPIKHLF_01492	0.0	-	-	-	S	-	-	-	AI-2E family transporter
NHPIKHLF_01493	1.09e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_01494	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NHPIKHLF_01495	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
NHPIKHLF_01498	4.73e-213	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHPIKHLF_01501	1.19e-15	-	-	-	S	-	-	-	Helix-turn-helix domain
NHPIKHLF_01502	2.47e-263	-	-	-	S	-	-	-	Helix-turn-helix domain
NHPIKHLF_01503	1.11e-106	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
NHPIKHLF_01504	1.14e-92	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
NHPIKHLF_01505	2.05e-51	-	-	-	-	-	-	-	-
NHPIKHLF_01506	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
NHPIKHLF_01507	7.27e-121	-	-	-	K	-	-	-	FR47-like protein
NHPIKHLF_01508	2.32e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
NHPIKHLF_01509	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
NHPIKHLF_01510	2.32e-58	-	-	-	S	-	-	-	Helix-turn-helix domain
NHPIKHLF_01511	3.59e-79	-	-	-	S	-	-	-	PIN domain
NHPIKHLF_01512	5.4e-41	-	-	-	-	-	-	-	-
NHPIKHLF_01513	4.99e-189	-	-	-	-	-	-	-	-
NHPIKHLF_01514	8.76e-55	-	-	-	S	-	-	-	PrgI family protein
NHPIKHLF_01515	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
NHPIKHLF_01516	4.39e-253	-	-	-	M	-	-	-	CHAP domain
NHPIKHLF_01517	8.84e-127	-	-	-	-	-	-	-	-
NHPIKHLF_01518	2.4e-57	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
NHPIKHLF_01520	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
NHPIKHLF_01522	1.58e-70	-	-	-	-	-	-	-	-
NHPIKHLF_01523	6.43e-286	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
NHPIKHLF_01524	2.84e-63	-	-	-	-	-	-	-	-
NHPIKHLF_01525	1.4e-55	-	-	-	-	-	-	-	-
NHPIKHLF_01526	2.95e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
NHPIKHLF_01527	1.72e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
NHPIKHLF_01528	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
NHPIKHLF_01529	4.39e-88	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NHPIKHLF_01530	2.1e-78	-	-	-	-	-	-	-	-
NHPIKHLF_01531	1.57e-62	-	-	-	-	-	-	-	-
NHPIKHLF_01532	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
NHPIKHLF_01533	9.42e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
NHPIKHLF_01534	3.29e-101	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NHPIKHLF_01535	1.33e-229	intA	-	-	L	-	-	-	Phage integrase family
NHPIKHLF_01537	4.42e-19	-	-	-	L	-	-	-	Phage integrase family
NHPIKHLF_01538	1.82e-15	-	-	-	M	-	-	-	Cell surface antigen C-terminus
NHPIKHLF_01539	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NHPIKHLF_01540	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
NHPIKHLF_01541	1.98e-234	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NHPIKHLF_01542	1.65e-27	-	-	-	L	-	-	-	Helix-turn-helix domain
NHPIKHLF_01543	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01544	1.4e-280	-	-	-	GK	-	-	-	ROK family
NHPIKHLF_01545	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NHPIKHLF_01546	4.47e-08	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NHPIKHLF_01547	2.94e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NHPIKHLF_01548	1.12e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHPIKHLF_01549	1.39e-142	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01550	2.43e-15	-	-	-	E	-	-	-	AzlC protein
NHPIKHLF_01551	3.01e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
NHPIKHLF_01552	8.78e-164	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
NHPIKHLF_01553	1.73e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPIKHLF_01554	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
NHPIKHLF_01555	1.36e-241	-	-	-	T	-	-	-	Universal stress protein family
NHPIKHLF_01556	8.46e-70	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NHPIKHLF_01557	8.97e-48	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
NHPIKHLF_01558	1.3e-141	-	-	-	M	-	-	-	NlpC/P60 family
NHPIKHLF_01559	2.54e-217	-	-	-	S	-	-	-	CHAP domain
NHPIKHLF_01560	1.49e-273	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHPIKHLF_01561	6.59e-44	-	-	-	-	-	-	-	-
NHPIKHLF_01562	1.3e-238	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHPIKHLF_01563	6.31e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NHPIKHLF_01564	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHPIKHLF_01565	3.23e-221	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NHPIKHLF_01566	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NHPIKHLF_01568	1.02e-280	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
NHPIKHLF_01569	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
NHPIKHLF_01570	4.35e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
NHPIKHLF_01571	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NHPIKHLF_01572	7.38e-108	-	-	-	-	-	-	-	-
NHPIKHLF_01573	0.0	pspC	-	-	KT	-	-	-	PspC domain
NHPIKHLF_01574	1.64e-300	tcsS3	-	-	KT	-	-	-	PspC domain
NHPIKHLF_01575	1.01e-152	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NHPIKHLF_01576	4.59e-226	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHPIKHLF_01577	6.93e-261	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
NHPIKHLF_01578	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
NHPIKHLF_01579	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
NHPIKHLF_01580	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01581	2.85e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01583	1.47e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHPIKHLF_01584	3.39e-257	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NHPIKHLF_01585	6.85e-107	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NHPIKHLF_01586	2.6e-66	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
NHPIKHLF_01587	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
NHPIKHLF_01588	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NHPIKHLF_01589	4.45e-252	-	-	-	S	-	-	-	Protein conserved in bacteria
NHPIKHLF_01590	5.2e-98	-	-	-	K	-	-	-	Transcriptional regulator
NHPIKHLF_01591	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHPIKHLF_01592	3.7e-240	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPIKHLF_01593	4.47e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHPIKHLF_01594	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NHPIKHLF_01595	2.38e-132	-	-	-	-	-	-	-	-
NHPIKHLF_01596	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHPIKHLF_01597	1.01e-278	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
NHPIKHLF_01598	5.24e-278	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHPIKHLF_01599	8.26e-106	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHPIKHLF_01600	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHPIKHLF_01601	1.3e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NHPIKHLF_01602	4.1e-164	-	-	-	-	-	-	-	-
NHPIKHLF_01603	6.91e-124	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_01605	1.07e-196	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
NHPIKHLF_01606	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
NHPIKHLF_01607	1.04e-217	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHPIKHLF_01608	5.53e-89	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NHPIKHLF_01609	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPIKHLF_01610	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHPIKHLF_01611	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHPIKHLF_01612	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NHPIKHLF_01613	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHPIKHLF_01614	2.57e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHPIKHLF_01615	4.67e-316	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHPIKHLF_01616	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHPIKHLF_01617	3.26e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
NHPIKHLF_01618	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHPIKHLF_01619	3.09e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHPIKHLF_01620	5.43e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHPIKHLF_01621	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHPIKHLF_01622	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPIKHLF_01623	1.95e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHPIKHLF_01624	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHPIKHLF_01625	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHPIKHLF_01626	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHPIKHLF_01627	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NHPIKHLF_01628	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHPIKHLF_01629	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHPIKHLF_01630	3.14e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHPIKHLF_01631	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHPIKHLF_01632	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHPIKHLF_01633	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHPIKHLF_01634	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NHPIKHLF_01635	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHPIKHLF_01636	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NHPIKHLF_01637	3.82e-176	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NHPIKHLF_01638	2.08e-184	-	-	-	S	-	-	-	YwiC-like protein
NHPIKHLF_01639	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NHPIKHLF_01640	2.64e-217	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHPIKHLF_01641	6.77e-247	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
NHPIKHLF_01642	1.73e-248	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01643	3.99e-274	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NHPIKHLF_01644	2.66e-97	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPIKHLF_01645	3.04e-296	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHPIKHLF_01646	2.47e-227	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NHPIKHLF_01647	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
NHPIKHLF_01648	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NHPIKHLF_01649	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHPIKHLF_01650	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NHPIKHLF_01651	9.47e-152	-	-	-	-	-	-	-	-
NHPIKHLF_01652	6.88e-144	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
NHPIKHLF_01653	6.04e-236	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPIKHLF_01654	1.04e-147	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
NHPIKHLF_01655	1.16e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHPIKHLF_01656	5.08e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01657	2.82e-207	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01658	3.13e-311	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01659	7.41e-277	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_01660	2.08e-30	-	-	-	-	-	-	-	-
NHPIKHLF_01662	1.17e-79	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
NHPIKHLF_01663	4.87e-30	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
NHPIKHLF_01664	3.49e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPIKHLF_01665	8.83e-286	dapC	-	-	E	-	-	-	Aminotransferase class I and II
NHPIKHLF_01666	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
NHPIKHLF_01667	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
NHPIKHLF_01668	1.17e-287	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NHPIKHLF_01669	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NHPIKHLF_01673	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHPIKHLF_01674	1.38e-185	-	-	-	-	-	-	-	-
NHPIKHLF_01675	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHPIKHLF_01676	2.47e-77	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NHPIKHLF_01677	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
NHPIKHLF_01678	9.74e-138	-	-	-	NO	-	-	-	SAF
NHPIKHLF_01679	6.79e-24	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NHPIKHLF_01680	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NHPIKHLF_01681	1.79e-282	-	-	-	T	-	-	-	Forkhead associated domain
NHPIKHLF_01682	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHPIKHLF_01683	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHPIKHLF_01684	1.39e-186	-	-	-	S	-	-	-	alpha beta
NHPIKHLF_01685	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NHPIKHLF_01686	1.57e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPIKHLF_01687	1.86e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NHPIKHLF_01688	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NHPIKHLF_01689	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
NHPIKHLF_01690	1.23e-181	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NHPIKHLF_01691	6.34e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NHPIKHLF_01692	7.16e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NHPIKHLF_01693	1.73e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHPIKHLF_01694	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHPIKHLF_01695	9.77e-279	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHPIKHLF_01696	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NHPIKHLF_01697	3.83e-122	-	-	-	D	-	-	-	nuclear chromosome segregation
NHPIKHLF_01698	5.05e-161	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHPIKHLF_01699	3.28e-194	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NHPIKHLF_01700	4.29e-254	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NHPIKHLF_01701	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
NHPIKHLF_01702	4.12e-226	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NHPIKHLF_01703	2.75e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
NHPIKHLF_01704	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
NHPIKHLF_01705	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NHPIKHLF_01706	2.28e-250	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NHPIKHLF_01707	4.38e-303	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NHPIKHLF_01708	7.96e-169	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHPIKHLF_01709	1.41e-79	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
NHPIKHLF_01710	7.21e-72	-	-	-	L	-	-	-	RelB antitoxin
NHPIKHLF_01711	1.18e-34	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
NHPIKHLF_01712	1.8e-247	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHPIKHLF_01713	5.94e-148	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NHPIKHLF_01717	2.18e-72	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
NHPIKHLF_01719	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
NHPIKHLF_01720	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NHPIKHLF_01721	4.1e-120	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NHPIKHLF_01722	1.76e-207	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NHPIKHLF_01723	0.0	-	-	-	-	-	-	-	-
NHPIKHLF_01724	3.74e-211	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NHPIKHLF_01725	1.75e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHPIKHLF_01726	8.3e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHPIKHLF_01727	9.79e-188	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_01728	1.43e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NHPIKHLF_01729	5.79e-43	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHPIKHLF_01731	4.6e-291	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NHPIKHLF_01732	8.78e-301	-	-	-	G	-	-	-	polysaccharide deacetylase
NHPIKHLF_01733	1.93e-252	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPIKHLF_01734	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHPIKHLF_01735	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NHPIKHLF_01736	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NHPIKHLF_01737	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
NHPIKHLF_01738	3.47e-293	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NHPIKHLF_01739	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NHPIKHLF_01740	6.01e-214	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
NHPIKHLF_01741	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
NHPIKHLF_01742	3.33e-271	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NHPIKHLF_01743	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NHPIKHLF_01744	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
NHPIKHLF_01745	5.55e-244	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NHPIKHLF_01746	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
NHPIKHLF_01747	1.44e-176	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01748	3.47e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
NHPIKHLF_01749	4.05e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHPIKHLF_01750	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
NHPIKHLF_01751	7.94e-232	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHPIKHLF_01752	2.16e-301	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NHPIKHLF_01753	1.84e-66	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NHPIKHLF_01754	8.89e-72	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NHPIKHLF_01755	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHPIKHLF_01756	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NHPIKHLF_01757	4.49e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHPIKHLF_01758	5.71e-282	-	-	-	G	-	-	-	Transmembrane secretion effector
NHPIKHLF_01759	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPIKHLF_01760	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NHPIKHLF_01761	2.62e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NHPIKHLF_01762	3.01e-155	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01763	2.11e-178	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01764	6.1e-135	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
NHPIKHLF_01765	9.29e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHPIKHLF_01766	4.34e-282	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NHPIKHLF_01767	6.91e-27	-	-	-	T	-	-	-	Histidine kinase
NHPIKHLF_01768	4.33e-17	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
NHPIKHLF_01769	6.62e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPIKHLF_01770	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPIKHLF_01771	2.37e-181	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
NHPIKHLF_01772	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NHPIKHLF_01773	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NHPIKHLF_01774	0.0	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
NHPIKHLF_01775	8.48e-177	-	-	-	-	-	-	-	-
NHPIKHLF_01776	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
NHPIKHLF_01777	4.92e-65	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01778	4.9e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHPIKHLF_01779	1.24e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHPIKHLF_01780	6.31e-275	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NHPIKHLF_01781	5.84e-278	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHPIKHLF_01783	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHPIKHLF_01784	5.7e-209	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
NHPIKHLF_01785	1.25e-203	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NHPIKHLF_01786	1.54e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
NHPIKHLF_01787	7.55e-220	-	-	-	-	-	-	-	-
NHPIKHLF_01788	3.28e-297	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NHPIKHLF_01789	7.78e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
NHPIKHLF_01790	2.66e-08	-	-	-	S	-	-	-	PIN domain
NHPIKHLF_01791	4.14e-91	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01792	4.29e-191	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01793	9.88e-57	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
NHPIKHLF_01794	1.41e-72	-	-	-	G	-	-	-	Branched-chain amino acid transport system / permease component
NHPIKHLF_01795	2.84e-95	-	-	-	P	-	-	-	branched-chain amino acid ABC transporter, permease protein
NHPIKHLF_01796	2.53e-144	-	-	-	G	-	-	-	ATPases associated with a variety of cellular activities
NHPIKHLF_01797	3.96e-100	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
NHPIKHLF_01798	7.81e-211	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NHPIKHLF_01799	1.29e-91	xylR	-	-	GK	-	-	-	ROK family
NHPIKHLF_01800	8.04e-155	-	-	-	-	-	-	-	-
NHPIKHLF_01801	1.21e-243	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_01802	1.18e-27	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NHPIKHLF_01803	4.44e-45	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NHPIKHLF_01804	8.84e-74	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
NHPIKHLF_01805	3.79e-76	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
NHPIKHLF_01806	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01808	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
NHPIKHLF_01809	9.08e-317	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NHPIKHLF_01810	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
NHPIKHLF_01811	1.16e-243	-	-	-	I	-	-	-	Acyltransferase family
NHPIKHLF_01812	2.11e-219	-	1.1.1.339	-	GM	ko:K19180	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NHPIKHLF_01813	2.57e-222	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01814	1.23e-88	-	-	-	L	-	-	-	PFAM Integrase catalytic
NHPIKHLF_01815	2.94e-188	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
NHPIKHLF_01816	1.74e-290	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01817	6.02e-184	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NHPIKHLF_01818	1.63e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHPIKHLF_01819	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHPIKHLF_01820	1.61e-220	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHPIKHLF_01821	5.3e-287	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NHPIKHLF_01822	2.67e-24	-	-	-	-	-	-	-	-
NHPIKHLF_01823	6.86e-246	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
NHPIKHLF_01824	0.0	-	-	-	V	-	-	-	ABC transporter permease
NHPIKHLF_01825	1.97e-245	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_01826	3.29e-185	-	-	-	T	ko:K06950	-	ko00000	HD domain
NHPIKHLF_01827	4.08e-204	-	-	-	S	-	-	-	Glutamine amidotransferase domain
NHPIKHLF_01828	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NHPIKHLF_01829	2e-239	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NHPIKHLF_01830	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NHPIKHLF_01831	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NHPIKHLF_01832	5.54e-29	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
NHPIKHLF_01833	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
NHPIKHLF_01834	1.01e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NHPIKHLF_01835	2.58e-196	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01836	7.71e-228	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01837	8.2e-308	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01838	5.57e-247	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NHPIKHLF_01839	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
NHPIKHLF_01840	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
NHPIKHLF_01841	1.48e-71	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NHPIKHLF_01842	2.41e-44	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NHPIKHLF_01843	4.52e-25	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
NHPIKHLF_01844	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHPIKHLF_01845	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHPIKHLF_01846	3.51e-226	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHPIKHLF_01847	8.66e-229	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01848	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NHPIKHLF_01849	7.04e-63	-	-	-	-	-	-	-	-
NHPIKHLF_01850	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHPIKHLF_01851	5.33e-156	-	-	-	-	-	-	-	-
NHPIKHLF_01852	3.52e-231	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHPIKHLF_01854	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
NHPIKHLF_01855	1.29e-232	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHPIKHLF_01856	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
NHPIKHLF_01857	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NHPIKHLF_01858	1.57e-118	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHPIKHLF_01859	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NHPIKHLF_01860	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHPIKHLF_01861	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHPIKHLF_01862	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
NHPIKHLF_01863	8.13e-137	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NHPIKHLF_01864	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NHPIKHLF_01865	3.3e-200	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01866	8.42e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHPIKHLF_01867	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01868	4.16e-175	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
NHPIKHLF_01869	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
NHPIKHLF_01870	6.08e-177	nfrA	-	-	C	-	-	-	Nitroreductase family
NHPIKHLF_01871	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NHPIKHLF_01872	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
NHPIKHLF_01873	6.32e-55	-	-	-	-	-	-	-	-
NHPIKHLF_01875	7.18e-183	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
NHPIKHLF_01876	3.3e-295	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHPIKHLF_01877	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NHPIKHLF_01878	3.04e-198	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01879	3.37e-202	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHPIKHLF_01880	1.62e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHPIKHLF_01881	9.36e-296	-	-	-	GK	-	-	-	ROK family
NHPIKHLF_01882	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NHPIKHLF_01883	1.08e-105	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHPIKHLF_01884	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
NHPIKHLF_01885	4.35e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NHPIKHLF_01886	1.2e-186	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
NHPIKHLF_01887	5.44e-197	-	-	-	-	-	-	-	-
NHPIKHLF_01888	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
NHPIKHLF_01889	1.04e-130	-	-	-	-	-	-	-	-
NHPIKHLF_01890	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NHPIKHLF_01891	1.55e-20	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHPIKHLF_01892	1.58e-112	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NHPIKHLF_01893	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NHPIKHLF_01894	2.78e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NHPIKHLF_01895	2.26e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPIKHLF_01896	6.27e-215	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NHPIKHLF_01897	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NHPIKHLF_01898	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
NHPIKHLF_01899	7.78e-200	-	-	-	-	-	-	-	-
NHPIKHLF_01900	3.02e-229	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHPIKHLF_01901	7.72e-282	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NHPIKHLF_01902	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
NHPIKHLF_01903	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHPIKHLF_01904	7.15e-176	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
NHPIKHLF_01905	3.12e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NHPIKHLF_01906	3.61e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHPIKHLF_01907	1.66e-95	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHPIKHLF_01908	3.69e-278	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHPIKHLF_01909	2.58e-182	-	-	-	K	-	-	-	LytTr DNA-binding domain
NHPIKHLF_01910	3.28e-313	-	-	-	T	-	-	-	GHKL domain
NHPIKHLF_01911	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPIKHLF_01913	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPIKHLF_01914	2.09e-115	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NHPIKHLF_01915	1.34e-56	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NHPIKHLF_01916	3.06e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHPIKHLF_01917	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
NHPIKHLF_01918	7.8e-156	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHPIKHLF_01919	8.72e-163	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
NHPIKHLF_01920	1.73e-96	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
NHPIKHLF_01921	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
NHPIKHLF_01922	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NHPIKHLF_01923	3.61e-181	-	-	-	O	-	-	-	Thioredoxin
NHPIKHLF_01925	2.8e-285	rpfB	-	-	S	ko:K21688	-	ko00000	G5
NHPIKHLF_01926	7.89e-216	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHPIKHLF_01927	1.09e-225	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHPIKHLF_01928	3.57e-144	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
NHPIKHLF_01929	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
NHPIKHLF_01930	3.46e-217	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
NHPIKHLF_01931	0.0	-	-	-	-	-	-	-	-
NHPIKHLF_01932	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
NHPIKHLF_01933	1.04e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHPIKHLF_01934	2.35e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHPIKHLF_01935	2.2e-224	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
NHPIKHLF_01936	3.05e-160	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NHPIKHLF_01937	8.02e-119	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
NHPIKHLF_01938	1.02e-236	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
NHPIKHLF_01939	2.07e-73	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHPIKHLF_01940	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family