ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHFCAHFK_00001 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_00002 1.75e-07 - - - K - - - transcriptional regulator
MHFCAHFK_00003 1.12e-273 - - - S - - - membrane
MHFCAHFK_00004 4.31e-105 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00005 2.6e-227 - - - S - - - Zinc finger, swim domain protein
MHFCAHFK_00006 2.06e-164 - - - S - - - Zinc finger, swim domain protein
MHFCAHFK_00007 5.7e-146 - - - GM - - - epimerase
MHFCAHFK_00008 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
MHFCAHFK_00009 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
MHFCAHFK_00010 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MHFCAHFK_00011 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHFCAHFK_00012 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHFCAHFK_00013 6.25e-130 tanA - - S - - - alpha beta
MHFCAHFK_00014 1.74e-84 tanA - - S - - - alpha beta
MHFCAHFK_00015 6.46e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHFCAHFK_00016 4.38e-102 - - - K - - - Transcriptional regulator
MHFCAHFK_00017 2.18e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MHFCAHFK_00018 4.44e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHFCAHFK_00019 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MHFCAHFK_00020 5.25e-233 - - - C - - - Zinc-binding dehydrogenase
MHFCAHFK_00021 6.08e-277 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MHFCAHFK_00022 1.02e-261 - - - - - - - -
MHFCAHFK_00023 2.13e-118 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_00024 6.04e-52 - - - P - - - Rhodanese Homology Domain
MHFCAHFK_00025 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MHFCAHFK_00026 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_00027 9.3e-206 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_00028 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHFCAHFK_00029 1.95e-292 - - - M - - - O-Antigen ligase
MHFCAHFK_00030 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHFCAHFK_00031 6.55e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHFCAHFK_00032 1.29e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHFCAHFK_00033 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHFCAHFK_00034 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
MHFCAHFK_00035 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHFCAHFK_00036 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHFCAHFK_00037 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHFCAHFK_00038 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
MHFCAHFK_00039 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
MHFCAHFK_00040 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MHFCAHFK_00041 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHFCAHFK_00042 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHFCAHFK_00043 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHFCAHFK_00044 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHFCAHFK_00045 2.1e-117 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHFCAHFK_00046 5.38e-249 - - - S - - - Helix-turn-helix domain
MHFCAHFK_00047 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHFCAHFK_00048 1.25e-39 - - - M - - - Lysin motif
MHFCAHFK_00049 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHFCAHFK_00050 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHFCAHFK_00051 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHFCAHFK_00052 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHFCAHFK_00053 5.96e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MHFCAHFK_00054 3.71e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHFCAHFK_00055 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHFCAHFK_00056 4.25e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHFCAHFK_00057 6.46e-109 - - - - - - - -
MHFCAHFK_00058 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00059 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHFCAHFK_00060 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHFCAHFK_00061 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
MHFCAHFK_00062 1.19e-208 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MHFCAHFK_00063 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MHFCAHFK_00064 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
MHFCAHFK_00065 1.62e-100 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHFCAHFK_00066 9.19e-222 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHFCAHFK_00067 0.0 qacA - - EGP - - - Major Facilitator
MHFCAHFK_00068 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
MHFCAHFK_00069 1.75e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHFCAHFK_00070 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
MHFCAHFK_00071 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
MHFCAHFK_00072 5.13e-292 XK27_05470 - - E - - - Methionine synthase
MHFCAHFK_00073 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHFCAHFK_00074 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHFCAHFK_00075 5.03e-178 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MHFCAHFK_00076 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHFCAHFK_00077 9.43e-317 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHFCAHFK_00078 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MHFCAHFK_00079 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHFCAHFK_00080 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHFCAHFK_00081 4.24e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHFCAHFK_00082 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHFCAHFK_00083 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHFCAHFK_00084 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHFCAHFK_00085 3.82e-228 - - - K - - - Transcriptional regulator
MHFCAHFK_00086 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MHFCAHFK_00087 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHFCAHFK_00088 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHFCAHFK_00089 1.07e-43 - - - S - - - YozE SAM-like fold
MHFCAHFK_00090 1.03e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
MHFCAHFK_00091 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHFCAHFK_00092 1.33e-303 - - - M - - - Glycosyl transferase family group 2
MHFCAHFK_00093 3.81e-64 - - - - - - - -
MHFCAHFK_00094 7.91e-305 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHFCAHFK_00095 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_00096 1.34e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHFCAHFK_00097 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHFCAHFK_00098 1.66e-249 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHFCAHFK_00099 2.44e-242 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MHFCAHFK_00100 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MHFCAHFK_00101 7.87e-289 - - - - - - - -
MHFCAHFK_00102 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MHFCAHFK_00103 7.79e-78 - - - - - - - -
MHFCAHFK_00104 2.79e-181 - - - - - - - -
MHFCAHFK_00105 2.14e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHFCAHFK_00106 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MHFCAHFK_00107 6.02e-166 yejC - - S - - - Protein of unknown function (DUF1003)
MHFCAHFK_00108 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MHFCAHFK_00110 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_00111 2.82e-190 - - - C - - - Domain of unknown function (DUF4931)
MHFCAHFK_00112 2.37e-65 - - - - - - - -
MHFCAHFK_00113 1.29e-15 - - - - - - - -
MHFCAHFK_00114 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
MHFCAHFK_00115 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
MHFCAHFK_00116 1.11e-205 - - - S - - - EDD domain protein, DegV family
MHFCAHFK_00117 1.97e-87 - - - K - - - Transcriptional regulator
MHFCAHFK_00118 0.0 FbpA - - K - - - Fibronectin-binding protein
MHFCAHFK_00119 2.42e-71 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00120 5.37e-117 - - - F - - - NUDIX domain
MHFCAHFK_00122 2.31e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MHFCAHFK_00123 8.49e-92 - - - S - - - LuxR family transcriptional regulator
MHFCAHFK_00124 7.51e-166 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MHFCAHFK_00126 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MHFCAHFK_00127 4.75e-144 - - - G - - - Phosphoglycerate mutase family
MHFCAHFK_00128 0.0 - - - S - - - Bacterial membrane protein, YfhO
MHFCAHFK_00129 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHFCAHFK_00130 2.83e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MHFCAHFK_00131 1.1e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHFCAHFK_00132 1.96e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHFCAHFK_00133 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHFCAHFK_00134 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MHFCAHFK_00135 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
MHFCAHFK_00136 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MHFCAHFK_00137 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
MHFCAHFK_00138 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
MHFCAHFK_00139 6.79e-249 - - - - - - - -
MHFCAHFK_00140 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_00141 5.46e-157 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHFCAHFK_00142 8.41e-97 XK27_05710 - - K - - - Acetyltransferase (GNAT) domain
MHFCAHFK_00143 1.44e-234 - - - V - - - LD-carboxypeptidase
MHFCAHFK_00144 1.95e-308 - - - M ko:K07273 - ko00000 hydrolase, family 25
MHFCAHFK_00145 2.08e-97 - - - K - - - Acetyltransferase (GNAT) domain
MHFCAHFK_00146 3.32e-265 mccF - - V - - - LD-carboxypeptidase
MHFCAHFK_00147 1.59e-254 - - - M - - - Glycosyltransferase, group 2 family protein
MHFCAHFK_00148 2.26e-95 - - - S - - - SnoaL-like domain
MHFCAHFK_00149 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHFCAHFK_00150 1.22e-306 - - - P - - - Major Facilitator Superfamily
MHFCAHFK_00151 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_00152 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHFCAHFK_00154 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHFCAHFK_00155 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
MHFCAHFK_00156 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHFCAHFK_00157 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MHFCAHFK_00158 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_00159 4.86e-235 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHFCAHFK_00160 2.58e-155 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_00161 2.81e-140 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_00162 1.31e-109 - - - T - - - Universal stress protein family
MHFCAHFK_00163 5.51e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHFCAHFK_00164 8.18e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_00165 9.85e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHFCAHFK_00167 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
MHFCAHFK_00168 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MHFCAHFK_00169 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHFCAHFK_00170 2.53e-107 ypmB - - S - - - protein conserved in bacteria
MHFCAHFK_00171 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHFCAHFK_00172 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MHFCAHFK_00173 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MHFCAHFK_00174 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MHFCAHFK_00175 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHFCAHFK_00176 3.76e-244 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHFCAHFK_00177 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHFCAHFK_00178 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MHFCAHFK_00179 1.68e-157 - - - S - - - Domain of unknown function (DUF4767)
MHFCAHFK_00180 5.54e-85 rsmF - - J - - - NOL1 NOP2 sun family protein
MHFCAHFK_00181 2.19e-240 rsmF - - J - - - NOL1 NOP2 sun family protein
MHFCAHFK_00182 1.57e-191 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHFCAHFK_00183 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MHFCAHFK_00184 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHFCAHFK_00185 2.12e-57 - - - - - - - -
MHFCAHFK_00186 1.52e-67 - - - - - - - -
MHFCAHFK_00187 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
MHFCAHFK_00188 1.22e-217 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MHFCAHFK_00189 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHFCAHFK_00190 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MHFCAHFK_00191 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHFCAHFK_00192 1.06e-53 - - - - - - - -
MHFCAHFK_00193 4e-40 - - - S - - - CsbD-like
MHFCAHFK_00194 2.22e-55 - - - S - - - transglycosylase associated protein
MHFCAHFK_00195 5.79e-21 - - - - - - - -
MHFCAHFK_00196 1.51e-48 - - - - - - - -
MHFCAHFK_00197 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
MHFCAHFK_00198 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
MHFCAHFK_00199 3.05e-99 - - - T - - - Belongs to the universal stress protein A family
MHFCAHFK_00200 4.98e-107 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MHFCAHFK_00201 2.05e-55 - - - - - - - -
MHFCAHFK_00202 3.16e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MHFCAHFK_00203 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MHFCAHFK_00204 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MHFCAHFK_00205 1.42e-39 - - - - - - - -
MHFCAHFK_00206 2.1e-71 - - - - - - - -
MHFCAHFK_00208 1.19e-13 - - - - - - - -
MHFCAHFK_00212 8.14e-47 - - - L - - - Pfam:Integrase_AP2
MHFCAHFK_00213 6.56e-193 - - - O - - - Band 7 protein
MHFCAHFK_00214 0.0 - - - EGP - - - Major Facilitator
MHFCAHFK_00215 1e-119 - - - K - - - transcriptional regulator
MHFCAHFK_00216 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHFCAHFK_00217 4.94e-114 ykhA - - I - - - Thioesterase superfamily
MHFCAHFK_00218 1.07e-206 - - - K - - - LysR substrate binding domain
MHFCAHFK_00219 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHFCAHFK_00220 1.01e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MHFCAHFK_00221 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MHFCAHFK_00222 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MHFCAHFK_00223 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHFCAHFK_00224 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MHFCAHFK_00225 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MHFCAHFK_00226 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHFCAHFK_00227 1.48e-46 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHFCAHFK_00228 1.36e-184 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHFCAHFK_00229 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHFCAHFK_00230 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MHFCAHFK_00231 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHFCAHFK_00232 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHFCAHFK_00233 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHFCAHFK_00234 8.02e-230 yneE - - K - - - Transcriptional regulator
MHFCAHFK_00235 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_00236 2.47e-76 - - - S - - - Protein of unknown function (DUF1648)
MHFCAHFK_00237 3.01e-249 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHFCAHFK_00238 1.38e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
MHFCAHFK_00239 1.62e-276 - - - E - - - glutamate:sodium symporter activity
MHFCAHFK_00240 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
MHFCAHFK_00241 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MHFCAHFK_00242 1.45e-126 entB - - Q - - - Isochorismatase family
MHFCAHFK_00243 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHFCAHFK_00244 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHFCAHFK_00245 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MHFCAHFK_00246 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MHFCAHFK_00247 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHFCAHFK_00248 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
MHFCAHFK_00249 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
MHFCAHFK_00251 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHFCAHFK_00252 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHFCAHFK_00253 1.1e-112 - - - - - - - -
MHFCAHFK_00254 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHFCAHFK_00255 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHFCAHFK_00256 1.03e-66 - - - - - - - -
MHFCAHFK_00257 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHFCAHFK_00258 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHFCAHFK_00259 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHFCAHFK_00260 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHFCAHFK_00261 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHFCAHFK_00262 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHFCAHFK_00263 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHFCAHFK_00264 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHFCAHFK_00265 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHFCAHFK_00266 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHFCAHFK_00267 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHFCAHFK_00268 1.79e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHFCAHFK_00269 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHFCAHFK_00270 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MHFCAHFK_00271 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
MHFCAHFK_00272 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHFCAHFK_00273 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHFCAHFK_00274 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHFCAHFK_00275 9.9e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHFCAHFK_00276 4.21e-167 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHFCAHFK_00277 4.78e-272 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHFCAHFK_00278 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHFCAHFK_00279 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHFCAHFK_00280 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHFCAHFK_00281 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHFCAHFK_00282 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHFCAHFK_00283 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHFCAHFK_00284 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHFCAHFK_00285 2.38e-72 - - - - - - - -
MHFCAHFK_00286 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_00287 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHFCAHFK_00288 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_00289 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00290 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHFCAHFK_00291 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHFCAHFK_00292 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MHFCAHFK_00293 5.49e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHFCAHFK_00294 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHFCAHFK_00295 3.99e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHFCAHFK_00296 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHFCAHFK_00297 5.46e-89 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHFCAHFK_00298 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MHFCAHFK_00299 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHFCAHFK_00300 1e-247 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHFCAHFK_00301 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHFCAHFK_00302 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MHFCAHFK_00303 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHFCAHFK_00304 6.69e-124 - - - K - - - Transcriptional regulator
MHFCAHFK_00305 9.81e-27 - - - - - - - -
MHFCAHFK_00309 2.97e-41 - - - - - - - -
MHFCAHFK_00310 5.37e-74 - - - - - - - -
MHFCAHFK_00311 4.14e-126 - - - S - - - Protein conserved in bacteria
MHFCAHFK_00312 1.34e-232 - - - - - - - -
MHFCAHFK_00313 1.77e-205 - - - - - - - -
MHFCAHFK_00314 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHFCAHFK_00315 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MHFCAHFK_00316 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHFCAHFK_00317 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MHFCAHFK_00318 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MHFCAHFK_00319 1.15e-89 yqhL - - P - - - Rhodanese-like protein
MHFCAHFK_00320 6.61e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MHFCAHFK_00321 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHFCAHFK_00322 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MHFCAHFK_00323 2.47e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MHFCAHFK_00324 3.24e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHFCAHFK_00325 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHFCAHFK_00326 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHFCAHFK_00327 0.0 - - - S - - - membrane
MHFCAHFK_00328 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
MHFCAHFK_00329 5.72e-99 - - - K - - - LytTr DNA-binding domain
MHFCAHFK_00330 9.72e-146 - - - S - - - membrane
MHFCAHFK_00331 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHFCAHFK_00332 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHFCAHFK_00333 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHFCAHFK_00334 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHFCAHFK_00335 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHFCAHFK_00336 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MHFCAHFK_00337 1.41e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHFCAHFK_00338 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHFCAHFK_00339 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHFCAHFK_00340 6.89e-64 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHFCAHFK_00341 4.25e-120 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHFCAHFK_00342 1.21e-129 - - - S - - - SdpI/YhfL protein family
MHFCAHFK_00343 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHFCAHFK_00344 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MHFCAHFK_00345 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHFCAHFK_00346 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHFCAHFK_00347 1.38e-155 csrR - - K - - - response regulator
MHFCAHFK_00348 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHFCAHFK_00349 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHFCAHFK_00350 5.51e-39 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHFCAHFK_00351 1.27e-167 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHFCAHFK_00352 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
MHFCAHFK_00353 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MHFCAHFK_00354 3.55e-279 ylbM - - S - - - Belongs to the UPF0348 family
MHFCAHFK_00355 6.65e-180 yqeM - - Q - - - Methyltransferase
MHFCAHFK_00356 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHFCAHFK_00357 1.71e-149 yqeK - - H - - - Hydrolase, HD family
MHFCAHFK_00358 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHFCAHFK_00359 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MHFCAHFK_00360 2.1e-228 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MHFCAHFK_00361 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MHFCAHFK_00362 1.81e-113 - - - - - - - -
MHFCAHFK_00363 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MHFCAHFK_00364 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHFCAHFK_00365 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
MHFCAHFK_00366 6.92e-76 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHFCAHFK_00367 4.34e-156 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHFCAHFK_00368 8.2e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MHFCAHFK_00369 2.76e-74 - - - - - - - -
MHFCAHFK_00370 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHFCAHFK_00371 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHFCAHFK_00372 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHFCAHFK_00373 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHFCAHFK_00374 4.97e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHFCAHFK_00375 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MHFCAHFK_00376 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHFCAHFK_00377 3.88e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHFCAHFK_00378 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHFCAHFK_00379 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHFCAHFK_00380 3.46e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MHFCAHFK_00381 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MHFCAHFK_00382 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
MHFCAHFK_00383 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MHFCAHFK_00384 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MHFCAHFK_00385 1.83e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHFCAHFK_00386 8.63e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MHFCAHFK_00387 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MHFCAHFK_00388 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MHFCAHFK_00389 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MHFCAHFK_00390 3.04e-29 - - - S - - - Virus attachment protein p12 family
MHFCAHFK_00391 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHFCAHFK_00392 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHFCAHFK_00393 1.69e-144 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHFCAHFK_00394 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
MHFCAHFK_00395 1.92e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHFCAHFK_00396 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
MHFCAHFK_00397 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_00398 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00399 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MHFCAHFK_00400 7.9e-72 - - - - - - - -
MHFCAHFK_00401 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHFCAHFK_00402 1.35e-133 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00403 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00404 3.36e-248 - - - S - - - Fn3-like domain
MHFCAHFK_00405 4.75e-80 - - - - - - - -
MHFCAHFK_00406 0.0 - - - - - - - -
MHFCAHFK_00407 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MHFCAHFK_00408 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00409 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MHFCAHFK_00410 3.39e-138 - - - - - - - -
MHFCAHFK_00411 1.74e-135 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
MHFCAHFK_00412 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHFCAHFK_00413 2.08e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MHFCAHFK_00414 2.5e-110 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MHFCAHFK_00415 4.26e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHFCAHFK_00416 0.0 - - - S - - - membrane
MHFCAHFK_00417 2.24e-87 - - - S - - - NUDIX domain
MHFCAHFK_00418 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHFCAHFK_00419 3.85e-234 ykoT - - M - - - Glycosyl transferase family 2
MHFCAHFK_00420 0.0 - - - L - - - MutS domain V
MHFCAHFK_00421 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
MHFCAHFK_00422 4.09e-253 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHFCAHFK_00424 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MHFCAHFK_00425 1.81e-64 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MHFCAHFK_00426 6.28e-69 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MHFCAHFK_00427 7.13e-59 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MHFCAHFK_00429 3.33e-27 - - - M - - - domain protein
MHFCAHFK_00430 4.04e-62 - - - M - - - domain protein
MHFCAHFK_00431 1.97e-110 - - - S - - - Pfam:DUF3816
MHFCAHFK_00432 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHFCAHFK_00433 1.54e-144 - - - - - - - -
MHFCAHFK_00434 2.94e-227 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MHFCAHFK_00435 3.84e-185 - - - S - - - Peptidase_C39 like family
MHFCAHFK_00436 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
MHFCAHFK_00437 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHFCAHFK_00438 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
MHFCAHFK_00439 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHFCAHFK_00440 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MHFCAHFK_00441 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHFCAHFK_00442 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00443 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MHFCAHFK_00444 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MHFCAHFK_00445 3.55e-127 ywjB - - H - - - RibD C-terminal domain
MHFCAHFK_00446 2.3e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHFCAHFK_00447 1.05e-153 - - - S - - - Membrane
MHFCAHFK_00448 4.25e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
MHFCAHFK_00449 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MHFCAHFK_00450 3.46e-251 - - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_00451 4.35e-164 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHFCAHFK_00452 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHFCAHFK_00453 5.97e-106 - - - S - - - Domain of unknown function (DUF4811)
MHFCAHFK_00454 7.69e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHFCAHFK_00455 2.17e-222 - - - S - - - Conserved hypothetical protein 698
MHFCAHFK_00456 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_00457 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MHFCAHFK_00458 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_00460 2.72e-90 - - - M - - - LysM domain
MHFCAHFK_00461 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MHFCAHFK_00462 2.45e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00463 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHFCAHFK_00464 3.63e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_00465 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MHFCAHFK_00466 7.92e-99 yphH - - S - - - Cupin domain
MHFCAHFK_00467 7.37e-103 - - - K - - - transcriptional regulator, MerR family
MHFCAHFK_00468 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHFCAHFK_00469 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHFCAHFK_00470 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00472 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHFCAHFK_00473 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHFCAHFK_00474 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHFCAHFK_00475 2.82e-110 - - - - - - - -
MHFCAHFK_00476 5.14e-111 yvbK - - K - - - GNAT family
MHFCAHFK_00477 2.8e-49 - - - - - - - -
MHFCAHFK_00478 2.81e-64 - - - - - - - -
MHFCAHFK_00479 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
MHFCAHFK_00480 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
MHFCAHFK_00481 1.57e-202 - - - K - - - LysR substrate binding domain
MHFCAHFK_00482 2.53e-134 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00483 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHFCAHFK_00484 5.85e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_00485 1.2e-181 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MHFCAHFK_00486 5.63e-104 - - - S - - - Protein of unknown function (DUF1211)
MHFCAHFK_00487 2.14e-98 - - - C - - - Flavodoxin
MHFCAHFK_00488 7.97e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MHFCAHFK_00489 1.43e-114 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MHFCAHFK_00490 7.8e-113 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00491 2.11e-132 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MHFCAHFK_00492 5.63e-98 - - - K - - - Transcriptional regulator
MHFCAHFK_00494 9.48e-21 - - - C - - - Flavodoxin
MHFCAHFK_00495 2.83e-27 adhR - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_00496 8.2e-146 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_00497 8.04e-164 - - - C - - - Aldo keto reductase
MHFCAHFK_00498 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MHFCAHFK_00499 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MHFCAHFK_00500 5.64e-34 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00501 2.52e-38 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00502 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
MHFCAHFK_00503 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MHFCAHFK_00504 1.19e-160 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHFCAHFK_00505 1.07e-57 - - - - - - - -
MHFCAHFK_00506 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHFCAHFK_00507 3.45e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHFCAHFK_00508 1.52e-131 - - - M - - - Protein of unknown function (DUF3737)
MHFCAHFK_00509 4.96e-247 - - - C - - - Aldo/keto reductase family
MHFCAHFK_00511 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00512 6.9e-13 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00513 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00514 9.09e-314 - - - EGP - - - Major Facilitator
MHFCAHFK_00517 1.58e-230 yhgE - - V ko:K01421 - ko00000 domain protein
MHFCAHFK_00518 1.74e-123 - - - K - - - Transcriptional regulator (TetR family)
MHFCAHFK_00519 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_00520 3.34e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MHFCAHFK_00521 1.06e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MHFCAHFK_00522 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHFCAHFK_00523 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_00524 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MHFCAHFK_00525 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHFCAHFK_00526 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MHFCAHFK_00527 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MHFCAHFK_00528 2.33e-265 - - - EGP - - - Major facilitator Superfamily
MHFCAHFK_00529 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
MHFCAHFK_00530 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MHFCAHFK_00531 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MHFCAHFK_00532 2.85e-206 - - - I - - - alpha/beta hydrolase fold
MHFCAHFK_00533 1.01e-167 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MHFCAHFK_00534 0.0 - - - - - - - -
MHFCAHFK_00535 2e-52 - - - S - - - Cytochrome B5
MHFCAHFK_00536 3.54e-117 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHFCAHFK_00537 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
MHFCAHFK_00538 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
MHFCAHFK_00539 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHFCAHFK_00540 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MHFCAHFK_00541 1.56e-108 - - - - - - - -
MHFCAHFK_00542 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHFCAHFK_00543 1.59e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHFCAHFK_00544 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHFCAHFK_00545 3.7e-30 - - - - - - - -
MHFCAHFK_00546 1.84e-134 - - - - - - - -
MHFCAHFK_00547 5.12e-212 - - - K - - - LysR substrate binding domain
MHFCAHFK_00548 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
MHFCAHFK_00549 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MHFCAHFK_00550 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHFCAHFK_00551 2.79e-184 - - - S - - - zinc-ribbon domain
MHFCAHFK_00553 4.29e-50 - - - - - - - -
MHFCAHFK_00554 2.78e-176 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MHFCAHFK_00555 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHFCAHFK_00556 0.0 - - - I - - - acetylesterase activity
MHFCAHFK_00557 2.96e-296 - - - M - - - Collagen binding domain
MHFCAHFK_00558 6.92e-206 yicL - - EG - - - EamA-like transporter family
MHFCAHFK_00559 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
MHFCAHFK_00560 2.39e-225 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MHFCAHFK_00561 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
MHFCAHFK_00562 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
MHFCAHFK_00563 9.16e-208 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MHFCAHFK_00564 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHFCAHFK_00565 6.37e-125 - - - K - - - Transcriptional regulator, MarR family
MHFCAHFK_00566 2.71e-152 ydgI3 - - C - - - Nitroreductase family
MHFCAHFK_00567 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHFCAHFK_00568 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_00569 2.76e-196 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHFCAHFK_00570 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_00571 0.0 - - - - - - - -
MHFCAHFK_00572 3.08e-80 - - - - - - - -
MHFCAHFK_00573 7.52e-240 - - - S - - - Cell surface protein
MHFCAHFK_00574 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00575 1.04e-111 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MHFCAHFK_00576 1.61e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00577 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MHFCAHFK_00578 3.79e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHFCAHFK_00579 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHFCAHFK_00580 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MHFCAHFK_00582 2.32e-43 - - - - - - - -
MHFCAHFK_00583 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
MHFCAHFK_00584 2.88e-106 gtcA3 - - S - - - GtrA-like protein
MHFCAHFK_00585 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
MHFCAHFK_00586 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHFCAHFK_00587 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
MHFCAHFK_00588 7.03e-62 - - - - - - - -
MHFCAHFK_00589 1.81e-150 - - - S - - - SNARE associated Golgi protein
MHFCAHFK_00590 4.05e-09 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MHFCAHFK_00591 2.26e-123 - - - P - - - Cadmium resistance transporter
MHFCAHFK_00592 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00593 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
MHFCAHFK_00594 2.03e-84 - - - - - - - -
MHFCAHFK_00595 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHFCAHFK_00596 1.21e-73 - - - - - - - -
MHFCAHFK_00597 1.24e-194 - - - K - - - Helix-turn-helix domain
MHFCAHFK_00598 2.75e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHFCAHFK_00599 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_00600 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_00601 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_00602 1.57e-237 - - - GM - - - Male sterility protein
MHFCAHFK_00603 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_00604 4.61e-101 - - - M - - - LysM domain
MHFCAHFK_00605 1.44e-128 - - - M - - - Lysin motif
MHFCAHFK_00606 9.47e-137 - - - S - - - SdpI/YhfL protein family
MHFCAHFK_00607 1.58e-72 nudA - - S - - - ASCH
MHFCAHFK_00608 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHFCAHFK_00609 2.06e-119 - - - - - - - -
MHFCAHFK_00610 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
MHFCAHFK_00611 3.55e-281 - - - T - - - diguanylate cyclase
MHFCAHFK_00612 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
MHFCAHFK_00613 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MHFCAHFK_00614 1.58e-289 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
MHFCAHFK_00615 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MHFCAHFK_00616 4.63e-91 - - - - - - - -
MHFCAHFK_00617 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_00618 1.08e-221 - - - C - - - C4-dicarboxylate transmembrane transporter activity
MHFCAHFK_00619 2.15e-151 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00620 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MHFCAHFK_00621 6.7e-102 yphH - - S - - - Cupin domain
MHFCAHFK_00622 3.55e-79 - - - I - - - sulfurtransferase activity
MHFCAHFK_00623 3.3e-87 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
MHFCAHFK_00624 4.19e-70 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
MHFCAHFK_00625 8.38e-152 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00626 2.31e-277 - - - - - - - -
MHFCAHFK_00627 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00628 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00629 1.3e-226 - - - O - - - protein import
MHFCAHFK_00630 9.66e-292 amd - - E - - - Peptidase family M20/M25/M40
MHFCAHFK_00631 2.43e-208 yhxD - - IQ - - - KR domain
MHFCAHFK_00633 9.38e-91 - - - - - - - -
MHFCAHFK_00634 1.74e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
MHFCAHFK_00635 0.0 - - - E - - - Amino Acid
MHFCAHFK_00636 1.38e-85 lysM - - M - - - LysM domain
MHFCAHFK_00637 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
MHFCAHFK_00638 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MHFCAHFK_00639 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHFCAHFK_00640 3.01e-58 - - - S - - - Cupredoxin-like domain
MHFCAHFK_00641 1.36e-84 - - - S - - - Cupredoxin-like domain
MHFCAHFK_00642 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MHFCAHFK_00643 1.9e-179 - - - K - - - Helix-turn-helix domain
MHFCAHFK_00644 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
MHFCAHFK_00645 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHFCAHFK_00646 0.0 - - - - - - - -
MHFCAHFK_00647 1.56e-98 - - - - - - - -
MHFCAHFK_00648 1.11e-240 - - - S - - - Cell surface protein
MHFCAHFK_00649 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00650 9.33e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
MHFCAHFK_00651 7.09e-88 - - - S - - - Iron-sulphur cluster biosynthesis
MHFCAHFK_00652 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
MHFCAHFK_00653 1.59e-243 ynjC - - S - - - Cell surface protein
MHFCAHFK_00655 1.14e-129 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00656 5.61e-301 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MHFCAHFK_00657 4.13e-157 - - - - - - - -
MHFCAHFK_00658 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
MHFCAHFK_00659 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
MHFCAHFK_00660 6.03e-271 - - - EGP - - - Major Facilitator
MHFCAHFK_00661 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
MHFCAHFK_00662 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHFCAHFK_00663 8.01e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHFCAHFK_00664 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHFCAHFK_00665 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00666 5.35e-216 - - - GM - - - NmrA-like family
MHFCAHFK_00667 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHFCAHFK_00668 0.0 - - - M - - - Glycosyl hydrolases family 25
MHFCAHFK_00669 3.5e-30 - - - M - - - Glycosyl hydrolases family 25
MHFCAHFK_00670 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
MHFCAHFK_00671 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
MHFCAHFK_00672 3.27e-170 - - - S - - - KR domain
MHFCAHFK_00673 6.76e-125 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00674 5.76e-243 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
MHFCAHFK_00675 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
MHFCAHFK_00676 1.97e-229 ydhF - - S - - - Aldo keto reductase
MHFCAHFK_00677 0.0 yfjF - - U - - - Sugar (and other) transporter
MHFCAHFK_00678 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00679 3.49e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MHFCAHFK_00680 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHFCAHFK_00681 2.58e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFCAHFK_00682 1.35e-218 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFCAHFK_00683 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00684 2.52e-206 - - - GM - - - NmrA-like family
MHFCAHFK_00685 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_00686 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MHFCAHFK_00687 1.83e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_00688 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_00689 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHFCAHFK_00690 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHFCAHFK_00691 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
MHFCAHFK_00692 2.22e-115 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_00693 1.69e-195 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MHFCAHFK_00694 8.63e-72 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MHFCAHFK_00695 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00696 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHFCAHFK_00697 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MHFCAHFK_00698 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
MHFCAHFK_00699 1.16e-209 - - - K - - - LysR substrate binding domain
MHFCAHFK_00700 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHFCAHFK_00701 0.0 - - - S - - - MucBP domain
MHFCAHFK_00702 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MHFCAHFK_00703 1.85e-41 - - - - - - - -
MHFCAHFK_00705 6.07e-188 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHFCAHFK_00706 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_00707 0.0 - - - G ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757 ko00010,ko02060,map00010,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_00708 3.21e-87 - - - S - - - Protein of unknown function (DUF1093)
MHFCAHFK_00709 0.0 - 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHFCAHFK_00710 1.43e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHFCAHFK_00711 2.61e-64 sgaB 2.7.1.194, 2.7.1.200 - G ko:K02774,ko:K02822,ko:K03475 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MHFCAHFK_00712 1.63e-308 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_00713 1.32e-181 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_00714 2.73e-284 - - - S - - - Membrane
MHFCAHFK_00715 7.29e-60 - - - S - - - Protein of unknown function (DUF3781)
MHFCAHFK_00716 5.57e-141 yoaZ - - S - - - intracellular protease amidase
MHFCAHFK_00717 1.4e-57 - - - K - - - HxlR-like helix-turn-helix
MHFCAHFK_00718 8.95e-53 - - - C - - - Alcohol dehydrogenase GroES-like domain
MHFCAHFK_00719 5.64e-101 - - - C - - - Alcohol dehydrogenase GroES-like domain
MHFCAHFK_00720 5.49e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MHFCAHFK_00722 3.2e-109 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHFCAHFK_00723 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHFCAHFK_00724 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
MHFCAHFK_00725 2.31e-132 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MHFCAHFK_00726 4.71e-47 - - - S - - - aldo-keto reductase (NADP) activity
MHFCAHFK_00727 1.32e-139 - - - GM - - - NAD(P)H-binding
MHFCAHFK_00728 1.6e-103 - - - GM - - - SnoaL-like domain
MHFCAHFK_00729 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
MHFCAHFK_00730 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
MHFCAHFK_00731 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00732 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
MHFCAHFK_00733 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
MHFCAHFK_00735 1.37e-52 - - - - - - - -
MHFCAHFK_00736 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHFCAHFK_00737 9.26e-233 ydbI - - K - - - AI-2E family transporter
MHFCAHFK_00738 1.26e-268 xylR - - GK - - - ROK family
MHFCAHFK_00739 3.28e-147 - - - - - - - -
MHFCAHFK_00740 1.49e-294 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MHFCAHFK_00741 3.32e-210 - - - - - - - -
MHFCAHFK_00742 1.86e-256 pkn2 - - KLT - - - Protein tyrosine kinase
MHFCAHFK_00743 9.58e-35 - - - S - - - Protein of unknown function (DUF4064)
MHFCAHFK_00744 2e-71 - - - S - - - Domain of unknown function (DUF4352)
MHFCAHFK_00745 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
MHFCAHFK_00746 2.12e-72 - - - - - - - -
MHFCAHFK_00747 4.79e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
MHFCAHFK_00748 5.93e-73 - - - S - - - branched-chain amino acid
MHFCAHFK_00749 2.05e-167 - - - E - - - branched-chain amino acid
MHFCAHFK_00750 3.35e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MHFCAHFK_00751 1.26e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHFCAHFK_00752 5.61e-273 hpk31 - - T - - - Histidine kinase
MHFCAHFK_00753 1.14e-159 vanR - - K - - - response regulator
MHFCAHFK_00754 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
MHFCAHFK_00755 2.27e-112 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHFCAHFK_00756 1.63e-78 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHFCAHFK_00757 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHFCAHFK_00758 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
MHFCAHFK_00759 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHFCAHFK_00760 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MHFCAHFK_00761 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHFCAHFK_00762 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MHFCAHFK_00763 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHFCAHFK_00764 6.45e-131 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MHFCAHFK_00765 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MHFCAHFK_00766 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MHFCAHFK_00767 2.21e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_00768 3.36e-216 - - - K - - - LysR substrate binding domain
MHFCAHFK_00769 2.07e-302 - - - EK - - - Aminotransferase, class I
MHFCAHFK_00770 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHFCAHFK_00771 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_00772 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_00773 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_00774 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHFCAHFK_00775 1.12e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHFCAHFK_00776 4.68e-281 pbpX - - V - - - Beta-lactamase
MHFCAHFK_00777 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHFCAHFK_00778 2.9e-139 - - - - - - - -
MHFCAHFK_00779 7.62e-97 - - - - - - - -
MHFCAHFK_00781 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_00782 7.64e-316 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_00783 3.93e-99 - - - T - - - Universal stress protein family
MHFCAHFK_00785 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
MHFCAHFK_00786 1.94e-245 mocA - - S - - - Oxidoreductase
MHFCAHFK_00787 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MHFCAHFK_00788 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
MHFCAHFK_00789 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MHFCAHFK_00790 5.63e-196 gntR - - K - - - rpiR family
MHFCAHFK_00791 3.35e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_00792 2.88e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_00793 3.49e-216 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MHFCAHFK_00794 2.51e-308 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MHFCAHFK_00795 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00796 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHFCAHFK_00797 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MHFCAHFK_00798 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHFCAHFK_00799 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHFCAHFK_00800 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHFCAHFK_00801 3.86e-262 camS - - S - - - sex pheromone
MHFCAHFK_00802 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHFCAHFK_00803 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHFCAHFK_00804 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHFCAHFK_00805 3.79e-119 yebE - - S - - - UPF0316 protein
MHFCAHFK_00806 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHFCAHFK_00807 2.92e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MHFCAHFK_00808 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHFCAHFK_00809 4.04e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHFCAHFK_00810 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHFCAHFK_00811 1.55e-207 - - - S - - - L,D-transpeptidase catalytic domain
MHFCAHFK_00812 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MHFCAHFK_00813 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MHFCAHFK_00814 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MHFCAHFK_00815 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MHFCAHFK_00816 0.0 - - - S ko:K06889 - ko00000 Alpha beta
MHFCAHFK_00817 7.11e-32 - - - - - - - -
MHFCAHFK_00818 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
MHFCAHFK_00819 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MHFCAHFK_00820 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MHFCAHFK_00821 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MHFCAHFK_00822 6.5e-215 mleR - - K - - - LysR family
MHFCAHFK_00823 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
MHFCAHFK_00824 5.03e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MHFCAHFK_00825 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHFCAHFK_00826 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHFCAHFK_00827 3.38e-230 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MHFCAHFK_00828 3.88e-20 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MHFCAHFK_00830 6.87e-33 - - - K - - - sequence-specific DNA binding
MHFCAHFK_00831 5.69e-185 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MHFCAHFK_00832 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MHFCAHFK_00833 6.7e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MHFCAHFK_00834 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MHFCAHFK_00835 1.07e-241 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHFCAHFK_00836 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MHFCAHFK_00837 8.69e-230 citR - - K - - - sugar-binding domain protein
MHFCAHFK_00838 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHFCAHFK_00839 1.07e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHFCAHFK_00840 1.18e-66 - - - - - - - -
MHFCAHFK_00841 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHFCAHFK_00842 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHFCAHFK_00843 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHFCAHFK_00844 5.24e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MHFCAHFK_00845 6.33e-254 - - - K - - - Helix-turn-helix domain
MHFCAHFK_00846 1.72e-73 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MHFCAHFK_00847 7.76e-127 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MHFCAHFK_00848 2.01e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MHFCAHFK_00849 6.15e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
MHFCAHFK_00850 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHFCAHFK_00851 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHFCAHFK_00852 4.68e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
MHFCAHFK_00853 6.73e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHFCAHFK_00854 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHFCAHFK_00855 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MHFCAHFK_00856 5.79e-234 - - - S - - - Membrane
MHFCAHFK_00857 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MHFCAHFK_00858 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHFCAHFK_00859 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHFCAHFK_00860 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHFCAHFK_00861 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFCAHFK_00862 3.47e-212 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFCAHFK_00863 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFCAHFK_00864 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHFCAHFK_00865 3.19e-194 - - - S - - - FMN_bind
MHFCAHFK_00866 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHFCAHFK_00867 5.37e-112 - - - S - - - NusG domain II
MHFCAHFK_00868 1.65e-121 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MHFCAHFK_00869 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHFCAHFK_00870 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHFCAHFK_00871 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFCAHFK_00872 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHFCAHFK_00873 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHFCAHFK_00874 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHFCAHFK_00875 5.28e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHFCAHFK_00876 1.7e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHFCAHFK_00877 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHFCAHFK_00878 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHFCAHFK_00879 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHFCAHFK_00880 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHFCAHFK_00881 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHFCAHFK_00882 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHFCAHFK_00883 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHFCAHFK_00884 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHFCAHFK_00885 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHFCAHFK_00886 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHFCAHFK_00887 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHFCAHFK_00888 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHFCAHFK_00889 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHFCAHFK_00890 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHFCAHFK_00891 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHFCAHFK_00892 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHFCAHFK_00893 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHFCAHFK_00894 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHFCAHFK_00895 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHFCAHFK_00896 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHFCAHFK_00897 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHFCAHFK_00898 3.41e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHFCAHFK_00899 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHFCAHFK_00900 7.88e-145 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MHFCAHFK_00901 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFCAHFK_00902 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFCAHFK_00903 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_00904 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHFCAHFK_00905 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHFCAHFK_00913 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHFCAHFK_00914 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
MHFCAHFK_00915 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MHFCAHFK_00916 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MHFCAHFK_00917 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_00918 1.7e-118 - - - K - - - Transcriptional regulator
MHFCAHFK_00919 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHFCAHFK_00920 3.88e-198 - - - I - - - alpha/beta hydrolase fold
MHFCAHFK_00921 2.05e-153 - - - I - - - phosphatase
MHFCAHFK_00922 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHFCAHFK_00923 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
MHFCAHFK_00924 4.6e-169 - - - S - - - Putative threonine/serine exporter
MHFCAHFK_00925 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHFCAHFK_00926 7.39e-139 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MHFCAHFK_00927 1.36e-77 - - - - - - - -
MHFCAHFK_00928 7.79e-112 - - - K - - - MerR HTH family regulatory protein
MHFCAHFK_00929 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHFCAHFK_00930 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
MHFCAHFK_00931 1.46e-170 - - - - - - - -
MHFCAHFK_00932 1.75e-47 - - - K - - - MerR HTH family regulatory protein
MHFCAHFK_00933 1.43e-155 azlC - - E - - - branched-chain amino acid
MHFCAHFK_00934 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MHFCAHFK_00935 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHFCAHFK_00936 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MHFCAHFK_00937 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHFCAHFK_00938 0.0 xylP2 - - G - - - symporter
MHFCAHFK_00939 7.32e-247 - - - I - - - alpha/beta hydrolase fold
MHFCAHFK_00940 3.33e-64 - - - - - - - -
MHFCAHFK_00941 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
MHFCAHFK_00942 1.31e-129 - - - K - - - FR47-like protein
MHFCAHFK_00943 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
MHFCAHFK_00944 3.28e-278 yibE - - S - - - overlaps another CDS with the same product name
MHFCAHFK_00945 1.12e-243 - - - - - - - -
MHFCAHFK_00946 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
MHFCAHFK_00947 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_00948 1.36e-208 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHFCAHFK_00949 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHFCAHFK_00950 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
MHFCAHFK_00951 5.44e-56 - - - - - - - -
MHFCAHFK_00952 3.79e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MHFCAHFK_00954 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHFCAHFK_00955 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MHFCAHFK_00956 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MHFCAHFK_00957 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHFCAHFK_00958 4.3e-106 - - - K - - - Transcriptional regulator
MHFCAHFK_00960 0.0 - - - C - - - FMN_bind
MHFCAHFK_00961 1.37e-220 - - - K - - - Transcriptional regulator
MHFCAHFK_00962 1.88e-124 - - - K - - - Helix-turn-helix domain
MHFCAHFK_00963 1.06e-179 - - - K - - - sequence-specific DNA binding
MHFCAHFK_00964 4.17e-95 - - - S - - - AAA domain
MHFCAHFK_00965 1.42e-08 - - - - - - - -
MHFCAHFK_00966 0.0 - - - M - - - MucBP domain
MHFCAHFK_00967 3.28e-117 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MHFCAHFK_00968 3.37e-60 - - - S - - - MazG-like family
MHFCAHFK_00969 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MHFCAHFK_00970 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MHFCAHFK_00971 2.19e-131 - - - G - - - Glycogen debranching enzyme
MHFCAHFK_00972 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHFCAHFK_00973 4.25e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
MHFCAHFK_00974 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
MHFCAHFK_00975 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
MHFCAHFK_00976 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
MHFCAHFK_00977 5.74e-32 - - - - - - - -
MHFCAHFK_00978 1.95e-116 - - - - - - - -
MHFCAHFK_00979 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
MHFCAHFK_00980 0.0 XK27_09800 - - I - - - Acyltransferase family
MHFCAHFK_00981 3.61e-61 - - - S - - - MORN repeat
MHFCAHFK_00982 3.5e-299 - - - S - - - Cysteine-rich secretory protein family
MHFCAHFK_00983 1.92e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MHFCAHFK_00984 3.08e-74 - - - K - - - HxlR-like helix-turn-helix
MHFCAHFK_00985 1.16e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_00986 1.37e-83 - - - K - - - Helix-turn-helix domain
MHFCAHFK_00987 1.08e-71 - - - - - - - -
MHFCAHFK_00988 4.16e-97 - - - - - - - -
MHFCAHFK_00989 6.67e-30 - - - L ko:K07497 - ko00000 hmm pf00665
MHFCAHFK_00990 1.37e-37 - - - L ko:K07497 - ko00000 hmm pf00665
MHFCAHFK_00991 1.51e-22 - - - L ko:K07497 - ko00000 hmm pf00665
MHFCAHFK_00992 1.52e-59 - - - L - - - Helix-turn-helix domain
MHFCAHFK_00994 3.56e-171 spoVK - - O ko:K06413 - ko00000 ATPase family associated with various cellular activities (AAA)
MHFCAHFK_00996 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHFCAHFK_00997 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHFCAHFK_00998 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MHFCAHFK_00999 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHFCAHFK_01000 2.84e-146 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MHFCAHFK_01001 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MHFCAHFK_01002 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MHFCAHFK_01003 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
MHFCAHFK_01004 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
MHFCAHFK_01005 1.61e-36 - - - - - - - -
MHFCAHFK_01006 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MHFCAHFK_01007 1.88e-101 rppH3 - - F - - - NUDIX domain
MHFCAHFK_01008 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHFCAHFK_01009 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_01010 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
MHFCAHFK_01011 6.5e-269 - - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_01012 3.08e-93 - - - K - - - MarR family
MHFCAHFK_01013 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
MHFCAHFK_01014 2.55e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_01015 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
MHFCAHFK_01016 1.24e-179 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MHFCAHFK_01017 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHFCAHFK_01018 1.57e-196 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHFCAHFK_01019 1e-107 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHFCAHFK_01020 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01021 1.81e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01022 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHFCAHFK_01023 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01024 1.28e-54 - - - - - - - -
MHFCAHFK_01025 5.1e-218 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFCAHFK_01026 3.08e-266 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHFCAHFK_01027 2.83e-145 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
MHFCAHFK_01029 1.44e-188 - - - - - - - -
MHFCAHFK_01030 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MHFCAHFK_01031 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHFCAHFK_01032 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MHFCAHFK_01033 1.48e-27 - - - - - - - -
MHFCAHFK_01034 3.05e-95 - - - F - - - Nudix hydrolase
MHFCAHFK_01035 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MHFCAHFK_01036 6.12e-115 - - - - - - - -
MHFCAHFK_01037 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MHFCAHFK_01038 1.09e-60 - - - - - - - -
MHFCAHFK_01039 1.89e-90 - - - O - - - OsmC-like protein
MHFCAHFK_01040 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHFCAHFK_01041 0.0 oatA - - I - - - Acyltransferase
MHFCAHFK_01042 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHFCAHFK_01043 3.45e-231 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHFCAHFK_01044 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_01045 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHFCAHFK_01046 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_01047 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MHFCAHFK_01048 1.36e-27 - - - - - - - -
MHFCAHFK_01049 6.16e-107 - - - K - - - Transcriptional regulator
MHFCAHFK_01050 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MHFCAHFK_01051 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHFCAHFK_01052 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHFCAHFK_01053 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHFCAHFK_01054 1.06e-314 - - - EGP - - - Major Facilitator
MHFCAHFK_01055 2.08e-117 - - - V - - - VanZ like family
MHFCAHFK_01056 3.88e-46 - - - - - - - -
MHFCAHFK_01057 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
MHFCAHFK_01059 4.13e-182 - - - - - - - -
MHFCAHFK_01060 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHFCAHFK_01061 9.04e-49 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHFCAHFK_01062 7.34e-180 - - - EGP - - - Transmembrane secretion effector
MHFCAHFK_01063 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHFCAHFK_01064 2.05e-94 - - - - - - - -
MHFCAHFK_01065 3.38e-70 - - - - - - - -
MHFCAHFK_01066 1.7e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHFCAHFK_01067 7.01e-135 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_01068 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_01069 3.15e-158 - - - T - - - EAL domain
MHFCAHFK_01070 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHFCAHFK_01071 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHFCAHFK_01072 2.18e-182 ybbR - - S - - - YbbR-like protein
MHFCAHFK_01073 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHFCAHFK_01074 2.7e-154 - - - S - - - Protein of unknown function (DUF1361)
MHFCAHFK_01075 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_01076 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MHFCAHFK_01077 4.28e-169 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MHFCAHFK_01078 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MHFCAHFK_01079 1.46e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHFCAHFK_01080 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHFCAHFK_01081 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
MHFCAHFK_01082 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MHFCAHFK_01083 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MHFCAHFK_01084 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHFCAHFK_01085 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_01086 7.98e-137 - - - - - - - -
MHFCAHFK_01087 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01088 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_01089 8.34e-63 - - - M - - - Domain of unknown function (DUF5011)
MHFCAHFK_01090 0.0 - - - M - - - Domain of unknown function (DUF5011)
MHFCAHFK_01091 3.02e-126 - - - M - - - Domain of unknown function (DUF5011)
MHFCAHFK_01092 1.14e-20 - - - M - - - Domain of unknown function (DUF5011)
MHFCAHFK_01093 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHFCAHFK_01094 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHFCAHFK_01095 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MHFCAHFK_01096 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHFCAHFK_01097 0.0 eriC - - P ko:K03281 - ko00000 chloride
MHFCAHFK_01098 5.11e-171 - - - - - - - -
MHFCAHFK_01099 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHFCAHFK_01100 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHFCAHFK_01101 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHFCAHFK_01102 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHFCAHFK_01103 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MHFCAHFK_01104 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MHFCAHFK_01106 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHFCAHFK_01107 8.95e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFCAHFK_01108 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_01109 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHFCAHFK_01110 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHFCAHFK_01111 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHFCAHFK_01112 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
MHFCAHFK_01113 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHFCAHFK_01114 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHFCAHFK_01115 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHFCAHFK_01116 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHFCAHFK_01117 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHFCAHFK_01118 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MHFCAHFK_01119 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MHFCAHFK_01120 4.63e-135 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MHFCAHFK_01121 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHFCAHFK_01122 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
MHFCAHFK_01123 1.11e-84 - - - - - - - -
MHFCAHFK_01124 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
MHFCAHFK_01125 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHFCAHFK_01126 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MHFCAHFK_01127 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
MHFCAHFK_01128 1.15e-158 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHFCAHFK_01129 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
MHFCAHFK_01130 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHFCAHFK_01131 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
MHFCAHFK_01132 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHFCAHFK_01133 1.91e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHFCAHFK_01134 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHFCAHFK_01136 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
MHFCAHFK_01137 8.36e-25 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
MHFCAHFK_01138 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
MHFCAHFK_01139 1.14e-71 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MHFCAHFK_01140 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MHFCAHFK_01141 1.27e-224 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MHFCAHFK_01142 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHFCAHFK_01143 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
MHFCAHFK_01144 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MHFCAHFK_01145 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
MHFCAHFK_01146 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHFCAHFK_01147 6.31e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHFCAHFK_01148 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_01149 1.6e-96 - - - - - - - -
MHFCAHFK_01150 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHFCAHFK_01151 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MHFCAHFK_01152 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHFCAHFK_01153 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHFCAHFK_01154 7.94e-114 ykuL - - S - - - (CBS) domain
MHFCAHFK_01155 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHFCAHFK_01156 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHFCAHFK_01157 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHFCAHFK_01158 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
MHFCAHFK_01159 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHFCAHFK_01160 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHFCAHFK_01161 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHFCAHFK_01162 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
MHFCAHFK_01163 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHFCAHFK_01164 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
MHFCAHFK_01165 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHFCAHFK_01166 1.86e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHFCAHFK_01167 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHFCAHFK_01168 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHFCAHFK_01169 1.03e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHFCAHFK_01170 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHFCAHFK_01171 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHFCAHFK_01172 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHFCAHFK_01173 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHFCAHFK_01174 2.07e-118 - - - - - - - -
MHFCAHFK_01175 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MHFCAHFK_01176 1.35e-93 - - - - - - - -
MHFCAHFK_01177 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHFCAHFK_01178 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHFCAHFK_01179 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
MHFCAHFK_01180 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHFCAHFK_01181 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHFCAHFK_01182 2.21e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MHFCAHFK_01183 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHFCAHFK_01184 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MHFCAHFK_01185 0.0 ymfH - - S - - - Peptidase M16
MHFCAHFK_01186 3.55e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
MHFCAHFK_01187 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHFCAHFK_01188 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MHFCAHFK_01189 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01190 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01191 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHFCAHFK_01192 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHFCAHFK_01193 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MHFCAHFK_01194 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHFCAHFK_01195 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MHFCAHFK_01196 1.01e-114 radC - - L ko:K03630 - ko00000 DNA repair protein
MHFCAHFK_01197 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHFCAHFK_01198 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHFCAHFK_01199 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHFCAHFK_01200 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
MHFCAHFK_01201 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHFCAHFK_01202 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHFCAHFK_01203 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHFCAHFK_01204 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHFCAHFK_01205 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHFCAHFK_01206 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
MHFCAHFK_01207 2.82e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MHFCAHFK_01208 6.4e-142 - - - S - - - Protein of unknown function (DUF1648)
MHFCAHFK_01209 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_01210 4.74e-281 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MHFCAHFK_01211 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHFCAHFK_01212 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
MHFCAHFK_01213 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHFCAHFK_01214 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHFCAHFK_01215 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
MHFCAHFK_01216 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MHFCAHFK_01217 2.96e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHFCAHFK_01218 1.34e-52 - - - - - - - -
MHFCAHFK_01219 2.37e-107 uspA - - T - - - universal stress protein
MHFCAHFK_01220 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MHFCAHFK_01221 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
MHFCAHFK_01222 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MHFCAHFK_01223 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHFCAHFK_01224 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHFCAHFK_01225 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
MHFCAHFK_01226 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHFCAHFK_01227 1.23e-190 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHFCAHFK_01228 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01229 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHFCAHFK_01230 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MHFCAHFK_01231 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHFCAHFK_01232 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
MHFCAHFK_01233 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MHFCAHFK_01234 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MHFCAHFK_01235 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHFCAHFK_01236 1.69e-314 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHFCAHFK_01237 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHFCAHFK_01238 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHFCAHFK_01239 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHFCAHFK_01240 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHFCAHFK_01241 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHFCAHFK_01242 2.69e-70 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHFCAHFK_01243 6.31e-38 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHFCAHFK_01244 9.8e-133 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHFCAHFK_01245 2.04e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MHFCAHFK_01246 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHFCAHFK_01247 7.15e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHFCAHFK_01248 1.03e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHFCAHFK_01249 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHFCAHFK_01250 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHFCAHFK_01251 5e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHFCAHFK_01252 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MHFCAHFK_01253 2.5e-173 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MHFCAHFK_01254 1.17e-248 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHFCAHFK_01255 8.86e-244 ampC - - V - - - Beta-lactamase
MHFCAHFK_01256 2.1e-41 - - - - - - - -
MHFCAHFK_01257 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHFCAHFK_01258 1.33e-77 - - - - - - - -
MHFCAHFK_01259 3.1e-181 - - - - - - - -
MHFCAHFK_01260 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHFCAHFK_01261 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01262 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
MHFCAHFK_01263 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
MHFCAHFK_01265 1.26e-81 - - - K - - - IrrE N-terminal-like domain
MHFCAHFK_01267 1.15e-55 - - - S - - - Bacteriophage holin
MHFCAHFK_01268 4.55e-64 - - - - - - - -
MHFCAHFK_01269 1.28e-224 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MHFCAHFK_01273 2.29e-250 - - - S - - - Domain of unknown function (DUF2479)
MHFCAHFK_01276 2.16e-125 - - - S - - - Prophage endopeptidase tail
MHFCAHFK_01278 4.47e-178 - - - L - - - Phage tail tape measure protein TP901
MHFCAHFK_01281 6.76e-56 - - - N - - - domain, Protein
MHFCAHFK_01286 5.98e-06 - - - - - - - -
MHFCAHFK_01287 1.73e-135 - - - - - - - -
MHFCAHFK_01289 2.77e-50 - - - S - - - Phage minor capsid protein 2
MHFCAHFK_01290 1.51e-136 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHFCAHFK_01291 2.34e-93 - - - S - - - Phage terminase, large subunit, PBSX family
MHFCAHFK_01292 4.77e-118 - - - S - - - Phage terminase, large subunit, PBSX family
MHFCAHFK_01293 4.73e-75 - - - S - - - Terminase small subunit
MHFCAHFK_01294 6.73e-21 - - - - - - - -
MHFCAHFK_01296 3.06e-22 - - - S - - - KTSC domain
MHFCAHFK_01301 3.18e-106 - - - S - - - Phage transcriptional regulator, ArpU family
MHFCAHFK_01302 1.24e-24 - - - - - - - -
MHFCAHFK_01304 1.05e-25 - - - S - - - YopX protein
MHFCAHFK_01306 1.07e-16 - - - - - - - -
MHFCAHFK_01307 9.47e-86 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MHFCAHFK_01308 5.77e-84 - - - - - - - -
MHFCAHFK_01309 1.05e-76 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
MHFCAHFK_01311 2.13e-194 - - - S - - - IstB-like ATP binding protein
MHFCAHFK_01312 7.78e-45 - - - L - - - Domain of unknown function (DUF4373)
MHFCAHFK_01313 2.85e-59 - - - S - - - Single-strand binding protein family
MHFCAHFK_01314 1.19e-79 - - - S - - - ERF superfamily
MHFCAHFK_01315 3.44e-109 - - - - - - - -
MHFCAHFK_01318 2.51e-109 - - - - - - - -
MHFCAHFK_01319 1.28e-69 - - - - - - - -
MHFCAHFK_01322 1.58e-21 - - - K ko:K22299 - ko00000,ko03000 Helix-turn-helix domain
MHFCAHFK_01323 6.17e-08 - - - K ko:K22299 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHFCAHFK_01325 1.78e-48 - - - M - - - Host cell surface-exposed lipoprotein
MHFCAHFK_01330 5.19e-10 - - - S - - - STAS-like domain of unknown function (DUF4325)
MHFCAHFK_01332 4.46e-277 int3 - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_01334 1.98e-40 - - - - - - - -
MHFCAHFK_01337 1.32e-79 - - - - - - - -
MHFCAHFK_01338 1.18e-55 - - - S - - - Phage gp6-like head-tail connector protein
MHFCAHFK_01339 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MHFCAHFK_01340 8.75e-260 - - - S - - - Phage portal protein
MHFCAHFK_01341 0.000495 - - - - - - - -
MHFCAHFK_01342 0.0 terL - - S - - - overlaps another CDS with the same product name
MHFCAHFK_01343 4.45e-101 - - - L - - - overlaps another CDS with the same product name
MHFCAHFK_01344 2.13e-88 - - - L ko:K07451 - ko00000,ko01000,ko02048 Phage-associated protein
MHFCAHFK_01345 1.48e-63 - - - S - - - Head-tail joining protein
MHFCAHFK_01347 9.64e-96 - - - - - - - -
MHFCAHFK_01348 0.0 - - - S - - - Virulence-associated protein E
MHFCAHFK_01349 2.13e-187 - - - L - - - DNA replication protein
MHFCAHFK_01350 2.62e-40 - - - - - - - -
MHFCAHFK_01351 1.14e-12 - - - - - - - -
MHFCAHFK_01354 5.12e-289 - - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_01355 1.28e-51 - - - - - - - -
MHFCAHFK_01356 9.28e-58 - - - - - - - -
MHFCAHFK_01357 1.27e-109 - - - K - - - MarR family
MHFCAHFK_01358 0.0 - - - D - - - nuclear chromosome segregation
MHFCAHFK_01359 0.0 inlJ - - M - - - MucBP domain
MHFCAHFK_01360 6.58e-24 - - - - - - - -
MHFCAHFK_01361 3.26e-24 - - - - - - - -
MHFCAHFK_01362 1.56e-22 - - - - - - - -
MHFCAHFK_01363 1.07e-26 - - - - - - - -
MHFCAHFK_01364 9.35e-24 - - - - - - - -
MHFCAHFK_01365 2.16e-26 - - - - - - - -
MHFCAHFK_01366 4.63e-24 - - - - - - - -
MHFCAHFK_01367 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
MHFCAHFK_01368 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_01369 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01370 2.1e-33 - - - - - - - -
MHFCAHFK_01371 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHFCAHFK_01372 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MHFCAHFK_01373 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MHFCAHFK_01374 0.0 yclK - - T - - - Histidine kinase
MHFCAHFK_01375 1.39e-171 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MHFCAHFK_01376 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MHFCAHFK_01377 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MHFCAHFK_01378 2.55e-218 - - - EG - - - EamA-like transporter family
MHFCAHFK_01380 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
MHFCAHFK_01381 5.34e-64 - - - - - - - -
MHFCAHFK_01382 4.55e-185 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MHFCAHFK_01383 9.07e-68 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MHFCAHFK_01384 8.05e-178 - - - F - - - NUDIX domain
MHFCAHFK_01385 2.68e-32 - - - - - - - -
MHFCAHFK_01387 1.35e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_01388 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MHFCAHFK_01389 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MHFCAHFK_01390 2.29e-48 - - - - - - - -
MHFCAHFK_01391 1.11e-45 - - - - - - - -
MHFCAHFK_01392 4.86e-279 - - - T - - - diguanylate cyclase
MHFCAHFK_01393 0.0 - - - S - - - ABC transporter, ATP-binding protein
MHFCAHFK_01394 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
MHFCAHFK_01395 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHFCAHFK_01396 9.2e-62 - - - - - - - -
MHFCAHFK_01397 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHFCAHFK_01398 1.46e-239 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHFCAHFK_01399 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
MHFCAHFK_01400 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MHFCAHFK_01401 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MHFCAHFK_01402 8.88e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MHFCAHFK_01403 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_01404 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHFCAHFK_01405 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01406 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MHFCAHFK_01407 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MHFCAHFK_01408 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
MHFCAHFK_01409 1.74e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHFCAHFK_01410 1.34e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHFCAHFK_01411 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MHFCAHFK_01412 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHFCAHFK_01413 1.05e-171 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHFCAHFK_01414 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHFCAHFK_01415 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHFCAHFK_01416 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MHFCAHFK_01417 1.11e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHFCAHFK_01418 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHFCAHFK_01419 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHFCAHFK_01420 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
MHFCAHFK_01421 3.05e-282 ysaA - - V - - - RDD family
MHFCAHFK_01422 1.03e-212 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHFCAHFK_01423 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
MHFCAHFK_01424 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
MHFCAHFK_01425 8.33e-189 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_01426 4.54e-126 - - - J - - - glyoxalase III activity
MHFCAHFK_01427 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHFCAHFK_01428 1.15e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHFCAHFK_01429 1.45e-46 - - - - - - - -
MHFCAHFK_01430 1.26e-143 - - - S - - - Protein of unknown function (DUF1211)
MHFCAHFK_01431 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MHFCAHFK_01432 0.0 - - - M - - - domain protein
MHFCAHFK_01433 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHFCAHFK_01434 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHFCAHFK_01435 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MHFCAHFK_01436 4.92e-90 - - - S - - - Immunity protein 63
MHFCAHFK_01437 2.59e-84 - - - - - - - -
MHFCAHFK_01438 2.35e-52 - - - - - - - -
MHFCAHFK_01439 6.97e-45 - - - - - - - -
MHFCAHFK_01440 4.85e-216 - - - - - - - -
MHFCAHFK_01441 6.26e-75 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
MHFCAHFK_01442 0.0 - - - M - - - domain protein
MHFCAHFK_01443 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_01444 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MHFCAHFK_01445 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHFCAHFK_01446 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHFCAHFK_01447 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01448 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHFCAHFK_01449 1.17e-101 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
MHFCAHFK_01450 2.82e-206 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_01451 4.27e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MHFCAHFK_01452 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHFCAHFK_01453 2.16e-103 - - - - - - - -
MHFCAHFK_01454 8.37e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MHFCAHFK_01455 2.67e-293 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MHFCAHFK_01456 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MHFCAHFK_01457 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MHFCAHFK_01458 0.0 sufI - - Q - - - Multicopper oxidase
MHFCAHFK_01459 1.19e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MHFCAHFK_01460 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
MHFCAHFK_01461 8.95e-60 - - - - - - - -
MHFCAHFK_01462 3.66e-226 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHFCAHFK_01463 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MHFCAHFK_01464 0.0 - - - P - - - Major Facilitator Superfamily
MHFCAHFK_01465 1.18e-121 - - - K - - - Transcriptional regulator PadR-like family
MHFCAHFK_01466 2.76e-59 - - - - - - - -
MHFCAHFK_01467 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHFCAHFK_01468 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MHFCAHFK_01469 1.1e-280 - - - - - - - -
MHFCAHFK_01470 6.46e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHFCAHFK_01471 5.67e-187 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHFCAHFK_01472 5.18e-115 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_01473 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHFCAHFK_01474 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
MHFCAHFK_01475 1.45e-79 - - - S - - - CHY zinc finger
MHFCAHFK_01476 2.03e-225 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHFCAHFK_01477 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHFCAHFK_01478 6.4e-54 - - - - - - - -
MHFCAHFK_01479 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHFCAHFK_01480 3.48e-40 - - - - - - - -
MHFCAHFK_01481 4.09e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MHFCAHFK_01482 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
MHFCAHFK_01484 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MHFCAHFK_01485 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MHFCAHFK_01486 1.08e-243 - - - - - - - -
MHFCAHFK_01487 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_01488 4.16e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHFCAHFK_01489 2.06e-30 - - - - - - - -
MHFCAHFK_01490 1.24e-116 - - - K - - - acetyltransferase
MHFCAHFK_01491 1.88e-111 - - - K - - - GNAT family
MHFCAHFK_01492 8.08e-110 - - - S - - - ASCH
MHFCAHFK_01493 6.1e-124 - - - K - - - Cupin domain
MHFCAHFK_01494 1.2e-261 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHFCAHFK_01495 9e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01496 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01497 7.53e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_01498 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
MHFCAHFK_01499 1.04e-35 - - - - - - - -
MHFCAHFK_01501 9.97e-50 - - - - - - - -
MHFCAHFK_01502 3.21e-286 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHFCAHFK_01503 1.24e-99 - - - K - - - Transcriptional regulator
MHFCAHFK_01504 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
MHFCAHFK_01505 7.54e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHFCAHFK_01506 2.03e-75 - - - - - - - -
MHFCAHFK_01507 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MHFCAHFK_01508 6.88e-170 - - - - - - - -
MHFCAHFK_01509 9.03e-229 - - - - - - - -
MHFCAHFK_01510 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
MHFCAHFK_01511 1.31e-97 - - - M - - - LysM domain protein
MHFCAHFK_01512 3.95e-79 - - - M - - - Lysin motif
MHFCAHFK_01513 2.63e-154 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_01514 9.28e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_01515 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_01516 5.88e-285 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHFCAHFK_01517 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHFCAHFK_01518 1.96e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHFCAHFK_01519 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MHFCAHFK_01520 6.79e-135 - - - K - - - transcriptional regulator
MHFCAHFK_01521 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MHFCAHFK_01522 1.49e-63 - - - - - - - -
MHFCAHFK_01523 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MHFCAHFK_01524 2.92e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHFCAHFK_01525 2.87e-56 - - - - - - - -
MHFCAHFK_01526 3.35e-75 - - - - - - - -
MHFCAHFK_01527 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_01528 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
MHFCAHFK_01529 2.42e-65 - - - - - - - -
MHFCAHFK_01530 1.1e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
MHFCAHFK_01531 9.08e-317 hpk2 - - T - - - Histidine kinase
MHFCAHFK_01532 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_01533 0.0 ydiC - - EGP - - - Major Facilitator
MHFCAHFK_01534 1.55e-55 - - - - - - - -
MHFCAHFK_01535 2.92e-57 - - - - - - - -
MHFCAHFK_01536 1.15e-152 - - - - - - - -
MHFCAHFK_01537 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHFCAHFK_01538 1.05e-155 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_01539 8.9e-96 ywnA - - K - - - Transcriptional regulator
MHFCAHFK_01540 3.2e-91 - - - - - - - -
MHFCAHFK_01541 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHFCAHFK_01542 6.12e-184 - - - - - - - -
MHFCAHFK_01543 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHFCAHFK_01544 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_01545 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHFCAHFK_01546 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MHFCAHFK_01547 2.21e-56 - - - - - - - -
MHFCAHFK_01548 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
MHFCAHFK_01549 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MHFCAHFK_01550 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MHFCAHFK_01551 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHFCAHFK_01552 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHFCAHFK_01553 4.3e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MHFCAHFK_01554 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MHFCAHFK_01555 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MHFCAHFK_01556 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MHFCAHFK_01557 2.98e-90 - - - - - - - -
MHFCAHFK_01558 1.22e-125 - - - - - - - -
MHFCAHFK_01559 3.43e-66 - - - - - - - -
MHFCAHFK_01560 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHFCAHFK_01561 1.21e-111 - - - - - - - -
MHFCAHFK_01562 2.15e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHFCAHFK_01563 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_01564 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MHFCAHFK_01565 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_01566 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHFCAHFK_01567 7.02e-126 - - - K - - - Helix-turn-helix domain
MHFCAHFK_01568 7.88e-283 - - - C - - - FAD dependent oxidoreductase
MHFCAHFK_01569 7.38e-220 - - - P - - - Major Facilitator Superfamily
MHFCAHFK_01570 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHFCAHFK_01571 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
MHFCAHFK_01572 1.57e-89 - - - - - - - -
MHFCAHFK_01573 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHFCAHFK_01574 2.16e-201 dkgB - - S - - - reductase
MHFCAHFK_01575 5.84e-115 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MHFCAHFK_01576 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01577 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHFCAHFK_01578 1.75e-149 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHFCAHFK_01580 1.89e-63 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_01581 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHFCAHFK_01582 3.13e-99 - - - L - - - Transposase DDE domain
MHFCAHFK_01583 2.94e-256 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_01584 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHFCAHFK_01585 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHFCAHFK_01586 3.81e-18 - - - - - - - -
MHFCAHFK_01587 3.03e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHFCAHFK_01588 8.83e-208 fbpA - - K - - - Domain of unknown function (DUF814)
MHFCAHFK_01589 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
MHFCAHFK_01590 6.33e-46 - - - - - - - -
MHFCAHFK_01591 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MHFCAHFK_01592 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
MHFCAHFK_01593 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHFCAHFK_01594 2.92e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFCAHFK_01595 9.25e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHFCAHFK_01596 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_01597 6.79e-58 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_01598 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_01599 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MHFCAHFK_01601 0.0 - - - M - - - domain protein
MHFCAHFK_01602 5.99e-213 mleR - - K - - - LysR substrate binding domain
MHFCAHFK_01603 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHFCAHFK_01604 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MHFCAHFK_01605 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHFCAHFK_01606 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHFCAHFK_01607 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MHFCAHFK_01608 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHFCAHFK_01609 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_01610 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MHFCAHFK_01611 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MHFCAHFK_01612 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
MHFCAHFK_01613 2.4e-170 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
MHFCAHFK_01614 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHFCAHFK_01615 1.66e-208 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHFCAHFK_01616 1.61e-46 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHFCAHFK_01617 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
MHFCAHFK_01618 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
MHFCAHFK_01619 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_01620 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_01621 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHFCAHFK_01622 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MHFCAHFK_01623 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
MHFCAHFK_01624 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MHFCAHFK_01625 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_01626 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MHFCAHFK_01627 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MHFCAHFK_01628 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MHFCAHFK_01629 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MHFCAHFK_01630 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_01631 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
MHFCAHFK_01632 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
MHFCAHFK_01633 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_01634 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MHFCAHFK_01635 1.04e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_01636 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MHFCAHFK_01637 3.37e-115 - - - - - - - -
MHFCAHFK_01638 3.16e-191 - - - - - - - -
MHFCAHFK_01639 7.71e-183 - - - - - - - -
MHFCAHFK_01640 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
MHFCAHFK_01641 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHFCAHFK_01642 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MHFCAHFK_01643 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01644 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHFCAHFK_01645 6.49e-268 - - - C - - - Oxidoreductase
MHFCAHFK_01646 0.0 - - - - - - - -
MHFCAHFK_01647 4.03e-132 - - - - - - - -
MHFCAHFK_01648 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MHFCAHFK_01649 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
MHFCAHFK_01650 6.75e-212 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
MHFCAHFK_01651 2.52e-203 morA - - S - - - reductase
MHFCAHFK_01653 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MHFCAHFK_01654 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_01655 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHFCAHFK_01656 3.73e-104 - - - S - - - Protein of unknown function (DUF3021)
MHFCAHFK_01657 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHFCAHFK_01658 4.45e-99 - - - K - - - Transcriptional regulator
MHFCAHFK_01659 2.01e-141 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MHFCAHFK_01660 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MHFCAHFK_01661 4.67e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MHFCAHFK_01662 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHFCAHFK_01663 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MHFCAHFK_01664 2.33e-125 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
MHFCAHFK_01665 1.24e-159 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
MHFCAHFK_01666 3.09e-209 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MHFCAHFK_01667 1.45e-162 - - - S - - - Membrane
MHFCAHFK_01668 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
MHFCAHFK_01669 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_01670 5.03e-95 - - - K - - - Transcriptional regulator
MHFCAHFK_01671 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_01672 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MHFCAHFK_01674 2.71e-254 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MHFCAHFK_01675 1.11e-215 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MHFCAHFK_01676 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MHFCAHFK_01677 9.62e-19 - - - - - - - -
MHFCAHFK_01678 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHFCAHFK_01679 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHFCAHFK_01680 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
MHFCAHFK_01681 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
MHFCAHFK_01682 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
MHFCAHFK_01683 1.06e-16 - - - - - - - -
MHFCAHFK_01684 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
MHFCAHFK_01685 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
MHFCAHFK_01686 7.62e-290 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
MHFCAHFK_01687 5.02e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHFCAHFK_01688 3.44e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_01689 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHFCAHFK_01690 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MHFCAHFK_01691 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MHFCAHFK_01692 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MHFCAHFK_01693 5.62e-132 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MHFCAHFK_01694 7.06e-93 - - - S - - - Protein of unknown function (DUF1694)
MHFCAHFK_01695 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHFCAHFK_01696 4.34e-31 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MHFCAHFK_01697 3.01e-118 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MHFCAHFK_01698 1.62e-105 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_01699 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_01700 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHFCAHFK_01701 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MHFCAHFK_01702 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
MHFCAHFK_01703 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_01704 2.62e-100 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_01705 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
MHFCAHFK_01706 1.17e-305 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHFCAHFK_01707 1.18e-146 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHFCAHFK_01708 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHFCAHFK_01709 2.58e-186 yxeH - - S - - - hydrolase
MHFCAHFK_01710 8.95e-225 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHFCAHFK_01712 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MHFCAHFK_01713 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MHFCAHFK_01714 1.08e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MHFCAHFK_01715 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHFCAHFK_01716 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHFCAHFK_01717 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_01718 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_01719 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_01720 3.25e-252 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MHFCAHFK_01721 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHFCAHFK_01722 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_01723 1.73e-178 yleF - - K - - - Helix-turn-helix domain, rpiR family
MHFCAHFK_01724 1.48e-103 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHFCAHFK_01725 3.91e-95 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_01726 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_01727 4.72e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
MHFCAHFK_01728 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_01729 1.07e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHFCAHFK_01730 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_01731 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_01732 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHFCAHFK_01733 1.14e-200 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MHFCAHFK_01734 1.23e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHFCAHFK_01735 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_01736 5.44e-174 - - - K - - - UTRA domain
MHFCAHFK_01737 2.63e-200 estA - - S - - - Putative esterase
MHFCAHFK_01738 2.09e-83 - - - - - - - -
MHFCAHFK_01739 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_01740 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
MHFCAHFK_01741 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
MHFCAHFK_01742 2.73e-201 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_01743 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHFCAHFK_01744 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHFCAHFK_01745 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_01746 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
MHFCAHFK_01747 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHFCAHFK_01748 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHFCAHFK_01749 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHFCAHFK_01750 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHFCAHFK_01751 4.07e-85 - - - S - - - pyridoxamine 5-phosphate
MHFCAHFK_01752 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MHFCAHFK_01753 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_01754 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHFCAHFK_01755 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MHFCAHFK_01756 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHFCAHFK_01757 2.72e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MHFCAHFK_01758 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MHFCAHFK_01759 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHFCAHFK_01760 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHFCAHFK_01761 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHFCAHFK_01762 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_01763 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHFCAHFK_01764 1.31e-128 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MHFCAHFK_01765 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
MHFCAHFK_01766 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
MHFCAHFK_01767 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MHFCAHFK_01768 2.49e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MHFCAHFK_01769 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MHFCAHFK_01770 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_01771 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MHFCAHFK_01772 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MHFCAHFK_01773 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHFCAHFK_01774 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MHFCAHFK_01775 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_01776 1.15e-282 - - - S - - - associated with various cellular activities
MHFCAHFK_01777 9.34e-317 - - - S - - - Putative metallopeptidase domain
MHFCAHFK_01778 1.03e-65 - - - - - - - -
MHFCAHFK_01779 9.96e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
MHFCAHFK_01780 7.83e-60 - - - - - - - -
MHFCAHFK_01781 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_01782 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_01783 9.43e-225 - - - S - - - Cell surface protein
MHFCAHFK_01784 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHFCAHFK_01785 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MHFCAHFK_01786 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHFCAHFK_01787 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHFCAHFK_01788 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MHFCAHFK_01789 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
MHFCAHFK_01790 7.94e-124 dpsB - - P - - - Belongs to the Dps family
MHFCAHFK_01791 1.01e-26 - - - - - - - -
MHFCAHFK_01792 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
MHFCAHFK_01793 1.28e-44 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
MHFCAHFK_01794 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_01795 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHFCAHFK_01796 3.28e-231 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MHFCAHFK_01797 4.31e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
MHFCAHFK_01798 8.41e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHFCAHFK_01799 5.05e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MHFCAHFK_01800 2.27e-101 - - - K - - - transcriptional regulator
MHFCAHFK_01801 4.61e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
MHFCAHFK_01802 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MHFCAHFK_01803 5.13e-138 - - - - - - - -
MHFCAHFK_01805 5.77e-81 - - - - - - - -
MHFCAHFK_01806 8.78e-71 - - - - - - - -
MHFCAHFK_01807 1.44e-107 - - - M - - - PFAM NLP P60 protein
MHFCAHFK_01808 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MHFCAHFK_01809 4.45e-38 - - - - - - - -
MHFCAHFK_01810 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MHFCAHFK_01811 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_01812 5.33e-114 - - - K - - - Winged helix DNA-binding domain
MHFCAHFK_01813 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MHFCAHFK_01814 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
MHFCAHFK_01815 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
MHFCAHFK_01816 0.0 - - - - - - - -
MHFCAHFK_01817 3.42e-212 - - - S - - - Protein of unknown function (DUF1002)
MHFCAHFK_01818 1.58e-66 - - - - - - - -
MHFCAHFK_01819 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
MHFCAHFK_01820 6.94e-117 ymdB - - S - - - Macro domain protein
MHFCAHFK_01821 5.43e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHFCAHFK_01822 3.68e-57 - - - S - - - Protein of unknown function (DUF1093)
MHFCAHFK_01823 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
MHFCAHFK_01824 2.57e-171 - - - S - - - Putative threonine/serine exporter
MHFCAHFK_01825 1.36e-209 yvgN - - C - - - Aldo keto reductase
MHFCAHFK_01826 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MHFCAHFK_01827 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHFCAHFK_01828 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MHFCAHFK_01829 1.43e-94 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHFCAHFK_01830 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
MHFCAHFK_01831 5.99e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MHFCAHFK_01832 2.52e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHFCAHFK_01833 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MHFCAHFK_01834 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
MHFCAHFK_01835 2.55e-65 - - - - - - - -
MHFCAHFK_01836 7.21e-35 - - - - - - - -
MHFCAHFK_01837 1.77e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MHFCAHFK_01838 3.43e-96 - - - S - - - COG NOG18757 non supervised orthologous group
MHFCAHFK_01839 4.26e-54 - - - - - - - -
MHFCAHFK_01840 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MHFCAHFK_01841 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHFCAHFK_01842 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHFCAHFK_01843 2.55e-145 - - - S - - - VIT family
MHFCAHFK_01844 2.66e-155 - - - S - - - membrane
MHFCAHFK_01845 1.63e-203 - - - EG - - - EamA-like transporter family
MHFCAHFK_01846 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
MHFCAHFK_01847 4.17e-149 - - - GM - - - NmrA-like family
MHFCAHFK_01848 4.79e-21 - - - - - - - -
MHFCAHFK_01849 9.27e-74 - - - - - - - -
MHFCAHFK_01850 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHFCAHFK_01851 1.11e-111 - - - - - - - -
MHFCAHFK_01852 2.11e-82 - - - - - - - -
MHFCAHFK_01853 7.08e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MHFCAHFK_01854 1.7e-70 - - - - - - - -
MHFCAHFK_01855 1.41e-86 yeaO - - S - - - Protein of unknown function, DUF488
MHFCAHFK_01856 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
MHFCAHFK_01857 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
MHFCAHFK_01858 1.12e-208 - - - GM - - - NmrA-like family
MHFCAHFK_01859 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
MHFCAHFK_01860 2.48e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_01861 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHFCAHFK_01862 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MHFCAHFK_01863 2.63e-36 - - - S - - - Belongs to the LOG family
MHFCAHFK_01864 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHFCAHFK_01865 2.55e-58 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_01866 4.5e-94 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_01867 1.01e-248 - - - S - - - domain, Protein
MHFCAHFK_01868 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
MHFCAHFK_01869 1.22e-126 - - - C - - - Nitroreductase family
MHFCAHFK_01870 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MHFCAHFK_01871 3.45e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHFCAHFK_01872 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_01873 1.22e-200 ccpB - - K - - - lacI family
MHFCAHFK_01874 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
MHFCAHFK_01875 1.18e-225 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHFCAHFK_01876 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MHFCAHFK_01877 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
MHFCAHFK_01878 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHFCAHFK_01879 9.38e-139 pncA - - Q - - - Isochorismatase family
MHFCAHFK_01880 2.66e-172 - - - - - - - -
MHFCAHFK_01881 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_01882 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MHFCAHFK_01883 4.17e-60 - - - S - - - Enterocin A Immunity
MHFCAHFK_01884 2.29e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
MHFCAHFK_01885 0.0 pepF2 - - E - - - Oligopeptidase F
MHFCAHFK_01886 5.55e-59 pepF2 - - E - - - Oligopeptidase F
MHFCAHFK_01887 1.4e-95 - - - K - - - Transcriptional regulator
MHFCAHFK_01888 1.86e-210 - - - - - - - -
MHFCAHFK_01889 1.23e-75 - - - - - - - -
MHFCAHFK_01890 4.83e-64 - - - - - - - -
MHFCAHFK_01891 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_01892 1.17e-88 - - - - - - - -
MHFCAHFK_01893 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
MHFCAHFK_01894 9.89e-74 ytpP - - CO - - - Thioredoxin
MHFCAHFK_01895 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MHFCAHFK_01896 3.89e-62 - - - - - - - -
MHFCAHFK_01897 2.16e-63 - - - - - - - -
MHFCAHFK_01898 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
MHFCAHFK_01899 4.05e-98 - - - - - - - -
MHFCAHFK_01900 4.15e-78 - - - - - - - -
MHFCAHFK_01901 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHFCAHFK_01902 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
MHFCAHFK_01903 1.02e-102 uspA3 - - T - - - universal stress protein
MHFCAHFK_01904 8.36e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHFCAHFK_01905 1.18e-24 - - - - - - - -
MHFCAHFK_01906 1.09e-55 - - - S - - - zinc-ribbon domain
MHFCAHFK_01907 9.66e-97 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHFCAHFK_01908 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHFCAHFK_01909 3.96e-30 - - - S - - - Protein of unknown function (DUF2929)
MHFCAHFK_01910 3.07e-284 - - - M - - - Glycosyl transferases group 1
MHFCAHFK_01911 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHFCAHFK_01912 2.25e-206 - - - S - - - Putative esterase
MHFCAHFK_01913 3.53e-169 - - - K - - - Transcriptional regulator
MHFCAHFK_01914 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHFCAHFK_01915 1.18e-176 - - - - - - - -
MHFCAHFK_01916 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHFCAHFK_01917 9.4e-178 rrp8 - - K - - - LytTr DNA-binding domain
MHFCAHFK_01918 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
MHFCAHFK_01919 1.55e-79 - - - - - - - -
MHFCAHFK_01920 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHFCAHFK_01921 2.97e-76 - - - - - - - -
MHFCAHFK_01922 0.0 yhdP - - S - - - Transporter associated domain
MHFCAHFK_01923 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MHFCAHFK_01924 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MHFCAHFK_01925 5.57e-269 yttB - - EGP - - - Major Facilitator
MHFCAHFK_01926 8.13e-82 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_01927 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
MHFCAHFK_01928 4.71e-74 - - - S - - - SdpI/YhfL protein family
MHFCAHFK_01929 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHFCAHFK_01930 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
MHFCAHFK_01931 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHFCAHFK_01932 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHFCAHFK_01933 3.59e-26 - - - - - - - -
MHFCAHFK_01934 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
MHFCAHFK_01935 5.73e-208 mleR - - K - - - LysR family
MHFCAHFK_01936 1.29e-148 - - - GM - - - NAD(P)H-binding
MHFCAHFK_01937 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
MHFCAHFK_01938 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHFCAHFK_01939 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHFCAHFK_01940 4.54e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MHFCAHFK_01941 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHFCAHFK_01942 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHFCAHFK_01943 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHFCAHFK_01944 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHFCAHFK_01945 4.77e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHFCAHFK_01946 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHFCAHFK_01947 1.42e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHFCAHFK_01948 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHFCAHFK_01949 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MHFCAHFK_01950 3.62e-304 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MHFCAHFK_01951 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
MHFCAHFK_01952 4.71e-208 - - - GM - - - NmrA-like family
MHFCAHFK_01953 1.25e-199 - - - T - - - EAL domain
MHFCAHFK_01954 1.85e-121 - - - - - - - -
MHFCAHFK_01955 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MHFCAHFK_01956 1.1e-158 - - - E - - - Methionine synthase
MHFCAHFK_01957 6.66e-281 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHFCAHFK_01958 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHFCAHFK_01959 1.79e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHFCAHFK_01960 1.04e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHFCAHFK_01961 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHFCAHFK_01962 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFCAHFK_01963 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFCAHFK_01964 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFCAHFK_01965 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHFCAHFK_01966 5.8e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHFCAHFK_01967 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHFCAHFK_01968 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MHFCAHFK_01969 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
MHFCAHFK_01970 5.76e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MHFCAHFK_01971 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHFCAHFK_01972 9.88e-152 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MHFCAHFK_01973 9.78e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_01974 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHFCAHFK_01975 2.91e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01976 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHFCAHFK_01977 1.94e-55 - - - - - - - -
MHFCAHFK_01978 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
MHFCAHFK_01979 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_01980 5.66e-189 - - - - - - - -
MHFCAHFK_01981 2.7e-104 usp5 - - T - - - universal stress protein
MHFCAHFK_01982 1.08e-47 - - - - - - - -
MHFCAHFK_01983 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
MHFCAHFK_01984 1.76e-114 - - - - - - - -
MHFCAHFK_01985 1.4e-65 - - - - - - - -
MHFCAHFK_01986 4.79e-13 - - - - - - - -
MHFCAHFK_01987 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHFCAHFK_01988 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
MHFCAHFK_01989 1.52e-151 - - - - - - - -
MHFCAHFK_01990 1.42e-68 - - - - - - - -
MHFCAHFK_01992 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHFCAHFK_01993 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MHFCAHFK_01994 1.1e-184 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_01995 2.38e-37 - - - S - - - Pentapeptide repeats (8 copies)
MHFCAHFK_01996 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHFCAHFK_01997 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MHFCAHFK_01998 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
MHFCAHFK_01999 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_02000 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MHFCAHFK_02001 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHFCAHFK_02002 4.43e-294 - - - S - - - Sterol carrier protein domain
MHFCAHFK_02003 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
MHFCAHFK_02004 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHFCAHFK_02005 2.13e-152 - - - K - - - Transcriptional regulator
MHFCAHFK_02006 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_02007 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHFCAHFK_02008 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MHFCAHFK_02009 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_02010 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_02011 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MHFCAHFK_02012 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_02013 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MHFCAHFK_02014 1.4e-181 epsV - - S - - - glycosyl transferase family 2
MHFCAHFK_02015 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
MHFCAHFK_02016 7.63e-107 - - - - - - - -
MHFCAHFK_02017 5.06e-196 - - - S - - - hydrolase
MHFCAHFK_02018 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHFCAHFK_02019 2.8e-204 - - - EG - - - EamA-like transporter family
MHFCAHFK_02020 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHFCAHFK_02021 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHFCAHFK_02022 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
MHFCAHFK_02023 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MHFCAHFK_02024 0.0 - - - M - - - Domain of unknown function (DUF5011)
MHFCAHFK_02025 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MHFCAHFK_02026 4.3e-44 - - - - - - - -
MHFCAHFK_02027 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
MHFCAHFK_02028 0.0 ycaM - - E - - - amino acid
MHFCAHFK_02029 2.45e-101 - - - K - - - Winged helix DNA-binding domain
MHFCAHFK_02030 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MHFCAHFK_02031 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MHFCAHFK_02032 1.3e-209 - - - K - - - Transcriptional regulator
MHFCAHFK_02034 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHFCAHFK_02035 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MHFCAHFK_02036 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MHFCAHFK_02037 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MHFCAHFK_02038 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHFCAHFK_02039 3.14e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MHFCAHFK_02040 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
MHFCAHFK_02041 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHFCAHFK_02042 3.87e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHFCAHFK_02043 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MHFCAHFK_02044 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MHFCAHFK_02045 2.51e-103 - - - T - - - Universal stress protein family
MHFCAHFK_02046 7.43e-130 padR - - K - - - Virulence activator alpha C-term
MHFCAHFK_02047 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MHFCAHFK_02048 3.79e-181 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MHFCAHFK_02049 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
MHFCAHFK_02050 4.02e-203 degV1 - - S - - - DegV family
MHFCAHFK_02051 2.32e-78 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MHFCAHFK_02052 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MHFCAHFK_02054 1.12e-140 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHFCAHFK_02055 0.0 - - - - - - - -
MHFCAHFK_02057 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
MHFCAHFK_02058 1.31e-143 - - - S - - - Cell surface protein
MHFCAHFK_02059 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHFCAHFK_02060 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHFCAHFK_02061 5.56e-172 jag - - S ko:K06346 - ko00000 R3H domain protein
MHFCAHFK_02062 2.64e-305 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MHFCAHFK_02063 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_02064 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHFCAHFK_02065 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHFCAHFK_02066 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHFCAHFK_02067 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHFCAHFK_02068 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MHFCAHFK_02069 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHFCAHFK_02070 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHFCAHFK_02071 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHFCAHFK_02072 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHFCAHFK_02073 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHFCAHFK_02074 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHFCAHFK_02075 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHFCAHFK_02076 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHFCAHFK_02077 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHFCAHFK_02078 4.96e-289 yttB - - EGP - - - Major Facilitator
MHFCAHFK_02079 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHFCAHFK_02080 9.32e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHFCAHFK_02082 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_02084 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHFCAHFK_02085 2.98e-269 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHFCAHFK_02086 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MHFCAHFK_02087 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHFCAHFK_02088 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHFCAHFK_02089 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHFCAHFK_02091 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
MHFCAHFK_02092 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MHFCAHFK_02093 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
MHFCAHFK_02094 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MHFCAHFK_02095 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
MHFCAHFK_02096 2.54e-50 - - - - - - - -
MHFCAHFK_02097 2.01e-290 sip - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_02100 4.64e-12 - - - - - - - -
MHFCAHFK_02102 6.22e-43 - - - - - - - -
MHFCAHFK_02103 5.62e-183 - - - L - - - DNA replication protein
MHFCAHFK_02104 0.0 - - - S - - - Virulence-associated protein E
MHFCAHFK_02105 6.15e-95 - - - - - - - -
MHFCAHFK_02107 3.93e-68 - - - S - - - Head-tail joining protein
MHFCAHFK_02108 5.02e-87 - - - L - - - HNH endonuclease
MHFCAHFK_02109 2.59e-107 - - - L - - - overlaps another CDS with the same product name
MHFCAHFK_02110 0.0 terL - - S - - - overlaps another CDS with the same product name
MHFCAHFK_02112 3.81e-254 - - - S - - - Phage portal protein
MHFCAHFK_02113 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
MHFCAHFK_02114 1.01e-56 - - - S - - - Phage gp6-like head-tail connector protein
MHFCAHFK_02115 1.14e-52 - - - - - - - -
MHFCAHFK_02116 4.33e-50 - - - V - - - Abi-like protein
MHFCAHFK_02118 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHFCAHFK_02119 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHFCAHFK_02120 5.04e-313 yycH - - S - - - YycH protein
MHFCAHFK_02121 3.54e-195 yycI - - S - - - YycH protein
MHFCAHFK_02122 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MHFCAHFK_02123 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MHFCAHFK_02124 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHFCAHFK_02125 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_02126 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
MHFCAHFK_02127 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
MHFCAHFK_02128 2.24e-155 pnb - - C - - - nitroreductase
MHFCAHFK_02129 2.02e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MHFCAHFK_02130 5.25e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
MHFCAHFK_02131 0.0 - - - C - - - FMN_bind
MHFCAHFK_02132 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHFCAHFK_02133 1.46e-204 - - - K - - - LysR family
MHFCAHFK_02134 2.49e-95 - - - C - - - FMN binding
MHFCAHFK_02135 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHFCAHFK_02136 4.06e-211 - - - S - - - KR domain
MHFCAHFK_02137 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MHFCAHFK_02138 5.07e-157 ydgI - - C - - - Nitroreductase family
MHFCAHFK_02139 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MHFCAHFK_02140 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MHFCAHFK_02141 4.47e-73 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHFCAHFK_02142 2.95e-125 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHFCAHFK_02143 0.0 - - - S - - - Putative threonine/serine exporter
MHFCAHFK_02144 3.97e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHFCAHFK_02145 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
MHFCAHFK_02146 1.65e-106 - - - S - - - ASCH
MHFCAHFK_02147 3.06e-165 - - - F - - - glutamine amidotransferase
MHFCAHFK_02148 5.06e-141 - - - K - - - WYL domain
MHFCAHFK_02149 2.39e-66 - - - K - - - WYL domain
MHFCAHFK_02150 1.34e-151 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHFCAHFK_02151 1.76e-18 fusA1 - - J - - - elongation factor G
MHFCAHFK_02152 0.0 fusA1 - - J - - - elongation factor G
MHFCAHFK_02153 4.67e-38 - - - S - - - Protein of unknown function
MHFCAHFK_02154 1.07e-62 - - - S - - - Protein of unknown function
MHFCAHFK_02155 4.28e-195 - - - EG - - - EamA-like transporter family
MHFCAHFK_02156 7.65e-121 yfbM - - K - - - FR47-like protein
MHFCAHFK_02157 1.4e-162 - - - S - - - DJ-1/PfpI family
MHFCAHFK_02158 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHFCAHFK_02159 1.02e-63 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_02160 1.71e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MHFCAHFK_02161 6.08e-213 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHFCAHFK_02162 9.06e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MHFCAHFK_02163 2.38e-99 - - - - - - - -
MHFCAHFK_02164 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MHFCAHFK_02165 4.85e-180 - - - - - - - -
MHFCAHFK_02166 4.07e-05 - - - - - - - -
MHFCAHFK_02167 2.17e-141 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MHFCAHFK_02168 1.67e-54 - - - - - - - -
MHFCAHFK_02169 4.16e-143 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHFCAHFK_02170 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MHFCAHFK_02171 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
MHFCAHFK_02172 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
MHFCAHFK_02173 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
MHFCAHFK_02174 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
MHFCAHFK_02175 2.9e-178 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MHFCAHFK_02176 1.75e-98 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
MHFCAHFK_02177 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHFCAHFK_02178 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
MHFCAHFK_02179 3.94e-224 - - - C - - - Zinc-binding dehydrogenase
MHFCAHFK_02180 3.77e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHFCAHFK_02181 3.03e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHFCAHFK_02182 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHFCAHFK_02183 1.97e-259 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MHFCAHFK_02184 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MHFCAHFK_02185 0.0 - - - L - - - HIRAN domain
MHFCAHFK_02186 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MHFCAHFK_02187 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MHFCAHFK_02188 1e-156 - - - - - - - -
MHFCAHFK_02189 2.94e-191 - - - I - - - Alpha/beta hydrolase family
MHFCAHFK_02190 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHFCAHFK_02191 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHFCAHFK_02192 6.22e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHFCAHFK_02193 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHFCAHFK_02194 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHFCAHFK_02195 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHFCAHFK_02196 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHFCAHFK_02197 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
MHFCAHFK_02198 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MHFCAHFK_02200 7.72e-57 yabO - - J - - - S4 domain protein
MHFCAHFK_02201 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHFCAHFK_02202 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHFCAHFK_02203 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHFCAHFK_02204 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHFCAHFK_02205 0.0 - - - S - - - Putative peptidoglycan binding domain
MHFCAHFK_02206 4.87e-148 - - - S - - - (CBS) domain
MHFCAHFK_02207 1.3e-110 queT - - S - - - QueT transporter
MHFCAHFK_02208 1.85e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHFCAHFK_02209 4.47e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
MHFCAHFK_02210 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MHFCAHFK_02211 9.73e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHFCAHFK_02212 1.72e-242 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHFCAHFK_02213 1.51e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHFCAHFK_02214 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHFCAHFK_02215 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHFCAHFK_02216 7.11e-201 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_02217 7.93e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_02218 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHFCAHFK_02219 6.65e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHFCAHFK_02220 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHFCAHFK_02221 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHFCAHFK_02222 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHFCAHFK_02223 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHFCAHFK_02224 2.16e-157 - - - - - - - -
MHFCAHFK_02225 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MHFCAHFK_02226 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
MHFCAHFK_02227 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MHFCAHFK_02228 1.49e-273 - - - J - - - translation release factor activity
MHFCAHFK_02229 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHFCAHFK_02230 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHFCAHFK_02231 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHFCAHFK_02232 2.41e-37 - - - - - - - -
MHFCAHFK_02233 1.89e-169 - - - S - - - YheO-like PAS domain
MHFCAHFK_02234 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHFCAHFK_02235 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MHFCAHFK_02236 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
MHFCAHFK_02237 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHFCAHFK_02238 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHFCAHFK_02239 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHFCAHFK_02240 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
MHFCAHFK_02241 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MHFCAHFK_02242 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MHFCAHFK_02243 4.15e-191 yxeH - - S - - - hydrolase
MHFCAHFK_02244 7.12e-178 - - - - - - - -
MHFCAHFK_02245 1.15e-235 - - - S - - - DUF218 domain
MHFCAHFK_02246 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHFCAHFK_02247 1.1e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MHFCAHFK_02248 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHFCAHFK_02249 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHFCAHFK_02250 5.3e-49 - - - - - - - -
MHFCAHFK_02251 2.4e-56 - - - S - - - ankyrin repeats
MHFCAHFK_02252 3.71e-15 - - - T ko:K21493 - ko00000,ko01000,ko02048 Pre-toxin TG
MHFCAHFK_02253 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHFCAHFK_02254 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHFCAHFK_02255 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
MHFCAHFK_02256 1.86e-208 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHFCAHFK_02257 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
MHFCAHFK_02258 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHFCAHFK_02259 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHFCAHFK_02260 6.64e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MHFCAHFK_02261 1.17e-269 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
MHFCAHFK_02262 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHFCAHFK_02263 4.64e-92 - - - F - - - DNA mismatch repair protein MutT
MHFCAHFK_02264 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
MHFCAHFK_02265 8.73e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MHFCAHFK_02266 4.65e-229 - - - - - - - -
MHFCAHFK_02267 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MHFCAHFK_02268 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHFCAHFK_02269 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
MHFCAHFK_02270 4.99e-262 - - - - - - - -
MHFCAHFK_02271 2.94e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHFCAHFK_02272 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
MHFCAHFK_02273 6.97e-209 - - - GK - - - ROK family
MHFCAHFK_02274 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_02275 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_02276 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
MHFCAHFK_02277 9.68e-34 - - - - - - - -
MHFCAHFK_02278 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_02279 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
MHFCAHFK_02280 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHFCAHFK_02281 1.38e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MHFCAHFK_02282 0.0 - - - L - - - DNA helicase
MHFCAHFK_02283 1.85e-40 - - - - - - - -
MHFCAHFK_02284 3.34e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02285 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02286 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02287 3.26e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02288 1.49e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MHFCAHFK_02289 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHFCAHFK_02290 8.82e-32 - - - - - - - -
MHFCAHFK_02291 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02292 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHFCAHFK_02293 2.48e-172 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHFCAHFK_02294 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHFCAHFK_02295 1.9e-25 plnA - - - - - - -
MHFCAHFK_02296 1.22e-36 - - - - - - - -
MHFCAHFK_02297 2.08e-160 plnP - - S - - - CAAX protease self-immunity
MHFCAHFK_02298 5.58e-291 - - - M - - - Glycosyl transferase family 2
MHFCAHFK_02300 4.08e-39 - - - - - - - -
MHFCAHFK_02301 8.53e-34 plnJ - - - - - - -
MHFCAHFK_02302 3.29e-32 plnK - - - - - - -
MHFCAHFK_02303 9.76e-153 - - - - - - - -
MHFCAHFK_02304 6.24e-25 plnR - - - - - - -
MHFCAHFK_02305 1.15e-43 - - - - - - - -
MHFCAHFK_02307 3.58e-264 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHFCAHFK_02308 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHFCAHFK_02310 8.38e-192 - - - S - - - hydrolase
MHFCAHFK_02311 2.35e-212 - - - K - - - Transcriptional regulator
MHFCAHFK_02312 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_02313 7.81e-263 - - - EGP - - - Transporter, major facilitator family protein
MHFCAHFK_02314 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHFCAHFK_02315 5.32e-51 - - - - - - - -
MHFCAHFK_02316 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHFCAHFK_02317 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHFCAHFK_02318 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHFCAHFK_02319 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHFCAHFK_02320 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MHFCAHFK_02321 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
MHFCAHFK_02322 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MHFCAHFK_02323 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHFCAHFK_02324 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHFCAHFK_02325 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MHFCAHFK_02326 4.48e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHFCAHFK_02327 1.19e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHFCAHFK_02328 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHFCAHFK_02329 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHFCAHFK_02330 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MHFCAHFK_02331 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHFCAHFK_02332 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHFCAHFK_02333 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHFCAHFK_02334 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MHFCAHFK_02335 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MHFCAHFK_02336 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MHFCAHFK_02337 7.67e-198 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHFCAHFK_02338 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MHFCAHFK_02339 0.0 ydaO - - E - - - amino acid
MHFCAHFK_02340 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHFCAHFK_02341 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHFCAHFK_02342 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_02343 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHFCAHFK_02344 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MHFCAHFK_02345 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHFCAHFK_02346 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHFCAHFK_02347 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MHFCAHFK_02348 3.95e-166 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MHFCAHFK_02349 2.84e-241 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MHFCAHFK_02350 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHFCAHFK_02351 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
MHFCAHFK_02352 9.12e-112 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_02353 2.23e-54 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_02354 1.14e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
MHFCAHFK_02355 5.35e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MHFCAHFK_02356 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHFCAHFK_02357 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MHFCAHFK_02358 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHFCAHFK_02359 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
MHFCAHFK_02360 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHFCAHFK_02361 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MHFCAHFK_02362 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHFCAHFK_02363 1.16e-128 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MHFCAHFK_02364 4.67e-280 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHFCAHFK_02365 2.27e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_02366 4.97e-67 - 2.7.1.194 - G ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_02368 2.73e-254 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_02369 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
MHFCAHFK_02370 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHFCAHFK_02371 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHFCAHFK_02372 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHFCAHFK_02373 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHFCAHFK_02374 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHFCAHFK_02375 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MHFCAHFK_02376 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHFCAHFK_02377 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHFCAHFK_02378 1.37e-139 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MHFCAHFK_02379 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHFCAHFK_02380 1.78e-88 - - - L - - - nuclease
MHFCAHFK_02381 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHFCAHFK_02382 4.9e-283 - - - - - - - -
MHFCAHFK_02384 7.98e-68 hol - - S - - - COG5546 Small integral membrane protein
MHFCAHFK_02385 5.53e-65 - - - - - - - -
MHFCAHFK_02386 1.2e-259 - - - M - - - hydrolase, family 25
MHFCAHFK_02387 2.56e-34 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
MHFCAHFK_02390 1.92e-141 - - - S - - - Domain of unknown function (DUF2479)
MHFCAHFK_02391 3.46e-241 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MHFCAHFK_02392 0.0 - - - M - - - Prophage endopeptidase tail
MHFCAHFK_02393 1.19e-182 - - - S - - - phage tail
MHFCAHFK_02394 0.0 - - - D - - - domain protein
MHFCAHFK_02396 1.41e-115 - - - S - - - Phage tail assembly chaperone protein, TAC
MHFCAHFK_02397 2.55e-137 - - - - - - - -
MHFCAHFK_02398 1.9e-86 - - - - - - - -
MHFCAHFK_02399 2.57e-127 - - - - - - - -
MHFCAHFK_02400 7.48e-74 - - - - - - - -
MHFCAHFK_02401 1.73e-81 - - - S - - - Phage gp6-like head-tail connector protein
MHFCAHFK_02402 1.1e-257 gpG - - - - - - -
MHFCAHFK_02403 1.38e-112 - - - S - - - Domain of unknown function (DUF4355)
MHFCAHFK_02404 1.75e-226 - - - S - - - Phage Mu protein F like protein
MHFCAHFK_02405 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHFCAHFK_02406 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
MHFCAHFK_02407 9.87e-132 - - - L ko:K07474 - ko00000 Terminase small subunit
MHFCAHFK_02409 7.73e-23 - - - - - - - -
MHFCAHFK_02412 2.15e-106 - - - S - - - Phage transcriptional regulator, ArpU family
MHFCAHFK_02413 7.97e-30 - - - - - - - -
MHFCAHFK_02414 2.44e-17 - - - - - - - -
MHFCAHFK_02415 3.06e-79 - - - S - - - YopX protein
MHFCAHFK_02421 2.57e-90 rusA - - L - - - Endodeoxyribonuclease RusA
MHFCAHFK_02422 3.29e-105 - - - - - - - -
MHFCAHFK_02423 2.57e-82 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
MHFCAHFK_02424 1.81e-64 - - - - - - - -
MHFCAHFK_02425 9.06e-34 - - - L - - - Domain of unknown function (DUF4373)
MHFCAHFK_02426 1.46e-59 - - - S - - - ERF superfamily
MHFCAHFK_02428 4.63e-91 - - - - - - - -
MHFCAHFK_02431 3.66e-127 - - - - - - - -
MHFCAHFK_02434 1.13e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHFCAHFK_02435 8.29e-51 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MHFCAHFK_02437 6.7e-36 - - - K - - - Helix-turn-helix
MHFCAHFK_02438 1.32e-80 - - - K - - - Helix-turn-helix domain
MHFCAHFK_02439 8.11e-95 - - - E - - - IrrE N-terminal-like domain
MHFCAHFK_02440 9.61e-75 - - - - - - - -
MHFCAHFK_02441 2.42e-209 - - - M - - - Host cell surface-exposed lipoprotein
MHFCAHFK_02445 1.12e-252 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHFCAHFK_02447 2.33e-68 - - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_02448 4.92e-215 - - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_02450 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHFCAHFK_02451 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHFCAHFK_02452 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHFCAHFK_02453 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHFCAHFK_02454 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHFCAHFK_02455 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHFCAHFK_02456 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHFCAHFK_02457 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHFCAHFK_02458 3.22e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
MHFCAHFK_02459 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MHFCAHFK_02460 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHFCAHFK_02461 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHFCAHFK_02462 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHFCAHFK_02463 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHFCAHFK_02464 4.91e-265 yacL - - S - - - domain protein
MHFCAHFK_02465 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHFCAHFK_02466 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MHFCAHFK_02467 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MHFCAHFK_02468 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHFCAHFK_02469 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MHFCAHFK_02470 4.35e-146 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MHFCAHFK_02471 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MHFCAHFK_02472 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
MHFCAHFK_02473 1.07e-205 - - - S - - - Alpha beta hydrolase
MHFCAHFK_02474 1.02e-145 - - - GM - - - NmrA-like family
MHFCAHFK_02475 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MHFCAHFK_02476 5.72e-207 - - - K - - - Transcriptional regulator
MHFCAHFK_02477 2.66e-221 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHFCAHFK_02479 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHFCAHFK_02480 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHFCAHFK_02481 2.08e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHFCAHFK_02482 1.81e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHFCAHFK_02483 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_02485 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHFCAHFK_02486 3.89e-94 - - - K - - - MarR family
MHFCAHFK_02487 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
MHFCAHFK_02488 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
MHFCAHFK_02489 4.5e-93 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_02490 9.32e-104 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_02491 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHFCAHFK_02492 2.48e-252 - - - - - - - -
MHFCAHFK_02493 5.01e-254 - - - - - - - -
MHFCAHFK_02494 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_02495 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHFCAHFK_02496 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHFCAHFK_02497 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHFCAHFK_02498 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHFCAHFK_02499 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHFCAHFK_02500 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHFCAHFK_02501 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHFCAHFK_02502 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHFCAHFK_02503 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHFCAHFK_02504 9.71e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MHFCAHFK_02505 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MHFCAHFK_02506 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHFCAHFK_02507 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHFCAHFK_02508 2.35e-81 - - - C - - - Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_02509 3.83e-70 - - - C - - - Enoyl-(Acyl carrier protein) reductase
MHFCAHFK_02510 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHFCAHFK_02511 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHFCAHFK_02512 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHFCAHFK_02513 2.15e-131 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHFCAHFK_02514 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHFCAHFK_02515 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHFCAHFK_02516 1.15e-199 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MHFCAHFK_02517 2.65e-213 - - - G - - - Fructosamine kinase
MHFCAHFK_02518 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
MHFCAHFK_02519 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHFCAHFK_02520 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHFCAHFK_02521 1.49e-75 - - - - - - - -
MHFCAHFK_02522 1.27e-171 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHFCAHFK_02523 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MHFCAHFK_02524 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MHFCAHFK_02525 4.78e-65 - - - - - - - -
MHFCAHFK_02526 1.73e-67 - - - - - - - -
MHFCAHFK_02527 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHFCAHFK_02528 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHFCAHFK_02529 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHFCAHFK_02530 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MHFCAHFK_02531 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHFCAHFK_02532 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MHFCAHFK_02533 8.49e-266 pbpX2 - - V - - - Beta-lactamase
MHFCAHFK_02534 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHFCAHFK_02535 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHFCAHFK_02536 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHFCAHFK_02537 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHFCAHFK_02538 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHFCAHFK_02539 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHFCAHFK_02540 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHFCAHFK_02541 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHFCAHFK_02542 5.99e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MHFCAHFK_02543 6.72e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHFCAHFK_02544 6.65e-121 - - - - - - - -
MHFCAHFK_02545 3.67e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHFCAHFK_02546 0.0 - - - G - - - Major Facilitator
MHFCAHFK_02547 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHFCAHFK_02548 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHFCAHFK_02549 1.66e-37 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHFCAHFK_02550 3.28e-63 ylxQ - - J - - - ribosomal protein
MHFCAHFK_02551 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MHFCAHFK_02552 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHFCAHFK_02553 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHFCAHFK_02554 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHFCAHFK_02555 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHFCAHFK_02556 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHFCAHFK_02557 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHFCAHFK_02558 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHFCAHFK_02559 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHFCAHFK_02560 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHFCAHFK_02561 1.55e-193 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHFCAHFK_02562 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHFCAHFK_02563 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MHFCAHFK_02564 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFCAHFK_02565 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MHFCAHFK_02566 3.65e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MHFCAHFK_02567 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MHFCAHFK_02568 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MHFCAHFK_02569 7.68e-48 ynzC - - S - - - UPF0291 protein
MHFCAHFK_02570 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHFCAHFK_02571 1.83e-121 - - - - - - - -
MHFCAHFK_02572 6.62e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MHFCAHFK_02573 7.42e-64 - - - - - - - -
MHFCAHFK_02574 3.26e-88 - - - - - - - -
MHFCAHFK_02575 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
MHFCAHFK_02578 5.32e-12 - - - S - - - Short C-terminal domain
MHFCAHFK_02579 1.79e-21 - - - S - - - Short C-terminal domain
MHFCAHFK_02580 5.48e-05 - - - S - - - Short C-terminal domain
MHFCAHFK_02581 6.9e-52 - - - L - - - HTH-like domain
MHFCAHFK_02582 1.01e-42 - - - L ko:K07483 - ko00000 transposase activity
MHFCAHFK_02583 1.54e-50 int2 - - L - - - Belongs to the 'phage' integrase family
MHFCAHFK_02586 1.75e-43 - - - - - - - -
MHFCAHFK_02587 1.14e-180 - - - Q - - - Methyltransferase
MHFCAHFK_02588 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
MHFCAHFK_02589 2.87e-270 - - - EGP - - - Major facilitator Superfamily
MHFCAHFK_02590 7.9e-136 - - - K - - - Helix-turn-helix domain
MHFCAHFK_02591 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHFCAHFK_02592 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHFCAHFK_02593 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
MHFCAHFK_02594 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFCAHFK_02595 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHFCAHFK_02596 6.62e-62 - - - - - - - -
MHFCAHFK_02597 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHFCAHFK_02598 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHFCAHFK_02599 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHFCAHFK_02600 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MHFCAHFK_02601 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MHFCAHFK_02602 0.0 cps4J - - S - - - MatE
MHFCAHFK_02603 9.73e-228 cps4I - - M - - - Glycosyltransferase like family 2
MHFCAHFK_02604 3.68e-295 - - - - - - - -
MHFCAHFK_02605 1.99e-237 cps4G - - M - - - Glycosyltransferase Family 4
MHFCAHFK_02606 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
MHFCAHFK_02607 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
MHFCAHFK_02608 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MHFCAHFK_02609 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHFCAHFK_02610 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
MHFCAHFK_02611 8.45e-162 epsB - - M - - - biosynthesis protein
MHFCAHFK_02612 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHFCAHFK_02613 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_02614 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHFCAHFK_02615 5.12e-31 - - - - - - - -
MHFCAHFK_02616 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
MHFCAHFK_02617 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
MHFCAHFK_02618 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHFCAHFK_02619 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHFCAHFK_02620 1.46e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHFCAHFK_02621 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHFCAHFK_02622 5.89e-204 - - - S - - - Tetratricopeptide repeat
MHFCAHFK_02623 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHFCAHFK_02624 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHFCAHFK_02625 1.82e-260 - - - EGP - - - Major Facilitator Superfamily
MHFCAHFK_02626 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHFCAHFK_02627 1.04e-13 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHFCAHFK_02628 2.07e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHFCAHFK_02629 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHFCAHFK_02630 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHFCAHFK_02631 3.85e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MHFCAHFK_02632 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHFCAHFK_02633 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHFCAHFK_02634 6.06e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MHFCAHFK_02635 4.82e-33 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MHFCAHFK_02636 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHFCAHFK_02637 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHFCAHFK_02638 0.0 - - - - - - - -
MHFCAHFK_02639 4.74e-152 icaA - - M - - - Glycosyl transferase family group 2
MHFCAHFK_02640 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHFCAHFK_02641 1.43e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MHFCAHFK_02642 6.24e-61 yktA - - S - - - Belongs to the UPF0223 family
MHFCAHFK_02643 1.24e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MHFCAHFK_02644 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MHFCAHFK_02645 3.35e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHFCAHFK_02646 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MHFCAHFK_02647 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHFCAHFK_02648 2.29e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHFCAHFK_02649 6.45e-111 - - - - - - - -
MHFCAHFK_02650 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
MHFCAHFK_02651 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHFCAHFK_02652 2.43e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHFCAHFK_02653 6.21e-39 - - - - - - - -
MHFCAHFK_02654 7e-259 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHFCAHFK_02655 9.81e-166 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MHFCAHFK_02656 6.52e-36 - - - - - - - -
MHFCAHFK_02657 1.18e-118 traA - - L - - - MobA MobL family protein
MHFCAHFK_02658 2.44e-315 traA - - L - - - MobA MobL family protein
MHFCAHFK_02659 1.75e-49 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_02660 2.56e-279 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_02661 4.22e-41 - - - - - - - -
MHFCAHFK_02662 5.11e-247 - - - L - - - Psort location Cytoplasmic, score
MHFCAHFK_02663 1.1e-110 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHFCAHFK_02664 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHFCAHFK_02665 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MHFCAHFK_02666 1.33e-77 - - - - - - - -
MHFCAHFK_02667 1.59e-61 - - - - - - - -
MHFCAHFK_02668 3.77e-287 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MHFCAHFK_02669 1.77e-18 - - - S - - - Putative Holin-like Toxin (Hol-Tox)
MHFCAHFK_02670 7.71e-235 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
MHFCAHFK_02671 1.48e-191 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
MHFCAHFK_02672 7.65e-195 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
MHFCAHFK_02673 9.15e-91 - - - KT - - - Purine catabolism regulatory protein-like family
MHFCAHFK_02674 2.31e-48 - - - K - - - LysR substrate binding domain
MHFCAHFK_02675 2.17e-131 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MHFCAHFK_02676 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
MHFCAHFK_02677 1.31e-288 - - - L - - - MULE transposase domain
MHFCAHFK_02678 4.86e-99 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MHFCAHFK_02679 1.15e-112 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MHFCAHFK_02680 9.77e-48 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHFCAHFK_02681 7.52e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MHFCAHFK_02682 4.87e-166 ycsI - - S - - - Protein of unknown function (DUF1445)
MHFCAHFK_02683 2.91e-140 - - - S ko:K07160 - ko00000 LamB/YcsF family
MHFCAHFK_02684 8.53e-234 ycsG - - P - - - Natural resistance-associated macrophage protein
MHFCAHFK_02685 3.64e-45 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHFCAHFK_02686 3.34e-305 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
MHFCAHFK_02687 9.49e-197 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MHFCAHFK_02688 3.95e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHFCAHFK_02689 2.06e-125 - - - L - - - Resolvase, N terminal domain
MHFCAHFK_02690 1.15e-77 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_02691 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHFCAHFK_02692 6.28e-45 - - - M - - - LysM domain protein
MHFCAHFK_02694 9.33e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_02695 1.64e-47 - - - EGP - - - Major facilitator Superfamily
MHFCAHFK_02696 3.65e-119 - - - EGP ko:K08164 - ko00000,ko02000 Transporter
MHFCAHFK_02697 3.43e-236 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MHFCAHFK_02698 8.55e-307 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHFCAHFK_02699 6.96e-20 - - - S - - - Transglycosylase associated protein
MHFCAHFK_02701 1.53e-80 - - - S - - - Domain of unknown function (DUF4355)
MHFCAHFK_02702 2.19e-103 gpG - - - - - - -
MHFCAHFK_02703 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHFCAHFK_02705 2.39e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MHFCAHFK_02706 4.71e-61 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHFCAHFK_02707 3.08e-26 - - - - - - - -
MHFCAHFK_02708 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHFCAHFK_02709 1.4e-171 repA - - S - - - Replication initiator protein A
MHFCAHFK_02710 1.88e-23 - - - - - - - -
MHFCAHFK_02711 7.14e-53 - - - S - - - protein conserved in bacteria
MHFCAHFK_02712 4.54e-54 - - - - - - - -
MHFCAHFK_02714 4.41e-316 - - - EGP - - - Major Facilitator
MHFCAHFK_02715 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHFCAHFK_02716 4.26e-109 cvpA - - S - - - Colicin V production protein
MHFCAHFK_02717 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHFCAHFK_02718 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MHFCAHFK_02719 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MHFCAHFK_02720 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHFCAHFK_02721 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MHFCAHFK_02722 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MHFCAHFK_02723 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHFCAHFK_02725 2.77e-30 - - - - - - - -
MHFCAHFK_02727 6.62e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
MHFCAHFK_02728 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MHFCAHFK_02729 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_02730 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MHFCAHFK_02731 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MHFCAHFK_02732 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MHFCAHFK_02733 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MHFCAHFK_02734 1.54e-228 ydbI - - K - - - AI-2E family transporter
MHFCAHFK_02735 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHFCAHFK_02736 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHFCAHFK_02738 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
MHFCAHFK_02739 1.88e-106 - - - - - - - -
MHFCAHFK_02741 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHFCAHFK_02742 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHFCAHFK_02743 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHFCAHFK_02744 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHFCAHFK_02745 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHFCAHFK_02746 2.49e-73 - - - S - - - Enterocin A Immunity
MHFCAHFK_02747 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHFCAHFK_02748 1.67e-250 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MHFCAHFK_02749 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
MHFCAHFK_02750 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MHFCAHFK_02751 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MHFCAHFK_02752 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MHFCAHFK_02753 1.03e-34 - - - - - - - -
MHFCAHFK_02754 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
MHFCAHFK_02755 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MHFCAHFK_02756 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MHFCAHFK_02757 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
MHFCAHFK_02758 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MHFCAHFK_02759 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
MHFCAHFK_02760 1.28e-77 - - - S - - - Enterocin A Immunity
MHFCAHFK_02761 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHFCAHFK_02762 3.32e-135 - - - - - - - -
MHFCAHFK_02763 8.44e-304 - - - S - - - module of peptide synthetase
MHFCAHFK_02764 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
MHFCAHFK_02766 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MHFCAHFK_02767 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_02768 6.46e-201 - - - GM - - - NmrA-like family
MHFCAHFK_02769 4.08e-101 - - - K - - - MerR family regulatory protein
MHFCAHFK_02770 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHFCAHFK_02771 1.03e-21 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
MHFCAHFK_02772 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_02773 4.72e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
MHFCAHFK_02774 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
MHFCAHFK_02775 7.41e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MHFCAHFK_02776 1.44e-189 - - - S - - - haloacid dehalogenase-like hydrolase
MHFCAHFK_02777 1.14e-195 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MHFCAHFK_02778 6.26e-101 - - - - - - - -
MHFCAHFK_02779 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHFCAHFK_02780 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHFCAHFK_02781 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHFCAHFK_02782 1.07e-262 - - - S - - - DUF218 domain
MHFCAHFK_02783 6.39e-234 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHFCAHFK_02784 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHFCAHFK_02785 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHFCAHFK_02786 2.48e-204 - - - S - - - Putative adhesin
MHFCAHFK_02787 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
MHFCAHFK_02788 1.72e-69 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
MHFCAHFK_02789 2.08e-125 - - - KT - - - response to antibiotic
MHFCAHFK_02790 1.2e-175 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHFCAHFK_02792 3.84e-203 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_02793 1.32e-112 - - - K - - - Domain of unknown function (DUF1836)
MHFCAHFK_02794 1.18e-192 degV - - S - - - Uncharacterised protein, DegV family COG1307
MHFCAHFK_02795 2.28e-57 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MHFCAHFK_02796 1.45e-237 - - - S - - - Bacteriophage abortive infection AbiH
MHFCAHFK_02797 4.67e-179 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MHFCAHFK_02798 4.86e-199 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHFCAHFK_02799 2.85e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MHFCAHFK_02800 4.06e-78 - - - K - - - Psort location Cytoplasmic, score
MHFCAHFK_02801 2.4e-202 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_02803 3.31e-52 - - - L ko:K07483 - ko00000 Transposase
MHFCAHFK_02804 3.69e-46 - - - L - - - 4.5 Transposon and IS
MHFCAHFK_02805 6.5e-69 - - - L ko:K07482 - ko00000 Integrase core domain
MHFCAHFK_02806 2.59e-56 - - - S - - - SIR2-like domain
MHFCAHFK_02807 4.03e-64 - - - S ko:K06915 - ko00000 cog cog0433
MHFCAHFK_02809 4.22e-143 - - - L - - - Psort location Cytoplasmic, score
MHFCAHFK_02810 1.86e-90 - - - L - - - Psort location Cytoplasmic, score
MHFCAHFK_02811 5.3e-44 - - - - - - - -
MHFCAHFK_02812 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_02813 0.0 - - - L - - - MobA MobL family protein
MHFCAHFK_02814 3.02e-05 - - - - - - - -
MHFCAHFK_02815 2.85e-53 - - - - - - - -
MHFCAHFK_02816 1.62e-52 - - - S - - - protein conserved in bacteria
MHFCAHFK_02817 1.95e-25 - - - - - - - -
MHFCAHFK_02818 6.99e-76 - - - - - - - -
MHFCAHFK_02820 1.76e-189 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
MHFCAHFK_02821 1.57e-14 atzC 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
MHFCAHFK_02822 1.09e-295 cps4J - - S - - - MatE
MHFCAHFK_02823 7.07e-249 - - - E - - - Asparagine synthase
MHFCAHFK_02824 1.46e-97 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
MHFCAHFK_02825 2.05e-297 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHFCAHFK_02826 4.32e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MHFCAHFK_02827 4e-242 - - - S - - - EpsG family
MHFCAHFK_02828 1.21e-112 cps4I - - M - - - Glycosyltransferase like family 2
MHFCAHFK_02829 6.27e-270 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_02830 1.44e-154 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHFCAHFK_02831 4.39e-175 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHFCAHFK_02832 2.65e-160 ywqD - - D - - - Capsular exopolysaccharide family
MHFCAHFK_02833 4.19e-166 epsB - - M - - - biosynthesis protein
MHFCAHFK_02834 1.86e-214 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_02835 2.86e-43 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHFCAHFK_02836 3.86e-68 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MHFCAHFK_02837 9.95e-73 - - - L - - - Integrase
MHFCAHFK_02838 6.92e-281 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MHFCAHFK_02839 2.99e-11 - - - - - - - -
MHFCAHFK_02840 1.88e-43 - - - - - - - -
MHFCAHFK_02841 1.87e-137 - - - K - - - Bacterial regulatory proteins, tetR family
MHFCAHFK_02842 0.0 - - - EGP - - - Major Facilitator
MHFCAHFK_02843 1.22e-231 - - - S - - - Fic/DOC family
MHFCAHFK_02844 1.12e-46 - - - Q - - - ubiE/COQ5 methyltransferase family
MHFCAHFK_02845 1.58e-91 - - - L - - - Integrase
MHFCAHFK_02846 8.89e-31 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
MHFCAHFK_02847 1.76e-147 - - - EGP - - - Transmembrane secretion effector
MHFCAHFK_02849 4.59e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHFCAHFK_02850 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHFCAHFK_02851 1.02e-155 - - - S - - - repeat protein
MHFCAHFK_02852 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
MHFCAHFK_02853 0.0 - - - N - - - domain, Protein
MHFCAHFK_02854 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
MHFCAHFK_02855 5.92e-153 - - - N - - - WxL domain surface cell wall-binding
MHFCAHFK_02856 1.14e-148 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MHFCAHFK_02857 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MHFCAHFK_02858 6.7e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHFCAHFK_02859 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MHFCAHFK_02860 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHFCAHFK_02861 4.22e-51 - - - L - - - Transposase DDE domain
MHFCAHFK_02862 4.9e-39 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHFCAHFK_02863 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHFCAHFK_02864 7.74e-47 - - - - - - - -
MHFCAHFK_02865 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHFCAHFK_02866 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHFCAHFK_02867 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHFCAHFK_02868 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MHFCAHFK_02869 2.06e-187 ylmH - - S - - - S4 domain protein
MHFCAHFK_02870 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MHFCAHFK_02871 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHFCAHFK_02872 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHFCAHFK_02873 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHFCAHFK_02874 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHFCAHFK_02875 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHFCAHFK_02876 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHFCAHFK_02877 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHFCAHFK_02878 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHFCAHFK_02879 7.01e-76 ftsL - - D - - - Cell division protein FtsL
MHFCAHFK_02880 2.58e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHFCAHFK_02881 1.14e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHFCAHFK_02882 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
MHFCAHFK_02883 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHFCAHFK_02884 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHFCAHFK_02885 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHFCAHFK_02886 1.76e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MHFCAHFK_02887 8.82e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHFCAHFK_02889 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MHFCAHFK_02890 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHFCAHFK_02891 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
MHFCAHFK_02892 1.55e-74 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHFCAHFK_02893 1.6e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MHFCAHFK_02894 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MHFCAHFK_02895 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHFCAHFK_02896 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHFCAHFK_02897 1.51e-155 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MHFCAHFK_02898 2.24e-148 yjbH - - Q - - - Thioredoxin
MHFCAHFK_02899 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHFCAHFK_02900 7.52e-263 coiA - - S ko:K06198 - ko00000 Competence protein
MHFCAHFK_02901 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHFCAHFK_02902 5.37e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHFCAHFK_02903 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
MHFCAHFK_02904 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MHFCAHFK_02924 2.68e-71 - - - M - - - domain protein
MHFCAHFK_02925 1.17e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MHFCAHFK_02926 4.43e-129 - - - - - - - -
MHFCAHFK_02927 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHFCAHFK_02928 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
MHFCAHFK_02929 1.03e-76 - - - K - - - LysR substrate binding domain
MHFCAHFK_02930 1.28e-138 - - - K - - - LysR substrate binding domain
MHFCAHFK_02931 5.67e-232 - - - M - - - Peptidase family S41
MHFCAHFK_02932 2.24e-277 - - - - - - - -
MHFCAHFK_02933 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHFCAHFK_02934 0.0 yhaN - - L - - - AAA domain
MHFCAHFK_02935 5e-293 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MHFCAHFK_02936 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
MHFCAHFK_02937 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHFCAHFK_02938 2.43e-18 - - - - - - - -
MHFCAHFK_02939 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHFCAHFK_02940 9.65e-272 arcT - - E - - - Aminotransferase
MHFCAHFK_02941 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
MHFCAHFK_02942 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
MHFCAHFK_02943 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHFCAHFK_02944 2.01e-147 yciB - - M - - - ErfK YbiS YcfS YnhG
MHFCAHFK_02945 1.1e-70 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MHFCAHFK_02946 1.14e-191 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MHFCAHFK_02947 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHFCAHFK_02948 2.4e-284 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFCAHFK_02949 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHFCAHFK_02950 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHFCAHFK_02951 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
MHFCAHFK_02952 0.0 celR - - K - - - PRD domain
MHFCAHFK_02953 4.45e-164 celR - - K - - - PRD domain
MHFCAHFK_02954 6.25e-138 - - - - - - - -
MHFCAHFK_02955 5.45e-274 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHFCAHFK_02956 2.68e-162 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHFCAHFK_02957 3.81e-105 - - - - - - - -
MHFCAHFK_02958 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHFCAHFK_02959 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
MHFCAHFK_02962 1.79e-42 - - - - - - - -
MHFCAHFK_02963 2.69e-316 dinF - - V - - - MatE
MHFCAHFK_02964 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
MHFCAHFK_02965 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MHFCAHFK_02966 5.68e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
MHFCAHFK_02967 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MHFCAHFK_02968 7.32e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MHFCAHFK_02969 0.0 - - - S - - - Protein conserved in bacteria
MHFCAHFK_02970 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHFCAHFK_02971 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHFCAHFK_02972 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
MHFCAHFK_02973 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
MHFCAHFK_02974 3.89e-237 - - - - - - - -
MHFCAHFK_02975 5.24e-15 - - - - - - - -
MHFCAHFK_02976 4.29e-87 - - - - - - - -
MHFCAHFK_02978 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHFCAHFK_02979 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHFCAHFK_02980 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFCAHFK_02981 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFCAHFK_02982 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHFCAHFK_02983 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
MHFCAHFK_02984 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
MHFCAHFK_02985 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
MHFCAHFK_02986 1.49e-252 - - - M - - - MucBP domain
MHFCAHFK_02987 0.0 - - - - - - - -
MHFCAHFK_02988 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHFCAHFK_02989 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHFCAHFK_02990 1e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MHFCAHFK_02991 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MHFCAHFK_02992 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MHFCAHFK_02993 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MHFCAHFK_02994 1.13e-257 yueF - - S - - - AI-2E family transporter
MHFCAHFK_02995 4.22e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHFCAHFK_02997 5.41e-163 pbpX - - V - - - Beta-lactamase
MHFCAHFK_02998 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
MHFCAHFK_02999 2.27e-13 - - - K - - - sequence-specific DNA binding
MHFCAHFK_03000 8.38e-43 - - - K - - - sequence-specific DNA binding
MHFCAHFK_03001 9.64e-171 lytE - - M - - - NlpC/P60 family
MHFCAHFK_03002 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHFCAHFK_03003 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MHFCAHFK_03004 3.29e-169 - - - - - - - -
MHFCAHFK_03005 4.14e-132 - - - K - - - DNA-templated transcription, initiation
MHFCAHFK_03006 8.39e-38 - - - - - - - -
MHFCAHFK_03007 1.95e-41 - - - - - - - -
MHFCAHFK_03008 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
MHFCAHFK_03009 9.02e-70 - - - - - - - -
MHFCAHFK_03010 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHFCAHFK_03011 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MHFCAHFK_03012 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_03013 0.0 - - - M - - - domain protein
MHFCAHFK_03014 2.39e-175 - - - K - - - helix_turn_helix, arabinose operon control protein
MHFCAHFK_03015 8.42e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
MHFCAHFK_03016 5.06e-260 cps3I - - G - - - Acyltransferase family
MHFCAHFK_03017 4.9e-263 cps3H - - - - - - -
MHFCAHFK_03018 2e-206 cps3F - - - - - - -
MHFCAHFK_03019 1.69e-144 cps3E - - - - - - -
MHFCAHFK_03020 1.6e-259 cps3D - - - - - - -
MHFCAHFK_03021 2.81e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MHFCAHFK_03022 1.56e-227 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MHFCAHFK_03023 2.45e-170 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MHFCAHFK_03025 6.17e-71 - - - S - - - SMI1-KNR4 cell-wall
MHFCAHFK_03027 2.05e-32 - - - S - - - Barstar (barnase inhibitor)
MHFCAHFK_03030 6.56e-22 - - - N - - - Cell shape-determining protein MreB
MHFCAHFK_03031 0.0 - - - S - - - Pfam Methyltransferase
MHFCAHFK_03032 1.25e-207 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_03033 8.82e-125 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_03034 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_03035 9.32e-40 - - - - - - - -
MHFCAHFK_03036 3.54e-121 mraW1 - - J - - - Putative rRNA methylase
MHFCAHFK_03037 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHFCAHFK_03038 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHFCAHFK_03039 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHFCAHFK_03040 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHFCAHFK_03041 1.83e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHFCAHFK_03042 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MHFCAHFK_03043 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
MHFCAHFK_03044 4.15e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MHFCAHFK_03045 4.59e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHFCAHFK_03046 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHFCAHFK_03047 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHFCAHFK_03048 1.56e-161 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHFCAHFK_03049 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
MHFCAHFK_03050 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHFCAHFK_03051 7.61e-316 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MHFCAHFK_03053 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MHFCAHFK_03054 2.06e-98 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_03055 3.45e-83 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHFCAHFK_03056 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
MHFCAHFK_03057 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHFCAHFK_03058 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
MHFCAHFK_03059 1.64e-151 - - - GM - - - NAD(P)H-binding
MHFCAHFK_03060 9.36e-205 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHFCAHFK_03061 1.14e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHFCAHFK_03062 7.83e-140 - - - - - - - -
MHFCAHFK_03063 5.95e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MHFCAHFK_03064 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHFCAHFK_03065 5.37e-74 - - - - - - - -
MHFCAHFK_03066 4.56e-78 - - - - - - - -
MHFCAHFK_03067 4.31e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHFCAHFK_03068 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MHFCAHFK_03069 8.82e-119 - - - - - - - -
MHFCAHFK_03070 7.12e-62 - - - - - - - -
MHFCAHFK_03071 0.0 uvrA2 - - L - - - ABC transporter
MHFCAHFK_03074 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MHFCAHFK_03075 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
MHFCAHFK_03079 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
MHFCAHFK_03080 1.38e-71 - - - S - - - Cupin domain
MHFCAHFK_03081 3.62e-211 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MHFCAHFK_03082 1.59e-247 ysdE - - P - - - Citrate transporter
MHFCAHFK_03083 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MHFCAHFK_03084 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHFCAHFK_03085 8.37e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHFCAHFK_03086 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHFCAHFK_03087 2.31e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHFCAHFK_03088 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHFCAHFK_03089 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHFCAHFK_03090 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHFCAHFK_03091 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
MHFCAHFK_03092 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MHFCAHFK_03093 7.89e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHFCAHFK_03094 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHFCAHFK_03095 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHFCAHFK_03097 1e-200 - - - G - - - Peptidase_C39 like family
MHFCAHFK_03098 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHFCAHFK_03099 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MHFCAHFK_03100 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHFCAHFK_03101 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
MHFCAHFK_03102 2.74e-151 levR - - K - - - Sigma-54 interaction domain
MHFCAHFK_03103 0.0 levR - - K - - - Sigma-54 interaction domain
MHFCAHFK_03104 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHFCAHFK_03105 1.83e-112 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHFCAHFK_03106 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHFCAHFK_03107 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
MHFCAHFK_03108 4.82e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
MHFCAHFK_03109 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHFCAHFK_03110 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MHFCAHFK_03111 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHFCAHFK_03112 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MHFCAHFK_03113 6.04e-227 - - - EG - - - EamA-like transporter family
MHFCAHFK_03114 1.91e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHFCAHFK_03115 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
MHFCAHFK_03116 0.0 - 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 Cadmium transporter
MHFCAHFK_03117 2.06e-70 cadC - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_03118 2.35e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_03120 1.71e-70 - - - L - - - recombinase activity
MHFCAHFK_03121 0.0 - - - L ko:K07487 - ko00000 Transposase
MHFCAHFK_03122 5.25e-78 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHFCAHFK_03123 4.75e-272 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
MHFCAHFK_03124 3.32e-129 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MHFCAHFK_03125 1.26e-90 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MHFCAHFK_03126 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHFCAHFK_03127 4.64e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MHFCAHFK_03128 2.28e-223 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
MHFCAHFK_03129 5.55e-59 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
MHFCAHFK_03130 2.06e-125 - - - L - - - Resolvase, N terminal domain
MHFCAHFK_03131 3.21e-87 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MHFCAHFK_03132 3.52e-96 - - - L - - - Transposase DDE domain
MHFCAHFK_03133 8.73e-208 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MHFCAHFK_03135 3.09e-79 - - - EGP - - - Major Facilitator
MHFCAHFK_03136 2.87e-76 - - - S - - - Family of unknown function (DUF5388)
MHFCAHFK_03137 2.13e-188 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MHFCAHFK_03139 4.73e-66 repA - - S - - - Replication initiator protein A
MHFCAHFK_03140 2.83e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
MHFCAHFK_03141 6.43e-103 - - - - - - - -
MHFCAHFK_03142 1.03e-55 - - - - - - - -
MHFCAHFK_03143 6.89e-37 - - - - - - - -
MHFCAHFK_03144 0.0 - - - L - - - MobA MobL family protein
MHFCAHFK_03145 2.43e-49 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_03146 2.56e-279 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_03147 3.19e-45 - - - - - - - -
MHFCAHFK_03148 1.15e-134 - - - L - - - Psort location Cytoplasmic, score
MHFCAHFK_03149 2.19e-77 - - - L - - - Psort location Cytoplasmic, score
MHFCAHFK_03150 1.09e-178 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHFCAHFK_03151 3.3e-43 - - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHFCAHFK_03152 6.14e-226 arsB - - U ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHFCAHFK_03153 8.02e-198 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MHFCAHFK_03154 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MHFCAHFK_03155 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHFCAHFK_03156 8.95e-26 - - - - - - - -
MHFCAHFK_03157 5.3e-49 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHFCAHFK_03158 2.21e-84 - - - D - - - AAA domain
MHFCAHFK_03159 8.83e-06 - - - - - - - -
MHFCAHFK_03160 1.89e-145 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_03161 1.95e-45 ydaT - - - - - - -
MHFCAHFK_03163 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
MHFCAHFK_03164 2.06e-172 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_03165 3.58e-43 - - - L - - - transposase and inactivated derivatives, IS30 family
MHFCAHFK_03166 9.89e-87 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MHFCAHFK_03167 4.71e-192 tra981A - - L ko:K07497 - ko00000 Integrase core domain
MHFCAHFK_03168 5.32e-53 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
MHFCAHFK_03170 2.37e-66 - - - M - - - Glycosyl transferase family 2
MHFCAHFK_03171 3.81e-120 wefC - - M - - - Stealth protein CR2, conserved region 2
MHFCAHFK_03172 2.79e-78 - - - S - - - Hexapeptide repeat of succinyl-transferase
MHFCAHFK_03173 5.35e-154 - - - M - - - Glycosyltransferase Family 4
MHFCAHFK_03174 4.13e-182 wchF - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
MHFCAHFK_03175 1.39e-120 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHFCAHFK_03176 2.86e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHFCAHFK_03177 9.56e-160 ywqD - - D - - - Capsular exopolysaccharide family
MHFCAHFK_03178 7.23e-165 epsB - - M - - - biosynthesis protein
MHFCAHFK_03179 9.73e-90 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHFCAHFK_03180 7.56e-183 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHFCAHFK_03181 2.7e-260 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHFCAHFK_03182 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MHFCAHFK_03183 5.11e-186 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHFCAHFK_03184 9.43e-279 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MHFCAHFK_03185 4.62e-224 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHFCAHFK_03186 6.33e-175 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHFCAHFK_03187 1.97e-307 traA - - L - - - MobA MobL family protein
MHFCAHFK_03188 3.69e-139 traA - - L - - - MobA MobL family protein
MHFCAHFK_03189 3.34e-52 - - - - - - - -
MHFCAHFK_03190 6.59e-159 - - - S - - - Fic/DOC family
MHFCAHFK_03191 5.22e-37 - - - - - - - -
MHFCAHFK_03192 7.07e-125 repA - - S - - - Replication initiator protein A
MHFCAHFK_03195 0.0 mdr - - EGP - - - Major Facilitator
MHFCAHFK_03196 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHFCAHFK_03197 5.79e-158 - - - - - - - -
MHFCAHFK_03198 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHFCAHFK_03199 3.91e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MHFCAHFK_03200 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHFCAHFK_03201 2.08e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MHFCAHFK_03202 8.01e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHFCAHFK_03204 1.7e-199 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHFCAHFK_03205 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
MHFCAHFK_03206 2.07e-123 - - - - - - - -
MHFCAHFK_03207 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
MHFCAHFK_03208 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
MHFCAHFK_03219 2.9e-255 glmS2 - - M - - - SIS domain
MHFCAHFK_03220 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHFCAHFK_03221 5.51e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MHFCAHFK_03222 4.21e-158 - - - S - - - YjbR
MHFCAHFK_03224 0.0 cadA - - P - - - P-type ATPase
MHFCAHFK_03225 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
MHFCAHFK_03226 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MHFCAHFK_03227 4.29e-101 - - - - - - - -
MHFCAHFK_03228 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MHFCAHFK_03229 1.32e-72 - - - FG - - - HIT domain
MHFCAHFK_03230 1.66e-40 - - - FG - - - HIT domain
MHFCAHFK_03231 1.05e-223 ydhF - - S - - - Aldo keto reductase
MHFCAHFK_03232 8.93e-71 - - - S - - - Pfam:DUF59
MHFCAHFK_03233 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHFCAHFK_03234 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MHFCAHFK_03235 1.87e-249 - - - V - - - Beta-lactamase
MHFCAHFK_03236 3.74e-125 - - - V - - - VanZ like family
MHFCAHFK_03237 4.5e-147 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
MHFCAHFK_03238 1.42e-90 dam 2.1.1.72 - L ko:K07318 - ko00000,ko01000,ko02048 D12 class N6 adenine-specific DNA methyltransferase
MHFCAHFK_03239 4.29e-105 - - - L - - - AlwI restriction endonuclease
MHFCAHFK_03240 3.45e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHFCAHFK_03241 1.02e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
MHFCAHFK_03242 3.92e-141 - - - L - - - Integrase
MHFCAHFK_03243 3.42e-141 - - - - - - - -
MHFCAHFK_03244 6.62e-245 - - - S - - - MobA/MobL family
MHFCAHFK_03247 1.8e-38 - - - - - - - -
MHFCAHFK_03248 2.74e-149 - - - L - - - Initiator Replication protein
MHFCAHFK_03249 1.16e-69 - - - - - - - -
MHFCAHFK_03250 1.26e-76 - - - L - - - Caulimovirus viroplasmin
MHFCAHFK_03252 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
MHFCAHFK_03253 1.29e-195 is18 - - L - - - Integrase core domain
MHFCAHFK_03254 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHFCAHFK_03255 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
MHFCAHFK_03256 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHFCAHFK_03257 1.88e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHFCAHFK_03258 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHFCAHFK_03259 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHFCAHFK_03260 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHFCAHFK_03261 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHFCAHFK_03262 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MHFCAHFK_03263 5.6e-41 - - - - - - - -
MHFCAHFK_03264 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHFCAHFK_03265 1.45e-131 - - - L - - - Integrase
MHFCAHFK_03266 3.4e-85 - - - K - - - Winged helix DNA-binding domain
MHFCAHFK_03267 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
MHFCAHFK_03268 0.0 nox - - C - - - NADH oxidase
MHFCAHFK_03269 2.6e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHFCAHFK_03270 4.95e-310 - - - - - - - -
MHFCAHFK_03271 6.83e-256 - - - S - - - Protein conserved in bacteria
MHFCAHFK_03272 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
MHFCAHFK_03273 0.0 - - - S - - - Bacterial cellulose synthase subunit
MHFCAHFK_03274 7.91e-172 - - - T - - - diguanylate cyclase activity
MHFCAHFK_03275 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHFCAHFK_03276 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
MHFCAHFK_03277 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
MHFCAHFK_03278 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHFCAHFK_03279 3.96e-44 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHFCAHFK_03280 3.59e-26 - - - - - - - -
MHFCAHFK_03282 1.98e-106 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MHFCAHFK_03283 2.95e-29 - - - L ko:K07482 - ko00000 Integrase core domain
MHFCAHFK_03284 2.09e-42 - - - - - - - -
MHFCAHFK_03285 3.78e-28 - - - - - - - -
MHFCAHFK_03286 1.53e-138 - - - L - - - Integrase
MHFCAHFK_03287 3.16e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
MHFCAHFK_03288 5.93e-14 - - - - - - - -
MHFCAHFK_03289 1.06e-158 - - - S - - - Plasmid replication protein
MHFCAHFK_03290 2.72e-135 mob - - D - - - Plasmid recombination enzyme
MHFCAHFK_03291 8.55e-28 - - - - - - - -
MHFCAHFK_03293 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MHFCAHFK_03294 4.06e-173 - - - L - - - Replication protein
MHFCAHFK_03295 2.88e-50 - - - L - - - Integrase core domain
MHFCAHFK_03296 1.68e-186 - - - L - - - Bacterial dnaA protein
MHFCAHFK_03297 2.08e-241 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
MHFCAHFK_03298 2.69e-226 - - - L ko:K07482 - ko00000 Integrase core domain
MHFCAHFK_03299 4.49e-74 - - - L - - - Transposase DDE domain
MHFCAHFK_03300 1.43e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)