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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IHEPNEOK_00001	5.43e-97	-	-	-	-	-	-	-	-
IHEPNEOK_00003	1.1e-35	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity
IHEPNEOK_00005	1.1e-35	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	beta-glucosidase activity
IHEPNEOK_00006	5.53e-243	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IHEPNEOK_00007	3.6e-38	scrK	2.7.1.2, 2.7.1.4	-	GK	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
IHEPNEOK_00009	2.91e-179	-	-	-	-	-	-	-	-
IHEPNEOK_00011	1.81e-109	-	-	-	K	-	-	-	DNA-templated transcription, initiation
IHEPNEOK_00012	2.5e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IHEPNEOK_00013	1.46e-212	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
IHEPNEOK_00014	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IHEPNEOK_00015	6.42e-229	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
IHEPNEOK_00016	1.64e-120	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
IHEPNEOK_00017	1.02e-195	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
IHEPNEOK_00018	1.62e-133	-	-	-	T	-	-	-	EAL domain
IHEPNEOK_00019	1.86e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IHEPNEOK_00020	1.92e-161	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
IHEPNEOK_00021	4.69e-17	-	-	-	-	-	-	-	-
IHEPNEOK_00022	2.85e-153	-	-	-	-	-	-	-	-
IHEPNEOK_00023	8.4e-56	-	-	-	-	-	-	-	-
IHEPNEOK_00024	2.66e-114	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin transmembrane transporter activity
IHEPNEOK_00025	3.57e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IHEPNEOK_00026	9.71e-24	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
IHEPNEOK_00027	5.13e-77	-	-	-	S	-	-	-	glycolate biosynthetic process
IHEPNEOK_00028	5.32e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IHEPNEOK_00029	3.81e-105	-	-	-	-	-	-	-	-
IHEPNEOK_00030	2.11e-221	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
IHEPNEOK_00031	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
IHEPNEOK_00032	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
IHEPNEOK_00034	5.84e-123	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
IHEPNEOK_00035	3.37e-129	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
IHEPNEOK_00036	7.25e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_00037	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHEPNEOK_00038	1.74e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHEPNEOK_00039	1.56e-182	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IHEPNEOK_00040	2.13e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHEPNEOK_00041	3.72e-194	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHEPNEOK_00042	6.41e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHEPNEOK_00043	1.39e-17	-	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249,ko:K18244	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
IHEPNEOK_00044	1.8e-76	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_00045	4.87e-127	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_00046	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_00047	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHEPNEOK_00048	1.06e-166	-	-	-	-	-	-	-	-
IHEPNEOK_00049	2.34e-207	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
IHEPNEOK_00050	1.5e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
IHEPNEOK_00051	8.44e-138	-	-	-	-	-	-	-	-
IHEPNEOK_00053	2.66e-220	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IHEPNEOK_00054	4.37e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IHEPNEOK_00055	1.58e-281	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
IHEPNEOK_00056	3.15e-126	-	-	-	S	-	-	-	Membrane
IHEPNEOK_00057	3.39e-190	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHEPNEOK_00058	7.08e-221	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
IHEPNEOK_00059	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00060	2.27e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
IHEPNEOK_00061	7.03e-151	-	-	-	M	-	-	-	Glycosyl transferase family 8
IHEPNEOK_00062	1.25e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
IHEPNEOK_00063	2.73e-195	-	-	-	I	-	-	-	Acyl-transferase
IHEPNEOK_00065	3.27e-170	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IHEPNEOK_00066	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHEPNEOK_00067	0.0	yycH	-	-	S	-	-	-	YycH protein
IHEPNEOK_00068	3.25e-182	yycI	-	-	S	-	-	-	YycH protein
IHEPNEOK_00069	6.41e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
IHEPNEOK_00070	1.29e-239	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
IHEPNEOK_00071	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHEPNEOK_00075	5.35e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IHEPNEOK_00076	5.34e-42	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHEPNEOK_00077	1.11e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHEPNEOK_00078	4.27e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IHEPNEOK_00079	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00080	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_00081	6.12e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IHEPNEOK_00082	4.6e-220	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_00083	2.22e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IHEPNEOK_00084	3.96e-177	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IHEPNEOK_00086	4.84e-284	-	-	-	S	ko:K09136	-	ko00000,ko03009	ATP diphosphatase activity
IHEPNEOK_00087	3.42e-195	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IHEPNEOK_00088	5.3e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IHEPNEOK_00089	1.67e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
IHEPNEOK_00090	6.46e-265	ysdE	-	-	P	-	-	-	Citrate transporter
IHEPNEOK_00091	2.02e-23	-	-	-	-	-	-	-	-
IHEPNEOK_00092	1.32e-220	-	-	-	L	-	-	-	HNH nucleases
IHEPNEOK_00093	4.91e-154	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHEPNEOK_00094	2.81e-181	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00095	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00096	6.22e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IHEPNEOK_00097	7.87e-88	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
IHEPNEOK_00098	2.5e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
IHEPNEOK_00099	1.43e-105	-	-	-	-	-	-	-	-
IHEPNEOK_00100	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHEPNEOK_00101	4.47e-229	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IHEPNEOK_00102	1.18e-174	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHEPNEOK_00103	2.81e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IHEPNEOK_00104	8.17e-205	epsV	-	-	S	-	-	-	glycosyl transferase family 2
IHEPNEOK_00105	1.11e-161	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IHEPNEOK_00106	2.95e-237	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHEPNEOK_00107	7.44e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHEPNEOK_00108	3.93e-184	-	-	-	-	-	-	-	-
IHEPNEOK_00109	4.16e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
IHEPNEOK_00110	6.52e-266	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
IHEPNEOK_00111	4.03e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IHEPNEOK_00113	5.27e-242	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
IHEPNEOK_00114	2.81e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
IHEPNEOK_00115	3.11e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IHEPNEOK_00116	1.74e-23	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IHEPNEOK_00117	1.99e-68	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
IHEPNEOK_00118	2.03e-127	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHEPNEOK_00119	2.17e-185	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00120	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
IHEPNEOK_00121	6.17e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHEPNEOK_00122	2.59e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
IHEPNEOK_00123	1.28e-108	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IHEPNEOK_00124	3.05e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHEPNEOK_00125	3.83e-109	usp5	-	-	T	-	-	-	universal stress protein
IHEPNEOK_00126	4.89e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
IHEPNEOK_00127	2.39e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IHEPNEOK_00128	9.17e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHEPNEOK_00129	9.06e-191	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHEPNEOK_00130	1.08e-263	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00131	8.88e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00132	3e-108	-	-	-	-	-	-	-	-
IHEPNEOK_00133	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHEPNEOK_00134	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IHEPNEOK_00135	5.46e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IHEPNEOK_00136	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
IHEPNEOK_00137	7.21e-182	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHEPNEOK_00138	1.61e-44	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
IHEPNEOK_00139	7.92e-61	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
IHEPNEOK_00140	5.83e-292	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHEPNEOK_00141	2.18e-82	-	-	-	O	-	-	-	Glutaredoxin-related protein
IHEPNEOK_00142	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IHEPNEOK_00143	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
IHEPNEOK_00144	2.42e-96	-	-	-	-	-	-	-	-
IHEPNEOK_00145	3.1e-177	-	-	-	-	-	-	-	-
IHEPNEOK_00146	1.23e-39	-	-	-	-	-	-	-	-
IHEPNEOK_00147	6.35e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
IHEPNEOK_00148	2.8e-260	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHEPNEOK_00149	0.0	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
IHEPNEOK_00150	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
IHEPNEOK_00151	7.04e-124	-	-	-	S	-	-	-	Oxidoreductase
IHEPNEOK_00152	2.38e-171	-	-	-	-	-	-	-	-
IHEPNEOK_00153	2.71e-167	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHEPNEOK_00154	9.16e-272	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_00155	1.2e-140	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHEPNEOK_00156	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
IHEPNEOK_00157	1.68e-70	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
IHEPNEOK_00158	2.03e-44	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_00159	1.1e-59	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_00160	4.67e-127	-	3.6.1.67	-	F	ko:K19965	ko00790,map00790	ko00000,ko00001,ko00002,ko01000	NUDIX domain
IHEPNEOK_00161	1.32e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
IHEPNEOK_00162	1.21e-81	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00163	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00164	2.53e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_00167	3.23e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHEPNEOK_00169	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
IHEPNEOK_00170	2.08e-116	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IHEPNEOK_00171	1.33e-296	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
IHEPNEOK_00172	8.02e-54	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IHEPNEOK_00173	1.27e-311	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IHEPNEOK_00174	4.51e-155	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHEPNEOK_00175	9.42e-30	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00176	1.76e-77	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00177	1.49e-220	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00178	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00179	5.19e-42	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHEPNEOK_00180	4.15e-160	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00181	1.1e-126	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00182	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00183	9.35e-202	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHEPNEOK_00184	3.19e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHEPNEOK_00185	2.78e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHEPNEOK_00186	1.33e-227	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHEPNEOK_00187	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
IHEPNEOK_00188	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
IHEPNEOK_00189	6.11e-96	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IHEPNEOK_00190	5.07e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHEPNEOK_00191	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHEPNEOK_00192	4.21e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHEPNEOK_00193	1.31e-182	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IHEPNEOK_00194	2.6e-121	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
IHEPNEOK_00195	9.99e-81	-	-	-	-	-	-	-	-
IHEPNEOK_00196	3.79e-291	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
IHEPNEOK_00197	2.76e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHEPNEOK_00198	4.88e-262	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHEPNEOK_00199	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IHEPNEOK_00200	5.02e-52	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
IHEPNEOK_00201	7.29e-84	-	-	-	S	-	-	-	HicB family
IHEPNEOK_00202	7.71e-294	-	-	-	KLT	-	-	-	Protein kinase domain
IHEPNEOK_00203	3.09e-210	-	-	-	KLT	-	-	-	Protein kinase domain
IHEPNEOK_00204	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_00205	2.63e-182	-	-	-	K	-	-	-	Transcriptional regulator
IHEPNEOK_00206	4.16e-305	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IHEPNEOK_00211	4.74e-177	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IHEPNEOK_00212	6.82e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00213	2.37e-93	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00214	4.18e-55	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00216	7.71e-165	-	-	-	F	-	-	-	Phosphorylase superfamily
IHEPNEOK_00217	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
IHEPNEOK_00218	2.96e-217	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IHEPNEOK_00219	9.96e-25	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IHEPNEOK_00220	4.33e-200	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IHEPNEOK_00221	4.11e-223	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
IHEPNEOK_00222	1.26e-101	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IHEPNEOK_00223	5.71e-08	tyrA	1.3.1.12, 5.4.99.5	-	E	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
IHEPNEOK_00224	2.44e-99	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IHEPNEOK_00225	2.51e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
IHEPNEOK_00226	1.28e-61	-	-	-	Q	-	-	-	phosphatase activity
IHEPNEOK_00227	6.99e-120	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_00228	8.99e-104	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHEPNEOK_00229	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHEPNEOK_00230	6.41e-25	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
IHEPNEOK_00231	4.64e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
IHEPNEOK_00232	3.86e-49	-	-	-	-	-	-	-	-
IHEPNEOK_00233	3.04e-81	-	-	-	-	-	-	-	-
IHEPNEOK_00234	1.9e-56	-	-	-	L	-	-	-	Membrane
IHEPNEOK_00235	2.32e-187	-	-	-	F	-	-	-	NUDIX domain
IHEPNEOK_00236	0.0	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_00237	3.88e-55	-	-	-	S	-	-	-	Enterocin A Immunity
IHEPNEOK_00239	3.2e-150	-	-	-	E	-	-	-	peptidase
IHEPNEOK_00240	5.53e-174	-	-	-	V	-	-	-	ABC-2 type transporter
IHEPNEOK_00241	5.66e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IHEPNEOK_00242	2.52e-51	-	-	-	S	-	-	-	Aromatic-ring-opening dioxygenase LigAB, LigA subunit
IHEPNEOK_00243	4.12e-07	-	-	-	KLT	-	-	-	Protein tyrosine kinase
IHEPNEOK_00244	8.36e-154	-	-	-	-	-	-	-	-
IHEPNEOK_00246	9.25e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IHEPNEOK_00247	2.79e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
IHEPNEOK_00248	5.02e-134	-	-	-	S	ko:K06872	-	ko00000	TPM domain
IHEPNEOK_00249	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
IHEPNEOK_00250	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHEPNEOK_00251	1.57e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
IHEPNEOK_00252	3.34e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHEPNEOK_00253	6.4e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHEPNEOK_00254	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
IHEPNEOK_00255	4.31e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IHEPNEOK_00256	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHEPNEOK_00257	3.49e-61	-	-	-	-	-	-	-	-
IHEPNEOK_00258	1.27e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHEPNEOK_00259	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHEPNEOK_00260	1.73e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
IHEPNEOK_00261	3.45e-91	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHEPNEOK_00262	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHEPNEOK_00263	6e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHEPNEOK_00264	3.27e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IHEPNEOK_00265	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHEPNEOK_00266	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHEPNEOK_00267	3.58e-93	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHEPNEOK_00268	5.64e-277	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHEPNEOK_00269	9.02e-163	-	-	-	S	-	-	-	(CBS) domain
IHEPNEOK_00270	5.2e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHEPNEOK_00271	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHEPNEOK_00272	1.48e-45	yabO	-	-	J	-	-	-	S4 domain protein
IHEPNEOK_00273	4.01e-78	-	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IHEPNEOK_00274	4.32e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
IHEPNEOK_00275	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHEPNEOK_00276	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHEPNEOK_00277	2.85e-210	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHEPNEOK_00278	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00279	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IHEPNEOK_00280	1.09e-251	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHEPNEOK_00281	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IHEPNEOK_00283	1.56e-177	-	-	-	T	ko:K03320	-	ko00000,ko02000	GGDEF domain
IHEPNEOK_00285	4.18e-31	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
IHEPNEOK_00286	8.72e-279	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IHEPNEOK_00287	2.24e-139	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
IHEPNEOK_00291	3.71e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IHEPNEOK_00292	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IHEPNEOK_00295	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHEPNEOK_00296	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHEPNEOK_00298	1.83e-09	-	-	-	S	-	-	-	hydrolase
IHEPNEOK_00299	3.01e-11	-	-	-	Q	-	-	-	phosphatase activity
IHEPNEOK_00300	2.96e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHEPNEOK_00301	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHEPNEOK_00302	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHEPNEOK_00303	1.55e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IHEPNEOK_00304	3.42e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHEPNEOK_00305	6.65e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IHEPNEOK_00306	1.72e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHEPNEOK_00307	2.82e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHEPNEOK_00308	1.79e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHEPNEOK_00309	3.7e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHEPNEOK_00310	2.31e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHEPNEOK_00311	8.89e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHEPNEOK_00312	9.34e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IHEPNEOK_00313	1.34e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHEPNEOK_00314	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHEPNEOK_00315	1.38e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHEPNEOK_00316	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHEPNEOK_00317	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHEPNEOK_00318	2.92e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHEPNEOK_00319	1.55e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHEPNEOK_00320	4.52e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHEPNEOK_00321	1.1e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IHEPNEOK_00322	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IHEPNEOK_00323	5.33e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHEPNEOK_00324	3.43e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHEPNEOK_00325	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHEPNEOK_00326	5.08e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHEPNEOK_00327	6.6e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHEPNEOK_00328	1.18e-211	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHEPNEOK_00329	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IHEPNEOK_00330	5.7e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHEPNEOK_00331	2.44e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHEPNEOK_00332	1.28e-183	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHEPNEOK_00333	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHEPNEOK_00334	1.54e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHEPNEOK_00335	9.68e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IHEPNEOK_00336	1.79e-30	-	-	-	-	-	-	-	-
IHEPNEOK_00337	5.07e-61	-	-	-	-	-	-	-	-
IHEPNEOK_00338	6.38e-236	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00339	6.56e-16	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00340	3.47e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IHEPNEOK_00341	4.19e-64	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_00342	3.32e-63	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_00343	1.8e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
IHEPNEOK_00346	4.22e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHEPNEOK_00347	3.07e-225	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IHEPNEOK_00350	1.27e-73	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00351	6.54e-273	-	-	-	-	-	-	-	-
IHEPNEOK_00352	8.02e-255	-	-	-	-	-	-	-	-
IHEPNEOK_00353	2.79e-162	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
IHEPNEOK_00354	2.52e-286	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IHEPNEOK_00355	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IHEPNEOK_00356	1.19e-173	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IHEPNEOK_00357	1.51e-260	-	-	-	M	-	-	-	Glycosyl transferases group 1
IHEPNEOK_00358	1.77e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
IHEPNEOK_00359	3.16e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHEPNEOK_00360	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
IHEPNEOK_00363	2.97e-143	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_00364	2.99e-119	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IHEPNEOK_00366	5.61e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHEPNEOK_00367	1.75e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
IHEPNEOK_00368	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IHEPNEOK_00369	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHEPNEOK_00370	8.06e-259	camS	-	-	S	-	-	-	sex pheromone
IHEPNEOK_00371	3.99e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHEPNEOK_00372	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHEPNEOK_00373	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHEPNEOK_00374	5.36e-218	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
IHEPNEOK_00375	2.18e-158	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IHEPNEOK_00376	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHEPNEOK_00377	1.92e-204	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
IHEPNEOK_00378	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
IHEPNEOK_00379	1.17e-66	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHEPNEOK_00380	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
IHEPNEOK_00381	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
IHEPNEOK_00382	2.06e-62	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IHEPNEOK_00383	2.45e-129	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
IHEPNEOK_00384	1.79e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IHEPNEOK_00385	1.15e-159	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
IHEPNEOK_00386	5.77e-123	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
IHEPNEOK_00387	1.52e-98	-	-	-	T	-	-	-	Gaf domain
IHEPNEOK_00388	2.85e-11	-	-	-	T	-	-	-	GGDEF domain
IHEPNEOK_00390	1.17e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IHEPNEOK_00391	2.21e-69	-	-	-	S	ko:K08987	-	ko00000	membrane
IHEPNEOK_00392	3.25e-112	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
IHEPNEOK_00393	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHEPNEOK_00394	2.29e-70	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
IHEPNEOK_00395	4.6e-10	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IHEPNEOK_00396	2.28e-44	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol metabolic process
IHEPNEOK_00397	1.22e-48	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
IHEPNEOK_00398	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHEPNEOK_00399	2.74e-214	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IHEPNEOK_00400	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IHEPNEOK_00401	4.47e-129	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IHEPNEOK_00402	2.32e-64	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
IHEPNEOK_00404	1.54e-75	-	-	-	-	-	-	-	-
IHEPNEOK_00405	2.39e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
IHEPNEOK_00406	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IHEPNEOK_00407	9.39e-184	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IHEPNEOK_00408	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_00409	9.54e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
IHEPNEOK_00410	7.06e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IHEPNEOK_00412	5.48e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
IHEPNEOK_00413	1.57e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
IHEPNEOK_00414	1.62e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00415	1.14e-193	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_00416	9.37e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00417	3.22e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00418	1.24e-198	-	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
IHEPNEOK_00419	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
IHEPNEOK_00420	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IHEPNEOK_00421	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
IHEPNEOK_00423	1.6e-114	-	-	-	-	-	-	-	-
IHEPNEOK_00424	7.49e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHEPNEOK_00425	1.29e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IHEPNEOK_00426	6.1e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHEPNEOK_00427	3.12e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
IHEPNEOK_00428	2.21e-167	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
IHEPNEOK_00429	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
IHEPNEOK_00431	4.16e-31	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IHEPNEOK_00432	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
IHEPNEOK_00433	5.18e-134	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
IHEPNEOK_00434	4.62e-292	-	-	-	E	ko:K03294	-	ko00000	amino acid
IHEPNEOK_00435	1.05e-157	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IHEPNEOK_00436	2.16e-282	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
IHEPNEOK_00437	2.05e-311	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHEPNEOK_00439	2.89e-233	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
IHEPNEOK_00440	5.67e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
IHEPNEOK_00441	2.15e-299	ynbB	-	-	P	-	-	-	aluminum resistance
IHEPNEOK_00442	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IHEPNEOK_00444	0.0	-	-	-	E	-	-	-	Amino acid permease
IHEPNEOK_00445	7.82e-34	-	-	-	-	-	-	-	-
IHEPNEOK_00446	1.37e-270	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHEPNEOK_00447	1.74e-106	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
IHEPNEOK_00448	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IHEPNEOK_00449	3.34e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
IHEPNEOK_00450	1.21e-212	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IHEPNEOK_00451	7.92e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IHEPNEOK_00453	4.5e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
IHEPNEOK_00454	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHEPNEOK_00455	1.56e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
IHEPNEOK_00456	1.75e-110	-	-	-	-	-	-	-	-
IHEPNEOK_00457	8.66e-96	-	-	-	-	-	-	-	-
IHEPNEOK_00458	1.07e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
IHEPNEOK_00459	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IHEPNEOK_00460	1e-35	-	-	-	-	-	-	-	-
IHEPNEOK_00461	3.98e-259	sufI	-	-	Q	-	-	-	Multicopper oxidase
IHEPNEOK_00462	3.2e-31	sufI	-	-	Q	-	-	-	Multicopper oxidase
IHEPNEOK_00463	4.54e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
IHEPNEOK_00464	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IHEPNEOK_00466	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
IHEPNEOK_00467	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHEPNEOK_00468	3.22e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHEPNEOK_00469	1.5e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IHEPNEOK_00470	1.17e-210	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IHEPNEOK_00471	3.15e-145	yjbH	-	-	Q	-	-	-	Thioredoxin
IHEPNEOK_00472	4.73e-140	-	-	-	S	-	-	-	CYTH
IHEPNEOK_00473	1.34e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
IHEPNEOK_00474	3.05e-191	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHEPNEOK_00475	8.2e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IHEPNEOK_00476	7.7e-31	-	-	-	-	-	-	-	-
IHEPNEOK_00477	3.14e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHEPNEOK_00478	2.89e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
IHEPNEOK_00479	1.19e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHEPNEOK_00482	5.67e-25	-	-	-	-	-	-	-	-
IHEPNEOK_00485	2.65e-88	-	-	-	S	-	-	-	Virulence-associated protein E
IHEPNEOK_00491	7.79e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
IHEPNEOK_00492	5.85e-255	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
IHEPNEOK_00493	3.13e-133	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHEPNEOK_00494	1.81e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
IHEPNEOK_00495	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IHEPNEOK_00496	1.89e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
IHEPNEOK_00497	3.44e-301	ymfH	-	-	S	-	-	-	Peptidase M16
IHEPNEOK_00498	1.33e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
IHEPNEOK_00499	8.57e-161	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
IHEPNEOK_00500	1.87e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHEPNEOK_00501	1.13e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHEPNEOK_00502	1.65e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IHEPNEOK_00503	1.88e-273	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
IHEPNEOK_00504	2.7e-153	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
IHEPNEOK_00505	9.23e-67	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IHEPNEOK_00506	2.6e-232	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
IHEPNEOK_00507	1.9e-156	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
IHEPNEOK_00508	2.28e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHEPNEOK_00509	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHEPNEOK_00510	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHEPNEOK_00511	2.72e-57	-	-	-	-	-	-	-	-
IHEPNEOK_00512	2.28e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHEPNEOK_00513	9.5e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHEPNEOK_00514	3.89e-242	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IHEPNEOK_00515	1.74e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHEPNEOK_00516	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHEPNEOK_00517	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IHEPNEOK_00518	9.33e-119	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
IHEPNEOK_00519	2.61e-188	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IHEPNEOK_00520	3.52e-106	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
IHEPNEOK_00521	1.16e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IHEPNEOK_00522	2.75e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IHEPNEOK_00523	1.26e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IHEPNEOK_00524	1.21e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHEPNEOK_00525	7.36e-46	-	-	-	-	-	-	-	-
IHEPNEOK_00526	3.33e-270	-	-	-	-	-	-	-	-
IHEPNEOK_00527	6.52e-11	ABC-SBP	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
IHEPNEOK_00528	5.1e-70	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_00529	1.89e-13	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_00530	4.16e-183	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHEPNEOK_00531	1.09e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00533	4.59e-270	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
IHEPNEOK_00534	4.06e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHEPNEOK_00535	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IHEPNEOK_00536	3.16e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHEPNEOK_00537	6.54e-33	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IHEPNEOK_00538	5.95e-65	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IHEPNEOK_00539	3.12e-135	-	-	-	-	-	-	-	-
IHEPNEOK_00540	3.86e-204	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_00541	1.03e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHEPNEOK_00542	3.29e-234	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
IHEPNEOK_00543	2.29e-112	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
IHEPNEOK_00544	9.43e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IHEPNEOK_00545	1.25e-206	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
IHEPNEOK_00546	6.4e-260	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHEPNEOK_00547	6.56e-184	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00548	9.9e-173	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00549	4.19e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00550	1.1e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHEPNEOK_00551	3.57e-211	ybbR	-	-	S	-	-	-	YbbR-like protein
IHEPNEOK_00552	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHEPNEOK_00553	1.1e-191	-	-	-	S	-	-	-	hydrolase
IHEPNEOK_00554	1.54e-73	-	-	-	V	-	-	-	peptidase activity
IHEPNEOK_00555	3.22e-103	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
IHEPNEOK_00556	6e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
IHEPNEOK_00557	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IHEPNEOK_00558	5.45e-86	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHEPNEOK_00559	2.04e-79	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHEPNEOK_00560	1.54e-43	-	-	-	-	-	-	-	-
IHEPNEOK_00561	1.08e-63	-	-	-	-	-	-	-	-
IHEPNEOK_00562	3.01e-235	yliE	-	-	T	-	-	-	cyclic-guanylate-specific phosphodiesterase activity
IHEPNEOK_00563	0.0	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHEPNEOK_00565	2e-85	-	-	-	-	-	-	-	-
IHEPNEOK_00566	6.43e-110	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHEPNEOK_00567	1.87e-88	-	-	-	GM	-	-	-	epimerase
IHEPNEOK_00568	0.0	-	-	-	E	-	-	-	Amino acid permease
IHEPNEOK_00569	4.18e-133	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHEPNEOK_00570	9.34e-203	-	-	-	S	-	-	-	Phospholipase, patatin family
IHEPNEOK_00571	2.34e-209	psaA	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IHEPNEOK_00572	4.01e-122	-	-	-	S	-	-	-	VanZ like family
IHEPNEOK_00573	1.01e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
IHEPNEOK_00574	2.81e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
IHEPNEOK_00575	8.25e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
IHEPNEOK_00576	2.72e-67	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
IHEPNEOK_00577	2.11e-98	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
IHEPNEOK_00580	2.51e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
IHEPNEOK_00581	4.9e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHEPNEOK_00583	1.98e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF3644)
IHEPNEOK_00584	2.06e-241	-	-	-	S	-	-	-	Phage integrase family
IHEPNEOK_00585	6.21e-30	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IHEPNEOK_00586	2.87e-14	-	-	-	E	-	-	-	Zn peptidase
IHEPNEOK_00587	3.71e-49	ansR	3.4.21.88	-	K	ko:K01356,ko:K22299	-	ko00000,ko00002,ko01000,ko01002,ko03000,ko03400	sequence-specific DNA binding
IHEPNEOK_00592	2.04e-167	-	-	-	S	-	-	-	AAA domain
IHEPNEOK_00593	7.19e-146	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IHEPNEOK_00594	4.67e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
IHEPNEOK_00595	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
IHEPNEOK_00596	7.98e-72	-	-	-	S	-	-	-	VRR-NUC domain
IHEPNEOK_00602	1.04e-105	-	-	-	-	-	-	-	-
IHEPNEOK_00603	3.68e-60	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
IHEPNEOK_00604	1.46e-193	-	-	-	S	-	-	-	Terminase-like family
IHEPNEOK_00605	1.94e-221	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IHEPNEOK_00606	4.85e-110	-	-	-	S	-	-	-	Phage Mu protein F like protein
IHEPNEOK_00607	7.01e-52	-	-	-	S	-	-	-	Phage minor structural protein GP20
IHEPNEOK_00608	8.82e-129	-	-	-	-	-	-	-	-
IHEPNEOK_00609	6.08e-25	-	-	-	-	-	-	-	-
IHEPNEOK_00610	1.18e-42	-	-	-	-	-	-	-	-
IHEPNEOK_00611	3.24e-29	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IHEPNEOK_00614	6.37e-138	-	-	-	S	-	-	-	Phage tail sheath protein
IHEPNEOK_00615	4.07e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF2001)
IHEPNEOK_00616	3.87e-40	xkdN	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IHEPNEOK_00617	3.39e-109	-	-	-	S	-	-	-	phage tail tape measure protein
IHEPNEOK_00618	3.21e-38	-	-	-	S	-	-	-	lytic transglycosylase activity
IHEPNEOK_00619	5.56e-66	-	-	-	G	-	-	-	PFAM Phage late control gene D protein (GPD)
IHEPNEOK_00620	5.16e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IHEPNEOK_00621	1.06e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IHEPNEOK_00622	3.33e-132	-	-	-	S	-	-	-	Baseplate J-like protein
IHEPNEOK_00623	6.94e-32	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IHEPNEOK_00624	9.59e-38	-	-	-	S	-	-	-	peptidoglycan catabolic process
IHEPNEOK_00627	2.29e-40	-	-	-	-	-	-	-	-
IHEPNEOK_00630	3.7e-112	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IHEPNEOK_00631	3.55e-64	-	-	-	-	-	-	-	-
IHEPNEOK_00633	7.74e-173	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
IHEPNEOK_00634	0.0	yclK	-	-	T	-	-	-	Histidine kinase
IHEPNEOK_00635	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHEPNEOK_00636	1.27e-137	vanZ	-	-	V	-	-	-	VanZ like family
IHEPNEOK_00637	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IHEPNEOK_00638	1.02e-32	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00639	2.23e-227	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00642	2.97e-244	ampC	-	-	V	-	-	-	Beta-lactamase
IHEPNEOK_00643	3.69e-45	-	-	-	-	-	-	-	-
IHEPNEOK_00644	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
IHEPNEOK_00645	1.08e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IHEPNEOK_00646	2.77e-249	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHEPNEOK_00647	3.44e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHEPNEOK_00648	9.18e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHEPNEOK_00649	3.18e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHEPNEOK_00650	9.32e-164	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IHEPNEOK_00651	7.13e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHEPNEOK_00652	6.38e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHEPNEOK_00653	5.86e-122	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHEPNEOK_00654	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHEPNEOK_00655	1.66e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHEPNEOK_00656	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHEPNEOK_00657	3.63e-95	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IHEPNEOK_00658	7.57e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
IHEPNEOK_00659	5.61e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
IHEPNEOK_00660	4.4e-64	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
IHEPNEOK_00661	6.23e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
IHEPNEOK_00662	1.19e-279	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IHEPNEOK_00663	2.07e-102	uspA	-	-	T	-	-	-	universal stress protein
IHEPNEOK_00664	5.05e-57	-	-	-	-	-	-	-	-
IHEPNEOK_00665	1.55e-308	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
IHEPNEOK_00666	8.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IHEPNEOK_00667	3.59e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHEPNEOK_00668	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHEPNEOK_00669	1.14e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IHEPNEOK_00670	9.32e-293	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHEPNEOK_00671	2.38e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IHEPNEOK_00672	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHEPNEOK_00673	8.72e-297	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IHEPNEOK_00674	1.15e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
IHEPNEOK_00675	6.47e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
IHEPNEOK_00676	9.63e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
IHEPNEOK_00677	2.17e-175	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IHEPNEOK_00678	1.97e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
IHEPNEOK_00680	2.49e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
IHEPNEOK_00681	4.45e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IHEPNEOK_00682	2.66e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHEPNEOK_00683	1.14e-71	ftsL	-	-	D	-	-	-	Cell division protein FtsL
IHEPNEOK_00684	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IHEPNEOK_00685	1.09e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHEPNEOK_00686	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHEPNEOK_00687	2.35e-266	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHEPNEOK_00688	1.01e-188	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHEPNEOK_00689	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHEPNEOK_00690	3.72e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHEPNEOK_00691	3.21e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IHEPNEOK_00692	7.21e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
IHEPNEOK_00693	3.82e-185	ylmH	-	-	S	-	-	-	S4 domain protein
IHEPNEOK_00694	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHEPNEOK_00695	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
IHEPNEOK_00696	1.49e-131	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IHEPNEOK_00697	3.72e-36	-	-	-	-	-	-	-	-
IHEPNEOK_00698	1.56e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHEPNEOK_00699	3.66e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
IHEPNEOK_00700	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
IHEPNEOK_00701	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHEPNEOK_00702	7.5e-160	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
IHEPNEOK_00703	8.69e-149	-	-	-	S	-	-	-	repeat protein
IHEPNEOK_00704	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHEPNEOK_00705	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
IHEPNEOK_00706	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHEPNEOK_00707	3.04e-48	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IHEPNEOK_00708	8.33e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHEPNEOK_00709	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IHEPNEOK_00710	6.51e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IHEPNEOK_00711	1.31e-70	ylbG	-	-	S	-	-	-	UPF0298 protein
IHEPNEOK_00712	5.62e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
IHEPNEOK_00713	1.53e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHEPNEOK_00714	6.22e-243	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IHEPNEOK_00715	7.89e-119	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
IHEPNEOK_00716	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IHEPNEOK_00717	3.16e-232	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IHEPNEOK_00718	7.29e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IHEPNEOK_00719	1.01e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHEPNEOK_00720	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHEPNEOK_00721	2.69e-190	-	-	-	-	-	-	-	-
IHEPNEOK_00722	7.85e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHEPNEOK_00723	1.6e-276	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHEPNEOK_00724	9.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHEPNEOK_00725	1.36e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IHEPNEOK_00726	2.37e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IHEPNEOK_00727	6.83e-239	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
IHEPNEOK_00728	2.77e-08	-	-	-	-	-	-	-	-
IHEPNEOK_00729	1.46e-162	pnb	-	-	C	-	-	-	nitroreductase
IHEPNEOK_00731	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_00732	3.58e-85	-	-	-	-	-	-	-	-
IHEPNEOK_00733	2.93e-158	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IHEPNEOK_00734	2.34e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHEPNEOK_00735	2.2e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHEPNEOK_00736	9.2e-46	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IHEPNEOK_00737	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
IHEPNEOK_00738	4.71e-169	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IHEPNEOK_00739	1.98e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHEPNEOK_00740	1.03e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00741	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00742	4.53e-62	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IHEPNEOK_00743	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
IHEPNEOK_00744	8.33e-138	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHEPNEOK_00748	9.69e-59	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
IHEPNEOK_00749	2.32e-244	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00750	5.18e-109	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00751	2.71e-35	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
IHEPNEOK_00752	5.11e-18	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
IHEPNEOK_00753	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
IHEPNEOK_00754	2.02e-168	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00755	4.97e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
IHEPNEOK_00756	9.53e-99	-	-	-	-	-	-	-	-
IHEPNEOK_00757	5.24e-103	cylB	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
IHEPNEOK_00758	2.57e-138	-	-	-	L	-	-	-	Integrase
IHEPNEOK_00759	1.4e-96	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
IHEPNEOK_00761	1.01e-95	-	-	-	K	-	-	-	3.5.2 Transcription regulation
IHEPNEOK_00762	3.23e-91	-	-	-	V	-	-	-	MATE efflux family protein
IHEPNEOK_00763	1.39e-148	-	-	-	V	-	-	-	MATE efflux family protein
IHEPNEOK_00765	1.38e-49	-	-	-	T	-	-	-	diguanylate cyclase activity
IHEPNEOK_00766	2.01e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHEPNEOK_00767	2.61e-104	carB	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
IHEPNEOK_00768	0.0	carB	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.87
IHEPNEOK_00769	1.04e-48	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
IHEPNEOK_00770	1.48e-129	-	-	-	Q	-	-	-	Methyltransferase domain
IHEPNEOK_00771	1.33e-101	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHEPNEOK_00772	5.43e-87	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHEPNEOK_00773	3.01e-100	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHEPNEOK_00774	2.93e-152	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
IHEPNEOK_00775	4.36e-93	-	-	-	K	-	-	-	Transcriptional regulator
IHEPNEOK_00776	6.64e-61	-	-	-	GM	-	-	-	epimerase
IHEPNEOK_00780	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
IHEPNEOK_00781	8.85e-76	-	-	-	-	-	-	-	-
IHEPNEOK_00782	2.4e-110	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
IHEPNEOK_00783	1.63e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
IHEPNEOK_00784	6.38e-61	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
IHEPNEOK_00785	1.07e-213	-	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
IHEPNEOK_00786	1.61e-102	-	-	-	V	ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
IHEPNEOK_00787	1.91e-207	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_00788	1.4e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
IHEPNEOK_00789	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00790	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
IHEPNEOK_00791	2.14e-25	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
IHEPNEOK_00792	6.25e-206	-	-	-	L	-	-	-	Resolvase, N-terminal
IHEPNEOK_00793	2.68e-83	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHEPNEOK_00795	2.95e-56	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
IHEPNEOK_00796	7.43e-170	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
IHEPNEOK_00798	8.97e-170	-	-	-	C	-	-	-	FAD binding domain
IHEPNEOK_00799	2.1e-186	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
IHEPNEOK_00800	1.58e-128	-	-	-	S	-	-	-	YjbR
IHEPNEOK_00801	2.58e-168	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
IHEPNEOK_00802	6.3e-140	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
IHEPNEOK_00803	3.12e-96	-	-	-	C	-	-	-	FMN_bind
IHEPNEOK_00804	6.95e-12	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
IHEPNEOK_00807	2.24e-201	-	-	-	V	-	-	-	LD-carboxypeptidase
IHEPNEOK_00808	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
IHEPNEOK_00809	1.48e-223	-	-	-	-	-	-	-	-
IHEPNEOK_00810	7.45e-178	-	-	-	-	-	-	-	-
IHEPNEOK_00811	4.3e-36	-	-	-	-	-	-	-	-
IHEPNEOK_00812	3.33e-146	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHEPNEOK_00813	2.05e-177	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IHEPNEOK_00814	1.36e-146	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHEPNEOK_00815	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IHEPNEOK_00816	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IHEPNEOK_00817	1.42e-217	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00818	4.87e-101	ywnA	-	-	K	-	-	-	Transcriptional regulator
IHEPNEOK_00819	1.62e-06	-	-	-	GM	-	-	-	NmrA-like family
IHEPNEOK_00820	4.02e-100	-	-	-	GM	-	-	-	NmrA-like family
IHEPNEOK_00821	8.8e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
IHEPNEOK_00822	1.86e-289	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
IHEPNEOK_00823	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IHEPNEOK_00824	5.71e-90	-	-	-	K	-	-	-	GNAT family
IHEPNEOK_00825	2.99e-30	-	-	-	-	-	-	-	-
IHEPNEOK_00826	2.08e-41	-	-	-	-	-	-	-	-
IHEPNEOK_00827	3.77e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
IHEPNEOK_00828	5.84e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
IHEPNEOK_00829	3.14e-297	-	-	-	L	-	-	-	Transposase
IHEPNEOK_00830	1.16e-138	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IHEPNEOK_00831	4.25e-36	-	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
IHEPNEOK_00832	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
IHEPNEOK_00833	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
IHEPNEOK_00834	3.58e-34	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_00835	2.47e-58	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
IHEPNEOK_00837	6.29e-71	-	-	-	S	-	-	-	Alpha beta hydrolase
IHEPNEOK_00838	2.74e-205	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IHEPNEOK_00839	1.37e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IHEPNEOK_00840	3.04e-32	-	-	-	-	-	-	-	-
IHEPNEOK_00841	3.01e-110	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IHEPNEOK_00842	1.05e-173	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IHEPNEOK_00843	5.27e-192	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHEPNEOK_00844	1.38e-156	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IHEPNEOK_00845	7.34e-104	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
IHEPNEOK_00846	1.23e-186	-	-	-	S	-	-	-	Peptidase family M23
IHEPNEOK_00847	4.59e-34	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHEPNEOK_00848	1.28e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHEPNEOK_00849	7.82e-129	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00850	3.66e-97	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
IHEPNEOK_00851	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
IHEPNEOK_00852	6.27e-246	-	-	-	S	-	-	-	Protein of unknown function DUF262
IHEPNEOK_00853	1.98e-33	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_00854	5.4e-130	repA	-	-	S	-	-	-	Replication initiator protein A
IHEPNEOK_00856	2.95e-119	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
IHEPNEOK_00857	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IHEPNEOK_00858	2.64e-50	celA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
IHEPNEOK_00859	5.59e-41	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IHEPNEOK_00860	1.83e-258	-	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHEPNEOK_00861	2.79e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHEPNEOK_00862	1.49e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHEPNEOK_00863	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHEPNEOK_00864	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IHEPNEOK_00865	1.82e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IHEPNEOK_00866	1.05e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IHEPNEOK_00867	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHEPNEOK_00868	4.68e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IHEPNEOK_00869	1.7e-127	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHEPNEOK_00870	1.32e-248	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
IHEPNEOK_00871	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IHEPNEOK_00872	5.91e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IHEPNEOK_00874	2.08e-208	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHEPNEOK_00876	2.34e-08	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
IHEPNEOK_00877	1.04e-288	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHEPNEOK_00878	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHEPNEOK_00881	4.62e-223	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IHEPNEOK_00882	1.58e-314	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IHEPNEOK_00883	7.14e-117	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IHEPNEOK_00884	2.35e-210	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
IHEPNEOK_00885	2.27e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHEPNEOK_00886	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHEPNEOK_00887	1.02e-196	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
IHEPNEOK_00888	6.57e-177	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHEPNEOK_00889	4.39e-210	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHEPNEOK_00890	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IHEPNEOK_00891	3.72e-200	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IHEPNEOK_00892	4.64e-150	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
IHEPNEOK_00893	1.02e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHEPNEOK_00894	5.15e-216	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHEPNEOK_00899	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHEPNEOK_00900	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00901	4.21e-211	-	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_00902	6.72e-204	-	-	-	-	-	-	-	-
IHEPNEOK_00903	1.25e-128	-	-	-	I	-	-	-	PAP2 superfamily
IHEPNEOK_00904	1.06e-193	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
IHEPNEOK_00905	9.3e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHEPNEOK_00906	9.09e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2752)
IHEPNEOK_00907	1.32e-261	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
IHEPNEOK_00908	5.93e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
IHEPNEOK_00909	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_00910	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00911	6.2e-205	lysR5	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_00912	2.63e-302	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IHEPNEOK_00913	2.68e-194	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
IHEPNEOK_00914	2.08e-133	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_00915	8.63e-19	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_00916	3.57e-244	-	-	-	S	-	-	-	AI-2E family transporter
IHEPNEOK_00917	1.39e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IHEPNEOK_00918	4.47e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
IHEPNEOK_00919	5.47e-66	-	-	-	K	-	-	-	DNA-binding transcription factor activity
IHEPNEOK_00920	2.82e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHEPNEOK_00921	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IHEPNEOK_00922	7.37e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
IHEPNEOK_00923	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHEPNEOK_00924	3.9e-235	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHEPNEOK_00925	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IHEPNEOK_00926	1.04e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHEPNEOK_00927	6.5e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHEPNEOK_00928	6.35e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IHEPNEOK_00929	1.18e-128	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IHEPNEOK_00930	2.5e-51	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_00931	5.42e-32	-	-	-	L	-	-	-	Transposase
IHEPNEOK_00932	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHEPNEOK_00933	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHEPNEOK_00934	9.31e-44	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
IHEPNEOK_00935	1.34e-31	-	-	-	-	-	-	-	-
IHEPNEOK_00936	5.16e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IHEPNEOK_00937	2.93e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IHEPNEOK_00938	2.12e-70	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
IHEPNEOK_00939	1.6e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHEPNEOK_00940	2.57e-78	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHEPNEOK_00941	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHEPNEOK_00942	2.5e-57	ylxQ	-	-	J	-	-	-	ribosomal protein
IHEPNEOK_00943	1.03e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
IHEPNEOK_00944	5.54e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IHEPNEOK_00945	1.01e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IHEPNEOK_00946	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHEPNEOK_00947	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHEPNEOK_00948	1.6e-289	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IHEPNEOK_00949	1.97e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IHEPNEOK_00950	3.99e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHEPNEOK_00951	2.75e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHEPNEOK_00952	5.02e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IHEPNEOK_00953	8.09e-237	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHEPNEOK_00954	1.49e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IHEPNEOK_00955	4.73e-242	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IHEPNEOK_00956	2.26e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
IHEPNEOK_00957	5.05e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHEPNEOK_00958	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IHEPNEOK_00959	2.77e-271	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IHEPNEOK_00960	1.05e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IHEPNEOK_00961	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00962	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_00963	1.55e-42	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
IHEPNEOK_00964	1.5e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
IHEPNEOK_00965	2.53e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHEPNEOK_00966	4.13e-193	-	-	-	U	ko:K05340	-	ko00000,ko02000	ribose uptake protein RbsU
IHEPNEOK_00967	2.59e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_00968	5.91e-125	-	-	-	-	-	-	-	-
IHEPNEOK_00969	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
IHEPNEOK_00970	2.46e-315	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
IHEPNEOK_00971	0.0	-	-	-	S	-	-	-	TerB-C domain
IHEPNEOK_00972	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHEPNEOK_00973	4.71e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHEPNEOK_00974	0.0	snf	-	-	KL	-	-	-	domain protein
IHEPNEOK_00976	2.41e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IHEPNEOK_00977	1.66e-117	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHEPNEOK_00978	3.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IHEPNEOK_00979	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHEPNEOK_00980	2.27e-71	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHEPNEOK_00981	1.36e-96	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_00982	3.24e-10	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_00983	2.22e-19	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_00984	4.93e-09	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_00985	2.18e-215	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHEPNEOK_00986	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IHEPNEOK_00987	2.5e-164	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHEPNEOK_00988	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_00989	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_00990	4.18e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IHEPNEOK_00991	4.46e-227	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
IHEPNEOK_00992	3.53e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHEPNEOK_00993	3.08e-241	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IHEPNEOK_00994	1.31e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHEPNEOK_00995	3.56e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHEPNEOK_00996	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHEPNEOK_00997	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
IHEPNEOK_00998	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
IHEPNEOK_00999	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IHEPNEOK_01000	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IHEPNEOK_01005	3.04e-163	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IHEPNEOK_01006	8.19e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHEPNEOK_01007	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IHEPNEOK_01008	2.69e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IHEPNEOK_01009	2.69e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHEPNEOK_01010	4.27e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHEPNEOK_01011	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHEPNEOK_01012	1.28e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IHEPNEOK_01013	2.84e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IHEPNEOK_01014	8.37e-66	-	-	-	-	-	-	-	-
IHEPNEOK_01015	6.8e-46	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHEPNEOK_01016	1.2e-17	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01017	3.4e-61	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
IHEPNEOK_01018	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IHEPNEOK_01019	1.57e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
IHEPNEOK_01020	1.16e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IHEPNEOK_01021	2.38e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHEPNEOK_01022	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHEPNEOK_01023	7.56e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHEPNEOK_01024	7.64e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHEPNEOK_01025	6.3e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
IHEPNEOK_01026	8.59e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHEPNEOK_01027	9.38e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHEPNEOK_01028	2.67e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IHEPNEOK_01029	5.61e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IHEPNEOK_01030	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IHEPNEOK_01031	3.7e-118	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
IHEPNEOK_01032	3.77e-76	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_01033	1.13e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IHEPNEOK_01034	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IHEPNEOK_01035	2.37e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHEPNEOK_01036	2.39e-253	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IHEPNEOK_01037	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHEPNEOK_01038	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHEPNEOK_01039	1.98e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHEPNEOK_01040	8.7e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHEPNEOK_01041	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IHEPNEOK_01042	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHEPNEOK_01043	1.59e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHEPNEOK_01044	6.03e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHEPNEOK_01045	1.66e-55	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
IHEPNEOK_01046	7.89e-150	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHEPNEOK_01047	1.95e-127	-	-	-	P	-	-	-	nitrite transmembrane transporter activity
IHEPNEOK_01048	1.29e-299	-	-	-	-	-	-	-	-
IHEPNEOK_01049	0.0	-	-	-	S	-	-	-	SH3-like domain
IHEPNEOK_01050	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IHEPNEOK_01052	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IHEPNEOK_01053	3.42e-276	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_01055	1.84e-194	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
IHEPNEOK_01056	9.35e-209	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IHEPNEOK_01057	2.03e-44	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01058	5.42e-32	-	-	-	L	-	-	-	Transposase
IHEPNEOK_01059	1.32e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
IHEPNEOK_01060	3.13e-260	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
IHEPNEOK_01061	4.71e-239	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHEPNEOK_01062	1.37e-75	-	-	-	-	-	-	-	-
IHEPNEOK_01063	6.84e-105	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01064	3.25e-35	-	-	-	L	-	-	-	Transposase
IHEPNEOK_01065	1.47e-83	-	-	-	S	-	-	-	Domain of unknown function DUF1828
IHEPNEOK_01066	6.13e-278	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IHEPNEOK_01067	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IHEPNEOK_01068	5.59e-174	ynbB	-	-	P	-	-	-	aluminum resistance
IHEPNEOK_01069	2.41e-187	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHEPNEOK_01070	8.9e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
IHEPNEOK_01071	2.45e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
IHEPNEOK_01072	2.78e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
IHEPNEOK_01073	1.95e-134	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHEPNEOK_01074	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IHEPNEOK_01075	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IHEPNEOK_01076	0.0	-	-	-	S	-	-	-	membrane
IHEPNEOK_01077	5.38e-75	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHEPNEOK_01078	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHEPNEOK_01079	4.12e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHEPNEOK_01080	9.83e-81	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
IHEPNEOK_01081	3.8e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHEPNEOK_01082	5.39e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IHEPNEOK_01083	1.11e-189	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHEPNEOK_01084	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHEPNEOK_01085	1.96e-164	csrR	-	-	K	-	-	-	response regulator
IHEPNEOK_01086	2.09e-130	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
IHEPNEOK_01087	5.85e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IHEPNEOK_01088	1.46e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHEPNEOK_01089	6.76e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
IHEPNEOK_01090	6.43e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHEPNEOK_01091	4.71e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
IHEPNEOK_01092	2.91e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHEPNEOK_01093	1.37e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IHEPNEOK_01094	3.99e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHEPNEOK_01095	9.08e-300	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
IHEPNEOK_01096	2.29e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
IHEPNEOK_01097	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
IHEPNEOK_01098	1.51e-44	-	-	-	-	-	-	-	-
IHEPNEOK_01099	4.25e-57	-	-	-	-	-	-	-	-
IHEPNEOK_01100	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHEPNEOK_01101	2.36e-216	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IHEPNEOK_01102	3.85e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
IHEPNEOK_01103	1.57e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHEPNEOK_01104	1.03e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHEPNEOK_01105	3.45e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHEPNEOK_01106	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHEPNEOK_01107	1.31e-49	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_01108	1.49e-144	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_01109	1.8e-57	-	-	-	EGP	-	-	-	Major facilitator Superfamily
IHEPNEOK_01110	5.04e-143	-	-	-	K	-	-	-	Helix-turn-helix domain
IHEPNEOK_01111	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IHEPNEOK_01112	1.2e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHEPNEOK_01113	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
IHEPNEOK_01114	1.64e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHEPNEOK_01115	1.89e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_01116	8.64e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01117	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
IHEPNEOK_01118	4.02e-71	-	-	-	-	-	-	-	-
IHEPNEOK_01119	5.79e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHEPNEOK_01120	2.5e-173	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHEPNEOK_01121	9.14e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHEPNEOK_01122	8.28e-199	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IHEPNEOK_01123	5.07e-64	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHEPNEOK_01124	1.81e-86	aroK	1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4	-	F	ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03000	shikimate kinase activity
IHEPNEOK_01125	1.28e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
IHEPNEOK_01126	0.0	yhaN	-	-	L	-	-	-	AAA domain
IHEPNEOK_01127	1.54e-289	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
IHEPNEOK_01128	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IHEPNEOK_01129	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IHEPNEOK_01130	7.86e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IHEPNEOK_01131	9.99e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
IHEPNEOK_01132	9.16e-124	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IHEPNEOK_01133	6.37e-76	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IHEPNEOK_01134	1.81e-76	-	-	-	-	-	-	-	-
IHEPNEOK_01135	1.06e-71	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_01136	5.11e-47	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_01138	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IHEPNEOK_01139	1.91e-201	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHEPNEOK_01140	2.91e-294	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IHEPNEOK_01142	1.57e-90	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IHEPNEOK_01143	2.9e-311	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IHEPNEOK_01144	2.65e-228	-	-	-	-	-	-	-	-
IHEPNEOK_01145	1.99e-87	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHEPNEOK_01146	9.16e-69	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHEPNEOK_01147	1.71e-205	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHEPNEOK_01148	1.02e-102	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHEPNEOK_01149	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
IHEPNEOK_01150	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IHEPNEOK_01151	3.52e-91	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01152	2.31e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IHEPNEOK_01153	0.0	bmr3_1	-	-	EGP	ko:K18935	-	ko00000,ko02000	Sugar (and other) transporter
IHEPNEOK_01154	2.82e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHEPNEOK_01159	3.5e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHEPNEOK_01160	9.6e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
IHEPNEOK_01161	1.1e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_01162	6.4e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
IHEPNEOK_01163	1.56e-203	yicL	-	-	EG	-	-	-	EamA-like transporter family
IHEPNEOK_01164	4.51e-65	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IHEPNEOK_01165	1.06e-37	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
IHEPNEOK_01166	8.45e-170	-	-	-	L	-	-	-	Transposase
IHEPNEOK_01167	5.32e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHEPNEOK_01168	2.49e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHEPNEOK_01169	1.98e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IHEPNEOK_01170	4.3e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHEPNEOK_01171	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHEPNEOK_01172	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHEPNEOK_01173	8.49e-83	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IHEPNEOK_01174	8.33e-33	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01175	7.05e-94	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01177	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
IHEPNEOK_01178	7.46e-50	-	-	-	-	-	-	-	-
IHEPNEOK_01179	3.87e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
IHEPNEOK_01180	1.87e-33	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHEPNEOK_01181	2.8e-185	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHEPNEOK_01182	2.82e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHEPNEOK_01183	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
IHEPNEOK_01184	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_01185	1.36e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHEPNEOK_01186	7.6e-118	ymdB	-	-	S	-	-	-	Macro domain protein
IHEPNEOK_01187	1.67e-46	-	-	-	-	-	-	-	-
IHEPNEOK_01188	6.03e-197	-	-	-	-	-	-	-	-
IHEPNEOK_01191	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IHEPNEOK_01192	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IHEPNEOK_01194	0.0	-	-	-	M	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
IHEPNEOK_01195	7.07e-222	citI	-	-	K	-	-	-	Putative sugar-binding domain
IHEPNEOK_01196	3.17e-56	lysM	-	-	M	-	-	-	LysM domain
IHEPNEOK_01197	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
IHEPNEOK_01198	5.7e-46	ydgI	-	-	C	-	-	-	Nitroreductase family
IHEPNEOK_01199	2.55e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
IHEPNEOK_01200	4.89e-152	-	-	-	-	-	-	-	-
IHEPNEOK_01201	1.69e-178	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
IHEPNEOK_01202	3.14e-81	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHEPNEOK_01203	4.36e-156	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
IHEPNEOK_01204	9.21e-115	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
IHEPNEOK_01205	1.76e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IHEPNEOK_01206	1.68e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01207	2.66e-218	-	-	-	K	-	-	-	WYL domain
IHEPNEOK_01208	1.33e-87	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
IHEPNEOK_01209	2.06e-14	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IHEPNEOK_01210	9.24e-114	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHEPNEOK_01211	1.79e-178	-	-	-	-	-	-	-	-
IHEPNEOK_01213	1.32e-137	-	-	-	-	-	-	-	-
IHEPNEOK_01214	6.6e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IHEPNEOK_01216	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
IHEPNEOK_01217	4.76e-127	-	-	-	K	-	-	-	WHG domain
IHEPNEOK_01218	7.16e-127	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IHEPNEOK_01219	6.08e-125	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
IHEPNEOK_01220	2.05e-182	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
IHEPNEOK_01221	1.64e-238	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHEPNEOK_01222	2.13e-112	cvpA	-	-	S	-	-	-	Colicin V production protein
IHEPNEOK_01223	3.68e-170	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
IHEPNEOK_01224	1.09e-184	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IHEPNEOK_01225	2.37e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
IHEPNEOK_01226	2.91e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IHEPNEOK_01227	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
IHEPNEOK_01228	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHEPNEOK_01229	4.63e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
IHEPNEOK_01230	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01231	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHEPNEOK_01232	3.03e-159	vanR	-	-	K	-	-	-	response regulator
IHEPNEOK_01233	5.71e-281	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IHEPNEOK_01234	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHEPNEOK_01235	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IHEPNEOK_01236	7.41e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
IHEPNEOK_01237	1.41e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IHEPNEOK_01238	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
IHEPNEOK_01239	6.84e-184	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_01240	6.92e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHEPNEOK_01241	2.09e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
IHEPNEOK_01242	5.07e-74	-	-	-	KT	-	-	-	response to antibiotic
IHEPNEOK_01243	2.3e-130	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IHEPNEOK_01244	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IHEPNEOK_01245	0.0	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_01246	1.12e-264	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_01248	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
IHEPNEOK_01249	1.67e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
IHEPNEOK_01250	1.04e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
IHEPNEOK_01251	6.85e-103	-	-	-	-	-	-	-	-
IHEPNEOK_01252	4.02e-145	-	-	-	-	-	-	-	-
IHEPNEOK_01253	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
IHEPNEOK_01254	2.89e-64	-	-	-	-	-	-	-	-
IHEPNEOK_01255	1.5e-124	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
IHEPNEOK_01256	5.18e-109	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
IHEPNEOK_01257	1.62e-255	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_01258	1.01e-104	lytE	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
IHEPNEOK_01259	2.88e-157	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHEPNEOK_01260	1.27e-159	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHEPNEOK_01261	1.17e-156	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
IHEPNEOK_01262	1.75e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHEPNEOK_01263	7.97e-229	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_01264	1.33e-157	epsB	-	-	M	-	-	-	biosynthesis protein
IHEPNEOK_01265	7.58e-151	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
IHEPNEOK_01266	3.29e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
IHEPNEOK_01267	4.26e-50	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IHEPNEOK_01268	1.75e-93	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
IHEPNEOK_01269	4.69e-113	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
IHEPNEOK_01270	2.84e-109	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
IHEPNEOK_01271	5.29e-112	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IHEPNEOK_01273	2.92e-240	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IHEPNEOK_01274	1.18e-36	-	-	-	M	-	-	-	Glycosyl transferases group 1
IHEPNEOK_01275	5.49e-53	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01276	1.02e-37	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01277	4.75e-90	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01278	6.14e-143	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IHEPNEOK_01279	1.48e-43	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
IHEPNEOK_01280	4.89e-20	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IHEPNEOK_01281	6.13e-257	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IHEPNEOK_01282	5.26e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IHEPNEOK_01283	2.01e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives
IHEPNEOK_01284	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
IHEPNEOK_01285	5.44e-149	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
IHEPNEOK_01286	1.31e-17	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHEPNEOK_01287	1.59e-144	-	-	-	L	-	-	-	nuclease
IHEPNEOK_01288	2.21e-197	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IHEPNEOK_01289	5.85e-15	-	-	-	-	-	-	-	-
IHEPNEOK_01290	3.07e-225	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IHEPNEOK_01291	3.76e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHEPNEOK_01292	1.22e-251	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHEPNEOK_01293	2.5e-09	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IHEPNEOK_01294	5.76e-52	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
IHEPNEOK_01295	1.58e-35	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IHEPNEOK_01296	4.98e-46	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IHEPNEOK_01297	6.63e-125	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01298	2.59e-199	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_01300	1.38e-37	-	-	-	-	-	-	-	-
IHEPNEOK_01301	1e-117	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01302	3.36e-72	luxA_2	-	-	C	-	-	-	Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
IHEPNEOK_01303	4.71e-53	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHEPNEOK_01304	1.76e-233	-	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Rossmann-like domain
IHEPNEOK_01305	5.63e-77	-	-	-	K	-	-	-	sequence-specific DNA binding
IHEPNEOK_01306	6.52e-126	-	-	-	-	-	-	-	-
IHEPNEOK_01307	2.55e-95	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
IHEPNEOK_01309	6.05e-252	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
IHEPNEOK_01310	4.7e-169	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
IHEPNEOK_01311	6.28e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
IHEPNEOK_01312	5.29e-193	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
IHEPNEOK_01313	1.69e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
IHEPNEOK_01314	4.61e-220	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
IHEPNEOK_01315	1.59e-233	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IHEPNEOK_01316	2.39e-253	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
IHEPNEOK_01317	0.0	epsIIL	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
IHEPNEOK_01318	9.39e-230	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
IHEPNEOK_01319	9.1e-111	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
IHEPNEOK_01320	8.48e-285	-	-	-	-	-	-	-	-
IHEPNEOK_01322	3.67e-48	-	-	-	I	-	-	-	Acyltransferase family
IHEPNEOK_01324	8.58e-09	-	-	-	M	-	-	-	Peptidase_C39 like family
IHEPNEOK_01325	1.32e-58	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
IHEPNEOK_01326	3.85e-34	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
IHEPNEOK_01327	1.1e-96	-	-	-	S	-	-	-	VanZ like family
IHEPNEOK_01328	3.27e-96	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
IHEPNEOK_01329	4.45e-127	-	-	-	S	-	-	-	VanZ like family
IHEPNEOK_01330	2.97e-71	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
IHEPNEOK_01331	3.93e-104	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
IHEPNEOK_01333	0.0	-	3.1.4.46, 3.2.1.99	GH43	N	ko:K01126,ko:K06113	ko00564,map00564	ko00000,ko00001,ko01000	domain, Protein
IHEPNEOK_01335	5.55e-54	-	-	-	-	-	-	-	-
IHEPNEOK_01336	1.35e-172	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IHEPNEOK_01337	9.13e-160	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
IHEPNEOK_01338	3.82e-149	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
IHEPNEOK_01339	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IHEPNEOK_01340	2.48e-35	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IHEPNEOK_01341	1.04e-64	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_01342	1.12e-110	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
IHEPNEOK_01344	1.17e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
IHEPNEOK_01345	4.26e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IHEPNEOK_01346	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IHEPNEOK_01347	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHEPNEOK_01348	2.31e-100	-	-	-	S	-	-	-	Helix-turn-helix domain
IHEPNEOK_01349	1.24e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IHEPNEOK_01350	3.13e-252	-	-	-	-	-	-	-	-
IHEPNEOK_01351	1.01e-19	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IHEPNEOK_01352	1.89e-138	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01353	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
IHEPNEOK_01354	3.34e-12	-	-	-	S	-	-	-	PAS domain
IHEPNEOK_01355	7.02e-55	-	-	-	GK	-	-	-	ROK family
IHEPNEOK_01358	1.52e-201	dkgB	-	-	S	-	-	-	reductase
IHEPNEOK_01359	2.59e-175	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
IHEPNEOK_01360	6.86e-56	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	dipeptidase activity
IHEPNEOK_01361	1.21e-135	-	-	-	-	-	-	-	-
IHEPNEOK_01362	3.16e-111	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
IHEPNEOK_01363	8.98e-224	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
IHEPNEOK_01364	2.82e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
IHEPNEOK_01365	1.69e-203	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
IHEPNEOK_01366	2.2e-36	-	-	-	-	-	-	-	-
IHEPNEOK_01367	9.52e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHEPNEOK_01368	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
IHEPNEOK_01369	1.84e-226	-	-	-	-	-	-	-	-
IHEPNEOK_01370	1.88e-252	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01371	9.48e-165	-	-	-	F	-	-	-	glutamine amidotransferase
IHEPNEOK_01372	1.32e-122	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
IHEPNEOK_01373	1.64e-201	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
IHEPNEOK_01374	1.4e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
IHEPNEOK_01375	5.99e-137	-	-	-	S	-	-	-	SNARE associated Golgi protein
IHEPNEOK_01376	1.95e-119	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHEPNEOK_01377	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHEPNEOK_01378	8.27e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
IHEPNEOK_01379	5.03e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IHEPNEOK_01380	3.16e-05	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IHEPNEOK_01381	4.72e-209	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IHEPNEOK_01382	2.29e-60	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
IHEPNEOK_01383	2.69e-183	-	-	-	G	-	-	-	polysaccharide deacetylase
IHEPNEOK_01384	1.98e-13	-	-	-	G	-	-	-	polysaccharide deacetylase
IHEPNEOK_01387	8.43e-66	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
IHEPNEOK_01389	8.75e-160	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHEPNEOK_01390	3.01e-162	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IHEPNEOK_01391	7.4e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
IHEPNEOK_01392	8.81e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHEPNEOK_01393	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
IHEPNEOK_01394	6.26e-101	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHEPNEOK_01395	3.61e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHEPNEOK_01396	1.87e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHEPNEOK_01397	1.53e-158	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IHEPNEOK_01398	5.44e-230	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
IHEPNEOK_01399	1.31e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHEPNEOK_01400	4.78e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHEPNEOK_01401	3.02e-235	ydbI	-	-	K	-	-	-	AI-2E family transporter
IHEPNEOK_01402	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
IHEPNEOK_01403	1.38e-284	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01404	1.22e-193	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IHEPNEOK_01405	1.31e-61	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
IHEPNEOK_01406	1.3e-31	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01407	1.34e-36	-	-	-	-	-	-	-	-
IHEPNEOK_01408	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IHEPNEOK_01409	8.64e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IHEPNEOK_01410	2.42e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHEPNEOK_01411	1.26e-73	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHEPNEOK_01412	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHEPNEOK_01413	2.28e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
IHEPNEOK_01414	1.16e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHEPNEOK_01415	3.13e-308	-	-	-	S	-	-	-	Putative threonine/serine exporter
IHEPNEOK_01416	6.16e-282	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
IHEPNEOK_01417	1.15e-275	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
IHEPNEOK_01418	4.08e-249	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IHEPNEOK_01419	8.71e-207	sptS	-	-	T	-	-	-	Histidine kinase
IHEPNEOK_01420	4.75e-61	sptS	-	-	T	-	-	-	Histidine kinase
IHEPNEOK_01421	3.26e-151	dltr	-	-	K	-	-	-	response regulator
IHEPNEOK_01422	8.14e-143	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
IHEPNEOK_01423	1.15e-203	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
IHEPNEOK_01424	2.28e-223	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHEPNEOK_01425	1.47e-151	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
IHEPNEOK_01426	3.84e-169	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
IHEPNEOK_01427	1.62e-235	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
IHEPNEOK_01428	1.79e-139	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
IHEPNEOK_01429	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
IHEPNEOK_01430	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
IHEPNEOK_01432	8.89e-26	-	-	-	-	-	-	-	-
IHEPNEOK_01434	1.26e-255	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IHEPNEOK_01436	5.36e-93	-	-	-	-	-	-	-	-
IHEPNEOK_01437	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHEPNEOK_01439	2.61e-35	-	-	-	-	-	-	-	-
IHEPNEOK_01440	8e-145	-	-	-	K	ko:K13928	-	ko00000,ko03000	DNA-binding transcription factor activity
IHEPNEOK_01441	3.68e-158	-	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_01442	1.27e-32	-	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_01443	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IHEPNEOK_01444	1.68e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
IHEPNEOK_01445	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHEPNEOK_01446	2.29e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IHEPNEOK_01447	8.74e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IHEPNEOK_01448	3.5e-139	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IHEPNEOK_01449	5.23e-06	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IHEPNEOK_01450	1.16e-150	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHEPNEOK_01451	4.13e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IHEPNEOK_01452	5.3e-137	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHEPNEOK_01453	2.77e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHEPNEOK_01454	2.22e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHEPNEOK_01455	1.26e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
IHEPNEOK_01456	4.38e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
IHEPNEOK_01457	1.14e-120	-	-	-	I	-	-	-	Acyltransferase family
IHEPNEOK_01459	2.01e-51	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	anion transmembrane transporter activity
IHEPNEOK_01460	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IHEPNEOK_01461	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHEPNEOK_01462	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IHEPNEOK_01463	2.87e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IHEPNEOK_01464	3.38e-116	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHEPNEOK_01465	1.63e-73	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
IHEPNEOK_01466	1.01e-19	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IHEPNEOK_01467	1.37e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IHEPNEOK_01469	1.06e-82	-	-	-	-	-	-	-	-
IHEPNEOK_01470	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
IHEPNEOK_01471	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHEPNEOK_01472	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IHEPNEOK_01473	7.34e-178	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IHEPNEOK_01474	4.62e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHEPNEOK_01475	0.0	oatA	-	-	I	-	-	-	Acyltransferase
IHEPNEOK_01476	6.47e-298	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHEPNEOK_01477	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHEPNEOK_01478	6.15e-235	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
IHEPNEOK_01479	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
IHEPNEOK_01480	3.95e-224	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_01481	1.24e-239	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
IHEPNEOK_01482	2.34e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHEPNEOK_01483	6.58e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IHEPNEOK_01484	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IHEPNEOK_01485	3.61e-214	yvbU	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_01486	1.03e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
IHEPNEOK_01487	7.58e-85	-	-	-	E	-	-	-	Methionine synthase
IHEPNEOK_01488	1.46e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IHEPNEOK_01489	1.34e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
IHEPNEOK_01490	4.03e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
IHEPNEOK_01491	3.84e-185	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHEPNEOK_01492	2.89e-118	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
IHEPNEOK_01493	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IHEPNEOK_01494	2.89e-77	-	-	-	-	-	-	-	-
IHEPNEOK_01495	2.49e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IHEPNEOK_01496	6.81e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHEPNEOK_01498	5.67e-34	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHEPNEOK_01499	5.42e-56	-	-	-	-	-	-	-	-
IHEPNEOK_01500	1.1e-27	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHEPNEOK_01501	3.99e-196	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
IHEPNEOK_01502	1.78e-147	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHEPNEOK_01503	1.01e-87	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IHEPNEOK_01504	3.11e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IHEPNEOK_01505	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHEPNEOK_01506	1.92e-67	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IHEPNEOK_01507	6.34e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHEPNEOK_01508	3.09e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IHEPNEOK_01509	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHEPNEOK_01510	4.29e-295	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHEPNEOK_01511	1.89e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
IHEPNEOK_01512	2e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHEPNEOK_01513	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHEPNEOK_01514	1.21e-70	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IHEPNEOK_01515	1.02e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHEPNEOK_01516	2.85e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHEPNEOK_01517	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHEPNEOK_01518	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHEPNEOK_01519	2.72e-96	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHEPNEOK_01520	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHEPNEOK_01521	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHEPNEOK_01522	1.23e-158	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHEPNEOK_01523	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
IHEPNEOK_01524	1.43e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHEPNEOK_01525	7.47e-123	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
IHEPNEOK_01526	4.78e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
IHEPNEOK_01527	5.44e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHEPNEOK_01528	3.83e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
IHEPNEOK_01529	1.19e-180	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
IHEPNEOK_01530	9.14e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHEPNEOK_01531	2.21e-72	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IHEPNEOK_01532	9.88e-205	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IHEPNEOK_01533	6.39e-71	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
IHEPNEOK_01534	2.32e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHEPNEOK_01535	2.21e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IHEPNEOK_01536	3.6e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHEPNEOK_01537	1.9e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHEPNEOK_01538	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHEPNEOK_01539	1.93e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHEPNEOK_01540	1.79e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IHEPNEOK_01541	2.31e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHEPNEOK_01542	9.29e-200	-	-	-	-	-	-	-	-
IHEPNEOK_01543	1.92e-60	-	-	-	-	-	-	-	-
IHEPNEOK_01544	9.36e-20	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
IHEPNEOK_01545	7.54e-264	pbpX1	-	-	V	-	-	-	Beta-lactamase
IHEPNEOK_01546	5.84e-274	pbpX	-	-	V	-	-	-	Beta-lactamase
IHEPNEOK_01547	1.49e-54	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHEPNEOK_01548	1.84e-27	-	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
IHEPNEOK_01549	1.22e-15	rpiB2	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
IHEPNEOK_01551	2.57e-109	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHEPNEOK_01552	9.22e-18	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
IHEPNEOK_01553	1.83e-186	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01554	2.75e-111	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01555	1.42e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHEPNEOK_01556	1.35e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHEPNEOK_01557	2.89e-260	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_01558	5.15e-91	-	-	-	-	-	-	-	-
IHEPNEOK_01559	8.03e-295	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
IHEPNEOK_01560	1.04e-244	-	-	-	S	-	-	-	Glycosyl transferase family 2
IHEPNEOK_01561	4.45e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHEPNEOK_01562	3.27e-91	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHEPNEOK_01563	5.63e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IHEPNEOK_01564	3.07e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IHEPNEOK_01565	7.32e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IHEPNEOK_01566	1.49e-38	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHEPNEOK_01567	2.38e-51	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
IHEPNEOK_01568	3.94e-124	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHEPNEOK_01569	2.17e-115	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHEPNEOK_01570	2.02e-153	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IHEPNEOK_01571	3.19e-45	-	-	-	-	-	-	-	-
IHEPNEOK_01572	5.81e-131	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
IHEPNEOK_01573	5.44e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHEPNEOK_01574	6.26e-101	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHEPNEOK_01575	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IHEPNEOK_01576	7.09e-136	-	-	-	F	-	-	-	NUDIX domain
IHEPNEOK_01577	5.29e-205	-	-	-	K	-	-	-	LysR substrate binding domain
IHEPNEOK_01578	2.3e-231	-	-	-	S	-	-	-	Conserved hypothetical protein 698
IHEPNEOK_01579	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHEPNEOK_01581	1.88e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IHEPNEOK_01582	1.26e-79	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
IHEPNEOK_01583	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01584	3.57e-120	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IHEPNEOK_01585	5.87e-297	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHEPNEOK_01586	6.69e-228	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
IHEPNEOK_01587	1.32e-31	-	6.3.4.18, 6.3.5.5	-	F	ko:K01589,ko:K01955,ko:K16181	ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	5-(carboxyamino)imidazole ribonucleotide synthase activity
IHEPNEOK_01588	9.52e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IHEPNEOK_01589	6.14e-259	-	-	-	-	-	-	-	-
IHEPNEOK_01590	9.66e-272	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IHEPNEOK_01591	4.78e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
IHEPNEOK_01592	5.52e-92	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01593	2.95e-20	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01594	5.94e-141	-	-	-	T	-	-	-	EAL domain
IHEPNEOK_01595	7.24e-15	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01596	4.21e-111	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IHEPNEOK_01597	0.0	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
IHEPNEOK_01598	4.99e-186	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
IHEPNEOK_01599	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01600	1.32e-130	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
IHEPNEOK_01601	2.84e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
IHEPNEOK_01602	7.2e-56	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHEPNEOK_01603	5.47e-227	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHEPNEOK_01604	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
IHEPNEOK_01605	1.27e-217	potA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_01606	2.53e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
IHEPNEOK_01612	1.3e-205	-	-	-	J	-	-	-	Methyltransferase
IHEPNEOK_01613	1.39e-99	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IHEPNEOK_01614	2.11e-231	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
IHEPNEOK_01630	1.17e-119	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01631	8.15e-94	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
IHEPNEOK_01632	2.26e-49	-	-	-	-	-	-	-	-
IHEPNEOK_01633	1.15e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHEPNEOK_01636	2.91e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IHEPNEOK_01637	7.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IHEPNEOK_01638	4.17e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
IHEPNEOK_01639	9.06e-182	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHEPNEOK_01640	1.34e-145	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
IHEPNEOK_01641	2.5e-161	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
IHEPNEOK_01642	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IHEPNEOK_01643	2.71e-28	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IHEPNEOK_01644	0.000856	ccmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IHEPNEOK_01646	7.4e-84	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
IHEPNEOK_01648	3.17e-156	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
IHEPNEOK_01649	2.11e-60	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
IHEPNEOK_01650	6.12e-167	-	-	-	S	-	-	-	Glycosyl hydrolases family 18
IHEPNEOK_01651	6.6e-134	M1-740	-	-	I	-	-	-	NUDIX domain
IHEPNEOK_01652	6.09e-129	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
IHEPNEOK_01653	1.1e-179	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHEPNEOK_01654	1.06e-190	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IHEPNEOK_01655	8.58e-174	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IHEPNEOK_01656	1.43e-135	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
IHEPNEOK_01658	4.57e-87	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHEPNEOK_01659	2.84e-266	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHEPNEOK_01660	2.53e-240	-	-	-	T	-	-	-	diguanylate cyclase
IHEPNEOK_01661	2.98e-135	-	-	-	-	-	-	-	-
IHEPNEOK_01662	1.11e-194	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_01663	6.47e-12	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IHEPNEOK_01664	1.82e-65	-	-	-	V	ko:K06147	-	ko00000,ko02000	(ABC) transporter
IHEPNEOK_01665	1.63e-07	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01666	2.39e-55	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01667	1.05e-68	-	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
IHEPNEOK_01668	2.51e-235	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHEPNEOK_01669	3.97e-38	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHEPNEOK_01670	1.1e-144	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHEPNEOK_01671	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHEPNEOK_01672	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHEPNEOK_01673	2.02e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
IHEPNEOK_01674	9.25e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHEPNEOK_01675	3.3e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
IHEPNEOK_01676	1.22e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
IHEPNEOK_01677	7.03e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
IHEPNEOK_01678	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IHEPNEOK_01679	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IHEPNEOK_01680	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IHEPNEOK_01681	4.66e-93	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
IHEPNEOK_01682	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
IHEPNEOK_01683	1.24e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
IHEPNEOK_01684	4.71e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHEPNEOK_01685	4.33e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
IHEPNEOK_01686	4.46e-92	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
IHEPNEOK_01687	1.54e-71	-	-	-	I	-	-	-	acetylesterase activity
IHEPNEOK_01688	6.48e-243	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_01689	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
IHEPNEOK_01690	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
IHEPNEOK_01691	6.44e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHEPNEOK_01692	8.99e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IHEPNEOK_01693	5.35e-85	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHEPNEOK_01694	5.87e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IHEPNEOK_01695	1.65e-135	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHEPNEOK_01696	1.93e-84	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
IHEPNEOK_01697	1.28e-77	-	-	-	-	-	-	-	-
IHEPNEOK_01698	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
IHEPNEOK_01699	1.3e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHEPNEOK_01700	1.6e-217	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IHEPNEOK_01701	1.88e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IHEPNEOK_01702	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
IHEPNEOK_01703	4.02e-58	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
IHEPNEOK_01704	1.39e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
IHEPNEOK_01705	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
IHEPNEOK_01706	8.41e-203	-	-	-	S	-	-	-	EDD domain protein, DegV family
IHEPNEOK_01707	1.83e-225	-	-	-	-	-	-	-	-
IHEPNEOK_01708	2.26e-212	-	-	-	EG	-	-	-	EamA-like transporter family
IHEPNEOK_01709	5.55e-155	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_01710	3.4e-114	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHEPNEOK_01711	2.77e-105	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHEPNEOK_01712	5.88e-107	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHEPNEOK_01713	5.73e-149	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
IHEPNEOK_01714	2.84e-16	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
IHEPNEOK_01715	3.44e-117	yfhC	-	-	C	-	-	-	Nitroreductase family
IHEPNEOK_01716	6.33e-78	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IHEPNEOK_01718	2.13e-256	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
IHEPNEOK_01719	1.41e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IHEPNEOK_01720	6.23e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
IHEPNEOK_01721	1.81e-99	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
IHEPNEOK_01722	3.44e-177	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHEPNEOK_01723	4.41e-07	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
IHEPNEOK_01724	2.2e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
IHEPNEOK_01725	4.69e-98	-	-	-	GM	-	-	-	NmrA-like family
IHEPNEOK_01726	2.04e-227	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
IHEPNEOK_01727	1.42e-107	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
IHEPNEOK_01728	1.42e-179	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
IHEPNEOK_01729	7.39e-314	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
IHEPNEOK_01731	2.05e-10	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IHEPNEOK_01732	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
IHEPNEOK_01733	6.48e-87	-	-	-	S	-	-	-	ASCH domain
IHEPNEOK_01734	6.07e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHEPNEOK_01735	1.13e-91	-	-	-	-	-	-	-	-
IHEPNEOK_01736	4.18e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IHEPNEOK_01737	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01738	1.01e-86	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
IHEPNEOK_01739	5.44e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHEPNEOK_01740	1.12e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHEPNEOK_01741	1.36e-308	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
IHEPNEOK_01742	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHEPNEOK_01743	0.000111	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
IHEPNEOK_01744	3.84e-65	-	-	-	-	-	-	-	-
IHEPNEOK_01745	1.17e-289	-	-	-	S	-	-	-	Membrane
IHEPNEOK_01746	3.7e-82	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
IHEPNEOK_01747	1.04e-110	ykuL	-	-	S	-	-	-	(CBS) domain
IHEPNEOK_01748	0.0	cadA	-	-	P	-	-	-	P-type ATPase
IHEPNEOK_01749	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
IHEPNEOK_01750	3.3e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IHEPNEOK_01751	2.3e-255	-	-	-	S	-	-	-	DUF218 domain
IHEPNEOK_01752	2.36e-249	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHEPNEOK_01754	1.99e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
IHEPNEOK_01755	4.2e-241	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
IHEPNEOK_01756	4.45e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
IHEPNEOK_01757	1.6e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHEPNEOK_01758	1.82e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
IHEPNEOK_01759	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
IHEPNEOK_01760	4.35e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHEPNEOK_01761	1.48e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IHEPNEOK_01762	1.51e-26	-	-	-	EGP	-	-	-	Major Facilitator
IHEPNEOK_01763	1.78e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
IHEPNEOK_01764	2.58e-163	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHEPNEOK_01766	3.02e-19	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
IHEPNEOK_01768	6.57e-226	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
IHEPNEOK_01769	4.44e-51	-	-	-	-	-	-	-	-
IHEPNEOK_01770	6.66e-159	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IHEPNEOK_01771	4.66e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
IHEPNEOK_01772	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IHEPNEOK_01773	7.15e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01774	1.89e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IHEPNEOK_01775	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
IHEPNEOK_01776	2.56e-20	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IHEPNEOK_01777	3.05e-91	-	-	-	-	-	-	-	-
IHEPNEOK_01778	3.79e-119	-	-	-	-	-	-	-	-
IHEPNEOK_01779	1.05e-147	-	-	-	-	-	-	-	-
IHEPNEOK_01780	3.17e-134	-	-	-	-	-	-	-	-
IHEPNEOK_01781	2.81e-141	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IHEPNEOK_01782	3.08e-123	-	-	-	-	-	-	-	-
IHEPNEOK_01783	6.76e-180	-	-	-	-	-	-	-	-
IHEPNEOK_01784	3.4e-86	-	-	-	-	-	-	-	-
IHEPNEOK_01785	1.35e-97	-	-	-	-	-	-	-	-
IHEPNEOK_01786	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHEPNEOK_01787	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHEPNEOK_01788	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHEPNEOK_01789	2.21e-196	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHEPNEOK_01790	1.48e-82	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHEPNEOK_01791	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
IHEPNEOK_01792	1.7e-313	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHEPNEOK_01793	9.76e-257	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHEPNEOK_01794	2.22e-50	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
IHEPNEOK_01795	2.02e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHEPNEOK_01796	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHEPNEOK_01797	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHEPNEOK_01798	1.21e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IHEPNEOK_01799	1.79e-126	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHEPNEOK_01800	1.61e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHEPNEOK_01801	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IHEPNEOK_01802	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
IHEPNEOK_01803	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IHEPNEOK_01804	4.91e-287	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
IHEPNEOK_01805	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
IHEPNEOK_01806	4.46e-90	-	-	-	-	-	-	-	-
IHEPNEOK_01808	3.24e-157	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
IHEPNEOK_01810	4.9e-91	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_01811	5.82e-145	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
IHEPNEOK_01812	1.32e-178	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IHEPNEOK_01813	1.91e-243	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IHEPNEOK_01815	3.6e-35	-	-	-	-	-	-	-	-
IHEPNEOK_01816	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K06147,ko:K11085,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IHEPNEOK_01817	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
IHEPNEOK_01818	6.96e-30	-	-	-	-	-	-	-	-
IHEPNEOK_01820	2.7e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01821	6.26e-170	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
IHEPNEOK_01823	0.0	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
IHEPNEOK_01824	2.85e-15	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IHEPNEOK_01825	8.13e-38	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IHEPNEOK_01826	2.89e-120	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
IHEPNEOK_01827	1.53e-18	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
IHEPNEOK_01829	1.69e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
IHEPNEOK_01830	1.59e-117	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
IHEPNEOK_01831	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
IHEPNEOK_01832	2.54e-131	-	-	-	T	-	-	-	integral membrane protein
IHEPNEOK_01833	1.33e-110	-	-	-	S	-	-	-	YcxB-like protein
IHEPNEOK_01834	1.89e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
IHEPNEOK_01835	2.58e-11	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
IHEPNEOK_01836	2.33e-75	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
IHEPNEOK_01837	3.62e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
IHEPNEOK_01839	3.68e-190	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
IHEPNEOK_01840	3.18e-88	-	-	-	T	-	-	-	domain protein
IHEPNEOK_01841	4.02e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
IHEPNEOK_01842	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHEPNEOK_01843	4.45e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
IHEPNEOK_01844	7.39e-65	-	-	-	-	-	-	-	-
IHEPNEOK_01845	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
IHEPNEOK_01847	4.36e-84	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
IHEPNEOK_01849	1.44e-36	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHEPNEOK_01850	1.56e-61	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
IHEPNEOK_01851	1.77e-71	-	-	-	O	-	-	-	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
IHEPNEOK_01852	2.71e-233	-	-	-	S	-	-	-	AAA domain
IHEPNEOK_01853	8.76e-104	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHEPNEOK_01854	2.61e-161	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHEPNEOK_01855	8.57e-41	-	-	-	-	-	-	-	-
IHEPNEOK_01856	2.88e-39	-	-	-	-	-	-	-	-
IHEPNEOK_01857	5.92e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
IHEPNEOK_01858	1.49e-157	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IHEPNEOK_01859	2.77e-140	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
IHEPNEOK_01860	7.52e-121	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IHEPNEOK_01861	2.03e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IHEPNEOK_01863	1.29e-24	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
IHEPNEOK_01864	9.02e-177	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
IHEPNEOK_01865	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
IHEPNEOK_01866	9.91e-59	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHEPNEOK_01867	9.82e-213	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHEPNEOK_01868	3.01e-11	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
IHEPNEOK_01869	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
IHEPNEOK_01870	3.37e-195	-	-	-	D	-	-	-	nuclear chromosome segregation
IHEPNEOK_01871	2.41e-128	-	-	-	M	-	-	-	LysM domain protein
IHEPNEOK_01875	3.72e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHEPNEOK_01876	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
IHEPNEOK_01880	5.93e-129	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IHEPNEOK_01881	3.2e-137	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
IHEPNEOK_01882	3.18e-34	-	-	-	-	-	-	-	-
IHEPNEOK_01883	1.52e-175	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
IHEPNEOK_01884	6.12e-199	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IHEPNEOK_01885	1.86e-103	-	2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHEPNEOK_01886	1.1e-254	-	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHEPNEOK_01887	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IHEPNEOK_01888	1.96e-158	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IHEPNEOK_01889	4.71e-98	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IHEPNEOK_01890	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
IHEPNEOK_01891	0.0	-	-	-	E	-	-	-	Amino acid permease
IHEPNEOK_01892	1.72e-44	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01893	1.37e-259	-	-	-	G	-	-	-	Major Facilitator Superfamily
IHEPNEOK_01894	3.21e-48	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
IHEPNEOK_01895	2.3e-265	-	-	-	G	-	-	-	Major Facilitator Superfamily
IHEPNEOK_01896	2.83e-207	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
IHEPNEOK_01898	5.21e-91	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHEPNEOK_01899	1.2e-126	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHEPNEOK_01900	2.09e-25	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
IHEPNEOK_01901	2.95e-283	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
IHEPNEOK_01904	3.39e-63	-	-	-	-	-	-	-	-
IHEPNEOK_01905	0.0	-	-	-	L	-	-	-	Helicase conserved C-terminal domain
IHEPNEOK_01906	4.74e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IHEPNEOK_01907	4.15e-10	-	-	-	K	-	-	-	Helix-turn-helix domain
IHEPNEOK_01909	2.01e-208	-	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
IHEPNEOK_01910	1.63e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
IHEPNEOK_01911	2.13e-07	-	-	-	-	-	-	-	-
IHEPNEOK_01912	1.64e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
IHEPNEOK_01913	2.27e-217	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
IHEPNEOK_01914	1.73e-179	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
IHEPNEOK_01915	1.16e-239	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
IHEPNEOK_01916	3.11e-143	-	-	-	L	-	-	-	DDE superfamily endonuclease
IHEPNEOK_01918	2.53e-97	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
IHEPNEOK_01919	9.06e-316	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
IHEPNEOK_01921	1.16e-256	-	-	-	S	-	-	-	amidohydrolase
IHEPNEOK_01922	1.5e-08	XK27_07210	-	-	S	-	-	-	B3 4 domain
IHEPNEOK_01923	1.73e-157	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IHEPNEOK_01924	1.19e-106	-	-	-	E	ko:K03758	-	ko00000,ko02000	amino acid
IHEPNEOK_01951	1.15e-278	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
IHEPNEOK_01952	1.06e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
IHEPNEOK_01953	3.8e-228	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHEPNEOK_01954	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHEPNEOK_01955	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
IHEPNEOK_01956	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHEPNEOK_01957	5.92e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHEPNEOK_01960	1.23e-275	-	-	-	S	-	-	-	FtsX-like permease family
IHEPNEOK_01961	1.96e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IHEPNEOK_01963	3.14e-297	-	-	-	L	-	-	-	Transposase
IHEPNEOK_01964	9.11e-118	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IHEPNEOK_01965	4.65e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
IHEPNEOK_01966	2.93e-280	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
IHEPNEOK_01967	4.39e-286	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHEPNEOK_01968	2.66e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
IHEPNEOK_01969	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
IHEPNEOK_01970	1.01e-104	cydD1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
IHEPNEOK_01972	3.92e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHEPNEOK_01973	4.68e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IHEPNEOK_01974	6.61e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHEPNEOK_01975	8.58e-220	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHEPNEOK_01976	9.04e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHEPNEOK_01977	1.29e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHEPNEOK_01978	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IHEPNEOK_01979	1.29e-235	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHEPNEOK_01980	1.04e-45	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IHEPNEOK_01981	2.71e-182	-	-	-	K	-	-	-	LysR family
IHEPNEOK_01982	9.07e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IHEPNEOK_01983	3.97e-246	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IHEPNEOK_01984	4.85e-15	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IHEPNEOK_01985	1.23e-16	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IHEPNEOK_01986	1.86e-35	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHEPNEOK_01987	1.13e-14	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	MafB19-like deaminase
IHEPNEOK_01993	1.03e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IHEPNEOK_01994	8.38e-75	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
IHEPNEOK_01995	3.53e-61	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift