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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKIEFAHG_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKIEFAHG_00002	7.9e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKIEFAHG_00003	0.0	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKIEFAHG_00004	2.35e-117	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HKIEFAHG_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKIEFAHG_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKIEFAHG_00007	2.65e-108	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HKIEFAHG_00008	1.89e-278	-	-	-	V	-	-	-	VanZ like family
HKIEFAHG_00009	3.88e-207	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HKIEFAHG_00010	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKIEFAHG_00011	4.42e-307	-	-	-	EGP	-	-	-	Transporter major facilitator family protein
HKIEFAHG_00012	6.85e-218	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
HKIEFAHG_00013	1.39e-95	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKIEFAHG_00014	3.45e-68	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HKIEFAHG_00017	4.87e-187	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HKIEFAHG_00018	2.87e-101	-	-	-	-	-	-	-	-
HKIEFAHG_00019	6.65e-198	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HKIEFAHG_00020	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKIEFAHG_00021	2.44e-191	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKIEFAHG_00022	1.79e-214	-	-	-	-	-	-	-	-
HKIEFAHG_00023	5.12e-139	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKIEFAHG_00024	5.46e-136	-	-	-	-	-	-	-	-
HKIEFAHG_00025	3.27e-25	-	-	-	-	-	-	-	-
HKIEFAHG_00028	2.13e-75	-	-	-	S	-	-	-	MazG-like family
HKIEFAHG_00029	1.15e-31	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKIEFAHG_00031	2.53e-243	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HKIEFAHG_00032	2.61e-60	-	-	-	S	-	-	-	Type II restriction endonuclease EcoO109I
HKIEFAHG_00033	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00034	1.94e-143	-	-	-	-	-	-	-	-
HKIEFAHG_00035	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00036	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00037	1.06e-52	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKIEFAHG_00038	5.7e-30	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HKIEFAHG_00039	1.01e-86	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKIEFAHG_00040	1.46e-210	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKIEFAHG_00041	1.14e-30	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKIEFAHG_00042	6.38e-154	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
HKIEFAHG_00043	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HKIEFAHG_00044	4.75e-110	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
HKIEFAHG_00045	1.13e-26	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
HKIEFAHG_00046	1.92e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4234)
HKIEFAHG_00047	3.2e-118	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00048	1.86e-81	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00049	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HKIEFAHG_00050	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HKIEFAHG_00051	7.41e-289	-	-	-	G	-	-	-	MFS/sugar transport protein
HKIEFAHG_00052	9.15e-158	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKIEFAHG_00053	1.87e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKIEFAHG_00054	4.68e-314	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKIEFAHG_00055	3.01e-165	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HKIEFAHG_00056	7.3e-275	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKIEFAHG_00057	1.3e-48	-	-	-	-	-	-	-	-
HKIEFAHG_00058	3.58e-213	-	3.6.3.17	-	G	ko:K02056,ko:K10545	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00059	1.59e-71	-	-	-	-	-	-	-	-
HKIEFAHG_00060	2.57e-250	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKIEFAHG_00061	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
HKIEFAHG_00062	0.0	araB	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
HKIEFAHG_00063	1.14e-166	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
HKIEFAHG_00064	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HKIEFAHG_00065	4.08e-216	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HKIEFAHG_00066	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKIEFAHG_00067	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKIEFAHG_00068	2.06e-205	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00069	3.81e-86	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00070	2.9e-264	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKIEFAHG_00071	1.4e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HKIEFAHG_00072	3.73e-104	-	-	-	I	-	-	-	Sterol carrier protein
HKIEFAHG_00073	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKIEFAHG_00074	9.18e-49	-	-	-	-	-	-	-	-
HKIEFAHG_00075	4.47e-192	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HKIEFAHG_00076	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HKIEFAHG_00077	2.13e-46	crgA	-	-	D	-	-	-	Involved in cell division
HKIEFAHG_00078	1.4e-177	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKIEFAHG_00079	1.07e-285	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKIEFAHG_00080	7.93e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HKIEFAHG_00081	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKIEFAHG_00082	1.37e-248	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKIEFAHG_00083	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HKIEFAHG_00084	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKIEFAHG_00085	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HKIEFAHG_00086	2.44e-94	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HKIEFAHG_00087	1.83e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HKIEFAHG_00088	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKIEFAHG_00089	5.05e-161	-	-	-	EG	-	-	-	EamA-like transporter family
HKIEFAHG_00090	1.54e-271	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HKIEFAHG_00091	3.36e-77	-	-	-	-	-	-	-	-
HKIEFAHG_00092	1.39e-229	rrmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HKIEFAHG_00093	4.12e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HKIEFAHG_00094	4.74e-48	-	-	-	S	-	-	-	Transglycosylase associated protein
HKIEFAHG_00096	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HKIEFAHG_00097	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKIEFAHG_00098	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HKIEFAHG_00099	6.47e-149	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKIEFAHG_00100	0.0	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HKIEFAHG_00101	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKIEFAHG_00103	1.98e-232	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKIEFAHG_00104	6.74e-271	-	-	-	V	-	-	-	Beta-lactamase
HKIEFAHG_00105	8.61e-158	-	-	-	E	-	-	-	SOS response associated peptidase (SRAP)
HKIEFAHG_00106	4.63e-293	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HKIEFAHG_00107	2.14e-14	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKIEFAHG_00108	8.74e-69	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HKIEFAHG_00109	2.39e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKIEFAHG_00110	0.0	-	-	-	S	-	-	-	cellulose binding
HKIEFAHG_00111	1.87e-181	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKIEFAHG_00112	1.13e-111	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HKIEFAHG_00113	2.08e-244	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HKIEFAHG_00114	5.51e-206	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKIEFAHG_00115	1.43e-250	-	1.1.1.91	-	C	ko:K05882	-	ko00000,ko01000	Aldo/keto reductase family
HKIEFAHG_00116	2.27e-05	-	-	-	I	-	-	-	acetylesterase activity
HKIEFAHG_00117	0.0	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
HKIEFAHG_00118	1.47e-120	-	-	-	C	-	-	-	Flavodoxin
HKIEFAHG_00119	1.47e-51	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKIEFAHG_00120	1.97e-111	-	-	-	C	-	-	-	Flavodoxin
HKIEFAHG_00121	3.29e-189	-	-	-	GM	-	-	-	NmrA-like family
HKIEFAHG_00122	7.83e-262	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HKIEFAHG_00123	2.86e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HKIEFAHG_00124	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKIEFAHG_00125	8.45e-249	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKIEFAHG_00126	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKIEFAHG_00127	3.73e-224	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIEFAHG_00128	7.85e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIEFAHG_00129	2.82e-306	-	-	-	U	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKIEFAHG_00130	6.84e-210	livM	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKIEFAHG_00131	1.67e-202	-	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKIEFAHG_00132	6.62e-194	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00133	1.73e-287	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKIEFAHG_00134	1e-244	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKIEFAHG_00135	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HKIEFAHG_00136	0.0	-	-	-	G	-	-	-	Transporter major facilitator family protein
HKIEFAHG_00137	9.6e-144	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKIEFAHG_00138	6.55e-309	accBC3	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HKIEFAHG_00139	3.05e-234	-	-	-	S	-	-	-	Domain of unknown function (DUF4392)
HKIEFAHG_00140	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HKIEFAHG_00141	5.95e-121	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HKIEFAHG_00142	2.26e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HKIEFAHG_00144	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKIEFAHG_00145	1.53e-258	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKIEFAHG_00146	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HKIEFAHG_00147	3.67e-281	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKIEFAHG_00148	0.0	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HKIEFAHG_00149	2.28e-175	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
HKIEFAHG_00150	5.1e-240	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKIEFAHG_00151	2.49e-148	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HKIEFAHG_00152	3.02e-171	-	-	-	-	-	-	-	-
HKIEFAHG_00153	5.24e-34	-	-	-	-	-	-	-	-
HKIEFAHG_00154	0.0	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HKIEFAHG_00155	8.53e-172	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00156	1.42e-187	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKIEFAHG_00157	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HKIEFAHG_00159	5.82e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKIEFAHG_00160	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKIEFAHG_00161	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKIEFAHG_00162	1.08e-43	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
HKIEFAHG_00164	0.0	-	-	-	M	-	-	-	MacB-like periplasmic core domain
HKIEFAHG_00165	8.06e-96	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_00166	7.97e-137	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKIEFAHG_00167	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_00168	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKIEFAHG_00169	0.0	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKIEFAHG_00170	5.42e-158	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKIEFAHG_00171	6.76e-151	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKIEFAHG_00172	1.34e-98	-	-	-	-	-	-	-	-
HKIEFAHG_00173	1.16e-292	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKIEFAHG_00174	2.75e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00175	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKIEFAHG_00176	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HKIEFAHG_00177	2.58e-139	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
HKIEFAHG_00178	7.69e-171	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKIEFAHG_00179	0.0	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00180	2.93e-230	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HKIEFAHG_00181	6.48e-213	-	-	-	S	-	-	-	esterase of the alpha-beta hydrolase superfamily
HKIEFAHG_00182	9.61e-43	-	-	-	K	-	-	-	transcriptional regulator
HKIEFAHG_00183	6.61e-147	-	-	-	-	-	-	-	-
HKIEFAHG_00185	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HKIEFAHG_00186	7.53e-156	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKIEFAHG_00187	1.95e-301	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKIEFAHG_00188	1.79e-300	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HKIEFAHG_00189	6.28e-73	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HKIEFAHG_00190	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HKIEFAHG_00191	3.38e-51	-	-	-	K	-	-	-	sequence-specific DNA binding
HKIEFAHG_00192	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKIEFAHG_00193	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HKIEFAHG_00194	6.15e-183	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HKIEFAHG_00195	3.85e-69	-	-	-	S	-	-	-	granule-associated protein
HKIEFAHG_00196	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKIEFAHG_00197	3.02e-254	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKIEFAHG_00198	5.67e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKIEFAHG_00199	2.45e-168	-	-	-	-	-	-	-	-
HKIEFAHG_00200	5.22e-262	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HKIEFAHG_00201	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKIEFAHG_00202	7.25e-94	-	-	-	D	-	-	-	bacterial-type flagellum organization
HKIEFAHG_00203	2.01e-291	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HKIEFAHG_00204	3.09e-151	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HKIEFAHG_00205	3.93e-143	-	-	-	U	-	-	-	Type II secretion system (T2SS), protein F
HKIEFAHG_00206	4.93e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HKIEFAHG_00207	5.66e-74	-	-	-	U	-	-	-	TadE-like protein
HKIEFAHG_00208	6.12e-98	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HKIEFAHG_00209	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HKIEFAHG_00210	8.17e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKIEFAHG_00211	2.52e-173	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKIEFAHG_00212	5.79e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKIEFAHG_00213	2.38e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKIEFAHG_00214	1.7e-155	-	-	-	-	-	-	-	-
HKIEFAHG_00215	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKIEFAHG_00216	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HKIEFAHG_00217	2.86e-274	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Myo-inositol-1-phosphate synthase
HKIEFAHG_00219	4.9e-281	-	-	-	I	-	-	-	PAP2 superfamily
HKIEFAHG_00220	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKIEFAHG_00221	2.72e-142	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKIEFAHG_00222	1.16e-285	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKIEFAHG_00223	6.8e-181	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKIEFAHG_00224	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HKIEFAHG_00225	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HKIEFAHG_00226	3.43e-281	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HKIEFAHG_00227	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HKIEFAHG_00228	9.48e-83	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HKIEFAHG_00229	5.83e-255	-	-	-	S	-	-	-	Protein conserved in bacteria
HKIEFAHG_00230	1.74e-130	-	-	-	S	-	-	-	GtrA-like protein
HKIEFAHG_00231	2.38e-224	-	-	-	-	-	-	-	-
HKIEFAHG_00232	1.51e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKIEFAHG_00233	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKIEFAHG_00234	4.39e-81	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00235	1.24e-28	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_00236	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKIEFAHG_00239	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKIEFAHG_00240	1.96e-186	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HKIEFAHG_00241	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKIEFAHG_00242	8.41e-165	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKIEFAHG_00243	5.98e-55	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HKIEFAHG_00244	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HKIEFAHG_00245	4.71e-316	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKIEFAHG_00246	1.57e-202	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKIEFAHG_00247	1.02e-202	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HKIEFAHG_00248	2.54e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKIEFAHG_00250	3.07e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
HKIEFAHG_00251	1.65e-236	-	-	-	S	-	-	-	CAAX protease self-immunity
HKIEFAHG_00252	2.29e-186	-	-	-	M	-	-	-	Mechanosensitive ion channel
HKIEFAHG_00253	9.92e-149	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKIEFAHG_00254	5.91e-297	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00255	1.12e-209	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKIEFAHG_00256	1.27e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00257	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00258	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00259	3.96e-253	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HKIEFAHG_00260	3.36e-42	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HKIEFAHG_00261	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HKIEFAHG_00262	0.0	-	-	-	M	-	-	-	Spy0128-like isopeptide containing domain
HKIEFAHG_00263	1.17e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HKIEFAHG_00264	1.47e-203	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKIEFAHG_00265	7.44e-155	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKIEFAHG_00266	4.08e-62	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKIEFAHG_00267	8.95e-94	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKIEFAHG_00268	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00269	8.36e-283	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKIEFAHG_00270	1.62e-205	-	-	-	P	-	-	-	Cation efflux family
HKIEFAHG_00271	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKIEFAHG_00272	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKIEFAHG_00273	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HKIEFAHG_00274	6.62e-176	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HKIEFAHG_00275	1.08e-119	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKIEFAHG_00276	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HKIEFAHG_00277	3.18e-181	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKIEFAHG_00278	4.3e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKIEFAHG_00279	1.08e-144	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKIEFAHG_00280	1.03e-156	-	-	-	-	-	-	-	-
HKIEFAHG_00281	2.39e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKIEFAHG_00282	2.64e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HKIEFAHG_00283	1.73e-248	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HKIEFAHG_00284	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKIEFAHG_00285	8.13e-59	-	-	-	-	-	-	-	-
HKIEFAHG_00286	1.69e-174	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKIEFAHG_00287	2.59e-170	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKIEFAHG_00288	2.98e-313	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00289	3.86e-236	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HKIEFAHG_00292	4.94e-287	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mannose-6-phosphate isomerase
HKIEFAHG_00293	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKIEFAHG_00294	1.67e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKIEFAHG_00295	5.12e-175	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKIEFAHG_00296	5.07e-185	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKIEFAHG_00297	1.28e-229	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00298	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HKIEFAHG_00299	3.25e-155	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKIEFAHG_00300	5.31e-295	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HKIEFAHG_00301	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HKIEFAHG_00302	7.1e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKIEFAHG_00303	1.23e-52	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HKIEFAHG_00304	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKIEFAHG_00305	1.76e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKIEFAHG_00306	2.39e-295	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKIEFAHG_00308	5.51e-46	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKIEFAHG_00309	3.74e-204	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKIEFAHG_00310	3.53e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKIEFAHG_00311	2.3e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKIEFAHG_00312	8.38e-188	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKIEFAHG_00313	2.36e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HKIEFAHG_00314	4.06e-134	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKIEFAHG_00315	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HKIEFAHG_00316	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HKIEFAHG_00317	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
HKIEFAHG_00318	1.39e-102	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKIEFAHG_00320	4.41e-156	-	-	-	-	-	-	-	-
HKIEFAHG_00321	2.28e-238	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKIEFAHG_00322	2.28e-65	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKIEFAHG_00323	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKIEFAHG_00324	2.65e-128	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKIEFAHG_00325	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKIEFAHG_00326	2.7e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKIEFAHG_00327	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKIEFAHG_00328	2.38e-100	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HKIEFAHG_00329	7.35e-28	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKIEFAHG_00330	5.57e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HKIEFAHG_00331	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HKIEFAHG_00332	1.79e-288	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HKIEFAHG_00333	3.41e-193	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKIEFAHG_00334	2.7e-172	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKIEFAHG_00335	3.73e-192	-	-	-	D	-	-	-	nuclear chromosome segregation
HKIEFAHG_00336	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKIEFAHG_00337	8.35e-279	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKIEFAHG_00338	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKIEFAHG_00339	1.15e-305	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKIEFAHG_00340	2.15e-155	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKIEFAHG_00341	1.85e-280	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKIEFAHG_00342	1.32e-168	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKIEFAHG_00343	3.8e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HKIEFAHG_00344	2.63e-218	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKIEFAHG_00345	1.53e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HKIEFAHG_00346	1.51e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKIEFAHG_00347	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HKIEFAHG_00348	2.41e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKIEFAHG_00349	2.13e-114	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKIEFAHG_00350	9.38e-68	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKIEFAHG_00351	0.0	-	-	-	T	-	-	-	Forkhead associated domain
HKIEFAHG_00352	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HKIEFAHG_00353	2.19e-52	-	-	-	-	-	-	-	-
HKIEFAHG_00354	8.73e-132	-	-	-	NO	-	-	-	SAF
HKIEFAHG_00355	1.76e-43	-	-	-	S	-	-	-	Putative regulatory protein
HKIEFAHG_00356	1.84e-177	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HKIEFAHG_00357	1.59e-103	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKIEFAHG_00358	1.73e-257	-	-	-	-	-	-	-	-
HKIEFAHG_00359	4.55e-64	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKIEFAHG_00363	2.06e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HKIEFAHG_00364	2.74e-302	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKIEFAHG_00365	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HKIEFAHG_00366	4.15e-80	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HKIEFAHG_00367	7.49e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HKIEFAHG_00368	0.0	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKIEFAHG_00370	1e-243	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKIEFAHG_00371	3.01e-147	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HKIEFAHG_00372	1.73e-157	-	-	-	-	-	-	-	-
HKIEFAHG_00373	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKIEFAHG_00374	1.31e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKIEFAHG_00375	6.69e-97	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKIEFAHG_00376	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKIEFAHG_00377	1.65e-267	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HKIEFAHG_00378	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKIEFAHG_00379	3.9e-244	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_00380	3.06e-198	-	-	-	S	-	-	-	YwiC-like protein
HKIEFAHG_00381	6.58e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKIEFAHG_00382	1.06e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKIEFAHG_00383	3.41e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKIEFAHG_00384	1.79e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKIEFAHG_00385	2.32e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKIEFAHG_00386	6.95e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKIEFAHG_00387	2.68e-75	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKIEFAHG_00388	4.69e-176	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKIEFAHG_00389	1.15e-99	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKIEFAHG_00390	5.27e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKIEFAHG_00391	7.84e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKIEFAHG_00392	5.15e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKIEFAHG_00393	4.44e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKIEFAHG_00394	1.94e-136	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKIEFAHG_00395	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKIEFAHG_00396	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKIEFAHG_00397	6.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKIEFAHG_00398	5.96e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKIEFAHG_00399	6.25e-132	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKIEFAHG_00400	1.75e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HKIEFAHG_00401	3.98e-100	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKIEFAHG_00402	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKIEFAHG_00403	4.41e-131	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKIEFAHG_00404	4.86e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKIEFAHG_00405	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKIEFAHG_00406	1.17e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKIEFAHG_00407	1.73e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKIEFAHG_00408	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIEFAHG_00409	1.16e-92	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKIEFAHG_00410	6.34e-190	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKIEFAHG_00412	5.94e-208	-	-	-	-	-	-	-	-
HKIEFAHG_00413	6.28e-249	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKIEFAHG_00414	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKIEFAHG_00415	5.79e-122	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKIEFAHG_00416	5.82e-250	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKIEFAHG_00417	9.91e-302	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HKIEFAHG_00418	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKIEFAHG_00419	1.12e-128	-	-	-	-	-	-	-	-
HKIEFAHG_00420	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HKIEFAHG_00421	2.05e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKIEFAHG_00422	7.54e-240	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKIEFAHG_00424	2.27e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKIEFAHG_00425	1.69e-278	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKIEFAHG_00426	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HKIEFAHG_00427	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HKIEFAHG_00428	5.96e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HKIEFAHG_00429	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HKIEFAHG_00430	8.64e-163	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKIEFAHG_00431	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
HKIEFAHG_00432	0.0	pspC	-	-	KT	-	-	-	PspC domain
HKIEFAHG_00433	5.45e-146	-	-	-	-	-	-	-	-
HKIEFAHG_00434	2.09e-286	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKIEFAHG_00435	2.38e-168	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKIEFAHG_00436	1.71e-38	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HKIEFAHG_00438	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKIEFAHG_00439	1.71e-186	-	-	-	-	-	-	-	-
HKIEFAHG_00440	0.0	-	-	-	E	-	-	-	Phospholipase B
HKIEFAHG_00441	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKIEFAHG_00442	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
HKIEFAHG_00443	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
HKIEFAHG_00444	0.0	-	-	-	E	-	-	-	Amino acid permease
HKIEFAHG_00445	1.05e-101	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HKIEFAHG_00446	2.91e-179	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKIEFAHG_00447	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HKIEFAHG_00448	1.62e-84	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HKIEFAHG_00449	4.64e-159	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HKIEFAHG_00450	0.0	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HKIEFAHG_00451	2.41e-29	-	-	-	-	-	-	-	-
HKIEFAHG_00452	1.87e-288	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKIEFAHG_00453	4.13e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKIEFAHG_00454	2.42e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKIEFAHG_00455	1.91e-228	-	-	-	S	-	-	-	CHAP domain
HKIEFAHG_00456	1.42e-140	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HKIEFAHG_00457	8.87e-252	-	-	-	T	-	-	-	Universal stress protein family
HKIEFAHG_00458	1.07e-94	-	-	-	O	-	-	-	OsmC-like protein
HKIEFAHG_00459	1.12e-223	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKIEFAHG_00460	1.46e-170	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HKIEFAHG_00461	1.04e-129	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HKIEFAHG_00462	9.11e-256	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKIEFAHG_00463	5.36e-206	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKIEFAHG_00465	3.21e-245	-	-	-	S	-	-	-	DUF218 domain
HKIEFAHG_00466	1.78e-239	-	3.1.3.5	-	S	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase
HKIEFAHG_00467	1.95e-139	-	-	-	-	-	-	-	-
HKIEFAHG_00468	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
HKIEFAHG_00470	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2130)
HKIEFAHG_00471	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00472	1.89e-187	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HKIEFAHG_00473	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00474	7.2e-302	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00476	2.83e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HKIEFAHG_00477	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HKIEFAHG_00478	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00479	3.44e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKIEFAHG_00480	7.35e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKIEFAHG_00481	2.76e-80	-	-	-	-	-	-	-	-
HKIEFAHG_00482	8.48e-132	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HKIEFAHG_00484	5.97e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HKIEFAHG_00485	2.28e-260	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKIEFAHG_00486	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00487	7.36e-225	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HKIEFAHG_00488	4.97e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00489	2.41e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
HKIEFAHG_00493	5.74e-241	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKIEFAHG_00494	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HKIEFAHG_00495	2.55e-307	-	-	-	M	-	-	-	Glycosyl transferase family 21
HKIEFAHG_00496	1.78e-207	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00497	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKIEFAHG_00498	8.49e-301	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HKIEFAHG_00499	5e-274	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKIEFAHG_00500	2.77e-128	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKIEFAHG_00501	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKIEFAHG_00502	3.66e-186	folK	2.7.6.3, 4.1.2.25	-	H	ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKIEFAHG_00503	7.39e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HKIEFAHG_00504	4.03e-221	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HKIEFAHG_00505	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HKIEFAHG_00506	4.14e-91	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKIEFAHG_00507	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
HKIEFAHG_00508	6.02e-145	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKIEFAHG_00509	5.11e-184	-	-	-	-	-	-	-	-
HKIEFAHG_00511	4.11e-223	-	-	-	-	-	-	-	-
HKIEFAHG_00512	1.47e-47	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HKIEFAHG_00513	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HKIEFAHG_00514	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKIEFAHG_00515	2.63e-241	-	-	-	K	ko:K02529,ko:K17640	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HKIEFAHG_00516	1.02e-310	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter periplasmic binding protein YcjN precursor K02027
HKIEFAHG_00517	1.54e-246	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00518	1.07e-203	-	-	-	P	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00519	0.0	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKIEFAHG_00520	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HKIEFAHG_00521	3.21e-299	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HKIEFAHG_00522	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HKIEFAHG_00523	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HKIEFAHG_00524	8.6e-293	xylR	-	-	GK	-	-	-	ROK family
HKIEFAHG_00525	9.15e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HKIEFAHG_00526	9.55e-217	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKIEFAHG_00527	9.47e-225	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKIEFAHG_00528	2.61e-150	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HKIEFAHG_00529	1.04e-268	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HKIEFAHG_00530	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKIEFAHG_00531	1.09e-158	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HKIEFAHG_00532	1.72e-200	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKIEFAHG_00533	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HKIEFAHG_00534	7.39e-98	-	-	-	-	-	-	-	-
HKIEFAHG_00535	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKIEFAHG_00536	6.13e-174	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HKIEFAHG_00537	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HKIEFAHG_00538	1.78e-133	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKIEFAHG_00539	1.86e-165	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HKIEFAHG_00540	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HKIEFAHG_00541	6.33e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKIEFAHG_00542	1.57e-236	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HKIEFAHG_00543	1.65e-265	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKIEFAHG_00544	1.64e-298	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HKIEFAHG_00545	2.42e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HKIEFAHG_00546	3.74e-282	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HKIEFAHG_00547	1.36e-105	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKIEFAHG_00548	3.92e-213	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HKIEFAHG_00549	3.75e-215	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HKIEFAHG_00550	6.2e-208	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00551	2.6e-197	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00552	2.66e-231	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_00553	1.98e-164	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKIEFAHG_00554	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKIEFAHG_00555	2.61e-184	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HKIEFAHG_00556	6.41e-89	-	-	-	-	-	-	-	-
HKIEFAHG_00557	1.14e-175	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKIEFAHG_00558	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKIEFAHG_00559	7.86e-217	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00560	8.71e-201	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00561	4.99e-181	oppDF2	-	-	P	ko:K02031,ko:K02032,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00562	9.13e-180	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00563	3.07e-284	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKIEFAHG_00564	5.12e-243	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKIEFAHG_00565	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKIEFAHG_00566	1.01e-221	-	-	-	S	-	-	-	Protein conserved in bacteria
HKIEFAHG_00567	1.29e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKIEFAHG_00570	4.02e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HKIEFAHG_00571	1.14e-30	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HKIEFAHG_00573	3.78e-76	-	-	-	-	-	-	-	-
HKIEFAHG_00574	4.86e-84	-	-	-	-	-	-	-	-
HKIEFAHG_00575	7.91e-95	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKIEFAHG_00576	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
HKIEFAHG_00577	8.48e-81	-	-	-	S	-	-	-	Fic/DOC family
HKIEFAHG_00578	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HKIEFAHG_00579	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HKIEFAHG_00580	9.13e-119	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HKIEFAHG_00581	2.04e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKIEFAHG_00582	5.05e-190	-	-	-	S	-	-	-	3-oxo-5-alpha-steroid 4-dehydrogenase
HKIEFAHG_00583	3.3e-290	gldA	1.1.1.6	-	C	ko:K00005,ko:K08317	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HKIEFAHG_00584	8.52e-122	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKIEFAHG_00585	1.21e-129	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKIEFAHG_00586	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKIEFAHG_00587	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKIEFAHG_00588	6.68e-282	-	-	-	P	-	-	-	Citrate transporter
HKIEFAHG_00590	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKIEFAHG_00591	6.53e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKIEFAHG_00592	1.2e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKIEFAHG_00593	2.4e-93	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKIEFAHG_00594	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HKIEFAHG_00595	0.0	-	-	-	S	-	-	-	Putative esterase
HKIEFAHG_00596	2.74e-305	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKIEFAHG_00597	3.44e-251	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKIEFAHG_00598	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKIEFAHG_00599	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HKIEFAHG_00600	7.52e-95	-	-	-	-	-	-	-	-
HKIEFAHG_00601	9.81e-297	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HKIEFAHG_00602	1.21e-130	-	-	-	-	-	-	-	-
HKIEFAHG_00603	1.97e-116	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKIEFAHG_00604	1.97e-140	-	-	-	K	-	-	-	sequence-specific DNA binding
HKIEFAHG_00606	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00607	2.73e-162	-	-	-	-	-	-	-	-
HKIEFAHG_00608	2.77e-90	-	-	-	-	-	-	-	-
HKIEFAHG_00609	4.96e-139	-	-	-	-	-	-	-	-
HKIEFAHG_00610	4.93e-286	-	-	-	S	-	-	-	Short C-terminal domain
HKIEFAHG_00611	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HKIEFAHG_00612	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKIEFAHG_00613	8.01e-297	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKIEFAHG_00614	3.4e-300	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKIEFAHG_00615	2.78e-253	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKIEFAHG_00617	8.2e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKIEFAHG_00618	1.34e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKIEFAHG_00619	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKIEFAHG_00620	2.25e-294	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKIEFAHG_00621	1.07e-157	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKIEFAHG_00622	8.01e-123	-	-	-	-	-	-	-	-
HKIEFAHG_00623	7.02e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKIEFAHG_00624	1.34e-103	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKIEFAHG_00625	6.95e-306	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKIEFAHG_00626	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKIEFAHG_00627	5.67e-232	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKIEFAHG_00628	6.35e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKIEFAHG_00629	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HKIEFAHG_00630	4.74e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKIEFAHG_00631	8.72e-279	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKIEFAHG_00632	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HKIEFAHG_00633	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKIEFAHG_00634	1.06e-235	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKIEFAHG_00635	8.15e-110	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HKIEFAHG_00636	5.9e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKIEFAHG_00637	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HKIEFAHG_00638	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HKIEFAHG_00639	4.64e-220	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HKIEFAHG_00640	8.24e-41	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HKIEFAHG_00641	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HKIEFAHG_00642	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HKIEFAHG_00643	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HKIEFAHG_00644	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HKIEFAHG_00645	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HKIEFAHG_00647	1.09e-125	-	-	-	-	-	-	-	-
HKIEFAHG_00648	1.23e-230	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKIEFAHG_00649	1.13e-249	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKIEFAHG_00650	9.9e-116	-	-	-	-	-	-	-	-
HKIEFAHG_00651	1.98e-231	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKIEFAHG_00652	1.79e-246	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKIEFAHG_00653	1.57e-180	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKIEFAHG_00654	9.65e-114	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HKIEFAHG_00655	4.22e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKIEFAHG_00656	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKIEFAHG_00657	2.56e-56	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HKIEFAHG_00658	1.78e-202	-	-	-	-	-	-	-	-
HKIEFAHG_00659	4.23e-171	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HKIEFAHG_00660	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKIEFAHG_00661	1.15e-103	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKIEFAHG_00662	4.88e-266	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HKIEFAHG_00663	6.14e-178	-	-	-	-	-	-	-	-
HKIEFAHG_00664	1.7e-234	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKIEFAHG_00665	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HKIEFAHG_00666	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKIEFAHG_00667	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HKIEFAHG_00668	5.33e-294	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HKIEFAHG_00669	1.4e-189	-	-	-	S	ko:K06889	-	ko00000	Serine aminopeptidase, S33
HKIEFAHG_00670	1.1e-182	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HKIEFAHG_00671	1.51e-198	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKIEFAHG_00672	2.23e-142	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00673	1.1e-256	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_00674	1.25e-239	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKIEFAHG_00675	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HKIEFAHG_00676	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HKIEFAHG_00677	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKIEFAHG_00678	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HKIEFAHG_00679	8.63e-255	-	-	-	L	-	-	-	Transposase, Mutator family
HKIEFAHG_00681	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00682	2.23e-184	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00683	1.42e-85	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HKIEFAHG_00684	1.17e-93	yccF	-	-	S	-	-	-	Inner membrane component domain
HKIEFAHG_00685	7.88e-182	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKIEFAHG_00686	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HKIEFAHG_00687	7.3e-210	-	-	-	S	-	-	-	Aldo/keto reductase family
HKIEFAHG_00688	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_00689	2.94e-85	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKIEFAHG_00690	1.93e-172	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKIEFAHG_00691	1.3e-283	-	-	-	E	-	-	-	Aminotransferase class I and II
HKIEFAHG_00692	7.71e-193	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00693	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKIEFAHG_00694	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKIEFAHG_00695	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKIEFAHG_00696	5.3e-263	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKIEFAHG_00697	3.49e-143	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKIEFAHG_00698	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKIEFAHG_00699	1.07e-188	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HKIEFAHG_00700	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKIEFAHG_00701	6.92e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HKIEFAHG_00702	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HKIEFAHG_00703	7.53e-272	-	-	-	T	-	-	-	Histidine kinase
HKIEFAHG_00704	1.03e-55	-	-	-	-	-	-	-	-
HKIEFAHG_00705	6.74e-209	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
HKIEFAHG_00706	1.05e-287	ytrE	-	-	V	ko:K02003,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	lipoprotein transporter activity
HKIEFAHG_00707	2.66e-139	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKIEFAHG_00708	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00709	3.03e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_00710	2.42e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKIEFAHG_00711	1.8e-18	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKIEFAHG_00712	9.87e-217	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKIEFAHG_00713	3.65e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKIEFAHG_00714	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HKIEFAHG_00715	5.69e-190	-	-	-	-	-	-	-	-
HKIEFAHG_00716	1.64e-260	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKIEFAHG_00717	7.16e-278	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKIEFAHG_00718	5.02e-228	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKIEFAHG_00719	1.31e-305	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKIEFAHG_00720	5.7e-235	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKIEFAHG_00721	1.23e-119	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKIEFAHG_00722	8.47e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKIEFAHG_00723	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKIEFAHG_00724	2.15e-198	butA	1.1.1.100, 1.1.1.304, 1.1.1.76	-	IQ	ko:K00059,ko:K03366	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKIEFAHG_00725	3.62e-116	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKIEFAHG_00726	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKIEFAHG_00727	2.75e-261	-	-	-	L	-	-	-	Tetratricopeptide repeat
HKIEFAHG_00728	4.09e-248	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HKIEFAHG_00729	8.69e-185	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKIEFAHG_00730	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HKIEFAHG_00731	9.59e-152	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HKIEFAHG_00732	8.73e-236	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKIEFAHG_00733	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKIEFAHG_00734	3.85e-166	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKIEFAHG_00735	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HKIEFAHG_00736	4.6e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKIEFAHG_00737	3.59e-148	-	-	-	-	-	-	-	-
HKIEFAHG_00738	1.06e-171	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKIEFAHG_00739	2.27e-246	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKIEFAHG_00741	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKIEFAHG_00742	4.35e-94	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKIEFAHG_00743	6.21e-159	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HKIEFAHG_00744	3.21e-134	-	-	-	-	-	-	-	-
HKIEFAHG_00747	9.97e-94	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HKIEFAHG_00748	1.72e-206	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HKIEFAHG_00749	5.76e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKIEFAHG_00750	5.23e-213	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKIEFAHG_00751	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKIEFAHG_00752	2.36e-171	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HKIEFAHG_00753	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HKIEFAHG_00754	2.44e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKIEFAHG_00755	1.84e-146	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HKIEFAHG_00756	7.23e-202	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HKIEFAHG_00757	3.49e-118	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HKIEFAHG_00758	7.97e-251	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKIEFAHG_00760	1.79e-117	-	-	-	-	-	-	-	-
HKIEFAHG_00762	1.16e-81	-	-	-	-	-	-	-	-
HKIEFAHG_00763	1.13e-137	-	-	-	M	-	-	-	Peptidase family M23
HKIEFAHG_00764	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HKIEFAHG_00765	1.2e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HKIEFAHG_00766	2.97e-266	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HKIEFAHG_00768	1.53e-35	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HKIEFAHG_00769	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HKIEFAHG_00770	5.55e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKIEFAHG_00771	1.03e-208	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKIEFAHG_00772	2.5e-177	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKIEFAHG_00773	5.41e-172	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKIEFAHG_00774	1.16e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKIEFAHG_00775	5.59e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HKIEFAHG_00776	3.81e-294	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKIEFAHG_00777	7.65e-136	-	-	-	K	-	-	-	WHG domain
HKIEFAHG_00778	3.54e-149	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00779	4.44e-173	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKIEFAHG_00780	2.11e-178	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKIEFAHG_00781	6.65e-100	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKIEFAHG_00782	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKIEFAHG_00783	4.39e-148	-	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HKIEFAHG_00784	3.13e-11	-	-	-	-	-	-	-	-
HKIEFAHG_00785	0.00074	-	-	-	-	-	-	-	-
HKIEFAHG_00786	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKIEFAHG_00787	3.55e-206	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKIEFAHG_00788	4.78e-235	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKIEFAHG_00789	7.7e-157	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HKIEFAHG_00790	3.18e-55	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HKIEFAHG_00791	5.79e-201	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HKIEFAHG_00792	4.93e-141	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKIEFAHG_00793	2.38e-225	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKIEFAHG_00794	1.09e-63	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HKIEFAHG_00795	1.81e-197	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HKIEFAHG_00796	2.66e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HKIEFAHG_00797	2.48e-170	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKIEFAHG_00798	5.12e-91	-	-	-	-	-	-	-	-
HKIEFAHG_00799	3.58e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIEFAHG_00800	5e-88	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIEFAHG_00801	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKIEFAHG_00802	5.49e-82	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HKIEFAHG_00803	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HKIEFAHG_00804	2.35e-67	-	-	-	-	-	-	-	-
HKIEFAHG_00805	0.0	-	-	-	K	-	-	-	WYL domain
HKIEFAHG_00806	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKIEFAHG_00808	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKIEFAHG_00809	7.04e-186	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKIEFAHG_00810	3.45e-221	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKIEFAHG_00811	5.52e-37	-	-	-	-	-	-	-	-
HKIEFAHG_00812	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKIEFAHG_00813	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_00814	1.85e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKIEFAHG_00815	5.72e-283	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKIEFAHG_00816	2.2e-133	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKIEFAHG_00817	1.9e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HKIEFAHG_00818	1.2e-260	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKIEFAHG_00819	5.91e-141	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKIEFAHG_00820	6.75e-132	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKIEFAHG_00821	6.09e-175	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HKIEFAHG_00822	1.34e-240	pimA	2.4.1.345	GT4	M	ko:K08256	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKIEFAHG_00823	4.4e-247	htrB	2.3.1.265	-	M	ko:K22311	-	ko00000,ko01000	Bacterial lipid A biosynthesis acyltransferase
HKIEFAHG_00824	8.83e-151	pgsA1	2.7.8.11, 2.7.8.5	-	I	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HKIEFAHG_00825	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKIEFAHG_00826	3.74e-127	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HKIEFAHG_00828	5.2e-123	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKIEFAHG_00829	2.65e-32	-	-	-	-	-	-	-	-
HKIEFAHG_00835	4.49e-199	-	-	-	S	-	-	-	PAC2 family
HKIEFAHG_00836	1.67e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKIEFAHG_00837	2.17e-204	-	-	-	G	-	-	-	Fructosamine kinase
HKIEFAHG_00838	2.49e-279	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKIEFAHG_00839	2.8e-256	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKIEFAHG_00840	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HKIEFAHG_00841	9.8e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKIEFAHG_00842	3.06e-109	-	-	-	S	-	-	-	PFAM Pentapeptide repeats (8 copies)
HKIEFAHG_00843	4.1e-293	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K00841,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKIEFAHG_00844	1.01e-117	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HKIEFAHG_00845	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HKIEFAHG_00846	7.54e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKIEFAHG_00847	2.87e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HKIEFAHG_00848	2.06e-194	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKIEFAHG_00849	2.34e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HKIEFAHG_00850	2.67e-224	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKIEFAHG_00851	1.72e-224	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKIEFAHG_00852	1.28e-225	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HKIEFAHG_00853	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKIEFAHG_00854	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKIEFAHG_00856	2.31e-230	-	-	-	-	-	-	-	-
HKIEFAHG_00857	1.57e-127	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HKIEFAHG_00858	1.93e-157	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HKIEFAHG_00859	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKIEFAHG_00860	3.78e-249	-	-	-	P	-	-	-	Cation efflux family
HKIEFAHG_00861	3.09e-187	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKIEFAHG_00862	2.09e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKIEFAHG_00863	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKIEFAHG_00864	5e-140	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HKIEFAHG_00865	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HKIEFAHG_00866	7.4e-223	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKIEFAHG_00867	5.22e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKIEFAHG_00868	1.23e-243	-	-	-	S	-	-	-	Protein conserved in bacteria
HKIEFAHG_00869	9.71e-232	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HKIEFAHG_00870	1.2e-76	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKIEFAHG_00871	1.25e-66	-	-	-	L	-	-	-	NUDIX domain
HKIEFAHG_00872	6.8e-104	ypeA	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.87
HKIEFAHG_00873	5.35e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKIEFAHG_00874	8.93e-241	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKIEFAHG_00875	3.32e-202	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HKIEFAHG_00876	1.68e-225	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HKIEFAHG_00877	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKIEFAHG_00878	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HKIEFAHG_00879	6.91e-242	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKIEFAHG_00880	1.33e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
HKIEFAHG_00881	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HKIEFAHG_00882	2.47e-203	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKIEFAHG_00883	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKIEFAHG_00884	1.07e-127	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HKIEFAHG_00885	7.41e-254	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HKIEFAHG_00886	1.41e-203	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00887	2.02e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HKIEFAHG_00888	4.8e-114	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HKIEFAHG_00889	1.11e-103	-	-	-	-	-	-	-	-
HKIEFAHG_00890	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKIEFAHG_00891	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HKIEFAHG_00892	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKIEFAHG_00893	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKIEFAHG_00894	1.36e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKIEFAHG_00895	1.74e-179	-	-	-	S	-	-	-	UPF0126 domain
HKIEFAHG_00896	2.14e-289	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HKIEFAHG_00897	6.37e-139	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKIEFAHG_00898	2.54e-249	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HKIEFAHG_00899	0.0	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HKIEFAHG_00900	4.73e-62	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HKIEFAHG_00901	2.51e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HKIEFAHG_00902	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HKIEFAHG_00903	6.02e-232	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKIEFAHG_00904	0.0	corC	-	-	S	-	-	-	CBS domain
HKIEFAHG_00905	1.5e-134	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKIEFAHG_00906	1.28e-274	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HKIEFAHG_00907	2.19e-77	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HKIEFAHG_00908	7.71e-185	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKIEFAHG_00910	2.75e-211	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HKIEFAHG_00911	9.8e-171	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
HKIEFAHG_00912	2.43e-284	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKIEFAHG_00913	5.86e-121	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKIEFAHG_00914	3.17e-135	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKIEFAHG_00915	2.17e-305	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKIEFAHG_00916	8.04e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKIEFAHG_00917	8.08e-300	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HKIEFAHG_00918	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HKIEFAHG_00919	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKIEFAHG_00920	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKIEFAHG_00921	3.78e-73	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HKIEFAHG_00922	4.16e-236	pulA	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKIEFAHG_00923	2.25e-109	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HKIEFAHG_00924	7.78e-125	-	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKIEFAHG_00927	6.74e-281	-	-	-	-	-	-	-	-
HKIEFAHG_00928	1.49e-286	-	-	-	-	-	-	-	-
HKIEFAHG_00929	1.78e-105	-	-	-	-	-	-	-	-
HKIEFAHG_00930	2.23e-105	-	-	-	-	-	-	-	-
HKIEFAHG_00931	1.64e-242	-	-	-	-	-	-	-	-
HKIEFAHG_00932	2.03e-92	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HKIEFAHG_00933	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKIEFAHG_00934	1.45e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKIEFAHG_00936	2.13e-264	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKIEFAHG_00937	3.78e-112	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKIEFAHG_00938	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKIEFAHG_00939	6.54e-46	-	-	-	-	-	-	-	-
HKIEFAHG_00940	1.31e-84	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HKIEFAHG_00941	7.34e-165	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HKIEFAHG_00942	2.01e-81	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKIEFAHG_00943	3.61e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKIEFAHG_00944	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKIEFAHG_00945	8.71e-119	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKIEFAHG_00946	0.0	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HKIEFAHG_00947	1.5e-151	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKIEFAHG_00948	6.73e-26	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HKIEFAHG_00949	1.51e-226	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HKIEFAHG_00950	5.4e-239	-	-	-	K	-	-	-	TRANSCRIPTIONal
HKIEFAHG_00951	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HKIEFAHG_00952	1.07e-181	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HKIEFAHG_00953	1.63e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HKIEFAHG_00954	1.89e-133	-	-	-	S	-	-	-	ABC-2 family transporter protein
HKIEFAHG_00955	2.02e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00956	1.42e-86	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKIEFAHG_00957	5.23e-244	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKIEFAHG_00958	1.88e-214	add1	3.5.4.4	-	F	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKIEFAHG_00959	3.44e-182	-	-	-	-	-	-	-	-
HKIEFAHG_00960	1.23e-67	-	4.2.99.21	-	E	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Chorismate mutase type II
HKIEFAHG_00961	6.73e-207	-	-	-	E	-	-	-	-acetyltransferase
HKIEFAHG_00962	1.82e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKIEFAHG_00963	3.03e-140	-	-	-	F	-	-	-	adenylate kinase activity
HKIEFAHG_00964	8.85e-85	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HKIEFAHG_00965	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
HKIEFAHG_00966	5.18e-228	-	-	-	L	ko:K07481	-	ko00000	Transposase domain (DUF772)
HKIEFAHG_00967	4.41e-92	-	-	-	K	-	-	-	sequence-specific DNA binding
HKIEFAHG_00968	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKIEFAHG_00969	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HKIEFAHG_00970	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HKIEFAHG_00971	4.94e-297	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKIEFAHG_00972	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKIEFAHG_00974	1.05e-295	-	-	-	-	-	-	-	-
HKIEFAHG_00975	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKIEFAHG_00976	3.06e-158	-	-	-	L	-	-	-	NUDIX domain
HKIEFAHG_00977	3.04e-235	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HKIEFAHG_00978	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKIEFAHG_00980	7.75e-158	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HKIEFAHG_00981	6.77e-153	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKIEFAHG_00983	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HKIEFAHG_00984	5.79e-230	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HKIEFAHG_00985	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKIEFAHG_00986	1.4e-152	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKIEFAHG_00987	4.47e-315	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKIEFAHG_00988	3.33e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKIEFAHG_00989	1.26e-236	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKIEFAHG_00990	4.24e-217	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_00991	2.27e-185	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HKIEFAHG_00992	7.88e-116	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKIEFAHG_00993	1.02e-132	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HKIEFAHG_00994	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKIEFAHG_00995	3.21e-168	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HKIEFAHG_00996	8.38e-258	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKIEFAHG_00997	3.71e-187	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HKIEFAHG_00998	1.75e-197	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HKIEFAHG_00999	1.6e-72	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HKIEFAHG_01000	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_01001	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HKIEFAHG_01002	0.0	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKIEFAHG_01003	8.99e-234	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKIEFAHG_01004	1.17e-313	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HKIEFAHG_01005	5.33e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HKIEFAHG_01006	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKIEFAHG_01007	6.93e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HKIEFAHG_01008	3.4e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKIEFAHG_01009	2.24e-97	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HKIEFAHG_01010	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HKIEFAHG_01011	1.24e-136	-	-	-	-	-	-	-	-
HKIEFAHG_01013	2.94e-238	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HKIEFAHG_01014	2.96e-144	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HKIEFAHG_01015	3.48e-128	-	-	-	D	-	-	-	Septum formation initiator
HKIEFAHG_01016	8.66e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKIEFAHG_01017	3.38e-209	-	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01018	1.14e-224	-	-	-	P	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
HKIEFAHG_01019	3.28e-165	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_01021	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKIEFAHG_01022	3.18e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKIEFAHG_01023	7.24e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKIEFAHG_01024	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HKIEFAHG_01025	9.99e-300	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HKIEFAHG_01026	5.3e-22	-	-	-	S	-	-	-	Selenoprotein, putative
HKIEFAHG_01027	0.0	cstA	-	-	T	ko:K06200	-	ko00000	5TM C-terminal transporter carbon starvation CstA
HKIEFAHG_01028	2.88e-43	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKIEFAHG_01029	8.43e-94	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	(ABC) transporter
HKIEFAHG_01030	7.43e-130	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HKIEFAHG_01032	1.2e-116	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKIEFAHG_01033	3.72e-105	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKIEFAHG_01034	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKIEFAHG_01035	6.85e-54	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HKIEFAHG_01036	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKIEFAHG_01037	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKIEFAHG_01038	5.42e-232	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HKIEFAHG_01039	9.91e-189	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HKIEFAHG_01040	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKIEFAHG_01041	2.15e-22	M1-966	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKIEFAHG_01042	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKIEFAHG_01043	2.17e-247	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKIEFAHG_01044	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKIEFAHG_01045	1.53e-189	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKIEFAHG_01046	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HKIEFAHG_01047	2.85e-255	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKIEFAHG_01048	0.0	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HKIEFAHG_01049	1.66e-273	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HKIEFAHG_01050	5.55e-63	-	-	-	-	-	-	-	-
HKIEFAHG_01051	1.32e-76	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HKIEFAHG_01052	2.17e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKIEFAHG_01053	4.3e-186	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKIEFAHG_01054	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HKIEFAHG_01055	0.0	-	-	-	T	-	-	-	Histidine kinase
HKIEFAHG_01056	3.72e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKIEFAHG_01057	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKIEFAHG_01058	2.32e-219	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_01059	1.68e-136	ecfT	-	-	P	ko:K02008,ko:K16783,ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HKIEFAHG_01060	0.0	ykoD	-	-	P	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKIEFAHG_01062	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HKIEFAHG_01063	1.2e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKIEFAHG_01064	1.89e-114	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HKIEFAHG_01065	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HKIEFAHG_01066	1.44e-277	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HKIEFAHG_01067	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HKIEFAHG_01068	1.36e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HKIEFAHG_01069	2.13e-157	safC	-	-	S	-	-	-	O-methyltransferase
HKIEFAHG_01070	1.06e-192	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKIEFAHG_01071	0.0	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HKIEFAHG_01072	2.54e-311	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HKIEFAHG_01075	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKIEFAHG_01076	5.41e-160	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKIEFAHG_01077	3.08e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKIEFAHG_01078	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKIEFAHG_01079	6.03e-306	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKIEFAHG_01080	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HKIEFAHG_01081	6.98e-224	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKIEFAHG_01082	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKIEFAHG_01083	2.17e-43	-	-	-	-	-	-	-	-
HKIEFAHG_01084	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKIEFAHG_01085	1.09e-288	-	-	-	S	-	-	-	Peptidase dimerisation domain
HKIEFAHG_01086	3.75e-155	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01087	6.49e-304	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKIEFAHG_01088	2.68e-232	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HKIEFAHG_01089	4.86e-134	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKIEFAHG_01090	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKIEFAHG_01091	4.9e-108	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKIEFAHG_01092	1.42e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HKIEFAHG_01093	3.68e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HKIEFAHG_01094	9.9e-274	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKIEFAHG_01095	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HKIEFAHG_01096	9.5e-239	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
HKIEFAHG_01097	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HKIEFAHG_01098	2.31e-56	-	-	-	G	-	-	-	Major facilitator superfamily
HKIEFAHG_01100	5.36e-282	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKIEFAHG_01101	1.21e-288	-	2.4.1.345	GT4	M	ko:K08256	-	ko00000,ko01000,ko01003	Glycosyl transferase 4-like domain
HKIEFAHG_01102	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HKIEFAHG_01103	2.66e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKIEFAHG_01104	8.16e-167	-	-	-	-	-	-	-	-
HKIEFAHG_01105	7.37e-259	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKIEFAHG_01106	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HKIEFAHG_01107	1.73e-178	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKIEFAHG_01108	7.66e-127	-	-	-	-	-	-	-	-
HKIEFAHG_01109	3.49e-247	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKIEFAHG_01110	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKIEFAHG_01111	1.82e-160	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKIEFAHG_01113	2.43e-147	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HKIEFAHG_01114	6.98e-265	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKIEFAHG_01115	1.78e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HKIEFAHG_01116	2.75e-112	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKIEFAHG_01117	1.92e-144	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKIEFAHG_01118	8.42e-156	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKIEFAHG_01119	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HKIEFAHG_01120	4.34e-247	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKIEFAHG_01121	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKIEFAHG_01122	3.69e-184	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HKIEFAHG_01124	6.82e-254	-	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
HKIEFAHG_01125	3.98e-295	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKIEFAHG_01126	1.71e-301	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKIEFAHG_01127	1.62e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKIEFAHG_01128	2.19e-271	-	-	-	T	-	-	-	Histidine kinase
HKIEFAHG_01129	9.39e-149	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HKIEFAHG_01130	5.27e-195	-	-	-	S	-	-	-	Protein of unknown function DUF262
HKIEFAHG_01131	0.0	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_01132	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HKIEFAHG_01133	3.31e-158	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
HKIEFAHG_01134	3.99e-47	-	-	-	-	-	-	-	-
HKIEFAHG_01135	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKIEFAHG_01136	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKIEFAHG_01137	3.81e-133	-	-	-	-	-	-	-	-
HKIEFAHG_01138	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKIEFAHG_01139	2.68e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HKIEFAHG_01140	5.41e-204	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HKIEFAHG_01141	4.59e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HKIEFAHG_01142	2.11e-153	-	-	-	-	-	-	-	-
HKIEFAHG_01143	0.0	dppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKIEFAHG_01144	9.25e-220	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HKIEFAHG_01145	1.48e-199	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01146	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKIEFAHG_01147	1.44e-228	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKIEFAHG_01148	4.76e-190	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_01149	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKIEFAHG_01150	3.14e-54	-	-	-	-	-	-	-	-
HKIEFAHG_01151	7.85e-270	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HKIEFAHG_01152	6.3e-277	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HKIEFAHG_01153	4.3e-142	-	-	-	-	-	-	-	-
HKIEFAHG_01154	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HKIEFAHG_01155	0.0	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HKIEFAHG_01156	1.01e-200	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HKIEFAHG_01157	1.55e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HKIEFAHG_01158	9.9e-214	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HKIEFAHG_01159	1.63e-82	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKIEFAHG_01160	1.79e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HKIEFAHG_01161	2.25e-136	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKIEFAHG_01162	1.68e-193	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HKIEFAHG_01163	1.3e-264	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKIEFAHG_01164	3.2e-116	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKIEFAHG_01165	4.77e-229	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKIEFAHG_01166	3.12e-253	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKIEFAHG_01167	1.32e-72	-	-	-	-	-	-	-	-
HKIEFAHG_01168	2.85e-169	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HKIEFAHG_01169	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKIEFAHG_01170	2e-255	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HKIEFAHG_01171	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HKIEFAHG_01172	5.94e-149	-	-	-	KT	-	-	-	cheY-homologous receiver domain
HKIEFAHG_01173	2.34e-248	-	-	-	T	-	-	-	Histidine kinase
HKIEFAHG_01174	3.55e-192	-	-	-	-	-	-	-	-
HKIEFAHG_01175	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HKIEFAHG_01176	6.13e-127	-	-	-	F	-	-	-	NUDIX domain
HKIEFAHG_01177	1.51e-284	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKIEFAHG_01178	2.02e-217	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKIEFAHG_01179	6.33e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKIEFAHG_01180	3.23e-271	int8	-	-	L	-	-	-	Phage integrase family
HKIEFAHG_01182	0.00013	-	-	-	L	-	-	-	Helix-turn-helix domain
HKIEFAHG_01186	3.06e-39	-	-	-	-	-	-	-	-
HKIEFAHG_01187	4.49e-291	-	-	-	T	-	-	-	AAA domain
HKIEFAHG_01192	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HKIEFAHG_01195	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKIEFAHG_01196	3.5e-272	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01197	1.98e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01198	5.75e-76	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKIEFAHG_01199	3.14e-200	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKIEFAHG_01200	2.95e-301	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HKIEFAHG_01201	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKIEFAHG_01202	2.95e-206	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKIEFAHG_01203	0.0	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HKIEFAHG_01204	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKIEFAHG_01205	1.21e-267	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKIEFAHG_01206	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKIEFAHG_01207	9.34e-204	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKIEFAHG_01208	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HKIEFAHG_01209	3.19e-119	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HKIEFAHG_01210	2.11e-249	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKIEFAHG_01211	5.36e-111	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKIEFAHG_01212	0.0	-	-	-	L	-	-	-	DNA helicase
HKIEFAHG_01213	1.59e-289	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKIEFAHG_01214	1.85e-125	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKIEFAHG_01215	3.77e-14	-	-	-	M	-	-	-	LysM domain
HKIEFAHG_01216	1.06e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKIEFAHG_01217	2.23e-212	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKIEFAHG_01218	3.25e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKIEFAHG_01219	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKIEFAHG_01220	1.27e-150	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HKIEFAHG_01221	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HKIEFAHG_01222	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKIEFAHG_01223	1.28e-230	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HKIEFAHG_01224	3.66e-167	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HKIEFAHG_01225	2.09e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKIEFAHG_01226	4.58e-167	-	-	-	-	-	-	-	-
HKIEFAHG_01227	2.09e-143	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HKIEFAHG_01228	2.17e-287	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKIEFAHG_01229	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKIEFAHG_01230	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HKIEFAHG_01232	5.2e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKIEFAHG_01233	1.34e-127	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKIEFAHG_01234	7.28e-149	-	-	-	V	-	-	-	DivIVA protein
HKIEFAHG_01235	1.18e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKIEFAHG_01236	2.22e-103	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKIEFAHG_01237	7.23e-283	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKIEFAHG_01238	3.31e-316	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKIEFAHG_01239	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HKIEFAHG_01240	7.5e-125	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKIEFAHG_01241	0.0	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKIEFAHG_01242	7.04e-79	-	-	-	S	-	-	-	Thiamine-binding protein
HKIEFAHG_01243	3.28e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKIEFAHG_01244	9.04e-316	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HKIEFAHG_01245	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HKIEFAHG_01246	7.44e-190	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01247	3.8e-264	-	-	-	P	-	-	-	NMT1/THI5 like
HKIEFAHG_01248	4.16e-299	-	-	-	F	-	-	-	nucleoside hydrolase
HKIEFAHG_01250	5.72e-195	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKIEFAHG_01251	3.68e-170	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKIEFAHG_01252	0.0	-	-	-	I	-	-	-	acetylesterase activity
HKIEFAHG_01253	1.48e-291	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKIEFAHG_01254	5.92e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKIEFAHG_01255	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HKIEFAHG_01257	1.94e-105	-	-	-	-	-	-	-	-
HKIEFAHG_01258	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HKIEFAHG_01259	9.43e-233	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKIEFAHG_01260	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HKIEFAHG_01261	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKIEFAHG_01262	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HKIEFAHG_01263	1.45e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HKIEFAHG_01264	1.14e-213	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HKIEFAHG_01265	3.37e-156	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HKIEFAHG_01266	7.78e-223	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HKIEFAHG_01267	3.84e-186	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKIEFAHG_01268	1.21e-207	-	-	-	S	-	-	-	Patatin-like phospholipase
HKIEFAHG_01269	7.34e-197	hflK	-	-	O	-	-	-	prohibitin homologues
HKIEFAHG_01270	9.92e-211	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKIEFAHG_01271	2.41e-204	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HKIEFAHG_01272	3.77e-157	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01273	1.29e-145	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01274	2.49e-295	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKIEFAHG_01275	3.64e-142	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 9.99
HKIEFAHG_01276	3e-280	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKIEFAHG_01277	8.77e-208	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HKIEFAHG_01278	1.42e-244	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKIEFAHG_01279	1.07e-165	-	-	-	K	-	-	-	acetyltransferase
HKIEFAHG_01280	5.15e-134	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HKIEFAHG_01281	8.79e-10	-	-	-	-	-	-	-	-
HKIEFAHG_01284	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HKIEFAHG_01285	0.0	lysI	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HKIEFAHG_01286	1.13e-150	-	-	-	-	-	-	-	-
HKIEFAHG_01287	3.18e-41	-	-	-	-	-	-	-	-
HKIEFAHG_01288	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKIEFAHG_01289	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HKIEFAHG_01290	3.33e-149	pspA	-	-	KT	ko:K03969	-	ko00000	PspA/IM30 family
HKIEFAHG_01291	8.06e-315	-	-	-	S	-	-	-	COG1512 Beta-propeller domains of methanol dehydrogenase type
HKIEFAHG_01292	1.12e-08	-	-	-	L	-	-	-	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKIEFAHG_01293	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKIEFAHG_01294	3.48e-33	-	-	-	-	-	-	-	-
HKIEFAHG_01295	1.7e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKIEFAHG_01296	5.39e-62	-	-	-	-	-	-	-	-
HKIEFAHG_01297	2.3e-22	-	-	-	-	-	-	-	-
HKIEFAHG_01298	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKIEFAHG_01299	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_01300	6.41e-127	-	-	-	K	-	-	-	MarR family
HKIEFAHG_01301	2.28e-132	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKIEFAHG_01302	1.31e-129	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HKIEFAHG_01305	6.34e-66	-	-	-	-	-	-	-	-
HKIEFAHG_01306	4.02e-265	-	-	-	-	ko:K19133	-	ko00000,ko02048	-
HKIEFAHG_01307	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase Cas3
HKIEFAHG_01308	0.0	-	-	-	-	ko:K19132	-	ko00000,ko02048	-
HKIEFAHG_01309	5.26e-284	-	-	-	S	ko:K19131	-	ko00000,ko02048	CRISPR-associated protein GSU0053 (Cas_GSU0053)
HKIEFAHG_01310	7.49e-24	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR associated protein Cas2
HKIEFAHG_01311	0.0	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKIEFAHG_01312	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HKIEFAHG_01313	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HKIEFAHG_01314	8.85e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKIEFAHG_01315	5.83e-78	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKIEFAHG_01316	3.76e-183	-	-	-	-	-	-	-	-
HKIEFAHG_01317	2.07e-190	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKIEFAHG_01318	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HKIEFAHG_01319	1.04e-305	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKIEFAHG_01320	4.21e-60	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKIEFAHG_01321	7.29e-244	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HKIEFAHG_01323	5.11e-165	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HKIEFAHG_01324	2.09e-217	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HKIEFAHG_01325	1.34e-130	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HKIEFAHG_01326	0.0	-	-	-	S	-	-	-	zinc finger
HKIEFAHG_01327	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_01328	1.64e-162	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKIEFAHG_01329	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKIEFAHG_01330	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HKIEFAHG_01331	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKIEFAHG_01332	3.72e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKIEFAHG_01333	7.91e-173	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKIEFAHG_01334	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKIEFAHG_01335	2.04e-171	-	-	-	K	-	-	-	-acetyltransferase
HKIEFAHG_01336	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HKIEFAHG_01337	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKIEFAHG_01338	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HKIEFAHG_01339	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HKIEFAHG_01340	9.88e-163	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKIEFAHG_01341	3.4e-266	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKIEFAHG_01342	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HKIEFAHG_01343	5.62e-135	-	-	-	B	-	-	-	Belongs to the OprB family
HKIEFAHG_01344	1.49e-138	-	-	-	T	-	-	-	Forkhead associated domain
HKIEFAHG_01345	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIEFAHG_01346	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIEFAHG_01347	2.17e-68	-	-	-	-	-	-	-	-
HKIEFAHG_01348	5.51e-239	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HKIEFAHG_01349	3.3e-165	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKIEFAHG_01350	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKIEFAHG_01351	1.69e-57	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKIEFAHG_01352	1.45e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKIEFAHG_01354	3.52e-295	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HKIEFAHG_01355	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HKIEFAHG_01356	5.19e-184	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKIEFAHG_01357	9.89e-143	ppm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase family 2
HKIEFAHG_01358	2.16e-282	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HKIEFAHG_01359	2.6e-282	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HKIEFAHG_01360	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HKIEFAHG_01361	1.64e-178	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKIEFAHG_01362	5.28e-283	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKIEFAHG_01363	5.69e-105	-	-	-	J	-	-	-	TM2 domain
HKIEFAHG_01364	1.84e-28	-	-	-	-	-	-	-	-
HKIEFAHG_01365	1.06e-220	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKIEFAHG_01366	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HKIEFAHG_01367	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HKIEFAHG_01368	5.74e-94	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HKIEFAHG_01369	2.11e-273	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HKIEFAHG_01370	3.34e-220	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKIEFAHG_01371	1.17e-109	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HKIEFAHG_01372	1.18e-86	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HKIEFAHG_01373	3.66e-241	-	-	-	S	ko:K21688	-	ko00000	G5
HKIEFAHG_01374	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKIEFAHG_01375	1.57e-100	-	-	-	-	-	-	-	-
HKIEFAHG_01376	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HKIEFAHG_01377	3.45e-239	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01378	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
HKIEFAHG_01379	8.58e-218	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKIEFAHG_01380	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKIEFAHG_01381	1.28e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKIEFAHG_01382	4.52e-237	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01383	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKIEFAHG_01384	6.8e-219	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01385	4.03e-245	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
HKIEFAHG_01386	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_01387	6.81e-220	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HKIEFAHG_01388	9.26e-187	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKIEFAHG_01389	1.34e-210	-	-	GT2	S	ko:K12992	ko02025,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
HKIEFAHG_01390	3.61e-234	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HKIEFAHG_01391	5.09e-302	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HKIEFAHG_01392	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HKIEFAHG_01393	1.53e-252	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKIEFAHG_01394	4.92e-208	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01395	0.0	-	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKIEFAHG_01396	2.01e-65	-	-	-	-	-	-	-	-
HKIEFAHG_01397	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HKIEFAHG_01398	6.59e-310	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKIEFAHG_01399	1.3e-174	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HKIEFAHG_01400	2.31e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKIEFAHG_01401	1.24e-152	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKIEFAHG_01402	2.31e-135	-	-	-	M	-	-	-	epimerase dehydratase
HKIEFAHG_01403	6.41e-111	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HKIEFAHG_01404	1.84e-119	-	-	-	M	-	-	-	Glycosyltransferase family 28 C-terminal domain
HKIEFAHG_01405	6.67e-237	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01406	5.53e-205	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HKIEFAHG_01407	8.76e-261	-	-	-	S	-	-	-	EpsG family
HKIEFAHG_01408	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HKIEFAHG_01409	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HKIEFAHG_01410	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HKIEFAHG_01411	1.13e-132	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKIEFAHG_01412	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
HKIEFAHG_01413	0.0	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HKIEFAHG_01414	6.14e-110	-	-	-	-	-	-	-	-
HKIEFAHG_01415	0.0	tnpA	-	-	L	-	-	-	Transposase
HKIEFAHG_01416	6.14e-24	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
HKIEFAHG_01417	4.17e-236	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKIEFAHG_01418	1.26e-311	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKIEFAHG_01419	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKIEFAHG_01420	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKIEFAHG_01421	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
HKIEFAHG_01422	1.23e-86	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HKIEFAHG_01423	9.46e-144	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01424	2.42e-235	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase 36 superfamily, catalytic domain
HKIEFAHG_01426	1.96e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HKIEFAHG_01427	6.91e-235	-	-	-	-	-	-	-	-
HKIEFAHG_01428	9.9e-276	-	-	-	-	-	-	-	-
HKIEFAHG_01429	2.58e-223	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HKIEFAHG_01430	4.85e-180	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKIEFAHG_01431	1.28e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKIEFAHG_01432	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKIEFAHG_01433	1.72e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKIEFAHG_01434	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKIEFAHG_01435	7.19e-196	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKIEFAHG_01436	2.71e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKIEFAHG_01437	2.54e-42	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKIEFAHG_01438	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKIEFAHG_01439	1.61e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKIEFAHG_01440	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKIEFAHG_01441	6.66e-235	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKIEFAHG_01443	2.08e-270	-	-	-	-	-	-	-	-
HKIEFAHG_01444	5.62e-37	-	-	-	-	-	-	-	-
HKIEFAHG_01445	2.44e-86	-	-	-	-	-	-	-	-
HKIEFAHG_01446	9.79e-182	-	-	-	D	ko:K03466	-	ko00000,ko03036	ftsk spoiiie
HKIEFAHG_01447	8.16e-159	-	-	-	S	-	-	-	Plasmid replication protein
HKIEFAHG_01448	9.18e-49	-	-	-	-	-	-	-	-
HKIEFAHG_01449	1.39e-284	-	-	-	L	-	-	-	HNH endonuclease
HKIEFAHG_01450	1.17e-280	-	-	-	H	-	-	-	Adenine-specific methyltransferase EcoRI
HKIEFAHG_01451	2.89e-292	-	-	-	L	-	-	-	Phage integrase family
HKIEFAHG_01452	0.0	frc	2.8.3.15, 2.8.3.16	-	C	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKIEFAHG_01453	4.97e-276	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	hydrolase family 5
HKIEFAHG_01454	5.91e-222	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKIEFAHG_01455	0.0	oxc	4.1.1.8	-	EH	ko:K01577	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HKIEFAHG_01456	0.0	-	-	-	P	-	-	-	Voltage gated chloride channel
HKIEFAHG_01457	0.0	-	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	domain protein
HKIEFAHG_01458	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HKIEFAHG_01459	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HKIEFAHG_01460	3.01e-120	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKIEFAHG_01461	3.16e-197	-	-	-	-	-	-	-	-
HKIEFAHG_01462	1.67e-191	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HKIEFAHG_01463	4.39e-178	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKIEFAHG_01464	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKIEFAHG_01465	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKIEFAHG_01466	1e-135	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HKIEFAHG_01467	5.49e-83	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HKIEFAHG_01468	0.0	-	-	-	S	-	-	-	domain protein
HKIEFAHG_01469	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKIEFAHG_01470	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HKIEFAHG_01471	1.87e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HKIEFAHG_01472	7.27e-252	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKIEFAHG_01473	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKIEFAHG_01474	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKIEFAHG_01475	4.42e-34	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKIEFAHG_01476	8.48e-198	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKIEFAHG_01477	2.77e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKIEFAHG_01478	7.8e-196	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HKIEFAHG_01479	6.33e-148	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKIEFAHG_01480	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HKIEFAHG_01481	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKIEFAHG_01482	1.32e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HKIEFAHG_01483	4.56e-109	-	-	-	-	-	-	-	-
HKIEFAHG_01484	0.0	-	-	-	M	-	-	-	domain protein
HKIEFAHG_01485	0.0	-	-	-	Q	-	-	-	von Willebrand factor (vWF) type A domain
HKIEFAHG_01486	5.75e-244	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKIEFAHG_01487	3.91e-200	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKIEFAHG_01488	3.88e-251	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKIEFAHG_01489	7.1e-236	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
HKIEFAHG_01490	7.69e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKIEFAHG_01494	6.82e-174	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
HKIEFAHG_01495	3.61e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKIEFAHG_01496	1.06e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKIEFAHG_01497	1.77e-124	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HKIEFAHG_01498	5.36e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKIEFAHG_01499	8.13e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKIEFAHG_01500	9.03e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKIEFAHG_01501	0.0	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HKIEFAHG_01502	3.76e-218	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKIEFAHG_01503	4.45e-253	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKIEFAHG_01505	8.79e-10	-	-	-	-	-	-	-	-
HKIEFAHG_01511	8.21e-11	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HKIEFAHG_01512	1.05e-299	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKIEFAHG_01513	2.34e-266	amsE	-	-	M	-	-	-	Glycosyl transferase family 2
HKIEFAHG_01515	3.65e-253	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HKIEFAHG_01516	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKIEFAHG_01517	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HKIEFAHG_01518	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HKIEFAHG_01519	2.57e-226	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKIEFAHG_01520	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKIEFAHG_01521	2.61e-239	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
HKIEFAHG_01522	1.62e-78	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKIEFAHG_01523	3.31e-130	-	-	-	M	-	-	-	hydrolase, family 25
HKIEFAHG_01524	1.2e-172	-	-	-	-	-	-	-	-
HKIEFAHG_01525	0.0	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HKIEFAHG_01526	0.0	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKIEFAHG_01527	5.64e-194	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKIEFAHG_01528	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKIEFAHG_01530	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKIEFAHG_01531	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKIEFAHG_01532	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HKIEFAHG_01533	0.0	-	-	-	V	-	-	-	ABC transporter permease
HKIEFAHG_01534	4.6e-249	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKIEFAHG_01535	8.09e-195	-	-	-	T	ko:K06950	-	ko00000	HD domain
HKIEFAHG_01536	1.17e-217	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HKIEFAHG_01537	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKIEFAHG_01538	1.7e-235	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKIEFAHG_01539	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HKIEFAHG_01540	6.89e-166	-	-	-	-	-	-	-	-
HKIEFAHG_01541	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKIEFAHG_01542	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKIEFAHG_01543	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKIEFAHG_01544	2.01e-167	-	-	-	-	-	-	-	-
HKIEFAHG_01545	9.93e-94	-	-	-	-	-	-	-	-
HKIEFAHG_01546	3.49e-221	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKIEFAHG_01547	0.0	pmt	2.4.1.109	GT39	O	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	ko00000,ko00001,ko01000,ko01003	C-terminal four TMM region of protein-O-mannosyltransferase
HKIEFAHG_01548	1.2e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKIEFAHG_01549	2.12e-174	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKIEFAHG_01551	6.73e-176	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKIEFAHG_01552	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HKIEFAHG_01553	4.71e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKIEFAHG_01554	1.2e-166	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HKIEFAHG_01555	1.43e-119	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HKIEFAHG_01556	4.87e-238	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HKIEFAHG_01557	6.25e-132	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKIEFAHG_01558	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKIEFAHG_01560	4.59e-247	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_01561	8.73e-187	traX	-	-	S	-	-	-	TraX protein
HKIEFAHG_01562	1.55e-190	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HKIEFAHG_01563	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HKIEFAHG_01564	2.29e-226	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01565	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01566	5.8e-303	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKIEFAHG_01567	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HKIEFAHG_01568	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKIEFAHG_01569	3.35e-140	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HKIEFAHG_01570	1.7e-197	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKIEFAHG_01571	1.1e-199	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01572	4.41e-232	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_01574	8.24e-308	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKIEFAHG_01575	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HKIEFAHG_01576	1.4e-148	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HKIEFAHG_01577	4.02e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HKIEFAHG_01578	1.44e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
HKIEFAHG_01579	4.78e-59	-	-	-	-	-	-	-	-
HKIEFAHG_01580	3.96e-124	iolT	-	-	EGP	-	-	-	Major facilitator Superfamily
HKIEFAHG_01581	8.79e-10	-	-	-	-	-	-	-	-
HKIEFAHG_01588	0.0	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HKIEFAHG_01589	0.0	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HKIEFAHG_01590	2.59e-257	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HKIEFAHG_01591	2.72e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HKIEFAHG_01592	1.43e-284	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKIEFAHG_01593	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKIEFAHG_01595	2.78e-237	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKIEFAHG_01596	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HKIEFAHG_01597	3.43e-206	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01598	1.35e-238	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKIEFAHG_01599	1.66e-308	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKIEFAHG_01600	3e-296	-	-	-	GK	-	-	-	ROK family
HKIEFAHG_01601	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HKIEFAHG_01602	4.78e-110	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKIEFAHG_01603	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HKIEFAHG_01604	3.82e-232	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HKIEFAHG_01605	2.47e-253	-	-	-	D	-	-	-	nuclear chromosome segregation
HKIEFAHG_01606	5.78e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HKIEFAHG_01607	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKIEFAHG_01608	3.62e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKIEFAHG_01609	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HKIEFAHG_01610	6.27e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKIEFAHG_01611	1.41e-241	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HKIEFAHG_01612	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKIEFAHG_01613	3.47e-114	-	-	-	O	-	-	-	Thioredoxin
HKIEFAHG_01615	7.02e-285	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HKIEFAHG_01616	1.13e-208	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKIEFAHG_01617	1.44e-227	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKIEFAHG_01618	1.51e-145	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HKIEFAHG_01619	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HKIEFAHG_01620	1.51e-239	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HKIEFAHG_01621	0.0	-	-	-	-	-	-	-	-
HKIEFAHG_01622	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HKIEFAHG_01623	2.29e-228	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKIEFAHG_01624	0.0	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKIEFAHG_01625	2.2e-225	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HKIEFAHG_01626	1.82e-174	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKIEFAHG_01627	4.13e-122	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HKIEFAHG_01628	8.06e-234	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HKIEFAHG_01629	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family