ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MLHCIMPN_00001 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MLHCIMPN_00004 8.24e-234 yaaC - - S - - - YaaC-like Protein
MLHCIMPN_00005 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLHCIMPN_00006 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLHCIMPN_00007 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLHCIMPN_00008 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLHCIMPN_00009 1.3e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLHCIMPN_00010 1.9e-257 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MLHCIMPN_00012 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MLHCIMPN_00013 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MLHCIMPN_00014 5.59e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MLHCIMPN_00015 1.44e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MLHCIMPN_00016 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLHCIMPN_00017 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLHCIMPN_00018 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLHCIMPN_00019 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLHCIMPN_00020 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
MLHCIMPN_00021 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MLHCIMPN_00022 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MLHCIMPN_00023 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
MLHCIMPN_00024 7.19e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLHCIMPN_00025 2.32e-242 yaaN - - P - - - Belongs to the TelA family
MLHCIMPN_00026 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MLHCIMPN_00027 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLHCIMPN_00028 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
MLHCIMPN_00029 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MLHCIMPN_00030 1.9e-233 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MLHCIMPN_00031 9e-189 yaaT - - S - - - stage 0 sporulation protein
MLHCIMPN_00032 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
MLHCIMPN_00033 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MLHCIMPN_00034 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MLHCIMPN_00035 1.65e-209 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLHCIMPN_00036 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MLHCIMPN_00037 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLHCIMPN_00038 1.02e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MLHCIMPN_00039 3.23e-306 yabE - - T - - - protein conserved in bacteria
MLHCIMPN_00040 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLHCIMPN_00041 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLHCIMPN_00042 6.71e-208 yabG - - S ko:K06436 - ko00000 peptidase
MLHCIMPN_00043 3.08e-52 veg - - S - - - protein conserved in bacteria
MLHCIMPN_00044 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
MLHCIMPN_00045 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLHCIMPN_00046 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MLHCIMPN_00047 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MLHCIMPN_00048 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLHCIMPN_00049 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLHCIMPN_00050 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLHCIMPN_00051 3.57e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLHCIMPN_00052 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLHCIMPN_00053 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
MLHCIMPN_00054 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLHCIMPN_00055 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MLHCIMPN_00056 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_00057 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLHCIMPN_00058 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLHCIMPN_00059 5.47e-66 yabP - - S - - - Sporulation protein YabP
MLHCIMPN_00060 1.95e-133 yabQ - - S - - - spore cortex biosynthesis protein
MLHCIMPN_00061 6.94e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MLHCIMPN_00062 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MLHCIMPN_00065 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MLHCIMPN_00066 5.38e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLHCIMPN_00067 3.3e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLHCIMPN_00068 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLHCIMPN_00069 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MLHCIMPN_00070 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLHCIMPN_00071 6.64e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLHCIMPN_00072 1.3e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLHCIMPN_00073 1.16e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MLHCIMPN_00074 2.09e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLHCIMPN_00075 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLHCIMPN_00076 2.97e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MLHCIMPN_00077 2.83e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MLHCIMPN_00078 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLHCIMPN_00079 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLHCIMPN_00080 3.34e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLHCIMPN_00081 8.67e-40 yazB - - K - - - transcriptional
MLHCIMPN_00082 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHCIMPN_00083 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MLHCIMPN_00090 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00091 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00092 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00093 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MLHCIMPN_00094 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MLHCIMPN_00095 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLHCIMPN_00096 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MLHCIMPN_00097 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLHCIMPN_00098 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLHCIMPN_00099 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MLHCIMPN_00100 2.38e-158 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLHCIMPN_00101 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLHCIMPN_00102 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLHCIMPN_00103 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MLHCIMPN_00104 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MLHCIMPN_00105 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLHCIMPN_00106 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHCIMPN_00107 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MLHCIMPN_00108 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MLHCIMPN_00109 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLHCIMPN_00110 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLHCIMPN_00111 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLHCIMPN_00112 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLHCIMPN_00113 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLHCIMPN_00114 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLHCIMPN_00115 1.2e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MLHCIMPN_00116 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHCIMPN_00117 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHCIMPN_00118 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MLHCIMPN_00119 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLHCIMPN_00120 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLHCIMPN_00121 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLHCIMPN_00122 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLHCIMPN_00123 2.33e-239 ybaC - - S - - - Alpha/beta hydrolase family
MLHCIMPN_00124 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MLHCIMPN_00125 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLHCIMPN_00126 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MLHCIMPN_00127 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLHCIMPN_00128 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLHCIMPN_00129 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLHCIMPN_00130 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLHCIMPN_00131 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLHCIMPN_00132 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLHCIMPN_00133 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MLHCIMPN_00134 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLHCIMPN_00135 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLHCIMPN_00136 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLHCIMPN_00137 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLHCIMPN_00138 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHCIMPN_00139 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLHCIMPN_00140 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLHCIMPN_00141 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLHCIMPN_00142 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLHCIMPN_00143 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MLHCIMPN_00144 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MLHCIMPN_00145 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLHCIMPN_00146 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLHCIMPN_00147 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MLHCIMPN_00148 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLHCIMPN_00149 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MLHCIMPN_00150 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLHCIMPN_00151 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLHCIMPN_00152 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLHCIMPN_00153 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MLHCIMPN_00154 1.45e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHCIMPN_00155 2.09e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHCIMPN_00156 7.93e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLHCIMPN_00157 3.56e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLHCIMPN_00158 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLHCIMPN_00159 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MLHCIMPN_00160 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
MLHCIMPN_00161 9.4e-110 yizA - - S - - - Damage-inducible protein DinB
MLHCIMPN_00162 9.25e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
MLHCIMPN_00163 2.31e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLHCIMPN_00164 9e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLHCIMPN_00165 1.95e-102 gerD - - - ko:K06294 - ko00000 -
MLHCIMPN_00166 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MLHCIMPN_00167 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
MLHCIMPN_00169 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_00171 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_00172 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_00173 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_00174 1.22e-57 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
MLHCIMPN_00177 7.54e-07 - - - S - - - domain, Protein
MLHCIMPN_00179 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLHCIMPN_00180 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLHCIMPN_00181 5.87e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MLHCIMPN_00182 1.65e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MLHCIMPN_00183 1.4e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLHCIMPN_00184 1.74e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLHCIMPN_00185 4.77e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MLHCIMPN_00186 2.82e-155 yflK - - S - - - protein conserved in bacteria
MLHCIMPN_00187 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
MLHCIMPN_00188 1.98e-26 yflI - - - - - - -
MLHCIMPN_00189 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
MLHCIMPN_00190 9.02e-176 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MLHCIMPN_00191 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLHCIMPN_00192 2.02e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MLHCIMPN_00193 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MLHCIMPN_00194 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MLHCIMPN_00195 1.18e-103 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHCIMPN_00196 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
MLHCIMPN_00197 5.99e-50 ydgB - - S - - - Spore germination protein gerPA/gerPF
MLHCIMPN_00198 1.57e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_00199 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLHCIMPN_00200 1.18e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MLHCIMPN_00201 2.93e-158 frp - - C - - - nitroreductase
MLHCIMPN_00202 6e-167 yibF - - S - - - YibE/F-like protein
MLHCIMPN_00203 1.02e-246 yibE - - S - - - YibE/F-like protein
MLHCIMPN_00204 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MLHCIMPN_00205 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MLHCIMPN_00206 6.43e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MLHCIMPN_00207 5.86e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHCIMPN_00208 3.38e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLHCIMPN_00209 6.98e-252 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_00210 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
MLHCIMPN_00211 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLHCIMPN_00212 3.7e-70 yfkI - - S - - - gas vesicle protein
MLHCIMPN_00213 1.95e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MLHCIMPN_00214 6.71e-12 - - - - - - - -
MLHCIMPN_00215 4.6e-265 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_00216 1.4e-237 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MLHCIMPN_00217 1.62e-185 yfkD - - S - - - YfkD-like protein
MLHCIMPN_00218 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
MLHCIMPN_00219 2.92e-282 yfkA - - S - - - YfkB-like domain
MLHCIMPN_00220 7.99e-37 yfjT - - - - - - -
MLHCIMPN_00221 3.59e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MLHCIMPN_00222 4.82e-184 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHCIMPN_00223 1.12e-103 - - - S ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacitracin ABC transporter permease
MLHCIMPN_00224 8.75e-92 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
MLHCIMPN_00225 4.57e-138 - - - K - - - Two component transcriptional regulator, winged helix family
MLHCIMPN_00226 2.8e-139 - - - T - - - His Kinase A (phosphoacceptor) domain
MLHCIMPN_00227 1.09e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLHCIMPN_00229 3.71e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MLHCIMPN_00230 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLHCIMPN_00231 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHCIMPN_00232 1.64e-62 - - - S - - - YfzA-like protein
MLHCIMPN_00233 3.47e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLHCIMPN_00234 6.01e-115 yfjM - - S - - - Psort location Cytoplasmic, score
MLHCIMPN_00235 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHCIMPN_00236 1.52e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHCIMPN_00237 5.38e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHCIMPN_00238 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHCIMPN_00239 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MLHCIMPN_00240 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MLHCIMPN_00241 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLHCIMPN_00242 9.01e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MLHCIMPN_00243 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_00244 3.72e-228 yobO - - M - - - COG5434 Endopolygalacturonase
MLHCIMPN_00245 1.89e-279 yobO - - M - - - COG5434 Endopolygalacturonase
MLHCIMPN_00246 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLHCIMPN_00247 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHCIMPN_00248 5.54e-82 yfiD3 - - S - - - DoxX
MLHCIMPN_00249 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MLHCIMPN_00250 7.58e-217 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLHCIMPN_00251 5.62e-126 padR - - K - - - transcriptional
MLHCIMPN_00252 1.79e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLHCIMPN_00253 7.69e-236 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLHCIMPN_00254 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MLHCIMPN_00255 2.36e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MLHCIMPN_00256 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MLHCIMPN_00257 0.0 yfiU - - EGP - - - the major facilitator superfamily
MLHCIMPN_00258 7.97e-108 yfiV - - K - - - transcriptional
MLHCIMPN_00259 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLHCIMPN_00260 7.26e-209 yfhB - - S - - - PhzF family
MLHCIMPN_00261 1.94e-136 yfhC - - C - - - nitroreductase
MLHCIMPN_00262 3.61e-34 yfhD - - S - - - YfhD-like protein
MLHCIMPN_00264 3.34e-212 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MLHCIMPN_00265 3.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MLHCIMPN_00266 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
MLHCIMPN_00267 2.86e-268 yfhI - - EGP - - - -transporter
MLHCIMPN_00269 3.34e-214 mpr - - M - - - Belongs to the peptidase S1B family
MLHCIMPN_00270 2.57e-59 yfhJ - - S - - - WVELL protein
MLHCIMPN_00271 3.85e-120 yfhK - - T - - - Bacterial SH3 domain homologues
MLHCIMPN_00272 2.99e-57 yfhL - - S - - - SdpI/YhfL protein family
MLHCIMPN_00273 6.8e-219 - - - S - - - Alpha/beta hydrolase family
MLHCIMPN_00274 1.57e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHCIMPN_00275 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MLHCIMPN_00276 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MLHCIMPN_00277 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MLHCIMPN_00278 2.54e-50 yfhS - - - - - - -
MLHCIMPN_00279 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_00280 7.33e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MLHCIMPN_00281 1.4e-49 ygaB - - S - - - YgaB-like protein
MLHCIMPN_00282 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MLHCIMPN_00283 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MLHCIMPN_00284 5.27e-239 ygaE - - S - - - Membrane
MLHCIMPN_00285 2.79e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MLHCIMPN_00286 3.28e-110 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MLHCIMPN_00287 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MLHCIMPN_00288 4.67e-75 ygzB - - S - - - UPF0295 protein
MLHCIMPN_00289 1.12e-212 ygxA - - S - - - Nucleotidyltransferase-like
MLHCIMPN_00292 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MLHCIMPN_00293 3.93e-309 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MLHCIMPN_00294 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
MLHCIMPN_00295 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
MLHCIMPN_00296 1.84e-236 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MLHCIMPN_00297 9.42e-83 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
MLHCIMPN_00298 1.78e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MLHCIMPN_00299 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHCIMPN_00300 5.93e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MLHCIMPN_00301 2.05e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MLHCIMPN_00302 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHCIMPN_00303 1.2e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHCIMPN_00304 1.72e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHCIMPN_00305 2.85e-169 yfmS - - NT - - - chemotaxis protein
MLHCIMPN_00306 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHCIMPN_00307 8.39e-313 yfnA - - E ko:K03294 - ko00000 amino acid
MLHCIMPN_00308 1.56e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_00309 1.99e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MLHCIMPN_00310 7.24e-285 yfnE - - S - - - Glycosyltransferase like family 2
MLHCIMPN_00311 1.9e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MLHCIMPN_00312 3.93e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MLHCIMPN_00313 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MLHCIMPN_00314 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MLHCIMPN_00316 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MLHCIMPN_00317 2.28e-250 yetN - - S - - - Protein of unknown function (DUF3900)
MLHCIMPN_00318 2.19e-267 yetM - - CH - - - FAD binding domain
MLHCIMPN_00319 3.45e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_00320 1.8e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MLHCIMPN_00321 1.82e-73 - - - H - - - riboflavin kinase activity
MLHCIMPN_00322 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
MLHCIMPN_00323 6.28e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHCIMPN_00324 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHCIMPN_00325 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MLHCIMPN_00326 8.99e-157 yetF - - S - - - membrane
MLHCIMPN_00327 5.92e-05 - - - - - - - -
MLHCIMPN_00328 1.39e-123 yesJ - - K - - - Acetyltransferase (GNAT) family
MLHCIMPN_00329 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MLHCIMPN_00330 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
MLHCIMPN_00331 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MLHCIMPN_00332 2.21e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MLHCIMPN_00334 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
MLHCIMPN_00335 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
MLHCIMPN_00336 2.38e-101 - - - S - - - Protein of unknown function, DUF600
MLHCIMPN_00337 7.72e-68 - - - S - - - Protein of unknown function, DUF600
MLHCIMPN_00338 2.57e-60 - - - S - - - Protein of unknown function, DUF600
MLHCIMPN_00339 8.27e-67 - - - S - - - Protein of unknown function, DUF600
MLHCIMPN_00340 2.31e-80 - - - S - - - Protein of unknown function, DUF600
MLHCIMPN_00341 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MLHCIMPN_00342 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLHCIMPN_00343 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MLHCIMPN_00344 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLHCIMPN_00345 7.33e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLHCIMPN_00346 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLHCIMPN_00347 3.16e-197 yerO - - K - - - Transcriptional regulator
MLHCIMPN_00348 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHCIMPN_00349 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLHCIMPN_00350 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLHCIMPN_00351 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHCIMPN_00352 1.44e-158 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MLHCIMPN_00353 2.19e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MLHCIMPN_00354 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MLHCIMPN_00355 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLHCIMPN_00356 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MLHCIMPN_00357 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLHCIMPN_00358 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MLHCIMPN_00359 2.03e-67 yerC - - S - - - protein conserved in bacteria
MLHCIMPN_00360 4.95e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MLHCIMPN_00361 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MLHCIMPN_00362 1.03e-34 - - - S - - - Protein of unknown function (DUF2892)
MLHCIMPN_00363 8.44e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MLHCIMPN_00364 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MLHCIMPN_00365 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLHCIMPN_00366 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MLHCIMPN_00367 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLHCIMPN_00368 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHCIMPN_00369 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHCIMPN_00370 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLHCIMPN_00371 2.79e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MLHCIMPN_00372 2.59e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLHCIMPN_00373 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLHCIMPN_00374 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLHCIMPN_00375 2.21e-38 yebG - - S - - - NETI protein
MLHCIMPN_00376 2.66e-120 yebE - - S - - - UPF0316 protein
MLHCIMPN_00378 2.16e-168 yebC - - M - - - Membrane
MLHCIMPN_00379 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MLHCIMPN_00380 0.0 - - - S - - - Domain of unknown function (DUF4179)
MLHCIMPN_00381 1.9e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00382 5.95e-102 - - - - - - - -
MLHCIMPN_00383 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MLHCIMPN_00384 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MLHCIMPN_00385 3.13e-274 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLHCIMPN_00386 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MLHCIMPN_00387 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_00388 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MLHCIMPN_00389 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
MLHCIMPN_00391 7.08e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MLHCIMPN_00392 1.6e-82 ydjM - - M - - - Lytic transglycolase
MLHCIMPN_00393 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MLHCIMPN_00394 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00395 9.73e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
MLHCIMPN_00396 0.0 oatA - - I - - - Acyltransferase family
MLHCIMPN_00397 3.22e-223 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MLHCIMPN_00398 4.16e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MLHCIMPN_00399 3.49e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLHCIMPN_00400 9.58e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MLHCIMPN_00401 3.61e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
MLHCIMPN_00402 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MLHCIMPN_00403 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MLHCIMPN_00404 1.69e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MLHCIMPN_00405 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MLHCIMPN_00406 2.41e-98 yfiJ - - T - - - helix_turn_helix, Lux Regulon
MLHCIMPN_00407 0.0 pbpX - - V - - - Beta-lactamase
MLHCIMPN_00408 2.24e-127 - - - S - - - Putative sensor
MLHCIMPN_00409 0.0 yvfT - - T - - - helix_turn_helix, Lux Regulon
MLHCIMPN_00410 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLHCIMPN_00411 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLHCIMPN_00412 2.27e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHCIMPN_00413 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MLHCIMPN_00414 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLHCIMPN_00415 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLHCIMPN_00416 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLHCIMPN_00417 2.84e-115 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLHCIMPN_00418 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MLHCIMPN_00419 6.49e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLHCIMPN_00420 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLHCIMPN_00421 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MLHCIMPN_00422 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MLHCIMPN_00423 4e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLHCIMPN_00435 3.31e-281 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MLHCIMPN_00436 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHCIMPN_00437 7.74e-231 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
MLHCIMPN_00438 3.13e-253 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MLHCIMPN_00439 2.62e-286 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MLHCIMPN_00440 1.08e-222 ybaS - - S - - - Na -dependent transporter
MLHCIMPN_00441 1.35e-143 ybbA - - S ko:K07017 - ko00000 Putative esterase
MLHCIMPN_00442 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_00443 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_00444 1.21e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MLHCIMPN_00445 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MLHCIMPN_00446 2.61e-299 ybbC - - S - - - protein conserved in bacteria
MLHCIMPN_00447 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MLHCIMPN_00448 2.56e-308 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MLHCIMPN_00449 5.86e-310 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_00450 3.84e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLHCIMPN_00451 7.13e-110 ybbJ - - J - - - acetyltransferase
MLHCIMPN_00452 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
MLHCIMPN_00458 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00459 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLHCIMPN_00460 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLHCIMPN_00461 7.18e-291 ybbR - - S - - - protein conserved in bacteria
MLHCIMPN_00462 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLHCIMPN_00463 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLHCIMPN_00464 2.14e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLHCIMPN_00465 1.42e-138 - - - S - - - ABC-2 family transporter protein
MLHCIMPN_00466 8.72e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_00467 2.32e-235 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
MLHCIMPN_00468 6.57e-176 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_00469 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_00470 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLHCIMPN_00471 1.03e-206 dkgB - - S - - - Aldo/keto reductase family
MLHCIMPN_00472 6.05e-135 yxaC - - M - - - effector of murein hydrolase
MLHCIMPN_00473 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MLHCIMPN_00474 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_00476 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_00477 1.07e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLHCIMPN_00478 2.38e-253 - - - T - - - COG4585 Signal transduction histidine kinase
MLHCIMPN_00479 2.04e-141 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MLHCIMPN_00480 6.21e-214 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MLHCIMPN_00481 3.18e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MLHCIMPN_00482 1.32e-252 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_00483 2.34e-35 - - - - - - - -
MLHCIMPN_00484 6.08e-102 - - - S - - - Domain of unknown function (DUF4879)
MLHCIMPN_00485 1.01e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MLHCIMPN_00486 4.16e-143 yqeB - - - - - - -
MLHCIMPN_00487 7.84e-55 ybyB - - - - - - -
MLHCIMPN_00488 0.0 ybeC - - E - - - amino acid
MLHCIMPN_00489 5.3e-62 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLHCIMPN_00491 6.28e-23 - - - S - - - Protein of unknown function (DUF2651)
MLHCIMPN_00492 8.18e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MLHCIMPN_00493 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MLHCIMPN_00494 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
MLHCIMPN_00495 1.66e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MLHCIMPN_00497 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MLHCIMPN_00498 1.14e-25 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
MLHCIMPN_00499 8.96e-67 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
MLHCIMPN_00501 4.73e-176 draG - - O - - - ADP-ribosylglycohydrolase
MLHCIMPN_00502 2.1e-71 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MLHCIMPN_00503 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHCIMPN_00504 8.67e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MLHCIMPN_00505 1.87e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLHCIMPN_00506 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLHCIMPN_00507 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
MLHCIMPN_00508 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLHCIMPN_00509 8.67e-55 ybfN - - - - - - -
MLHCIMPN_00510 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MLHCIMPN_00511 1.17e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHCIMPN_00512 8.33e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLHCIMPN_00513 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLHCIMPN_00514 1.69e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MLHCIMPN_00515 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MLHCIMPN_00516 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLHCIMPN_00517 1.26e-278 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_00518 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MLHCIMPN_00519 2.46e-08 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MLHCIMPN_00520 4.85e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MLHCIMPN_00521 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHCIMPN_00522 9.49e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MLHCIMPN_00523 2.06e-233 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLHCIMPN_00524 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
MLHCIMPN_00525 2.56e-72 ydfQ - - CO - - - Thioredoxin
MLHCIMPN_00526 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
MLHCIMPN_00527 1.44e-99 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MLHCIMPN_00528 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MLHCIMPN_00529 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLHCIMPN_00530 4.24e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLHCIMPN_00531 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLHCIMPN_00532 1.92e-263 ycbU - - E - - - Selenocysteine lyase
MLHCIMPN_00533 1.68e-311 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MLHCIMPN_00534 1.04e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MLHCIMPN_00535 1.8e-250 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLHCIMPN_00536 3.29e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLHCIMPN_00537 9.7e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
MLHCIMPN_00538 6.12e-69 yccK - - C - - - Aldo keto reductase
MLHCIMPN_00539 9e-129 yccK - - C - - - Aldo keto reductase
MLHCIMPN_00540 6.27e-224 ycdA - - S - - - Domain of unknown function (DUF5105)
MLHCIMPN_00541 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00542 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00543 1.79e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MLHCIMPN_00544 5.77e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MLHCIMPN_00545 1.23e-178 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MLHCIMPN_00546 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLHCIMPN_00547 3.64e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MLHCIMPN_00548 5.69e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLHCIMPN_00549 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLHCIMPN_00550 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_00551 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MLHCIMPN_00552 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MLHCIMPN_00553 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MLHCIMPN_00554 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MLHCIMPN_00555 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MLHCIMPN_00556 4.74e-246 yceH - - P - - - Belongs to the TelA family
MLHCIMPN_00557 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MLHCIMPN_00558 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MLHCIMPN_00559 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MLHCIMPN_00560 2.85e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MLHCIMPN_00561 4.59e-270 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MLHCIMPN_00562 8.03e-294 ycgA - - S - - - Membrane
MLHCIMPN_00563 4.41e-106 ycgB - - - - - - -
MLHCIMPN_00564 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MLHCIMPN_00565 5.7e-32 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MLHCIMPN_00566 6.6e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MLHCIMPN_00567 0.0 mdr - - EGP - - - the major facilitator superfamily
MLHCIMPN_00568 2.82e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_00569 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MLHCIMPN_00570 4.19e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MLHCIMPN_00571 1.15e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_00572 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MLHCIMPN_00573 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLHCIMPN_00574 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
MLHCIMPN_00575 2.44e-141 tmrB - - S - - - AAA domain
MLHCIMPN_00576 5.46e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MLHCIMPN_00577 2.75e-287 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_00578 1.01e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLHCIMPN_00579 3.29e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MLHCIMPN_00580 8.94e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MLHCIMPN_00581 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MLHCIMPN_00582 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLHCIMPN_00583 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHCIMPN_00584 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MLHCIMPN_00585 3.33e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MLHCIMPN_00586 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MLHCIMPN_00587 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MLHCIMPN_00588 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLHCIMPN_00589 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHCIMPN_00590 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
MLHCIMPN_00591 4.05e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MLHCIMPN_00592 1.73e-290 yciC - - S - - - GTPases (G3E family)
MLHCIMPN_00593 7.17e-281 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLHCIMPN_00594 2.2e-95 yckC - - S - - - membrane
MLHCIMPN_00595 9.5e-68 - - - S - - - Protein of unknown function (DUF2680)
MLHCIMPN_00596 1.37e-43 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHCIMPN_00597 6.79e-91 nin - - S - - - Competence protein J (ComJ)
MLHCIMPN_00598 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
MLHCIMPN_00599 1.22e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MLHCIMPN_00600 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MLHCIMPN_00601 4.1e-84 hxlR - - K - - - transcriptional
MLHCIMPN_00603 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_00604 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLHCIMPN_00605 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MLHCIMPN_00606 5.72e-316 - - - E - - - Aminotransferase class I and II
MLHCIMPN_00607 1.3e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MLHCIMPN_00608 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
MLHCIMPN_00609 3.24e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLHCIMPN_00610 3.53e-153 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLHCIMPN_00611 8.63e-121 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MLHCIMPN_00612 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MLHCIMPN_00613 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLHCIMPN_00614 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLHCIMPN_00615 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MLHCIMPN_00616 6.81e-100 yclD - - - - - - -
MLHCIMPN_00617 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MLHCIMPN_00618 0.0 yclG - - M - - - Pectate lyase superfamily protein
MLHCIMPN_00620 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MLHCIMPN_00621 2.82e-300 gerKC - - S ko:K06297 - ko00000 spore germination
MLHCIMPN_00622 1.86e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MLHCIMPN_00623 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_00624 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHCIMPN_00625 5.21e-182 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLHCIMPN_00626 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLHCIMPN_00627 2.28e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_00628 2.3e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MLHCIMPN_00629 0.0 yxeQ - - S - - - MmgE/PrpD family
MLHCIMPN_00630 1.62e-158 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MLHCIMPN_00631 6.53e-309 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MLHCIMPN_00632 2.6e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_00633 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
MLHCIMPN_00634 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLHCIMPN_00636 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLHCIMPN_00637 3.85e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_00638 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_00639 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_00640 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MLHCIMPN_00641 3.99e-313 ycnB - - EGP - - - the major facilitator superfamily
MLHCIMPN_00642 4.47e-197 ycnC - - K - - - Transcriptional regulator
MLHCIMPN_00643 1.97e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
MLHCIMPN_00644 8.02e-59 ycnE - - S - - - Monooxygenase
MLHCIMPN_00645 2.76e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHCIMPN_00646 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHCIMPN_00647 2.17e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHCIMPN_00648 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHCIMPN_00649 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MLHCIMPN_00650 4.85e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_00651 2.05e-131 ycnI - - S - - - protein conserved in bacteria
MLHCIMPN_00652 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MLHCIMPN_00653 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLHCIMPN_00654 1.59e-71 - - - - - - - -
MLHCIMPN_00655 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLHCIMPN_00656 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLHCIMPN_00657 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLHCIMPN_00658 1.38e-85 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MLHCIMPN_00660 1.1e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLHCIMPN_00661 8.34e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MLHCIMPN_00662 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLHCIMPN_00663 1.4e-191 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MLHCIMPN_00664 2.7e-174 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MLHCIMPN_00665 1.03e-241 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MLHCIMPN_00666 2.69e-166 kipR - - K - - - Transcriptional regulator
MLHCIMPN_00667 2.23e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MLHCIMPN_00669 5.95e-75 yczJ - - S - - - biosynthesis
MLHCIMPN_00670 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MLHCIMPN_00671 2.57e-221 ycsN - - S - - - Oxidoreductase
MLHCIMPN_00672 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MLHCIMPN_00673 0.0 ydaB - - IQ - - - acyl-CoA ligase
MLHCIMPN_00674 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_00675 7.9e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MLHCIMPN_00676 1.3e-145 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLHCIMPN_00677 1.83e-101 ydaG - - S - - - general stress protein
MLHCIMPN_00678 2.54e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLHCIMPN_00679 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MLHCIMPN_00680 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MLHCIMPN_00681 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLHCIMPN_00682 1.34e-256 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLHCIMPN_00683 2.67e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MLHCIMPN_00684 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MLHCIMPN_00685 2.16e-301 ydaM - - M - - - Glycosyl transferase family group 2
MLHCIMPN_00686 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MLHCIMPN_00687 0.0 ydaO - - E - - - amino acid
MLHCIMPN_00688 1.04e-74 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MLHCIMPN_00689 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MLHCIMPN_00690 2.27e-101 - - - - - - - -
MLHCIMPN_00692 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MLHCIMPN_00694 2.69e-12 - - - - - - - -
MLHCIMPN_00696 2.53e-114 - - - - - - - -
MLHCIMPN_00697 1.65e-127 - - - - - - - -
MLHCIMPN_00698 7.45e-54 - - - - - - - -
MLHCIMPN_00699 1.08e-287 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MLHCIMPN_00701 1.95e-45 ydaT - - - - - - -
MLHCIMPN_00702 5.32e-94 yvaD - - S - - - Family of unknown function (DUF5360)
MLHCIMPN_00703 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MLHCIMPN_00704 1.09e-181 ydbA - - P - - - EcsC protein family
MLHCIMPN_00705 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
MLHCIMPN_00706 2.65e-78 ydbB - - G - - - Cupin domain
MLHCIMPN_00707 1.01e-79 ydbC - - S - - - Domain of unknown function (DUF4937
MLHCIMPN_00708 1.92e-198 ydbD - - P ko:K07217 - ko00000 Catalase
MLHCIMPN_00709 2.58e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLHCIMPN_00710 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLHCIMPN_00711 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MLHCIMPN_00712 1.59e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHCIMPN_00713 8.61e-231 ydbI - - S - - - AI-2E family transporter
MLHCIMPN_00714 3.37e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_00715 3.47e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHCIMPN_00716 5.4e-69 ydbL - - - - - - -
MLHCIMPN_00717 2.15e-261 ydbM - - I - - - acyl-CoA dehydrogenase
MLHCIMPN_00718 1.13e-15 - - - S - - - Fur-regulated basic protein B
MLHCIMPN_00719 9.35e-14 - - - S - - - Fur-regulated basic protein A
MLHCIMPN_00720 6.66e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHCIMPN_00721 2.25e-74 ydbP - - CO - - - Thioredoxin
MLHCIMPN_00722 2.52e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MLHCIMPN_00723 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLHCIMPN_00724 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLHCIMPN_00725 1.96e-108 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MLHCIMPN_00726 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MLHCIMPN_00727 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MLHCIMPN_00728 1.09e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLHCIMPN_00729 1.29e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MLHCIMPN_00730 3.83e-277 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLHCIMPN_00731 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLHCIMPN_00732 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MLHCIMPN_00733 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MLHCIMPN_00734 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MLHCIMPN_00735 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLHCIMPN_00736 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MLHCIMPN_00737 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MLHCIMPN_00738 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLHCIMPN_00739 1.61e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_00740 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MLHCIMPN_00741 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MLHCIMPN_00742 1.78e-21 - - - - - - - -
MLHCIMPN_00743 2.88e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MLHCIMPN_00752 9.77e-150 - - - S - - - ATPase (AAA superfamily
MLHCIMPN_00754 3.81e-56 - - - - - - - -
MLHCIMPN_00755 3.49e-175 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHCIMPN_00757 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
MLHCIMPN_00758 1.04e-65 ohrR - - K - - - Transcriptional regulator
MLHCIMPN_00759 1.41e-93 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
MLHCIMPN_00760 2.13e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
MLHCIMPN_00761 1.59e-85 - - - S - - - YjbR
MLHCIMPN_00762 4.07e-97 ywnA - - K - - - Transcriptional regulator
MLHCIMPN_00763 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MLHCIMPN_00764 1.97e-241 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MLHCIMPN_00765 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MLHCIMPN_00766 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
MLHCIMPN_00767 1.53e-52 yrkD - - S - - - protein conserved in bacteria
MLHCIMPN_00768 9.32e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
MLHCIMPN_00769 1.42e-76 - - - P - - - Rhodanese Homology Domain
MLHCIMPN_00770 3.64e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
MLHCIMPN_00771 1.6e-251 yrkH - - P - - - Rhodanese Homology Domain
MLHCIMPN_00772 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
MLHCIMPN_00773 1.25e-166 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
MLHCIMPN_00774 8.33e-156 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLHCIMPN_00775 1.48e-133 - - - S - - - Protein of unknown function (DUF2812)
MLHCIMPN_00776 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
MLHCIMPN_00777 1.45e-233 - - - S - - - Patatin-like phospholipase
MLHCIMPN_00778 6.08e-102 - - - S - - - DinB superfamily
MLHCIMPN_00779 4.11e-82 - - - G - - - Cupin domain
MLHCIMPN_00781 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MLHCIMPN_00782 5.11e-214 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MLHCIMPN_00783 9.68e-251 trkA - - P ko:K07222 - ko00000 Oxidoreductase
MLHCIMPN_00785 1.63e-131 yrkC - - G - - - Cupin domain
MLHCIMPN_00786 1.88e-98 ykkA - - S - - - Protein of unknown function (DUF664)
MLHCIMPN_00787 2.58e-37 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
MLHCIMPN_00788 3.29e-36 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
MLHCIMPN_00790 2.9e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MLHCIMPN_00791 1.19e-68 ydeH - - - - - - -
MLHCIMPN_00792 2.07e-212 - - - S - - - Sodium Bile acid symporter family
MLHCIMPN_00793 9.05e-258 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MLHCIMPN_00794 4.93e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MLHCIMPN_00795 5.68e-281 nhaC_1 - - C - - - antiporter
MLHCIMPN_00796 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MLHCIMPN_00797 3.59e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_00799 3.57e-249 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
MLHCIMPN_00800 1.2e-132 ydeS - - K - - - Transcriptional regulator
MLHCIMPN_00801 2.5e-200 ydeK - - EG - - - -transporter
MLHCIMPN_00802 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHCIMPN_00803 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
MLHCIMPN_00804 1.19e-33 yraE - - - ko:K06440 - ko00000 -
MLHCIMPN_00805 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLHCIMPN_00806 3.35e-84 yraF - - M - - - Spore coat protein
MLHCIMPN_00807 1.71e-49 yraG - - - ko:K06440 - ko00000 -
MLHCIMPN_00808 1.91e-272 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_00809 3.28e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_00810 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MLHCIMPN_00811 3.41e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
MLHCIMPN_00812 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MLHCIMPN_00813 7.5e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
MLHCIMPN_00814 4.59e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_00815 1.08e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
MLHCIMPN_00816 1.59e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MLHCIMPN_00817 3.76e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLHCIMPN_00818 7.49e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
MLHCIMPN_00819 3.66e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MLHCIMPN_00820 5.09e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MLHCIMPN_00821 6.89e-192 bltR - - K - - - helix_turn_helix, mercury resistance
MLHCIMPN_00822 2.1e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLHCIMPN_00823 1.35e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MLHCIMPN_00824 1.34e-187 - - - Q - - - ubiE/COQ5 methyltransferase family
MLHCIMPN_00825 9.74e-209 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
MLHCIMPN_00826 2.67e-153 ydhC - - K - - - FCD
MLHCIMPN_00827 1.94e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLHCIMPN_00830 0.0 pbpE - - V - - - Beta-lactamase
MLHCIMPN_00832 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
MLHCIMPN_00833 1.29e-246 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MLHCIMPN_00834 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MLHCIMPN_00835 1.55e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
MLHCIMPN_00836 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MLHCIMPN_00837 1.73e-64 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MLHCIMPN_00838 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLHCIMPN_00839 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
MLHCIMPN_00840 0.0 ybeC - - E - - - amino acid
MLHCIMPN_00841 1.04e-212 ydhU - - P ko:K07217 - ko00000 Catalase
MLHCIMPN_00842 1.7e-111 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MLHCIMPN_00843 1.64e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MLHCIMPN_00844 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLHCIMPN_00847 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00848 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00849 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_00850 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLHCIMPN_00851 1.9e-279 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLHCIMPN_00852 5.31e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MLHCIMPN_00853 1.38e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MLHCIMPN_00854 1.95e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHCIMPN_00855 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLHCIMPN_00856 2.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_00857 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MLHCIMPN_00858 2.58e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MLHCIMPN_00859 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHCIMPN_00861 2.91e-238 yueF - - S - - - transporter activity
MLHCIMPN_00863 9.19e-76 - - - S - - - YolD-like protein
MLHCIMPN_00864 7.74e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLHCIMPN_00865 4.67e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MLHCIMPN_00866 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MLHCIMPN_00867 1.76e-224 yqkA - - K - - - GrpB protein
MLHCIMPN_00868 2.2e-79 yqkB - - S - - - Belongs to the HesB IscA family
MLHCIMPN_00869 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
MLHCIMPN_00870 2.27e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MLHCIMPN_00871 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
MLHCIMPN_00872 1.08e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MLHCIMPN_00873 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
MLHCIMPN_00874 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MLHCIMPN_00875 6.89e-279 yqxK - - L - - - DNA helicase
MLHCIMPN_00876 1.34e-74 ansR - - K - - - Transcriptional regulator
MLHCIMPN_00877 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MLHCIMPN_00878 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MLHCIMPN_00879 2.4e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MLHCIMPN_00880 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MLHCIMPN_00881 3.39e-31 - - - - - - - -
MLHCIMPN_00882 7.07e-40 yqkK - - - - - - -
MLHCIMPN_00883 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLHCIMPN_00884 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MLHCIMPN_00885 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
MLHCIMPN_00886 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MLHCIMPN_00887 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLHCIMPN_00888 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLHCIMPN_00889 1.43e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLHCIMPN_00890 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MLHCIMPN_00891 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLHCIMPN_00892 7.94e-173 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_00893 3.86e-142 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MLHCIMPN_00894 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MLHCIMPN_00895 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MLHCIMPN_00896 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MLHCIMPN_00897 5.32e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
MLHCIMPN_00898 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MLHCIMPN_00899 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLHCIMPN_00900 2.11e-197 ypuA - - S - - - Secreted protein
MLHCIMPN_00901 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLHCIMPN_00902 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
MLHCIMPN_00903 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLHCIMPN_00904 4.92e-71 ypuD - - - - - - -
MLHCIMPN_00905 1.08e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLHCIMPN_00906 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MLHCIMPN_00907 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLHCIMPN_00908 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLHCIMPN_00909 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHCIMPN_00910 4.51e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MLHCIMPN_00912 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLHCIMPN_00913 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLHCIMPN_00914 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
MLHCIMPN_00915 1.62e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MLHCIMPN_00916 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MLHCIMPN_00917 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MLHCIMPN_00918 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLHCIMPN_00919 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLHCIMPN_00920 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MLHCIMPN_00921 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLHCIMPN_00922 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_00923 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_00924 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_00925 5.62e-254 rsiX - - - - - - -
MLHCIMPN_00926 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHCIMPN_00927 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLHCIMPN_00928 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MLHCIMPN_00929 7.41e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MLHCIMPN_00930 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLHCIMPN_00931 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MLHCIMPN_00932 1.5e-132 ypbE - - M - - - Lysin motif
MLHCIMPN_00933 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
MLHCIMPN_00934 1.15e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MLHCIMPN_00935 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLHCIMPN_00936 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLHCIMPN_00937 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MLHCIMPN_00938 7.48e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MLHCIMPN_00939 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MLHCIMPN_00940 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
MLHCIMPN_00941 3.83e-76 ypfA - - M - - - Flagellar protein YcgR
MLHCIMPN_00942 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
MLHCIMPN_00943 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MLHCIMPN_00944 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MLHCIMPN_00945 1.98e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLHCIMPN_00946 1.87e-12 - - - S - - - YpzI-like protein
MLHCIMPN_00947 6.19e-136 yphA - - - - - - -
MLHCIMPN_00948 9.53e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MLHCIMPN_00949 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MLHCIMPN_00950 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
MLHCIMPN_00951 3.4e-173 yphF - - - - - - -
MLHCIMPN_00952 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLHCIMPN_00953 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLHCIMPN_00954 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MLHCIMPN_00955 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLHCIMPN_00956 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLHCIMPN_00957 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLHCIMPN_00958 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLHCIMPN_00959 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLHCIMPN_00960 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MLHCIMPN_00961 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLHCIMPN_00962 7.47e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLHCIMPN_00963 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLHCIMPN_00964 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLHCIMPN_00965 2.37e-211 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLHCIMPN_00966 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MLHCIMPN_00967 2.05e-147 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MLHCIMPN_00968 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLHCIMPN_00969 7.71e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLHCIMPN_00970 7.15e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLHCIMPN_00971 1.24e-260 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MLHCIMPN_00972 3.46e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLHCIMPN_00973 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
MLHCIMPN_00974 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
MLHCIMPN_00975 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
MLHCIMPN_00976 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MLHCIMPN_00977 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MLHCIMPN_00978 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MLHCIMPN_00979 7.24e-134 ypjA - - S - - - membrane
MLHCIMPN_00980 2.05e-182 ypjB - - S - - - sporulation protein
MLHCIMPN_00981 1.97e-55 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MLHCIMPN_00982 5.09e-212 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MLHCIMPN_00983 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_00984 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MLHCIMPN_00985 3.98e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLHCIMPN_00986 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MLHCIMPN_00987 7.44e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MLHCIMPN_00988 2.98e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLHCIMPN_00989 3.99e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLHCIMPN_00990 7.73e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLHCIMPN_00991 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLHCIMPN_00992 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLHCIMPN_00993 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLHCIMPN_00994 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MLHCIMPN_00995 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MLHCIMPN_00996 2.27e-103 ypmB - - S - - - protein conserved in bacteria
MLHCIMPN_00997 1.46e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MLHCIMPN_00998 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MLHCIMPN_00999 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MLHCIMPN_01000 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLHCIMPN_01001 1.04e-118 ypoC - - - - - - -
MLHCIMPN_01002 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLHCIMPN_01003 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLHCIMPN_01004 4.72e-238 yppC - - S - - - Protein of unknown function (DUF2515)
MLHCIMPN_01005 0.000542 - - - - ko:K06430 - ko00000 -
MLHCIMPN_01009 1.85e-74 yppG - - S - - - YppG-like protein
MLHCIMPN_01010 1.85e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHCIMPN_01011 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MLHCIMPN_01012 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLHCIMPN_01013 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MLHCIMPN_01015 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
MLHCIMPN_01016 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
MLHCIMPN_01017 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLHCIMPN_01018 5.46e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MLHCIMPN_01019 6.91e-31 - - - S - - - YpzG-like protein
MLHCIMPN_01021 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MLHCIMPN_01022 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLHCIMPN_01023 4.72e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLHCIMPN_01024 2.4e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
MLHCIMPN_01025 1.05e-05 - - - - - - - -
MLHCIMPN_01026 3.79e-131 yrdC - - Q - - - Isochorismatase family
MLHCIMPN_01027 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
MLHCIMPN_01028 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
MLHCIMPN_01029 2.52e-136 - - - J - - - Acetyltransferase (GNAT) domain
MLHCIMPN_01030 5.13e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MLHCIMPN_01031 2.09e-116 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MLHCIMPN_01032 0.0 ypbR - - S - - - Dynamin family
MLHCIMPN_01033 8.23e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
MLHCIMPN_01034 2.44e-10 - - - - - - - -
MLHCIMPN_01035 3.33e-210 ypcP - - L - - - 5'3' exonuclease
MLHCIMPN_01037 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MLHCIMPN_01038 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLHCIMPN_01039 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MLHCIMPN_01040 6.59e-40 ypeQ - - S - - - Zinc-finger
MLHCIMPN_01041 9.27e-49 - - - S - - - Protein of unknown function (DUF2564)
MLHCIMPN_01042 5.19e-17 degR - - - - - - -
MLHCIMPN_01043 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MLHCIMPN_01044 1.49e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLHCIMPN_01045 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLHCIMPN_01046 9.26e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MLHCIMPN_01047 7.66e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MLHCIMPN_01048 5.44e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MLHCIMPN_01049 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MLHCIMPN_01050 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
MLHCIMPN_01051 8.22e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MLHCIMPN_01052 6.48e-148 ypjP - - S - - - YpjP-like protein
MLHCIMPN_01053 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLHCIMPN_01054 6.07e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLHCIMPN_01055 1.35e-147 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLHCIMPN_01056 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MLHCIMPN_01057 5.8e-224 yplP - - K - - - Transcriptional regulator
MLHCIMPN_01058 1.42e-307 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLHCIMPN_01059 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
MLHCIMPN_01060 2.43e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLHCIMPN_01061 6.09e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MLHCIMPN_01062 5.59e-126 ypmS - - S - - - protein conserved in bacteria
MLHCIMPN_01063 3.35e-89 ypoP - - K - - - transcriptional
MLHCIMPN_01064 2.82e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLHCIMPN_01065 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MLHCIMPN_01066 3.43e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLHCIMPN_01067 0.0 yokA - - L - - - Recombinase
MLHCIMPN_01068 4.29e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MLHCIMPN_01069 4.26e-109 - - - G - - - SMI1-KNR4 cell-wall
MLHCIMPN_01070 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHCIMPN_01071 2.6e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MLHCIMPN_01073 3.41e-216 - - - S - - - amine dehydrogenase activity
MLHCIMPN_01075 6.38e-259 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLHCIMPN_01076 1.24e-50 yoqH - - M - - - LysM domain
MLHCIMPN_01081 4.14e-94 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLHCIMPN_01082 6.87e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MLHCIMPN_01083 1.88e-223 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MLHCIMPN_01084 3.12e-90 cgeA - - - ko:K06319 - ko00000 -
MLHCIMPN_01085 1.64e-62 cgeC - - - ko:K06321 - ko00000 -
MLHCIMPN_01086 8.84e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MLHCIMPN_01087 5.71e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MLHCIMPN_01089 1.19e-83 - - - L - - - Bacterial transcription activator, effector binding domain
MLHCIMPN_01090 1.69e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHCIMPN_01091 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLHCIMPN_01092 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLHCIMPN_01093 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MLHCIMPN_01094 9.87e-204 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MLHCIMPN_01095 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MLHCIMPN_01096 8.13e-62 yokU - - S - - - YokU-like protein, putative antitoxin
MLHCIMPN_01097 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
MLHCIMPN_01098 1.9e-161 yodN - - - - - - -
MLHCIMPN_01100 9.77e-34 yozD - - S - - - YozD-like protein
MLHCIMPN_01101 5.88e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MLHCIMPN_01102 1.16e-72 yodL - - S - - - YodL-like
MLHCIMPN_01104 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MLHCIMPN_01105 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MLHCIMPN_01106 6.87e-50 yodI - - - - - - -
MLHCIMPN_01107 6.12e-166 yodH - - Q - - - Methyltransferase
MLHCIMPN_01108 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MLHCIMPN_01109 5.86e-168 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01110 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHCIMPN_01111 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MLHCIMPN_01112 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHCIMPN_01113 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
MLHCIMPN_01114 1.09e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLHCIMPN_01115 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MLHCIMPN_01116 1.35e-138 yodC - - C - - - nitroreductase
MLHCIMPN_01117 1.2e-74 yodB - - K - - - transcriptional
MLHCIMPN_01118 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
MLHCIMPN_01119 1.5e-88 iolK - - S - - - tautomerase
MLHCIMPN_01121 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MLHCIMPN_01122 4.91e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MLHCIMPN_01123 5.2e-31 - - - - - - - -
MLHCIMPN_01124 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
MLHCIMPN_01125 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MLHCIMPN_01126 1.68e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHCIMPN_01127 2.39e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MLHCIMPN_01129 4.5e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLHCIMPN_01130 1.13e-276 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MLHCIMPN_01131 3.47e-287 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLHCIMPN_01132 6.26e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLHCIMPN_01133 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MLHCIMPN_01134 0.0 yojO - - P - - - Von Willebrand factor
MLHCIMPN_01135 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLHCIMPN_01136 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLHCIMPN_01137 1.98e-179 - - - S - - - Metallo-beta-lactamase superfamily
MLHCIMPN_01138 2.82e-214 yocS - - S ko:K03453 - ko00000 -transporter
MLHCIMPN_01139 4.17e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLHCIMPN_01140 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MLHCIMPN_01141 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MLHCIMPN_01142 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLHCIMPN_01143 1.11e-41 yozC - - - - - - -
MLHCIMPN_01145 5.32e-75 yozO - - S - - - Bacterial PH domain
MLHCIMPN_01146 6.36e-50 yocN - - - - - - -
MLHCIMPN_01147 1.87e-57 yozN - - - - - - -
MLHCIMPN_01148 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MLHCIMPN_01149 4.98e-13 yocN - - - - - - -
MLHCIMPN_01150 2.71e-13 yocL - - - - - - -
MLHCIMPN_01151 4.5e-79 yocK - - T - - - general stress protein
MLHCIMPN_01153 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHCIMPN_01154 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLHCIMPN_01155 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
MLHCIMPN_01157 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MLHCIMPN_01158 2.27e-123 yocC - - - - - - -
MLHCIMPN_01159 4.8e-179 - - - J - - - Protein required for attachment to host cells
MLHCIMPN_01160 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
MLHCIMPN_01161 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLHCIMPN_01162 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MLHCIMPN_01163 1.57e-118 yobW - - - - - - -
MLHCIMPN_01164 1.98e-174 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLHCIMPN_01165 8.84e-121 yobS - - K - - - Transcriptional regulator
MLHCIMPN_01166 9.78e-169 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MLHCIMPN_01167 1.05e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MLHCIMPN_01168 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLHCIMPN_01169 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
MLHCIMPN_01170 5.5e-56 - - - - - - - -
MLHCIMPN_01171 1.63e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_01173 2.99e-22 yoaF - - - - - - -
MLHCIMPN_01174 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHCIMPN_01175 4.74e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHCIMPN_01176 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MLHCIMPN_01177 1.1e-261 yoaB - - EGP - - - the major facilitator superfamily
MLHCIMPN_01178 2.12e-176 yoxB - - - - - - -
MLHCIMPN_01179 3.03e-50 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLHCIMPN_01180 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_01181 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLHCIMPN_01182 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHCIMPN_01183 2.82e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLHCIMPN_01184 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01185 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MLHCIMPN_01186 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLHCIMPN_01187 1.77e-239 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLHCIMPN_01188 2.6e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01189 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLHCIMPN_01190 3.29e-67 - - - K - - - Helix-turn-helix domain
MLHCIMPN_01191 1.95e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
MLHCIMPN_01192 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MLHCIMPN_01193 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
MLHCIMPN_01194 3.97e-125 - - - L - - - Integrase
MLHCIMPN_01196 2.13e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MLHCIMPN_01197 7.44e-312 yoeA - - V - - - MATE efflux family protein
MLHCIMPN_01198 1.16e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MLHCIMPN_01199 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MLHCIMPN_01221 1.82e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MLHCIMPN_01222 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
MLHCIMPN_01223 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MLHCIMPN_01224 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLHCIMPN_01225 2.52e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLHCIMPN_01226 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLHCIMPN_01227 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLHCIMPN_01228 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLHCIMPN_01229 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MLHCIMPN_01230 1.06e-234 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLHCIMPN_01231 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MLHCIMPN_01232 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MLHCIMPN_01233 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MLHCIMPN_01234 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MLHCIMPN_01235 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLHCIMPN_01236 1.26e-100 ytkA - - S - - - YtkA-like
MLHCIMPN_01238 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLHCIMPN_01239 1.23e-79 ytkC - - S - - - Bacteriophage holin family
MLHCIMPN_01240 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MLHCIMPN_01241 5.66e-169 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLHCIMPN_01242 3.39e-181 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHCIMPN_01243 1.07e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLHCIMPN_01244 1.84e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLHCIMPN_01245 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MLHCIMPN_01246 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLHCIMPN_01247 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLHCIMPN_01248 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLHCIMPN_01249 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_01250 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLHCIMPN_01251 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MLHCIMPN_01252 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MLHCIMPN_01253 1.49e-184 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
MLHCIMPN_01255 1.26e-136 ytqB - - J - - - Putative rRNA methylase
MLHCIMPN_01256 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MLHCIMPN_01257 1.43e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
MLHCIMPN_01259 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MLHCIMPN_01260 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_01261 4.31e-213 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_01262 2.68e-228 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_01263 2.02e-206 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MLHCIMPN_01264 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_01265 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MLHCIMPN_01266 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_01267 6.12e-222 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MLHCIMPN_01268 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_01269 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MLHCIMPN_01270 1.55e-162 ywaF - - S - - - Integral membrane protein
MLHCIMPN_01271 3.35e-269 yttB - - EGP - - - Major facilitator superfamily
MLHCIMPN_01272 4.59e-175 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLHCIMPN_01273 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
MLHCIMPN_01274 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MLHCIMPN_01275 3.51e-68 ytwF - - P - - - Sulfurtransferase
MLHCIMPN_01276 6.9e-111 - - - M - - - Acetyltransferase (GNAT) domain
MLHCIMPN_01277 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MLHCIMPN_01278 2.88e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_01279 2.44e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHCIMPN_01280 3.24e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MLHCIMPN_01281 7.81e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01282 2.14e-36 yteV - - S - - - Sporulation protein Cse60
MLHCIMPN_01283 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MLHCIMPN_01284 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MLHCIMPN_01285 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_01286 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MLHCIMPN_01287 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MLHCIMPN_01288 2.58e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHCIMPN_01289 1.75e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MLHCIMPN_01290 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MLHCIMPN_01291 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MLHCIMPN_01292 6.81e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MLHCIMPN_01293 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLHCIMPN_01294 1.47e-216 ytlQ - - - - - - -
MLHCIMPN_01295 1.61e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MLHCIMPN_01296 2.93e-199 ytmP - - M - - - Phosphotransferase
MLHCIMPN_01297 5.51e-60 ytzH - - S - - - YtzH-like protein
MLHCIMPN_01298 1.07e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLHCIMPN_01299 4.38e-208 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MLHCIMPN_01300 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MLHCIMPN_01301 9.96e-69 ytzB - - S - - - small secreted protein
MLHCIMPN_01302 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MLHCIMPN_01303 1.94e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MLHCIMPN_01304 5.47e-76 ytpP - - CO - - - Thioredoxin
MLHCIMPN_01305 2.4e-190 ytpQ - - S - - - Belongs to the UPF0354 family
MLHCIMPN_01306 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHCIMPN_01307 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLHCIMPN_01308 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MLHCIMPN_01309 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLHCIMPN_01310 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MLHCIMPN_01311 1.19e-57 ytxJ - - O - - - Protein of unknown function (DUF2847)
MLHCIMPN_01312 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLHCIMPN_01313 1.39e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MLHCIMPN_01314 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MLHCIMPN_01315 4.99e-154 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MLHCIMPN_01316 1.94e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MLHCIMPN_01317 2.06e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MLHCIMPN_01318 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLHCIMPN_01319 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLHCIMPN_01320 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLHCIMPN_01321 8.79e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MLHCIMPN_01322 2.86e-160 ygaZ - - E - - - AzlC protein
MLHCIMPN_01323 9.06e-190 - - - K - - - Transcriptional regulator
MLHCIMPN_01324 1.43e-192 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLHCIMPN_01325 2.39e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MLHCIMPN_01327 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MLHCIMPN_01329 1.58e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLHCIMPN_01330 2.3e-23 - - - - - - - -
MLHCIMPN_01332 7.11e-19 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLHCIMPN_01333 9e-60 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
MLHCIMPN_01335 3.13e-133 yokH - - G - - - SMI1 / KNR4 family
MLHCIMPN_01336 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLHCIMPN_01337 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLHCIMPN_01338 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MLHCIMPN_01339 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MLHCIMPN_01340 2.82e-140 yttP - - K - - - Transcriptional regulator
MLHCIMPN_01341 1.99e-194 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLHCIMPN_01342 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLHCIMPN_01343 9.7e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MLHCIMPN_01344 1.12e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLHCIMPN_01345 2.09e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLHCIMPN_01346 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MLHCIMPN_01347 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLHCIMPN_01348 0.0 ytcJ - - S - - - amidohydrolase
MLHCIMPN_01349 2.32e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLHCIMPN_01350 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MLHCIMPN_01351 2.77e-114 yteJ - - S - - - RDD family
MLHCIMPN_01352 1.22e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
MLHCIMPN_01353 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
MLHCIMPN_01354 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLHCIMPN_01355 8.37e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MLHCIMPN_01356 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLHCIMPN_01357 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MLHCIMPN_01358 2.49e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLHCIMPN_01359 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MLHCIMPN_01361 8.38e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_01362 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
MLHCIMPN_01363 7.89e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
MLHCIMPN_01364 3.57e-62 ytpI - - S - - - YtpI-like protein
MLHCIMPN_01365 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MLHCIMPN_01366 7.04e-32 - - - - - - - -
MLHCIMPN_01367 2.64e-114 ytrI - - - - - - -
MLHCIMPN_01368 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
MLHCIMPN_01369 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MLHCIMPN_01370 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MLHCIMPN_01371 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLHCIMPN_01372 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLHCIMPN_01373 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLHCIMPN_01374 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MLHCIMPN_01375 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLHCIMPN_01376 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
MLHCIMPN_01377 5.65e-96 ytwI - - S - - - membrane
MLHCIMPN_01378 9.5e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MLHCIMPN_01379 1.35e-69 - - - - - - - -
MLHCIMPN_01380 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLHCIMPN_01381 1.08e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MLHCIMPN_01382 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MLHCIMPN_01383 2.38e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_01384 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MLHCIMPN_01385 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLHCIMPN_01386 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLHCIMPN_01387 2.84e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
MLHCIMPN_01388 5.08e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLHCIMPN_01389 4.54e-205 ytbE - - S - - - reductase
MLHCIMPN_01390 8e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MLHCIMPN_01391 1.69e-89 ytcD - - K - - - Transcriptional regulator
MLHCIMPN_01392 1.48e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLHCIMPN_01393 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLHCIMPN_01394 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLHCIMPN_01395 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MLHCIMPN_01396 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MLHCIMPN_01397 1.05e-138 ytxB - - S - - - SNARE associated Golgi protein
MLHCIMPN_01398 1.99e-197 ytxC - - S - - - YtxC-like family
MLHCIMPN_01399 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLHCIMPN_01400 1.2e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MLHCIMPN_01401 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_01402 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MLHCIMPN_01403 1.59e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
MLHCIMPN_01404 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLHCIMPN_01405 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLHCIMPN_01406 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MLHCIMPN_01407 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLHCIMPN_01408 1.34e-56 ysdA - - S - - - Membrane
MLHCIMPN_01409 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
MLHCIMPN_01410 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
MLHCIMPN_01411 1.11e-237 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MLHCIMPN_01412 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MLHCIMPN_01413 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MLHCIMPN_01414 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLHCIMPN_01415 6.57e-180 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MLHCIMPN_01416 1.58e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLHCIMPN_01417 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MLHCIMPN_01418 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
MLHCIMPN_01419 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MLHCIMPN_01420 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MLHCIMPN_01421 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MLHCIMPN_01422 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MLHCIMPN_01423 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
MLHCIMPN_01424 5.07e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MLHCIMPN_01425 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MLHCIMPN_01426 2.2e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLHCIMPN_01427 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLHCIMPN_01428 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLHCIMPN_01429 3.08e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHCIMPN_01430 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLHCIMPN_01431 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
MLHCIMPN_01432 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MLHCIMPN_01433 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLHCIMPN_01434 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
MLHCIMPN_01435 1.12e-93 ywbB - - S - - - Protein of unknown function (DUF2711)
MLHCIMPN_01436 2.11e-50 ywbB - - S - - - Protein of unknown function (DUF2711)
MLHCIMPN_01437 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLHCIMPN_01438 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01439 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MLHCIMPN_01440 1.23e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MLHCIMPN_01441 2.48e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MLHCIMPN_01442 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MLHCIMPN_01443 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MLHCIMPN_01444 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLHCIMPN_01445 1.74e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLHCIMPN_01446 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
MLHCIMPN_01447 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MLHCIMPN_01448 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MLHCIMPN_01449 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MLHCIMPN_01450 8.94e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MLHCIMPN_01451 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01452 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_01453 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MLHCIMPN_01454 5.21e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MLHCIMPN_01455 1.18e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLHCIMPN_01456 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLHCIMPN_01457 9.55e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MLHCIMPN_01462 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MLHCIMPN_01463 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MLHCIMPN_01464 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLHCIMPN_01465 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLHCIMPN_01466 4.12e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLHCIMPN_01467 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLHCIMPN_01468 1.53e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLHCIMPN_01469 3.33e-241 ysoA - - H - - - Tetratricopeptide repeat
MLHCIMPN_01470 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLHCIMPN_01471 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLHCIMPN_01472 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MLHCIMPN_01473 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLHCIMPN_01474 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MLHCIMPN_01475 1.6e-113 ysxD - - - - - - -
MLHCIMPN_01476 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLHCIMPN_01477 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MLHCIMPN_01478 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLHCIMPN_01479 1.56e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MLHCIMPN_01480 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MLHCIMPN_01481 2.68e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MLHCIMPN_01482 3.06e-300 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MLHCIMPN_01483 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLHCIMPN_01484 4.38e-35 - - - - - - - -
MLHCIMPN_01485 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLHCIMPN_01486 2.28e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MLHCIMPN_01487 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLHCIMPN_01488 8.52e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MLHCIMPN_01489 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MLHCIMPN_01490 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MLHCIMPN_01491 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MLHCIMPN_01492 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MLHCIMPN_01493 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MLHCIMPN_01494 4.62e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLHCIMPN_01495 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MLHCIMPN_01496 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MLHCIMPN_01497 4.19e-205 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MLHCIMPN_01498 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MLHCIMPN_01499 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MLHCIMPN_01500 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MLHCIMPN_01501 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MLHCIMPN_01502 2.89e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLHCIMPN_01503 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MLHCIMPN_01504 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MLHCIMPN_01505 1.96e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MLHCIMPN_01506 7.79e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLHCIMPN_01507 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MLHCIMPN_01508 1.23e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MLHCIMPN_01509 4.96e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLHCIMPN_01510 6.31e-250 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MLHCIMPN_01511 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHCIMPN_01513 1.21e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MLHCIMPN_01514 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLHCIMPN_01515 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLHCIMPN_01516 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
MLHCIMPN_01517 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLHCIMPN_01518 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLHCIMPN_01519 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MLHCIMPN_01520 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
MLHCIMPN_01521 4.79e-142 yrbG - - S - - - membrane
MLHCIMPN_01522 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_01523 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
MLHCIMPN_01524 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLHCIMPN_01525 1.26e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MLHCIMPN_01526 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MLHCIMPN_01527 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MLHCIMPN_01528 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLHCIMPN_01529 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLHCIMPN_01530 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLHCIMPN_01531 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MLHCIMPN_01534 4.97e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MLHCIMPN_01535 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLHCIMPN_01536 9.74e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLHCIMPN_01537 7.55e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLHCIMPN_01538 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01539 4.24e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MLHCIMPN_01540 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLHCIMPN_01541 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
MLHCIMPN_01542 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLHCIMPN_01543 3.14e-103 yrrD - - S - - - protein conserved in bacteria
MLHCIMPN_01544 8.4e-42 yrzR - - - - - - -
MLHCIMPN_01545 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
MLHCIMPN_01546 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHCIMPN_01547 1.13e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHCIMPN_01548 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLHCIMPN_01549 4.45e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLHCIMPN_01550 1.15e-237 yrrI - - S - - - AI-2E family transporter
MLHCIMPN_01551 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLHCIMPN_01552 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
MLHCIMPN_01553 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLHCIMPN_01554 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
MLHCIMPN_01555 4.67e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLHCIMPN_01556 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MLHCIMPN_01557 3.64e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MLHCIMPN_01558 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MLHCIMPN_01559 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MLHCIMPN_01560 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLHCIMPN_01561 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MLHCIMPN_01562 2.92e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
MLHCIMPN_01563 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
MLHCIMPN_01564 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLHCIMPN_01565 8.02e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLHCIMPN_01566 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MLHCIMPN_01567 2.56e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLHCIMPN_01568 1.92e-46 yrhC - - S - - - YrhC-like protein
MLHCIMPN_01569 6.49e-104 yrhD - - S - - - Protein of unknown function (DUF1641)
MLHCIMPN_01570 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MLHCIMPN_01571 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MLHCIMPN_01572 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MLHCIMPN_01573 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MLHCIMPN_01574 9.01e-121 yrhH - - Q - - - methyltransferase
MLHCIMPN_01575 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MLHCIMPN_01576 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MLHCIMPN_01577 9.68e-273 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_01578 2.17e-210 yybE - - K - - - Transcriptional regulator
MLHCIMPN_01579 1.13e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLHCIMPN_01580 2.81e-232 romA - - S - - - Beta-lactamase superfamily domain
MLHCIMPN_01581 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MLHCIMPN_01582 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_01583 3.44e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLHCIMPN_01584 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
MLHCIMPN_01585 2.91e-187 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MLHCIMPN_01586 2.06e-190 supH - - S - - - hydrolase
MLHCIMPN_01587 4.76e-121 - - - S - - - DinB family
MLHCIMPN_01588 8.64e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MLHCIMPN_01589 1.95e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_01590 4.56e-34 - - - K - - - acetyltransferase
MLHCIMPN_01591 5.27e-126 yqaC - - F - - - adenylate kinase activity
MLHCIMPN_01592 2.4e-132 yrkN - - K - - - Acetyltransferase (GNAT) family
MLHCIMPN_01594 8.05e-278 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MLHCIMPN_01596 7.69e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
MLHCIMPN_01597 1.27e-306 yrkQ - - T - - - Histidine kinase
MLHCIMPN_01598 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
MLHCIMPN_01599 2.6e-118 - - - K - - - Transcriptional regulator PadR-like family
MLHCIMPN_01600 1.03e-201 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
MLHCIMPN_01601 2.52e-68 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_01602 1.03e-60 - - - D - - - nuclear chromosome segregation
MLHCIMPN_01603 1.63e-77 yqaQ - - L - - - Transposase
MLHCIMPN_01604 3.43e-77 yjcP - - - - - - -
MLHCIMPN_01605 3.83e-61 - - - S - - - YjcQ protein
MLHCIMPN_01606 4.67e-16 - - - - - - - -
MLHCIMPN_01607 7.78e-91 - - - K - - - MerR family transcriptional regulator
MLHCIMPN_01608 1.04e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Aldo/keto reductase family
MLHCIMPN_01610 1.6e-26 xkdR - - S - - - Protein of unknown function (DUF2577)
MLHCIMPN_01611 1.62e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MLHCIMPN_01612 5.83e-35 xkdS - - S - - - Protein of unknown function (DUF2634)
MLHCIMPN_01613 1.67e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_01614 3.28e-279 - - - EGP - - - Transmembrane secretion effector
MLHCIMPN_01615 5.88e-32 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLHCIMPN_01616 4.93e-138 yqeD - - S - - - SNARE associated Golgi protein
MLHCIMPN_01617 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MLHCIMPN_01618 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MLHCIMPN_01620 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MLHCIMPN_01621 3.23e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLHCIMPN_01622 1.2e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLHCIMPN_01623 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MLHCIMPN_01624 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLHCIMPN_01625 6.89e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MLHCIMPN_01626 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLHCIMPN_01627 5.67e-177 yqeM - - Q - - - Methyltransferase
MLHCIMPN_01628 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLHCIMPN_01629 2.81e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MLHCIMPN_01630 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MLHCIMPN_01631 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MLHCIMPN_01632 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MLHCIMPN_01633 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MLHCIMPN_01634 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLHCIMPN_01635 2.14e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MLHCIMPN_01636 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
MLHCIMPN_01637 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLHCIMPN_01638 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MLHCIMPN_01639 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLHCIMPN_01640 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLHCIMPN_01641 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MLHCIMPN_01642 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLHCIMPN_01643 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MLHCIMPN_01644 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLHCIMPN_01645 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MLHCIMPN_01646 1.37e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MLHCIMPN_01647 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MLHCIMPN_01648 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MLHCIMPN_01649 1.28e-293 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MLHCIMPN_01650 4.78e-177 yqfA - - S - - - UPF0365 protein
MLHCIMPN_01651 1.52e-77 yqfB - - - - - - -
MLHCIMPN_01652 3.57e-61 yqfC - - S - - - sporulation protein YqfC
MLHCIMPN_01653 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MLHCIMPN_01654 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MLHCIMPN_01655 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MLHCIMPN_01656 4.13e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLHCIMPN_01657 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MLHCIMPN_01658 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLHCIMPN_01659 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLHCIMPN_01660 6e-24 - - - S - - - YqzL-like protein
MLHCIMPN_01661 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MLHCIMPN_01662 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MLHCIMPN_01663 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MLHCIMPN_01664 5.89e-145 ccpN - - K - - - CBS domain
MLHCIMPN_01665 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLHCIMPN_01666 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MLHCIMPN_01667 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLHCIMPN_01668 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLHCIMPN_01669 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MLHCIMPN_01670 1.72e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MLHCIMPN_01671 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLHCIMPN_01672 1.18e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLHCIMPN_01673 1.77e-78 yqfQ - - S - - - YqfQ-like protein
MLHCIMPN_01674 2.8e-313 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLHCIMPN_01675 9.96e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLHCIMPN_01676 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MLHCIMPN_01677 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_01678 1.3e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MLHCIMPN_01679 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MLHCIMPN_01680 3.34e-80 yqfX - - S - - - membrane
MLHCIMPN_01681 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLHCIMPN_01682 8.76e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
MLHCIMPN_01683 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
MLHCIMPN_01684 1.12e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MLHCIMPN_01685 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MLHCIMPN_01686 5.56e-288 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MLHCIMPN_01687 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MLHCIMPN_01688 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MLHCIMPN_01689 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MLHCIMPN_01690 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MLHCIMPN_01691 5.62e-184 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHCIMPN_01692 5.46e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLHCIMPN_01693 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLHCIMPN_01694 3.42e-68 yqzD - - - - - - -
MLHCIMPN_01695 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MLHCIMPN_01696 8.62e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLHCIMPN_01697 5.38e-11 yqgO - - - - - - -
MLHCIMPN_01698 3.61e-276 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MLHCIMPN_01699 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
MLHCIMPN_01700 7.14e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MLHCIMPN_01701 4.66e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MLHCIMPN_01702 8.94e-255 yqgU - - - - - - -
MLHCIMPN_01703 2.99e-65 dglA - - S - - - Thiamine-binding protein
MLHCIMPN_01704 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
MLHCIMPN_01705 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MLHCIMPN_01706 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MLHCIMPN_01707 1.91e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MLHCIMPN_01709 8.33e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHCIMPN_01710 6.23e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLHCIMPN_01711 2.62e-238 yqxL - - P - - - Mg2 transporter protein
MLHCIMPN_01712 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLHCIMPN_01713 9.79e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MLHCIMPN_01714 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MLHCIMPN_01715 2.27e-93 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
MLHCIMPN_01716 3.14e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MLHCIMPN_01717 2.66e-99 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MLHCIMPN_01718 2.62e-78 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MLHCIMPN_01719 8.16e-36 yqzE - - S - - - YqzE-like protein
MLHCIMPN_01720 2.8e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
MLHCIMPN_01721 1.28e-153 yqxM - - - ko:K19433 - ko00000 -
MLHCIMPN_01722 3.13e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MLHCIMPN_01723 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MLHCIMPN_01724 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MLHCIMPN_01725 2.71e-31 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MLHCIMPN_01726 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
MLHCIMPN_01727 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLHCIMPN_01728 4.04e-265 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MLHCIMPN_01729 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLHCIMPN_01730 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLHCIMPN_01731 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MLHCIMPN_01732 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLHCIMPN_01733 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLHCIMPN_01734 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MLHCIMPN_01735 7.65e-83 yqhP - - - - - - -
MLHCIMPN_01736 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
MLHCIMPN_01737 9.4e-117 yqhR - - S - - - Conserved membrane protein YqhR
MLHCIMPN_01738 2.11e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MLHCIMPN_01739 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLHCIMPN_01740 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
MLHCIMPN_01741 1.27e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MLHCIMPN_01742 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MLHCIMPN_01743 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MLHCIMPN_01744 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MLHCIMPN_01745 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MLHCIMPN_01746 4.27e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MLHCIMPN_01747 2.35e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MLHCIMPN_01748 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MLHCIMPN_01749 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLHCIMPN_01750 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLHCIMPN_01751 1.36e-87 yqhY - - S - - - protein conserved in bacteria
MLHCIMPN_01752 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLHCIMPN_01753 8.75e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLHCIMPN_01754 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHCIMPN_01755 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLHCIMPN_01756 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MLHCIMPN_01757 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLHCIMPN_01758 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MLHCIMPN_01759 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MLHCIMPN_01760 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MLHCIMPN_01761 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MLHCIMPN_01762 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLHCIMPN_01763 2.48e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLHCIMPN_01766 2.28e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLHCIMPN_01768 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
MLHCIMPN_01769 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
MLHCIMPN_01771 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MLHCIMPN_01772 1.1e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLHCIMPN_01773 2.78e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLHCIMPN_01774 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MLHCIMPN_01775 2.06e-259 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MLHCIMPN_01776 2.52e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLHCIMPN_01777 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MLHCIMPN_01778 2.32e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLHCIMPN_01779 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
MLHCIMPN_01780 0.0 bkdR - - KT - - - Transcriptional regulator
MLHCIMPN_01781 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MLHCIMPN_01782 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLHCIMPN_01783 3.45e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MLHCIMPN_01784 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHCIMPN_01785 4.56e-221 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHCIMPN_01786 9.83e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHCIMPN_01787 1.78e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHCIMPN_01788 4.77e-216 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLHCIMPN_01789 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
MLHCIMPN_01790 3.23e-172 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MLHCIMPN_01791 4.25e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MLHCIMPN_01792 2.89e-163 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLHCIMPN_01793 4.58e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MLHCIMPN_01794 3.45e-85 yqjB - - S - - - protein conserved in bacteria
MLHCIMPN_01796 1.33e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MLHCIMPN_01797 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLHCIMPN_01798 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MLHCIMPN_01799 1.68e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHCIMPN_01800 1.3e-34 yqzJ - - - - - - -
MLHCIMPN_01801 1.92e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLHCIMPN_01802 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLHCIMPN_01803 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLHCIMPN_01804 3.37e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLHCIMPN_01805 1.29e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLHCIMPN_01806 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLHCIMPN_01807 6.43e-66 - - - S - - - GlpM protein
MLHCIMPN_01808 1.42e-196 - - - K - - - LysR substrate binding domain
MLHCIMPN_01809 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MLHCIMPN_01810 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_01813 1.85e-312 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLHCIMPN_01814 7.97e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLHCIMPN_01832 4.79e-259 - - - C - - - Na+/H+ antiporter family
MLHCIMPN_01833 1.57e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MLHCIMPN_01834 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLHCIMPN_01835 0.0 ygaK - - C - - - Berberine and berberine like
MLHCIMPN_01837 9.91e-288 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
MLHCIMPN_01838 1.17e-178 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHCIMPN_01839 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_01840 3.14e-169 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_01841 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_01842 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLHCIMPN_01843 4.68e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
MLHCIMPN_01844 1.5e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLHCIMPN_01845 7.12e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MLHCIMPN_01846 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_01847 1.17e-270 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MLHCIMPN_01848 3.39e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLHCIMPN_01849 1.29e-106 ygaO - - - - - - -
MLHCIMPN_01850 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01852 7.82e-147 yhzB - - S - - - B3/4 domain
MLHCIMPN_01853 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLHCIMPN_01854 2.08e-225 yhbB - - S - - - Putative amidase domain
MLHCIMPN_01855 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLHCIMPN_01856 4.63e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
MLHCIMPN_01857 3.99e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MLHCIMPN_01858 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MLHCIMPN_01859 1.23e-07 - - - - - - - -
MLHCIMPN_01860 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MLHCIMPN_01861 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MLHCIMPN_01862 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MLHCIMPN_01863 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MLHCIMPN_01864 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MLHCIMPN_01865 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MLHCIMPN_01866 1.41e-72 yhcC - - - - - - -
MLHCIMPN_01867 1.6e-89 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_01868 2.23e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHCIMPN_01869 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MLHCIMPN_01870 5.86e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MLHCIMPN_01871 1.01e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MLHCIMPN_01872 4.31e-292 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHCIMPN_01873 1.74e-72 yhcM - - - - - - -
MLHCIMPN_01874 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHCIMPN_01875 1.85e-204 yhcP - - - - - - -
MLHCIMPN_01876 4.45e-151 yhcQ - - M - - - Spore coat protein
MLHCIMPN_01877 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLHCIMPN_01878 1.3e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MLHCIMPN_01879 2.27e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLHCIMPN_01880 7.37e-90 yhcU - - S - - - Family of unknown function (DUF5365)
MLHCIMPN_01881 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
MLHCIMPN_01882 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
MLHCIMPN_01883 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLHCIMPN_01884 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLHCIMPN_01885 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLHCIMPN_01886 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MLHCIMPN_01887 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLHCIMPN_01888 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLHCIMPN_01889 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MLHCIMPN_01890 8.75e-262 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_01891 1.56e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_01892 9.77e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MLHCIMPN_01893 1.16e-51 yhdB - - S - - - YhdB-like protein
MLHCIMPN_01894 2.94e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
MLHCIMPN_01895 1.04e-297 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLHCIMPN_01896 3.79e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MLHCIMPN_01897 0.0 ygxB - - M - - - Conserved TM helix
MLHCIMPN_01898 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MLHCIMPN_01899 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MLHCIMPN_01900 2.8e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MLHCIMPN_01901 8.17e-209 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01902 6.39e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MLHCIMPN_01903 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_01904 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
MLHCIMPN_01905 8.02e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLHCIMPN_01906 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
MLHCIMPN_01907 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
MLHCIMPN_01908 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MLHCIMPN_01909 9.21e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLHCIMPN_01910 2.28e-306 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLHCIMPN_01911 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MLHCIMPN_01912 4.05e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MLHCIMPN_01913 9.1e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLHCIMPN_01914 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MLHCIMPN_01915 2.9e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHCIMPN_01916 4.97e-79 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLHCIMPN_01917 1.49e-164 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MLHCIMPN_01918 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
MLHCIMPN_01919 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MLHCIMPN_01920 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLHCIMPN_01921 4.01e-200 nodB1 - - G - - - deacetylase
MLHCIMPN_01922 3.99e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLHCIMPN_01923 1.43e-113 pksA - - K - - - Transcriptional regulator
MLHCIMPN_01924 3.12e-123 ymcC - - S - - - Membrane
MLHCIMPN_01925 2.49e-110 - - - T - - - universal stress protein
MLHCIMPN_01927 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHCIMPN_01928 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MLHCIMPN_01929 7.8e-142 yheG - - GM - - - NAD(P)H-binding
MLHCIMPN_01931 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
MLHCIMPN_01932 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
MLHCIMPN_01933 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MLHCIMPN_01934 1.54e-272 yheC - - HJ - - - YheC/D like ATP-grasp
MLHCIMPN_01935 7.84e-264 yheB - - S - - - Belongs to the UPF0754 family
MLHCIMPN_01936 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
MLHCIMPN_01937 1.74e-258 yhaZ - - L - - - DNA alkylation repair enzyme
MLHCIMPN_01938 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MLHCIMPN_01939 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MLHCIMPN_01940 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
MLHCIMPN_01941 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MLHCIMPN_01942 3.62e-111 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MLHCIMPN_01944 1.18e-174 yhaR - - I - - - enoyl-CoA hydratase
MLHCIMPN_01945 5.99e-21 - - - S - - - YhzD-like protein
MLHCIMPN_01946 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_01947 4.82e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MLHCIMPN_01948 7.47e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MLHCIMPN_01949 0.0 yhaN - - L - - - AAA domain
MLHCIMPN_01950 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MLHCIMPN_01951 4.95e-44 yhaL - - S - - - Sporulation protein YhaL
MLHCIMPN_01952 1.36e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLHCIMPN_01953 1.29e-123 yhaK - - S - - - Putative zincin peptidase
MLHCIMPN_01954 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
MLHCIMPN_01955 4.73e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MLHCIMPN_01956 4.74e-55 yhaH - - S - - - YtxH-like protein
MLHCIMPN_01957 2.55e-24 - - - - - - - -
MLHCIMPN_01958 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
MLHCIMPN_01959 5.91e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLHCIMPN_01960 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLHCIMPN_01961 3.02e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MLHCIMPN_01962 6.41e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MLHCIMPN_01963 1.75e-161 ecsC - - S - - - EcsC protein family
MLHCIMPN_01964 1.53e-286 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLHCIMPN_01965 3.98e-311 yhfA - - C - - - membrane
MLHCIMPN_01966 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MLHCIMPN_01967 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLHCIMPN_01968 8.58e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLHCIMPN_01969 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MLHCIMPN_01970 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLHCIMPN_01971 4.41e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_01972 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MLHCIMPN_01973 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHCIMPN_01975 2.11e-250 yhfE - - G - - - peptidase M42
MLHCIMPN_01976 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLHCIMPN_01978 4.01e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLHCIMPN_01979 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MLHCIMPN_01980 1.05e-141 yhfK - - GM - - - NmrA-like family
MLHCIMPN_01981 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MLHCIMPN_01982 7.96e-85 yhfM - - - - - - -
MLHCIMPN_01983 3.56e-298 yhfN - - O - - - Peptidase M48
MLHCIMPN_01984 1.57e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLHCIMPN_01985 7.33e-192 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLHCIMPN_01986 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MLHCIMPN_01987 2.38e-251 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MLHCIMPN_01988 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MLHCIMPN_01989 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MLHCIMPN_01990 1.87e-275 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MLHCIMPN_01991 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MLHCIMPN_01992 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_01993 3.87e-42 yhzC - - S - - - IDEAL
MLHCIMPN_01994 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MLHCIMPN_01995 2.09e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MLHCIMPN_01996 4.93e-82 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MLHCIMPN_01997 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
MLHCIMPN_01998 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
MLHCIMPN_01999 2.64e-63 - - - S - - - Belongs to the UPF0145 family
MLHCIMPN_02000 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLHCIMPN_02001 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
MLHCIMPN_02002 4.12e-79 yhjD - - - - - - -
MLHCIMPN_02003 2.23e-142 yhjE - - S - - - SNARE associated Golgi protein
MLHCIMPN_02004 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLHCIMPN_02005 0.0 yhjG - - CH - - - FAD binding domain
MLHCIMPN_02006 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_02007 9.85e-262 yhjN - - S ko:K07120 - ko00000 membrane
MLHCIMPN_02008 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_02009 1.06e-139 - - - K - - - QacR-like protein, C-terminal region
MLHCIMPN_02010 3.6e-122 yhjR - - S - - - Rubrerythrin
MLHCIMPN_02011 5.11e-153 ydfS - - S - - - Protein of unknown function (DUF421)
MLHCIMPN_02012 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MLHCIMPN_02013 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MLHCIMPN_02014 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLHCIMPN_02015 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MLHCIMPN_02016 6.24e-66 yisB - - V - - - COG1403 Restriction endonuclease
MLHCIMPN_02017 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MLHCIMPN_02018 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MLHCIMPN_02019 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MLHCIMPN_02020 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MLHCIMPN_02021 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
MLHCIMPN_02022 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MLHCIMPN_02023 1.59e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
MLHCIMPN_02024 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLHCIMPN_02025 2.22e-78 yisL - - S - - - UPF0344 protein
MLHCIMPN_02026 2.17e-123 yisN - - S - - - Protein of unknown function (DUF2777)
MLHCIMPN_02027 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MLHCIMPN_02028 1.81e-169 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MLHCIMPN_02029 6.12e-312 yisQ - - V - - - Mate efflux family protein
MLHCIMPN_02030 4.72e-206 yisR - - K - - - Transcriptional regulator
MLHCIMPN_02031 4.31e-31 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MLHCIMPN_02032 1.48e-114 yisT - - S - - - DinB family
MLHCIMPN_02033 1.71e-95 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MLHCIMPN_02034 5.57e-238 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHCIMPN_02035 1.6e-103 yisX - - S - - - Pentapeptide repeats (9 copies)
MLHCIMPN_02036 1.8e-104 - - - S - - - Acetyltransferase (GNAT) domain
MLHCIMPN_02037 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLHCIMPN_02038 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MLHCIMPN_02039 7.54e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MLHCIMPN_02040 8.51e-219 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
MLHCIMPN_02041 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MLHCIMPN_02042 1.79e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MLHCIMPN_02044 5.5e-203 yitS - - S - - - protein conserved in bacteria
MLHCIMPN_02045 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_02046 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
MLHCIMPN_02047 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
MLHCIMPN_02048 1.49e-11 - - - - - - - -
MLHCIMPN_02049 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MLHCIMPN_02050 8.73e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MLHCIMPN_02051 1.33e-67 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MLHCIMPN_02052 1.12e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLHCIMPN_02053 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MLHCIMPN_02054 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
MLHCIMPN_02055 5.84e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLHCIMPN_02056 2.99e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLHCIMPN_02057 5.17e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MLHCIMPN_02058 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MLHCIMPN_02059 2.31e-257 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLHCIMPN_02060 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MLHCIMPN_02061 8.28e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLHCIMPN_02062 7.21e-39 yjzC - - S - - - YjzC-like protein
MLHCIMPN_02063 1.24e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
MLHCIMPN_02064 3.04e-176 yjaU - - I - - - carboxylic ester hydrolase activity
MLHCIMPN_02065 1.67e-134 yjaV - - - - - - -
MLHCIMPN_02066 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MLHCIMPN_02067 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MLHCIMPN_02068 2.72e-42 yjzB - - - - - - -
MLHCIMPN_02069 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLHCIMPN_02070 9.08e-299 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLHCIMPN_02071 7.48e-190 yjaZ - - O - - - Zn-dependent protease
MLHCIMPN_02072 8.37e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02073 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02074 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MLHCIMPN_02075 5.76e-217 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02076 1.67e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02077 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
MLHCIMPN_02078 4.85e-232 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MLHCIMPN_02079 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLHCIMPN_02080 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02081 6.93e-208 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02082 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02083 1.42e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02084 3.5e-295 - - - S - - - Putative glycosyl hydrolase domain
MLHCIMPN_02085 2.55e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHCIMPN_02086 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLHCIMPN_02087 4.59e-140 yjbE - - P - - - Integral membrane protein TerC family
MLHCIMPN_02088 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLHCIMPN_02089 9.45e-281 coiA - - S ko:K06198 - ko00000 Competence protein
MLHCIMPN_02090 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MLHCIMPN_02091 1.06e-25 - - - - - - - -
MLHCIMPN_02092 1.22e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MLHCIMPN_02093 2.03e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MLHCIMPN_02094 3.12e-152 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLHCIMPN_02095 1.72e-128 yjbK - - S - - - protein conserved in bacteria
MLHCIMPN_02096 4.78e-79 yjbL - - S - - - Belongs to the UPF0738 family
MLHCIMPN_02097 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MLHCIMPN_02098 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLHCIMPN_02099 2.35e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MLHCIMPN_02100 3.05e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLHCIMPN_02101 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLHCIMPN_02102 5.26e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLHCIMPN_02103 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MLHCIMPN_02104 4.57e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MLHCIMPN_02105 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
MLHCIMPN_02106 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLHCIMPN_02107 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLHCIMPN_02108 4.3e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLHCIMPN_02109 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MLHCIMPN_02110 7.96e-124 yjbX - - S - - - Spore coat protein
MLHCIMPN_02111 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MLHCIMPN_02112 2.48e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MLHCIMPN_02113 1.51e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MLHCIMPN_02114 4.1e-43 cotW - - - ko:K06341 - ko00000 -
MLHCIMPN_02115 9.7e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MLHCIMPN_02116 8.37e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
MLHCIMPN_02119 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLHCIMPN_02120 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
MLHCIMPN_02121 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLHCIMPN_02122 2.48e-48 - - - - - - - -
MLHCIMPN_02123 2.06e-181 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MLHCIMPN_02124 4.59e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLHCIMPN_02125 3.53e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLHCIMPN_02126 4.32e-48 - - - K - - - SpoVT / AbrB like domain
MLHCIMPN_02127 2.48e-96 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHCIMPN_02128 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MLHCIMPN_02129 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MLHCIMPN_02130 3.93e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLHCIMPN_02131 1.37e-271 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MLHCIMPN_02133 1.14e-26 - - - - - - - -
MLHCIMPN_02134 1.42e-29 - - - - - - - -
MLHCIMPN_02135 9.34e-51 - - - - - - - -
MLHCIMPN_02137 4.74e-247 - - - M - - - nucleic acid phosphodiester bond hydrolysis
MLHCIMPN_02141 3.27e-78 - - - E - - - Glyoxalase-like domain
MLHCIMPN_02142 1.64e-210 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MLHCIMPN_02143 3.12e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MLHCIMPN_02144 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MLHCIMPN_02145 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_02146 1.34e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MLHCIMPN_02147 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLHCIMPN_02148 2.09e-242 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLHCIMPN_02149 4.28e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLHCIMPN_02150 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHCIMPN_02151 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_02152 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHCIMPN_02153 1.62e-176 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLHCIMPN_02154 1.62e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
MLHCIMPN_02155 1.69e-46 - - - - - - - -
MLHCIMPN_02156 1.19e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_02157 2.89e-135 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MLHCIMPN_02159 1.91e-31 yjfB - - S - - - Putative motility protein
MLHCIMPN_02160 1.48e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
MLHCIMPN_02161 3.92e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
MLHCIMPN_02162 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
MLHCIMPN_02163 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
MLHCIMPN_02164 3.25e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLHCIMPN_02165 1.64e-283 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLHCIMPN_02166 1.73e-40 - - - - - - - -
MLHCIMPN_02167 3.93e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MLHCIMPN_02168 3.6e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MLHCIMPN_02169 3.08e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02170 2.38e-226 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MLHCIMPN_02171 4.96e-118 yjlB - - S - - - Cupin domain
MLHCIMPN_02172 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MLHCIMPN_02173 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLHCIMPN_02174 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MLHCIMPN_02175 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
MLHCIMPN_02176 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MLHCIMPN_02177 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
MLHCIMPN_02178 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MLHCIMPN_02179 1.83e-112 - - - T - - - Transcriptional regulatory protein, C terminal
MLHCIMPN_02180 4.91e-167 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MLHCIMPN_02181 1.11e-132 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_02182 7.74e-86 - - - S - - - ABC-2 family transporter protein
MLHCIMPN_02184 4.67e-50 - 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02185 1.26e-75 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_02187 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
MLHCIMPN_02188 2.77e-276 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
MLHCIMPN_02191 3.25e-243 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
MLHCIMPN_02192 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MLHCIMPN_02193 8.38e-103 yjoA - - S - - - DinB family
MLHCIMPN_02194 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MLHCIMPN_02196 1.94e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MLHCIMPN_02197 9.51e-81 yjqA - - S - - - Bacterial PH domain
MLHCIMPN_02198 2.63e-142 yjqB - - S - - - phage-related replication protein
MLHCIMPN_02199 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
MLHCIMPN_02200 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
MLHCIMPN_02202 2.94e-194 xkdC - - L - - - Bacterial dnaA protein
MLHCIMPN_02206 3.05e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLHCIMPN_02207 1.24e-142 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MLHCIMPN_02208 1.36e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MLHCIMPN_02209 5.17e-304 xkdE3 - - S - - - portal protein
MLHCIMPN_02210 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
MLHCIMPN_02211 8.3e-203 xkdG - - S - - - Phage capsid family
MLHCIMPN_02212 3.6e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
MLHCIMPN_02213 1.42e-56 - - - S - - - Domain of unknown function (DUF3599)
MLHCIMPN_02214 8.03e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MLHCIMPN_02215 1.05e-74 xkdJ - - - - - - -
MLHCIMPN_02216 1.45e-20 - - - - - - - -
MLHCIMPN_02217 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
MLHCIMPN_02218 8.21e-97 xkdM - - S - - - Phage tail tube protein
MLHCIMPN_02219 2.09e-95 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MLHCIMPN_02220 4.33e-27 - - - - - - - -
MLHCIMPN_02221 5.5e-272 xkdO - - L - - - Transglycosylase SLT domain
MLHCIMPN_02222 6.56e-145 xkdP - - S - - - Lysin motif
MLHCIMPN_02223 2.66e-206 xkdQ - - G - - - NLP P60 protein
MLHCIMPN_02224 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
MLHCIMPN_02225 4.74e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
MLHCIMPN_02226 4.38e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLHCIMPN_02227 4.1e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MLHCIMPN_02228 8.92e-38 - - - - - - - -
MLHCIMPN_02229 4.87e-109 - - - - - - - -
MLHCIMPN_02231 1.32e-39 xkdX - - - - - - -
MLHCIMPN_02232 3.67e-177 xepA - - - - - - -
MLHCIMPN_02233 3.87e-51 xhlA - - S - - - Haemolysin XhlA
MLHCIMPN_02234 4.7e-52 xhlB - - S - - - SPP1 phage holin
MLHCIMPN_02235 2.02e-214 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MLHCIMPN_02236 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MLHCIMPN_02237 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MLHCIMPN_02238 1.22e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
MLHCIMPN_02239 1.2e-140 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLHCIMPN_02240 2.64e-311 steT - - E ko:K03294 - ko00000 amino acid
MLHCIMPN_02241 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MLHCIMPN_02242 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLHCIMPN_02243 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHCIMPN_02245 1.07e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHCIMPN_02246 0.0 yubD - - P - - - Major Facilitator Superfamily
MLHCIMPN_02247 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MLHCIMPN_02248 3.98e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02249 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLHCIMPN_02250 4.37e-241 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02251 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLHCIMPN_02252 1.09e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MLHCIMPN_02253 4.3e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MLHCIMPN_02254 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLHCIMPN_02255 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_02256 3.43e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MLHCIMPN_02257 3.44e-203 ykgA - - E - - - Amidinotransferase
MLHCIMPN_02258 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
MLHCIMPN_02259 7.43e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLHCIMPN_02260 2.37e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MLHCIMPN_02261 4.97e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MLHCIMPN_02262 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLHCIMPN_02263 1.77e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLHCIMPN_02264 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLHCIMPN_02265 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
MLHCIMPN_02266 9.88e-111 ohrR - - K - - - COG1846 Transcriptional regulators
MLHCIMPN_02267 3.2e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
MLHCIMPN_02268 6.7e-82 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLHCIMPN_02270 7.1e-275 - - - M - - - Glycosyl transferase family 2
MLHCIMPN_02271 1.78e-175 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
MLHCIMPN_02272 1.98e-133 - - - S - - - AAA ATPase domain
MLHCIMPN_02273 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLHCIMPN_02274 2.58e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLHCIMPN_02275 1.28e-189 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLHCIMPN_02276 2.18e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MLHCIMPN_02277 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_02278 4.66e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MLHCIMPN_02279 1.27e-309 ydhD - - M - - - Glycosyl hydrolase
MLHCIMPN_02281 3.52e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MLHCIMPN_02282 1.23e-69 tnrA - - K - - - transcriptional
MLHCIMPN_02283 1.11e-23 - - - - - - - -
MLHCIMPN_02284 5.25e-37 ykoL - - - - - - -
MLHCIMPN_02285 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MLHCIMPN_02286 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
MLHCIMPN_02287 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MLHCIMPN_02288 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLHCIMPN_02289 1.43e-131 ykoX - - S - - - membrane-associated protein
MLHCIMPN_02290 2.91e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLHCIMPN_02291 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_02292 3.6e-250 ykrI - - S - - - Anti-sigma factor N-terminus
MLHCIMPN_02293 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MLHCIMPN_02294 1.62e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
MLHCIMPN_02295 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MLHCIMPN_02296 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MLHCIMPN_02297 3e-148 - - - S - - - Protein of unknown function (DUF421)
MLHCIMPN_02298 3.07e-32 ykzE - - - - - - -
MLHCIMPN_02299 3.74e-241 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLHCIMPN_02300 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02301 1.31e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLHCIMPN_02303 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLHCIMPN_02304 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLHCIMPN_02305 1.57e-190 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLHCIMPN_02306 1.04e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHCIMPN_02307 7.51e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLHCIMPN_02308 9.47e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLHCIMPN_02309 2.61e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLHCIMPN_02310 2.05e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLHCIMPN_02312 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLHCIMPN_02313 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MLHCIMPN_02314 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MLHCIMPN_02315 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MLHCIMPN_02316 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MLHCIMPN_02317 1.73e-228 ykvI - - S - - - membrane
MLHCIMPN_02318 6.57e-254 - - - - - - - -
MLHCIMPN_02319 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLHCIMPN_02320 6.25e-103 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MLHCIMPN_02321 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLHCIMPN_02322 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLHCIMPN_02324 2.54e-77 ykvN - - K - - - Transcriptional regulator
MLHCIMPN_02325 2.47e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHCIMPN_02326 3.91e-42 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLHCIMPN_02327 6e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
MLHCIMPN_02328 5.43e-35 ykvS - - S - - - protein conserved in bacteria
MLHCIMPN_02329 7.17e-39 - - - - - - - -
MLHCIMPN_02330 8.42e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MLHCIMPN_02331 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_02332 8.57e-114 stoA - - CO - - - thiol-disulfide
MLHCIMPN_02333 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MLHCIMPN_02334 4.71e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MLHCIMPN_02336 1.01e-224 ykvZ - - K - - - Transcriptional regulator
MLHCIMPN_02337 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MLHCIMPN_02338 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_02339 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MLHCIMPN_02340 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLHCIMPN_02341 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_02342 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MLHCIMPN_02343 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLHCIMPN_02344 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLHCIMPN_02345 2.94e-168 ykwD - - J - - - protein with SCP PR1 domains
MLHCIMPN_02346 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLHCIMPN_02347 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02348 3.28e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MLHCIMPN_02349 6.38e-15 - - - - - - - -
MLHCIMPN_02350 3.2e-212 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MLHCIMPN_02351 5.07e-108 ykyB - - S - - - YkyB-like protein
MLHCIMPN_02352 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_02353 2.55e-116 ykuD - - S - - - protein conserved in bacteria
MLHCIMPN_02354 3.66e-197 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MLHCIMPN_02355 1.5e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_02357 1.82e-295 ykuI - - T - - - Diguanylate phosphodiesterase
MLHCIMPN_02358 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
MLHCIMPN_02359 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
MLHCIMPN_02360 3.09e-35 ykzF - - S - - - Antirepressor AbbA
MLHCIMPN_02361 8.55e-99 ykuL - - S - - - CBS domain
MLHCIMPN_02362 1.32e-215 ccpC - - K - - - Transcriptional regulator
MLHCIMPN_02363 6.12e-115 ykuN - - C ko:K03839 - ko00000 Flavodoxin
MLHCIMPN_02364 1.95e-219 ykuO - - - - - - -
MLHCIMPN_02365 2.16e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
MLHCIMPN_02366 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLHCIMPN_02367 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLHCIMPN_02368 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
MLHCIMPN_02369 1.73e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MLHCIMPN_02370 1.92e-102 ykuV - - CO - - - thiol-disulfide
MLHCIMPN_02371 3.04e-126 rok - - K - - - Repressor of ComK
MLHCIMPN_02372 6.93e-216 yknT - - - ko:K06437 - ko00000 -
MLHCIMPN_02373 1.93e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLHCIMPN_02374 1.41e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLHCIMPN_02375 2.78e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MLHCIMPN_02376 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MLHCIMPN_02377 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MLHCIMPN_02378 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLHCIMPN_02379 7.69e-139 yknW - - S - - - Yip1 domain
MLHCIMPN_02380 1.64e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLHCIMPN_02381 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_02382 2.98e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_02383 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_02384 5.54e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MLHCIMPN_02385 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLHCIMPN_02386 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MLHCIMPN_02387 3.68e-50 ykoA - - - - - - -
MLHCIMPN_02388 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLHCIMPN_02389 1.08e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHCIMPN_02390 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLHCIMPN_02391 4.47e-18 - - - S - - - Uncharacterized protein YkpC
MLHCIMPN_02392 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MLHCIMPN_02393 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MLHCIMPN_02394 1.68e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLHCIMPN_02395 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MLHCIMPN_02396 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MLHCIMPN_02397 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLHCIMPN_02398 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHCIMPN_02399 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
MLHCIMPN_02400 1.51e-187 ykrA - - S - - - hydrolases of the HAD superfamily
MLHCIMPN_02401 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLHCIMPN_02402 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLHCIMPN_02403 1.32e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
MLHCIMPN_02404 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_02405 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02406 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
MLHCIMPN_02407 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02408 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02409 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02410 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02411 0.0 - - - IQ - - - Phosphopantetheine attachment site
MLHCIMPN_02412 3.73e-264 - - - V - - - Beta-lactamase
MLHCIMPN_02413 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLHCIMPN_02414 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLHCIMPN_02415 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLHCIMPN_02416 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLHCIMPN_02417 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MLHCIMPN_02418 8.08e-192 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MLHCIMPN_02419 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MLHCIMPN_02420 3.83e-56 yktA - - S - - - Belongs to the UPF0223 family
MLHCIMPN_02421 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
MLHCIMPN_02422 3.33e-33 ykzI - - - - - - -
MLHCIMPN_02423 7.8e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MLHCIMPN_02424 1.07e-107 ykzC - - S - - - Acetyltransferase (GNAT) family
MLHCIMPN_02425 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MLHCIMPN_02427 2.83e-62 ylaE - - - - - - -
MLHCIMPN_02428 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
MLHCIMPN_02429 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MLHCIMPN_02430 2.44e-65 - - - S - - - YlaH-like protein
MLHCIMPN_02431 6.78e-46 ylaI - - S - - - protein conserved in bacteria
MLHCIMPN_02432 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLHCIMPN_02433 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MLHCIMPN_02434 1.75e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLHCIMPN_02435 5.18e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MLHCIMPN_02436 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
MLHCIMPN_02437 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLHCIMPN_02438 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLHCIMPN_02439 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLHCIMPN_02440 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLHCIMPN_02441 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLHCIMPN_02442 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLHCIMPN_02443 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLHCIMPN_02444 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLHCIMPN_02445 8.46e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MLHCIMPN_02446 4.12e-79 ylbA - - S - - - YugN-like family
MLHCIMPN_02447 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
MLHCIMPN_02448 3.97e-255 ylbC - - S - - - protein with SCP PR1 domains
MLHCIMPN_02449 1.03e-87 ylbD - - S - - - Putative coat protein
MLHCIMPN_02450 1.73e-48 ylbE - - S - - - YlbE-like protein
MLHCIMPN_02451 2.74e-96 ylbF - - S - - - Belongs to the UPF0342 family
MLHCIMPN_02452 3.94e-57 ylbG - - S - - - UPF0298 protein
MLHCIMPN_02453 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MLHCIMPN_02454 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLHCIMPN_02455 9.73e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MLHCIMPN_02456 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MLHCIMPN_02457 8.8e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MLHCIMPN_02458 5.23e-295 ylbM - - S - - - Belongs to the UPF0348 family
MLHCIMPN_02459 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MLHCIMPN_02460 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MLHCIMPN_02461 1.27e-110 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLHCIMPN_02462 1.14e-116 ylbP - - K - - - n-acetyltransferase
MLHCIMPN_02463 2.85e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHCIMPN_02464 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLHCIMPN_02465 1.03e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MLHCIMPN_02466 8.23e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLHCIMPN_02467 2.4e-68 ftsL - - D - - - Essential cell division protein
MLHCIMPN_02468 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MLHCIMPN_02469 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MLHCIMPN_02470 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLHCIMPN_02471 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLHCIMPN_02472 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLHCIMPN_02473 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLHCIMPN_02474 3.29e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLHCIMPN_02475 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MLHCIMPN_02476 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLHCIMPN_02477 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLHCIMPN_02478 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLHCIMPN_02479 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MLHCIMPN_02480 8.23e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLHCIMPN_02481 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_02482 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_02483 8.04e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLHCIMPN_02484 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MLHCIMPN_02485 7.13e-52 ylmC - - S - - - sporulation protein
MLHCIMPN_02486 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MLHCIMPN_02487 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLHCIMPN_02488 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLHCIMPN_02489 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MLHCIMPN_02490 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
MLHCIMPN_02491 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MLHCIMPN_02492 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLHCIMPN_02493 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
MLHCIMPN_02494 1.02e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLHCIMPN_02495 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MLHCIMPN_02496 8.98e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLHCIMPN_02497 2.81e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MLHCIMPN_02498 1.47e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MLHCIMPN_02499 1.55e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLHCIMPN_02500 8.86e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MLHCIMPN_02501 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MLHCIMPN_02502 1.18e-179 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLHCIMPN_02503 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLHCIMPN_02504 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLHCIMPN_02505 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLHCIMPN_02507 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MLHCIMPN_02508 1.21e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MLHCIMPN_02509 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MLHCIMPN_02510 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MLHCIMPN_02511 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MLHCIMPN_02512 4.15e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MLHCIMPN_02513 6.27e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MLHCIMPN_02514 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MLHCIMPN_02515 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MLHCIMPN_02516 2.14e-198 yloC - - S - - - stress-induced protein
MLHCIMPN_02517 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MLHCIMPN_02518 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MLHCIMPN_02519 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLHCIMPN_02520 2.09e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLHCIMPN_02521 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLHCIMPN_02522 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLHCIMPN_02523 2.64e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLHCIMPN_02524 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLHCIMPN_02525 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLHCIMPN_02526 2.03e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MLHCIMPN_02527 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MLHCIMPN_02528 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLHCIMPN_02529 3.42e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MLHCIMPN_02530 4.34e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MLHCIMPN_02531 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MLHCIMPN_02532 3.65e-78 yloU - - S - - - protein conserved in bacteria
MLHCIMPN_02533 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MLHCIMPN_02534 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MLHCIMPN_02535 9.75e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MLHCIMPN_02536 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLHCIMPN_02537 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLHCIMPN_02538 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLHCIMPN_02539 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_02540 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MLHCIMPN_02541 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLHCIMPN_02542 1.23e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLHCIMPN_02543 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MLHCIMPN_02544 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLHCIMPN_02545 1.57e-184 - - - S - - - Phosphotransferase enzyme family
MLHCIMPN_02546 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLHCIMPN_02547 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLHCIMPN_02548 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MLHCIMPN_02549 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MLHCIMPN_02550 3.41e-80 ylqD - - S - - - YlqD protein
MLHCIMPN_02551 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLHCIMPN_02552 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MLHCIMPN_02553 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLHCIMPN_02554 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLHCIMPN_02555 3.37e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLHCIMPN_02556 0.0 ylqG - - - - - - -
MLHCIMPN_02557 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MLHCIMPN_02558 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLHCIMPN_02559 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLHCIMPN_02560 7.32e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MLHCIMPN_02561 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLHCIMPN_02562 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLHCIMPN_02563 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MLHCIMPN_02564 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLHCIMPN_02565 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLHCIMPN_02566 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLHCIMPN_02567 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLHCIMPN_02568 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MLHCIMPN_02569 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MLHCIMPN_02570 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MLHCIMPN_02571 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHCIMPN_02572 1.96e-122 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MLHCIMPN_02573 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLHCIMPN_02574 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MLHCIMPN_02575 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
MLHCIMPN_02576 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MLHCIMPN_02577 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MLHCIMPN_02578 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MLHCIMPN_02579 1.81e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MLHCIMPN_02580 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHCIMPN_02581 8.47e-245 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLHCIMPN_02582 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MLHCIMPN_02583 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MLHCIMPN_02584 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MLHCIMPN_02585 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MLHCIMPN_02586 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MLHCIMPN_02587 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLHCIMPN_02588 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLHCIMPN_02589 7.94e-250 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MLHCIMPN_02590 6.35e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MLHCIMPN_02591 1.42e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLHCIMPN_02592 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MLHCIMPN_02593 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MLHCIMPN_02594 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLHCIMPN_02595 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLHCIMPN_02596 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLHCIMPN_02597 5.85e-94 ylxL - - - - - - -
MLHCIMPN_02598 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MLHCIMPN_02599 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLHCIMPN_02600 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MLHCIMPN_02601 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLHCIMPN_02602 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLHCIMPN_02603 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MLHCIMPN_02604 2.57e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLHCIMPN_02605 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MLHCIMPN_02606 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLHCIMPN_02607 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLHCIMPN_02608 1.9e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MLHCIMPN_02609 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MLHCIMPN_02610 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MLHCIMPN_02611 6.16e-63 ylxQ - - J - - - ribosomal protein
MLHCIMPN_02612 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLHCIMPN_02613 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MLHCIMPN_02614 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLHCIMPN_02615 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLHCIMPN_02616 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MLHCIMPN_02617 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLHCIMPN_02618 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLHCIMPN_02619 4.15e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MLHCIMPN_02620 5.91e-299 mlpA - - S - - - Belongs to the peptidase M16 family
MLHCIMPN_02621 2.17e-56 ymxH - - S - - - YlmC YmxH family
MLHCIMPN_02622 4.51e-204 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MLHCIMPN_02623 1.36e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLHCIMPN_02624 1.74e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLHCIMPN_02625 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MLHCIMPN_02626 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLHCIMPN_02627 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLHCIMPN_02628 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MLHCIMPN_02629 6.32e-42 - - - S - - - YlzJ-like protein
MLHCIMPN_02630 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MLHCIMPN_02631 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_02632 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_02633 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MLHCIMPN_02634 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MLHCIMPN_02635 1.12e-306 albE - - S - - - Peptidase M16
MLHCIMPN_02636 8.28e-310 ymfH - - S - - - zinc protease
MLHCIMPN_02637 2.88e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLHCIMPN_02638 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
MLHCIMPN_02639 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
MLHCIMPN_02640 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MLHCIMPN_02641 9.58e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLHCIMPN_02642 4.64e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MLHCIMPN_02643 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLHCIMPN_02644 5.01e-275 pbpX - - V - - - Beta-lactamase
MLHCIMPN_02645 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MLHCIMPN_02646 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MLHCIMPN_02647 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MLHCIMPN_02648 8.3e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLHCIMPN_02649 7.11e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLHCIMPN_02650 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLHCIMPN_02651 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MLHCIMPN_02652 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
MLHCIMPN_02653 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLHCIMPN_02654 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLHCIMPN_02656 1.16e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MLHCIMPN_02657 1.35e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_02658 3.7e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MLHCIMPN_02659 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_02660 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MLHCIMPN_02661 3.63e-309 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MLHCIMPN_02662 5.05e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MLHCIMPN_02663 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MLHCIMPN_02664 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MLHCIMPN_02665 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02666 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MLHCIMPN_02667 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MLHCIMPN_02668 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MLHCIMPN_02669 6.55e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLHCIMPN_02670 4.27e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
MLHCIMPN_02671 4.46e-153 yoaK - - S - - - Membrane
MLHCIMPN_02672 2.78e-82 ymzB - - - - - - -
MLHCIMPN_02673 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MLHCIMPN_02674 4.29e-06 - - - - - - - -
MLHCIMPN_02675 5.4e-161 ymaC - - S - - - Replication protein
MLHCIMPN_02676 1.11e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MLHCIMPN_02677 5.05e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLHCIMPN_02678 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MLHCIMPN_02680 5.96e-77 ymaF - - S - - - YmaF family
MLHCIMPN_02681 7.32e-219 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLHCIMPN_02682 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLHCIMPN_02683 2.86e-57 - - - - - - - -
MLHCIMPN_02684 9.42e-29 ymzA - - - - - - -
MLHCIMPN_02685 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MLHCIMPN_02686 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHCIMPN_02687 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLHCIMPN_02688 2.24e-141 ymaB - - S - - - MutT family
MLHCIMPN_02689 1.86e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLHCIMPN_02690 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MLHCIMPN_02691 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLHCIMPN_02692 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLHCIMPN_02693 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MLHCIMPN_02694 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MLHCIMPN_02695 1.03e-28 - - - - - - - -
MLHCIMPN_02696 4.5e-115 - - - - - - - -
MLHCIMPN_02700 2.1e-55 - - - S - - - Protein of unknown function (DUF2568)
MLHCIMPN_02701 4.7e-51 - - - T - - - Histidine kinase
MLHCIMPN_02702 3.19e-265 mrjp - - G - - - Major royal jelly protein
MLHCIMPN_02703 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MLHCIMPN_02704 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MLHCIMPN_02705 9.04e-278 xylR - - GK - - - ROK family
MLHCIMPN_02706 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MLHCIMPN_02707 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MLHCIMPN_02708 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MLHCIMPN_02712 2.21e-27 - - - - - - - -
MLHCIMPN_02713 8.43e-73 dinB - - S - - - DinB family
MLHCIMPN_02714 8.07e-235 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MLHCIMPN_02715 3.63e-96 - - - S - - - Bacterial transferase hexapeptide (six repeats)
MLHCIMPN_02716 2.78e-24 - - - - - - - -
MLHCIMPN_02718 2.75e-39 - - - - - - - -
MLHCIMPN_02720 1.34e-94 yoaP - - K - - - YoaP-like
MLHCIMPN_02721 1.64e-77 yoaP - - K - - - YoaP-like
MLHCIMPN_02722 3.28e-128 - - - J - - - Acetyltransferase (GNAT) domain
MLHCIMPN_02723 4.55e-139 - - - S - - - Domain of unknown function (DUF3885)
MLHCIMPN_02724 6.88e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_02725 3.33e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
MLHCIMPN_02726 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MLHCIMPN_02729 0.0 yobO - - M - - - Pectate lyase superfamily protein
MLHCIMPN_02730 6.07e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MLHCIMPN_02731 1.37e-182 yndL - - S - - - Replication protein
MLHCIMPN_02732 1.74e-11 - - - - - - - -
MLHCIMPN_02733 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
MLHCIMPN_02734 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
MLHCIMPN_02736 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLHCIMPN_02737 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLHCIMPN_02738 5.22e-145 yneB - - L - - - resolvase
MLHCIMPN_02739 2.33e-43 ynzC - - S - - - UPF0291 protein
MLHCIMPN_02740 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLHCIMPN_02741 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MLHCIMPN_02742 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MLHCIMPN_02743 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
MLHCIMPN_02744 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MLHCIMPN_02745 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MLHCIMPN_02746 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MLHCIMPN_02747 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
MLHCIMPN_02748 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
MLHCIMPN_02749 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MLHCIMPN_02750 1.47e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MLHCIMPN_02751 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLHCIMPN_02752 8.17e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLHCIMPN_02754 1.73e-44 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MLHCIMPN_02755 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MLHCIMPN_02756 7.79e-70 yneQ - - - - - - -
MLHCIMPN_02757 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
MLHCIMPN_02758 2.6e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLHCIMPN_02759 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MLHCIMPN_02760 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHCIMPN_02761 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLHCIMPN_02762 5.42e-20 - - - - - - - -
MLHCIMPN_02763 1.82e-63 ynfC - - - - - - -
MLHCIMPN_02764 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MLHCIMPN_02765 1.15e-233 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
MLHCIMPN_02766 1.26e-243 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MLHCIMPN_02767 5.27e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
MLHCIMPN_02768 3.96e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MLHCIMPN_02769 5.86e-191 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_02770 2.14e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
MLHCIMPN_02771 1.07e-284 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
MLHCIMPN_02772 2e-199 yndG - - S - - - DoxX-like family
MLHCIMPN_02773 4.51e-99 - - - S - - - Domain of unknown function (DUF4166)
MLHCIMPN_02774 0.0 yndJ - - S - - - YndJ-like protein
MLHCIMPN_02775 4.6e-13 yxlH - - EGP - - - Major Facilitator Superfamily
MLHCIMPN_02777 1.44e-270 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
MLHCIMPN_02778 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
MLHCIMPN_02779 1.43e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
MLHCIMPN_02780 5.65e-311 - - - T - - - Histidine kinase
MLHCIMPN_02781 6.28e-163 - - - T - - - Transcriptional regulatory protein, C terminal
MLHCIMPN_02782 8.84e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
MLHCIMPN_02783 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MLHCIMPN_02784 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_02785 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_02786 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_02787 6.75e-288 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MLHCIMPN_02788 1.18e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLHCIMPN_02789 7.47e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLHCIMPN_02790 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLHCIMPN_02791 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
MLHCIMPN_02792 3.74e-284 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MLHCIMPN_02793 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLHCIMPN_02794 7.45e-167 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLHCIMPN_02795 3.25e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLHCIMPN_02796 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLHCIMPN_02797 8.7e-184 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLHCIMPN_02798 2.26e-95 yngA - - S - - - membrane
MLHCIMPN_02799 3.16e-144 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLHCIMPN_02800 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
MLHCIMPN_02801 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLHCIMPN_02802 1.67e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MLHCIMPN_02803 3.48e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MLHCIMPN_02804 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MLHCIMPN_02805 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MLHCIMPN_02806 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLHCIMPN_02807 1.79e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MLHCIMPN_02808 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MLHCIMPN_02809 1.96e-84 yngL - - S - - - Protein of unknown function (DUF1360)
MLHCIMPN_02810 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
MLHCIMPN_02811 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_02812 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHCIMPN_02813 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLHCIMPN_02814 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
MLHCIMPN_02815 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLHCIMPN_02816 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MLHCIMPN_02817 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLHCIMPN_02818 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLHCIMPN_02820 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLHCIMPN_02821 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLHCIMPN_02822 7.7e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MLHCIMPN_02823 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLHCIMPN_02824 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLHCIMPN_02825 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLHCIMPN_02826 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLHCIMPN_02827 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MLHCIMPN_02828 8.27e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MLHCIMPN_02829 8.14e-143 yyaC - - S - - - Sporulation protein YyaC
MLHCIMPN_02830 2.62e-105 yhhY - - K - - - FR47-like protein
MLHCIMPN_02831 4.77e-225 yyaD - - S - - - Membrane
MLHCIMPN_02832 1.82e-45 yyzM - - S - - - protein conserved in bacteria
MLHCIMPN_02833 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHCIMPN_02834 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLHCIMPN_02835 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MLHCIMPN_02836 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLHCIMPN_02837 4.51e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLHCIMPN_02838 3.63e-136 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MLHCIMPN_02839 3.38e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLHCIMPN_02840 3.29e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MLHCIMPN_02841 6.62e-230 ccpB - - K - - - Transcriptional regulator
MLHCIMPN_02842 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHCIMPN_02843 1.88e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MLHCIMPN_02844 2.84e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MLHCIMPN_02845 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MLHCIMPN_02848 4.54e-91 ynaF - - - - - - -
MLHCIMPN_02849 1.02e-106 - - - - - - - -
MLHCIMPN_02850 1.53e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MLHCIMPN_02851 6.35e-167 - - - EG - - - EamA-like transporter family
MLHCIMPN_02852 1.29e-313 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHCIMPN_02853 2.35e-176 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLHCIMPN_02854 4.21e-212 - - - K - - - Transcriptional regulator
MLHCIMPN_02855 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MLHCIMPN_02856 3.34e-211 - - - M - - - Domain of Unknown Function (DUF1259)
MLHCIMPN_02857 1.49e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
MLHCIMPN_02858 1.3e-99 yybA - - K - - - transcriptional
MLHCIMPN_02859 1.48e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_02860 2.77e-89 - - - K - - - Winged helix DNA-binding domain
MLHCIMPN_02861 1.62e-145 ydgI - - C - - - nitroreductase
MLHCIMPN_02862 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MLHCIMPN_02863 5.87e-201 - - - G - - - Major Facilitator Superfamily
MLHCIMPN_02864 2.63e-115 - - - S - - - PFAM DinB family protein
MLHCIMPN_02865 3.82e-149 - - - K - - - FCD domain
MLHCIMPN_02866 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MLHCIMPN_02867 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MLHCIMPN_02868 1.02e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLHCIMPN_02869 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MLHCIMPN_02870 4.56e-87 yybR - - K - - - Transcriptional regulator
MLHCIMPN_02871 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
MLHCIMPN_02873 1.95e-201 yybS - - S - - - membrane
MLHCIMPN_02874 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MLHCIMPN_02875 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MLHCIMPN_02876 1.7e-157 - - - KLT - - - COG0515 Serine threonine protein kinase
MLHCIMPN_02877 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
MLHCIMPN_02878 5.98e-302 - - - M - - - Glycosyltransferase Family 4
MLHCIMPN_02879 6.57e-297 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
MLHCIMPN_02880 6.38e-259 - - - S - - - Ecdysteroid kinase
MLHCIMPN_02881 1.79e-305 - - - M - - - Glycosyltransferase Family 4
MLHCIMPN_02882 5.12e-25 yycC - - K - - - YycC-like protein
MLHCIMPN_02884 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MLHCIMPN_02885 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MLHCIMPN_02886 1.57e-94 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHCIMPN_02887 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLHCIMPN_02892 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_02893 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02894 0.0 yycH - - S - - - protein conserved in bacteria
MLHCIMPN_02895 2.81e-194 yycI - - S - - - protein conserved in bacteria
MLHCIMPN_02896 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLHCIMPN_02897 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHCIMPN_02898 2.5e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_02899 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MLHCIMPN_02900 2.93e-244 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
MLHCIMPN_02901 0.0 - - - - - - - -
MLHCIMPN_02902 4.27e-257 - - - S - - - Major Facilitator Superfamily
MLHCIMPN_02903 0.0 - - - S - - - ABC transporter
MLHCIMPN_02904 6.44e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
MLHCIMPN_02905 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLHCIMPN_02906 9.38e-58 sdpR - - K - - - transcriptional
MLHCIMPN_02907 1.99e-89 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLHCIMPN_02908 1.95e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLHCIMPN_02909 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLHCIMPN_02910 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MLHCIMPN_02911 9.49e-262 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
MLHCIMPN_02913 2.92e-113 yycN - - K - - - Acetyltransferase
MLHCIMPN_02914 6.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MLHCIMPN_02915 6.82e-171 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLHCIMPN_02916 2.21e-275 yycP - - - - - - -
MLHCIMPN_02919 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLHCIMPN_02920 3.12e-116 - - - K - - - NAD+ binding
MLHCIMPN_02921 8.08e-97 - - - F - - - 5-carbamoylmethyl uridine residue modification
MLHCIMPN_02922 0.0 - - - L - - - AAA domain
MLHCIMPN_02923 5.2e-26 - - - - - - - -
MLHCIMPN_02924 9.35e-233 - - - S - - - Fusaric acid resistance protein-like
MLHCIMPN_02925 1.03e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLHCIMPN_02926 3.73e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MLHCIMPN_02927 3.46e-77 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLHCIMPN_02928 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLHCIMPN_02929 1.91e-197 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLHCIMPN_02930 4.92e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLHCIMPN_02931 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MLHCIMPN_02932 1.51e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_02933 3.95e-292 - - - S - - - Fic/DOC family
MLHCIMPN_02934 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MLHCIMPN_02935 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MLHCIMPN_02936 2.59e-160 - - - E - - - Ring-cleavage extradiol dioxygenase
MLHCIMPN_02937 7.8e-97 yxaI - - S - - - membrane protein domain
MLHCIMPN_02938 7.67e-256 - - - EGP - - - Major Facilitator Superfamily
MLHCIMPN_02939 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MLHCIMPN_02940 2.5e-85 - - - S - - - Family of unknown function (DUF5391)
MLHCIMPN_02941 1.58e-187 yxaL - - S - - - PQQ-like domain
MLHCIMPN_02942 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLHCIMPN_02943 5.42e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MLHCIMPN_02944 1.01e-254 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MLHCIMPN_02945 4.12e-255 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02946 3.72e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_02947 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MLHCIMPN_02949 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MLHCIMPN_02950 4.5e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLHCIMPN_02951 3.94e-221 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MLHCIMPN_02952 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MLHCIMPN_02953 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLHCIMPN_02954 3.45e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLHCIMPN_02955 5.42e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLHCIMPN_02956 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLHCIMPN_02957 4.62e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLHCIMPN_02958 1.23e-292 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MLHCIMPN_02959 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLHCIMPN_02960 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MLHCIMPN_02961 2.68e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLHCIMPN_02962 1.35e-202 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLHCIMPN_02963 1.05e-167 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_02964 9.21e-166 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
MLHCIMPN_02965 7.54e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_02966 1.51e-174 yvrH - - T - - - Transcriptional regulator
MLHCIMPN_02967 0.0 - - - T - - - Histidine kinase
MLHCIMPN_02968 1.09e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_02969 4.59e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_02970 6.61e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_02971 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_02972 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
MLHCIMPN_02973 1.61e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLHCIMPN_02974 2.27e-08 - - - L - - - Helix-hairpin-helix motif
MLHCIMPN_02975 6.89e-08 yxeD - - - - - - -
MLHCIMPN_02976 9.43e-34 yxeE - - - - - - -
MLHCIMPN_02979 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
MLHCIMPN_02980 1.12e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLHCIMPN_02981 1.17e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLHCIMPN_02982 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHCIMPN_02983 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MLHCIMPN_02984 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLHCIMPN_02985 1.32e-222 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLHCIMPN_02986 3.7e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MLHCIMPN_02987 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLHCIMPN_02988 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MLHCIMPN_02989 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLHCIMPN_02990 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MLHCIMPN_02992 4.36e-225 - - - L - - - AlwI restriction endonuclease
MLHCIMPN_02993 3.9e-232 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
MLHCIMPN_02994 5.59e-58 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MLHCIMPN_02995 1.86e-18 - - - S - - - Domain of unknown function (DUF5082)
MLHCIMPN_02996 5.71e-130 - - - L - - - Replication protein
MLHCIMPN_02997 4.69e-39 - - - - - - - -
MLHCIMPN_02999 7.64e-53 - - - K - - - Transcriptional regulator
MLHCIMPN_03002 1.41e-93 yxiE - - T - - - Belongs to the universal stress protein A family
MLHCIMPN_03003 8.44e-208 yxxF - - EG - - - EamA-like transporter family
MLHCIMPN_03004 1.05e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MLHCIMPN_03005 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLHCIMPN_03006 1e-279 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MLHCIMPN_03007 1.91e-183 bglS - - M - - - licheninase activity
MLHCIMPN_03008 1.35e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MLHCIMPN_03009 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLHCIMPN_03010 2.68e-67 yxiS - - - - - - -
MLHCIMPN_03011 8.8e-125 - - - T - - - Domain of unknown function (DUF4163)
MLHCIMPN_03012 9.51e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHCIMPN_03013 1.83e-163 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MLHCIMPN_03014 6.59e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MLHCIMPN_03015 6.11e-111 yxjI - - S - - - LURP-one-related
MLHCIMPN_03018 6.94e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MLHCIMPN_03019 2.28e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MLHCIMPN_03020 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
MLHCIMPN_03021 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHCIMPN_03022 2.63e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MLHCIMPN_03023 2.62e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_03024 8.1e-199 yxkH - - G - - - Polysaccharide deacetylase
MLHCIMPN_03025 3.19e-287 cimH - - C - - - COG3493 Na citrate symporter
MLHCIMPN_03026 3.05e-248 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MLHCIMPN_03027 4.4e-62 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MLHCIMPN_03028 1.12e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MLHCIMPN_03029 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MLHCIMPN_03030 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MLHCIMPN_03031 3.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLHCIMPN_03032 3.43e-77 - - - S - - - COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLHCIMPN_03033 5.75e-131 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MLHCIMPN_03034 0.00047 - - - T - - - helix_turn_helix, Lux Regulon
MLHCIMPN_03035 7.05e-24 ypdB - - KT ko:K02477,ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MLHCIMPN_03038 1.81e-127 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MLHCIMPN_03040 8.52e-314 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MLHCIMPN_03041 2.26e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MLHCIMPN_03042 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MLHCIMPN_03043 8.82e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MLHCIMPN_03044 1.58e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLHCIMPN_03045 1.27e-29 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MLHCIMPN_03046 1.93e-139 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MLHCIMPN_03047 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MLHCIMPN_03048 1.41e-302 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHCIMPN_03049 3.22e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_03050 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_03051 6.3e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLHCIMPN_03052 6.17e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MLHCIMPN_03053 7.58e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MLHCIMPN_03054 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_03055 4.69e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_03056 1.08e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MLHCIMPN_03057 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MLHCIMPN_03058 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MLHCIMPN_03059 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHCIMPN_03060 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_03061 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLHCIMPN_03062 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MLHCIMPN_03063 4.21e-287 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLHCIMPN_03064 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_03065 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MLHCIMPN_03066 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_03067 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MLHCIMPN_03068 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MLHCIMPN_03069 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MLHCIMPN_03070 3.64e-208 gspA - - M - - - General stress
MLHCIMPN_03071 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLHCIMPN_03072 2.71e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLHCIMPN_03073 1.06e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MLHCIMPN_03074 5.11e-285 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MLHCIMPN_03075 9.24e-217 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MLHCIMPN_03076 1.01e-174 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MLHCIMPN_03077 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MLHCIMPN_03078 6.47e-144 ywbG - - M - - - effector of murein hydrolase
MLHCIMPN_03079 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLHCIMPN_03080 4.83e-202 ywbI - - K - - - Transcriptional regulator
MLHCIMPN_03081 1.02e-172 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLHCIMPN_03082 5.8e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLHCIMPN_03083 5.15e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MLHCIMPN_03084 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MLHCIMPN_03085 1.58e-168 - - - S - - - Streptomycin biosynthesis protein StrF
MLHCIMPN_03086 7.2e-166 - - - H - - - Methionine biosynthesis protein MetW
MLHCIMPN_03088 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MLHCIMPN_03089 2e-80 gtcA - - S - - - GtrA-like protein
MLHCIMPN_03090 4.22e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLHCIMPN_03091 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MLHCIMPN_03092 5.74e-48 ydaS - - S - - - membrane
MLHCIMPN_03093 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLHCIMPN_03094 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLHCIMPN_03095 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MLHCIMPN_03096 6.76e-84 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MLHCIMPN_03097 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MLHCIMPN_03098 1.24e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MLHCIMPN_03099 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MLHCIMPN_03100 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MLHCIMPN_03101 1.34e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_03102 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MLHCIMPN_03104 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MLHCIMPN_03105 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MLHCIMPN_03106 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLHCIMPN_03107 3.52e-26 ywdA - - - - - - -
MLHCIMPN_03108 3.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MLHCIMPN_03109 1.32e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MLHCIMPN_03111 7.67e-85 ywdD - - - - - - -
MLHCIMPN_03113 3.29e-192 ywdF - - S - - - Glycosyltransferase like family 2
MLHCIMPN_03114 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLHCIMPN_03115 1.06e-60 ywdI - - S - - - Family of unknown function (DUF5327)
MLHCIMPN_03116 5.38e-291 ywdJ - - F - - - Xanthine uracil
MLHCIMPN_03117 2.17e-76 ywdK - - S - - - small membrane protein
MLHCIMPN_03118 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLHCIMPN_03119 5.24e-183 spsA - - M - - - Spore Coat
MLHCIMPN_03120 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MLHCIMPN_03121 3.57e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MLHCIMPN_03122 6.71e-206 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MLHCIMPN_03123 7.09e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MLHCIMPN_03124 7.11e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
MLHCIMPN_03125 5.91e-235 spsG - - M - - - Spore Coat
MLHCIMPN_03126 1.63e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLHCIMPN_03127 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLHCIMPN_03128 4.55e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLHCIMPN_03129 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MLHCIMPN_03130 1.32e-221 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_03131 1.48e-153 - - - S - - - ABC-2 family transporter protein
MLHCIMPN_03132 2.37e-96 - - - - - - - -
MLHCIMPN_03133 6.09e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_03134 2.04e-203 - - - T - - - Histidine kinase
MLHCIMPN_03135 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MLHCIMPN_03136 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLHCIMPN_03137 0.0 rocB - - E - - - arginine degradation protein
MLHCIMPN_03138 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MLHCIMPN_03139 2.43e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MLHCIMPN_03140 1.11e-283 ywfA - - EGP - - - -transporter
MLHCIMPN_03141 3.85e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLHCIMPN_03142 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLHCIMPN_03143 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_03144 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLHCIMPN_03145 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MLHCIMPN_03146 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MLHCIMPN_03147 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MLHCIMPN_03148 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MLHCIMPN_03149 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MLHCIMPN_03150 9.79e-213 - - - S - - - Conserved hypothetical protein 698
MLHCIMPN_03151 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MLHCIMPN_03152 8.76e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLHCIMPN_03154 1.51e-234 - - - - - - - -
MLHCIMPN_03157 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
MLHCIMPN_03158 1.65e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_03159 3.78e-120 - - - S - - - membrane
MLHCIMPN_03160 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
MLHCIMPN_03161 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MLHCIMPN_03162 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MLHCIMPN_03163 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MLHCIMPN_03164 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
MLHCIMPN_03165 9.94e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
MLHCIMPN_03166 4.16e-93 ywhA - - K - - - Transcriptional regulator
MLHCIMPN_03167 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MLHCIMPN_03168 3.84e-153 ywhC - - S - - - Peptidase family M50
MLHCIMPN_03169 1.92e-123 ywhD - - S - - - YwhD family
MLHCIMPN_03170 1.32e-14 - - - - - - - -
MLHCIMPN_03171 1.23e-69 - - - - - - - -
MLHCIMPN_03172 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MLHCIMPN_03173 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLHCIMPN_03174 1.73e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MLHCIMPN_03176 1.38e-103 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MLHCIMPN_03177 3.01e-294 ywhK - - CO - - - amine dehydrogenase activity
MLHCIMPN_03178 5.82e-307 ywhL - - CO - - - amine dehydrogenase activity
MLHCIMPN_03180 2.21e-94 ywiB - - S - - - protein conserved in bacteria
MLHCIMPN_03181 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MLHCIMPN_03182 4.27e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MLHCIMPN_03183 5.43e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MLHCIMPN_03184 5.69e-22 ywiC - - S - - - YwiC-like protein
MLHCIMPN_03185 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MLHCIMPN_03186 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLHCIMPN_03187 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MLHCIMPN_03188 1.48e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MLHCIMPN_03189 2.41e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MLHCIMPN_03190 3.02e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLHCIMPN_03191 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLHCIMPN_03192 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MLHCIMPN_03193 1.13e-58 ywjC - - - - - - -
MLHCIMPN_03194 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLHCIMPN_03195 6.69e-283 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLHCIMPN_03196 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MLHCIMPN_03197 8.4e-76 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLHCIMPN_03198 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLHCIMPN_03199 6.67e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
MLHCIMPN_03200 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MLHCIMPN_03201 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MLHCIMPN_03202 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLHCIMPN_03203 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHCIMPN_03204 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MLHCIMPN_03205 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLHCIMPN_03206 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MLHCIMPN_03207 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MLHCIMPN_03208 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MLHCIMPN_03209 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MLHCIMPN_03210 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLHCIMPN_03211 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLHCIMPN_03212 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLHCIMPN_03213 1.4e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLHCIMPN_03214 1.71e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MLHCIMPN_03215 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MLHCIMPN_03216 2.02e-97 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MLHCIMPN_03217 3.6e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLHCIMPN_03218 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
MLHCIMPN_03219 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLHCIMPN_03220 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MLHCIMPN_03221 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
MLHCIMPN_03222 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLHCIMPN_03223 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLHCIMPN_03224 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MLHCIMPN_03225 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MLHCIMPN_03226 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHCIMPN_03227 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLHCIMPN_03228 2.77e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLHCIMPN_03229 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLHCIMPN_03230 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLHCIMPN_03231 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLHCIMPN_03232 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MLHCIMPN_03233 4.15e-117 ywmA - - - - - - -
MLHCIMPN_03234 2.25e-45 ywzB - - S - - - membrane
MLHCIMPN_03235 8.35e-175 ywmB - - S - - - TATA-box binding
MLHCIMPN_03236 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLHCIMPN_03237 4.93e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MLHCIMPN_03238 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLHCIMPN_03239 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MLHCIMPN_03241 1.06e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLHCIMPN_03242 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLHCIMPN_03243 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MLHCIMPN_03244 3.66e-108 ywmF - - S - - - Peptidase M50
MLHCIMPN_03245 2.01e-16 csbD - - K - - - CsbD-like
MLHCIMPN_03246 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MLHCIMPN_03247 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MLHCIMPN_03248 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLHCIMPN_03249 3.61e-87 ywnA - - K - - - Transcriptional regulator
MLHCIMPN_03251 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MLHCIMPN_03252 6.88e-80 ywnC - - S - - - Family of unknown function (DUF5362)
MLHCIMPN_03253 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLHCIMPN_03254 6.01e-89 ywnF - - S - - - Family of unknown function (DUF5392)
MLHCIMPN_03256 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MLHCIMPN_03257 2.17e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MLHCIMPN_03258 4.67e-95 ywnJ - - S - - - VanZ like family
MLHCIMPN_03259 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MLHCIMPN_03260 1.72e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MLHCIMPN_03261 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MLHCIMPN_03262 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MLHCIMPN_03263 1.13e-132 yjgF - - Q - - - Isochorismatase family
MLHCIMPN_03264 2.31e-311 ywoD - - EGP - - - Major facilitator superfamily
MLHCIMPN_03265 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MLHCIMPN_03266 4.1e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_03267 3.58e-93 ywoH - - K - - - transcriptional
MLHCIMPN_03268 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MLHCIMPN_03269 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MLHCIMPN_03270 2e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MLHCIMPN_03271 4.45e-186 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MLHCIMPN_03272 1.34e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MLHCIMPN_03273 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLHCIMPN_03274 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLHCIMPN_03275 1.52e-89 ywpF - - S - - - YwpF-like protein
MLHCIMPN_03276 4.49e-82 ywpG - - - - - - -
MLHCIMPN_03277 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MLHCIMPN_03278 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MLHCIMPN_03279 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLHCIMPN_03280 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLHCIMPN_03281 0.0 ywqB - - S - - - SWIM zinc finger
MLHCIMPN_03282 1.74e-21 - - - - - - - -
MLHCIMPN_03283 8.29e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MLHCIMPN_03284 2.12e-155 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MLHCIMPN_03285 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MLHCIMPN_03286 8.72e-314 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHCIMPN_03287 1.2e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
MLHCIMPN_03290 2.97e-50 ywqI - - S - - - Family of unknown function (DUF5344)
MLHCIMPN_03291 0.0 ywqJ - - S - - - Pre-toxin TG
MLHCIMPN_03292 5.28e-113 - - - - - - - -
MLHCIMPN_03293 1.66e-65 - - - - - - - -
MLHCIMPN_03295 7.58e-123 - - - - - - - -
MLHCIMPN_03296 4.84e-170 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLHCIMPN_03297 5.92e-203 - - - K - - - Transcriptional regulator
MLHCIMPN_03298 2.58e-121 ywqN - - S - - - NAD(P)H-dependent
MLHCIMPN_03300 2.47e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MLHCIMPN_03301 2e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MLHCIMPN_03302 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MLHCIMPN_03303 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MLHCIMPN_03305 2.33e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLHCIMPN_03306 6.3e-22 - - - - - - - -
MLHCIMPN_03307 5.34e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
MLHCIMPN_03308 2.49e-183 cotB - - - ko:K06325 - ko00000 -
MLHCIMPN_03309 3.43e-163 ywrJ - - - - - - -
MLHCIMPN_03310 1.04e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLHCIMPN_03312 5.35e-215 alsR - - K - - - LysR substrate binding domain
MLHCIMPN_03313 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MLHCIMPN_03314 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MLHCIMPN_03315 1.75e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MLHCIMPN_03316 2.39e-115 batE - - T - - - Sh3 type 3 domain protein
MLHCIMPN_03317 1.15e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MLHCIMPN_03318 4.4e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLHCIMPN_03319 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLHCIMPN_03320 1.38e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLHCIMPN_03321 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLHCIMPN_03322 3.66e-229 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MLHCIMPN_03323 5.06e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
MLHCIMPN_03324 1.03e-245 - - - E - - - Spore germination protein
MLHCIMPN_03325 1.26e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
MLHCIMPN_03327 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLHCIMPN_03328 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MLHCIMPN_03329 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLHCIMPN_03330 4.04e-29 ywtC - - - - - - -
MLHCIMPN_03331 6.43e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLHCIMPN_03332 6.84e-74 yttA - - S - - - Pfam Transposase IS66
MLHCIMPN_03333 6.43e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLHCIMPN_03334 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
MLHCIMPN_03335 1.99e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLHCIMPN_03336 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
MLHCIMPN_03337 8.96e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MLHCIMPN_03338 1.66e-249 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MLHCIMPN_03339 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MLHCIMPN_03340 1.07e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MLHCIMPN_03341 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLHCIMPN_03342 2.57e-272 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLHCIMPN_03343 2.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLHCIMPN_03344 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MLHCIMPN_03345 0.0 - - - M - - - Glycosyltransferase like family 2
MLHCIMPN_03346 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLHCIMPN_03347 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MLHCIMPN_03348 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLHCIMPN_03349 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MLHCIMPN_03350 2.86e-267 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLHCIMPN_03351 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLHCIMPN_03352 1.86e-64 - - - - - - - -
MLHCIMPN_03353 0.0 lytB - - D - - - Stage II sporulation protein
MLHCIMPN_03354 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MLHCIMPN_03355 4.92e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLHCIMPN_03356 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_03357 4.87e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MLHCIMPN_03358 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHCIMPN_03359 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MLHCIMPN_03360 3.49e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MLHCIMPN_03361 4.68e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MLHCIMPN_03362 4.67e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MLHCIMPN_03363 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLHCIMPN_03364 1.16e-235 yvhJ - - K - - - Transcriptional regulator
MLHCIMPN_03365 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MLHCIMPN_03366 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLHCIMPN_03367 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_03368 1.03e-202 degV - - S - - - protein conserved in bacteria
MLHCIMPN_03369 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLHCIMPN_03370 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MLHCIMPN_03371 1.01e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MLHCIMPN_03372 5.47e-98 yvyF - - S - - - flagellar protein
MLHCIMPN_03373 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MLHCIMPN_03374 3.64e-104 yvyG - - NOU - - - FlgN protein
MLHCIMPN_03375 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MLHCIMPN_03376 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MLHCIMPN_03377 2.8e-108 yviE - - - - - - -
MLHCIMPN_03378 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLHCIMPN_03379 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLHCIMPN_03380 6.97e-153 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLHCIMPN_03381 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLHCIMPN_03382 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MLHCIMPN_03383 4.35e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MLHCIMPN_03384 1.35e-89 - - - - - - - -
MLHCIMPN_03385 2.28e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLHCIMPN_03386 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLHCIMPN_03387 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLHCIMPN_03388 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MLHCIMPN_03389 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MLHCIMPN_03390 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MLHCIMPN_03391 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLHCIMPN_03392 7.31e-306 ywoF - - P - - - Right handed beta helix region
MLHCIMPN_03393 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MLHCIMPN_03394 2.47e-73 swrA - - S - - - Swarming motility protein
MLHCIMPN_03395 7.21e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHCIMPN_03396 9.44e-240 - - - S - - - Psort location CytoplasmicMembrane, score
MLHCIMPN_03398 1.24e-33 - - - Q - - - Thioesterase domain
MLHCIMPN_03399 2.93e-298 yvkA - - P - - - -transporter
MLHCIMPN_03400 2.32e-144 yvkB - - K - - - Transcriptional regulator
MLHCIMPN_03401 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MLHCIMPN_03402 2.59e-45 csbA - - S - - - protein conserved in bacteria
MLHCIMPN_03403 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLHCIMPN_03404 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLHCIMPN_03405 3.29e-43 yvkN - - - - - - -
MLHCIMPN_03406 4.87e-66 yvlA - - - - - - -
MLHCIMPN_03407 5.54e-219 yvlB - - S - - - Putative adhesin
MLHCIMPN_03408 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MLHCIMPN_03409 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
MLHCIMPN_03410 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MLHCIMPN_03411 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MLHCIMPN_03412 2.13e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MLHCIMPN_03413 6.1e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLHCIMPN_03414 3.89e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLHCIMPN_03415 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLHCIMPN_03416 5.27e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLHCIMPN_03417 9.48e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLHCIMPN_03418 5.93e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MLHCIMPN_03419 5.06e-178 yvpB - - NU - - - protein conserved in bacteria
MLHCIMPN_03420 1.22e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLHCIMPN_03421 2.14e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLHCIMPN_03422 2.72e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLHCIMPN_03423 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MLHCIMPN_03424 9.83e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLHCIMPN_03425 2.67e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLHCIMPN_03426 8e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLHCIMPN_03427 9.88e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MLHCIMPN_03428 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MLHCIMPN_03429 3.82e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_03430 1.36e-245 sasA - - T - - - Histidine kinase
MLHCIMPN_03431 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MLHCIMPN_03432 4.64e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MLHCIMPN_03433 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLHCIMPN_03434 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLHCIMPN_03435 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MLHCIMPN_03436 1.28e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MLHCIMPN_03437 7.32e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MLHCIMPN_03438 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MLHCIMPN_03439 6.65e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MLHCIMPN_03440 5.54e-105 - - - M - - - Ribonuclease
MLHCIMPN_03441 1.69e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLHCIMPN_03442 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MLHCIMPN_03443 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MLHCIMPN_03444 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MLHCIMPN_03445 8.57e-134 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MLHCIMPN_03446 2.2e-205 yvdE - - K - - - Transcriptional regulator
MLHCIMPN_03447 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
MLHCIMPN_03448 1.49e-261 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MLHCIMPN_03449 1.1e-279 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MLHCIMPN_03450 5.29e-178 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MLHCIMPN_03451 3.08e-137 malA - - S - - - Protein of unknown function (DUF1189)
MLHCIMPN_03452 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
MLHCIMPN_03453 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLHCIMPN_03454 4.27e-120 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MLHCIMPN_03455 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLHCIMPN_03456 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
MLHCIMPN_03457 4.05e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
MLHCIMPN_03458 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MLHCIMPN_03460 1.31e-45 - - - - - - - -
MLHCIMPN_03461 0.0 - - - I - - - Pfam Lipase (class 3)
MLHCIMPN_03462 5e-22 - - - S - - - Protein of unknown function (DUF1433)
MLHCIMPN_03463 2.29e-52 - - - I - - - Pfam Lipase (class 3)
MLHCIMPN_03464 4.22e-51 - - - S - - - Protein of unknown function (DUF1433)
MLHCIMPN_03466 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MLHCIMPN_03467 1.9e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLHCIMPN_03468 4.16e-143 yyaS - - S ko:K07149 - ko00000 Membrane
MLHCIMPN_03469 2.32e-126 ywjB - - H - - - RibD C-terminal domain
MLHCIMPN_03470 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MLHCIMPN_03471 1.99e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MLHCIMPN_03472 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MLHCIMPN_03473 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MLHCIMPN_03474 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MLHCIMPN_03475 1.23e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MLHCIMPN_03476 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHCIMPN_03477 4.98e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MLHCIMPN_03478 3.44e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MLHCIMPN_03479 6.27e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MLHCIMPN_03480 2.6e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MLHCIMPN_03481 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MLHCIMPN_03482 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLHCIMPN_03483 2.73e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLHCIMPN_03484 7.66e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MLHCIMPN_03485 1.11e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MLHCIMPN_03486 2.24e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MLHCIMPN_03487 4.01e-44 yvfG - - S - - - YvfG protein
MLHCIMPN_03488 2.67e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLHCIMPN_03489 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MLHCIMPN_03490 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MLHCIMPN_03491 3.57e-281 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLHCIMPN_03492 3.55e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLHCIMPN_03493 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLHCIMPN_03494 1.44e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLHCIMPN_03496 2.49e-07 - - - S ko:K07483 - ko00000 leucine-zipper of insertion element IS481
MLHCIMPN_03497 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MLHCIMPN_03498 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MLHCIMPN_03499 1.9e-195 gntR - - K - - - RpiR family transcriptional regulator
MLHCIMPN_03500 1.79e-214 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MLHCIMPN_03501 2.47e-146 - - - S ko:K07149 - ko00000 Membrane
MLHCIMPN_03502 1.51e-232 yhjM - - K - - - Transcriptional regulator
MLHCIMPN_03503 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MLHCIMPN_03504 6.36e-204 yvbV - - EG - - - EamA-like transporter family
MLHCIMPN_03505 1.24e-199 yvbU - - K - - - Transcriptional regulator
MLHCIMPN_03507 1.08e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_03508 4.51e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MLHCIMPN_03509 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MLHCIMPN_03511 3.44e-239 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLHCIMPN_03512 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLHCIMPN_03513 6.6e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MLHCIMPN_03514 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLHCIMPN_03515 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MLHCIMPN_03516 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLHCIMPN_03517 1.63e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MLHCIMPN_03518 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLHCIMPN_03519 1.83e-277 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MLHCIMPN_03520 2.36e-217 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MLHCIMPN_03521 8.99e-293 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLHCIMPN_03522 2.95e-187 - - - M - - - Protein involved in cellulose biosynthesis
MLHCIMPN_03523 2.89e-185 - - - C - - - WbqC-like protein family
MLHCIMPN_03524 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
MLHCIMPN_03525 4.84e-229 - - - - - - - -
MLHCIMPN_03526 2.56e-268 - - - EGP - - - Major facilitator Superfamily
MLHCIMPN_03527 1.29e-105 yvbK - - K - - - acetyltransferase
MLHCIMPN_03528 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MLHCIMPN_03529 7.3e-155 yvbI - - M - - - Membrane
MLHCIMPN_03530 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MLHCIMPN_03531 6.82e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MLHCIMPN_03532 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLHCIMPN_03533 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHCIMPN_03534 4.61e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHCIMPN_03535 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHCIMPN_03536 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MLHCIMPN_03537 1.66e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLHCIMPN_03538 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHCIMPN_03539 1.8e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLHCIMPN_03540 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MLHCIMPN_03541 1.55e-161 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_03542 1.15e-155 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_03543 6.04e-173 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MLHCIMPN_03544 1.34e-158 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MLHCIMPN_03545 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MLHCIMPN_03546 2.44e-69 yvaP - - K - - - transcriptional
MLHCIMPN_03547 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MLHCIMPN_03548 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MLHCIMPN_03549 1.64e-47 yvzC - - K - - - transcriptional
MLHCIMPN_03550 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MLHCIMPN_03551 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MLHCIMPN_03552 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLHCIMPN_03553 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLHCIMPN_03555 1.06e-39 - - - S - - - Phage integrase family
MLHCIMPN_03558 1.88e-06 - - - L - - - AAA ATPase domain
MLHCIMPN_03560 1.13e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03561 3.82e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
MLHCIMPN_03562 3.69e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MLHCIMPN_03563 5.65e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MLHCIMPN_03564 2.91e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MLHCIMPN_03565 7.29e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHCIMPN_03566 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHCIMPN_03567 8.64e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MLHCIMPN_03568 3.54e-232 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_03569 3.52e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
MLHCIMPN_03570 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLHCIMPN_03571 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLHCIMPN_03572 9.62e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MLHCIMPN_03573 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MLHCIMPN_03574 1.88e-39 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
MLHCIMPN_03575 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MLHCIMPN_03576 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MLHCIMPN_03577 1.84e-137 bdbD - - O - - - Thioredoxin
MLHCIMPN_03578 3.05e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MLHCIMPN_03579 1.1e-189 - - - S - - - Metallo-peptidase family M12
MLHCIMPN_03580 1.3e-138 yvgT - - S - - - membrane
MLHCIMPN_03581 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MLHCIMPN_03582 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLHCIMPN_03583 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLHCIMPN_03584 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MLHCIMPN_03585 1.32e-111 yvgO - - - - - - -
MLHCIMPN_03586 7.23e-200 yvgN - - S - - - reductase
MLHCIMPN_03587 5.2e-255 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MLHCIMPN_03588 1.22e-249 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MLHCIMPN_03589 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MLHCIMPN_03590 7.24e-245 - - - T - - - Histidine kinase
MLHCIMPN_03591 4.32e-148 yfiK - - K - - - Regulator
MLHCIMPN_03592 2.33e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MLHCIMPN_03593 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MLHCIMPN_03594 3.88e-211 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MLHCIMPN_03595 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MLHCIMPN_03596 4.11e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MLHCIMPN_03597 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MLHCIMPN_03598 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MLHCIMPN_03599 1.28e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MLHCIMPN_03600 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_03601 2.27e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_03602 1.39e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHCIMPN_03603 8.36e-89 yvrL - - S - - - Regulatory protein YrvL
MLHCIMPN_03604 8.91e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MLHCIMPN_03605 1.88e-21 - - - S - - - YvrJ protein family
MLHCIMPN_03606 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MLHCIMPN_03607 1.67e-50 - - - - - - - -
MLHCIMPN_03608 7.74e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_03609 0.0 yvrG - - T - - - Histidine kinase
MLHCIMPN_03610 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MLHCIMPN_03611 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03612 1.93e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MLHCIMPN_03613 7.3e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLHCIMPN_03614 3.18e-281 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLHCIMPN_03615 1.54e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MLHCIMPN_03616 2.77e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_03617 3.14e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MLHCIMPN_03618 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLHCIMPN_03619 1.43e-192 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MLHCIMPN_03620 2.99e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MLHCIMPN_03621 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_03622 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_03623 2.93e-260 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MLHCIMPN_03624 2.16e-244 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MLHCIMPN_03625 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MLHCIMPN_03626 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
MLHCIMPN_03627 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLHCIMPN_03628 1.8e-200 yuxN - - K - - - Transcriptional regulator
MLHCIMPN_03629 2.68e-32 - - - - - - - -
MLHCIMPN_03630 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_03631 3.7e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLHCIMPN_03632 1.26e-303 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLHCIMPN_03633 2.39e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MLHCIMPN_03634 1.29e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03635 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MLHCIMPN_03636 7.61e-60 - - - S - - - YusW-like protein
MLHCIMPN_03637 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MLHCIMPN_03638 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
MLHCIMPN_03639 2.83e-239 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLHCIMPN_03640 4.14e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MLHCIMPN_03641 2.31e-201 - - - K - - - Transcriptional regulator
MLHCIMPN_03642 4.52e-202 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MLHCIMPN_03643 1.81e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03644 1.24e-86 yusQ - - S - - - Tautomerase enzyme
MLHCIMPN_03645 0.0 yusP - - P - - - Major facilitator superfamily
MLHCIMPN_03646 1.31e-89 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MLHCIMPN_03647 5.21e-71 yusN - - M - - - Coat F domain
MLHCIMPN_03648 3.2e-58 - - - - - - - -
MLHCIMPN_03649 8.5e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MLHCIMPN_03650 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MLHCIMPN_03651 1.56e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MLHCIMPN_03652 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MLHCIMPN_03653 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MLHCIMPN_03654 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLHCIMPN_03655 1.8e-54 yusG - - S - - - Protein of unknown function (DUF2553)
MLHCIMPN_03656 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MLHCIMPN_03657 1.64e-72 yusE - - CO - - - Thioredoxin
MLHCIMPN_03658 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
MLHCIMPN_03659 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLHCIMPN_03660 1.91e-134 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MLHCIMPN_03661 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MLHCIMPN_03662 5.13e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLHCIMPN_03663 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLHCIMPN_03664 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MLHCIMPN_03665 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLHCIMPN_03666 5.15e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MLHCIMPN_03667 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MLHCIMPN_03668 2.94e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLHCIMPN_03669 6.17e-104 yncE - - S - - - Protein of unknown function (DUF2691)
MLHCIMPN_03671 1.16e-48 - - - - - - - -
MLHCIMPN_03672 2.72e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MLHCIMPN_03673 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MLHCIMPN_03675 1.75e-28 - - - S - - - Sporulation delaying protein SdpA
MLHCIMPN_03676 4.36e-94 - - - - - - - -
MLHCIMPN_03678 2.73e-211 - - - K - - - helix_turn_helix, mercury resistance
MLHCIMPN_03679 1.57e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLHCIMPN_03680 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MLHCIMPN_03681 1.68e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MLHCIMPN_03682 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MLHCIMPN_03683 2.16e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MLHCIMPN_03684 4.84e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MLHCIMPN_03685 4.53e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MLHCIMPN_03686 4.09e-217 bsn - - L - - - Ribonuclease
MLHCIMPN_03687 9.02e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLHCIMPN_03688 2.32e-299 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLHCIMPN_03689 4.28e-274 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MLHCIMPN_03690 3.55e-30 - - - - - - - -
MLHCIMPN_03691 2.77e-12 - - - - - - - -
MLHCIMPN_03693 8.78e-18 yqbD - - L - - - Putative phage serine protease XkdF
MLHCIMPN_03694 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MLHCIMPN_03695 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLHCIMPN_03696 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
MLHCIMPN_03697 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
MLHCIMPN_03698 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MLHCIMPN_03699 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MLHCIMPN_03700 2.75e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MLHCIMPN_03701 8.24e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MLHCIMPN_03702 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLHCIMPN_03703 3.71e-62 yutD - - S - - - protein conserved in bacteria
MLHCIMPN_03704 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
MLHCIMPN_03705 1.38e-178 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLHCIMPN_03706 1.75e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MLHCIMPN_03707 1.55e-250 yutH - - S - - - Spore coat protein
MLHCIMPN_03708 8.26e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MLHCIMPN_03709 5.41e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLHCIMPN_03710 6.76e-217 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLHCIMPN_03711 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MLHCIMPN_03712 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MLHCIMPN_03713 1.34e-72 yuzD - - S - - - protein conserved in bacteria
MLHCIMPN_03714 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLHCIMPN_03715 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
MLHCIMPN_03716 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLHCIMPN_03717 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLHCIMPN_03718 3.25e-81 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MLHCIMPN_03719 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03720 4.15e-122 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MLHCIMPN_03722 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
MLHCIMPN_03724 6.54e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MLHCIMPN_03725 5.92e-93 - - - CP - - - Membrane
MLHCIMPN_03726 2.32e-39 - - - - - - - -
MLHCIMPN_03727 1.35e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLHCIMPN_03729 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MLHCIMPN_03730 3.42e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MLHCIMPN_03731 2.45e-45 yuiB - - S - - - Putative membrane protein
MLHCIMPN_03732 9.86e-153 yuiC - - S - - - protein conserved in bacteria
MLHCIMPN_03733 8.29e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MLHCIMPN_03734 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLHCIMPN_03735 8.19e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MLHCIMPN_03736 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MLHCIMPN_03737 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MLHCIMPN_03738 1.72e-209 eSD - - S ko:K07017 - ko00000 Putative esterase
MLHCIMPN_03739 2.03e-170 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MLHCIMPN_03740 3.2e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MLHCIMPN_03741 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MLHCIMPN_03742 7.94e-220 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MLHCIMPN_03743 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLHCIMPN_03744 9.15e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MLHCIMPN_03745 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MLHCIMPN_03746 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MLHCIMPN_03747 1.22e-290 yukF - - QT - - - Transcriptional regulator
MLHCIMPN_03748 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
MLHCIMPN_03749 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MLHCIMPN_03750 6.52e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MLHCIMPN_03751 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLHCIMPN_03752 0.0 yueB - - S - - - type VII secretion protein EsaA
MLHCIMPN_03753 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
MLHCIMPN_03754 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLHCIMPN_03755 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MLHCIMPN_03756 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
MLHCIMPN_03757 2.67e-238 yueF - - S - - - transporter activity
MLHCIMPN_03758 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MLHCIMPN_03759 5.46e-51 yueH - - S - - - YueH-like protein
MLHCIMPN_03760 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
MLHCIMPN_03761 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MLHCIMPN_03762 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLHCIMPN_03763 5.64e-295 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MLHCIMPN_03764 4.23e-67 yuzC - - - - - - -
MLHCIMPN_03766 2.66e-11 - - - S - - - DegQ (SacQ) family
MLHCIMPN_03767 6.21e-190 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
MLHCIMPN_03769 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_03770 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLHCIMPN_03771 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MLHCIMPN_03772 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MLHCIMPN_03773 5.47e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHCIMPN_03774 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHCIMPN_03775 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHCIMPN_03776 8.54e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHCIMPN_03777 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLHCIMPN_03778 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLHCIMPN_03780 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLHCIMPN_03781 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MLHCIMPN_03782 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MLHCIMPN_03783 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MLHCIMPN_03784 6.58e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MLHCIMPN_03785 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MLHCIMPN_03786 9.25e-101 yufK - - S - - - Family of unknown function (DUF5366)
MLHCIMPN_03787 5.29e-95 yuxK - - S - - - protein conserved in bacteria
MLHCIMPN_03788 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MLHCIMPN_03789 3.4e-259 yuxJ - - EGP - - - Major facilitator superfamily
MLHCIMPN_03790 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MLHCIMPN_03791 2.81e-88 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MLHCIMPN_03792 2.88e-289 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MLHCIMPN_03793 1.92e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLHCIMPN_03794 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
MLHCIMPN_03795 1.64e-199 yugF - - I - - - Hydrolase
MLHCIMPN_03796 3.75e-109 alaR - - K - - - Transcriptional regulator
MLHCIMPN_03797 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MLHCIMPN_03798 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MLHCIMPN_03799 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MLHCIMPN_03800 2.24e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLHCIMPN_03801 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MLHCIMPN_03802 4.34e-152 ycaC - - Q - - - Isochorismatase family
MLHCIMPN_03803 1.32e-131 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MLHCIMPN_03804 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MLHCIMPN_03806 8.53e-95 yugN - - S - - - YugN-like family
MLHCIMPN_03807 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MLHCIMPN_03808 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
MLHCIMPN_03809 2.16e-23 - - - - - - - -
MLHCIMPN_03810 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MLHCIMPN_03811 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MLHCIMPN_03812 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MLHCIMPN_03813 7.72e-98 yugU - - S - - - Uncharacterised protein family UPF0047
MLHCIMPN_03814 2.01e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLHCIMPN_03815 6.59e-55 - - - - - - - -
MLHCIMPN_03816 2.22e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MLHCIMPN_03817 1.32e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLHCIMPN_03818 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLHCIMPN_03819 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLHCIMPN_03820 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MLHCIMPN_03821 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MLHCIMPN_03822 1.29e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MLHCIMPN_03823 9.96e-251 yubA - - S - - - transporter activity
MLHCIMPN_03824 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLHCIMPN_03826 4.37e-68 yjcN - - - - - - -
MLHCIMPN_03827 3.73e-157 - - - G - - - Cupin
MLHCIMPN_03828 1.07e-280 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLHCIMPN_03829 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLHCIMPN_03830 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MLHCIMPN_03831 9.28e-121 yuaB - - - - - - -
MLHCIMPN_03832 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MLHCIMPN_03833 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MLHCIMPN_03834 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MLHCIMPN_03835 6.79e-141 - - - S - - - MOSC domain
MLHCIMPN_03836 2.98e-104 yuaE - - S - - - DinB superfamily
MLHCIMPN_03837 5.61e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MLHCIMPN_03838 1.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MLHCIMPN_03839 6.67e-123 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)