ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PNEKKDIO_00005 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_00006 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_00007 0.0 yycH - - S - - - protein conserved in bacteria
PNEKKDIO_00008 2.83e-199 yycI - - S - - - protein conserved in bacteria
PNEKKDIO_00009 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PNEKKDIO_00010 1.82e-276 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PNEKKDIO_00011 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
PNEKKDIO_00012 2.31e-98 - - - S - - - Peptidase propeptide and YPEB domain
PNEKKDIO_00013 3.51e-121 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_00014 1.06e-213 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PNEKKDIO_00015 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PNEKKDIO_00016 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
PNEKKDIO_00017 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PNEKKDIO_00018 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PNEKKDIO_00020 9.09e-241 - - - S - - - aspartate phosphatase
PNEKKDIO_00021 1.29e-111 yycN - - K - - - Acetyltransferase
PNEKKDIO_00022 1.38e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PNEKKDIO_00023 1.03e-264 yycP - - - - - - -
PNEKKDIO_00024 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
PNEKKDIO_00026 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PNEKKDIO_00027 2.72e-88 - - - - - - - -
PNEKKDIO_00029 2.89e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PNEKKDIO_00030 2.38e-90 - - - S - - - AIPR protein
PNEKKDIO_00031 5.01e-131 yhdJ 2.1.1.72 - L ko:K00571,ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
PNEKKDIO_00032 2.37e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
PNEKKDIO_00033 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
PNEKKDIO_00034 8.35e-24 - - - - - - - -
PNEKKDIO_00035 7.1e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00036 1.41e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00037 1.16e-17 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
PNEKKDIO_00038 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PNEKKDIO_00039 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
PNEKKDIO_00040 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
PNEKKDIO_00041 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PNEKKDIO_00042 2.91e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PNEKKDIO_00043 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PNEKKDIO_00044 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
PNEKKDIO_00045 4.04e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PNEKKDIO_00046 2.34e-241 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
PNEKKDIO_00047 5.87e-144 yxaC - - M - - - effector of murein hydrolase
PNEKKDIO_00048 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00049 8.67e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_00050 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PNEKKDIO_00051 5.56e-246 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
PNEKKDIO_00052 2.08e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
PNEKKDIO_00053 4.03e-99 yxaI - - S - - - membrane protein domain
PNEKKDIO_00054 5.61e-83 - - - S - - - Family of unknown function (DUF5391)
PNEKKDIO_00055 2.63e-137 yxaL - - S - - - PQQ-like domain
PNEKKDIO_00056 1.64e-67 yxaM - - U - - - MFS_1 like family
PNEKKDIO_00057 5.43e-180 yxaM - - U - - - MFS_1 like family
PNEKKDIO_00058 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PNEKKDIO_00059 8.99e-114 yxnB - - - - - - -
PNEKKDIO_00060 1.49e-58 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
PNEKKDIO_00061 1.76e-175 yxbB - - Q - - - Met-10+ like-protein
PNEKKDIO_00062 4.71e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
PNEKKDIO_00063 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
PNEKKDIO_00064 4.85e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PNEKKDIO_00065 5.12e-266 yxbF - - K - - - Bacterial regulatory proteins, tetR family
PNEKKDIO_00066 4.85e-192 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_00068 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
PNEKKDIO_00069 2.4e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_00070 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
PNEKKDIO_00072 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
PNEKKDIO_00073 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PNEKKDIO_00074 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00075 2.84e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PNEKKDIO_00076 8.29e-226 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PNEKKDIO_00077 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PNEKKDIO_00078 1.18e-220 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PNEKKDIO_00079 5.7e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
PNEKKDIO_00080 8.95e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PNEKKDIO_00081 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
PNEKKDIO_00082 5.39e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PNEKKDIO_00083 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PNEKKDIO_00084 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_00085 1.05e-228 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_00086 7.72e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00087 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PNEKKDIO_00088 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
PNEKKDIO_00089 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PNEKKDIO_00090 1.41e-31 - - - - - - - -
PNEKKDIO_00091 7.57e-28 yxeD - - - - - - -
PNEKKDIO_00092 7.32e-42 yxeE - - - - - - -
PNEKKDIO_00095 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
PNEKKDIO_00096 2.92e-232 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PNEKKDIO_00097 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_00098 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_00099 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PNEKKDIO_00100 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PNEKKDIO_00101 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00102 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PNEKKDIO_00103 9.34e-317 yxeQ - - S - - - MmgE/PrpD family
PNEKKDIO_00104 4.04e-232 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
PNEKKDIO_00105 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
PNEKKDIO_00106 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PNEKKDIO_00107 1.96e-148 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PNEKKDIO_00108 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PNEKKDIO_00109 1.64e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
PNEKKDIO_00110 4.73e-305 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PNEKKDIO_00111 5.43e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PNEKKDIO_00113 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PNEKKDIO_00114 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PNEKKDIO_00115 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PNEKKDIO_00117 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PNEKKDIO_00119 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00120 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PNEKKDIO_00121 9.93e-94 yxiE - - T - - - Belongs to the universal stress protein A family
PNEKKDIO_00122 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
PNEKKDIO_00123 1.24e-113 - - - - - - - -
PNEKKDIO_00125 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
PNEKKDIO_00126 2.2e-28 - - - - - - - -
PNEKKDIO_00127 4.88e-209 yxxF - - EG - - - EamA-like transporter family
PNEKKDIO_00128 0.0 wapA - - M - - - COG3209 Rhs family protein
PNEKKDIO_00132 2.69e-55 yxiG - - - - - - -
PNEKKDIO_00133 4.83e-26 - - - - - - - -
PNEKKDIO_00134 1.49e-79 - - - - - - - -
PNEKKDIO_00135 1.86e-70 yxiI - - S - - - Protein of unknown function (DUF2716)
PNEKKDIO_00136 1.59e-55 yxiJ - - S - - - YxiJ-like protein
PNEKKDIO_00139 5.59e-271 - - - E - - - GDSL-like Lipase/Acylhydrolase
PNEKKDIO_00140 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PNEKKDIO_00141 6.57e-293 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
PNEKKDIO_00142 5.09e-141 - - - - - - - -
PNEKKDIO_00143 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PNEKKDIO_00144 3.06e-184 bglS - - M - - - licheninase activity
PNEKKDIO_00145 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PNEKKDIO_00146 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PNEKKDIO_00147 2.28e-63 yxiS - - - - - - -
PNEKKDIO_00148 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
PNEKKDIO_00149 2.98e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PNEKKDIO_00150 8.45e-202 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
PNEKKDIO_00151 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
PNEKKDIO_00152 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PNEKKDIO_00153 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PNEKKDIO_00154 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PNEKKDIO_00155 8.59e-266 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PNEKKDIO_00156 5.01e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PNEKKDIO_00157 1.43e-111 yxjI - - S - - - LURP-one-related
PNEKKDIO_00160 6.38e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PNEKKDIO_00161 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
PNEKKDIO_00162 1.87e-256 - - - T - - - Signal transduction histidine kinase
PNEKKDIO_00163 6.31e-90 - - - S - - - Protein of unknown function (DUF1453)
PNEKKDIO_00164 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PNEKKDIO_00165 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
PNEKKDIO_00166 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNEKKDIO_00167 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00168 5.53e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
PNEKKDIO_00169 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_00170 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
PNEKKDIO_00172 0.0 - - - O - - - Peptidase family M48
PNEKKDIO_00173 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
PNEKKDIO_00174 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PNEKKDIO_00175 8.19e-244 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
PNEKKDIO_00176 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
PNEKKDIO_00177 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
PNEKKDIO_00178 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PNEKKDIO_00179 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
PNEKKDIO_00180 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00181 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
PNEKKDIO_00182 1.75e-43 - - - - - - - -
PNEKKDIO_00183 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
PNEKKDIO_00184 2.35e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00185 1.88e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PNEKKDIO_00186 1.13e-270 yxlH - - EGP - - - Major Facilitator Superfamily
PNEKKDIO_00187 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PNEKKDIO_00188 1.87e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PNEKKDIO_00189 8.94e-28 yxzF - - - - - - -
PNEKKDIO_00190 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PNEKKDIO_00191 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
PNEKKDIO_00192 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNEKKDIO_00193 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00194 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PNEKKDIO_00195 2.52e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PNEKKDIO_00196 2.39e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_00197 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PNEKKDIO_00198 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_00199 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
PNEKKDIO_00200 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_00201 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PNEKKDIO_00202 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PNEKKDIO_00203 2.27e-164 - - - EGP - - - Permeases of the major facilitator superfamily
PNEKKDIO_00204 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
PNEKKDIO_00205 4.12e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
PNEKKDIO_00206 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
PNEKKDIO_00207 3.15e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PNEKKDIO_00208 2.52e-114 ywaE - - K - - - Transcriptional regulator
PNEKKDIO_00209 2.11e-159 ywaF - - S - - - Integral membrane protein
PNEKKDIO_00210 3.11e-215 gspA - - M - - - General stress
PNEKKDIO_00211 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PNEKKDIO_00212 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00213 8.55e-46 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PNEKKDIO_00214 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
PNEKKDIO_00215 8.59e-167 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNEKKDIO_00216 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PNEKKDIO_00217 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNEKKDIO_00218 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNEKKDIO_00219 1.33e-25 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PNEKKDIO_00220 5.84e-20 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PNEKKDIO_00221 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
PNEKKDIO_00222 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
PNEKKDIO_00223 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PNEKKDIO_00224 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
PNEKKDIO_00225 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PNEKKDIO_00226 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00227 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
PNEKKDIO_00228 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
PNEKKDIO_00229 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
PNEKKDIO_00231 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
PNEKKDIO_00232 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PNEKKDIO_00233 7e-91 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PNEKKDIO_00234 6.2e-271 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PNEKKDIO_00235 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PNEKKDIO_00236 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
PNEKKDIO_00237 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
PNEKKDIO_00238 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PNEKKDIO_00239 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PNEKKDIO_00240 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
PNEKKDIO_00241 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00242 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00243 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PNEKKDIO_00244 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
PNEKKDIO_00245 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PNEKKDIO_00246 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PNEKKDIO_00247 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PNEKKDIO_00249 1.01e-184 ysnF - - S - - - protein conserved in bacteria
PNEKKDIO_00250 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
PNEKKDIO_00252 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PNEKKDIO_00253 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PNEKKDIO_00254 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PNEKKDIO_00255 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PNEKKDIO_00256 6.1e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PNEKKDIO_00257 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PNEKKDIO_00258 7.31e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PNEKKDIO_00259 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
PNEKKDIO_00260 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PNEKKDIO_00261 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PNEKKDIO_00262 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
PNEKKDIO_00263 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PNEKKDIO_00264 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PNEKKDIO_00265 8.23e-117 ysxD - - - - - - -
PNEKKDIO_00266 2.26e-314 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PNEKKDIO_00267 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
PNEKKDIO_00268 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PNEKKDIO_00269 6.12e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PNEKKDIO_00270 8.71e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
PNEKKDIO_00271 4.11e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PNEKKDIO_00272 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
PNEKKDIO_00273 3.4e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PNEKKDIO_00274 1.53e-35 - - - - - - - -
PNEKKDIO_00275 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PNEKKDIO_00276 1.29e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PNEKKDIO_00277 8e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PNEKKDIO_00278 7.4e-212 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
PNEKKDIO_00279 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
PNEKKDIO_00280 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PNEKKDIO_00281 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
PNEKKDIO_00282 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PNEKKDIO_00283 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
PNEKKDIO_00284 2.05e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PNEKKDIO_00285 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PNEKKDIO_00286 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PNEKKDIO_00287 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
PNEKKDIO_00288 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PNEKKDIO_00289 1.27e-72 ysxB - - J ko:K07584 - ko00000 ribosomal protein
PNEKKDIO_00290 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PNEKKDIO_00291 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
PNEKKDIO_00292 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PNEKKDIO_00293 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
PNEKKDIO_00294 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PNEKKDIO_00295 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PNEKKDIO_00296 8.59e-293 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PNEKKDIO_00297 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
PNEKKDIO_00298 6.71e-207 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
PNEKKDIO_00299 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PNEKKDIO_00300 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
PNEKKDIO_00301 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PNEKKDIO_00302 8.27e-163 yebC - - K - - - transcriptional regulatory protein
PNEKKDIO_00303 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
PNEKKDIO_00305 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
PNEKKDIO_00307 2.32e-152 yrzF - - T - - - serine threonine protein kinase
PNEKKDIO_00308 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
PNEKKDIO_00309 0.0 csbX - - EGP - - - the major facilitator superfamily
PNEKKDIO_00310 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
PNEKKDIO_00311 5e-73 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PNEKKDIO_00312 9.58e-37 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PNEKKDIO_00313 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PNEKKDIO_00314 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
PNEKKDIO_00315 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PNEKKDIO_00316 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PNEKKDIO_00317 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
PNEKKDIO_00318 1.03e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
PNEKKDIO_00319 3.49e-14 yrbG - - S - - - membrane
PNEKKDIO_00320 9.63e-102 yrbG - - S - - - membrane
PNEKKDIO_00321 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_00322 1.59e-64 yrzD - - S - - - Post-transcriptional regulator
PNEKKDIO_00323 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PNEKKDIO_00324 1.53e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PNEKKDIO_00325 6.19e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
PNEKKDIO_00326 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PNEKKDIO_00327 1.03e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PNEKKDIO_00328 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PNEKKDIO_00329 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PNEKKDIO_00330 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
PNEKKDIO_00332 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PNEKKDIO_00333 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PNEKKDIO_00334 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PNEKKDIO_00335 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PNEKKDIO_00336 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00337 1.09e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PNEKKDIO_00338 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PNEKKDIO_00339 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
PNEKKDIO_00340 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PNEKKDIO_00341 1.23e-108 yrrD - - S - - - protein conserved in bacteria
PNEKKDIO_00342 8.4e-42 yrzR - - - - - - -
PNEKKDIO_00343 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
PNEKKDIO_00344 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PNEKKDIO_00345 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PNEKKDIO_00346 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PNEKKDIO_00347 5.42e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PNEKKDIO_00348 1.41e-42 yrrI - - S - - - AI-2E family transporter
PNEKKDIO_00349 3.32e-176 yrrI - - S - - - AI-2E family transporter
PNEKKDIO_00350 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PNEKKDIO_00351 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
PNEKKDIO_00352 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PNEKKDIO_00353 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
PNEKKDIO_00354 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PNEKKDIO_00355 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
PNEKKDIO_00356 1.09e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PNEKKDIO_00357 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
PNEKKDIO_00358 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PNEKKDIO_00359 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PNEKKDIO_00360 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
PNEKKDIO_00361 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
PNEKKDIO_00362 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
PNEKKDIO_00363 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
PNEKKDIO_00364 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PNEKKDIO_00365 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
PNEKKDIO_00366 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PNEKKDIO_00367 6.93e-49 yrhC - - S - - - YrhC-like protein
PNEKKDIO_00368 3.96e-77 yrhD - - S - - - Protein of unknown function (DUF1641)
PNEKKDIO_00369 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PNEKKDIO_00370 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
PNEKKDIO_00372 5.62e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
PNEKKDIO_00374 1.06e-54 yrhH - - Q - - - methyltransferase
PNEKKDIO_00375 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
PNEKKDIO_00376 3.25e-129 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PNEKKDIO_00377 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PNEKKDIO_00378 2.67e-62 yrhK - - S - - - YrhK-like protein
PNEKKDIO_00379 0.0 oatA - - I - - - Acyltransferase family
PNEKKDIO_00380 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
PNEKKDIO_00381 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00382 1.14e-191 yrhO - - K - - - Archaeal transcriptional regulator TrmB
PNEKKDIO_00383 9.34e-136 yrhP - - E - - - LysE type translocator
PNEKKDIO_00384 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_00385 0.0 levR - - K - - - PTS system fructose IIA component
PNEKKDIO_00386 2.18e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PNEKKDIO_00387 1.13e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
PNEKKDIO_00388 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PNEKKDIO_00389 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PNEKKDIO_00390 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PNEKKDIO_00391 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PNEKKDIO_00392 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
PNEKKDIO_00393 1.02e-38 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
PNEKKDIO_00394 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
PNEKKDIO_00395 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
PNEKKDIO_00396 6.11e-36 yraE - - - ko:K06440 - ko00000 -
PNEKKDIO_00397 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PNEKKDIO_00398 9.61e-84 yraF - - M - - - Spore coat protein
PNEKKDIO_00399 1.2e-49 yraG - - - ko:K06440 - ko00000 -
PNEKKDIO_00400 5.45e-86 - - - E - - - Glyoxalase-like domain
PNEKKDIO_00402 2.92e-81 - - - T - - - sh3 domain protein
PNEKKDIO_00403 4.65e-80 - - - T - - - sh3 domain protein
PNEKKDIO_00404 1.35e-197 - - - S - - - Alpha beta hydrolase
PNEKKDIO_00405 3.86e-53 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_00406 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PNEKKDIO_00407 5.95e-263 yraM - - S - - - PrpF protein
PNEKKDIO_00408 2.97e-210 yraN - - K - - - Transcriptional regulator
PNEKKDIO_00409 1.07e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PNEKKDIO_00410 6.96e-239 yrpG - - C - - - Aldo/keto reductase family
PNEKKDIO_00411 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00412 6.26e-168 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
PNEKKDIO_00414 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PNEKKDIO_00415 1.7e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
PNEKKDIO_00416 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PNEKKDIO_00417 1.27e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
PNEKKDIO_00419 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNEKKDIO_00420 2.79e-102 ygaO - - - - - - -
PNEKKDIO_00421 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00423 5.51e-147 yhzB - - S - - - B3/4 domain
PNEKKDIO_00424 8.1e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PNEKKDIO_00425 2.28e-224 yhbB - - S - - - Putative amidase domain
PNEKKDIO_00426 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PNEKKDIO_00427 2.29e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
PNEKKDIO_00428 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PNEKKDIO_00429 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PNEKKDIO_00430 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
PNEKKDIO_00431 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
PNEKKDIO_00433 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
PNEKKDIO_00434 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
PNEKKDIO_00435 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
PNEKKDIO_00436 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
PNEKKDIO_00437 3.95e-59 yhcC - - - - - - -
PNEKKDIO_00440 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00441 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00442 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00443 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PNEKKDIO_00444 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PNEKKDIO_00445 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PNEKKDIO_00446 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
PNEKKDIO_00447 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNEKKDIO_00448 1.13e-70 yhcM - - - - - - -
PNEKKDIO_00449 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PNEKKDIO_00450 8e-227 yhcP - - - - - - -
PNEKKDIO_00451 9.74e-146 yhcQ - - M - - - Spore coat protein
PNEKKDIO_00452 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PNEKKDIO_00453 1.18e-117 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PNEKKDIO_00454 2.18e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PNEKKDIO_00455 4.99e-88 yhcU - - S - - - Family of unknown function (DUF5365)
PNEKKDIO_00456 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
PNEKKDIO_00457 1.45e-153 yhcW - - S ko:K07025 - ko00000 hydrolase
PNEKKDIO_00458 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PNEKKDIO_00459 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PNEKKDIO_00460 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PNEKKDIO_00461 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PNEKKDIO_00462 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PNEKKDIO_00463 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PNEKKDIO_00464 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PNEKKDIO_00465 4.03e-12 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_00466 7.68e-218 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_00467 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_00468 1.63e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
PNEKKDIO_00469 1.65e-51 yhdB - - S - - - YhdB-like protein
PNEKKDIO_00470 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
PNEKKDIO_00471 3.25e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PNEKKDIO_00472 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
PNEKKDIO_00473 7.16e-305 ygxB - - M - - - Conserved TM helix
PNEKKDIO_00474 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
PNEKKDIO_00475 2.97e-227 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PNEKKDIO_00476 1.78e-81 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PNEKKDIO_00477 3.37e-10 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PNEKKDIO_00478 4.18e-159 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PNEKKDIO_00479 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00480 9.13e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PNEKKDIO_00481 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_00482 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
PNEKKDIO_00483 1.43e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PNEKKDIO_00484 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_00485 2.91e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_00486 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
PNEKKDIO_00487 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
PNEKKDIO_00488 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00489 1.93e-243 yhdN - - C - - - Aldo keto reductase
PNEKKDIO_00490 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PNEKKDIO_00491 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PNEKKDIO_00492 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
PNEKKDIO_00493 1.63e-280 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PNEKKDIO_00494 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
PNEKKDIO_00495 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNEKKDIO_00496 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PNEKKDIO_00497 8.67e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PNEKKDIO_00498 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
PNEKKDIO_00499 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
PNEKKDIO_00500 1.9e-176 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PNEKKDIO_00501 5.24e-196 nodB1 - - G - - - deacetylase
PNEKKDIO_00502 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PNEKKDIO_00503 2.18e-304 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PNEKKDIO_00504 1.1e-108 nhaX - - T - - - Belongs to the universal stress protein A family
PNEKKDIO_00505 5.37e-34 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_00506 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_00507 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_00508 3.31e-143 yheG - - GM - - - NAD(P)H-binding
PNEKKDIO_00509 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PNEKKDIO_00510 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
PNEKKDIO_00511 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
PNEKKDIO_00512 1.6e-274 yheC - - HJ - - - YheC/D like ATP-grasp
PNEKKDIO_00513 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
PNEKKDIO_00514 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
PNEKKDIO_00515 2.99e-195 yhaZ - - L - - - DNA alkylation repair enzyme
PNEKKDIO_00516 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
PNEKKDIO_00517 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
PNEKKDIO_00518 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
PNEKKDIO_00519 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PNEKKDIO_00521 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
PNEKKDIO_00522 2.29e-36 - - - S - - - YhzD-like protein
PNEKKDIO_00523 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00524 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
PNEKKDIO_00525 4.01e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
PNEKKDIO_00526 0.0 yhaN - - L - - - AAA domain
PNEKKDIO_00527 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
PNEKKDIO_00528 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
PNEKKDIO_00529 6.2e-51 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PNEKKDIO_00530 7.03e-93 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PNEKKDIO_00531 1.4e-116 yhaK - - S - - - Putative zincin peptidase
PNEKKDIO_00532 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
PNEKKDIO_00533 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
PNEKKDIO_00534 1.74e-54 yhaH - - S - - - YtxH-like protein
PNEKKDIO_00535 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
PNEKKDIO_00536 3.05e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PNEKKDIO_00537 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PNEKKDIO_00538 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
PNEKKDIO_00539 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PNEKKDIO_00540 1.67e-160 ecsC - - S - - - EcsC protein family
PNEKKDIO_00541 3.63e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PNEKKDIO_00542 9.42e-313 yhfA - - C - - - membrane
PNEKKDIO_00543 9.1e-43 - - - C - - - Rubrerythrin
PNEKKDIO_00544 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PNEKKDIO_00545 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PNEKKDIO_00546 1.3e-239 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PNEKKDIO_00547 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PNEKKDIO_00548 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PNEKKDIO_00549 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_00550 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
PNEKKDIO_00551 7.21e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PNEKKDIO_00552 7.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
PNEKKDIO_00553 1.55e-252 yhfE - - G - - - peptidase M42
PNEKKDIO_00554 1.53e-93 - - - S - - - ASCH
PNEKKDIO_00555 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNEKKDIO_00556 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PNEKKDIO_00557 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PNEKKDIO_00558 1.23e-142 yhfK - - GM - - - NmrA-like family
PNEKKDIO_00559 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PNEKKDIO_00560 6.55e-84 yhfM - - - - - - -
PNEKKDIO_00561 9.64e-308 yhfN - - O - - - Peptidase M48
PNEKKDIO_00562 1.2e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PNEKKDIO_00563 1.86e-103 - - - K - - - acetyltransferase
PNEKKDIO_00564 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
PNEKKDIO_00565 2.27e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PNEKKDIO_00566 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
PNEKKDIO_00567 7.05e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PNEKKDIO_00568 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PNEKKDIO_00569 1.21e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PNEKKDIO_00570 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
PNEKKDIO_00571 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PNEKKDIO_00572 4.15e-67 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_00573 4.26e-124 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_00574 8.22e-39 yhzC - - S - - - IDEAL
PNEKKDIO_00575 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
PNEKKDIO_00576 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_00577 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
PNEKKDIO_00578 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNEKKDIO_00579 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
PNEKKDIO_00580 4.13e-78 yhjD - - - - - - -
PNEKKDIO_00581 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
PNEKKDIO_00582 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PNEKKDIO_00583 0.0 yhjG - - CH - - - FAD binding domain
PNEKKDIO_00584 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00585 2.57e-272 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
PNEKKDIO_00586 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PNEKKDIO_00587 2.16e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
PNEKKDIO_00588 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PNEKKDIO_00589 8.8e-239 yhjM - - K - - - Transcriptional regulator
PNEKKDIO_00590 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
PNEKKDIO_00591 1.11e-266 - - - EGP - - - Transmembrane secretion effector
PNEKKDIO_00592 4.01e-90 - - - S - - - AAA domain
PNEKKDIO_00593 9e-32 - - - - - - - -
PNEKKDIO_00594 7.43e-58 - - - K - - - MarR family
PNEKKDIO_00595 6.85e-67 yckD - - S - - - Protein of unknown function (DUF2680)
PNEKKDIO_00596 9.49e-98 yckC - - S - - - membrane
PNEKKDIO_00598 1.53e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PNEKKDIO_00599 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PNEKKDIO_00600 1.6e-289 yciC - - S - - - GTPases (G3E family)
PNEKKDIO_00601 1.47e-131 - - - M - - - ErfK YbiS YcfS YnhG
PNEKKDIO_00602 3.36e-219 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
PNEKKDIO_00603 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PNEKKDIO_00604 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
PNEKKDIO_00605 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PNEKKDIO_00606 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PNEKKDIO_00607 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
PNEKKDIO_00608 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PNEKKDIO_00609 2.25e-240 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PNEKKDIO_00610 3.52e-70 ycgS - - I - - - alpha/beta hydrolase fold
PNEKKDIO_00611 9.42e-53 ycgS - - I - - - alpha/beta hydrolase fold
PNEKKDIO_00612 6.9e-184 ycgR - - S ko:K07089 - ko00000 permeases
PNEKKDIO_00613 1.56e-194 ycgQ - - S ko:K08986 - ko00000 membrane
PNEKKDIO_00614 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
PNEKKDIO_00615 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNEKKDIO_00616 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PNEKKDIO_00617 7.33e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PNEKKDIO_00618 2.13e-184 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
PNEKKDIO_00619 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PNEKKDIO_00620 1.14e-227 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
PNEKKDIO_00621 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
PNEKKDIO_00622 2.12e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PNEKKDIO_00624 3.61e-138 tmrB - - S - - - AAA domain
PNEKKDIO_00625 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PNEKKDIO_00626 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
PNEKKDIO_00627 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_00628 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PNEKKDIO_00629 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
PNEKKDIO_00630 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00631 0.0 mdr - - EGP - - - the major facilitator superfamily
PNEKKDIO_00632 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PNEKKDIO_00633 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PNEKKDIO_00634 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
PNEKKDIO_00635 3.17e-104 ycgB - - - - - - -
PNEKKDIO_00636 0.0 ycgA - - S - - - Membrane
PNEKKDIO_00637 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
PNEKKDIO_00638 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PNEKKDIO_00639 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PNEKKDIO_00640 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PNEKKDIO_00641 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PNEKKDIO_00642 1.07e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
PNEKKDIO_00643 2.7e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
PNEKKDIO_00644 2.96e-245 yceH - - P - - - Belongs to the TelA family
PNEKKDIO_00645 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
PNEKKDIO_00646 1.37e-174 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
PNEKKDIO_00647 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PNEKKDIO_00648 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PNEKKDIO_00649 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
PNEKKDIO_00650 5.95e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_00651 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PNEKKDIO_00652 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PNEKKDIO_00653 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PNEKKDIO_00654 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PNEKKDIO_00655 3.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_00656 6.72e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
PNEKKDIO_00657 4.57e-124 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PNEKKDIO_00658 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00659 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_00660 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
PNEKKDIO_00661 2.38e-222 yccK - - C - - - Aldo keto reductase
PNEKKDIO_00662 1.55e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PNEKKDIO_00663 2.86e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PNEKKDIO_00664 3.44e-44 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PNEKKDIO_00665 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PNEKKDIO_00666 1.58e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PNEKKDIO_00667 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
PNEKKDIO_00668 1.14e-73 - - - S - - - RDD family
PNEKKDIO_00669 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PNEKKDIO_00670 3.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PNEKKDIO_00671 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PNEKKDIO_00672 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
PNEKKDIO_00673 2.16e-262 ycbU - - E - - - Selenocysteine lyase
PNEKKDIO_00674 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PNEKKDIO_00675 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PNEKKDIO_00676 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PNEKKDIO_00677 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
PNEKKDIO_00678 6.13e-91 ycbR - - T - - - vWA found in TerF C terminus
PNEKKDIO_00679 2.72e-67 ycbR - - T - - - vWA found in TerF C terminus
PNEKKDIO_00680 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PNEKKDIO_00681 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
PNEKKDIO_00682 4.25e-150 - - - S - - - ABC-2 family transporter protein
PNEKKDIO_00683 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00684 6.48e-216 ycbM - - T - - - Histidine kinase
PNEKKDIO_00685 3.18e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_00686 5.9e-143 eamA1 - - EG - - - spore germination
PNEKKDIO_00687 6.24e-61 eamA1 - - EG - - - spore germination
PNEKKDIO_00688 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
PNEKKDIO_00689 8.62e-223 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
PNEKKDIO_00690 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PNEKKDIO_00691 3.26e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
PNEKKDIO_00692 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PNEKKDIO_00693 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_00694 6.17e-255 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00695 3.09e-68 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00696 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
PNEKKDIO_00697 7.01e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
PNEKKDIO_00698 3.4e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_00699 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PNEKKDIO_00700 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PNEKKDIO_00701 3.04e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
PNEKKDIO_00702 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PNEKKDIO_00703 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PNEKKDIO_00705 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PNEKKDIO_00706 1.05e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PNEKKDIO_00707 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00708 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNEKKDIO_00709 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PNEKKDIO_00710 1.24e-09 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
PNEKKDIO_00711 1.58e-59 ybfN - - - - - - -
PNEKKDIO_00712 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PNEKKDIO_00713 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
PNEKKDIO_00714 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PNEKKDIO_00715 1.53e-211 - - - S - - - Alpha/beta hydrolase family
PNEKKDIO_00717 1.44e-229 mpr - - M - - - Belongs to the peptidase S1B family
PNEKKDIO_00718 2.18e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PNEKKDIO_00719 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
PNEKKDIO_00720 6.15e-207 ybfH - - EG - - - EamA-like transporter family
PNEKKDIO_00721 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
PNEKKDIO_00723 6.47e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_00724 2.87e-216 ybfA - - K - - - FR47-like protein
PNEKKDIO_00725 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
PNEKKDIO_00726 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
PNEKKDIO_00727 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
PNEKKDIO_00728 0.0 ybeC - - E - - - amino acid
PNEKKDIO_00729 4.33e-34 ybeC - - E - - - amino acid
PNEKKDIO_00730 1.11e-54 ybyB - - - - - - -
PNEKKDIO_00731 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
PNEKKDIO_00732 4.09e-186 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
PNEKKDIO_00733 4.02e-40 ybxH - - S - - - Family of unknown function (DUF5370)
PNEKKDIO_00734 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
PNEKKDIO_00735 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_00736 1.55e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
PNEKKDIO_00737 3.67e-193 ybdN - - - - - - -
PNEKKDIO_00738 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PNEKKDIO_00739 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
PNEKKDIO_00740 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
PNEKKDIO_00741 1.82e-229 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PNEKKDIO_00742 7.97e-73 - - - - - - - -
PNEKKDIO_00743 1.09e-256 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
PNEKKDIO_00744 9.45e-67 - - - K - - - Helix-turn-helix domain
PNEKKDIO_00745 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
PNEKKDIO_00746 3.24e-63 - - - - - - - -
PNEKKDIO_00748 3.3e-119 ybcF - - P - - - carbonic anhydrase
PNEKKDIO_00749 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
PNEKKDIO_00750 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PNEKKDIO_00751 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PNEKKDIO_00752 1.07e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
PNEKKDIO_00753 3.02e-226 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PNEKKDIO_00754 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PNEKKDIO_00755 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PNEKKDIO_00756 1.04e-264 yetA - - - - - - -
PNEKKDIO_00757 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PNEKKDIO_00758 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PNEKKDIO_00759 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_00760 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PNEKKDIO_00761 1.49e-156 yetF - - S - - - membrane
PNEKKDIO_00762 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
PNEKKDIO_00763 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_00764 9.79e-45 - - - - - - - -
PNEKKDIO_00765 2.52e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PNEKKDIO_00766 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
PNEKKDIO_00767 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
PNEKKDIO_00768 7.35e-203 - - - EG - - - EamA-like transporter family
PNEKKDIO_00769 2.35e-69 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00770 8.81e-19 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_00771 4.77e-270 yetM - - CH - - - FAD binding domain
PNEKKDIO_00772 1.75e-254 yetN - - S - - - Protein of unknown function (DUF3900)
PNEKKDIO_00773 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PNEKKDIO_00774 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PNEKKDIO_00775 1.46e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
PNEKKDIO_00776 2.77e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
PNEKKDIO_00777 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
PNEKKDIO_00778 9.92e-286 yfnE - - S - - - Glycosyltransferase like family 2
PNEKKDIO_00779 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
PNEKKDIO_00780 1.78e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_00781 1.56e-169 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PNEKKDIO_00782 6.88e-312 yfnA - - E ko:K03294 - ko00000 amino acid
PNEKKDIO_00783 9.47e-17 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00784 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_00785 5.14e-161 yfmS - - NT - - - chemotaxis protein
PNEKKDIO_00786 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PNEKKDIO_00787 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
PNEKKDIO_00788 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
PNEKKDIO_00789 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
PNEKKDIO_00790 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PNEKKDIO_00791 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
PNEKKDIO_00792 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
PNEKKDIO_00793 1.71e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PNEKKDIO_00794 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PNEKKDIO_00795 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_00796 7.82e-219 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_00797 2.74e-59 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PNEKKDIO_00798 7.26e-94 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PNEKKDIO_00799 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
PNEKKDIO_00800 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
PNEKKDIO_00801 4.06e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PNEKKDIO_00802 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PNEKKDIO_00803 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PNEKKDIO_00804 3.26e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PNEKKDIO_00805 1.09e-227 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
PNEKKDIO_00806 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PNEKKDIO_00807 4.87e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PNEKKDIO_00808 6.53e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PNEKKDIO_00809 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PNEKKDIO_00810 1.98e-156 yflK - - S - - - protein conserved in bacteria
PNEKKDIO_00811 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
PNEKKDIO_00812 6.9e-27 yflI - - - - - - -
PNEKKDIO_00813 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
PNEKKDIO_00814 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PNEKKDIO_00815 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PNEKKDIO_00816 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PNEKKDIO_00817 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
PNEKKDIO_00818 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
PNEKKDIO_00819 3.61e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PNEKKDIO_00820 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00821 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PNEKKDIO_00822 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
PNEKKDIO_00823 6.16e-160 frp - - C - - - nitroreductase
PNEKKDIO_00824 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PNEKKDIO_00825 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PNEKKDIO_00826 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_00827 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
PNEKKDIO_00828 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PNEKKDIO_00829 1.03e-66 yfkI - - S - - - gas vesicle protein
PNEKKDIO_00830 1.57e-165 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PNEKKDIO_00831 2.74e-11 - - - - - - - -
PNEKKDIO_00832 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_00833 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
PNEKKDIO_00834 3.69e-189 yfkD - - S - - - YfkD-like protein
PNEKKDIO_00835 2.57e-190 yfkC - - M - - - Mechanosensitive ion channel
PNEKKDIO_00836 1.69e-281 yfkA - - S - - - YfkB-like domain
PNEKKDIO_00837 3.26e-36 yfjT - - - - - - -
PNEKKDIO_00838 6.15e-190 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
PNEKKDIO_00839 3.96e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PNEKKDIO_00840 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
PNEKKDIO_00841 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PNEKKDIO_00842 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNEKKDIO_00843 3.04e-59 - - - S - - - YfzA-like protein
PNEKKDIO_00844 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PNEKKDIO_00845 4.92e-104 yfjM - - S - - - Psort location Cytoplasmic, score
PNEKKDIO_00847 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PNEKKDIO_00848 4.37e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PNEKKDIO_00849 9.43e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PNEKKDIO_00850 5.86e-132 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PNEKKDIO_00851 4.12e-173 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PNEKKDIO_00852 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
PNEKKDIO_00853 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
PNEKKDIO_00854 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
PNEKKDIO_00855 3.2e-102 - - - S - - - Family of unknown function (DUF5381)
PNEKKDIO_00856 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
PNEKKDIO_00857 4.15e-184 yfjC - - - - - - -
PNEKKDIO_00858 9.2e-269 yfjB - - - - - - -
PNEKKDIO_00859 4.6e-60 yfjA - - S - - - Belongs to the WXG100 family
PNEKKDIO_00860 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PNEKKDIO_00861 4.27e-178 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PNEKKDIO_00862 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_00863 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
PNEKKDIO_00864 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_00865 3.34e-83 yfiD3 - - S - - - DoxX
PNEKKDIO_00866 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PNEKKDIO_00868 2.42e-272 baeS - - T - - - Histidine kinase
PNEKKDIO_00869 2.03e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
PNEKKDIO_00870 2.64e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_00871 2.53e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PNEKKDIO_00872 3.29e-260 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PNEKKDIO_00873 1.89e-128 padR - - K - - - transcriptional
PNEKKDIO_00874 4.78e-61 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PNEKKDIO_00875 1.19e-40 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PNEKKDIO_00876 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PNEKKDIO_00877 4e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
PNEKKDIO_00878 0.0 yfiU - - EGP - - - the major facilitator superfamily
PNEKKDIO_00879 2.11e-103 yfiV - - K - - - transcriptional
PNEKKDIO_00880 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PNEKKDIO_00881 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PNEKKDIO_00882 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_00883 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_00884 2.97e-212 yfhB - - S - - - PhzF family
PNEKKDIO_00885 1.17e-137 yfhC - - C - - - nitroreductase
PNEKKDIO_00886 8.86e-35 yfhD - - S - - - YfhD-like protein
PNEKKDIO_00888 3.24e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
PNEKKDIO_00889 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PNEKKDIO_00890 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
PNEKKDIO_00892 2.45e-268 yfhI - - EGP - - - -transporter
PNEKKDIO_00893 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
PNEKKDIO_00894 8.43e-37 yfhJ - - S - - - WVELL protein
PNEKKDIO_00895 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
PNEKKDIO_00896 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
PNEKKDIO_00897 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
PNEKKDIO_00898 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_00899 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PNEKKDIO_00900 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
PNEKKDIO_00901 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
PNEKKDIO_00902 1.73e-48 yfhS - - - - - - -
PNEKKDIO_00903 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_00904 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
PNEKKDIO_00905 2.01e-49 ygaB - - S - - - YgaB-like protein
PNEKKDIO_00906 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PNEKKDIO_00907 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
PNEKKDIO_00908 1.87e-238 ygaE - - S - - - Membrane
PNEKKDIO_00909 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PNEKKDIO_00910 8.36e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
PNEKKDIO_00911 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PNEKKDIO_00912 5.46e-74 ygzB - - S - - - UPF0295 protein
PNEKKDIO_00913 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
PNEKKDIO_00914 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PNEKKDIO_00915 2.68e-90 ylxW - - S - - - protein conserved in bacteria
PNEKKDIO_00916 4.91e-140 ylxX - - S - - - protein conserved in bacteria
PNEKKDIO_00917 5.37e-76 sbp - - S - - - small basic protein
PNEKKDIO_00918 4.01e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PNEKKDIO_00919 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PNEKKDIO_00920 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
PNEKKDIO_00921 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PNEKKDIO_00922 3.41e-31 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_00923 3.98e-111 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_00924 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_00925 1.05e-162 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PNEKKDIO_00926 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
PNEKKDIO_00927 1.46e-50 ylmC - - S - - - sporulation protein
PNEKKDIO_00928 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
PNEKKDIO_00929 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PNEKKDIO_00930 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PNEKKDIO_00931 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
PNEKKDIO_00932 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
PNEKKDIO_00933 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PNEKKDIO_00934 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PNEKKDIO_00935 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
PNEKKDIO_00936 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PNEKKDIO_00937 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PNEKKDIO_00938 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PNEKKDIO_00939 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
PNEKKDIO_00940 9.92e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PNEKKDIO_00941 2.91e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PNEKKDIO_00942 5.34e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PNEKKDIO_00943 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
PNEKKDIO_00944 9.12e-36 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PNEKKDIO_00945 1.41e-137 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PNEKKDIO_00946 8.96e-223 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PNEKKDIO_00947 4.3e-72 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PNEKKDIO_00948 1.14e-67 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PNEKKDIO_00949 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PNEKKDIO_00951 1.2e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PNEKKDIO_00952 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
PNEKKDIO_00953 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PNEKKDIO_00954 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PNEKKDIO_00955 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PNEKKDIO_00956 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
PNEKKDIO_00957 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
PNEKKDIO_00958 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PNEKKDIO_00959 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
PNEKKDIO_00960 3.42e-201 yloC - - S - - - stress-induced protein
PNEKKDIO_00961 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
PNEKKDIO_00962 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PNEKKDIO_00963 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PNEKKDIO_00964 2.43e-284 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PNEKKDIO_00965 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PNEKKDIO_00966 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PNEKKDIO_00967 1.09e-176 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PNEKKDIO_00968 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PNEKKDIO_00969 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PNEKKDIO_00970 4.13e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PNEKKDIO_00971 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PNEKKDIO_00972 1.86e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PNEKKDIO_00973 1.01e-117 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PNEKKDIO_00974 4.47e-25 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PNEKKDIO_00975 3e-38 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PNEKKDIO_00976 1.31e-100 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PNEKKDIO_00977 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PNEKKDIO_00978 3.65e-78 yloU - - S - - - protein conserved in bacteria
PNEKKDIO_00979 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PNEKKDIO_00980 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PNEKKDIO_00981 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PNEKKDIO_00982 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PNEKKDIO_00983 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PNEKKDIO_00984 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PNEKKDIO_00985 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PNEKKDIO_00986 4.55e-20 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PNEKKDIO_00987 7.36e-116 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PNEKKDIO_00988 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PNEKKDIO_00989 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PNEKKDIO_00990 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PNEKKDIO_00991 6.75e-125 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PNEKKDIO_00992 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PNEKKDIO_00993 1.67e-114 - - - - - - - -
PNEKKDIO_00994 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PNEKKDIO_00995 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PNEKKDIO_00996 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PNEKKDIO_00997 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PNEKKDIO_00998 9.77e-80 ylqD - - S - - - YlqD protein
PNEKKDIO_00999 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PNEKKDIO_01000 6.9e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PNEKKDIO_01001 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PNEKKDIO_01002 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PNEKKDIO_01003 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PNEKKDIO_01004 0.0 ylqG - - - - - - -
PNEKKDIO_01005 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
PNEKKDIO_01006 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PNEKKDIO_01007 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PNEKKDIO_01008 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
PNEKKDIO_01009 1.24e-49 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PNEKKDIO_01010 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PNEKKDIO_01011 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PNEKKDIO_01012 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
PNEKKDIO_01013 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PNEKKDIO_01014 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PNEKKDIO_01015 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PNEKKDIO_01016 2.84e-20 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PNEKKDIO_01017 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
PNEKKDIO_01018 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
PNEKKDIO_01019 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
PNEKKDIO_01020 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PNEKKDIO_01021 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
PNEKKDIO_01022 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PNEKKDIO_01023 3.93e-12 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PNEKKDIO_01024 3.91e-48 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PNEKKDIO_01025 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
PNEKKDIO_01026 2.87e-308 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
PNEKKDIO_01027 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
PNEKKDIO_01028 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
PNEKKDIO_01029 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
PNEKKDIO_01030 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PNEKKDIO_01031 7.96e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PNEKKDIO_01032 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
PNEKKDIO_01033 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
PNEKKDIO_01034 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
PNEKKDIO_01035 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
PNEKKDIO_01036 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
PNEKKDIO_01037 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PNEKKDIO_01038 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PNEKKDIO_01039 4.52e-248 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
PNEKKDIO_01040 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
PNEKKDIO_01041 2.12e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PNEKKDIO_01042 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
PNEKKDIO_01043 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
PNEKKDIO_01044 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PNEKKDIO_01045 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PNEKKDIO_01046 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_01047 2.81e-100 ylxL - - - - - - -
PNEKKDIO_01048 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PNEKKDIO_01049 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PNEKKDIO_01050 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PNEKKDIO_01051 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PNEKKDIO_01052 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PNEKKDIO_01053 1.8e-14 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PNEKKDIO_01054 1.11e-151 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PNEKKDIO_01055 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PNEKKDIO_01056 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PNEKKDIO_01057 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PNEKKDIO_01058 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNEKKDIO_01059 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PNEKKDIO_01060 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PNEKKDIO_01061 1.66e-36 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
PNEKKDIO_01062 6.16e-63 ylxQ - - J - - - ribosomal protein
PNEKKDIO_01063 5.41e-24 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PNEKKDIO_01064 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PNEKKDIO_01065 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PNEKKDIO_01067 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PNEKKDIO_01068 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PNEKKDIO_01069 8.03e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
PNEKKDIO_01070 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNEKKDIO_01071 6.32e-170 ywmB - - S - - - TATA-box binding
PNEKKDIO_01072 1.85e-44 ywzB - - S - - - membrane
PNEKKDIO_01073 7.16e-114 ywmA - - - - - - -
PNEKKDIO_01074 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PNEKKDIO_01075 3.63e-188 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PNEKKDIO_01076 7.96e-134 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PNEKKDIO_01077 9.01e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PNEKKDIO_01078 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PNEKKDIO_01079 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNEKKDIO_01080 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PNEKKDIO_01081 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PNEKKDIO_01082 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PNEKKDIO_01083 2.23e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
PNEKKDIO_01084 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PNEKKDIO_01085 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PNEKKDIO_01086 1.01e-122 ywlG - - S - - - Belongs to the UPF0340 family
PNEKKDIO_01087 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
PNEKKDIO_01088 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PNEKKDIO_01089 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
PNEKKDIO_01090 3.12e-209 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PNEKKDIO_01091 5.08e-30 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PNEKKDIO_01092 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
PNEKKDIO_01093 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
PNEKKDIO_01094 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PNEKKDIO_01096 1.74e-194 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PNEKKDIO_01097 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PNEKKDIO_01098 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_01099 1.21e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PNEKKDIO_01100 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PNEKKDIO_01101 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PNEKKDIO_01102 4.93e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PNEKKDIO_01103 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PNEKKDIO_01104 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PNEKKDIO_01105 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
PNEKKDIO_01106 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PNEKKDIO_01107 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PNEKKDIO_01108 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
PNEKKDIO_01109 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
PNEKKDIO_01110 2.24e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
PNEKKDIO_01111 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PNEKKDIO_01112 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PNEKKDIO_01113 2.86e-267 acdA - - I - - - acyl-CoA dehydrogenase
PNEKKDIO_01114 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PNEKKDIO_01115 3.38e-75 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PNEKKDIO_01116 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PNEKKDIO_01117 2.32e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PNEKKDIO_01118 1.32e-57 ywjC - - - - - - -
PNEKKDIO_01119 1.12e-100 ywjB - - H - - - RibD C-terminal domain
PNEKKDIO_01120 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
PNEKKDIO_01121 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNEKKDIO_01122 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
PNEKKDIO_01123 5.59e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
PNEKKDIO_01124 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
PNEKKDIO_01125 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PNEKKDIO_01126 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
PNEKKDIO_01127 7.49e-179 ywiC - - S - - - YwiC-like protein
PNEKKDIO_01128 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
PNEKKDIO_01129 4.81e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PNEKKDIO_01130 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PNEKKDIO_01131 4.64e-96 ywiB - - S - - - protein conserved in bacteria
PNEKKDIO_01132 3.71e-12 - - - S - - - Bacteriocin subtilosin A
PNEKKDIO_01133 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
PNEKKDIO_01135 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PNEKKDIO_01136 1.39e-296 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
PNEKKDIO_01137 1.4e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
PNEKKDIO_01138 5.85e-316 - - - L - - - Peptidase, M16
PNEKKDIO_01140 8.17e-316 ywhL - - CO - - - amine dehydrogenase activity
PNEKKDIO_01141 1.85e-288 ywhK - - CO - - - amine dehydrogenase activity
PNEKKDIO_01142 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PNEKKDIO_01145 1.3e-10 - - - - - - - -
PNEKKDIO_01148 1.51e-57 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PNEKKDIO_01150 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PNEKKDIO_01151 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PNEKKDIO_01152 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PNEKKDIO_01153 5.29e-121 ywhD - - S - - - YwhD family
PNEKKDIO_01154 3.29e-154 ywhC - - S - - - Peptidase family M50
PNEKKDIO_01155 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
PNEKKDIO_01156 1.76e-94 ywhA - - K - - - Transcriptional regulator
PNEKKDIO_01157 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PNEKKDIO_01159 1.41e-302 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
PNEKKDIO_01160 1.28e-102 yffB - - K - - - Transcriptional regulator
PNEKKDIO_01161 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
PNEKKDIO_01162 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
PNEKKDIO_01163 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
PNEKKDIO_01164 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
PNEKKDIO_01165 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
PNEKKDIO_01166 6.16e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PNEKKDIO_01167 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_01168 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
PNEKKDIO_01169 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
PNEKKDIO_01170 3.23e-174 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_01171 1.82e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PNEKKDIO_01172 7.55e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PNEKKDIO_01173 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PNEKKDIO_01174 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_01175 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PNEKKDIO_01176 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PNEKKDIO_01177 1.89e-275 ywfA - - EGP - - - -transporter
PNEKKDIO_01178 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PNEKKDIO_01179 1.81e-311 rocB - - E - - - arginine degradation protein
PNEKKDIO_01180 5.71e-42 rocB - - E - - - arginine degradation protein
PNEKKDIO_01181 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PNEKKDIO_01182 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PNEKKDIO_01183 3.7e-101 - - - - - - - -
PNEKKDIO_01184 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
PNEKKDIO_01185 1.92e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PNEKKDIO_01186 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PNEKKDIO_01187 2.5e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PNEKKDIO_01188 3.46e-241 spsG - - M - - - Spore Coat
PNEKKDIO_01189 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
PNEKKDIO_01190 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
PNEKKDIO_01191 1.16e-207 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
PNEKKDIO_01192 1.07e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PNEKKDIO_01193 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
PNEKKDIO_01194 8.08e-187 spsA - - M - - - Spore Coat
PNEKKDIO_01195 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PNEKKDIO_01196 1.59e-78 ywdK - - S - - - small membrane protein
PNEKKDIO_01197 2.17e-302 ywdJ - - F - - - Xanthine uracil
PNEKKDIO_01198 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
PNEKKDIO_01199 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PNEKKDIO_01200 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PNEKKDIO_01201 1.57e-190 ywdF - - S - - - Glycosyltransferase like family 2
PNEKKDIO_01203 2.51e-145 ywdD - - - - - - -
PNEKKDIO_01204 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
PNEKKDIO_01205 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PNEKKDIO_01206 6.19e-39 ywdA - - - - - - -
PNEKKDIO_01207 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PNEKKDIO_01208 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_01209 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
PNEKKDIO_01210 2.6e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PNEKKDIO_01212 2.34e-139 yvgT - - S - - - membrane
PNEKKDIO_01213 5.7e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
PNEKKDIO_01214 3.45e-137 bdbD - - O - - - Thioredoxin
PNEKKDIO_01215 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PNEKKDIO_01216 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PNEKKDIO_01217 1.78e-81 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PNEKKDIO_01218 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
PNEKKDIO_01219 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
PNEKKDIO_01220 3.08e-251 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PNEKKDIO_01221 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PNEKKDIO_01222 0.0 - - - S - - - Fusaric acid resistance protein-like
PNEKKDIO_01223 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
PNEKKDIO_01224 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PNEKKDIO_01225 4.23e-129 - - - K - - - Bacterial regulatory proteins, tetR family
PNEKKDIO_01226 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_01228 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PNEKKDIO_01229 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PNEKKDIO_01230 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
PNEKKDIO_01231 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PNEKKDIO_01232 4.04e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
PNEKKDIO_01233 3.44e-48 yvzC - - K - - - transcriptional
PNEKKDIO_01234 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PNEKKDIO_01235 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PNEKKDIO_01236 3.85e-72 yvaP - - K - - - transcriptional
PNEKKDIO_01237 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_01238 7.18e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PNEKKDIO_01239 3.77e-217 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PNEKKDIO_01240 6.3e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PNEKKDIO_01241 1.48e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PNEKKDIO_01242 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PNEKKDIO_01243 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PNEKKDIO_01244 1.74e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PNEKKDIO_01245 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PNEKKDIO_01246 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PNEKKDIO_01247 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PNEKKDIO_01248 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PNEKKDIO_01249 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
PNEKKDIO_01250 1.13e-156 yvbI - - M - - - Membrane
PNEKKDIO_01251 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PNEKKDIO_01252 6.87e-106 yvbK - - K - - - acetyltransferase
PNEKKDIO_01253 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PNEKKDIO_01254 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
PNEKKDIO_01255 6.09e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PNEKKDIO_01256 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PNEKKDIO_01257 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PNEKKDIO_01258 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PNEKKDIO_01259 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_01260 1.24e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
PNEKKDIO_01261 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_01262 4.9e-206 yvbU - - K - - - Transcriptional regulator
PNEKKDIO_01263 1.2e-185 yvbV - - EG - - - EamA-like transporter family
PNEKKDIO_01264 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_01265 7.67e-252 - - - S - - - Glycosyl hydrolase
PNEKKDIO_01266 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PNEKKDIO_01267 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PNEKKDIO_01268 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PNEKKDIO_01269 3.58e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_01270 1.88e-252 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_01271 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PNEKKDIO_01272 1.7e-208 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PNEKKDIO_01273 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
PNEKKDIO_01274 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
PNEKKDIO_01275 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
PNEKKDIO_01276 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
PNEKKDIO_01277 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PNEKKDIO_01278 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PNEKKDIO_01279 4.7e-287 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PNEKKDIO_01280 1.51e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_01281 1.99e-81 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PNEKKDIO_01282 1.12e-50 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PNEKKDIO_01283 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PNEKKDIO_01284 4.96e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PNEKKDIO_01285 5.69e-44 yvfG - - S - - - YvfG protein
PNEKKDIO_01286 5.95e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
PNEKKDIO_01287 3.04e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PNEKKDIO_01288 2.45e-82 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PNEKKDIO_01289 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PNEKKDIO_01290 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_01291 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_01292 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
PNEKKDIO_01293 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PNEKKDIO_01294 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
PNEKKDIO_01295 1.8e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PNEKKDIO_01296 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_01297 1.4e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
PNEKKDIO_01298 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PNEKKDIO_01299 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PNEKKDIO_01300 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
PNEKKDIO_01301 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
PNEKKDIO_01302 9.03e-50 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PNEKKDIO_01303 4.15e-276 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PNEKKDIO_01305 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PNEKKDIO_01306 4.48e-96 - - - S - - - Protein of unknown function (DUF3237)
PNEKKDIO_01307 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PNEKKDIO_01308 0.0 pbpE - - V - - - Beta-lactamase
PNEKKDIO_01309 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
PNEKKDIO_01310 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PNEKKDIO_01311 0.0 ybeC - - E - - - amino acid
PNEKKDIO_01312 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
PNEKKDIO_01313 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PNEKKDIO_01314 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
PNEKKDIO_01315 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
PNEKKDIO_01316 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
PNEKKDIO_01317 1.99e-235 - - - S - - - Patatin-like phospholipase
PNEKKDIO_01319 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PNEKKDIO_01320 5.12e-145 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PNEKKDIO_01321 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PNEKKDIO_01322 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
PNEKKDIO_01323 1.08e-193 malA - - S - - - Protein of unknown function (DUF1189)
PNEKKDIO_01324 6.56e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PNEKKDIO_01325 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PNEKKDIO_01326 1.2e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PNEKKDIO_01327 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
PNEKKDIO_01328 6.1e-93 yvdE - - K - - - Transcriptional regulator
PNEKKDIO_01329 2.75e-117 yvdE - - K - - - Transcriptional regulator
PNEKKDIO_01330 1.54e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PNEKKDIO_01331 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
PNEKKDIO_01332 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PNEKKDIO_01333 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PNEKKDIO_01334 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEKKDIO_01335 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PNEKKDIO_01336 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_01337 2.28e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
PNEKKDIO_01338 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_01339 1.32e-43 - - - - - - - -
PNEKKDIO_01340 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
PNEKKDIO_01341 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
PNEKKDIO_01342 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PNEKKDIO_01343 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PNEKKDIO_01344 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PNEKKDIO_01345 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PNEKKDIO_01346 9.69e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PNEKKDIO_01347 6.03e-116 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
PNEKKDIO_01348 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PNEKKDIO_01351 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
PNEKKDIO_01352 6.72e-247 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PNEKKDIO_01353 3.3e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PNEKKDIO_01354 1.21e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
PNEKKDIO_01355 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
PNEKKDIO_01356 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PNEKKDIO_01357 3.23e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNEKKDIO_01358 5.86e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_01359 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_01360 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
PNEKKDIO_01361 1.4e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
PNEKKDIO_01362 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PNEKKDIO_01363 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
PNEKKDIO_01365 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PNEKKDIO_01366 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PNEKKDIO_01367 7.71e-166 - - - - - - - -
PNEKKDIO_01368 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PNEKKDIO_01369 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
PNEKKDIO_01370 5.24e-158 ydhC - - K - - - FCD
PNEKKDIO_01371 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
PNEKKDIO_01372 2.43e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PNEKKDIO_01373 3.29e-90 - - - K - - - Winged helix DNA-binding domain
PNEKKDIO_01374 1.84e-146 ydgI - - C - - - nitroreductase
PNEKKDIO_01375 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
PNEKKDIO_01376 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_01377 5.09e-119 - - - S - - - DinB family
PNEKKDIO_01378 7.57e-173 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_01379 6.47e-89 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_01380 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
PNEKKDIO_01381 2.19e-131 - - - G - - - Xylose isomerase-like TIM barrel
PNEKKDIO_01382 1.37e-239 xylT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_01383 1.16e-151 - - - K - - - helix_turn _helix lactose operon repressor
PNEKKDIO_01384 5.97e-167 idhA 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
PNEKKDIO_01385 5.66e-111 yycN - - K - - - Acetyltransferase
PNEKKDIO_01386 3.47e-71 - - - S - - - DoxX-like family
PNEKKDIO_01387 9.93e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
PNEKKDIO_01388 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
PNEKKDIO_01389 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
PNEKKDIO_01390 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PNEKKDIO_01391 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
PNEKKDIO_01392 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
PNEKKDIO_01394 5.33e-39 - - - - - - - -
PNEKKDIO_01395 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
PNEKKDIO_01396 3.11e-73 ydfQ - - CO - - - Thioredoxin
PNEKKDIO_01397 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
PNEKKDIO_01398 1.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PNEKKDIO_01399 1.64e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
PNEKKDIO_01400 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNEKKDIO_01401 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
PNEKKDIO_01402 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PNEKKDIO_01403 3e-220 - - - S - - - Alpha/beta hydrolase family
PNEKKDIO_01404 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
PNEKKDIO_01405 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_01406 8.43e-246 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_01408 1.15e-54 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PNEKKDIO_01409 3.03e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PNEKKDIO_01410 9.91e-150 ydfE - - S - - - Flavin reductase like domain
PNEKKDIO_01411 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_01412 5.89e-205 - - - EG - - - EamA-like transporter family
PNEKKDIO_01413 1.9e-189 - - - J - - - GNAT acetyltransferase
PNEKKDIO_01414 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PNEKKDIO_01415 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
PNEKKDIO_01416 2.16e-135 ydeS - - K - - - Transcriptional regulator
PNEKKDIO_01417 5.61e-257 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
PNEKKDIO_01418 2.87e-144 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
PNEKKDIO_01419 2.92e-90 ydeP - - K - - - Transcriptional regulator
PNEKKDIO_01420 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PNEKKDIO_01421 2.13e-74 - - - K - - - HxlR-like helix-turn-helix
PNEKKDIO_01422 1.17e-135 - - - S ko:K07002 - ko00000 Serine hydrolase
PNEKKDIO_01423 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
PNEKKDIO_01424 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_01425 4.66e-197 ydeK - - EG - - - -transporter
PNEKKDIO_01426 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
PNEKKDIO_01427 4.69e-19 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
PNEKKDIO_01428 1e-139 - - - - - - - -
PNEKKDIO_01429 4.53e-132 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
PNEKKDIO_01430 9.2e-70 ydeH - - - - - - -
PNEKKDIO_01431 6.28e-276 ydeG - - EGP - - - Major facilitator superfamily
PNEKKDIO_01432 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_01433 2.64e-209 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PNEKKDIO_01434 1.08e-218 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PNEKKDIO_01435 4.22e-211 - - - K - - - AraC-like ligand binding domain
PNEKKDIO_01436 5.63e-181 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PNEKKDIO_01437 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
PNEKKDIO_01438 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
PNEKKDIO_01439 1.86e-242 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PNEKKDIO_01440 1.54e-55 - - - - - - - -
PNEKKDIO_01441 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PNEKKDIO_01442 1.54e-126 - - - M - - - nucleic acid phosphodiester bond hydrolysis
PNEKKDIO_01443 3.12e-50 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
PNEKKDIO_01444 2.01e-58 - - - - - - - -
PNEKKDIO_01445 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
PNEKKDIO_01453 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PNEKKDIO_01454 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
PNEKKDIO_01455 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
PNEKKDIO_01456 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_01457 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PNEKKDIO_01458 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
PNEKKDIO_01459 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
PNEKKDIO_01460 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PNEKKDIO_01461 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
PNEKKDIO_01462 2.46e-183 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
PNEKKDIO_01463 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PNEKKDIO_01464 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PNEKKDIO_01465 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PNEKKDIO_01466 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
PNEKKDIO_01467 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PNEKKDIO_01468 4.04e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
PNEKKDIO_01469 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
PNEKKDIO_01470 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
PNEKKDIO_01471 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PNEKKDIO_01472 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PNEKKDIO_01473 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PNEKKDIO_01474 4.19e-75 ydbP - - CO - - - Thioredoxin
PNEKKDIO_01475 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNEKKDIO_01476 1.49e-26 - - - S - - - Fur-regulated basic protein B
PNEKKDIO_01477 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
PNEKKDIO_01478 9.32e-70 ydbL - - - - - - -
PNEKKDIO_01479 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PNEKKDIO_01480 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_01481 1.32e-230 ydbI - - S - - - AI-2E family transporter
PNEKKDIO_01482 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PNEKKDIO_01483 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PNEKKDIO_01484 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PNEKKDIO_01485 7.39e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PNEKKDIO_01486 1.29e-196 ydbD - - P ko:K07217 - ko00000 Catalase
PNEKKDIO_01487 3.13e-83 ydbC - - S - - - Domain of unknown function (DUF4937
PNEKKDIO_01488 7.58e-79 ydbB - - G - - - Cupin domain
PNEKKDIO_01489 1e-06 gsiB - - S ko:K06884 - ko00000 general stress protein
PNEKKDIO_01490 3.03e-50 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_01491 6.07e-49 - - - - - - - -
PNEKKDIO_01492 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PNEKKDIO_01493 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
PNEKKDIO_01496 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
PNEKKDIO_01497 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
PNEKKDIO_01498 9.3e-32 cotW - - - ko:K06341 - ko00000 -
PNEKKDIO_01499 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
PNEKKDIO_01500 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
PNEKKDIO_01501 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
PNEKKDIO_01502 1.65e-52 yjbX - - S - - - Spore coat protein
PNEKKDIO_01503 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PNEKKDIO_01504 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PNEKKDIO_01505 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PNEKKDIO_01506 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PNEKKDIO_01507 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
PNEKKDIO_01508 1.42e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
PNEKKDIO_01509 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
PNEKKDIO_01510 5.48e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PNEKKDIO_01511 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PNEKKDIO_01512 6.5e-162 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PNEKKDIO_01513 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PNEKKDIO_01514 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PNEKKDIO_01515 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
PNEKKDIO_01516 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
PNEKKDIO_01517 7.32e-130 yjbK - - S - - - protein conserved in bacteria
PNEKKDIO_01518 2.94e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_01519 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
PNEKKDIO_01520 5.78e-194 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PNEKKDIO_01522 3.44e-10 - - - - - - - -
PNEKKDIO_01523 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PNEKKDIO_01524 1.78e-281 coiA - - S ko:K06198 - ko00000 Competence protein
PNEKKDIO_01525 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PNEKKDIO_01526 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
PNEKKDIO_01527 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PNEKKDIO_01528 2.45e-63 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_01529 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
PNEKKDIO_01530 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_01531 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_01532 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_01533 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_01534 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PNEKKDIO_01535 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PNEKKDIO_01536 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
PNEKKDIO_01537 1.7e-207 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_01538 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_01539 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
PNEKKDIO_01540 6.93e-236 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_01541 1.02e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_01542 7.79e-192 yjaZ - - O - - - Zn-dependent protease
PNEKKDIO_01543 2.52e-301 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNEKKDIO_01544 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PNEKKDIO_01545 2.67e-38 yjzB - - - - - - -
PNEKKDIO_01546 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
PNEKKDIO_01547 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
PNEKKDIO_01548 6.08e-131 yjaV - - - - - - -
PNEKKDIO_01549 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
PNEKKDIO_01550 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
PNEKKDIO_01551 2.51e-39 yjzC - - S - - - YjzC-like protein
PNEKKDIO_01552 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PNEKKDIO_01553 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
PNEKKDIO_01554 8.11e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PNEKKDIO_01555 1.62e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PNEKKDIO_01556 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PNEKKDIO_01557 1.74e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PNEKKDIO_01558 1.18e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PNEKKDIO_01559 3.48e-59 yitZ - - G - - - Major Facilitator Superfamily
PNEKKDIO_01560 6.59e-34 yitZ - - G - - - Major Facilitator Superfamily
PNEKKDIO_01561 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
PNEKKDIO_01562 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
PNEKKDIO_01563 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
PNEKKDIO_01564 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PNEKKDIO_01565 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PNEKKDIO_01566 1.92e-08 - - - - - - - -
PNEKKDIO_01567 3.02e-36 - - - S - - - Protein of unknown function (DUF3813)
PNEKKDIO_01568 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
PNEKKDIO_01569 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PNEKKDIO_01570 3.72e-201 yitS - - S - - - protein conserved in bacteria
PNEKKDIO_01571 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PNEKKDIO_01572 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
PNEKKDIO_01573 5.86e-118 - - - - - - - -
PNEKKDIO_01574 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
PNEKKDIO_01575 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
PNEKKDIO_01576 1.17e-217 - - - - - - - -
PNEKKDIO_01577 4.16e-122 - - - - - - - -
PNEKKDIO_01578 9.21e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
PNEKKDIO_01579 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
PNEKKDIO_01580 8.93e-224 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PNEKKDIO_01581 1.34e-177 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PNEKKDIO_01582 1.46e-91 - - - S - - - Acetyltransferase (GNAT) domain
PNEKKDIO_01583 2.6e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
PNEKKDIO_01584 1.54e-54 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_01585 1.64e-214 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_01586 1.97e-279 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PNEKKDIO_01587 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PNEKKDIO_01588 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
PNEKKDIO_01589 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
PNEKKDIO_01590 2.15e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PNEKKDIO_01591 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PNEKKDIO_01592 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PNEKKDIO_01593 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PNEKKDIO_01594 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
PNEKKDIO_01595 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_01596 1.05e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
PNEKKDIO_01597 6.99e-120 yisT - - S - - - DinB family
PNEKKDIO_01598 1.73e-247 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PNEKKDIO_01599 1.06e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PNEKKDIO_01600 1.41e-207 yisR - - K - - - Transcriptional regulator
PNEKKDIO_01601 1.01e-310 yisQ - - V - - - Mate efflux family protein
PNEKKDIO_01602 4.6e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
PNEKKDIO_01603 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
PNEKKDIO_01604 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PNEKKDIO_01605 9.03e-133 yisN - - S - - - Protein of unknown function (DUF2777)
PNEKKDIO_01606 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PNEKKDIO_01607 1.02e-74 yisL - - S - - - UPF0344 protein
PNEKKDIO_01608 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PNEKKDIO_01609 2.2e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
PNEKKDIO_01610 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
PNEKKDIO_01611 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
PNEKKDIO_01612 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
PNEKKDIO_01613 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
PNEKKDIO_01614 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
PNEKKDIO_01615 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
PNEKKDIO_01616 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
PNEKKDIO_01617 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
PNEKKDIO_01618 3.92e-119 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PNEKKDIO_01619 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PNEKKDIO_01620 8.08e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PNEKKDIO_01621 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PNEKKDIO_01622 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
PNEKKDIO_01623 9.3e-102 yhjR - - S - - - Rubrerythrin
PNEKKDIO_01624 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
PNEKKDIO_01625 1.16e-154 - - - S - - - AAA domain
PNEKKDIO_01626 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PNEKKDIO_01627 4.78e-91 nin - - S - - - Competence protein J (ComJ)
PNEKKDIO_01628 1.13e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
PNEKKDIO_01629 1.76e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_01630 1.32e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PNEKKDIO_01631 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
PNEKKDIO_01632 1.74e-85 hxlR - - K - - - transcriptional
PNEKKDIO_01633 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_01634 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_01635 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
PNEKKDIO_01636 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
PNEKKDIO_01637 1.72e-285 - - - EGP - - - Major Facilitator Superfamily
PNEKKDIO_01639 1.18e-72 - - - S - - - YcxB-like protein
PNEKKDIO_01640 4.64e-205 ycxC - - EG - - - EamA-like transporter family
PNEKKDIO_01641 0.0 ycxD - - K - - - GntR family transcriptional regulator
PNEKKDIO_01642 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PNEKKDIO_01643 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
PNEKKDIO_01644 2.38e-170 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PNEKKDIO_01645 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PNEKKDIO_01646 4.82e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PNEKKDIO_01647 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
PNEKKDIO_01648 6.9e-128 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PNEKKDIO_01649 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PNEKKDIO_01650 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
PNEKKDIO_01651 3.05e-109 yclD - - - - - - -
PNEKKDIO_01652 1.58e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
PNEKKDIO_01653 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
PNEKKDIO_01654 0.0 yclG - - M - - - Pectate lyase superfamily protein
PNEKKDIO_01656 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PNEKKDIO_01657 4.83e-296 gerKC - - S ko:K06297 - ko00000 spore germination
PNEKKDIO_01658 1.33e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
PNEKKDIO_01659 1.18e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PNEKKDIO_01660 1.31e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
PNEKKDIO_01661 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_01662 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PNEKKDIO_01663 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PNEKKDIO_01664 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PNEKKDIO_01665 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PNEKKDIO_01666 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PNEKKDIO_01667 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_01668 4.06e-185 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_01669 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_01670 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
PNEKKDIO_01671 0.0 ycnB - - EGP - - - the major facilitator superfamily
PNEKKDIO_01672 1.76e-199 ycnC - - K - - - Transcriptional regulator
PNEKKDIO_01673 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PNEKKDIO_01674 1.68e-60 ycnE - - S - - - Monooxygenase
PNEKKDIO_01675 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PNEKKDIO_01676 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PNEKKDIO_01677 2.68e-310 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PNEKKDIO_01678 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PNEKKDIO_01679 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
PNEKKDIO_01680 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_01681 7.73e-132 ycnI - - S - - - protein conserved in bacteria
PNEKKDIO_01682 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
PNEKKDIO_01683 3.37e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PNEKKDIO_01684 9.44e-75 - - - - - - - -
PNEKKDIO_01685 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
PNEKKDIO_01686 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PNEKKDIO_01687 1.47e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
PNEKKDIO_01688 6.84e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
PNEKKDIO_01689 1.21e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PNEKKDIO_01690 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
PNEKKDIO_01691 9.34e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PNEKKDIO_01693 2.56e-141 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PNEKKDIO_01694 2.67e-21 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PNEKKDIO_01695 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
PNEKKDIO_01696 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
PNEKKDIO_01697 1.65e-188 ycsI - - S - - - Belongs to the D-glutamate cyclase family
PNEKKDIO_01698 4.84e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
PNEKKDIO_01699 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
PNEKKDIO_01700 2.2e-170 kipR - - K - - - Transcriptional regulator
PNEKKDIO_01701 2.42e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
PNEKKDIO_01703 7.67e-66 yczJ - - S - - - biosynthesis
PNEKKDIO_01704 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
PNEKKDIO_01705 8.25e-218 ycsN - - S - - - Oxidoreductase
PNEKKDIO_01706 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
PNEKKDIO_01707 0.0 ydaB - - IQ - - - acyl-CoA ligase
PNEKKDIO_01708 1e-127 ydaC - - Q - - - Methyltransferase domain
PNEKKDIO_01709 8.81e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_01710 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
PNEKKDIO_01711 5.85e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PNEKKDIO_01712 5.24e-101 ydaG - - S - - - general stress protein
PNEKKDIO_01713 8.86e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PNEKKDIO_01714 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
PNEKKDIO_01715 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PNEKKDIO_01716 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PNEKKDIO_01717 5.97e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
PNEKKDIO_01718 5.21e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
PNEKKDIO_01719 1.02e-305 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
PNEKKDIO_01720 8.82e-77 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
PNEKKDIO_01721 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
PNEKKDIO_01722 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
PNEKKDIO_01723 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PNEKKDIO_01724 1.51e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PNEKKDIO_01725 1.07e-81 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PNEKKDIO_01726 9.49e-145 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PNEKKDIO_01727 8.43e-282 pbpX - - V - - - Beta-lactamase
PNEKKDIO_01728 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PNEKKDIO_01729 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
PNEKKDIO_01730 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
PNEKKDIO_01731 3.38e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PNEKKDIO_01732 4.84e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PNEKKDIO_01733 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PNEKKDIO_01734 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PNEKKDIO_01735 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
PNEKKDIO_01736 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PNEKKDIO_01737 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PNEKKDIO_01738 1.98e-91 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PNEKKDIO_01739 3.7e-89 - - - S - - - Regulatory protein YrvL
PNEKKDIO_01741 6.55e-126 ymcC - - S - - - Membrane
PNEKKDIO_01742 2.94e-141 pksA - - K - - - Transcriptional regulator
PNEKKDIO_01743 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
PNEKKDIO_01744 5.32e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PNEKKDIO_01746 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
PNEKKDIO_01747 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PNEKKDIO_01748 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
PNEKKDIO_01749 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNEKKDIO_01750 6.55e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
PNEKKDIO_01751 3.95e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
PNEKKDIO_01752 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
PNEKKDIO_01753 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PNEKKDIO_01754 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PNEKKDIO_01755 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PNEKKDIO_01756 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PNEKKDIO_01757 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PNEKKDIO_01758 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
PNEKKDIO_01759 3.96e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PNEKKDIO_01760 8.03e-81 ymzB - - - - - - -
PNEKKDIO_01761 1.13e-208 - - - S - - - Metallo-beta-lactamase superfamily
PNEKKDIO_01762 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
PNEKKDIO_01764 3.96e-163 ymaC - - S - - - Replication protein
PNEKKDIO_01765 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
PNEKKDIO_01766 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
PNEKKDIO_01767 8.23e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PNEKKDIO_01769 5.41e-76 ymaF - - S - - - YmaF family
PNEKKDIO_01770 7.96e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PNEKKDIO_01771 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PNEKKDIO_01772 2.69e-30 - - - - - - - -
PNEKKDIO_01773 1.2e-30 ymzA - - - - - - -
PNEKKDIO_01774 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PNEKKDIO_01775 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEKKDIO_01776 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEKKDIO_01777 2.24e-141 - - - - - - - -
PNEKKDIO_01778 5.74e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PNEKKDIO_01779 1.66e-219 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PNEKKDIO_01780 1.05e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PNEKKDIO_01781 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PNEKKDIO_01782 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
PNEKKDIO_01783 1.11e-72 yknT - - - ko:K06437 - ko00000 -
PNEKKDIO_01784 1.08e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PNEKKDIO_01785 2.54e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PNEKKDIO_01786 2.48e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
PNEKKDIO_01787 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
PNEKKDIO_01788 4.99e-68 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
PNEKKDIO_01789 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PNEKKDIO_01790 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_01791 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PNEKKDIO_01792 1.6e-151 yknW - - S - - - Yip1 domain
PNEKKDIO_01793 1.84e-221 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PNEKKDIO_01794 1.51e-76 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_01795 9.39e-66 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_01796 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PNEKKDIO_01797 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_01798 8.21e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
PNEKKDIO_01799 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PNEKKDIO_01800 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PNEKKDIO_01801 5.43e-52 ykoA - - - - - - -
PNEKKDIO_01802 3.06e-197 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PNEKKDIO_01803 9.17e-151 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PNEKKDIO_01804 3.34e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PNEKKDIO_01805 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PNEKKDIO_01806 1.09e-18 - - - S - - - Uncharacterized protein YkpC
PNEKKDIO_01807 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
PNEKKDIO_01808 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
PNEKKDIO_01809 1.32e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PNEKKDIO_01810 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
PNEKKDIO_01811 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PNEKKDIO_01812 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PNEKKDIO_01813 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNEKKDIO_01814 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
PNEKKDIO_01815 1.18e-186 ykrA - - S - - - hydrolases of the HAD superfamily
PNEKKDIO_01816 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PNEKKDIO_01817 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PNEKKDIO_01818 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
PNEKKDIO_01819 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PNEKKDIO_01820 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PNEKKDIO_01821 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PNEKKDIO_01822 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PNEKKDIO_01823 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PNEKKDIO_01824 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
PNEKKDIO_01825 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
PNEKKDIO_01826 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
PNEKKDIO_01827 2.03e-35 ykzI - - - - - - -
PNEKKDIO_01828 3.18e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
PNEKKDIO_01829 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
PNEKKDIO_01830 1.37e-218 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PNEKKDIO_01831 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PNEKKDIO_01832 0.0 ylaA - - - - - - -
PNEKKDIO_01833 1.44e-56 ylaB - - - - - - -
PNEKKDIO_01834 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_01836 5.7e-56 ylaE - - - - - - -
PNEKKDIO_01837 1.56e-30 - - - S - - - Family of unknown function (DUF5325)
PNEKKDIO_01838 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PNEKKDIO_01839 4.4e-63 ylaH - - S - - - YlaH-like protein
PNEKKDIO_01840 8.92e-44 ylaI - - S - - - protein conserved in bacteria
PNEKKDIO_01841 6.99e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PNEKKDIO_01842 1.44e-67 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PNEKKDIO_01843 2.29e-199 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PNEKKDIO_01844 2.67e-111 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PNEKKDIO_01845 2.02e-218 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PNEKKDIO_01846 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
PNEKKDIO_01847 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PNEKKDIO_01848 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PNEKKDIO_01849 1.16e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PNEKKDIO_01850 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PNEKKDIO_01851 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PNEKKDIO_01852 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PNEKKDIO_01853 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PNEKKDIO_01854 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PNEKKDIO_01855 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
PNEKKDIO_01856 1.61e-81 ylbA - - S - - - YugN-like family
PNEKKDIO_01857 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
PNEKKDIO_01858 6.24e-256 ylbC - - S - - - protein with SCP PR1 domains
PNEKKDIO_01859 3.24e-89 ylbD - - S - - - Putative coat protein
PNEKKDIO_01860 1.73e-48 ylbE - - S - - - YlbE-like protein
PNEKKDIO_01861 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
PNEKKDIO_01862 5.1e-51 ylbG - - S - - - UPF0298 protein
PNEKKDIO_01863 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PNEKKDIO_01864 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PNEKKDIO_01865 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
PNEKKDIO_01866 1.48e-175 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PNEKKDIO_01867 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PNEKKDIO_01868 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
PNEKKDIO_01870 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PNEKKDIO_01871 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PNEKKDIO_01872 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PNEKKDIO_01873 1.33e-115 ylbP - - K - - - n-acetyltransferase
PNEKKDIO_01874 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PNEKKDIO_01875 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PNEKKDIO_01876 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PNEKKDIO_01877 1.36e-217 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PNEKKDIO_01878 3.42e-68 ftsL - - D - - - Essential cell division protein
PNEKKDIO_01879 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PNEKKDIO_01880 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
PNEKKDIO_01881 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PNEKKDIO_01882 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PNEKKDIO_01883 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PNEKKDIO_01884 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PNEKKDIO_01885 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PNEKKDIO_01886 9.18e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PNEKKDIO_01887 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PNEKKDIO_01890 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PNEKKDIO_01891 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
PNEKKDIO_01892 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
PNEKKDIO_01893 2.84e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PNEKKDIO_01894 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PNEKKDIO_01895 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
PNEKKDIO_01896 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PNEKKDIO_01897 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PNEKKDIO_01898 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PNEKKDIO_01899 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PNEKKDIO_01900 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
PNEKKDIO_01901 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PNEKKDIO_01902 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PNEKKDIO_01903 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PNEKKDIO_01904 2.22e-50 ydjC - - S - - - Abhydrolase domain containing 18
PNEKKDIO_01905 1.08e-141 ydjC - - S - - - alpha beta
PNEKKDIO_01906 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
PNEKKDIO_01907 3.55e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PNEKKDIO_01908 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
PNEKKDIO_01909 4.07e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PNEKKDIO_01910 9.24e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
PNEKKDIO_01911 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PNEKKDIO_01912 5.4e-175 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
PNEKKDIO_01913 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
PNEKKDIO_01914 1.87e-246 - - - S - - - Ion transport 2 domain protein
PNEKKDIO_01915 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_01916 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PNEKKDIO_01917 1.79e-84 ydjM - - M - - - Lytic transglycolase
PNEKKDIO_01918 1.05e-170 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
PNEKKDIO_01920 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
PNEKKDIO_01921 3.21e-205 - - - I - - - Alpha/beta hydrolase family
PNEKKDIO_01922 9.5e-185 yeaA - - S - - - Protein of unknown function (DUF4003)
PNEKKDIO_01923 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
PNEKKDIO_01924 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_01925 1.44e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PNEKKDIO_01926 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
PNEKKDIO_01927 1.15e-162 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PNEKKDIO_01928 2.04e-107 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PNEKKDIO_01929 6.58e-23 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PNEKKDIO_01930 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PNEKKDIO_01931 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PNEKKDIO_01932 6.85e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_01933 4.47e-312 - - - S - - - Domain of unknown function (DUF4179)
PNEKKDIO_01934 3.27e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PNEKKDIO_01935 5.85e-165 yebC - - M - - - Membrane
PNEKKDIO_01937 2.66e-120 yebE - - S - - - UPF0316 protein
PNEKKDIO_01938 3.13e-38 yebG - - S - - - NETI protein
PNEKKDIO_01939 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PNEKKDIO_01940 3.55e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PNEKKDIO_01941 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PNEKKDIO_01942 4.81e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PNEKKDIO_01943 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEKKDIO_01944 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEKKDIO_01945 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PNEKKDIO_01946 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PNEKKDIO_01947 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PNEKKDIO_01948 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PNEKKDIO_01949 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PNEKKDIO_01950 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PNEKKDIO_01951 1.06e-95 - - - K - - - helix_turn_helix ASNC type
PNEKKDIO_01952 3.21e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
PNEKKDIO_01953 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
PNEKKDIO_01954 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
PNEKKDIO_01955 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
PNEKKDIO_01956 6.27e-67 yerC - - S - - - protein conserved in bacteria
PNEKKDIO_01957 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
PNEKKDIO_01958 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PNEKKDIO_01959 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PNEKKDIO_01960 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PNEKKDIO_01961 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
PNEKKDIO_01962 7.33e-252 yerI - - S - - - homoserine kinase type II (protein kinase fold)
PNEKKDIO_01963 1.32e-159 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PNEKKDIO_01964 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNEKKDIO_01965 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNEKKDIO_01966 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PNEKKDIO_01967 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PNEKKDIO_01968 1.77e-178 yerO - - K - - - Transcriptional regulator
PNEKKDIO_01969 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PNEKKDIO_01970 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PNEKKDIO_01971 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PNEKKDIO_01972 1.12e-100 - - - K - - - Helix-turn-helix
PNEKKDIO_01973 2.26e-131 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PNEKKDIO_01974 1.28e-79 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PNEKKDIO_01975 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PNEKKDIO_01976 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PNEKKDIO_01977 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PNEKKDIO_01978 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
PNEKKDIO_01979 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
PNEKKDIO_01981 0.0 - - - L - - - AAA ATPase domain
PNEKKDIO_01982 1.78e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PNEKKDIO_01983 1.45e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_01984 3.35e-56 - - - - - - - -
PNEKKDIO_01986 1.36e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
PNEKKDIO_01987 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
PNEKKDIO_01988 1.29e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PNEKKDIO_01989 1.17e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PNEKKDIO_01990 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_01991 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PNEKKDIO_01992 2.74e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
PNEKKDIO_01993 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PNEKKDIO_01994 8.1e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_01995 6.53e-218 bsn - - L - - - Ribonuclease
PNEKKDIO_01996 2.05e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PNEKKDIO_01997 2.44e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PNEKKDIO_01999 1.47e-242 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PNEKKDIO_02000 6.18e-143 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
PNEKKDIO_02001 1.46e-136 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PNEKKDIO_02002 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PNEKKDIO_02003 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PNEKKDIO_02004 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PNEKKDIO_02005 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
PNEKKDIO_02006 6.71e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PNEKKDIO_02007 4.65e-295 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
PNEKKDIO_02008 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
PNEKKDIO_02009 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PNEKKDIO_02010 2.72e-82 yunG - - - - - - -
PNEKKDIO_02011 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
PNEKKDIO_02012 1.08e-179 yunE - - S ko:K07090 - ko00000 membrane transporter protein
PNEKKDIO_02013 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PNEKKDIO_02014 3.28e-63 yunC - - S - - - Domain of unknown function (DUF1805)
PNEKKDIO_02015 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
PNEKKDIO_02016 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
PNEKKDIO_02017 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PNEKKDIO_02018 1.29e-142 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PNEKKDIO_02019 3.2e-63 yutD - - S - - - protein conserved in bacteria
PNEKKDIO_02020 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
PNEKKDIO_02021 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PNEKKDIO_02022 3.34e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PNEKKDIO_02023 1.55e-253 yutH - - S - - - Spore coat protein
PNEKKDIO_02024 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PNEKKDIO_02025 2.2e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PNEKKDIO_02026 1.22e-219 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PNEKKDIO_02027 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
PNEKKDIO_02028 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
PNEKKDIO_02029 1.1e-73 yuzD - - S - - - protein conserved in bacteria
PNEKKDIO_02030 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PNEKKDIO_02031 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
PNEKKDIO_02032 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PNEKKDIO_02033 4.55e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PNEKKDIO_02034 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
PNEKKDIO_02036 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_02037 2.84e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
PNEKKDIO_02038 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PNEKKDIO_02040 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
PNEKKDIO_02041 8.3e-246 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PNEKKDIO_02042 5.3e-27 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PNEKKDIO_02043 9.78e-47 yuiB - - S - - - Putative membrane protein
PNEKKDIO_02044 1.1e-149 yuiC - - S - - - protein conserved in bacteria
PNEKKDIO_02045 6.78e-60 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PNEKKDIO_02046 5.69e-31 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PNEKKDIO_02047 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PNEKKDIO_02048 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
PNEKKDIO_02049 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
PNEKKDIO_02050 1.37e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
PNEKKDIO_02051 7.35e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
PNEKKDIO_02052 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_02053 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PNEKKDIO_02054 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
PNEKKDIO_02055 3.15e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
PNEKKDIO_02056 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_02057 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
PNEKKDIO_02058 4.88e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PNEKKDIO_02059 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PNEKKDIO_02060 2.96e-292 yukF - - QT - - - Transcriptional regulator
PNEKKDIO_02061 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
PNEKKDIO_02062 7.67e-56 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PNEKKDIO_02063 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_02064 4.7e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PNEKKDIO_02065 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNEKKDIO_02066 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PNEKKDIO_02067 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_02068 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
PNEKKDIO_02069 6.16e-165 yoxB - - - - - - -
PNEKKDIO_02070 3e-109 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PNEKKDIO_02071 2.95e-301 - - - S - - - Arylsulfotransferase (ASST)
PNEKKDIO_02072 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
PNEKKDIO_02073 1.24e-297 yoaB - - EGP - - - the major facilitator superfamily
PNEKKDIO_02074 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PNEKKDIO_02075 2.37e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEKKDIO_02076 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PNEKKDIO_02077 2.95e-44 yoaF - - - - - - -
PNEKKDIO_02079 1.46e-19 - - - - - - - -
PNEKKDIO_02080 2.27e-24 - - - S - - - Protein of unknown function (DUF4025)
PNEKKDIO_02081 8.71e-287 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
PNEKKDIO_02082 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
PNEKKDIO_02083 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
PNEKKDIO_02084 1.79e-145 yoaK - - S - - - Membrane
PNEKKDIO_02085 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
PNEKKDIO_02086 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PNEKKDIO_02088 3.54e-96 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PNEKKDIO_02089 1.22e-114 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PNEKKDIO_02092 1.22e-168 yoaP - - K - - - YoaP-like
PNEKKDIO_02093 3.94e-69 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
PNEKKDIO_02095 7.91e-115 - - - - - - - -
PNEKKDIO_02096 4.24e-217 yoaR - - V - - - vancomycin resistance protein
PNEKKDIO_02097 2.65e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
PNEKKDIO_02098 6.07e-49 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_02099 3.84e-189 yoaT - - S - - - Protein of unknown function (DUF817)
PNEKKDIO_02100 5.48e-202 yoaU - - K - - - LysR substrate binding domain
PNEKKDIO_02101 1.24e-199 yoaV - - EG - - - EamA-like transporter family
PNEKKDIO_02102 3.26e-101 yoaW - - - - - - -
PNEKKDIO_02103 2.27e-124 lin0465 - - S - - - DJ-1/PfpI family
PNEKKDIO_02104 1.21e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
PNEKKDIO_02107 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PNEKKDIO_02108 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PNEKKDIO_02109 2.11e-49 - - - S - - - TM2 domain
PNEKKDIO_02110 2.6e-11 - - - K - - - Helix-turn-helix
PNEKKDIO_02113 2.92e-63 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
PNEKKDIO_02120 2.36e-22 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PNEKKDIO_02121 5.14e-151 - - - - - - - -
PNEKKDIO_02122 2.72e-39 - - - O - - - Subtilase family
PNEKKDIO_02129 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
PNEKKDIO_02131 1.43e-80 yoqH - - M - - - LysM domain
PNEKKDIO_02135 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PNEKKDIO_02137 4.49e-100 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_02138 1.49e-42 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_02139 2.43e-26 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_02141 1.58e-59 - - - - - - - -
PNEKKDIO_02143 5.21e-26 - - - - - - - -
PNEKKDIO_02144 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PNEKKDIO_02145 1.13e-116 yokH - - G - - - SMI1 / KNR4 family
PNEKKDIO_02146 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
PNEKKDIO_02147 0.0 yobO - - M - - - Pectate lyase superfamily protein
PNEKKDIO_02148 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
PNEKKDIO_02149 4.48e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
PNEKKDIO_02150 5.06e-181 - - - J - - - FR47-like protein
PNEKKDIO_02151 3.09e-127 yobS - - K - - - Transcriptional regulator
PNEKKDIO_02152 7.76e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PNEKKDIO_02153 6.32e-114 - - - K - - - Bacterial transcription activator, effector binding domain
PNEKKDIO_02154 1.33e-225 yobV - - K - - - WYL domain
PNEKKDIO_02155 3.01e-120 yobW - - - - - - -
PNEKKDIO_02156 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
PNEKKDIO_02157 2.12e-155 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_02158 1.21e-97 yozB - - S ko:K08976 - ko00000 membrane
PNEKKDIO_02159 2.49e-183 - - - - - - - -
PNEKKDIO_02160 1.08e-121 yocC - - - - - - -
PNEKKDIO_02161 2.73e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
PNEKKDIO_02162 1.9e-256 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PNEKKDIO_02163 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_02164 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_02165 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
PNEKKDIO_02166 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PNEKKDIO_02167 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PNEKKDIO_02168 1.42e-107 yocK - - T - - - general stress protein
PNEKKDIO_02169 4.29e-70 yocL - - - - - - -
PNEKKDIO_02170 5.79e-43 - - - - - - - -
PNEKKDIO_02171 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PNEKKDIO_02172 2.94e-55 yozN - - - - - - -
PNEKKDIO_02173 1.83e-49 yocN - - - - - - -
PNEKKDIO_02174 2.17e-74 yozO - - S - - - Bacterial PH domain
PNEKKDIO_02176 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
PNEKKDIO_02177 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PNEKKDIO_02178 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PNEKKDIO_02179 9.26e-10 - - - S - - - Fur-regulated basic protein B
PNEKKDIO_02181 1.9e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
PNEKKDIO_02182 1.57e-20 yneP - - S ko:K07107 - ko00000,ko01000 thioesterase
PNEKKDIO_02183 1.28e-62 yneP - - S ko:K07107 - ko00000,ko01000 thioesterase
PNEKKDIO_02184 1.63e-71 yneQ - - - - - - -
PNEKKDIO_02185 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
PNEKKDIO_02186 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PNEKKDIO_02187 7e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PNEKKDIO_02188 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNEKKDIO_02189 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PNEKKDIO_02190 1.82e-18 - - - - - - - -
PNEKKDIO_02191 1.06e-75 ynfC - - - - - - -
PNEKKDIO_02192 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PNEKKDIO_02193 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
PNEKKDIO_02195 1.13e-304 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
PNEKKDIO_02196 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PNEKKDIO_02197 2.45e-103 yngA - - S - - - membrane
PNEKKDIO_02198 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PNEKKDIO_02199 3.44e-32 yngC - - S - - - membrane-associated protein
PNEKKDIO_02200 4.31e-71 yngC - - S - - - membrane-associated protein
PNEKKDIO_02201 9e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
PNEKKDIO_02202 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PNEKKDIO_02203 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
PNEKKDIO_02204 2.86e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
PNEKKDIO_02205 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
PNEKKDIO_02206 1.6e-228 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PNEKKDIO_02207 5.02e-39 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PNEKKDIO_02208 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PNEKKDIO_02209 1.26e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PNEKKDIO_02210 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
PNEKKDIO_02211 6.08e-84 yngL - - S - - - Protein of unknown function (DUF1360)
PNEKKDIO_02212 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
PNEKKDIO_02213 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_02214 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_02215 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_02216 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PNEKKDIO_02217 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PNEKKDIO_02218 1.16e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PNEKKDIO_02219 9.8e-313 yoeA - - V - - - MATE efflux family protein
PNEKKDIO_02220 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
PNEKKDIO_02222 1.14e-124 - - - L - - - Integrase
PNEKKDIO_02223 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
PNEKKDIO_02224 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PNEKKDIO_02225 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_02226 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PNEKKDIO_02227 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PNEKKDIO_02228 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PNEKKDIO_02229 4.53e-254 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PNEKKDIO_02230 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
PNEKKDIO_02231 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
PNEKKDIO_02232 1.26e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
PNEKKDIO_02233 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
PNEKKDIO_02234 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PNEKKDIO_02235 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
PNEKKDIO_02236 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PNEKKDIO_02237 4.74e-311 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PNEKKDIO_02238 6.43e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PNEKKDIO_02239 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PNEKKDIO_02240 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PNEKKDIO_02241 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
PNEKKDIO_02242 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PNEKKDIO_02243 6.98e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PNEKKDIO_02244 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
PNEKKDIO_02245 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
PNEKKDIO_02246 1.27e-59 ysdA - - S - - - Membrane
PNEKKDIO_02247 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PNEKKDIO_02248 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PNEKKDIO_02249 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PNEKKDIO_02251 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PNEKKDIO_02252 3.45e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PNEKKDIO_02253 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PNEKKDIO_02254 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_02255 4.68e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
PNEKKDIO_02256 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PNEKKDIO_02258 5.98e-206 ytxC - - S - - - YtxC-like family
PNEKKDIO_02259 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
PNEKKDIO_02260 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PNEKKDIO_02261 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
PNEKKDIO_02262 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PNEKKDIO_02263 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PNEKKDIO_02264 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PNEKKDIO_02265 9.85e-88 ytcD - - K - - - Transcriptional regulator
PNEKKDIO_02266 4.23e-186 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PNEKKDIO_02267 1.9e-47 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PNEKKDIO_02268 4.54e-205 ytbE - - S - - - reductase
PNEKKDIO_02269 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PNEKKDIO_02270 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
PNEKKDIO_02271 5.52e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PNEKKDIO_02272 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PNEKKDIO_02273 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
PNEKKDIO_02274 7.02e-170 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_02275 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
PNEKKDIO_02276 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
PNEKKDIO_02277 6.74e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PNEKKDIO_02278 1.56e-93 ytwI - - S - - - membrane
PNEKKDIO_02279 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
PNEKKDIO_02280 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
PNEKKDIO_02281 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PNEKKDIO_02282 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PNEKKDIO_02283 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PNEKKDIO_02284 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PNEKKDIO_02285 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PNEKKDIO_02286 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PNEKKDIO_02287 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
PNEKKDIO_02288 5.12e-112 ytrI - - - - - - -
PNEKKDIO_02289 1.15e-39 - - - - - - - -
PNEKKDIO_02290 5.04e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
PNEKKDIO_02291 2.15e-63 ytpI - - S - - - YtpI-like protein
PNEKKDIO_02292 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
PNEKKDIO_02293 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
PNEKKDIO_02294 5.28e-300 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PNEKKDIO_02295 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
PNEKKDIO_02296 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_02297 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
PNEKKDIO_02298 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_02299 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PNEKKDIO_02300 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_02301 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_02302 1.52e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PNEKKDIO_02303 5.37e-182 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PNEKKDIO_02304 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PNEKKDIO_02305 1.67e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
PNEKKDIO_02306 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
PNEKKDIO_02307 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_02309 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PNEKKDIO_02310 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PNEKKDIO_02311 2.33e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
PNEKKDIO_02312 1.52e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PNEKKDIO_02313 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PNEKKDIO_02314 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PNEKKDIO_02315 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
PNEKKDIO_02316 7.04e-112 ytfI - - S - - - Protein of unknown function (DUF2953)
PNEKKDIO_02317 2.41e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PNEKKDIO_02318 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PNEKKDIO_02319 3.64e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PNEKKDIO_02320 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PNEKKDIO_02321 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_02322 2.53e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
PNEKKDIO_02323 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PNEKKDIO_02324 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PNEKKDIO_02325 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
PNEKKDIO_02326 2.28e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PNEKKDIO_02327 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
PNEKKDIO_02328 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
PNEKKDIO_02329 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PNEKKDIO_02330 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PNEKKDIO_02331 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
PNEKKDIO_02332 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PNEKKDIO_02333 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_02334 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_02335 2.72e-104 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_02336 8.27e-252 rsiX - - - - - - -
PNEKKDIO_02337 4.11e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PNEKKDIO_02338 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PNEKKDIO_02339 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PNEKKDIO_02340 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
PNEKKDIO_02341 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
PNEKKDIO_02342 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PNEKKDIO_02343 1.02e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
PNEKKDIO_02344 2.05e-123 ypbE - - M - - - Lysin motif
PNEKKDIO_02345 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
PNEKKDIO_02346 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PNEKKDIO_02347 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PNEKKDIO_02348 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PNEKKDIO_02349 6.3e-225 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
PNEKKDIO_02350 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
PNEKKDIO_02351 1.57e-126 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
PNEKKDIO_02352 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
PNEKKDIO_02353 1.09e-142 ypfA - - M - - - Flagellar protein YcgR
PNEKKDIO_02354 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
PNEKKDIO_02355 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PNEKKDIO_02356 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PNEKKDIO_02357 3.28e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PNEKKDIO_02358 1.13e-11 - - - S - - - YpzI-like protein
PNEKKDIO_02359 6.43e-133 yphA - - - - - - -
PNEKKDIO_02360 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
PNEKKDIO_02361 8.69e-40 ypzH - - - - - - -
PNEKKDIO_02362 3.53e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PNEKKDIO_02363 4.05e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PNEKKDIO_02364 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
PNEKKDIO_02365 9.07e-178 yphF - - - - - - -
PNEKKDIO_02366 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PNEKKDIO_02367 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PNEKKDIO_02368 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PNEKKDIO_02369 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PNEKKDIO_02370 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PNEKKDIO_02371 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PNEKKDIO_02372 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PNEKKDIO_02373 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PNEKKDIO_02374 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PNEKKDIO_02375 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PNEKKDIO_02376 8.13e-263 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PNEKKDIO_02377 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PNEKKDIO_02378 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PNEKKDIO_02379 2.48e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PNEKKDIO_02380 1.2e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PNEKKDIO_02381 1.1e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PNEKKDIO_02382 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PNEKKDIO_02383 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PNEKKDIO_02384 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PNEKKDIO_02385 9.9e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PNEKKDIO_02386 1.92e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PNEKKDIO_02387 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
PNEKKDIO_02388 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
PNEKKDIO_02389 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
PNEKKDIO_02390 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
PNEKKDIO_02391 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
PNEKKDIO_02392 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
PNEKKDIO_02393 1.63e-125 ypjA - - S - - - membrane
PNEKKDIO_02394 6.84e-183 ypjB - - S - - - sporulation protein
PNEKKDIO_02395 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PNEKKDIO_02396 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
PNEKKDIO_02397 3.98e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PNEKKDIO_02398 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
PNEKKDIO_02399 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
PNEKKDIO_02400 7.01e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
PNEKKDIO_02401 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PNEKKDIO_02402 4e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PNEKKDIO_02403 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PNEKKDIO_02404 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PNEKKDIO_02405 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PNEKKDIO_02406 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PNEKKDIO_02407 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
PNEKKDIO_02408 2.66e-102 ypmB - - S - - - protein conserved in bacteria
PNEKKDIO_02409 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PNEKKDIO_02410 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
PNEKKDIO_02411 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
PNEKKDIO_02412 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PNEKKDIO_02413 1.43e-121 ypoC - - - - - - -
PNEKKDIO_02414 6.69e-53 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PNEKKDIO_02415 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PNEKKDIO_02416 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PNEKKDIO_02417 1.7e-92 yviE - - - - - - -
PNEKKDIO_02418 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
PNEKKDIO_02419 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
PNEKKDIO_02420 2.02e-101 yvyG - - NOU - - - FlgN protein
PNEKKDIO_02421 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
PNEKKDIO_02422 1.83e-96 yvyF - - S - - - flagellar protein
PNEKKDIO_02423 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
PNEKKDIO_02424 4.22e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
PNEKKDIO_02425 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PNEKKDIO_02426 2.15e-199 degV - - S - - - protein conserved in bacteria
PNEKKDIO_02427 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_02428 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PNEKKDIO_02429 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
PNEKKDIO_02430 3.81e-223 yvhJ - - K - - - Transcriptional regulator
PNEKKDIO_02431 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PNEKKDIO_02432 1.76e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
PNEKKDIO_02433 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PNEKKDIO_02434 1.02e-130 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
PNEKKDIO_02436 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
PNEKKDIO_02437 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PNEKKDIO_02438 3.42e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
PNEKKDIO_02439 4.22e-160 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_02440 3.97e-119 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_02441 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PNEKKDIO_02442 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PNEKKDIO_02443 0.0 lytB - - D - - - Stage II sporulation protein
PNEKKDIO_02444 3.26e-50 - - - - - - - -
PNEKKDIO_02445 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PNEKKDIO_02446 2.58e-275 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PNEKKDIO_02447 2.53e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PNEKKDIO_02448 9.11e-71 - - - - - - - -
PNEKKDIO_02449 9.69e-152 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PNEKKDIO_02450 7.99e-89 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PNEKKDIO_02451 1.82e-113 - - - M - - - Glycosyltransferase like family 2
PNEKKDIO_02452 1.86e-47 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PNEKKDIO_02453 6.41e-15 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDPglycerol
PNEKKDIO_02454 2.23e-62 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PNEKKDIO_02455 1.63e-68 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PNEKKDIO_02456 9.91e-155 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PNEKKDIO_02457 6.33e-178 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PNEKKDIO_02458 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PNEKKDIO_02459 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PNEKKDIO_02460 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
PNEKKDIO_02461 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
PNEKKDIO_02462 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PNEKKDIO_02463 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PNEKKDIO_02464 0.0 - - - - - - - -
PNEKKDIO_02465 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PNEKKDIO_02466 1.58e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PNEKKDIO_02467 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PNEKKDIO_02468 1.59e-248 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PNEKKDIO_02469 3.25e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
PNEKKDIO_02470 4.55e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_02471 2.11e-222 ywtF_2 - - K - - - Transcriptional regulator
PNEKKDIO_02472 6.95e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PNEKKDIO_02473 3.19e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PNEKKDIO_02474 2.29e-29 ywtC - - - - - - -
PNEKKDIO_02475 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PNEKKDIO_02476 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
PNEKKDIO_02477 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
PNEKKDIO_02478 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
PNEKKDIO_02479 2.52e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PNEKKDIO_02480 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PNEKKDIO_02481 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PNEKKDIO_02482 2.75e-202 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PNEKKDIO_02483 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
PNEKKDIO_02484 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
PNEKKDIO_02485 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
PNEKKDIO_02486 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
PNEKKDIO_02487 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PNEKKDIO_02488 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PNEKKDIO_02489 3.36e-218 alsR - - K - - - LysR substrate binding domain
PNEKKDIO_02490 3.52e-309 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PNEKKDIO_02491 4.33e-162 ywrJ - - - - - - -
PNEKKDIO_02492 3e-177 cotB - - - ko:K06325 - ko00000 -
PNEKKDIO_02493 5.33e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
PNEKKDIO_02495 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
PNEKKDIO_02496 6.19e-134 ykrK - - S - - - Domain of unknown function (DUF1836)
PNEKKDIO_02497 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PNEKKDIO_02498 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
PNEKKDIO_02500 1.14e-28 ykzE - - - - - - -
PNEKKDIO_02501 1.93e-243 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
PNEKKDIO_02502 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_02503 2.65e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PNEKKDIO_02505 1.55e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PNEKKDIO_02506 9.63e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PNEKKDIO_02507 8.12e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PNEKKDIO_02508 4.61e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PNEKKDIO_02509 5.62e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PNEKKDIO_02510 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PNEKKDIO_02511 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PNEKKDIO_02512 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PNEKKDIO_02513 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
PNEKKDIO_02515 5.84e-95 eag - - - - - - -
PNEKKDIO_02516 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PNEKKDIO_02517 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
PNEKKDIO_02518 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PNEKKDIO_02519 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PNEKKDIO_02520 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
PNEKKDIO_02521 6.76e-227 ykvI - - S - - - membrane
PNEKKDIO_02522 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PNEKKDIO_02523 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PNEKKDIO_02524 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PNEKKDIO_02525 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PNEKKDIO_02526 7.06e-80 - - - K - - - HxlR-like helix-turn-helix
PNEKKDIO_02527 1.55e-171 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_02528 3.51e-271 - - - M - - - Glycosyl transferases group 1
PNEKKDIO_02529 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
PNEKKDIO_02530 3.02e-205 - - - G - - - Glycosyl hydrolases family 18
PNEKKDIO_02531 5.35e-57 ykvR - - S - - - Protein of unknown function (DUF3219)
PNEKKDIO_02532 5.43e-35 ykvS - - S - - - protein conserved in bacteria
PNEKKDIO_02533 2.6e-39 - - - - - - - -
PNEKKDIO_02534 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
PNEKKDIO_02535 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_02536 5.57e-115 stoA - - CO - - - thiol-disulfide
PNEKKDIO_02537 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PNEKKDIO_02538 3.99e-09 - - - - - - - -
PNEKKDIO_02539 2.34e-265 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PNEKKDIO_02540 2.21e-228 ykvZ - - K - - - Transcriptional regulator
PNEKKDIO_02541 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
PNEKKDIO_02542 1.86e-82 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_02543 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_02544 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
PNEKKDIO_02545 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PNEKKDIO_02546 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_02547 1.01e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
PNEKKDIO_02548 1.86e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_02549 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_02550 2.33e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PNEKKDIO_02551 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
PNEKKDIO_02552 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PNEKKDIO_02553 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_02554 1.03e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PNEKKDIO_02555 1.05e-22 - - - - - - - -
PNEKKDIO_02556 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
PNEKKDIO_02557 3.71e-110 ykyB - - S - - - YkyB-like protein
PNEKKDIO_02558 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_02559 5.84e-115 ykuD - - S - - - protein conserved in bacteria
PNEKKDIO_02560 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
PNEKKDIO_02561 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_02562 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
PNEKKDIO_02563 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
PNEKKDIO_02564 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
PNEKKDIO_02565 7.83e-38 ykzF - - S - - - Antirepressor AbbA
PNEKKDIO_02566 5.15e-100 ykuL - - S - - - CBS domain
PNEKKDIO_02567 6.52e-216 ccpC - - K - - - Transcriptional regulator
PNEKKDIO_02568 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
PNEKKDIO_02569 5.2e-224 ykuO - - - - - - -
PNEKKDIO_02570 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
PNEKKDIO_02571 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PNEKKDIO_02572 3.23e-100 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PNEKKDIO_02573 6.79e-118 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PNEKKDIO_02574 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
PNEKKDIO_02575 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
PNEKKDIO_02576 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
PNEKKDIO_02577 1.47e-104 ykuV - - CO - - - thiol-disulfide
PNEKKDIO_02578 4.71e-122 rok - - K - - - Repressor of ComK
PNEKKDIO_02579 5.13e-38 yknT - - - ko:K06437 - ko00000 -
PNEKKDIO_02580 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
PNEKKDIO_02581 1.57e-118 - - - M - - - FR47-like protein
PNEKKDIO_02582 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
PNEKKDIO_02583 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
PNEKKDIO_02584 4.55e-22 yuaE - - S - - - DinB superfamily
PNEKKDIO_02585 1.13e-72 yuaE - - S - - - DinB superfamily
PNEKKDIO_02586 3.5e-138 yuaD - - - - - - -
PNEKKDIO_02587 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PNEKKDIO_02588 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PNEKKDIO_02589 5.02e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
PNEKKDIO_02590 5.83e-118 yuaB - - - - - - -
PNEKKDIO_02591 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PNEKKDIO_02592 6.18e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
PNEKKDIO_02593 3.31e-52 yubF - - S - - - yiaA/B two helix domain
PNEKKDIO_02594 5.35e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PNEKKDIO_02595 0.0 yubD - - P - - - Major Facilitator Superfamily
PNEKKDIO_02596 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
PNEKKDIO_02598 1.07e-66 - - - S - - - YolD-like protein
PNEKKDIO_02600 6.8e-92 - - - K - - - acetyltransferase
PNEKKDIO_02601 7.49e-33 - - - K - - - Helix-turn-helix domain
PNEKKDIO_02604 1.32e-136 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PNEKKDIO_02605 1.85e-40 xhlB - - S - - - SPP1 phage holin
PNEKKDIO_02606 1.56e-36 xhlA - - S - - - Haemolysin XhlA
PNEKKDIO_02611 2.58e-293 - - - S - - - peptidoglycan catabolic process
PNEKKDIO_02612 7.1e-10 - - - S - - - phage tail component
PNEKKDIO_02613 7.66e-203 - - - - - - - -
PNEKKDIO_02614 3.65e-37 - - - S - - - Phage tail assembly chaperone protein, TAC
PNEKKDIO_02615 2.7e-12 chiA - - G - - - Glycosyl hydrolases family 18
PNEKKDIO_02616 2.62e-43 - - - S - - - Phage tail tube protein
PNEKKDIO_02617 2.44e-39 - - - S - - - Protein of unknown function (DUF3168)
PNEKKDIO_02618 1.74e-47 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PNEKKDIO_02619 2.28e-37 - - - S - - - Phage head-tail joining protein
PNEKKDIO_02620 8.72e-38 - - - S - - - Phage gp6-like head-tail connector protein
PNEKKDIO_02622 4.89e-61 - - - S - - - viral capsid
PNEKKDIO_02623 3.09e-55 - - - S - - - Phage minor structural protein GP20
PNEKKDIO_02625 9.18e-117 - - - S - - - Phage Mu protein F like protein
PNEKKDIO_02626 1.89e-151 - - - S - - - Phage portal protein, SPP1 Gp6-like
PNEKKDIO_02628 6.17e-247 - - - S - - - Phage terminase large subunit
PNEKKDIO_02629 7.86e-59 - - - L ko:K07474 - ko00000 Terminase small subunit
PNEKKDIO_02631 7.5e-105 - - - L - - - Transposase
PNEKKDIO_02643 1.33e-130 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PNEKKDIO_02644 6.3e-162 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
PNEKKDIO_02649 1.3e-36 yqaO - - S - - - Phage-like element PBSX protein XtrA
PNEKKDIO_02651 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
PNEKKDIO_02654 5.07e-175 yqaM - - L - - - IstB-like ATP binding protein
PNEKKDIO_02655 9.69e-46 yqaL - - L - - - DnaD domain protein
PNEKKDIO_02656 8.87e-172 recT - - L ko:K07455 - ko00000,ko03400 RecT family
PNEKKDIO_02657 3.12e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
PNEKKDIO_02661 4.65e-112 - - - - - - - -
PNEKKDIO_02662 1.85e-85 - - - S - - - DNA binding
PNEKKDIO_02663 5.65e-22 - - - S - - - Helix-turn-helix domain
PNEKKDIO_02664 3.67e-23 - - - K - - - Helix-turn-helix domain
PNEKKDIO_02665 3.41e-22 - - - K - - - Helix-turn-helix XRE-family like proteins
PNEKKDIO_02667 1.31e-85 - - - - - - - -
PNEKKDIO_02668 2.12e-52 - - - S - - - Protein of unknown function (DUF4064)
PNEKKDIO_02669 5.6e-63 xkdA - - E - - - IrrE N-terminal-like domain
PNEKKDIO_02670 1.94e-32 int7 - - L - - - Belongs to the 'phage' integrase family
PNEKKDIO_02671 8.01e-165 int7 - - L - - - Belongs to the 'phage' integrase family
PNEKKDIO_02673 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PNEKKDIO_02674 2.45e-252 yubA - - S - - - transporter activity
PNEKKDIO_02675 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PNEKKDIO_02676 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
PNEKKDIO_02677 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
PNEKKDIO_02678 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PNEKKDIO_02679 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PNEKKDIO_02680 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
PNEKKDIO_02685 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
PNEKKDIO_02686 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
PNEKKDIO_02688 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
PNEKKDIO_02689 3.47e-141 xkdA - - E - - - IrrE N-terminal-like domain
PNEKKDIO_02690 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
PNEKKDIO_02691 6.96e-80 yjqB - - S - - - Pfam:DUF867
PNEKKDIO_02692 1.35e-80 yjqA - - S - - - Bacterial PH domain
PNEKKDIO_02693 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PNEKKDIO_02694 1.53e-40 - - - S - - - YCII-related domain
PNEKKDIO_02696 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PNEKKDIO_02697 7.1e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
PNEKKDIO_02698 6.25e-54 yjoA - - S - - - DinB family
PNEKKDIO_02699 8.8e-40 yjoA - - S - - - DinB family
PNEKKDIO_02700 2.64e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
PNEKKDIO_02701 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PNEKKDIO_02702 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
PNEKKDIO_02703 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
PNEKKDIO_02704 3.76e-287 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
PNEKKDIO_02705 3.69e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_02706 1.37e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
PNEKKDIO_02707 2.65e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
PNEKKDIO_02708 1.37e-246 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
PNEKKDIO_02709 6.16e-314 - - - G ko:K03292 - ko00000 symporter YjmB
PNEKKDIO_02710 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
PNEKKDIO_02711 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PNEKKDIO_02712 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
PNEKKDIO_02713 2.46e-118 yjlB - - S - - - Cupin domain
PNEKKDIO_02714 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
PNEKKDIO_02715 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PNEKKDIO_02716 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
PNEKKDIO_02717 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PNEKKDIO_02718 1.11e-41 - - - - - - - -
PNEKKDIO_02719 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PNEKKDIO_02720 2.74e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PNEKKDIO_02722 1.57e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PNEKKDIO_02725 1.31e-121 yjgD - - S - - - Protein of unknown function (DUF1641)
PNEKKDIO_02726 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PNEKKDIO_02727 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
PNEKKDIO_02728 3.95e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
PNEKKDIO_02729 2.98e-215 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PNEKKDIO_02730 4.62e-29 yjfB - - S - - - Putative motility protein
PNEKKDIO_02731 5.23e-107 - - - S - - - Protein of unknown function (DUF2690)
PNEKKDIO_02732 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PNEKKDIO_02734 1.52e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PNEKKDIO_02735 9.41e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
PNEKKDIO_02736 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
PNEKKDIO_02737 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PNEKKDIO_02739 1.08e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PNEKKDIO_02740 3e-50 yjdF3 - - S - - - Protein of unknown function (DUF2992)
PNEKKDIO_02741 1.4e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PNEKKDIO_02742 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_02743 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
PNEKKDIO_02744 0.000759 - - - - - - - -
PNEKKDIO_02745 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
PNEKKDIO_02746 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
PNEKKDIO_02747 2.71e-120 yqaS - - L - - - DNA packaging
PNEKKDIO_02748 1.01e-65 - - - S - - - YjcQ protein
PNEKKDIO_02749 3.13e-98 yjcP - - - - - - -
PNEKKDIO_02750 3.05e-104 - - - L - - - Transposase
PNEKKDIO_02753 1.52e-68 yjcN - - - - - - -
PNEKKDIO_02754 7.57e-269 - - - S - - - Putative amidase domain
PNEKKDIO_02758 3.32e-185 yjcL - - S - - - Protein of unknown function (DUF819)
PNEKKDIO_02759 7.63e-60 yjcL - - S - - - Protein of unknown function (DUF819)
PNEKKDIO_02760 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
PNEKKDIO_02761 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PNEKKDIO_02762 4.65e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PNEKKDIO_02763 7.77e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
PNEKKDIO_02764 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
PNEKKDIO_02765 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PNEKKDIO_02766 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNEKKDIO_02767 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PNEKKDIO_02768 9.1e-44 yaaB - - S - - - Domain of unknown function (DUF370)
PNEKKDIO_02769 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PNEKKDIO_02770 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
PNEKKDIO_02771 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PNEKKDIO_02772 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PNEKKDIO_02773 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PNEKKDIO_02774 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNEKKDIO_02775 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
PNEKKDIO_02776 9.06e-317 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PNEKKDIO_02777 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PNEKKDIO_02778 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PNEKKDIO_02779 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PNEKKDIO_02780 9.26e-98 - - - S - - - Bacterial PH domain
PNEKKDIO_02781 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
PNEKKDIO_02782 5.06e-151 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PNEKKDIO_02783 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
PNEKKDIO_02784 5.34e-227 yyaD - - S - - - Membrane
PNEKKDIO_02785 7.41e-45 yyzM - - S - - - protein conserved in bacteria
PNEKKDIO_02786 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PNEKKDIO_02787 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PNEKKDIO_02788 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PNEKKDIO_02789 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PNEKKDIO_02790 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PNEKKDIO_02791 9.44e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PNEKKDIO_02792 1.44e-228 ccpB - - K - - - Transcriptional regulator
PNEKKDIO_02793 1.99e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_02794 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
PNEKKDIO_02795 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
PNEKKDIO_02796 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
PNEKKDIO_02797 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PNEKKDIO_02798 5.69e-207 - - - EG - - - EamA-like transporter family
PNEKKDIO_02799 5.45e-88 - - - K - - - MerR HTH family regulatory protein
PNEKKDIO_02800 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
PNEKKDIO_02801 1.34e-312 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_02802 1.67e-134 yyaP - - H - - - RibD C-terminal domain
PNEKKDIO_02803 3.02e-85 - - - S - - - YjbR
PNEKKDIO_02804 6.67e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PNEKKDIO_02805 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
PNEKKDIO_02806 8.44e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
PNEKKDIO_02807 4.54e-100 yybA - - K - - - transcriptional
PNEKKDIO_02808 2.07e-162 - - - S - - - Metallo-beta-lactamase superfamily
PNEKKDIO_02809 5.55e-94 yybC - - - - - - -
PNEKKDIO_02810 1.31e-102 yjcF - - S - - - Acetyltransferase (GNAT) domain
PNEKKDIO_02811 1.31e-210 yybE - - K - - - Transcriptional regulator
PNEKKDIO_02812 5.24e-278 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_02813 8.05e-162 yybG - - S - - - Pentapeptide repeat-containing protein
PNEKKDIO_02814 1.23e-87 - - - S - - - SnoaL-like domain
PNEKKDIO_02815 2.13e-185 - - - - - - - -
PNEKKDIO_02816 1.77e-123 - - - K - - - TipAS antibiotic-recognition domain
PNEKKDIO_02817 4.1e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_02819 2.73e-91 - - - - - - - -
PNEKKDIO_02820 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
PNEKKDIO_02821 3.87e-89 yybR - - K - - - Transcriptional regulator
PNEKKDIO_02822 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
PNEKKDIO_02824 5.23e-205 yybS - - S - - - membrane
PNEKKDIO_02825 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PNEKKDIO_02826 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PNEKKDIO_02827 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PNEKKDIO_02828 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
PNEKKDIO_02829 1.89e-22 yycC - - K - - - YycC-like protein
PNEKKDIO_02831 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PNEKKDIO_02832 9.13e-08 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PNEKKDIO_02833 8.67e-286 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PNEKKDIO_02834 1.7e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_02835 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PNEKKDIO_02838 4.08e-112 yteJ - - S - - - RDD family
PNEKKDIO_02839 3.96e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PNEKKDIO_02840 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PNEKKDIO_02841 0.0 ytcJ - - S - - - amidohydrolase
PNEKKDIO_02842 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PNEKKDIO_02843 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PNEKKDIO_02844 3.62e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PNEKKDIO_02845 3.2e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PNEKKDIO_02846 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PNEKKDIO_02847 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PNEKKDIO_02848 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PNEKKDIO_02849 2.94e-142 yttP - - K - - - Transcriptional regulator
PNEKKDIO_02850 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PNEKKDIO_02851 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
PNEKKDIO_02852 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PNEKKDIO_02854 9.27e-95 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PNEKKDIO_02855 1.43e-146 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PNEKKDIO_02856 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PNEKKDIO_02857 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PNEKKDIO_02858 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PNEKKDIO_02859 3.82e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
PNEKKDIO_02860 4.58e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PNEKKDIO_02861 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PNEKKDIO_02862 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PNEKKDIO_02863 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PNEKKDIO_02864 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
PNEKKDIO_02865 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
PNEKKDIO_02866 1e-61 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PNEKKDIO_02867 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PNEKKDIO_02868 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PNEKKDIO_02869 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PNEKKDIO_02870 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
PNEKKDIO_02871 3.17e-75 ytpP - - CO - - - Thioredoxin
PNEKKDIO_02872 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PNEKKDIO_02873 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PNEKKDIO_02874 4.06e-68 ytzB - - S - - - small secreted protein
PNEKKDIO_02875 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PNEKKDIO_02876 2.52e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PNEKKDIO_02877 3.07e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PNEKKDIO_02878 9.51e-61 ytzH - - S - - - YtzH-like protein
PNEKKDIO_02879 3.02e-192 ytmP - - M - - - Phosphotransferase
PNEKKDIO_02880 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PNEKKDIO_02881 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PNEKKDIO_02882 4.92e-212 ytlQ - - - - - - -
PNEKKDIO_02883 1.56e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PNEKKDIO_02884 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PNEKKDIO_02885 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
PNEKKDIO_02886 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
PNEKKDIO_02887 5.82e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PNEKKDIO_02888 3.27e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PNEKKDIO_02889 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
PNEKKDIO_02890 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PNEKKDIO_02891 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_02892 2e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
PNEKKDIO_02893 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PNEKKDIO_02894 2.14e-36 yteV - - S - - - Sporulation protein Cse60
PNEKKDIO_02895 3.81e-150 yteU - - S - - - Integral membrane protein
PNEKKDIO_02896 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
PNEKKDIO_02897 6.15e-34 yteS - - G - - - transport
PNEKKDIO_02898 1.31e-48 yteS - - G - - - transport
PNEKKDIO_02899 2.39e-171 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
PNEKKDIO_02900 4.35e-192 yqfA - - S - - - UPF0365 protein
PNEKKDIO_02901 7.62e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
PNEKKDIO_02902 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
PNEKKDIO_02903 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PNEKKDIO_02904 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PNEKKDIO_02905 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
PNEKKDIO_02906 1.68e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PNEKKDIO_02907 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
PNEKKDIO_02908 6.58e-255 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PNEKKDIO_02909 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PNEKKDIO_02910 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PNEKKDIO_02911 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PNEKKDIO_02912 1.23e-277 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PNEKKDIO_02913 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PNEKKDIO_02914 2.37e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
PNEKKDIO_02915 3.42e-46 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PNEKKDIO_02916 1.23e-195 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PNEKKDIO_02917 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PNEKKDIO_02918 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PNEKKDIO_02919 2.36e-22 - - - S - - - YqzM-like protein
PNEKKDIO_02920 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PNEKKDIO_02921 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PNEKKDIO_02922 4.49e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PNEKKDIO_02923 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNEKKDIO_02924 9.8e-179 yqeM - - Q - - - Methyltransferase
PNEKKDIO_02925 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PNEKKDIO_02926 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PNEKKDIO_02927 4.99e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PNEKKDIO_02928 1.27e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
PNEKKDIO_02929 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PNEKKDIO_02930 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PNEKKDIO_02931 8.31e-78 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PNEKKDIO_02933 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
PNEKKDIO_02934 9.35e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PNEKKDIO_02935 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
PNEKKDIO_02936 2.19e-216 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
PNEKKDIO_02937 9.38e-171 - - - - - - - -
PNEKKDIO_02938 5.1e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
PNEKKDIO_02939 9.25e-73 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_02940 2.91e-81 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_02941 1.78e-282 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
PNEKKDIO_02942 0.0 - - - L ko:K06400 - ko00000 Recombinase
PNEKKDIO_02943 1.15e-241 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PNEKKDIO_02946 1.14e-117 - - - S - - - Tetratricopeptide repeat
PNEKKDIO_02949 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PNEKKDIO_02950 1.2e-106 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PNEKKDIO_02951 1.12e-158 - - - EGP - - - Necrosis inducing protein (NPP1)
PNEKKDIO_02952 9.53e-134 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PNEKKDIO_02953 6.69e-33 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
PNEKKDIO_02954 1.1e-78 yqaS - - L - - - DNA packaging
PNEKKDIO_02955 8.63e-32 - - - - - - - -
PNEKKDIO_02956 0.000188 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PNEKKDIO_02957 2.54e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
PNEKKDIO_02958 4.7e-98 yqaQ - - L - - - Transposase
PNEKKDIO_02960 1.44e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
PNEKKDIO_02961 2.57e-53 rusA - - L - - - Endodeoxyribonuclease RusA
PNEKKDIO_02964 4.36e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
PNEKKDIO_02965 3.88e-119 - - - K - - - Transcriptional regulator PadR-like family
PNEKKDIO_02966 3.84e-126 yqaC - - F - - - adenylate kinase activity
PNEKKDIO_02967 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_02968 1.94e-145 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
PNEKKDIO_02969 2.23e-274 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
PNEKKDIO_02970 3.1e-208 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PNEKKDIO_02971 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_02972 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PNEKKDIO_02973 5.07e-201 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PNEKKDIO_02974 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_02975 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
PNEKKDIO_02976 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
PNEKKDIO_02977 2.74e-243 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
PNEKKDIO_02978 2.17e-133 ytqB - - J - - - Putative rRNA methylase
PNEKKDIO_02979 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
PNEKKDIO_02980 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
PNEKKDIO_02981 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PNEKKDIO_02982 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PNEKKDIO_02983 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PNEKKDIO_02984 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PNEKKDIO_02985 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PNEKKDIO_02986 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
PNEKKDIO_02987 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PNEKKDIO_02988 3.78e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PNEKKDIO_02989 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PNEKKDIO_02990 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PNEKKDIO_02991 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PNEKKDIO_02992 1.59e-81 ytkC - - S - - - Bacteriophage holin family
PNEKKDIO_02993 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PNEKKDIO_02995 3.93e-94 ytkA - - S - - - YtkA-like
PNEKKDIO_02996 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PNEKKDIO_02997 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PNEKKDIO_02998 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PNEKKDIO_02999 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PNEKKDIO_03000 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PNEKKDIO_03001 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
PNEKKDIO_03002 2.27e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
PNEKKDIO_03003 5.48e-298 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PNEKKDIO_03004 6.86e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PNEKKDIO_03005 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PNEKKDIO_03006 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PNEKKDIO_03007 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PNEKKDIO_03008 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PNEKKDIO_03009 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PNEKKDIO_03010 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PNEKKDIO_03011 1.09e-294 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PNEKKDIO_03012 1.01e-29 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PNEKKDIO_03013 1.75e-168 yteA - - T - - - COG1734 DnaK suppressor protein
PNEKKDIO_03014 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
PNEKKDIO_03015 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PNEKKDIO_03016 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
PNEKKDIO_03017 4.83e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
PNEKKDIO_03019 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
PNEKKDIO_03020 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
PNEKKDIO_03021 1.4e-07 cotI - - S ko:K06331 - ko00000 Spore coat protein
PNEKKDIO_03022 7.38e-238 cotI - - S ko:K06331 - ko00000 Spore coat protein
PNEKKDIO_03023 1.1e-98 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
PNEKKDIO_03024 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PNEKKDIO_03025 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
PNEKKDIO_03026 4.52e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
PNEKKDIO_03027 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PNEKKDIO_03028 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PNEKKDIO_03050 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PNEKKDIO_03051 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
PNEKKDIO_03052 1.36e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
PNEKKDIO_03053 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PNEKKDIO_03054 3.86e-213 yocS - - S ko:K03453 - ko00000 -transporter
PNEKKDIO_03055 5.23e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PNEKKDIO_03056 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PNEKKDIO_03057 0.0 yojO - - P - - - Von Willebrand factor
PNEKKDIO_03058 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
PNEKKDIO_03059 8.54e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PNEKKDIO_03060 6.16e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PNEKKDIO_03061 6.56e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
PNEKKDIO_03062 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PNEKKDIO_03064 8.88e-121 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PNEKKDIO_03065 1.97e-150 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PNEKKDIO_03066 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PNEKKDIO_03067 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
PNEKKDIO_03068 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
PNEKKDIO_03069 1.85e-58 - - - - - - - -
PNEKKDIO_03070 4.37e-128 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
PNEKKDIO_03071 3.03e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
PNEKKDIO_03072 5.59e-14 - - - - - - - -
PNEKKDIO_03073 1.86e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PNEKKDIO_03074 5.64e-84 iolK - - S - - - tautomerase
PNEKKDIO_03075 2.63e-73 yodB - - K - - - transcriptional
PNEKKDIO_03076 1.11e-139 yodC - - C - - - nitroreductase
PNEKKDIO_03077 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
PNEKKDIO_03078 6.83e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PNEKKDIO_03079 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
PNEKKDIO_03080 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNEKKDIO_03081 5.17e-315 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PNEKKDIO_03082 7.45e-167 yodH - - Q - - - Methyltransferase
PNEKKDIO_03083 2.93e-42 yodI - - - - - - -
PNEKKDIO_03084 1.25e-148 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PNEKKDIO_03085 1.02e-20 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PNEKKDIO_03086 7.36e-114 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PNEKKDIO_03087 2.27e-32 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PNEKKDIO_03088 2.08e-12 - - - - - - - -
PNEKKDIO_03089 1.17e-71 yodL - - S - - - YodL-like
PNEKKDIO_03090 6.67e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PNEKKDIO_03091 5.18e-34 yozD - - S - - - YozD-like protein
PNEKKDIO_03093 1.29e-159 yodN - - - - - - -
PNEKKDIO_03094 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
PNEKKDIO_03095 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
PNEKKDIO_03096 3.09e-66 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PNEKKDIO_03097 7.48e-37 - - - - - - - -
PNEKKDIO_03099 1.18e-117 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PNEKKDIO_03102 1.07e-38 - - - S - - - Macro domain
PNEKKDIO_03111 1.59e-207 - - - S - - - Calcineurin-like phosphoesterase
PNEKKDIO_03112 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PNEKKDIO_03115 1.92e-48 - - - - - - - -
PNEKKDIO_03117 4.67e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PNEKKDIO_03118 2.53e-206 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PNEKKDIO_03121 7.54e-22 - - - - - - - -
PNEKKDIO_03122 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PNEKKDIO_03123 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
PNEKKDIO_03124 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PNEKKDIO_03125 7.01e-155 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PNEKKDIO_03126 4.08e-44 - - - - - - - -
PNEKKDIO_03127 8.75e-91 - - - - - - - -
PNEKKDIO_03128 3.05e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
PNEKKDIO_03129 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PNEKKDIO_03130 5.61e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PNEKKDIO_03131 4.49e-144 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PNEKKDIO_03132 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PNEKKDIO_03133 3.35e-288 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PNEKKDIO_03134 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PNEKKDIO_03135 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PNEKKDIO_03136 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
PNEKKDIO_03137 6.36e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
PNEKKDIO_03138 2.07e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PNEKKDIO_03139 3.71e-154 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PNEKKDIO_03140 8.75e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
PNEKKDIO_03141 1.84e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PNEKKDIO_03142 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PNEKKDIO_03143 3.99e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PNEKKDIO_03144 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PNEKKDIO_03145 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
PNEKKDIO_03146 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
PNEKKDIO_03147 3.54e-65 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_03148 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PNEKKDIO_03149 7.15e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
PNEKKDIO_03150 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PNEKKDIO_03151 7.05e-271 yvmA - - EGP - - - Major Facilitator Superfamily
PNEKKDIO_03152 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
PNEKKDIO_03153 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PNEKKDIO_03154 1.66e-220 yvlB - - S - - - Putative adhesin
PNEKKDIO_03155 8.09e-65 yvlA - - - - - - -
PNEKKDIO_03156 2.73e-46 yvkN - - - - - - -
PNEKKDIO_03157 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PNEKKDIO_03158 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PNEKKDIO_03159 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PNEKKDIO_03160 2.54e-42 csbA - - S - - - protein conserved in bacteria
PNEKKDIO_03161 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
PNEKKDIO_03162 1.43e-131 yvkB - - K - - - Transcriptional regulator
PNEKKDIO_03163 3.03e-295 yvkA - - P - - - -transporter
PNEKKDIO_03164 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PNEKKDIO_03165 1.38e-73 swrA - - S - - - Swarming motility protein
PNEKKDIO_03166 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PNEKKDIO_03167 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PNEKKDIO_03168 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PNEKKDIO_03169 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PNEKKDIO_03170 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PNEKKDIO_03171 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PNEKKDIO_03172 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PNEKKDIO_03173 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PNEKKDIO_03174 9.14e-88 - - - - - - - -
PNEKKDIO_03175 1.56e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
PNEKKDIO_03176 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
PNEKKDIO_03177 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PNEKKDIO_03178 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
PNEKKDIO_03179 2.91e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PNEKKDIO_03180 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PNEKKDIO_03181 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PNEKKDIO_03182 1.81e-41 yazB - - K - - - transcriptional
PNEKKDIO_03183 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PNEKKDIO_03184 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PNEKKDIO_03185 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PNEKKDIO_03186 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
PNEKKDIO_03187 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
PNEKKDIO_03188 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PNEKKDIO_03189 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PNEKKDIO_03190 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
PNEKKDIO_03191 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PNEKKDIO_03192 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PNEKKDIO_03193 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PNEKKDIO_03194 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PNEKKDIO_03195 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PNEKKDIO_03196 9.83e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
PNEKKDIO_03197 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PNEKKDIO_03198 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
PNEKKDIO_03201 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PNEKKDIO_03202 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PNEKKDIO_03203 4.28e-137 yabQ - - S - - - spore cortex biosynthesis protein
PNEKKDIO_03204 1.91e-66 yabP - - S - - - Sporulation protein YabP
PNEKKDIO_03205 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PNEKKDIO_03206 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PNEKKDIO_03207 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PNEKKDIO_03208 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
PNEKKDIO_03209 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PNEKKDIO_03210 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
PNEKKDIO_03211 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PNEKKDIO_03212 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PNEKKDIO_03213 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PNEKKDIO_03214 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PNEKKDIO_03215 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PNEKKDIO_03216 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
PNEKKDIO_03217 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PNEKKDIO_03218 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PNEKKDIO_03219 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
PNEKKDIO_03220 5.32e-53 veg - - S - - - protein conserved in bacteria
PNEKKDIO_03221 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
PNEKKDIO_03222 2.91e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PNEKKDIO_03223 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PNEKKDIO_03224 4.1e-278 yabE - - T - - - protein conserved in bacteria
PNEKKDIO_03225 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
PNEKKDIO_03226 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PNEKKDIO_03227 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
PNEKKDIO_03228 1.2e-206 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PNEKKDIO_03229 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PNEKKDIO_03230 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
PNEKKDIO_03231 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
PNEKKDIO_03232 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
PNEKKDIO_03233 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PNEKKDIO_03234 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
PNEKKDIO_03235 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
PNEKKDIO_03238 6.11e-54 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEKKDIO_03239 2.66e-16 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEKKDIO_03240 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEKKDIO_03241 8.93e-192 ypuA - - S - - - Secreted protein
PNEKKDIO_03242 1.14e-120 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PNEKKDIO_03243 4.04e-191 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PNEKKDIO_03244 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
PNEKKDIO_03245 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
PNEKKDIO_03246 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
PNEKKDIO_03247 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PNEKKDIO_03248 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PNEKKDIO_03249 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
PNEKKDIO_03250 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
PNEKKDIO_03251 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_03252 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PNEKKDIO_03253 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
PNEKKDIO_03254 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PNEKKDIO_03255 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PNEKKDIO_03256 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PNEKKDIO_03257 1.12e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
PNEKKDIO_03258 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
PNEKKDIO_03259 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PNEKKDIO_03260 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PNEKKDIO_03261 3.08e-43 yqkK - - - - - - -
PNEKKDIO_03262 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PNEKKDIO_03263 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PNEKKDIO_03264 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
PNEKKDIO_03265 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
PNEKKDIO_03266 3.18e-77 ansR - - K - - - Transcriptional regulator
PNEKKDIO_03267 6.16e-282 yqxK - - L - - - DNA helicase
PNEKKDIO_03268 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PNEKKDIO_03269 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
PNEKKDIO_03270 1.26e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PNEKKDIO_03271 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
PNEKKDIO_03272 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PNEKKDIO_03273 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
PNEKKDIO_03274 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
PNEKKDIO_03275 3.37e-250 yqkA - - K - - - GrpB protein
PNEKKDIO_03276 5.3e-70 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
PNEKKDIO_03277 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
PNEKKDIO_03278 6.53e-66 yqiX - - S - - - YolD-like protein
PNEKKDIO_03279 1.71e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_03281 2.42e-242 yqjV - - G - - - Major Facilitator Superfamily
PNEKKDIO_03283 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PNEKKDIO_03284 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PNEKKDIO_03285 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PNEKKDIO_03286 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_03287 1.09e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PNEKKDIO_03288 9.98e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PNEKKDIO_03289 0.0 rocB - - E - - - arginine degradation protein
PNEKKDIO_03290 5.78e-191 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PNEKKDIO_03291 1.45e-29 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PNEKKDIO_03292 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PNEKKDIO_03293 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PNEKKDIO_03294 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PNEKKDIO_03295 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PNEKKDIO_03296 2.41e-288 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PNEKKDIO_03297 2.64e-125 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
PNEKKDIO_03298 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PNEKKDIO_03299 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
PNEKKDIO_03300 8.14e-73 yusE - - CO - - - Thioredoxin
PNEKKDIO_03301 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
PNEKKDIO_03302 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
PNEKKDIO_03303 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PNEKKDIO_03304 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PNEKKDIO_03305 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PNEKKDIO_03306 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
PNEKKDIO_03307 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
PNEKKDIO_03308 2.86e-14 - - - S - - - YuzL-like protein
PNEKKDIO_03309 1.21e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PNEKKDIO_03310 2.23e-54 - - - - - - - -
PNEKKDIO_03311 8.66e-70 yusN - - M - - - Coat F domain
PNEKKDIO_03312 4.29e-96 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
PNEKKDIO_03313 0.0 yusP - - P - - - Major facilitator superfamily
PNEKKDIO_03314 1.7e-84 yusQ - - S - - - Tautomerase enzyme
PNEKKDIO_03315 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_03316 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
PNEKKDIO_03317 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
PNEKKDIO_03318 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PNEKKDIO_03319 3.48e-88 - - - S - - - YusW-like protein
PNEKKDIO_03320 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
PNEKKDIO_03321 1.5e-194 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_03322 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
PNEKKDIO_03323 9.21e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PNEKKDIO_03324 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_03325 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_03326 3.06e-204 yuxN - - K - - - Transcriptional regulator
PNEKKDIO_03327 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PNEKKDIO_03328 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
PNEKKDIO_03329 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PNEKKDIO_03330 9.69e-252 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PNEKKDIO_03331 6.86e-240 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
PNEKKDIO_03332 2.69e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_03333 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_03334 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
PNEKKDIO_03335 3.11e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PNEKKDIO_03336 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PNEKKDIO_03337 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
PNEKKDIO_03338 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_03339 3.34e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
PNEKKDIO_03340 7.39e-309 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PNEKKDIO_03341 1.23e-232 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_03342 3.14e-62 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PNEKKDIO_03343 3.74e-109 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PNEKKDIO_03344 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PNEKKDIO_03345 2.51e-105 yqxM - - - ko:K19433 - ko00000 -
PNEKKDIO_03346 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
PNEKKDIO_03347 2.84e-36 yqzE - - S - - - YqzE-like protein
PNEKKDIO_03348 2.66e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
PNEKKDIO_03349 2.47e-61 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PNEKKDIO_03350 1.41e-75 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
PNEKKDIO_03351 3.21e-72 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
PNEKKDIO_03352 4.39e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PNEKKDIO_03353 1.76e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
PNEKKDIO_03354 2.59e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PNEKKDIO_03356 1.22e-05 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
PNEKKDIO_03357 1.51e-233 yqxL - - P - - - Mg2 transporter protein
PNEKKDIO_03358 4.06e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PNEKKDIO_03359 6.84e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PNEKKDIO_03361 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PNEKKDIO_03362 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
PNEKKDIO_03363 6.2e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PNEKKDIO_03364 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
PNEKKDIO_03365 7.34e-66 yqgV - - S - - - Thiamine-binding protein
PNEKKDIO_03366 5.65e-258 yqgU - - - - - - -
PNEKKDIO_03367 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
PNEKKDIO_03368 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PNEKKDIO_03369 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PNEKKDIO_03370 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
PNEKKDIO_03371 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
PNEKKDIO_03372 3.38e-14 yqgO - - - - - - -
PNEKKDIO_03373 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PNEKKDIO_03374 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PNEKKDIO_03375 1.49e-252 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
PNEKKDIO_03377 3.42e-68 yqzD - - - - - - -
PNEKKDIO_03378 1.09e-93 yqzC - - S - - - YceG-like family
PNEKKDIO_03379 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNEKKDIO_03380 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PNEKKDIO_03381 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PNEKKDIO_03382 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PNEKKDIO_03383 2.27e-195 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PNEKKDIO_03384 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PNEKKDIO_03385 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
PNEKKDIO_03386 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PNEKKDIO_03387 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
PNEKKDIO_03388 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
PNEKKDIO_03389 1.16e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
PNEKKDIO_03390 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PNEKKDIO_03391 8.3e-81 yqfX - - S - - - membrane
PNEKKDIO_03392 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
PNEKKDIO_03393 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
PNEKKDIO_03394 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PNEKKDIO_03395 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
PNEKKDIO_03396 5.57e-204 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PNEKKDIO_03397 1.59e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
PNEKKDIO_03398 7.99e-41 ypeQ - - S - - - Zinc-finger
PNEKKDIO_03399 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
PNEKKDIO_03400 1.17e-22 degR - - - - - - -
PNEKKDIO_03401 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PNEKKDIO_03402 5.22e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PNEKKDIO_03404 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PNEKKDIO_03405 1.49e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PNEKKDIO_03406 6.65e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
PNEKKDIO_03407 9.9e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
PNEKKDIO_03408 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PNEKKDIO_03409 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
PNEKKDIO_03410 6.89e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
PNEKKDIO_03411 1.16e-146 ypjP - - S - - - YpjP-like protein
PNEKKDIO_03412 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PNEKKDIO_03413 9.52e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PNEKKDIO_03414 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PNEKKDIO_03415 1.91e-142 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PNEKKDIO_03416 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PNEKKDIO_03417 8.1e-236 yplP - - K - - - Transcriptional regulator
PNEKKDIO_03418 1.16e-243 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PNEKKDIO_03419 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
PNEKKDIO_03420 7.93e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PNEKKDIO_03421 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
PNEKKDIO_03422 1.22e-64 ypmS - - S - - - protein conserved in bacteria
PNEKKDIO_03423 2.13e-40 ypmT - - S - - - Uncharacterized ympT
PNEKKDIO_03424 1.75e-228 mepA - - V - - - MATE efflux family protein
PNEKKDIO_03425 4.14e-94 ypoP - - K - - - transcriptional
PNEKKDIO_03426 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PNEKKDIO_03427 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PNEKKDIO_03428 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PNEKKDIO_03429 1.39e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
PNEKKDIO_03430 2.33e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
PNEKKDIO_03431 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
PNEKKDIO_03432 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
PNEKKDIO_03433 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
PNEKKDIO_03434 3.98e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
PNEKKDIO_03436 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PNEKKDIO_03437 3.41e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PNEKKDIO_03438 9.06e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PNEKKDIO_03439 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
PNEKKDIO_03440 5.27e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
PNEKKDIO_03441 9.56e-252 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PNEKKDIO_03442 1.76e-119 - - - S - - - Recombinase
PNEKKDIO_03443 1.55e-227 - - - S - - - Recombinase
PNEKKDIO_03445 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PNEKKDIO_03446 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PNEKKDIO_03447 0.0 yueB - - S - - - type VII secretion protein EsaA
PNEKKDIO_03448 1.22e-60 yueC - - S - - - Family of unknown function (DUF5383)
PNEKKDIO_03449 4.12e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_03450 7.78e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
PNEKKDIO_03451 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
PNEKKDIO_03452 2.17e-14 - - - S - - - Protein of unknown function (DUF2283)
PNEKKDIO_03453 1.35e-244 yueF - - S - - - transporter activity
PNEKKDIO_03454 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
PNEKKDIO_03455 1.63e-52 yueH - - S - - - YueH-like protein
PNEKKDIO_03456 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
PNEKKDIO_03457 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
PNEKKDIO_03458 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PNEKKDIO_03459 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
PNEKKDIO_03460 8.73e-09 yuzC - - - - - - -
PNEKKDIO_03461 6.29e-10 - - - S - - - DegQ (SacQ) family
PNEKKDIO_03462 7.24e-179 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
PNEKKDIO_03464 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_03465 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PNEKKDIO_03466 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
PNEKKDIO_03467 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
PNEKKDIO_03468 5.62e-21 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PNEKKDIO_03469 2.47e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PNEKKDIO_03470 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PNEKKDIO_03471 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PNEKKDIO_03472 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PNEKKDIO_03473 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PNEKKDIO_03474 1.42e-21 - - - - - - - -
PNEKKDIO_03475 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
PNEKKDIO_03476 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PNEKKDIO_03477 6.39e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PNEKKDIO_03478 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_03479 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
PNEKKDIO_03480 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PNEKKDIO_03481 2.62e-185 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PNEKKDIO_03482 7.84e-213 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEKKDIO_03483 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEKKDIO_03484 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
PNEKKDIO_03485 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PNEKKDIO_03486 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PNEKKDIO_03487 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PNEKKDIO_03488 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PNEKKDIO_03489 3.16e-231 ybaC - - S - - - Alpha/beta hydrolase family
PNEKKDIO_03490 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PNEKKDIO_03491 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PNEKKDIO_03492 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PNEKKDIO_03493 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PNEKKDIO_03494 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PNEKKDIO_03495 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PNEKKDIO_03496 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PNEKKDIO_03497 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PNEKKDIO_03498 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PNEKKDIO_03499 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PNEKKDIO_03500 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PNEKKDIO_03501 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PNEKKDIO_03502 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PNEKKDIO_03503 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PNEKKDIO_03504 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PNEKKDIO_03505 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PNEKKDIO_03506 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PNEKKDIO_03507 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PNEKKDIO_03508 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PNEKKDIO_03509 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PNEKKDIO_03510 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PNEKKDIO_03511 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PNEKKDIO_03512 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PNEKKDIO_03513 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PNEKKDIO_03514 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PNEKKDIO_03515 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PNEKKDIO_03516 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PNEKKDIO_03517 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PNEKKDIO_03518 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PNEKKDIO_03519 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PNEKKDIO_03520 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEKKDIO_03521 2.13e-192 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEKKDIO_03522 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PNEKKDIO_03523 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PNEKKDIO_03524 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PNEKKDIO_03525 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PNEKKDIO_03526 3.56e-185 ybaJ - - Q - - - Methyltransferase domain
PNEKKDIO_03527 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
PNEKKDIO_03528 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PNEKKDIO_03529 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PNEKKDIO_03530 2.84e-39 gerD - - - ko:K06294 - ko00000 -
PNEKKDIO_03531 1.37e-28 gerD - - - ko:K06294 - ko00000 -
PNEKKDIO_03532 2.41e-20 gerD - - - ko:K06294 - ko00000 -
PNEKKDIO_03533 1.01e-149 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PNEKKDIO_03534 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
PNEKKDIO_03535 0.00015 - - - - ko:K06429 - ko00000 -
PNEKKDIO_03536 2.26e-213 ypcP - - L - - - 5'3' exonuclease
PNEKKDIO_03537 1.08e-11 - - - - - - - -
PNEKKDIO_03538 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
PNEKKDIO_03539 7.69e-25 ypbR - - S - - - Dynamin family
PNEKKDIO_03540 0.0 ypbR - - S - - - Dynamin family
PNEKKDIO_03541 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
PNEKKDIO_03542 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PNEKKDIO_03543 2.12e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PNEKKDIO_03544 1.35e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PNEKKDIO_03545 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PNEKKDIO_03546 4.52e-29 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PNEKKDIO_03547 1.43e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
PNEKKDIO_03548 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
PNEKKDIO_03549 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
PNEKKDIO_03550 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
PNEKKDIO_03551 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PNEKKDIO_03552 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PNEKKDIO_03553 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
PNEKKDIO_03555 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PNEKKDIO_03556 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PNEKKDIO_03557 3.15e-133 ypsA - - S - - - Belongs to the UPF0398 family
PNEKKDIO_03558 2.07e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
PNEKKDIO_03559 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PNEKKDIO_03560 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
PNEKKDIO_03561 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PNEKKDIO_03562 8.72e-68 yppG - - S - - - YppG-like protein
PNEKKDIO_03563 9.21e-11 - - - S - - - YppF-like protein
PNEKKDIO_03564 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
PNEKKDIO_03566 1.03e-237 yppC - - S - - - Protein of unknown function (DUF2515)
PNEKKDIO_03567 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PNEKKDIO_03568 2.79e-41 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PNEKKDIO_03569 4.9e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PNEKKDIO_03570 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PNEKKDIO_03571 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PNEKKDIO_03572 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PNEKKDIO_03573 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
PNEKKDIO_03574 8.02e-152 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PNEKKDIO_03576 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PNEKKDIO_03577 2.26e-37 - - - - - - - -
PNEKKDIO_03578 3.28e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
PNEKKDIO_03579 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PNEKKDIO_03580 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PNEKKDIO_03581 1.7e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
PNEKKDIO_03582 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PNEKKDIO_03583 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PNEKKDIO_03584 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
PNEKKDIO_03585 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PNEKKDIO_03586 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
PNEKKDIO_03587 0.0 bkdR - - KT - - - Transcriptional regulator
PNEKKDIO_03588 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
PNEKKDIO_03589 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PNEKKDIO_03590 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
PNEKKDIO_03591 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PNEKKDIO_03592 1.58e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PNEKKDIO_03593 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PNEKKDIO_03594 8.49e-285 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PNEKKDIO_03595 1.06e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
PNEKKDIO_03596 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_03597 3.47e-115 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PNEKKDIO_03598 9.55e-80 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PNEKKDIO_03599 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
PNEKKDIO_03601 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_03602 2.64e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_03603 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PNEKKDIO_03604 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PNEKKDIO_03605 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
PNEKKDIO_03606 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PNEKKDIO_03607 2.07e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PNEKKDIO_03608 5.6e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
PNEKKDIO_03609 2.24e-50 - - - - - - - -
PNEKKDIO_03610 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
PNEKKDIO_03611 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
PNEKKDIO_03612 1.72e-94 yugN - - S - - - YugN-like family
PNEKKDIO_03614 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PNEKKDIO_03615 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
PNEKKDIO_03616 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
PNEKKDIO_03617 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
PNEKKDIO_03618 8.01e-52 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PNEKKDIO_03619 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
PNEKKDIO_03620 6.74e-112 alaR - - K - - - Transcriptional regulator
PNEKKDIO_03621 9.89e-201 yugF - - I - - - Hydrolase
PNEKKDIO_03622 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
PNEKKDIO_03623 1.11e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PNEKKDIO_03624 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_03625 4.84e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
PNEKKDIO_03626 3.46e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
PNEKKDIO_03628 2.97e-240 yuxJ - - EGP - - - Major facilitator superfamily
PNEKKDIO_03629 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
PNEKKDIO_03630 1.92e-97 yuxK - - S - - - protein conserved in bacteria
PNEKKDIO_03631 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
PNEKKDIO_03632 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PNEKKDIO_03633 1.99e-195 ytdP - - K - - - Transcriptional regulator
PNEKKDIO_03634 1.64e-303 ytdP - - K - - - Transcriptional regulator
PNEKKDIO_03635 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PNEKKDIO_03636 1.39e-182 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PNEKKDIO_03637 1.82e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
PNEKKDIO_03638 1.4e-282 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PNEKKDIO_03639 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PNEKKDIO_03640 1.62e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PNEKKDIO_03641 1.05e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PNEKKDIO_03642 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PNEKKDIO_03643 1.92e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PNEKKDIO_03644 2.77e-220 - - - S - - - Acetyl xylan esterase (AXE1)
PNEKKDIO_03645 2.64e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_03646 3.22e-306 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PNEKKDIO_03647 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PNEKKDIO_03648 8.93e-185 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PNEKKDIO_03649 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PNEKKDIO_03650 1.22e-68 ytwF - - P - - - Sulfurtransferase
PNEKKDIO_03651 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PNEKKDIO_03652 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
PNEKKDIO_03653 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PNEKKDIO_03654 1.41e-267 yttB - - EGP - - - Major facilitator superfamily
PNEKKDIO_03655 1.37e-47 yttA - - S - - - Pfam Transposase IS66
PNEKKDIO_03656 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
PNEKKDIO_03657 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_03658 1.52e-237 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
PNEKKDIO_03659 7.76e-168 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_03660 2.37e-138 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PNEKKDIO_03661 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PNEKKDIO_03662 1.99e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PNEKKDIO_03663 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
PNEKKDIO_03664 4.36e-208 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PNEKKDIO_03665 1.04e-43 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PNEKKDIO_03666 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
PNEKKDIO_03667 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PNEKKDIO_03668 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PNEKKDIO_03669 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PNEKKDIO_03670 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PNEKKDIO_03671 5.11e-49 ydaS - - S - - - membrane
PNEKKDIO_03672 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PNEKKDIO_03673 1.47e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PNEKKDIO_03674 3.33e-77 gtcA - - S - - - GtrA-like protein
PNEKKDIO_03675 3.42e-158 ywcC - - K - - - transcriptional regulator
PNEKKDIO_03677 1.75e-63 ywcB - - S - - - Protein of unknown function, DUF485
PNEKKDIO_03678 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PNEKKDIO_03679 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PNEKKDIO_03680 9.93e-305 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
PNEKKDIO_03681 5.43e-243 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
PNEKKDIO_03682 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
PNEKKDIO_03683 7.07e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PNEKKDIO_03684 5.16e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PNEKKDIO_03685 2.7e-203 ywbI - - K - - - Transcriptional regulator
PNEKKDIO_03686 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PNEKKDIO_03687 1.21e-143 ywbG - - M - - - effector of murein hydrolase
PNEKKDIO_03688 5.87e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
PNEKKDIO_03689 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
PNEKKDIO_03690 4.53e-52 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PNEKKDIO_03691 5.44e-214 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PNEKKDIO_03692 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
PNEKKDIO_03693 3.18e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PNEKKDIO_03694 8.79e-302 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PNEKKDIO_03695 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
PNEKKDIO_03696 0.0 yvrG - - T - - - Histidine kinase
PNEKKDIO_03697 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_03698 6.16e-33 - - - - - - - -
PNEKKDIO_03699 1.66e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PNEKKDIO_03700 3.46e-26 - - - S - - - YvrJ protein family
PNEKKDIO_03701 3.22e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PNEKKDIO_03702 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
PNEKKDIO_03703 2.76e-271 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PNEKKDIO_03704 1.33e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_03705 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
PNEKKDIO_03706 8.38e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PNEKKDIO_03707 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_03708 4.23e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_03709 1.81e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PNEKKDIO_03710 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
PNEKKDIO_03711 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
PNEKKDIO_03712 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
PNEKKDIO_03713 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PNEKKDIO_03714 1.16e-210 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
PNEKKDIO_03715 8.57e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
PNEKKDIO_03716 2.03e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
PNEKKDIO_03717 1.07e-201 yvgN - - S - - - reductase
PNEKKDIO_03718 7.12e-110 yvgO - - - - - - -
PNEKKDIO_03719 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
PNEKKDIO_03720 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PNEKKDIO_03721 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PNEKKDIO_03722 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PNEKKDIO_03723 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
PNEKKDIO_03724 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
PNEKKDIO_03725 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PNEKKDIO_03726 4.58e-85 ywnA - - K - - - Transcriptional regulator
PNEKKDIO_03727 5.89e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PNEKKDIO_03728 1.02e-76 ywnC - - S - - - Family of unknown function (DUF5362)
PNEKKDIO_03729 8.04e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
PNEKKDIO_03730 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PNEKKDIO_03731 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
PNEKKDIO_03732 1.01e-17 ywnC - - S - - - Family of unknown function (DUF5362)
PNEKKDIO_03733 1.81e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
PNEKKDIO_03734 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PNEKKDIO_03735 3.03e-44 ywnJ - - S - - - VanZ like family
PNEKKDIO_03736 2.45e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
PNEKKDIO_03737 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PNEKKDIO_03738 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
PNEKKDIO_03739 3.04e-102 - - - - - - - -
PNEKKDIO_03740 1.04e-133 yjgF - - Q - - - Isochorismatase family
PNEKKDIO_03741 3.79e-307 ywoD - - EGP - - - Major facilitator superfamily
PNEKKDIO_03742 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
PNEKKDIO_03743 1.88e-308 ywoF - - P - - - Right handed beta helix region
PNEKKDIO_03744 5.56e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_03745 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
PNEKKDIO_03746 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
PNEKKDIO_03747 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
PNEKKDIO_03748 1.02e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PNEKKDIO_03749 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PNEKKDIO_03750 1.01e-252 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
PNEKKDIO_03751 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PNEKKDIO_03752 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PNEKKDIO_03753 1.3e-192 ywpD - - T - - - Histidine kinase
PNEKKDIO_03754 2.21e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PNEKKDIO_03755 4.09e-44 ywpF - - S - - - YwpF-like protein
PNEKKDIO_03756 3.04e-87 ywpG - - - - - - -
PNEKKDIO_03757 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PNEKKDIO_03758 1.83e-234 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_03759 4.17e-109 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_03760 1.18e-90 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_03761 1.06e-196 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PNEKKDIO_03762 2.82e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
PNEKKDIO_03763 2.25e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
PNEKKDIO_03764 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PNEKKDIO_03766 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_03767 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PNEKKDIO_03768 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PNEKKDIO_03769 4.26e-308 steT - - E ko:K03294 - ko00000 amino acid
PNEKKDIO_03770 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
PNEKKDIO_03771 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
PNEKKDIO_03772 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
PNEKKDIO_03773 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
PNEKKDIO_03774 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PNEKKDIO_03775 8.12e-53 xhlB - - S - - - SPP1 phage holin
PNEKKDIO_03776 3.44e-45 xhlA - - S - - - Haemolysin XhlA
PNEKKDIO_03777 1.51e-198 xepA - - - - - - -
PNEKKDIO_03778 2.68e-32 xkdX - - - - - - -
PNEKKDIO_03779 8.68e-74 xkdW - - S - - - XkdW protein
PNEKKDIO_03780 4.73e-277 - - - - - - - -
PNEKKDIO_03781 1.18e-30 - - - - - - - -
PNEKKDIO_03782 4.43e-56 - - - - - - - -
PNEKKDIO_03783 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PNEKKDIO_03784 5.12e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PNEKKDIO_03785 1.33e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
PNEKKDIO_03786 1.24e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
PNEKKDIO_03787 1.34e-231 xkdQ - - G - - - NLP P60 protein
PNEKKDIO_03788 1.19e-156 xkdP - - S - - - Lysin motif
PNEKKDIO_03789 0.0 xkdO - - L - - - Transglycosylase SLT domain
PNEKKDIO_03790 1.25e-64 xkdO - - L - - - Transglycosylase SLT domain
PNEKKDIO_03791 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PNEKKDIO_03792 1.12e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
PNEKKDIO_03793 2.4e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PNEKKDIO_03794 1.53e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PNEKKDIO_03795 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PNEKKDIO_03796 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
PNEKKDIO_03797 3.59e-205 ykgA - - E - - - Amidinotransferase
PNEKKDIO_03798 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
PNEKKDIO_03799 5.13e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PNEKKDIO_03800 7.97e-167 ykjA - - S - - - Protein of unknown function (DUF421)
PNEKKDIO_03801 7.5e-127 ykkA - - S - - - Protein of unknown function (DUF664)
PNEKKDIO_03802 1.2e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PNEKKDIO_03803 1.04e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
PNEKKDIO_03804 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
PNEKKDIO_03805 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PNEKKDIO_03806 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PNEKKDIO_03807 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PNEKKDIO_03809 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
PNEKKDIO_03810 5.78e-97 ohrR - - K - - - COG1846 Transcriptional regulators
PNEKKDIO_03811 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
PNEKKDIO_03812 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
PNEKKDIO_03813 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PNEKKDIO_03814 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PNEKKDIO_03815 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PNEKKDIO_03816 4.44e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PNEKKDIO_03817 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PNEKKDIO_03818 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PNEKKDIO_03819 9.94e-142 ykoF - - S - - - YKOF-related Family
PNEKKDIO_03820 6.36e-161 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_03821 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
PNEKKDIO_03822 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
PNEKKDIO_03823 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PNEKKDIO_03824 5.59e-308 ymfH - - S - - - zinc protease
PNEKKDIO_03825 1.15e-299 albE - - S - - - Peptidase M16
PNEKKDIO_03826 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_03827 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_03828 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PNEKKDIO_03829 5.13e-132 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PNEKKDIO_03830 4.94e-44 - - - S - - - YlzJ-like protein
PNEKKDIO_03831 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
PNEKKDIO_03832 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PNEKKDIO_03833 5.25e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PNEKKDIO_03834 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PNEKKDIO_03835 5.86e-75 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PNEKKDIO_03836 4.62e-153 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PNEKKDIO_03837 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PNEKKDIO_03838 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
PNEKKDIO_03839 1.53e-56 ymxH - - S - - - YlmC YmxH family
PNEKKDIO_03840 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
PNEKKDIO_03841 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
PNEKKDIO_03842 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PNEKKDIO_03843 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PNEKKDIO_03844 9.04e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PNEKKDIO_03845 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PNEKKDIO_03846 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PNEKKDIO_03847 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
PNEKKDIO_03848 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PNEKKDIO_03849 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
PNEKKDIO_03850 1.49e-180 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
PNEKKDIO_03851 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
PNEKKDIO_03852 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
PNEKKDIO_03853 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
PNEKKDIO_03854 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PNEKKDIO_03855 1.64e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
PNEKKDIO_03856 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PNEKKDIO_03857 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PNEKKDIO_03858 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
PNEKKDIO_03859 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PNEKKDIO_03860 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PNEKKDIO_03861 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PNEKKDIO_03862 5.18e-81 yqhP - - - - - - -
PNEKKDIO_03863 5.54e-140 yqhQ - - S - - - Protein of unknown function (DUF1385)
PNEKKDIO_03864 2.06e-63 yqhQ - - S - - - Protein of unknown function (DUF1385)
PNEKKDIO_03865 1.14e-120 yqhR - - S - - - Conserved membrane protein YqhR
PNEKKDIO_03866 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
PNEKKDIO_03867 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PNEKKDIO_03868 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PNEKKDIO_03869 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
PNEKKDIO_03870 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
PNEKKDIO_03871 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
PNEKKDIO_03872 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
PNEKKDIO_03873 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
PNEKKDIO_03874 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
PNEKKDIO_03875 6.92e-89 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
PNEKKDIO_03876 7.28e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
PNEKKDIO_03877 1.43e-119 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
PNEKKDIO_03878 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PNEKKDIO_03879 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PNEKKDIO_03880 1.65e-88 yqhY - - S - - - protein conserved in bacteria
PNEKKDIO_03881 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PNEKKDIO_03882 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PNEKKDIO_03883 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PNEKKDIO_03884 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PNEKKDIO_03885 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PNEKKDIO_03886 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PNEKKDIO_03887 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PNEKKDIO_03888 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PNEKKDIO_03889 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PNEKKDIO_03890 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PNEKKDIO_03891 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PNEKKDIO_03892 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PNEKKDIO_03893 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PNEKKDIO_03894 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PNEKKDIO_03895 4.02e-86 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PNEKKDIO_03896 3.86e-44 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PNEKKDIO_03897 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PNEKKDIO_03898 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PNEKKDIO_03899 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PNEKKDIO_03900 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
PNEKKDIO_03901 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PNEKKDIO_03902 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PNEKKDIO_03903 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PNEKKDIO_03904 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PNEKKDIO_03905 1.42e-75 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
PNEKKDIO_03906 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PNEKKDIO_03907 1.49e-148 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
PNEKKDIO_03908 5.73e-37 - - - S - - - Transcriptional Coactivator p15 (PC4)
PNEKKDIO_03910 4.07e-74 - - - S - - - Protein of unknown function, DUF600
PNEKKDIO_03911 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
PNEKKDIO_03912 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
PNEKKDIO_03913 1.49e-272 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
PNEKKDIO_03915 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
PNEKKDIO_03917 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_03918 1.42e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
PNEKKDIO_03919 1.23e-195 yesF - - GM - - - NAD(P)H-binding
PNEKKDIO_03920 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
PNEKKDIO_03921 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
PNEKKDIO_03922 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
PNEKKDIO_03923 9.4e-128 yesJ - - K - - - Acetyltransferase (GNAT) family
PNEKKDIO_03925 1.48e-131 yesL - - S - - - Protein of unknown function, DUF624
PNEKKDIO_03926 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PNEKKDIO_03927 1.98e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
PNEKKDIO_03928 9.72e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PNEKKDIO_03929 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_03930 1.2e-208 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PNEKKDIO_03931 1.03e-240 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
PNEKKDIO_03932 0.0 yesS - - K - - - Transcriptional regulator
PNEKKDIO_03933 5.02e-86 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PNEKKDIO_03934 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PNEKKDIO_03935 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PNEKKDIO_03936 0.0 ywqB - - S - - - SWIM zinc finger
PNEKKDIO_03937 3.6e-25 - - - - - - - -
PNEKKDIO_03938 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
PNEKKDIO_03939 4.64e-73 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PNEKKDIO_03940 5.43e-56 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PNEKKDIO_03941 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
PNEKKDIO_03942 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PNEKKDIO_03943 5.95e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
PNEKKDIO_03945 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
PNEKKDIO_03946 7.13e-303 ywqJ - - S - - - Pre-toxin TG
PNEKKDIO_03948 3.56e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PNEKKDIO_03949 4.73e-209 - - - K - - - Transcriptional regulator
PNEKKDIO_03950 3.55e-11 ywqN - - S - - - NAD(P)H-dependent
PNEKKDIO_03951 2.28e-104 ywqN - - S - - - NAD(P)H-dependent
PNEKKDIO_03953 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
PNEKKDIO_03954 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
PNEKKDIO_03955 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PNEKKDIO_03956 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PNEKKDIO_03957 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
PNEKKDIO_03958 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PNEKKDIO_03959 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PNEKKDIO_03960 1.79e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PNEKKDIO_03961 6.9e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PNEKKDIO_03962 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PNEKKDIO_03963 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PNEKKDIO_03964 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PNEKKDIO_03965 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
PNEKKDIO_03966 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PNEKKDIO_03967 3.29e-144 ccpN - - K - - - CBS domain
PNEKKDIO_03968 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PNEKKDIO_03969 2.06e-16 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PNEKKDIO_03970 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PNEKKDIO_03971 1.76e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PNEKKDIO_03972 5.29e-27 - - - S - - - YqzL-like protein
PNEKKDIO_03973 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PNEKKDIO_03974 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PNEKKDIO_03975 1.53e-76 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PNEKKDIO_03976 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PNEKKDIO_03977 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
PNEKKDIO_03978 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
PNEKKDIO_03979 9.09e-109 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PNEKKDIO_03980 1.07e-83 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PNEKKDIO_03981 2.07e-60 yqfC - - S - - - sporulation protein YqfC
PNEKKDIO_03982 1.04e-35 yqfB - - - - - - -
PNEKKDIO_03983 2.46e-141 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
PNEKKDIO_03984 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
PNEKKDIO_03985 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PNEKKDIO_03986 6.1e-276 xylR - - GK - - - ROK family
PNEKKDIO_03987 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PNEKKDIO_03988 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
PNEKKDIO_03989 4.15e-108 - - - E - - - phosphoribosylanthranilate isomerase activity
PNEKKDIO_03992 7.71e-143 - - - S - - - Domain of unknown function (DUF3885)
PNEKKDIO_03993 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PNEKKDIO_03995 1.61e-93 - - - S - - - CAAX protease self-immunity
PNEKKDIO_03996 4.03e-104 ynaD - - J - - - Acetyltransferase (GNAT) domain
PNEKKDIO_03998 9e-274 - - - H - - - N-terminal domain of galactosyltransferase
PNEKKDIO_03999 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_04000 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
PNEKKDIO_04001 9.6e-120 - - - M - - - Glycosyltransferase like family
PNEKKDIO_04002 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PNEKKDIO_04003 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PNEKKDIO_04004 1.71e-143 ykoX - - S - - - membrane-associated protein
PNEKKDIO_04005 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
PNEKKDIO_04006 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PNEKKDIO_04007 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
PNEKKDIO_04008 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PNEKKDIO_04009 0.0 ykoS - - - - - - -
PNEKKDIO_04010 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PNEKKDIO_04011 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
PNEKKDIO_04012 6.08e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PNEKKDIO_04013 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
PNEKKDIO_04014 3.04e-36 ykoL - - - - - - -
PNEKKDIO_04015 1.63e-25 - - - - - - - -
PNEKKDIO_04016 1.49e-70 tnrA - - K - - - transcriptional
PNEKKDIO_04017 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
PNEKKDIO_04019 1.45e-08 - - - - - - - -
PNEKKDIO_04020 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
PNEKKDIO_04021 8.79e-47 ykoI - - S - - - Peptidase propeptide and YPEB domain
PNEKKDIO_04022 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PNEKKDIO_04023 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PNEKKDIO_04024 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PNEKKDIO_04025 1.09e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
PNEKKDIO_04026 3.43e-128 yqjB - - S - - - protein conserved in bacteria
PNEKKDIO_04028 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
PNEKKDIO_04029 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PNEKKDIO_04030 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
PNEKKDIO_04031 8.09e-180 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
PNEKKDIO_04032 5.11e-162 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PNEKKDIO_04033 7.57e-192 - 6.2.1.3 - IQ ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PNEKKDIO_04034 1.06e-303 - 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PNEKKDIO_04035 1.63e-127 - 1.1.1.100 - IQ ko:K00059,ko:K07535 ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PNEKKDIO_04036 3.08e-22 - - - IQ - - - Phosphopantetheine attachment site
PNEKKDIO_04037 4.05e-204 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNEKKDIO_04038 4.49e-176 - - - I - - - Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PNEKKDIO_04039 2.05e-86 yodA - - S - - - tautomerase
PNEKKDIO_04040 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
PNEKKDIO_04041 1.17e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PNEKKDIO_04042 3.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
PNEKKDIO_04043 9.34e-176 azlC - - E - - - AzlC protein
PNEKKDIO_04044 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
PNEKKDIO_04045 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PNEKKDIO_04046 1.01e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PNEKKDIO_04048 1.01e-130 yrdC - - Q - - - Isochorismatase family
PNEKKDIO_04049 2.44e-72 - - - S - - - Protein of unknown function (DUF2568)
PNEKKDIO_04050 5.77e-118 yrdA - - S - - - DinB family
PNEKKDIO_04051 4.23e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
PNEKKDIO_04052 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PNEKKDIO_04054 7.23e-180 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PNEKKDIO_04055 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
PNEKKDIO_04056 7.71e-114 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
PNEKKDIO_04057 4.48e-102 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
PNEKKDIO_04058 5.29e-198 yndG - - S - - - DoxX-like family
PNEKKDIO_04059 1.69e-148 - - - S - - - Domain of unknown function (DUF4166)
PNEKKDIO_04060 0.0 yndJ - - S - - - YndJ-like protein
PNEKKDIO_04062 1.88e-174 yndL - - S - - - Replication protein
PNEKKDIO_04063 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
PNEKKDIO_04064 1.52e-83 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PNEKKDIO_04065 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PNEKKDIO_04066 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PNEKKDIO_04067 2.29e-144 yneB - - L - - - resolvase
PNEKKDIO_04068 1.15e-43 ynzC - - S - - - UPF0291 protein
PNEKKDIO_04069 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PNEKKDIO_04070 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
PNEKKDIO_04071 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
PNEKKDIO_04072 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
PNEKKDIO_04073 4.04e-128 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PNEKKDIO_04074 3e-09 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PNEKKDIO_04075 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
PNEKKDIO_04076 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
PNEKKDIO_04077 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
PNEKKDIO_04078 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
PNEKKDIO_04079 2.6e-233 yaaC - - S - - - YaaC-like Protein
PNEKKDIO_04080 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PNEKKDIO_04081 7.51e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PNEKKDIO_04082 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PNEKKDIO_04083 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PNEKKDIO_04084 3.98e-295 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PNEKKDIO_04086 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
PNEKKDIO_04087 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
PNEKKDIO_04088 1.22e-274 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
PNEKKDIO_04089 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
PNEKKDIO_04090 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PNEKKDIO_04091 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PNEKKDIO_04092 7.32e-204 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_04094 5.73e-243 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PNEKKDIO_04095 4.83e-50 - - - S - - - Bacteriophage holin
PNEKKDIO_04097 2.37e-93 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PNEKKDIO_04098 2.92e-55 - - - S - - - virus tail, fiber
PNEKKDIO_04099 1.35e-142 - - - - - - - -
PNEKKDIO_04100 0.0 - - - S - - - Pfam Transposase IS66
PNEKKDIO_04101 2.16e-109 - - - S - - - Phage tail protein
PNEKKDIO_04102 1.81e-153 - - - S - - - peptidoglycan catabolic process
PNEKKDIO_04103 7.38e-22 - - - S - - - peptidoglycan catabolic process
PNEKKDIO_04120 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
PNEKKDIO_04121 1.58e-36 - - - - - - - -
PNEKKDIO_04122 2.61e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PNEKKDIO_04123 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PNEKKDIO_04124 0.0 ygaK - - C - - - Berberine and berberine like
PNEKKDIO_04126 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PNEKKDIO_04127 1.96e-186 ydbA - - P - - - EcsC protein family
PNEKKDIO_04128 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PNEKKDIO_04129 1.67e-42 ydaS - - S - - - membrane
PNEKKDIO_04130 3.2e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PNEKKDIO_04131 2.5e-52 - - - - - - - -
PNEKKDIO_04133 1.9e-91 sdpB - - S - - - Protein conserved in bacteria
PNEKKDIO_04134 1.84e-34 - - - - - - - -
PNEKKDIO_04136 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PNEKKDIO_04137 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PNEKKDIO_04138 0.0 ydaO - - E - - - amino acid
PNEKKDIO_04139 6.61e-146 ydaN - - S - - - Bacterial cellulose synthase subunit
PNEKKDIO_04140 3.36e-265 - - - Q ko:K15662 ko01054,map01054 ko00000,ko00001,ko01008 Non-ribosomal peptide synthetase modules and related proteins
PNEKKDIO_04141 1.25e-286 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PNEKKDIO_04142 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
PNEKKDIO_04143 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PNEKKDIO_04144 1.82e-192 ybbH - - K - - - transcriptional
PNEKKDIO_04145 1.35e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PNEKKDIO_04146 3.13e-114 ybbJ - - J - - - acetyltransferase
PNEKKDIO_04147 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
PNEKKDIO_04153 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PNEKKDIO_04154 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PNEKKDIO_04155 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PNEKKDIO_04156 2.58e-92 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
PNEKKDIO_04157 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
PNEKKDIO_04158 1.34e-201 - - - K - - - Transcriptional regulator
PNEKKDIO_04159 4.21e-217 yrdR - - EG - - - EamA-like transporter family
PNEKKDIO_04160 2.45e-23 - - - S - - - YrzO-like protein
PNEKKDIO_04161 5.23e-262 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PNEKKDIO_04162 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
PNEKKDIO_04163 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PNEKKDIO_04164 5.9e-193 bltR - - K - - - helix_turn_helix, mercury resistance
PNEKKDIO_04165 2.21e-138 yrkC - - G - - - Cupin domain
PNEKKDIO_04166 4.38e-52 yrkD - - S - - - protein conserved in bacteria
PNEKKDIO_04167 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
PNEKKDIO_04168 4.51e-99 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PNEKKDIO_04169 6.68e-302 ybbC - - S - - - protein conserved in bacteria
PNEKKDIO_04170 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PNEKKDIO_04171 2.45e-174 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
PNEKKDIO_04172 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PNEKKDIO_04173 3.46e-176 ybbA - - S ko:K07017 - ko00000 Putative esterase
PNEKKDIO_04174 1.87e-203 ybaS - - S - - - Na -dependent transporter
PNEKKDIO_04176 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PNEKKDIO_04179 5.19e-86 - - - - - - - -
PNEKKDIO_04182 4.47e-87 - - - - - - - -
PNEKKDIO_04183 3.61e-117 - - - - - - - -
PNEKKDIO_04184 2.4e-169 - - - - - - - -
PNEKKDIO_04185 5.27e-144 - - - - - - - -
PNEKKDIO_04188 5.66e-70 - - - - - - - -
PNEKKDIO_04189 7.47e-35 - - - - - - - -
PNEKKDIO_04192 1.54e-26 - - - - - - - -
PNEKKDIO_04193 1.7e-25 - - - - - - - -
PNEKKDIO_04194 1.24e-85 - - - - - - - -
PNEKKDIO_04195 4.75e-245 - - - A - - - Belongs to the 'phage' integrase family
PNEKKDIO_04198 2.72e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PNEKKDIO_04199 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
PNEKKDIO_04200 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
PNEKKDIO_04201 0.0 yqbA - - S - - - portal protein
PNEKKDIO_04202 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
PNEKKDIO_04203 3.91e-217 xkdG - - S - - - Phage capsid family
PNEKKDIO_04204 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
PNEKKDIO_04205 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
PNEKKDIO_04206 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
PNEKKDIO_04207 2.87e-101 xkdJ - - - - - - -
PNEKKDIO_04208 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
PNEKKDIO_04209 6.01e-99 xkdM - - S - - - Phage tail tube protein
PNEKKDIO_04210 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
PNEKKDIO_04211 3.78e-166 - - - E - - - GDSL-like Lipase/Acylhydrolase
PNEKKDIO_04212 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
PNEKKDIO_04213 9.47e-144 - - - S - - - Protein of unknown function, DUF624
PNEKKDIO_04214 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PNEKKDIO_04215 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PNEKKDIO_04216 5.77e-141 - - - E - - - GDSL-like Lipase/Acylhydrolase
PNEKKDIO_04217 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
PNEKKDIO_04218 3.73e-70 - - - K - - - DNA binding
PNEKKDIO_04222 1.56e-45 - - - - - - - -
PNEKKDIO_04225 3.29e-41 - - - - - - - -
PNEKKDIO_04226 7.52e-17 bet - - L - - - RecT family
PNEKKDIO_04227 2.78e-22 - - - - - - - -
PNEKKDIO_04228 1.62e-15 - - - - - - - -
PNEKKDIO_04230 9.75e-16 - - - K - - - Helix-turn-helix XRE-family like proteins
PNEKKDIO_04231 2.82e-65 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
PNEKKDIO_04232 2.21e-28 - - - - - - - -
PNEKKDIO_04234 2.75e-35 - - - L - - - Phage integrase family
PNEKKDIO_04235 3.34e-39 - - - L - - - Phage integrase family
PNEKKDIO_04238 4.96e-49 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PNEKKDIO_04240 1.07e-265 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
PNEKKDIO_04244 1.55e-130 - - - - - - - -
PNEKKDIO_04250 4.59e-92 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PNEKKDIO_04251 1.31e-48 - - - O - - - Glutaredoxin
PNEKKDIO_04252 1.91e-232 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEKKDIO_04254 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEKKDIO_04255 4.05e-139 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PNEKKDIO_04256 1.09e-82 - - - S - - - NrdI Flavodoxin like
PNEKKDIO_04263 1.27e-196 - - - L - - - Domain of unknown function (DUF4942)
PNEKKDIO_04264 1.34e-22 - - - L - - - Domain of unknown function (DUF4942)
PNEKKDIO_04271 1.79e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PNEKKDIO_04273 1.56e-112 - - - - - - - -
PNEKKDIO_04279 2.37e-151 - - - - - - - -
PNEKKDIO_04281 1.59e-209 - - - S - - - Thymidylate synthase
PNEKKDIO_04283 2.11e-170 - - - S - - - Domain of unknown function, YrpD
PNEKKDIO_04286 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
PNEKKDIO_04287 8.92e-96 - - - - - - - -
PNEKKDIO_04288 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
PNEKKDIO_04291 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PNEKKDIO_04292 2.69e-104 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
PNEKKDIO_04293 3.52e-126 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
PNEKKDIO_04296 1.59e-115 - - - S - - - Protein of unknown function (DUF1273)
PNEKKDIO_04297 2.71e-17 - - - S - - - YopX protein
PNEKKDIO_04299 9.71e-12 - - - S - - - YopX protein
PNEKKDIO_04302 7.36e-97 - - - - - - - -
PNEKKDIO_04305 2.22e-191 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
PNEKKDIO_04306 2.03e-133 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PNEKKDIO_04308 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PNEKKDIO_04309 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PNEKKDIO_04310 6.41e-284 - - - L - - - DNA primase activity
PNEKKDIO_04311 4.75e-171 - - - J - - - DnaB-like helicase C terminal domain
PNEKKDIO_04322 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PNEKKDIO_04323 2.89e-226 - - - - - - - -
PNEKKDIO_04324 2.31e-42 - - - S - - - DNA-sulfur modification-associated
PNEKKDIO_04325 1.71e-251 - - - S - - - DNA-sulfur modification-associated
PNEKKDIO_04326 5.48e-209 - - - L - - - Belongs to the 'phage' integrase family
PNEKKDIO_04327 1.49e-70 - - - S - - - YolD-like protein
PNEKKDIO_04328 2.3e-71 - - - L - - - nuclease activity
PNEKKDIO_04329 7.82e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PNEKKDIO_04330 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PNEKKDIO_04331 4.94e-25 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PNEKKDIO_04332 5.86e-152 - - - V - - - HNH endonuclease
PNEKKDIO_04333 2.02e-81 - - - G - - - SMI1-KNR4 cell-wall
PNEKKDIO_04334 1.1e-46 - - - - - - - -
PNEKKDIO_04338 1.44e-107 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEKKDIO_04339 9.85e-57 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PNEKKDIO_04341 5.19e-18 - - - S - - - SNARE associated Golgi protein
PNEKKDIO_04342 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
PNEKKDIO_04343 2.66e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PNEKKDIO_04344 1.07e-46 ypuD - - - - - - -
PNEKKDIO_04345 1.32e-94 - - - - - - - -
PNEKKDIO_04346 2.8e-27 - - - - - - - -
PNEKKDIO_04347 0.0 - - - - - - - -
PNEKKDIO_04349 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PNEKKDIO_04350 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
PNEKKDIO_04352 2.34e-41 - - - - - - - -
PNEKKDIO_04354 1.86e-23 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PNEKKDIO_04356 3.42e-55 - - - - - - - -
PNEKKDIO_04357 4.47e-244 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
PNEKKDIO_04358 0.000327 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PNEKKDIO_04360 2.4e-76 - - - - - - - -
PNEKKDIO_04373 9.26e-119 - - - S - - - methyltransferase activity
PNEKKDIO_04374 2.63e-104 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
PNEKKDIO_04379 1.18e-64 - - - S - - - protein conserved in bacteria
PNEKKDIO_04380 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
PNEKKDIO_04381 9.02e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PNEKKDIO_04382 3.4e-258 yaaN - - P - - - Belongs to the TelA family
PNEKKDIO_04383 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
PNEKKDIO_04384 2.44e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PNEKKDIO_04389 1.24e-162 - - - - - - - -
PNEKKDIO_04391 5.03e-43 yoaF - - - - - - -
PNEKKDIO_04394 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
PNEKKDIO_04396 3.69e-111 - - - - - - - -
PNEKKDIO_04397 6.35e-229 - - - L - - - AAA domain
PNEKKDIO_04398 1.48e-197 - - - - - - - -
PNEKKDIO_04403 2.85e-66 - - - M - - - Parallel beta-helix repeats
PNEKKDIO_04404 3.41e-161 - - - Q - - - Thioesterase domain
PNEKKDIO_04406 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PNEKKDIO_04407 1.77e-32 yqzJ - - - - - - -
PNEKKDIO_04408 1.06e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PNEKKDIO_04409 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PNEKKDIO_04410 2.95e-14 - - - - - - - -
PNEKKDIO_04412 1.05e-112 - - - - - - - -
PNEKKDIO_04413 2.41e-07 - - - S - - - nucleic acid binding
PNEKKDIO_04414 0.0 - - - - - - - -
PNEKKDIO_04416 3.95e-127 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
PNEKKDIO_04417 0.000112 perX - - S - - - DsrE/DsrF-like family
PNEKKDIO_04418 2.94e-263 yrkH - - P - - - Rhodanese Homology Domain
PNEKKDIO_04419 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
PNEKKDIO_04420 3.28e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
PNEKKDIO_04421 3.07e-67 - - - M - - - Parallel beta-helix repeats
PNEKKDIO_04422 1.88e-302 - - - M - - - Parallel beta-helix repeats
PNEKKDIO_04423 3.39e-188 - - - S - - - Pfam:DUF867
PNEKKDIO_04425 3.63e-95 - - - - - - - -
PNEKKDIO_04429 2.02e-258 - - - - - - - -
PNEKKDIO_04430 1.27e-118 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PNEKKDIO_04431 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PNEKKDIO_04432 1.17e-47 - - - S - - - Protein of unknown function (DUF1433)
PNEKKDIO_04433 3.12e-109 - - - I - - - Pfam Lipase (class 3)
PNEKKDIO_04434 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PNEKKDIO_04435 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_04436 2.91e-20 - - - L ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
PNEKKDIO_04437 2.23e-164 - - - S - - - peptidoglycan catabolic process
PNEKKDIO_04439 2.88e-37 - - - - - - - -
PNEKKDIO_04440 1.06e-57 - - - S - - - Pfam Transposase IS66
PNEKKDIO_04441 1.11e-21 csbD - - K - - - CsbD-like
PNEKKDIO_04442 1.12e-109 ywmF - - S - - - Peptidase M50
PNEKKDIO_04443 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PNEKKDIO_04444 6.87e-131 - - - I - - - Pfam Lipase (class 3)
PNEKKDIO_04445 2.2e-42 - - - - - - - -
PNEKKDIO_04447 2.27e-22 - - - K - - - Helix-turn-helix domain
PNEKKDIO_04449 6.8e-65 ykoH - - T - - - Histidine kinase
PNEKKDIO_04450 4.46e-216 ykoH - - T - - - Histidine kinase
PNEKKDIO_04451 1.34e-46 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PNEKKDIO_04452 3.6e-23 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_04453 1.78e-159 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_04454 3.08e-56 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PNEKKDIO_04455 3.21e-107 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 DNA specificity domain
PNEKKDIO_04458 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
PNEKKDIO_04459 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
PNEKKDIO_04460 7.34e-120 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PNEKKDIO_04461 2.23e-37 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PNEKKDIO_04466 8.42e-13 - - - K - - - Cro/C1-type HTH DNA-binding domain
PNEKKDIO_04479 1.2e-94 - - - S - - - Protein of unknown function (DUF3800)
PNEKKDIO_04483 9.59e-19 - - - S - - - Phage tail protein
PNEKKDIO_04488 0.00069 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PNEKKDIO_04495 5.73e-29 - - - K - - - Cro/C1-type HTH DNA-binding domain
PNEKKDIO_04496 6.7e-84 - - - - - - - -
PNEKKDIO_04497 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)