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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PICBCKBE_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PICBCKBE_00002	7.56e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PICBCKBE_00003	5.78e-174	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PICBCKBE_00004	2.94e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
PICBCKBE_00005	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PICBCKBE_00006	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PICBCKBE_00007	3.04e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PICBCKBE_00008	2.69e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PICBCKBE_00009	6.81e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
PICBCKBE_00010	3.25e-192	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PICBCKBE_00011	1.58e-150	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PICBCKBE_00012	1.52e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
PICBCKBE_00013	2.94e-208	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
PICBCKBE_00014	3.73e-44	yyzM	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00015	1.51e-260	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PICBCKBE_00016	2.86e-267	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PICBCKBE_00017	4.32e-148	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PICBCKBE_00018	3.45e-284	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PICBCKBE_00019	3.83e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PICBCKBE_00020	3.01e-63	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PICBCKBE_00021	2.87e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PICBCKBE_00022	7.33e-50	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PICBCKBE_00023	9.26e-201	yybS	-	-	S	-	-	-	membrane
PICBCKBE_00024	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PICBCKBE_00025	9.21e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
PICBCKBE_00026	1.84e-316	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PICBCKBE_00027	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PICBCKBE_00030	5.26e-173	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_00031	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_00032	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00033	4.82e-181	yycI	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00034	7.14e-185	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PICBCKBE_00035	1.17e-273	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PICBCKBE_00036	1.48e-98	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PICBCKBE_00037	4.37e-05	-	-	-	S	ko:K07076	-	ko00000	DNA polymerase beta domain protein region
PICBCKBE_00039	1.04e-31	-	-	-	L	-	-	-	PFAM Integrase catalytic
PICBCKBE_00040	2.73e-54	-	-	-	L	-	-	-	Integrase core domain
PICBCKBE_00041	3.04e-92	-	-	-	L	-	-	-	Integrase core domain
PICBCKBE_00042	5.43e-47	-	-	-	L	-	-	-	IstB-like ATP binding protein
PICBCKBE_00043	3.62e-78	-	-	-	L	-	-	-	IstB-like ATP binding protein
PICBCKBE_00044	5.11e-290	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PICBCKBE_00045	2.56e-126	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00046	1.37e-115	-	-	-	E	-	-	-	LysE type translocator
PICBCKBE_00047	2.34e-151	XK27_07210	-	-	S	-	-	-	B3/4 domain
PICBCKBE_00049	1.16e-50	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_00050	4.08e-17	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
PICBCKBE_00052	4.33e-310	-	-	-	L	-	-	-	Mu transposase, C-terminal
PICBCKBE_00053	2.94e-194	-	-	-	U	-	-	-	AAA domain
PICBCKBE_00054	2.41e-87	-	-	-	-	-	-	-	-
PICBCKBE_00055	6.87e-205	tnp	-	-	L	ko:K07493	-	ko00000	transposase activity
PICBCKBE_00056	8.23e-125	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PICBCKBE_00057	7.63e-74	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
PICBCKBE_00058	8.95e-65	-	-	-	-	-	-	-	-
PICBCKBE_00059	2.18e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4405)
PICBCKBE_00060	6.87e-135	-	-	-	-	-	-	-	-
PICBCKBE_00061	3.38e-13	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
PICBCKBE_00062	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00063	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
PICBCKBE_00064	3.84e-107	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
PICBCKBE_00065	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PICBCKBE_00066	0.0	mqo	1.1.5.4	-	S	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	malate quinone oxidoreductase
PICBCKBE_00067	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_00068	4.13e-148	glnP9	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	amino acid ABC transporter
PICBCKBE_00069	6.79e-152	glnP7	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	amino acid ABC transporter
PICBCKBE_00070	5.85e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_00071	2.23e-196	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PICBCKBE_00072	5.02e-276	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
PICBCKBE_00073	5.09e-264	-	-	-	S	-	-	-	Domain of unknown function (DUF1611_N) Rossmann-like domain
PICBCKBE_00074	1.11e-287	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
PICBCKBE_00075	1.29e-305	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
PICBCKBE_00076	1.22e-135	glnQ2	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PICBCKBE_00077	4.15e-119	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Transporter
PICBCKBE_00078	3.96e-137	-	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PICBCKBE_00079	2.28e-191	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PICBCKBE_00080	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PICBCKBE_00081	4.67e-174	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
PICBCKBE_00082	4.71e-56	-	-	-	T	-	-	-	diguanylate cyclase activity
PICBCKBE_00083	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PICBCKBE_00084	0.0	-	-	-	S	ko:K06994,ko:K07003	-	ko00000	MMPL domain protein
PICBCKBE_00085	1.87e-127	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PICBCKBE_00086	4.46e-147	yhhQ_2	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PICBCKBE_00087	0.0	-	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PICBCKBE_00088	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_00089	4.29e-162	-	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PICBCKBE_00090	0.0	poxB	1.2.5.1	-	EH	ko:K00156	ko00620,map00620	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PICBCKBE_00091	1.79e-287	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
PICBCKBE_00092	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
PICBCKBE_00093	1.24e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PICBCKBE_00094	1.58e-197	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
PICBCKBE_00095	6.78e-306	yisQ	-	-	V	-	-	-	Mate efflux family protein
PICBCKBE_00096	1.11e-282	-	-	-	NU	ko:K18640	-	ko00000,ko04812	Pilus assembly protein
PICBCKBE_00097	5.36e-132	-	-	-	-	-	-	-	-
PICBCKBE_00098	8.38e-186	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PICBCKBE_00099	4.57e-245	metN_1	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PICBCKBE_00100	1.74e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
PICBCKBE_00101	2.71e-197	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PICBCKBE_00102	0.0	lytS	2.7.13.3	-	T	ko:K02478,ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_00103	3.01e-164	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
PICBCKBE_00104	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
PICBCKBE_00105	6.69e-264	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PICBCKBE_00106	5.6e-170	yjjP	-	-	S	-	-	-	Putative threonine/serine exporter
PICBCKBE_00107	3.75e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PICBCKBE_00108	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_00110	2.33e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF1646)
PICBCKBE_00111	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PICBCKBE_00112	3.16e-233	ywbI	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00113	4.35e-77	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
PICBCKBE_00114	1.43e-152	ywbG	-	-	M	-	-	-	effector of murein hydrolase
PICBCKBE_00116	7.86e-97	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PICBCKBE_00117	1.73e-19	-	-	-	-	-	-	-	-
PICBCKBE_00118	1.18e-195	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PICBCKBE_00119	4.69e-199	murR	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00120	7.04e-288	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
PICBCKBE_00121	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
PICBCKBE_00122	1.96e-223	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
PICBCKBE_00123	2.42e-169	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
PICBCKBE_00124	5.49e-82	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
PICBCKBE_00125	9.44e-194	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PICBCKBE_00126	1.06e-262	-	-	-	-	-	-	-	-
PICBCKBE_00128	3.12e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PICBCKBE_00129	6.72e-131	-	-	-	S	-	-	-	ABC-2 family transporter protein
PICBCKBE_00132	3.74e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_00133	7.25e-47	-	-	-	S	-	-	-	Stage II sporulation protein M
PICBCKBE_00134	0.0	-	-	-	-	-	-	-	-
PICBCKBE_00135	1.74e-26	-	-	-	S	-	-	-	Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
PICBCKBE_00136	3.71e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PICBCKBE_00137	5.51e-73	-	-	-	S	-	-	-	Heat induced stress protein YflT
PICBCKBE_00138	1.11e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PICBCKBE_00139	5.79e-52	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
PICBCKBE_00140	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
PICBCKBE_00141	1.26e-105	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PICBCKBE_00142	9.48e-188	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
PICBCKBE_00143	3.02e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
PICBCKBE_00144	2.4e-194	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PICBCKBE_00145	5.16e-139	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00147	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
PICBCKBE_00148	4.18e-118	ywgA	-	-	-	ko:K09388	-	ko00000	-
PICBCKBE_00149	2.69e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
PICBCKBE_00150	2.4e-152	ywhC	-	-	S	-	-	-	Peptidase M50
PICBCKBE_00151	3.07e-119	ywhD	-	-	S	-	-	-	YwhD family
PICBCKBE_00152	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PICBCKBE_00153	9.99e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
PICBCKBE_00154	4.59e-98	ywiB	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00155	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PICBCKBE_00156	1.24e-278	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PICBCKBE_00157	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
PICBCKBE_00158	9.36e-275	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
PICBCKBE_00159	6.5e-268	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
PICBCKBE_00160	1.6e-269	acdA	1.3.8.1, 1.3.8.7	-	I	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	acyl-CoA dehydrogenase
PICBCKBE_00161	3.71e-147	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00162	0.0	icmF	5.4.99.13	-	EI	ko:K11942	-	ko00000,ko01000	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PICBCKBE_00163	0.0	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PICBCKBE_00164	2.59e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_00165	4.48e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PICBCKBE_00166	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PICBCKBE_00167	3.35e-87	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PICBCKBE_00168	1.14e-159	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_00169	5.82e-186	-	-	-	-	-	-	-	-
PICBCKBE_00170	1.3e-262	-	-	-	-	-	-	-	-
PICBCKBE_00171	2.03e-80	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
PICBCKBE_00172	1.58e-203	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
PICBCKBE_00173	3.7e-149	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PICBCKBE_00174	5.13e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PICBCKBE_00175	1.74e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
PICBCKBE_00176	7.11e-293	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PICBCKBE_00177	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PICBCKBE_00178	4.8e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PICBCKBE_00180	1.48e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PICBCKBE_00181	2.62e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PICBCKBE_00182	1.87e-170	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
PICBCKBE_00183	1.66e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PICBCKBE_00184	2.27e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PICBCKBE_00185	5.54e-105	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PICBCKBE_00186	6.15e-269	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
PICBCKBE_00187	4.42e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
PICBCKBE_00188	1.13e-127	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PICBCKBE_00189	1.21e-304	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PICBCKBE_00190	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PICBCKBE_00191	1.92e-75	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
PICBCKBE_00192	4.65e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PICBCKBE_00193	1.21e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PICBCKBE_00194	2.3e-72	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PICBCKBE_00195	2.12e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PICBCKBE_00196	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PICBCKBE_00197	9.39e-196	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PICBCKBE_00198	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PICBCKBE_00199	1.03e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PICBCKBE_00200	1.1e-46	ywzB	-	-	S	-	-	-	membrane
PICBCKBE_00201	2.39e-174	ywmB	-	-	S	-	-	-	TATA-box binding
PICBCKBE_00202	2.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PICBCKBE_00203	4.86e-235	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
PICBCKBE_00204	7.35e-174	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
PICBCKBE_00205	3.27e-57	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
PICBCKBE_00206	4.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
PICBCKBE_00207	7.44e-186	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
PICBCKBE_00208	1.5e-192	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
PICBCKBE_00209	4.3e-96	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PICBCKBE_00211	5.41e-84	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
PICBCKBE_00212	3.69e-92	ywpF	-	-	S	-	-	-	YwpF-like protein
PICBCKBE_00214	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
PICBCKBE_00215	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
PICBCKBE_00216	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_00218	0.0	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PICBCKBE_00219	1.34e-108	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
PICBCKBE_00220	5.74e-301	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PICBCKBE_00221	5.71e-192	-	-	-	-	-	-	-	-
PICBCKBE_00222	9.1e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PICBCKBE_00223	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PICBCKBE_00224	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
PICBCKBE_00225	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
PICBCKBE_00226	6.56e-189	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
PICBCKBE_00227	1.19e-197	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
PICBCKBE_00228	8.65e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
PICBCKBE_00229	1.37e-310	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
PICBCKBE_00230	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
PICBCKBE_00231	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
PICBCKBE_00232	2.04e-227	yvdE	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00233	6.6e-158	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PICBCKBE_00234	3.56e-138	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
PICBCKBE_00235	7.99e-79	-	-	-	-	-	-	-	-
PICBCKBE_00236	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PICBCKBE_00237	3.46e-137	ydcA	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
PICBCKBE_00238	5.48e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PICBCKBE_00239	1.42e-244	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
PICBCKBE_00240	8.36e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PICBCKBE_00241	1.47e-55	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PICBCKBE_00242	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PICBCKBE_00243	1.24e-195	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
PICBCKBE_00244	3.41e-73	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
PICBCKBE_00245	5.15e-91	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PICBCKBE_00246	1.65e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
PICBCKBE_00247	5.11e-80	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
PICBCKBE_00248	8.05e-106	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PICBCKBE_00249	2.37e-176	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_00250	1.53e-139	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
PICBCKBE_00251	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
PICBCKBE_00252	3.79e-121	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PICBCKBE_00265	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_00266	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_00268	1.41e-108	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
PICBCKBE_00269	1.24e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
PICBCKBE_00270	1.35e-106	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PICBCKBE_00271	3.3e-236	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PICBCKBE_00272	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
PICBCKBE_00274	1.97e-159	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PICBCKBE_00275	2.26e-167	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PICBCKBE_00276	4.27e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4305)
PICBCKBE_00277	6.51e-161	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PICBCKBE_00278	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PICBCKBE_00279	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PICBCKBE_00280	1.5e-88	yngA	-	-	S	-	-	-	GtrA-like protein
PICBCKBE_00281	1.84e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
PICBCKBE_00282	0.0	ykoS	-	-	-	-	-	-	-
PICBCKBE_00283	3.02e-254	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PICBCKBE_00284	1.14e-139	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
PICBCKBE_00285	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PICBCKBE_00286	7.49e-197	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PICBCKBE_00287	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PICBCKBE_00288	4.08e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
PICBCKBE_00289	9.48e-43	-	-	-	-	-	-	-	-
PICBCKBE_00290	9.99e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
PICBCKBE_00291	5.26e-15	-	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_00292	6.11e-233	-	-	-	P	-	-	-	Major facilitator superfamily
PICBCKBE_00294	1.31e-121	-	-	-	-	-	-	-	-
PICBCKBE_00295	8.46e-242	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PICBCKBE_00296	6.61e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PICBCKBE_00297	1.25e-241	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PICBCKBE_00298	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
PICBCKBE_00299	2.91e-09	-	-	-	-	ko:K07213	ko04978,map04978	ko00000,ko00001	-
PICBCKBE_00300	2.28e-219	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_00301	1.78e-308	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PICBCKBE_00302	8.23e-247	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
PICBCKBE_00303	1.21e-48	yeeD	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PICBCKBE_00304	5.91e-209	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00305	4.87e-193	-	-	-	U	-	-	-	AAA domain
PICBCKBE_00306	0.0	-	-	-	L	-	-	-	Mu transposase, C-terminal
PICBCKBE_00308	1.17e-95	ywnA	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00309	1.83e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PICBCKBE_00310	4.4e-122	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
PICBCKBE_00311	7.06e-126	padR	-	-	K	-	-	-	transcriptional
PICBCKBE_00312	5.59e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00313	3.96e-163	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_00314	2.73e-163	-	-	-	-	-	-	-	-
PICBCKBE_00317	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PICBCKBE_00318	2.55e-64	-	-	-	L	-	-	-	deoxyribonuclease I activity
PICBCKBE_00319	0.0	citT_1	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PICBCKBE_00320	6.15e-287	-	1.13.11.4	-	Q	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	AraC-like ligand binding domain
PICBCKBE_00321	3.62e-210	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
PICBCKBE_00322	3.82e-183	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
PICBCKBE_00323	2.52e-283	-	-	-	EGP	ko:K05548	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
PICBCKBE_00324	6.71e-211	-	-	-	QT	-	-	-	Domain present in phytochromes and cGMP-specific phosphodiesterases.
PICBCKBE_00325	9.08e-201	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
PICBCKBE_00326	2.43e-42	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Enoyl-CoA hydratase/isomerase
PICBCKBE_00327	1.72e-121	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Enoyl-CoA hydratase/isomerase
PICBCKBE_00328	3.02e-275	thlA	2.3.1.16, 2.3.1.9	-	I	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PICBCKBE_00329	0.0	-	6.2.1.3, 6.2.1.34, 6.2.1.48	-	IQ	ko:K00666,ko:K01897,ko:K02182,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_00330	9.88e-91	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
PICBCKBE_00331	2.16e-194	-	1.14.13.127	-	CH	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	ko00000,ko00001,ko00002,ko01000	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PICBCKBE_00332	7.73e-74	-	-	-	-	-	-	-	-
PICBCKBE_00333	4.4e-173	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
PICBCKBE_00334	6.59e-227	-	3.7.1.5	-	Q	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PICBCKBE_00335	9.62e-116	-	-	-	S	-	-	-	DinB superfamily
PICBCKBE_00336	1.51e-287	-	1.13.11.4	-	Q	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	Cupin domain
PICBCKBE_00337	2.52e-262	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
PICBCKBE_00338	6.56e-253	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PICBCKBE_00339	3.91e-217	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
PICBCKBE_00340	9.7e-253	-	-	-	T	-	-	-	Histidine kinase
PICBCKBE_00341	2.8e-150	yfiK	-	-	K	-	-	-	Regulator
PICBCKBE_00342	2.47e-272	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_00343	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PICBCKBE_00344	0.000216	-	-	-	D	-	-	-	nuclear chromosome segregation
PICBCKBE_00345	3.52e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PICBCKBE_00346	3.05e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
PICBCKBE_00347	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_00348	7.54e-284	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PICBCKBE_00349	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_00350	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_00351	1.63e-239	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PICBCKBE_00352	3.37e-249	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
PICBCKBE_00353	8.32e-37	-	-	-	K	ko:K03481	-	ko00000,ko03000	SIS domain
PICBCKBE_00355	1.58e-54	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PICBCKBE_00356	4.55e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
PICBCKBE_00357	1.09e-117	yebE	-	-	S	-	-	-	UPF0316 protein
PICBCKBE_00358	1.37e-41	yebG	-	-	S	-	-	-	NETI protein
PICBCKBE_00359	1.06e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PICBCKBE_00360	3.47e-279	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PICBCKBE_00361	8.68e-316	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PICBCKBE_00362	2.77e-159	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PICBCKBE_00363	1.09e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PICBCKBE_00364	1.19e-160	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PICBCKBE_00365	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PICBCKBE_00366	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PICBCKBE_00367	4.06e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PICBCKBE_00368	6.71e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PICBCKBE_00369	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PICBCKBE_00370	2.16e-283	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PICBCKBE_00371	3.43e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
PICBCKBE_00372	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
PICBCKBE_00373	1.86e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
PICBCKBE_00374	7.4e-71	yerC	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00375	1.57e-167	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PICBCKBE_00376	3.83e-164	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	AAA domain
PICBCKBE_00377	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PICBCKBE_00378	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PICBCKBE_00379	1.64e-282	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
PICBCKBE_00380	0.0	aceB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the malate synthase family
PICBCKBE_00381	4.12e-313	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
PICBCKBE_00382	2.67e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PICBCKBE_00383	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PICBCKBE_00384	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PICBCKBE_00386	4.74e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
PICBCKBE_00387	2.4e-246	-	-	-	L	-	-	-	COG3039 Transposase and inactivated derivatives, IS5 family
PICBCKBE_00388	3.88e-199	-	-	-	Q	-	-	-	N-acetyltransferase
PICBCKBE_00390	1.95e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PICBCKBE_00391	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PICBCKBE_00392	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PICBCKBE_00393	4.74e-23	yxjI	-	-	S	-	-	-	LURP-one-related
PICBCKBE_00394	6.27e-49	yxjI	-	-	S	-	-	-	LURP-one-related
PICBCKBE_00395	3.34e-244	-	-	-	-	-	-	-	-
PICBCKBE_00396	1.65e-122	-	-	-	S	-	-	-	S4 RNA-binding domain
PICBCKBE_00397	1.05e-68	-	-	-	Q	-	-	-	Isochorismatase family
PICBCKBE_00399	7.04e-13	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
PICBCKBE_00400	7.39e-56	-	-	-	K	ko:K19505	-	ko00000,ko03000	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PICBCKBE_00401	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	PTS system fructose IIA component
PICBCKBE_00402	1.51e-138	-	-	-	K	ko:K19505	-	ko00000,ko03000	PFAM sigma-54 factor interaction domain-containing protein
PICBCKBE_00403	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_00404	9.99e-93	-	-	-	G	-	-	-	PTS system fructose IIA component
PICBCKBE_00405	4.66e-60	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PICBCKBE_00406	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00407	1.22e-30	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PICBCKBE_00408	1.59e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PICBCKBE_00409	4.27e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PFAM Phosphotransferase system, mannose fructose sorbose family IID component
PICBCKBE_00410	4.65e-56	-	-	-	-	-	-	-	-
PICBCKBE_00411	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00412	0.0	-	-	-	-	-	-	-	-
PICBCKBE_00413	3.63e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
PICBCKBE_00414	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_00415	3.19e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
PICBCKBE_00416	2.25e-203	-	-	-	S	-	-	-	Protein of unknown function
PICBCKBE_00417	6.61e-182	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_00418	2.01e-140	-	-	-	EGP	-	-	-	Major Facilitator
PICBCKBE_00419	7.23e-28	mutR	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
PICBCKBE_00420	2.83e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
PICBCKBE_00421	2.25e-106	-	1.1.1.53	-	IQ	ko:K00038	ko00140,ko01100,map00140,map01100	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_00423	2.45e-246	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PICBCKBE_00424	8.27e-52	-	-	-	S	-	-	-	Nucleotidyltransferase domain
PICBCKBE_00425	2.2e-44	-	-	-	S	-	-	-	Protein of unknown function DUF86
PICBCKBE_00426	1.41e-264	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
PICBCKBE_00427	4.06e-146	-	-	-	M	-	-	-	Methyltransferase
PICBCKBE_00429	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00432	4.23e-115	-	-	-	E	-	-	-	Zn peptidase
PICBCKBE_00433	3.27e-10	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PICBCKBE_00434	2.03e-135	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_00435	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00437	3.34e-120	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
PICBCKBE_00438	6.6e-124	-	-	-	I	-	-	-	Domain of unknown function (DUF4430)
PICBCKBE_00439	2.14e-290	-	-	-	M	-	-	-	FFAT motif binding
PICBCKBE_00440	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
PICBCKBE_00441	2.13e-276	hipO3	-	-	S	ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
PICBCKBE_00442	2.89e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PICBCKBE_00443	1.13e-145	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
PICBCKBE_00444	8.99e-167	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PICBCKBE_00445	7.57e-103	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
PICBCKBE_00446	1.89e-274	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_00448	1.56e-169	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
PICBCKBE_00449	4.13e-230	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
PICBCKBE_00450	3.94e-173	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
PICBCKBE_00451	9.65e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
PICBCKBE_00452	2.83e-213	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
PICBCKBE_00453	3.17e-150	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PICBCKBE_00454	2.37e-290	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PICBCKBE_00455	6.29e-272	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PICBCKBE_00456	4.14e-164	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PICBCKBE_00457	4.09e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PICBCKBE_00458	8.61e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PICBCKBE_00459	1.03e-300	deoA	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
PICBCKBE_00460	1.39e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PICBCKBE_00461	1.74e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PICBCKBE_00462	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PICBCKBE_00463	3.47e-186	-	-	-	L	-	-	-	transposase mutator type
PICBCKBE_00464	3.69e-111	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
PICBCKBE_00465	1.45e-05	-	-	-	-	-	-	-	-
PICBCKBE_00466	9.16e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PICBCKBE_00467	1.52e-218	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PICBCKBE_00468	1.44e-275	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
PICBCKBE_00469	6.48e-166	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PICBCKBE_00470	1.97e-176	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
PICBCKBE_00471	1.62e-123	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
PICBCKBE_00472	2.26e-33	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
PICBCKBE_00473	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PICBCKBE_00474	4.15e-238	-	-	-	-	-	-	-	-
PICBCKBE_00475	0.0	-	-	-	V	-	-	-	COG1401 GTPase subunit of restriction endonuclease
PICBCKBE_00476	0.0	-	-	-	-	-	-	-	-
PICBCKBE_00477	1.33e-200	XK27_04815	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PICBCKBE_00479	1.97e-87	-	-	-	-	-	-	-	-
PICBCKBE_00480	4.1e-144	-	-	-	P	-	-	-	Integral membrane protein TerC family
PICBCKBE_00481	2.15e-52	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	belongs to the aldehyde dehydrogenase family
PICBCKBE_00482	4.79e-229	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PICBCKBE_00483	0.0	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PICBCKBE_00484	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
PICBCKBE_00485	4.06e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
PICBCKBE_00486	3.08e-107	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
PICBCKBE_00487	1.28e-77	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
PICBCKBE_00488	3.46e-157	cwlS	-	CBM50	M	ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PICBCKBE_00489	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00490	5.38e-142	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PICBCKBE_00491	1.99e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PICBCKBE_00492	0.0	yfiB	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PICBCKBE_00493	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PICBCKBE_00494	2.33e-98	-	-	-	-	-	-	-	-
PICBCKBE_00496	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_00497	2.89e-311	ybbC	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_00498	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_00499	0.0	estB	-	-	V	-	-	-	Belongs to the UPF0214 family
PICBCKBE_00500	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
PICBCKBE_00501	1.38e-207	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
PICBCKBE_00503	3.61e-185	-	-	-	G	-	-	-	Major Facilitator Superfamily
PICBCKBE_00504	5.37e-93	-	-	-	C	-	-	-	Taurine catabolism dioxygenase TauD, TfdA family
PICBCKBE_00505	1.22e-85	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PICBCKBE_00506	7.03e-40	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
PICBCKBE_00507	5.88e-277	-	2.3.1.179	-	IQ	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
PICBCKBE_00508	1.62e-297	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PICBCKBE_00510	2.7e-68	-	-	-	-	-	-	-	-
PICBCKBE_00511	0.0	-	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PICBCKBE_00512	3.69e-232	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
PICBCKBE_00513	9.07e-167	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
PICBCKBE_00514	9.85e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PICBCKBE_00515	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
PICBCKBE_00516	4.52e-140	-	-	-	S	-	-	-	Domain of unkown function (DUF1775)
PICBCKBE_00517	7e-220	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00518	4.11e-13	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00519	2.67e-116	-	-	-	S	-	-	-	Pyridoxamine 5'phosphate oxidase-like, FMN-binding
PICBCKBE_00520	2.12e-120	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00521	1.08e-67	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00522	5.3e-05	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00523	2.2e-06	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00526	8.31e-253	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
PICBCKBE_00527	2.25e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PICBCKBE_00528	3.65e-90	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PICBCKBE_00529	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PICBCKBE_00530	9.16e-197	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PICBCKBE_00531	2.3e-202	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
PICBCKBE_00533	6.29e-212	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate proton symporter
PICBCKBE_00534	1.76e-238	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PICBCKBE_00535	1.92e-89	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Sugar diacid utilization regulator
PICBCKBE_00536	4.06e-245	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
PICBCKBE_00537	9.23e-247	-	-	-	U	-	-	-	protein localization to endoplasmic reticulum
PICBCKBE_00538	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PICBCKBE_00539	3.53e-110	-	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	4Fe-4S single cluster domain
PICBCKBE_00540	1.05e-275	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PICBCKBE_00541	5.31e-151	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_00542	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_00543	1.84e-188	mleR	-	-	K	-	-	-	LysR substrate binding domain
PICBCKBE_00544	0.0	sfcA	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
PICBCKBE_00545	8.27e-25	mleP	-	-	S	ko:K07088	-	ko00000	auxin efflux carrier
PICBCKBE_00546	7.45e-144	mleP	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PICBCKBE_00548	1.27e-165	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PICBCKBE_00549	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_00550	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PICBCKBE_00551	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_00552	1.21e-103	crr	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
PICBCKBE_00553	6.36e-108	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
PICBCKBE_00554	1.38e-111	-	-	-	E	-	-	-	LysE type translocator
PICBCKBE_00555	2.19e-234	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PICBCKBE_00556	6.39e-34	-	-	-	O	-	-	-	Glutaredoxin-like domain (DUF836)
PICBCKBE_00557	9.12e-110	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PICBCKBE_00558	6.15e-124	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	amino acid
PICBCKBE_00559	5.73e-89	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PICBCKBE_00560	1.91e-117	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
PICBCKBE_00561	4.36e-129	tcyK	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	L-cystine-binding protein
PICBCKBE_00562	3.42e-133	-	-	-	ET	ko:K02030,ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
PICBCKBE_00563	2.07e-73	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PICBCKBE_00564	6.03e-48	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
PICBCKBE_00565	2.94e-115	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	Bacterial regulatory helix-turn-helix protein, lysR family
PICBCKBE_00566	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_00567	8.75e-174	cysK5	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
PICBCKBE_00568	1.05e-36	-	-	-	-	-	-	-	-
PICBCKBE_00571	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_00572	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00573	4.34e-41	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PICBCKBE_00574	5.44e-47	yxiG	-	-	-	-	-	-	-
PICBCKBE_00575	1.34e-51	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PICBCKBE_00576	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
PICBCKBE_00577	9.66e-132	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
PICBCKBE_00578	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PICBCKBE_00579	0.0	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	AAA domain (dynein-related subfamily)
PICBCKBE_00580	1.89e-252	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
PICBCKBE_00582	5.86e-33	-	-	-	-	-	-	-	-
PICBCKBE_00583	4.11e-71	-	-	-	M	-	-	-	SIS domain
PICBCKBE_00584	1.58e-207	fda	4.1.2.13	-	G	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	Belongs to the class I fructose-bisphosphate aldolase family
PICBCKBE_00585	3.89e-265	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
PICBCKBE_00586	3.24e-156	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
PICBCKBE_00587	2.17e-128	-	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
PICBCKBE_00588	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
PICBCKBE_00589	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PICBCKBE_00590	3.01e-58	-	-	-	-	-	-	-	-
PICBCKBE_00591	3.42e-69	-	-	-	-	-	-	-	-
PICBCKBE_00592	9.11e-92	-	-	-	S	-	-	-	Hemerythrin HHE cation binding domain
PICBCKBE_00593	1.68e-167	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
PICBCKBE_00594	9.55e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
PICBCKBE_00595	4.09e-145	ycfA	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_00596	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
PICBCKBE_00597	1.88e-307	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PICBCKBE_00598	5.61e-293	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
PICBCKBE_00600	3.66e-139	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
PICBCKBE_00601	3.67e-125	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PICBCKBE_00602	1.07e-80	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
PICBCKBE_00604	5.65e-172	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
PICBCKBE_00606	4.31e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
PICBCKBE_00607	7.1e-16	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_00608	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_00609	1.57e-214	-	-	-	G	ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_00610	2.87e-89	dhaL	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	S	ko:K00863,ko:K05879	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak2
PICBCKBE_00611	1.87e-158	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
PICBCKBE_00612	4.9e-43	-	2.2.1.10, 4.1.2.13	-	G	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	DeoC/LacD family aldolase
PICBCKBE_00613	7.41e-187	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
PICBCKBE_00614	5.48e-122	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Triosephosphate isomerase
PICBCKBE_00615	4.28e-121	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PICBCKBE_00616	0.0	pspF	-	-	KT	-	-	-	Transcriptional regulator
PICBCKBE_00617	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_00618	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	AMP-dependent synthetase
PICBCKBE_00619	2.89e-272	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
PICBCKBE_00620	4.61e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
PICBCKBE_00621	6.17e-22	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
PICBCKBE_00622	6.41e-207	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
PICBCKBE_00623	3.1e-172	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
PICBCKBE_00624	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PICBCKBE_00625	2.09e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PICBCKBE_00628	9.27e-127	-	-	-	O	-	-	-	HI0933-like protein
PICBCKBE_00630	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PICBCKBE_00631	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PICBCKBE_00632	1.89e-286	ywdJ	-	-	F	-	-	-	Xanthine uracil
PICBCKBE_00633	7.85e-216	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PICBCKBE_00635	1.71e-301	-	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_00636	6.35e-175	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
PICBCKBE_00638	2.63e-223	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PICBCKBE_00639	1.39e-231	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase DhaK, subunit
PICBCKBE_00640	1.64e-129	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PICBCKBE_00641	1.85e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PICBCKBE_00642	0.0	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PICBCKBE_00643	2.79e-176	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
PICBCKBE_00644	7.07e-97	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
PICBCKBE_00646	7.79e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PICBCKBE_00647	0.0	yfiG	-	-	U	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PICBCKBE_00648	2.04e-110	-	-	-	G	ko:K02755,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PICBCKBE_00649	1.16e-76	-	-	-	S	-	-	-	Nitrous oxide-stimulated promoter
PICBCKBE_00650	1.11e-195	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
PICBCKBE_00651	9.8e-124	-	-	-	D	-	-	-	Hemerythrin HHE cation binding
PICBCKBE_00652	2.13e-256	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
PICBCKBE_00653	7.36e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00654	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PICBCKBE_00655	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
PICBCKBE_00656	9.51e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
PICBCKBE_00657	1.89e-150	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PICBCKBE_00658	5.75e-242	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PICBCKBE_00659	7.63e-117	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
PICBCKBE_00660	7.6e-139	-	-	-	C	-	-	-	Nitroreductase family
PICBCKBE_00661	0.0	snf	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
PICBCKBE_00662	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Metal dependent phosphohydrolases with conserved 'HD' motif.
PICBCKBE_00663	1.11e-148	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
PICBCKBE_00664	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
PICBCKBE_00665	1.04e-172	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein
PICBCKBE_00666	3.35e-127	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	RecB family exonuclease
PICBCKBE_00667	4.43e-214	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PICBCKBE_00668	7.56e-52	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PICBCKBE_00669	4.86e-92	-	-	-	K	-	-	-	Transcriptional
PICBCKBE_00670	1.64e-141	gpmB	-	-	G	ko:K15640	-	ko00000	Histidine phosphatase superfamily (branch 1)
PICBCKBE_00671	1.67e-291	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PICBCKBE_00672	4.82e-276	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PICBCKBE_00673	9.99e-196	ypuA	-	-	S	-	-	-	Secreted protein
PICBCKBE_00674	5.33e-134	-	-	-	-	-	-	-	-
PICBCKBE_00675	2.92e-89	-	-	-	S	-	-	-	response to pH
PICBCKBE_00676	1.11e-139	-	-	-	-	-	-	-	-
PICBCKBE_00677	0.0	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
PICBCKBE_00679	1.45e-162	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
PICBCKBE_00681	1.22e-131	-	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
PICBCKBE_00682	1.4e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
PICBCKBE_00683	3.29e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PICBCKBE_00684	1.6e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
PICBCKBE_00685	8.59e-272	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PICBCKBE_00686	3.88e-116	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
PICBCKBE_00687	4.82e-248	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
PICBCKBE_00688	1.9e-232	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
PICBCKBE_00689	1.63e-110	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
PICBCKBE_00690	3.05e-186	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
PICBCKBE_00691	3.62e-287	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_00692	1.11e-77	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PICBCKBE_00694	3.26e-76	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
PICBCKBE_00695	1.21e-173	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
PICBCKBE_00696	1.3e-176	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
PICBCKBE_00697	1.92e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
PICBCKBE_00698	1.63e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
PICBCKBE_00699	1.12e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
PICBCKBE_00700	6.56e-189	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PICBCKBE_00701	8.75e-281	yfkF	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_00702	1.01e-231	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
PICBCKBE_00704	1.34e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
PICBCKBE_00705	2.58e-37	yfjT	-	-	-	-	-	-	-
PICBCKBE_00706	1.57e-187	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
PICBCKBE_00707	1.33e-196	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PICBCKBE_00708	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PICBCKBE_00709	4.71e-56	-	-	-	-	-	-	-	-
PICBCKBE_00710	1.24e-130	-	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
PICBCKBE_00711	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PICBCKBE_00714	0.0	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PICBCKBE_00716	8.01e-77	-	-	-	-	-	-	-	-
PICBCKBE_00717	3.32e-240	fabH5	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
PICBCKBE_00718	4.04e-204	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PICBCKBE_00719	1.62e-187	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PICBCKBE_00720	4.5e-66	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PICBCKBE_00721	3.47e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PICBCKBE_00722	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
PICBCKBE_00723	3.02e-44	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
PICBCKBE_00724	9.58e-117	-	-	-	S	-	-	-	AAA domain
PICBCKBE_00725	1.04e-112	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
PICBCKBE_00726	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
PICBCKBE_00727	3.22e-98	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
PICBCKBE_00728	2.08e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PICBCKBE_00729	4.88e-79	-	-	-	-	ko:K06327	-	ko00000	-
PICBCKBE_00730	9.63e-100	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
PICBCKBE_00731	8.52e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00732	2.24e-202	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
PICBCKBE_00733	1.33e-270	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PICBCKBE_00735	2.66e-112	-	-	-	-	-	-	-	-
PICBCKBE_00736	0.0	-	-	-	S	-	-	-	Protein of unknown function N-terminus (DUF3323)
PICBCKBE_00737	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
PICBCKBE_00738	3.36e-295	-	-	-	S	-	-	-	Protein of unknown function (DUF2398)
PICBCKBE_00739	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2397)
PICBCKBE_00740	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
PICBCKBE_00741	4.07e-138	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00742	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
PICBCKBE_00745	1.08e-248	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
PICBCKBE_00746	0.0	ypdA3	2.7.13.3	-	T	ko:K02478,ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
PICBCKBE_00747	2.21e-176	-	-	-	T	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
PICBCKBE_00748	5.46e-279	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major facilitator superfamily
PICBCKBE_00749	1.73e-271	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
PICBCKBE_00750	4.99e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PICBCKBE_00751	0.0	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
PICBCKBE_00752	1.37e-308	-	-	-	-	-	-	-	-
PICBCKBE_00753	9e-194	rsbRD	-	-	T	ko:K17763	-	ko00000,ko03021	STAS domain
PICBCKBE_00754	3.55e-312	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PICBCKBE_00755	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
PICBCKBE_00756	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
PICBCKBE_00757	1.9e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
PICBCKBE_00758	1.27e-249	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PICBCKBE_00759	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PICBCKBE_00760	2.51e-259	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PICBCKBE_00761	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PICBCKBE_00762	6.51e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PICBCKBE_00763	6.24e-245	tdcB_1	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PICBCKBE_00764	3.55e-280	-	-	-	S	-	-	-	HAD-hyrolase-like
PICBCKBE_00765	1.1e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PICBCKBE_00766	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PICBCKBE_00767	1.34e-280	sgaA	-	-	E	-	-	-	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PICBCKBE_00768	9.45e-234	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PICBCKBE_00769	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PICBCKBE_00771	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PICBCKBE_00772	3.37e-273	-	-	-	Q	-	-	-	Male sterility protein
PICBCKBE_00773	8.68e-168	-	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PICBCKBE_00774	2.97e-210	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
PICBCKBE_00776	8.25e-47	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_00777	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_00778	3.4e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PICBCKBE_00780	7.15e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PICBCKBE_00781	2.3e-80	-	-	-	-	-	-	-	-
PICBCKBE_00783	4.79e-35	-	-	-	-	-	-	-	-
PICBCKBE_00784	0.0	-	-	-	-	-	-	-	-
PICBCKBE_00786	1.48e-62	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
PICBCKBE_00788	6.86e-163	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PICBCKBE_00789	1.29e-113	-	-	-	S	-	-	-	Stage II sporulation protein M
PICBCKBE_00790	5.35e-12	-	-	-	-	-	-	-	-
PICBCKBE_00792	8.15e-242	bacG	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PICBCKBE_00793	7.71e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_00794	2.23e-262	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
PICBCKBE_00795	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PICBCKBE_00796	6.22e-140	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase
PICBCKBE_00797	2.92e-234	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PICBCKBE_00798	0.0	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
PICBCKBE_00799	7.62e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PICBCKBE_00801	3.41e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PICBCKBE_00802	4.9e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
PICBCKBE_00803	1.73e-07	-	-	-	S	-	-	-	YfhE-like protein
PICBCKBE_00804	2.34e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
PICBCKBE_00805	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_00806	3.34e-67	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
PICBCKBE_00807	5.62e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
PICBCKBE_00808	4.2e-240	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
PICBCKBE_00809	3.91e-31	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
PICBCKBE_00810	1.01e-195	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PICBCKBE_00811	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_00812	1.06e-67	-	-	-	S	-	-	-	ABC-2 family transporter protein
PICBCKBE_00813	1.39e-46	-	-	-	S	-	-	-	ABC-2 family transporter protein
PICBCKBE_00814	9.57e-59	-	-	-	S	-	-	-	YfzA-like protein
PICBCKBE_00815	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PICBCKBE_00816	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
PICBCKBE_00817	1.52e-212	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_00818	1.13e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_00819	2.95e-23	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
PICBCKBE_00820	4.1e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
PICBCKBE_00821	5.7e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PICBCKBE_00822	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
PICBCKBE_00823	4.39e-270	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PICBCKBE_00824	1.74e-196	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PICBCKBE_00825	0.0	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_00826	5.92e-201	yleF	-	-	K	-	-	-	transcriptional
PICBCKBE_00827	5.71e-241	ygaE	-	-	S	-	-	-	Membrane
PICBCKBE_00828	1.41e-53	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
PICBCKBE_00829	2.57e-80	-	-	-	-	-	-	-	-
PICBCKBE_00830	7.1e-292	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_00831	7.17e-146	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PICBCKBE_00832	1.5e-185	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PICBCKBE_00833	5.87e-182	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PICBCKBE_00834	4.73e-241	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PICBCKBE_00835	3.19e-315	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
PICBCKBE_00836	1.04e-86	-	-	-	P	ko:K08713	-	ko00000,ko02000	Ion transport
PICBCKBE_00837	3.81e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
PICBCKBE_00838	2.85e-107	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PICBCKBE_00839	1.16e-210	-	-	-	K	-	-	-	LysR substrate binding domain
PICBCKBE_00840	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PICBCKBE_00841	3.99e-179	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PICBCKBE_00842	3.29e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
PICBCKBE_00843	1.07e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
PICBCKBE_00844	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_00845	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_00861	4.12e-31	yetF3	-	-	K	-	-	-	membrane
PICBCKBE_00862	2.45e-39	yetF3	-	-	K	-	-	-	membrane
PICBCKBE_00863	5.12e-243	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PICBCKBE_00865	1.35e-263	adhC	1.1.1.1, 1.1.1.90	-	C	ko:K00001,ko:K00055	ko00010,ko00071,ko00350,ko00360,ko00622,ko00623,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00360,map00622,map00623,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
PICBCKBE_00866	1.44e-199	yxxF	-	-	EG	-	-	-	EamA-like transporter family
PICBCKBE_00867	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
PICBCKBE_00868	6.17e-156	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PICBCKBE_00869	1.33e-120	-	-	-	-	ko:K02004	-	ko00000,ko00002,ko02000	-
PICBCKBE_00870	1.64e-05	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_00871	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_00872	8.33e-64	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PICBCKBE_00873	1.37e-78	-	-	-	S	-	-	-	Predicted membrane protein (DUF2243)
PICBCKBE_00874	6.71e-109	-	-	-	S	ko:K02351	-	ko00000	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
PICBCKBE_00875	2.63e-301	-	-	-	L	-	-	-	Transposase DDE domain group 1
PICBCKBE_00876	1.36e-76	-	-	-	K	-	-	-	MarR family
PICBCKBE_00877	1.35e-64	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PICBCKBE_00878	2.79e-113	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PICBCKBE_00879	1.4e-83	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
PICBCKBE_00880	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_00881	4.03e-87	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PICBCKBE_00882	1.93e-20	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PICBCKBE_00883	4.84e-161	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
PICBCKBE_00884	4.39e-206	dtpT	-	-	E	ko:K03305	-	ko00000	POT family
PICBCKBE_00885	1.74e-65	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
PICBCKBE_00886	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_00887	9.23e-84	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
PICBCKBE_00888	3.04e-141	-	-	-	-	-	-	-	-
PICBCKBE_00889	0.0	ykoH	-	-	T	-	-	-	Histidine kinase
PICBCKBE_00890	4.85e-167	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_00891	2.63e-223	-	-	-	S	-	-	-	High confidence in function and specificity
PICBCKBE_00893	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_00895	3.08e-43	-	-	-	-	-	-	-	-
PICBCKBE_00896	1.01e-181	-	-	-	E	-	-	-	G-D-S-L family
PICBCKBE_00897	1.42e-215	bcrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_00898	2.02e-222	bcrB	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
PICBCKBE_00899	5.02e-117	-	-	-	-	-	-	-	-
PICBCKBE_00900	3.52e-130	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
PICBCKBE_00901	1.35e-184	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PICBCKBE_00902	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase
PICBCKBE_00903	4.81e-274	-	1.1.1.1	-	C	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PICBCKBE_00905	5.98e-209	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
PICBCKBE_00907	8.69e-193	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
PICBCKBE_00908	2.48e-171	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PICBCKBE_00909	8.56e-151	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
PICBCKBE_00910	2.3e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PICBCKBE_00911	1.08e-210	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PICBCKBE_00912	4.51e-111	yhjR	-	-	S	-	-	-	Rubrerythrin
PICBCKBE_00913	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
PICBCKBE_00914	6.11e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
PICBCKBE_00915	9.08e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PICBCKBE_00916	2.57e-222	yhbB	-	-	S	-	-	-	Putative amidase domain
PICBCKBE_00917	6.6e-115	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PICBCKBE_00918	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
PICBCKBE_00919	3.3e-282	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
PICBCKBE_00921	1.74e-135	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PICBCKBE_00922	3.14e-229	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
PICBCKBE_00923	5.31e-149	ykaA	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
PICBCKBE_00924	5.77e-118	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
PICBCKBE_00925	1.43e-110	bdbA	-	-	CO	-	-	-	Thioredoxin
PICBCKBE_00926	8.01e-97	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
PICBCKBE_00927	4.17e-173	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PICBCKBE_00928	8.08e-234	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
PICBCKBE_00929	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
PICBCKBE_00931	7.12e-61	yhdB	-	-	S	-	-	-	YhdB-like protein
PICBCKBE_00932	5.29e-238	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
PICBCKBE_00933	2.4e-168	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
PICBCKBE_00934	4.48e-206	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PICBCKBE_00935	7.38e-225	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PICBCKBE_00936	1.78e-241	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_00937	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PICBCKBE_00938	1.01e-228	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PICBCKBE_00939	1.79e-242	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_00941	2.54e-112	nhaX	-	-	T	-	-	-	Universal stress protein
PICBCKBE_00942	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PICBCKBE_00943	2.73e-209	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00944	1.64e-25	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00945	2.5e-25	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00947	1.33e-292	-	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
PICBCKBE_00949	4.69e-43	-	-	-	-	-	-	-	-
PICBCKBE_00950	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
PICBCKBE_00952	1.58e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PICBCKBE_00953	1.09e-05	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
PICBCKBE_00955	2.04e-309	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PICBCKBE_00956	6.4e-54	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PICBCKBE_00957	1.2e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PICBCKBE_00958	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PICBCKBE_00959	5.06e-280	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PICBCKBE_00960	3.47e-166	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PICBCKBE_00961	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
PICBCKBE_00962	1.74e-308	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PICBCKBE_00963	5.66e-66	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_00964	2.27e-251	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_00965	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
PICBCKBE_00966	1.76e-182	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
PICBCKBE_00967	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PICBCKBE_00968	1.98e-105	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PICBCKBE_00970	2.52e-210	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_00971	3.19e-243	crtQ	-	-	M	ko:K10211	ko00906,map00906	ko00000,ko00001,ko01000	Glycosyl transferase family 21
PICBCKBE_00972	2.72e-129	-	-	-	-	-	-	-	-
PICBCKBE_00973	1.57e-128	-	-	-	-	-	-	-	-
PICBCKBE_00974	1.31e-51	-	-	-	D	-	-	-	nuclear chromosome segregation
PICBCKBE_00976	3.94e-49	XK26_06125	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
PICBCKBE_00977	5.88e-277	-	-	-	O	-	-	-	Peptidase S53
PICBCKBE_00979	2.27e-10	-	-	-	L	-	-	-	Mu transposase, C-terminal
PICBCKBE_00980	3.01e-303	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_00981	3.63e-10	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
PICBCKBE_00982	2.29e-177	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
PICBCKBE_00983	5.43e-156	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
PICBCKBE_00984	1.04e-244	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PICBCKBE_00985	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
PICBCKBE_00986	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
PICBCKBE_00987	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
PICBCKBE_00988	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PICBCKBE_00989	1.01e-181	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_00990	6.51e-214	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PICBCKBE_00991	1.82e-228	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
PICBCKBE_00992	2.26e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PICBCKBE_00993	0.0	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	cell adhesion
PICBCKBE_00994	0.0	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
PICBCKBE_00995	7.84e-286	ykoN	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PICBCKBE_00996	1.34e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PICBCKBE_00997	1.41e-114	-	-	-	S	-	-	-	Putative zinc-finger
PICBCKBE_00998	2.15e-184	-	-	-	-	-	-	-	-
PICBCKBE_00999	6.85e-313	ugtP5	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Monogalactosyldiacylglycerol (MGDG) synthase
PICBCKBE_01000	3.17e-184	-	-	-	G	-	-	-	Polysaccharide deacetylase
PICBCKBE_01001	4.97e-138	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
PICBCKBE_01002	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PICBCKBE_01003	5.83e-251	M1-600	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
PICBCKBE_01005	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PICBCKBE_01006	2.88e-10	-	-	-	-	-	-	-	-
PICBCKBE_01007	0.0	cls2	-	-	I	-	-	-	PLD-like domain
PICBCKBE_01008	6.96e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
PICBCKBE_01009	1.29e-261	-	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PICBCKBE_01010	3.32e-74	yusN	-	-	M	-	-	-	Coat F domain
PICBCKBE_01011	8.24e-56	-	-	-	-	-	-	-	-
PICBCKBE_01012	3.69e-21	-	-	-	S	-	-	-	YuzL-like protein
PICBCKBE_01013	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
PICBCKBE_01014	5.89e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
PICBCKBE_01015	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
PICBCKBE_01016	3.13e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PICBCKBE_01017	4.68e-82	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PICBCKBE_01018	6.34e-66	yusE	-	-	CO	-	-	-	Thioredoxin
PICBCKBE_01020	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PICBCKBE_01021	5e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
PICBCKBE_01022	1.58e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PICBCKBE_01023	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
PICBCKBE_01024	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
PICBCKBE_01025	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PICBCKBE_01026	6.33e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
PICBCKBE_01027	8.63e-165	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
PICBCKBE_01028	4.98e-253	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
PICBCKBE_01029	5.82e-221	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PICBCKBE_01030	4.18e-64	yutD	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01031	1.32e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
PICBCKBE_01032	5.87e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PICBCKBE_01033	5.12e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
PICBCKBE_01034	1.55e-256	yutH	-	-	S	-	-	-	Spore coat protein
PICBCKBE_01035	6.83e-50	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
PICBCKBE_01036	3.46e-80	yuzD	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01037	4.8e-83	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
PICBCKBE_01039	9.63e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF5105)
PICBCKBE_01040	4.36e-100	-	-	-	S	-	-	-	response to antibiotic
PICBCKBE_01041	7.12e-73	-	-	-	S	-	-	-	response to antibiotic
PICBCKBE_01042	1.99e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
PICBCKBE_01043	2.09e-287	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PICBCKBE_01044	5.14e-62	yuiB	-	-	S	-	-	-	Putative membrane protein
PICBCKBE_01045	3.72e-139	yuiC	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01046	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PICBCKBE_01048	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
PICBCKBE_01049	4.87e-280	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
PICBCKBE_01050	5.28e-244	gerKB	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
PICBCKBE_01052	1.38e-82	yuzC	-	-	-	-	-	-	-
PICBCKBE_01053	7.74e-86	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
PICBCKBE_01054	2.03e-258	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_01055	3.62e-160	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_01056	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_01057	3.79e-22	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_01058	3e-23	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
PICBCKBE_01059	3.04e-87	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
PICBCKBE_01060	1.66e-144	ppiA	5.2.1.8	-	O	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PICBCKBE_01061	7.1e-06	-	-	-	-	-	-	-	-
PICBCKBE_01062	5.74e-304	-	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01063	2.52e-202	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
PICBCKBE_01064	3.76e-211	-	-	-	S	-	-	-	reductase
PICBCKBE_01065	1.18e-250	yqjM1	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PICBCKBE_01066	1.5e-40	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PICBCKBE_01067	9.05e-85	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
PICBCKBE_01070	5.46e-113	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
PICBCKBE_01071	1.11e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
PICBCKBE_01072	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PICBCKBE_01073	1.75e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
PICBCKBE_01076	3.08e-213	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	ornithine cyclodeaminase
PICBCKBE_01077	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PICBCKBE_01078	3.54e-277	-	1.5.3.1	-	E	ko:K00303	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
PICBCKBE_01079	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_01080	1.65e-86	solA	1.5.3.1	-	E	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
PICBCKBE_01081	1.72e-116	solA	1.5.3.1	-	E	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
PICBCKBE_01082	4.62e-96	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
PICBCKBE_01083	1e-173	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_01084	1.51e-259	-	-	-	M	-	-	-	Glycosyl transferase family 2
PICBCKBE_01085	7.74e-162	-	-	-	I	-	-	-	Acyl-transferase
PICBCKBE_01086	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PICBCKBE_01087	3.43e-307	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
PICBCKBE_01088	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
PICBCKBE_01089	1.75e-284	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PICBCKBE_01090	3.18e-244	araH	-	-	G	ko:K10544,ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PICBCKBE_01091	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PICBCKBE_01092	1.55e-253	chvE	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PICBCKBE_01093	5.18e-272	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
PICBCKBE_01094	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PICBCKBE_01095	1.19e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PICBCKBE_01096	0.0	araP	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PICBCKBE_01097	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
PICBCKBE_01098	7.75e-94	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PICBCKBE_01099	1.48e-176	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
PICBCKBE_01100	8e-16	-	-	-	-	-	-	-	-
PICBCKBE_01101	6.24e-24	csoR	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01102	3.89e-65	-	-	-	P	-	-	-	Rhodanese domain protein
PICBCKBE_01103	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_01104	3.75e-306	-	-	-	P	-	-	-	Voltage gated chloride channel
PICBCKBE_01105	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_01107	1.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PICBCKBE_01110	4.44e-223	nodB1	-	-	G	-	-	-	deacetylase
PICBCKBE_01112	2.92e-37	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
PICBCKBE_01114	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PICBCKBE_01115	3.42e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
PICBCKBE_01116	3.6e-285	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PICBCKBE_01117	1.46e-97	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PICBCKBE_01118	1.3e-90	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
PICBCKBE_01119	6.72e-245	-	-	-	L	-	-	-	COG3039 Transposase and inactivated derivatives, IS5 family
PICBCKBE_01120	2.96e-72	csoR_2	-	-	S	ko:K21600	-	ko00000,ko03000	protein conserved in bacteria
PICBCKBE_01121	1.19e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
PICBCKBE_01122	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PICBCKBE_01123	2.69e-56	-	-	-	L	-	-	-	Transposase
PICBCKBE_01124	4.43e-26	-	-	-	-	-	-	-	-
PICBCKBE_01126	2.73e-150	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01127	2.56e-122	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01128	3.54e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF1646)
PICBCKBE_01129	1.31e-149	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
PICBCKBE_01130	1.1e-133	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PICBCKBE_01131	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_01132	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_01153	1.25e-211	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
PICBCKBE_01154	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
PICBCKBE_01155	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PICBCKBE_01156	3.41e-189	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PICBCKBE_01157	3.06e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PICBCKBE_01158	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PICBCKBE_01159	7.56e-266	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PICBCKBE_01160	5.75e-33	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
PICBCKBE_01161	3.6e-210	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PICBCKBE_01163	1.27e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PICBCKBE_01164	7.57e-103	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PICBCKBE_01165	2.31e-52	-	-	-	-	-	-	-	-
PICBCKBE_01166	1.64e-108	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
PICBCKBE_01167	1.02e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PICBCKBE_01168	2.91e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PICBCKBE_01169	1.4e-238	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PICBCKBE_01170	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PICBCKBE_01171	4.85e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
PICBCKBE_01172	1.51e-261	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PICBCKBE_01173	1.28e-89	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
PICBCKBE_01174	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PICBCKBE_01175	1.85e-282	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PICBCKBE_01176	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PICBCKBE_01177	1.29e-107	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PICBCKBE_01178	2.16e-197	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
PICBCKBE_01179	7.59e-269	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
PICBCKBE_01180	1.37e-134	ytqB	-	-	J	-	-	-	Putative rRNA methylase
PICBCKBE_01181	4.76e-56	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
PICBCKBE_01182	4.49e-236	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_01183	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PICBCKBE_01186	9.36e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
PICBCKBE_01187	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PICBCKBE_01188	9e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
PICBCKBE_01189	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
PICBCKBE_01190	4.89e-204	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PICBCKBE_01192	4.8e-139	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PICBCKBE_01193	8.11e-196	ytlQ	-	-	-	-	-	-	-
PICBCKBE_01194	2.25e-201	ytmP	-	-	M	-	-	-	Phosphotransferase
PICBCKBE_01195	5.63e-77	ytzH	-	-	S	-	-	-	YtzH-like protein
PICBCKBE_01196	1.29e-170	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PICBCKBE_01198	3.37e-218	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PICBCKBE_01199	2.11e-69	ytzB	-	-	S	-	-	-	small secreted protein
PICBCKBE_01200	2.61e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
PICBCKBE_01201	1.24e-118	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PICBCKBE_01202	6.75e-304	-	-	-	L	-	-	-	Transposase DDE domain group 1
PICBCKBE_01203	3.24e-74	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PICBCKBE_01205	0.0	-	2.7.13.3	-	T	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	Histidine kinase
PICBCKBE_01206	1.06e-198	-	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	chemotaxis
PICBCKBE_01207	2.67e-272	rsbU	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
PICBCKBE_01208	2.45e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
PICBCKBE_01209	3.69e-187	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
PICBCKBE_01210	7.55e-142	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PICBCKBE_01211	9.16e-128	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PICBCKBE_01212	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PICBCKBE_01213	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PICBCKBE_01214	7.74e-84	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PICBCKBE_01215	1.51e-52	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
PICBCKBE_01216	3.79e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PICBCKBE_01217	2.41e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PICBCKBE_01218	9.26e-296	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
PICBCKBE_01219	8.43e-155	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
PICBCKBE_01220	2e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PICBCKBE_01221	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PICBCKBE_01222	1.96e-158	-	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdenum ABC transporter
PICBCKBE_01223	6.28e-133	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
PICBCKBE_01224	1.19e-170	-	3.6.3.29	-	P	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_01225	8.82e-241	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PICBCKBE_01226	1.93e-111	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
PICBCKBE_01227	1.24e-156	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PICBCKBE_01228	1.31e-305	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
PICBCKBE_01229	1.55e-114	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
PICBCKBE_01230	1.16e-102	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
PICBCKBE_01231	1.45e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PICBCKBE_01232	4.1e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PICBCKBE_01233	4.95e-247	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PICBCKBE_01234	4.84e-114	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PICBCKBE_01235	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
PICBCKBE_01236	3.86e-196	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PICBCKBE_01238	2.43e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PICBCKBE_01239	3.04e-313	-	-	-	KT	-	-	-	Transcriptional regulator
PICBCKBE_01240	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
PICBCKBE_01241	3.44e-237	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
PICBCKBE_01242	5.36e-92	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PICBCKBE_01243	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PICBCKBE_01244	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_01245	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
PICBCKBE_01246	5.64e-112	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PICBCKBE_01247	1.07e-151	yttP	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_01248	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PICBCKBE_01249	4.8e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PICBCKBE_01250	9.22e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PICBCKBE_01251	7.27e-38	B4168_3115	-	-	S	ko:K06419	-	ko00000	spore protein
PICBCKBE_01252	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PICBCKBE_01253	1.03e-237	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
PICBCKBE_01254	1.63e-116	yteJ	-	-	S	-	-	-	RDD family
PICBCKBE_01255	3.02e-152	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
PICBCKBE_01256	1.39e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
PICBCKBE_01257	4.75e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PICBCKBE_01258	2.71e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
PICBCKBE_01259	1.45e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PICBCKBE_01260	6.19e-201	-	-	-	S	-	-	-	EcsC protein family
PICBCKBE_01261	4.68e-104	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
PICBCKBE_01262	7.47e-259	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
PICBCKBE_01263	1.92e-262	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
PICBCKBE_01264	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
PICBCKBE_01265	1.36e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
PICBCKBE_01266	5.22e-56	ytpI	-	-	S	-	-	-	YtpI-like protein
PICBCKBE_01267	3.52e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
PICBCKBE_01268	7.28e-117	ytrI	-	-	-	-	-	-	-
PICBCKBE_01269	4.78e-69	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
PICBCKBE_01270	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PICBCKBE_01271	1.8e-288	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
PICBCKBE_01272	2.01e-209	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PICBCKBE_01273	8.01e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PICBCKBE_01274	5.39e-224	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PICBCKBE_01275	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PICBCKBE_01276	2.16e-231	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
PICBCKBE_01277	1.05e-96	-	-	-	S	-	-	-	Membrane
PICBCKBE_01278	1.08e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
PICBCKBE_01279	2.57e-311	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
PICBCKBE_01280	1.59e-216	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
PICBCKBE_01281	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PICBCKBE_01282	6.69e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PICBCKBE_01283	5.02e-141	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PICBCKBE_01284	1.91e-130	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PICBCKBE_01285	1.66e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PICBCKBE_01286	4.02e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PICBCKBE_01287	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
PICBCKBE_01288	3.15e-229	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PICBCKBE_01289	1.15e-197	ytxC	-	-	S	-	-	-	YtxC-like family
PICBCKBE_01290	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PICBCKBE_01291	8.32e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
PICBCKBE_01292	8.37e-145	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PICBCKBE_01293	4.3e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PICBCKBE_01294	3.16e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PICBCKBE_01296	1.36e-101	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PICBCKBE_01297	0.0	-	-	-	M	-	-	-	O-Antigen ligase
PICBCKBE_01298	2.28e-122	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PICBCKBE_01299	5.27e-235	-	-	-	C	-	-	-	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PICBCKBE_01300	1.26e-214	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PICBCKBE_01301	9.34e-130	-	-	-	S	ko:K19784	-	ko00000	NAD(P)H-dependent FMN reductase
PICBCKBE_01302	1.82e-226	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PICBCKBE_01303	2.72e-163	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PICBCKBE_01304	1.1e-15	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PICBCKBE_01305	1.01e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_01306	2.03e-154	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PICBCKBE_01307	7.63e-74	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
PICBCKBE_01308	8.95e-65	-	-	-	-	-	-	-	-
PICBCKBE_01309	2.18e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4405)
PICBCKBE_01310	7.52e-293	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
PICBCKBE_01311	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_01312	7.18e-76	-	-	-	-	-	-	-	-
PICBCKBE_01313	2.36e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
PICBCKBE_01314	9.02e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PICBCKBE_01317	8.65e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PICBCKBE_01318	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PICBCKBE_01319	9.21e-216	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PICBCKBE_01320	3.12e-61	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PICBCKBE_01321	1.05e-114	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
PICBCKBE_01322	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
PICBCKBE_01323	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PICBCKBE_01324	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_01325	5.75e-135	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_01326	3.14e-180	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
PICBCKBE_01327	1.13e-173	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
PICBCKBE_01328	4.08e-222	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
PICBCKBE_01329	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01330	9.61e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PICBCKBE_01331	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PICBCKBE_01332	5.94e-282	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PICBCKBE_01333	4.17e-107	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PICBCKBE_01334	5.93e-135	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
PICBCKBE_01335	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
PICBCKBE_01336	8.45e-193	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
PICBCKBE_01337	1.33e-114	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
PICBCKBE_01338	3.8e-43	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_01340	2.11e-249	-	-	-	S	-	-	-	Predicted membrane protein (DUF2157)
PICBCKBE_01341	2.51e-120	-	-	-	S	-	-	-	GDYXXLXY protein
PICBCKBE_01342	9.88e-105	ysmB	-	-	K	-	-	-	transcriptional
PICBCKBE_01343	4.15e-191	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PICBCKBE_01344	2.16e-43	yraG	-	-	S	ko:K06440	-	ko00000	Spore Coat Protein
PICBCKBE_01345	5.35e-81	yraF	-	-	M	-	-	-	Spore coat protein
PICBCKBE_01346	1.51e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PICBCKBE_01347	3.57e-62	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
PICBCKBE_01348	4.29e-32	yraE	-	-	-	ko:K06440	-	ko00000	-
PICBCKBE_01349	1.59e-245	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
PICBCKBE_01350	3.72e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PICBCKBE_01351	4.92e-120	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PICBCKBE_01354	2.17e-62	-	-	-	-	-	-	-	-
PICBCKBE_01355	1.36e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
PICBCKBE_01356	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_01357	1.51e-235	-	-	-	S	-	-	-	chaperone-mediated protein folding
PICBCKBE_01358	8.15e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PICBCKBE_01359	1.2e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PICBCKBE_01360	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
PICBCKBE_01361	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PICBCKBE_01362	8.22e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PICBCKBE_01363	3.11e-116	ysxD	-	-	-	-	-	-	-
PICBCKBE_01364	1.09e-308	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PICBCKBE_01365	8.69e-191	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
PICBCKBE_01366	1.26e-217	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PICBCKBE_01367	9.06e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
PICBCKBE_01368	6.18e-237	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
PICBCKBE_01369	9.69e-317	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
PICBCKBE_01370	4.72e-304	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
PICBCKBE_01371	1.21e-287	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PICBCKBE_01372	3.74e-36	-	-	-	-	-	-	-	-
PICBCKBE_01373	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PICBCKBE_01374	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PICBCKBE_01375	9.73e-06	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
PICBCKBE_01376	1.2e-111	-	-	-	-	-	-	-	-
PICBCKBE_01377	0.0	-	-	-	NU	-	-	-	Pilus assembly protein PilX
PICBCKBE_01378	1.17e-294	-	-	-	-	-	-	-	-
PICBCKBE_01379	1.67e-163	-	-	-	S	-	-	-	PRC-barrel domain
PICBCKBE_01380	9.5e-294	-	-	-	V	-	-	-	G5
PICBCKBE_01381	0.0	pilB	-	-	NU	ko:K02243,ko:K02652	-	ko00000,ko00002,ko02035,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PICBCKBE_01382	2.77e-248	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	twitching motility protein
PICBCKBE_01383	9.56e-268	pilC	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	type II secretion system
PICBCKBE_01384	6.08e-82	-	-	-	NU	ko:K02650	ko02020,map02020	ko00000,ko00001,ko02035,ko02044	Prokaryotic N-terminal methylation motif
PICBCKBE_01385	4.07e-246	-	-	-	NU	ko:K02662,ko:K02663	-	ko00000,ko02035,ko02044	COG4972 Tfp pilus assembly protein, ATPase PilM
PICBCKBE_01386	1.65e-118	-	-	-	NU	ko:K02663	-	ko00000,ko02035,ko02044	PFAM Fimbrial assembly family protein
PICBCKBE_01387	1.84e-147	-	-	-	-	ko:K02664	-	ko00000,ko02035,ko02044	-
PICBCKBE_01388	1.24e-184	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PICBCKBE_01389	7.3e-221	spoIIB	-	-	-	ko:K06380	-	ko00000	-
PICBCKBE_01390	4.65e-158	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
PICBCKBE_01391	1.34e-233	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
PICBCKBE_01392	9.97e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PICBCKBE_01393	2.23e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
PICBCKBE_01394	1.38e-156	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PICBCKBE_01395	9e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PICBCKBE_01396	1.97e-175	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
PICBCKBE_01397	9.19e-209	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
PICBCKBE_01398	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
PICBCKBE_01399	2.58e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PICBCKBE_01400	6.88e-71	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
PICBCKBE_01401	5.39e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PICBCKBE_01402	3.43e-128	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
PICBCKBE_01403	1.83e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PICBCKBE_01404	6.2e-98	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
PICBCKBE_01405	9.91e-205	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
PICBCKBE_01406	7.65e-125	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
PICBCKBE_01407	2.03e-227	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
PICBCKBE_01408	3.2e-242	-	-	-	M	-	-	-	choline kinase involved in LPS biosynthesis
PICBCKBE_01409	1.09e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
PICBCKBE_01410	2.52e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PICBCKBE_01411	4.16e-234	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PICBCKBE_01412	4.52e-37	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
PICBCKBE_01413	1.42e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PICBCKBE_01414	4.88e-284	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PICBCKBE_01415	7.67e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
PICBCKBE_01416	2.67e-83	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
PICBCKBE_01417	4.76e-137	yrbG	-	-	S	-	-	-	membrane
PICBCKBE_01418	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PICBCKBE_01419	6.7e-72	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
PICBCKBE_01420	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PICBCKBE_01421	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01422	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PICBCKBE_01423	1.2e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PICBCKBE_01424	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PICBCKBE_01425	2.76e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PICBCKBE_01426	5.15e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PICBCKBE_01427	3.83e-147	emrA	-	-	V	-	-	-	Barrel-sandwich domain of CusB or HlyD membrane-fusion
PICBCKBE_01428	0.0	yhcA5	-	-	EGP	-	-	-	the major facilitator superfamily
PICBCKBE_01429	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
PICBCKBE_01431	9.73e-317	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PICBCKBE_01432	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PICBCKBE_01434	1e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
PICBCKBE_01435	3.52e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PICBCKBE_01436	1.24e-298	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PICBCKBE_01437	1.28e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
PICBCKBE_01438	3.63e-103	-	-	-	-	-	-	-	-
PICBCKBE_01439	1.24e-94	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_01440	2.1e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PICBCKBE_01441	4.32e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PICBCKBE_01442	4.88e-162	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
PICBCKBE_01443	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PICBCKBE_01445	1.52e-79	pdh	1.4.1.20	-	E	ko:K00270	ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PICBCKBE_01446	2.49e-09	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
PICBCKBE_01447	3.71e-76	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
PICBCKBE_01448	1.07e-87	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
PICBCKBE_01449	3.5e-40	yrzR	-	-	-	-	-	-	-
PICBCKBE_01451	8.49e-245	yrrI	-	-	S	-	-	-	AI-2E family transporter
PICBCKBE_01452	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PICBCKBE_01453	2.76e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PICBCKBE_01454	7.49e-91	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PICBCKBE_01455	9.07e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PICBCKBE_01456	6.42e-262	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PICBCKBE_01457	9.09e-149	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
PICBCKBE_01458	3.05e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PICBCKBE_01459	7.42e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PICBCKBE_01460	2.18e-99	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
PICBCKBE_01461	2.82e-40	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
PICBCKBE_01462	7.42e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PICBCKBE_01463	2.49e-11	-	-	-	S	-	-	-	YrhC-like protein
PICBCKBE_01465	3.96e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
PICBCKBE_01466	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
PICBCKBE_01468	3.64e-162	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_01469	3.27e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PICBCKBE_01470	7.73e-22	sda	-	-	S	ko:K06371	-	ko00000	Sporulation inhibitor A
PICBCKBE_01471	9.03e-203	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
PICBCKBE_01472	2.98e-152	-	-	-	S	-	-	-	VIT family
PICBCKBE_01473	3.46e-95	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PICBCKBE_01474	4.78e-79	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PICBCKBE_01475	1.54e-82	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PICBCKBE_01476	1.19e-137	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PICBCKBE_01478	8.83e-123	stoA	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PICBCKBE_01479	2.05e-42	-	-	-	S	ko:K08982	-	ko00000	Short C-terminal domain
PICBCKBE_01480	1.32e-92	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PICBCKBE_01481	3.13e-287	mco	-	-	Q	-	-	-	multicopper oxidases
PICBCKBE_01482	4.05e-246	ysfB	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
PICBCKBE_01483	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
PICBCKBE_01484	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
PICBCKBE_01485	1.11e-122	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
PICBCKBE_01486	2.28e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PICBCKBE_01487	3.2e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PICBCKBE_01488	2.57e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
PICBCKBE_01489	2.28e-137	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PICBCKBE_01490	9.63e-130	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
PICBCKBE_01491	1.02e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PICBCKBE_01492	3.18e-189	-	-	-	S	-	-	-	Methyltransferase domain
PICBCKBE_01493	1.62e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PICBCKBE_01494	2.72e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
PICBCKBE_01495	2.64e-146	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	COG2131 Deoxycytidylate deaminase
PICBCKBE_01496	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PICBCKBE_01497	1.18e-11	-	-	-	S	-	-	-	YqzM-like protein
PICBCKBE_01498	4.52e-238	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PICBCKBE_01499	3.34e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PICBCKBE_01500	1.19e-257	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PICBCKBE_01501	1.12e-286	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
PICBCKBE_01502	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PICBCKBE_01503	9.03e-279	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
PICBCKBE_01504	1.59e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PICBCKBE_01505	3.09e-123	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PICBCKBE_01506	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PICBCKBE_01507	7.38e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PICBCKBE_01508	1.32e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
PICBCKBE_01509	1.14e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PICBCKBE_01510	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
PICBCKBE_01511	3.37e-200	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
PICBCKBE_01512	9.76e-64	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PICBCKBE_01513	3.56e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PICBCKBE_01514	1.07e-93	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
PICBCKBE_01515	1.1e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
PICBCKBE_01516	5.57e-290	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
PICBCKBE_01517	4.09e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
PICBCKBE_01518	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
PICBCKBE_01519	8.37e-108	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PICBCKBE_01520	6.81e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PICBCKBE_01521	3.22e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PICBCKBE_01522	8.43e-13	-	-	-	S	-	-	-	YqzL-like protein
PICBCKBE_01523	1.76e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PICBCKBE_01524	4.15e-145	ccpN	-	-	K	-	-	-	CBS domain
PICBCKBE_01525	3.84e-190	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PICBCKBE_01526	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PICBCKBE_01527	4.85e-258	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PICBCKBE_01528	1.01e-112	-	-	-	-	-	-	-	-
PICBCKBE_01529	1.79e-84	cccA	-	-	C	ko:K13300	-	ko00000	Cytochrome C oxidase, cbb3-type, subunit III
PICBCKBE_01530	4.46e-148	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PICBCKBE_01531	2.45e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PICBCKBE_01532	2.81e-231	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PICBCKBE_01533	1.66e-09	yqfQ	-	-	S	-	-	-	YqfQ-like protein
PICBCKBE_01535	7.05e-306	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PICBCKBE_01536	2.19e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PICBCKBE_01537	3.61e-221	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
PICBCKBE_01538	1.94e-27	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
PICBCKBE_01539	5.46e-183	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PICBCKBE_01540	5.71e-181	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PICBCKBE_01541	1.33e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
PICBCKBE_01542	1.48e-146	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
PICBCKBE_01543	1.11e-259	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PICBCKBE_01544	4.46e-72	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
PICBCKBE_01545	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
PICBCKBE_01546	5.85e-275	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
PICBCKBE_01547	0.0	pbpA	-	-	M	ko:K21465	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
PICBCKBE_01548	1.33e-70	yqzD	-	-	-	-	-	-	-
PICBCKBE_01549	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PICBCKBE_01551	7.01e-267	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
PICBCKBE_01552	1.93e-39	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01553	5.87e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PICBCKBE_01554	1.57e-30	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
PICBCKBE_01555	2.01e-159	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
PICBCKBE_01556	1.31e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
PICBCKBE_01557	1.29e-168	-	-	-	K	-	-	-	Helix-turn-helix domain
PICBCKBE_01558	8.22e-269	comGA	-	-	NU	ko:K02243,ko:K02652	-	ko00000,ko00002,ko02035,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PICBCKBE_01559	3.12e-223	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
PICBCKBE_01560	1.67e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
PICBCKBE_01561	2.1e-99	comGD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	COG2165 Type II secretory pathway, pseudopilin PulG
PICBCKBE_01563	1.27e-109	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	COG4940 Competence protein ComGF
PICBCKBE_01564	5.35e-81	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
PICBCKBE_01565	2.04e-129	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PICBCKBE_01566	3.69e-14	yqzE	-	-	S	-	-	-	YqzE-like protein
PICBCKBE_01567	5.31e-200	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
PICBCKBE_01568	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
PICBCKBE_01569	1.95e-271	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
PICBCKBE_01570	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PICBCKBE_01571	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PICBCKBE_01572	3.28e-87	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
PICBCKBE_01573	2.74e-205	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PICBCKBE_01574	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
PICBCKBE_01575	5.65e-130	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
PICBCKBE_01576	7.88e-34	paaG	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Enoyl-CoA hydratase
PICBCKBE_01577	0.0	-	1.2.1.3, 1.2.1.8	-	C	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PICBCKBE_01578	2.32e-196	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
PICBCKBE_01579	1.06e-279	pcaF	2.3.1.174, 2.3.1.223	-	I	ko:K02615	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the thiolase family
PICBCKBE_01580	2.68e-226	paaX	-	-	K	ko:K02616	-	ko00000,ko03000	PaaX-like protein
PICBCKBE_01581	1.07e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PICBCKBE_01582	1.26e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
PICBCKBE_01583	9.04e-18	yqhP	-	-	-	-	-	-	-
PICBCKBE_01584	2.32e-207	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
PICBCKBE_01585	2.13e-111	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
PICBCKBE_01586	1.78e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
PICBCKBE_01587	6.2e-242	yqhT	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
PICBCKBE_01588	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PICBCKBE_01589	1.32e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
PICBCKBE_01590	2.42e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
PICBCKBE_01591	3.6e-38	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
PICBCKBE_01592	2.48e-78	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
PICBCKBE_01593	2.12e-258	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
PICBCKBE_01594	2.58e-139	spoIIIAF	-	-	S	ko:K06395	-	ko00000	stage III sporulation protein AF
PICBCKBE_01595	1.55e-142	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
PICBCKBE_01596	1.12e-110	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
PICBCKBE_01597	2.67e-106	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PICBCKBE_01598	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PICBCKBE_01599	7.54e-90	yqhY	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01600	3.5e-84	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PICBCKBE_01601	3.88e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PICBCKBE_01602	3.18e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PICBCKBE_01603	4.77e-42	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PICBCKBE_01604	1.52e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PICBCKBE_01605	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PICBCKBE_01606	4.13e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
PICBCKBE_01607	2.26e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PICBCKBE_01608	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PICBCKBE_01609	5.17e-308	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
PICBCKBE_01611	3.14e-182	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PICBCKBE_01612	1.1e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PICBCKBE_01613	1.31e-48	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
PICBCKBE_01614	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
PICBCKBE_01615	1.39e-64	-	-	-	T	-	-	-	transcription factor binding
PICBCKBE_01616	1.53e-265	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PICBCKBE_01617	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PICBCKBE_01618	1.52e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PICBCKBE_01619	8.08e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PICBCKBE_01620	4.55e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PICBCKBE_01621	2.63e-211	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
PICBCKBE_01622	5.17e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
PICBCKBE_01623	1.08e-122	yqjB	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01624	4.82e-171	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01625	1.04e-132	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_01626	6.14e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
PICBCKBE_01627	1.81e-103	-	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
PICBCKBE_01628	7.08e-292	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PICBCKBE_01629	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PICBCKBE_01630	1.32e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PICBCKBE_01631	1.86e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PICBCKBE_01632	3.82e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PICBCKBE_01633	4.05e-306	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PICBCKBE_01634	1.17e-73	yqiX	-	-	S	-	-	-	YolD-like protein
PICBCKBE_01635	1.82e-311	yaaH_2	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
PICBCKBE_01636	2.21e-225	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
PICBCKBE_01637	1.5e-276	yaaN	-	-	P	-	-	-	Belongs to the TelA family
PICBCKBE_01638	8.3e-142	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PICBCKBE_01640	1.86e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF3886)
PICBCKBE_01641	1.52e-210	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
PICBCKBE_01642	4.88e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
PICBCKBE_01643	1.6e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
PICBCKBE_01644	9.57e-288	yqxK	-	-	L	-	-	-	DNA helicase
PICBCKBE_01645	1.09e-136	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PICBCKBE_01646	3.96e-109	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PICBCKBE_01647	2.06e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
PICBCKBE_01648	8.54e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
PICBCKBE_01649	3.01e-273	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PICBCKBE_01650	4.34e-75	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
PICBCKBE_01651	8.55e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PICBCKBE_01652	8.59e-171	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_01653	4.9e-145	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
PICBCKBE_01654	1.75e-95	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
PICBCKBE_01655	2.47e-137	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
PICBCKBE_01656	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
PICBCKBE_01657	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PICBCKBE_01658	1.28e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PICBCKBE_01659	1.13e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PICBCKBE_01660	5.61e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PICBCKBE_01661	7.85e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PICBCKBE_01662	1.37e-271	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PICBCKBE_01663	1.94e-124	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
PICBCKBE_01664	1.14e-113	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
PICBCKBE_01665	3.11e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PICBCKBE_01666	2.14e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PICBCKBE_01667	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
PICBCKBE_01668	2.11e-292	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PICBCKBE_01669	2.06e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_01670	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_01671	1.57e-175	-	-	-	M	-	-	-	COG0739 Membrane proteins related to metalloendopeptidases
PICBCKBE_01672	1.58e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PICBCKBE_01673	1.69e-54	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
PICBCKBE_01674	2.71e-259	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
PICBCKBE_01675	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
PICBCKBE_01676	6e-130	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
PICBCKBE_01678	1.26e-105	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
PICBCKBE_01679	2.19e-135	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
PICBCKBE_01680	1.24e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
PICBCKBE_01681	8.41e-54	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
PICBCKBE_01682	5.66e-184	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
PICBCKBE_01683	7.27e-145	-	-	-	NOT	ko:K16511	-	ko00000	Negative regulator of genetic competence (MecA)
PICBCKBE_01684	6.55e-310	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PICBCKBE_01685	1.77e-237	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
PICBCKBE_01686	9.82e-164	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
PICBCKBE_01687	4.17e-193	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
PICBCKBE_01688	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
PICBCKBE_01689	1.84e-153	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
PICBCKBE_01690	2.98e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PICBCKBE_01691	2.71e-260	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PICBCKBE_01692	9.95e-21	-	-	-	S	-	-	-	YpzI-like protein
PICBCKBE_01693	2.35e-13	yphA	-	-	-	-	-	-	-
PICBCKBE_01694	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PICBCKBE_01695	2.27e-245	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PICBCKBE_01696	7.83e-13	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
PICBCKBE_01697	1.7e-175	yphF	-	-	-	-	-	-	-
PICBCKBE_01698	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PICBCKBE_01699	1.54e-56	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PICBCKBE_01700	1.85e-44	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PICBCKBE_01701	1.05e-184	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PICBCKBE_01702	2.4e-168	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PICBCKBE_01703	5.62e-226	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PICBCKBE_01704	8.2e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PICBCKBE_01705	4.49e-187	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
PICBCKBE_01706	1.7e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PICBCKBE_01707	1.46e-264	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PICBCKBE_01708	6.31e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PICBCKBE_01709	1.79e-267	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PICBCKBE_01710	3.72e-261	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
PICBCKBE_01711	4.07e-305	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PICBCKBE_01712	2.54e-305	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
PICBCKBE_01713	3.68e-130	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
PICBCKBE_01714	1.46e-111	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
PICBCKBE_01715	5.32e-129	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
PICBCKBE_01716	2.94e-164	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
PICBCKBE_01717	1.52e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
PICBCKBE_01718	2.97e-142	ypjA	-	-	S	-	-	-	membrane
PICBCKBE_01719	5.43e-184	ypjB	-	-	S	-	-	-	sporulation protein
PICBCKBE_01720	3.83e-137	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
PICBCKBE_01721	1.88e-106	queT	-	-	S	-	-	-	QueT transporter
PICBCKBE_01722	1.65e-206	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PICBCKBE_01723	3.2e-76	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
PICBCKBE_01724	1.15e-191	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PICBCKBE_01725	3.29e-171	ypjG	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
PICBCKBE_01726	9.14e-283	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
PICBCKBE_01727	4.76e-288	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PICBCKBE_01728	6.35e-230	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PICBCKBE_01729	8.05e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PICBCKBE_01730	4.34e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PICBCKBE_01731	8.4e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PICBCKBE_01732	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PICBCKBE_01733	6.71e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01734	7.45e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PICBCKBE_01735	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
PICBCKBE_01736	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_01737	5.25e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
PICBCKBE_01738	1.07e-159	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PICBCKBE_01739	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PICBCKBE_01740	1.65e-145	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PICBCKBE_01743	1.13e-81	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
PICBCKBE_01744	3.92e-110	yppG	-	-	S	-	-	-	YppG-like protein
PICBCKBE_01745	3.62e-100	hspc4-1	-	-	O	-	-	-	Belongs to the small heat shock protein (HSP20) family
PICBCKBE_01746	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PICBCKBE_01747	0.0	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
PICBCKBE_01748	2.98e-62	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
PICBCKBE_01749	1.56e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PICBCKBE_01750	2.07e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PICBCKBE_01751	3.3e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PICBCKBE_01752	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PICBCKBE_01753	2.74e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PICBCKBE_01754	5.86e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
PICBCKBE_01755	4.41e-169	-	-	-	O	-	-	-	prohibitin homologues
PICBCKBE_01756	3.54e-47	-	-	-	-	-	-	-	-
PICBCKBE_01757	0.0	ypbR	-	-	S	-	-	-	Dynamin family
PICBCKBE_01758	1.01e-86	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
PICBCKBE_01759	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PICBCKBE_01760	1.94e-173	-	-	-	L	-	-	-	Arm DNA-binding domain
PICBCKBE_01761	4.96e-58	-	-	-	E	-	-	-	IrrE N-terminal-like domain
PICBCKBE_01763	0.0	-	-	-	L	-	-	-	Type III restriction protein, res subunit
PICBCKBE_01764	5.34e-52	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	RNase_H superfamily
PICBCKBE_01765	5.8e-94	-	-	-	L	-	-	-	PFAM BRCA1 C Terminus (BRCT) domain
PICBCKBE_01766	5.48e-37	-	-	-	K	-	-	-	transcriptional
PICBCKBE_01767	2.28e-05	-	-	-	K	-	-	-	XRE family transcriptional regulator
PICBCKBE_01768	2.19e-74	-	-	-	-	-	-	-	-
PICBCKBE_01769	1.79e-39	-	-	-	-	-	-	-	-
PICBCKBE_01774	1.78e-102	-	-	-	L	-	-	-	Replication initiation and membrane attachment
PICBCKBE_01775	2.03e-48	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PICBCKBE_01781	2.76e-70	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
PICBCKBE_01782	1.72e-68	-	-	-	M	-	-	-	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PICBCKBE_01783	1.03e-90	-	-	-	L	-	-	-	Phage integrase family
PICBCKBE_01784	1.37e-24	-	-	-	-	-	-	-	-
PICBCKBE_01785	3.92e-23	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH nucleases
PICBCKBE_01786	1.32e-28	-	-	-	-	-	-	-	-
PICBCKBE_01787	1.98e-315	-	-	-	S	-	-	-	Terminase
PICBCKBE_01788	1.48e-167	-	-	-	S	-	-	-	TIGRFAM phage portal protein, HK97 family
PICBCKBE_01789	2.16e-87	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
PICBCKBE_01790	1.98e-107	-	-	-	S	-	-	-	Phage capsid family
PICBCKBE_01791	4.32e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PICBCKBE_01792	1.05e-28	-	-	-	S	-	-	-	Phage head-tail joining protein
PICBCKBE_01793	7.11e-16	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PICBCKBE_01795	4.55e-36	-	-	-	S	-	-	-	Phage tail tube protein
PICBCKBE_01797	9.9e-265	-	-	-	D	-	-	-	Phage tail tape measure protein
PICBCKBE_01798	4.79e-42	-	-	-	S	-	-	-	Phage tail protein
PICBCKBE_01799	1.07e-87	-	-	-	S	-	-	-	Prophage endopeptidase tail
PICBCKBE_01800	4.83e-115	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PICBCKBE_01803	5.81e-15	-	-	-	-	-	-	-	-
PICBCKBE_01804	8.5e-19	-	-	-	-	-	-	-	-
PICBCKBE_01805	1.88e-19	-	-	-	S	-	-	-	Haemolysin XhlA
PICBCKBE_01806	5.75e-31	-	-	-	S	-	-	-	SPP1 phage holin
PICBCKBE_01807	1.26e-75	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	hmm pf01520
PICBCKBE_01809	3.86e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PICBCKBE_01810	1.94e-76	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PICBCKBE_01811	3.69e-150	yneB	-	-	L	-	-	-	resolvase
PICBCKBE_01812	5.7e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
PICBCKBE_01813	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PICBCKBE_01814	2.67e-101	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
PICBCKBE_01815	1.25e-38	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
PICBCKBE_01816	1.01e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
PICBCKBE_01817	1.96e-77	yneI	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
PICBCKBE_01818	1.09e-100	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
PICBCKBE_01819	9.17e-100	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
PICBCKBE_01820	1.36e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PICBCKBE_01821	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
PICBCKBE_01822	2.2e-224	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
PICBCKBE_01824	2.54e-42	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
PICBCKBE_01825	1.02e-112	-	-	-	-	-	-	-	-
PICBCKBE_01826	2.42e-197	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
PICBCKBE_01827	3.71e-105	-	-	-	-	-	-	-	-
PICBCKBE_01829	6.35e-256	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PICBCKBE_01830	1.11e-299	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PICBCKBE_01831	8.33e-183	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
PICBCKBE_01832	4.74e-287	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
PICBCKBE_01833	1.12e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PICBCKBE_01834	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
PICBCKBE_01835	1.89e-227	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PICBCKBE_01836	2.21e-295	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PICBCKBE_01837	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PICBCKBE_01838	4.4e-290	-	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PICBCKBE_01839	1.97e-63	-	-	-	P	ko:K04758	-	ko00000,ko02000	COG1918 Fe2 transport system protein A
PICBCKBE_01840	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PICBCKBE_01841	3.77e-32	-	-	-	S	-	-	-	Virus attachment protein p12 family
PICBCKBE_01842	3.93e-140	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PICBCKBE_01843	2.53e-67	tnrA	-	-	K	-	-	-	transcriptional
PICBCKBE_01844	2.55e-166	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
PICBCKBE_01845	8.07e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PICBCKBE_01846	4.44e-295	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
PICBCKBE_01847	2.59e-277	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PICBCKBE_01848	1.52e-93	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PICBCKBE_01849	4.84e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PICBCKBE_01850	7.11e-293	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PICBCKBE_01851	4.41e-247	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
PICBCKBE_01852	3.42e-175	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
PICBCKBE_01853	4.42e-249	selD	2.7.9.3	-	E	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
PICBCKBE_01854	1.97e-256	selU	-	-	S	ko:K06917	-	ko00000,ko01000,ko03016	tRNA 2-selenouridine synthase
PICBCKBE_01856	3.69e-282	dld	1.1.2.4	-	C	ko:K00102	ko00620,map00620	ko00000,ko00001,ko01000	Glycolate oxidase subunit
PICBCKBE_01857	1.58e-34	dld	1.1.2.4	-	C	ko:K00102	ko00620,map00620	ko00000,ko00001,ko01000	Glycolate oxidase subunit
PICBCKBE_01858	1.29e-198	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_01859	1.59e-104	-	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
PICBCKBE_01860	3.34e-92	-	-	-	I	-	-	-	MaoC like domain
PICBCKBE_01861	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PICBCKBE_01862	5.09e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
PICBCKBE_01863	1.52e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1189)
PICBCKBE_01864	6.74e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
PICBCKBE_01865	1.87e-74	-	-	-	-	-	-	-	-
PICBCKBE_01866	6.27e-219	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_01867	3.76e-217	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PICBCKBE_01868	2.41e-106	-	-	-	V	-	-	-	VanZ like family
PICBCKBE_01869	1.03e-100	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
PICBCKBE_01870	5.39e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PICBCKBE_01871	3.46e-155	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PICBCKBE_01873	3.08e-123	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
PICBCKBE_01874	5.98e-116	-	-	-	Q	-	-	-	protein disulfide oxidoreductase activity
PICBCKBE_01875	1.19e-31	-	-	-	S	-	-	-	YpzG-like protein
PICBCKBE_01877	5.37e-250	-	-	-	G	ko:K07190	ko04020,ko04910,ko04922,map04020,map04910,map04922	ko00000,ko00001	Glycosyl hydrolases family 15
PICBCKBE_01878	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PICBCKBE_01879	2.8e-277	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PICBCKBE_01880	2.39e-254	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
PICBCKBE_01881	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PICBCKBE_01882	5.92e-201	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PICBCKBE_01883	1.99e-189	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PICBCKBE_01884	1.28e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
PICBCKBE_01885	3.14e-275	-	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_01886	5.19e-170	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_01887	1.9e-232	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PICBCKBE_01888	3.38e-104	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PICBCKBE_01889	1.83e-79	-	-	-	-	-	-	-	-
PICBCKBE_01890	2.03e-125	yozB	-	-	S	ko:K08976	-	ko00000	membrane
PICBCKBE_01891	9.84e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PICBCKBE_01892	2.31e-46	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PICBCKBE_01893	2.39e-255	-	-	-	P	-	-	-	FAD-NAD(P)-binding
PICBCKBE_01894	9.28e-46	-	4.1.1.97	-	S	ko:K13485	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	OHCU decarboxylase
PICBCKBE_01895	5.5e-193	-	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
PICBCKBE_01896	4.31e-192	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
PICBCKBE_01897	3.21e-179	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PICBCKBE_01898	9.11e-243	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PICBCKBE_01899	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_01900	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PICBCKBE_01901	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_01902	1.94e-267	-	2.3.1.16, 2.3.1.9	-	I	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PICBCKBE_01903	2.99e-174	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PICBCKBE_01904	1.65e-35	sspH	-	-	S	ko:K06425	-	ko00000	small acid-soluble spore protein
PICBCKBE_01905	2.03e-135	ymdB	-	-	S	-	-	-	Appr-1'-p processing enzyme
PICBCKBE_01907	1.32e-219	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
PICBCKBE_01908	9.27e-75	-	-	-	I	-	-	-	SCP-2 sterol transfer family
PICBCKBE_01909	2.64e-246	-	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PICBCKBE_01910	9.58e-245	-	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	Mechanosensitive ion channel
PICBCKBE_01911	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
PICBCKBE_01912	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PICBCKBE_01913	6.89e-278	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PICBCKBE_01914	2.64e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PICBCKBE_01915	6.98e-241	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PICBCKBE_01916	3.5e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
PICBCKBE_01917	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
PICBCKBE_01918	4.29e-173	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
PICBCKBE_01919	1.31e-141	-	-	-	-	-	-	-	-
PICBCKBE_01920	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PICBCKBE_01921	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PICBCKBE_01922	1.78e-164	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
PICBCKBE_01923	7.71e-183	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
PICBCKBE_01924	1.87e-97	-	-	-	S	ko:K06991	-	ko00000	Glyoxalase bleomycin resistance protein dioxygenase
PICBCKBE_01925	2.94e-237	-	-	-	P	ko:K02051,ko:K15598	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PICBCKBE_01926	6.85e-178	ssuC	-	-	P	ko:K15599	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
PICBCKBE_01927	6.19e-248	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_01928	4.18e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PICBCKBE_01929	1.43e-109	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PICBCKBE_01930	7.8e-153	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PICBCKBE_01932	9.48e-108	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PICBCKBE_01934	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_01937	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_01938	9.17e-39	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PICBCKBE_01939	6.67e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_01940	1.82e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PICBCKBE_01941	1.01e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PICBCKBE_01942	6.89e-170	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PICBCKBE_01943	7.41e-177	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_01944	1.75e-95	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PICBCKBE_01945	6.79e-120	-	-	-	J	-	-	-	acetyltransferase
PICBCKBE_01946	9.87e-111	yvbK	-	-	K	-	-	-	acetyltransferase
PICBCKBE_01947	1.39e-178	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
PICBCKBE_01951	2.17e-205	-	-	-	S	-	-	-	Methyltransferase domain
PICBCKBE_01952	1.44e-218	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
PICBCKBE_01954	5.69e-122	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PICBCKBE_01955	1.75e-133	-	-	-	S	-	-	-	oxidoreductase activity
PICBCKBE_01956	2.79e-254	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PICBCKBE_01960	1.28e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4023)
PICBCKBE_01961	1.07e-90	-	-	-	E	-	-	-	Glyoxalase
PICBCKBE_01962	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
PICBCKBE_01963	6.61e-190	-	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PICBCKBE_01964	7.25e-303	-	-	-	G	-	-	-	Major facilitator superfamily
PICBCKBE_01965	2.72e-191	-	-	-	-	-	-	-	-
PICBCKBE_01966	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PICBCKBE_01967	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PICBCKBE_01968	3.06e-94	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
PICBCKBE_01969	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_01970	2.15e-131	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PICBCKBE_01971	1.65e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PICBCKBE_01972	3.42e-69	yneQ	-	-	-	-	-	-	-
PICBCKBE_01973	1.91e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
PICBCKBE_01974	1.26e-42	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
PICBCKBE_01975	4.72e-28	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
PICBCKBE_01976	1.76e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
PICBCKBE_01977	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PICBCKBE_01978	5.12e-306	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
PICBCKBE_01979	5.79e-52	-	-	-	-	-	-	-	-
PICBCKBE_01980	1.14e-26	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
PICBCKBE_01981	5.89e-33	ydaS	-	-	S	-	-	-	membrane
PICBCKBE_01982	3.9e-149	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
PICBCKBE_01983	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_01984	6.2e-142	-	-	-	M	-	-	-	effector of murein hydrolase
PICBCKBE_01985	4.43e-82	-	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
PICBCKBE_01986	5.78e-57	-	-	-	S	-	-	-	Small, acid-soluble spore proteins, alpha/beta type
PICBCKBE_01987	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PICBCKBE_01988	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PICBCKBE_01989	4.07e-72	-	-	-	S	ko:K13628,ko:K15724	-	ko00000,ko03016	Heme biosynthesis protein HemY
PICBCKBE_01990	1.48e-305	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_01993	1.63e-194	-	-	-	-	-	-	-	-
PICBCKBE_01994	1.24e-258	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
PICBCKBE_01995	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_01996	3.71e-24	-	-	-	-	-	-	-	-
PICBCKBE_01997	5.83e-251	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
PICBCKBE_01998	5.19e-257	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
PICBCKBE_01999	2.69e-88	-	-	-	K	-	-	-	Helix-turn-helix domain
PICBCKBE_02001	9.84e-172	-	-	-	L	-	-	-	PFAM Transposase, Mutator
PICBCKBE_02002	2.33e-68	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PICBCKBE_02003	9.65e-53	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PICBCKBE_02004	8.05e-42	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PICBCKBE_02005	1.07e-34	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacitracin ABC transporter ATP-binding protein
PICBCKBE_02006	1.84e-125	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacitracin ABC transporter ATP-binding protein
PICBCKBE_02007	1.39e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_02008	2.51e-236	bceS	2.7.13.3	-	T	ko:K11629	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
PICBCKBE_02009	1.19e-177	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02010	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
PICBCKBE_02011	1.41e-63	yxiS	-	-	-	-	-	-	-
PICBCKBE_02012	1.05e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF1292)
PICBCKBE_02013	2.78e-222	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
PICBCKBE_02014	1.7e-154	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
PICBCKBE_02015	1.15e-43	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
PICBCKBE_02017	7.2e-130	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PICBCKBE_02018	1.07e-44	-	-	-	S	-	-	-	ATP synthase, subunit b
PICBCKBE_02019	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
PICBCKBE_02020	1.18e-275	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
PICBCKBE_02021	6.02e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
PICBCKBE_02022	1.48e-47	-	-	-	-	-	-	-	-
PICBCKBE_02023	1.62e-174	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
PICBCKBE_02024	1.62e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
PICBCKBE_02025	2.24e-284	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
PICBCKBE_02026	1.01e-222	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
PICBCKBE_02027	5.13e-309	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
PICBCKBE_02028	2.08e-54	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PICBCKBE_02029	1.15e-155	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
PICBCKBE_02030	7.72e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PICBCKBE_02031	3.67e-163	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PICBCKBE_02032	9.55e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PICBCKBE_02033	6.73e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
PICBCKBE_02034	7.21e-299	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PICBCKBE_02035	6.68e-143	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PICBCKBE_02036	9.33e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PICBCKBE_02037	2.7e-91	-	-	-	S	-	-	-	CHY zinc finger
PICBCKBE_02038	3.4e-229	yqxL	-	-	P	-	-	-	Mg2 transporter protein
PICBCKBE_02039	1.99e-146	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
PICBCKBE_02040	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_02041	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PICBCKBE_02042	4.89e-144	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
PICBCKBE_02043	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
PICBCKBE_02044	2.51e-103	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
PICBCKBE_02045	8.2e-210	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PICBCKBE_02046	4.56e-136	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Proton-coupled thiamine transporter YuaJ
PICBCKBE_02047	5.07e-165	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
PICBCKBE_02048	3.34e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
PICBCKBE_02049	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PICBCKBE_02050	1.64e-206	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PICBCKBE_02051	1.58e-313	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_02053	9.19e-153	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PICBCKBE_02054	8.87e-120	rok	-	-	S	-	-	-	Repressor of ComK
PICBCKBE_02055	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PICBCKBE_02056	4.23e-269	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PICBCKBE_02057	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PICBCKBE_02058	3.9e-105	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
PICBCKBE_02059	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_02060	2.21e-156	csrR	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_02061	8.45e-283	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_02062	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
PICBCKBE_02063	0.0	yfnI	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
PICBCKBE_02065	1.48e-137	pap2c	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
PICBCKBE_02066	5.34e-182	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PICBCKBE_02067	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
PICBCKBE_02068	5.31e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PICBCKBE_02070	0.0	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
PICBCKBE_02071	5.42e-150	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
PICBCKBE_02072	1.42e-87	ypoP	-	-	K	-	-	-	transcriptional
PICBCKBE_02073	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PICBCKBE_02074	1.34e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
PICBCKBE_02076	1.12e-33	yozD	-	-	S	-	-	-	YozD-like protein
PICBCKBE_02077	1.11e-149	yodN	-	-	-	-	-	-	-
PICBCKBE_02078	2.13e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PICBCKBE_02079	1.08e-308	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	CHASE3 domain
PICBCKBE_02080	1.62e-28	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PICBCKBE_02081	5.45e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PICBCKBE_02082	4.5e-134	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PICBCKBE_02083	0.0	rsmF	-	-	J	-	-	-	RNA-binding PUA-like domain of methyltransferase RsmF
PICBCKBE_02084	1.95e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02085	9.68e-179	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
PICBCKBE_02086	1.5e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
PICBCKBE_02087	2.38e-119	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PICBCKBE_02088	3.07e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PICBCKBE_02089	9.63e-136	ypjP	-	-	S	-	-	-	YpjP-like protein
PICBCKBE_02090	2.03e-96	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
PICBCKBE_02091	5.73e-221	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
PICBCKBE_02092	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PICBCKBE_02093	7.49e-154	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
PICBCKBE_02094	1.86e-109	-	-	-	-	-	-	-	-
PICBCKBE_02095	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PICBCKBE_02096	3.17e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PICBCKBE_02097	4.69e-43	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
PICBCKBE_02098	1.59e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
PICBCKBE_02100	2.45e-214	ypcP	-	-	L	-	-	-	5'3' exonuclease
PICBCKBE_02101	7.1e-313	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PICBCKBE_02102	3.13e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PICBCKBE_02103	4.44e-224	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
PICBCKBE_02105	1.4e-48	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PICBCKBE_02106	3.22e-246	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PICBCKBE_02107	9e-08	-	-	-	-	-	-	-	-
PICBCKBE_02109	3.27e-47	-	-	-	S	-	-	-	protein secretion by the type IV secretion system
PICBCKBE_02110	2.41e-50	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
PICBCKBE_02111	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PICBCKBE_02112	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PICBCKBE_02113	4.31e-128	-	-	-	S	ko:K06328	-	ko00000	Outer spore coat protein E (CotE)
PICBCKBE_02114	1.8e-84	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
PICBCKBE_02115	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PICBCKBE_02116	0.0	-	2.6.1.82	-	E	ko:K09251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PICBCKBE_02117	0.0	-	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PICBCKBE_02118	0.0	-	-	-	KT	-	-	-	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PICBCKBE_02119	0.0	-	-	-	E	ko:K14052	-	ko00000,ko02000	Amino acid permease
PICBCKBE_02120	1.97e-316	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
PICBCKBE_02121	1.04e-217	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
PICBCKBE_02122	1.21e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
PICBCKBE_02123	1.02e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
PICBCKBE_02124	1.41e-304	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PICBCKBE_02125	1.53e-243	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PICBCKBE_02126	7.64e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PICBCKBE_02127	7.3e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PICBCKBE_02128	7.86e-186	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
PICBCKBE_02129	5.9e-188	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
PICBCKBE_02130	2.25e-54	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
PICBCKBE_02131	2.69e-186	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PICBCKBE_02132	1.74e-311	ymfH	-	-	S	-	-	-	zinc protease
PICBCKBE_02133	1.25e-302	albE	-	-	S	-	-	-	Peptidase M16
PICBCKBE_02134	4.58e-220	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PICBCKBE_02135	1.07e-239	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PICBCKBE_02136	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02137	1.43e-252	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
PICBCKBE_02138	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PICBCKBE_02139	6.67e-47	-	-	-	S	-	-	-	YlzJ-like protein
PICBCKBE_02140	1.18e-169	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
PICBCKBE_02141	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PICBCKBE_02142	1.35e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PICBCKBE_02143	7.04e-288	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PICBCKBE_02144	4.2e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PICBCKBE_02145	1.46e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PICBCKBE_02146	4.2e-241	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
PICBCKBE_02147	2.52e-51	ymxH	-	-	S	-	-	-	YlmC YmxH family
PICBCKBE_02148	3.54e-296	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
PICBCKBE_02149	1.41e-266	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
PICBCKBE_02150	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PICBCKBE_02151	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PICBCKBE_02152	6.65e-234	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PICBCKBE_02153	7.07e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PICBCKBE_02154	6.7e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PICBCKBE_02155	4.54e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
PICBCKBE_02156	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PICBCKBE_02157	3.02e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
PICBCKBE_02158	2.27e-59	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
PICBCKBE_02159	1.72e-285	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PICBCKBE_02160	2.23e-107	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PICBCKBE_02161	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PICBCKBE_02162	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PICBCKBE_02163	5.72e-301	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PICBCKBE_02164	7.66e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PICBCKBE_02165	3.27e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PICBCKBE_02166	3.43e-192	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PICBCKBE_02167	3.09e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PICBCKBE_02168	2.67e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PICBCKBE_02169	2.14e-201	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PICBCKBE_02170	1.05e-175	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PICBCKBE_02171	2.55e-112	ylxL	-	-	-	-	-	-	-
PICBCKBE_02172	3.94e-174	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_02173	5.54e-111	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PICBCKBE_02174	1.34e-145	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PICBCKBE_02175	2.9e-90	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
PICBCKBE_02176	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
PICBCKBE_02177	2.22e-152	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PICBCKBE_02178	2.83e-202	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
PICBCKBE_02179	7.68e-254	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
PICBCKBE_02180	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PICBCKBE_02181	2.15e-241	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PICBCKBE_02182	1.04e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
PICBCKBE_02183	3.82e-52	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
PICBCKBE_02184	1.16e-139	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
PICBCKBE_02185	1.13e-149	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
PICBCKBE_02186	2.57e-78	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
PICBCKBE_02187	1.17e-249	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PICBCKBE_02188	7.45e-233	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PICBCKBE_02189	1.89e-85	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
PICBCKBE_02190	5.79e-170	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
PICBCKBE_02191	1.51e-94	flg	-	-	N	-	-	-	Putative flagellar
PICBCKBE_02192	2.39e-139	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
PICBCKBE_02193	0.0	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control
PICBCKBE_02194	5.44e-85	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
PICBCKBE_02195	1.05e-93	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
PICBCKBE_02196	1.79e-315	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PICBCKBE_02197	2.1e-159	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
PICBCKBE_02198	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_02199	3.05e-218	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PICBCKBE_02200	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
PICBCKBE_02201	2.29e-55	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body complex protein FliE
PICBCKBE_02202	1.41e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
PICBCKBE_02203	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PICBCKBE_02204	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_02205	1.32e-173	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PICBCKBE_02206	1.24e-299	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PICBCKBE_02207	1.61e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PICBCKBE_02208	4.77e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
PICBCKBE_02211	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PICBCKBE_02212	5.55e-212	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
PICBCKBE_02213	6.5e-215	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PICBCKBE_02214	1.54e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PICBCKBE_02215	3.12e-61	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
PICBCKBE_02216	3.26e-293	-	-	-	D	-	-	-	nuclear chromosome segregation
PICBCKBE_02217	2.21e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PICBCKBE_02218	2.33e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PICBCKBE_02219	9.01e-132	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PICBCKBE_02220	6.22e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PICBCKBE_02221	1.15e-180	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PICBCKBE_02222	1.52e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PICBCKBE_02223	4.81e-81	-	-	-	S	-	-	-	YlqD protein
PICBCKBE_02224	4.15e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PICBCKBE_02225	4.31e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PICBCKBE_02226	1.81e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PICBCKBE_02227	4.33e-69	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PICBCKBE_02228	2.69e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PICBCKBE_02229	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PICBCKBE_02230	6.59e-172	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PICBCKBE_02231	1.64e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PICBCKBE_02232	1.04e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PICBCKBE_02233	1.77e-209	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
PICBCKBE_02234	2.07e-262	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PICBCKBE_02235	1.03e-126	fapR	-	-	Q	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PICBCKBE_02236	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PICBCKBE_02237	1.56e-199	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
PICBCKBE_02238	8.37e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
PICBCKBE_02239	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
PICBCKBE_02240	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02241	1.22e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PICBCKBE_02242	5.94e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PICBCKBE_02243	6.41e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PICBCKBE_02244	5.3e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PICBCKBE_02245	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PICBCKBE_02246	1.1e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PICBCKBE_02247	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PICBCKBE_02248	1.89e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PICBCKBE_02249	3.5e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PICBCKBE_02250	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PICBCKBE_02251	2.01e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PICBCKBE_02252	4e-40	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PICBCKBE_02253	2.24e-140	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PICBCKBE_02254	1.83e-60	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
PICBCKBE_02255	8.06e-200	yloC	-	-	S	-	-	-	stress-induced protein
PICBCKBE_02256	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
PICBCKBE_02257	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
PICBCKBE_02258	1.1e-209	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
PICBCKBE_02259	8.75e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PICBCKBE_02260	1.17e-115	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
PICBCKBE_02261	1.02e-13	-	-	-	L	ko:K07494	-	ko00000	DDE superfamily endonuclease
PICBCKBE_02262	2.08e-70	-	-	-	L	ko:K07499	-	ko00000	Transposase
PICBCKBE_02263	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PICBCKBE_02264	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_02266	6.08e-52	-	-	-	S	ko:K07077	-	ko00000	FAD binding domain
PICBCKBE_02267	4.17e-293	-	-	-	S	ko:K07077	-	ko00000	FAD binding domain
PICBCKBE_02268	1.21e-183	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
PICBCKBE_02269	1.53e-240	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
PICBCKBE_02270	2.81e-134	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PICBCKBE_02271	3.56e-134	-	-	-	P	ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PICBCKBE_02272	1.07e-171	-	-	-	P	ko:K15551	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
PICBCKBE_02273	2.29e-109	-	3.6.3.36	-	P	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PICBCKBE_02274	1.23e-38	-	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
PICBCKBE_02275	4.72e-141	-	-	-	Q	ko:K22303	-	ko00000,ko01000	Taurine catabolism dioxygenase TauD, TfdA family
PICBCKBE_02276	7.06e-126	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
PICBCKBE_02277	0.0	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
PICBCKBE_02278	1.41e-301	-	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_02279	1.08e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PICBCKBE_02280	3.01e-46	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
PICBCKBE_02282	4.15e-98	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
PICBCKBE_02283	8.8e-202	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PICBCKBE_02284	6.32e-315	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
PICBCKBE_02285	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PICBCKBE_02286	5.15e-214	-	-	-	K	-	-	-	AraC-like ligand binding domain
PICBCKBE_02288	3.03e-257	-	-	-	L	-	-	-	Transposase IS4 family protein
PICBCKBE_02289	3.19e-157	-	-	-	S	-	-	-	Nuclease-related domain
PICBCKBE_02290	5.33e-246	-	-	-	L	-	-	-	COG3039 Transposase and inactivated derivatives, IS5 family
PICBCKBE_02291	2.51e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PICBCKBE_02292	2.91e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PICBCKBE_02293	2.06e-218	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PICBCKBE_02294	3.29e-187	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PICBCKBE_02295	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
PICBCKBE_02296	2.98e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PICBCKBE_02297	9.71e-317	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PICBCKBE_02298	6.01e-215	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PICBCKBE_02299	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_02300	3e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PICBCKBE_02301	1.18e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PICBCKBE_02302	2.35e-107	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PICBCKBE_02304	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PICBCKBE_02305	8.55e-97	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
PICBCKBE_02306	6.37e-185	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
PICBCKBE_02307	3e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
PICBCKBE_02308	2.44e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PICBCKBE_02309	1.97e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PICBCKBE_02310	3.58e-199	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
PICBCKBE_02311	1.49e-114	-	-	-	M	-	-	-	3D domain
PICBCKBE_02312	2.63e-58	ylmC	-	-	S	-	-	-	sporulation protein
PICBCKBE_02313	7.67e-177	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_02314	1.59e-155	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PICBCKBE_02315	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_02316	1.54e-217	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PICBCKBE_02317	1.59e-247	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PICBCKBE_02318	5.93e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PICBCKBE_02319	1.19e-156	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PICBCKBE_02320	9.87e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PICBCKBE_02321	1.17e-248	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PICBCKBE_02322	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PICBCKBE_02323	2.75e-219	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PICBCKBE_02324	6.04e-103	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PICBCKBE_02325	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PICBCKBE_02326	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
PICBCKBE_02327	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PICBCKBE_02328	1.18e-69	ftsL	-	-	D	-	-	-	Essential cell division protein
PICBCKBE_02329	4.43e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PICBCKBE_02330	1.96e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PICBCKBE_02331	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PICBCKBE_02332	2.95e-207	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PICBCKBE_02333	1.12e-119	ylbP	-	-	K	-	-	-	n-acetyltransferase
PICBCKBE_02334	7.2e-109	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PICBCKBE_02335	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PICBCKBE_02336	9.36e-124	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
PICBCKBE_02337	2.13e-312	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PICBCKBE_02338	6.18e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PICBCKBE_02339	1.43e-179	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
PICBCKBE_02340	1.51e-278	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
PICBCKBE_02341	6.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PICBCKBE_02342	1.08e-136	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
PICBCKBE_02343	7.42e-89	-	-	-	S	-	-	-	Methylthioribose kinase
PICBCKBE_02344	7.56e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
PICBCKBE_02345	3.1e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
PICBCKBE_02346	2.52e-85	-	-	-	-	-	-	-	-
PICBCKBE_02347	5.16e-50	ylbE	-	-	S	-	-	-	YlbE-like protein
PICBCKBE_02348	2.04e-91	ylbD	-	-	S	-	-	-	Putative coat protein
PICBCKBE_02349	6.59e-111	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
PICBCKBE_02350	5.81e-249	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
PICBCKBE_02351	1.55e-83	ylbA	-	-	S	-	-	-	YugN-like family
PICBCKBE_02352	1.95e-223	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
PICBCKBE_02353	1.39e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PICBCKBE_02354	2.95e-147	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PICBCKBE_02355	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PICBCKBE_02356	3.56e-259	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PICBCKBE_02357	1.21e-212	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PICBCKBE_02358	7.37e-224	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PICBCKBE_02359	6.61e-277	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PICBCKBE_02360	1.4e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
PICBCKBE_02361	1.87e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PICBCKBE_02362	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
PICBCKBE_02363	2.12e-70	ylaH	-	-	S	-	-	-	YlaH-like protein
PICBCKBE_02364	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PICBCKBE_02365	1.1e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
PICBCKBE_02366	3.57e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
PICBCKBE_02367	3.19e-33	-	-	-	-	-	-	-	-
PICBCKBE_02368	2.85e-153	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
PICBCKBE_02369	2.12e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PICBCKBE_02371	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
PICBCKBE_02372	9.82e-09	-	-	-	S	-	-	-	SR1 protein
PICBCKBE_02373	5.15e-46	-	-	-	-	-	-	-	-
PICBCKBE_02374	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PICBCKBE_02375	1.41e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PICBCKBE_02376	2.48e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PICBCKBE_02377	3.06e-261	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PICBCKBE_02379	1.63e-39	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PICBCKBE_02380	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PICBCKBE_02381	1.25e-26	-	-	-	S	-	-	-	YhfH-like protein
PICBCKBE_02382	2.04e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PICBCKBE_02383	2.06e-122	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PICBCKBE_02384	4.04e-203	ccpC	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_02385	7.02e-103	ykuL	-	-	S	-	-	-	CBS domain
PICBCKBE_02386	7.13e-52	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02387	5.57e-217	-	3.5.1.4	-	C	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Acetamidase
PICBCKBE_02388	8.69e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_02389	9.15e-45	-	-	-	-	-	-	-	-
PICBCKBE_02390	9.11e-158	-	-	-	T	-	-	-	Diguanylate cyclase
PICBCKBE_02391	1.33e-224	-	-	-	T	-	-	-	Diguanylate cyclase
PICBCKBE_02392	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
PICBCKBE_02393	1.02e-112	ykyB	-	-	S	-	-	-	YkyB-like protein
PICBCKBE_02394	4.51e-206	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
PICBCKBE_02395	1.44e-274	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PICBCKBE_02396	1.84e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PICBCKBE_02397	1.23e-179	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_02398	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PICBCKBE_02399	2.6e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
PICBCKBE_02400	2.45e-48	-	-	-	-	-	-	-	-
PICBCKBE_02401	6.02e-37	ykvS	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02402	9.45e-138	-	-	-	S	ko:K07052	-	ko00000	Abortive infection protein
PICBCKBE_02403	3.24e-228	ykvI	-	-	S	-	-	-	membrane
PICBCKBE_02404	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PICBCKBE_02405	2.26e-06	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
PICBCKBE_02406	5.24e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
PICBCKBE_02407	3.16e-102	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PICBCKBE_02408	8.32e-31	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_02409	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_02410	3.86e-312	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_02412	3.9e-27	-	-	-	S	-	-	-	Stage 0 Sporulation Regulatory protein
PICBCKBE_02413	2.87e-39	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
PICBCKBE_02414	5.2e-184	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PICBCKBE_02415	2.92e-108	-	-	-	-	-	-	-	-
PICBCKBE_02416	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_02417	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PICBCKBE_02418	2.07e-263	kinA	2.7.13.3	-	T	ko:K02491,ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PICBCKBE_02419	1.92e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
PICBCKBE_02420	8.85e-97	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
PICBCKBE_02421	1.63e-158	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PICBCKBE_02422	6.6e-276	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PICBCKBE_02423	3.25e-97	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
PICBCKBE_02424	1.1e-178	-	4.1.1.77	-	Q	ko:K01617	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	COG3971 2-keto-4-pentenoate hydratase
PICBCKBE_02425	7.56e-62	-	-	-	-	-	-	-	-
PICBCKBE_02427	1.09e-221	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_02428	1.08e-122	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PICBCKBE_02430	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
PICBCKBE_02431	9.44e-234	ldhA	1.1.1.28	-	CH	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PICBCKBE_02432	5.75e-19	-	-	-	S	-	-	-	LXG domain of WXG superfamily
PICBCKBE_02433	4.42e-57	-	-	-	-	-	-	-	-
PICBCKBE_02435	5.77e-128	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PICBCKBE_02436	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PICBCKBE_02437	1.69e-161	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PICBCKBE_02438	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
PICBCKBE_02439	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major facilitator Superfamily
PICBCKBE_02440	7.21e-236	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_02443	4.84e-73	-	-	-	Q	-	-	-	domain protein
PICBCKBE_02444	0.0	yueB	-	-	S	-	-	-	domain protein
PICBCKBE_02445	3.52e-49	yueB	-	-	S	-	-	-	domain protein
PICBCKBE_02446	8.59e-60	esxA	-	-	S	-	-	-	Belongs to the WXG100 family
PICBCKBE_02447	9.6e-269	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
PICBCKBE_02448	1.04e-290	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PICBCKBE_02449	1.71e-206	-	-	-	K	-	-	-	Sensory domain found in PocR
PICBCKBE_02451	1.43e-47	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PICBCKBE_02452	1.52e-34	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PICBCKBE_02453	1.68e-108	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
PICBCKBE_02454	3.72e-132	-	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
PICBCKBE_02455	4.47e-121	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
PICBCKBE_02456	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_02457	0.0	-	6.2.1.16	-	I	ko:K01907	ko00280,ko00650,map00280,map00650	ko00000,ko00001,ko01000,ko01004	AMP-dependent synthetase
PICBCKBE_02458	5.27e-32	-	-	-	-	-	-	-	-
PICBCKBE_02459	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
PICBCKBE_02460	0.0	-	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction
PICBCKBE_02461	2.56e-316	mod	2.1.1.72, 3.1.21.5	-	L	ko:K01156,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
PICBCKBE_02462	8.9e-51	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PICBCKBE_02463	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
PICBCKBE_02464	1.78e-174	-	-	-	S	-	-	-	Phage capsid family
PICBCKBE_02465	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
PICBCKBE_02466	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
PICBCKBE_02467	2.62e-268	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
PICBCKBE_02468	3.78e-218	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02469	2.18e-169	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_02470	2.76e-216	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
PICBCKBE_02478	9.11e-182	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
PICBCKBE_02479	4.73e-123	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
PICBCKBE_02480	4.83e-98	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PICBCKBE_02482	2.02e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
PICBCKBE_02483	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_02485	2.49e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
PICBCKBE_02486	2.45e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
PICBCKBE_02487	2.91e-109	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
PICBCKBE_02488	1.4e-105	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PICBCKBE_02490	1.1e-78	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
PICBCKBE_02491	5.8e-110	-	-	-	S	ko:K06343,ko:K06344	-	ko00000	Spore coat protein
PICBCKBE_02494	3.26e-181	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PICBCKBE_02495	3.71e-182	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PICBCKBE_02496	3.59e-207	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PICBCKBE_02497	4.53e-197	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PICBCKBE_02498	2.41e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
PICBCKBE_02499	2.23e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
PICBCKBE_02500	2.97e-131	yjbK	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02501	2.21e-140	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PICBCKBE_02503	4.29e-120	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_02504	1.95e-93	-	-	-	L	-	-	-	transposase mutator type
PICBCKBE_02505	2.36e-96	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
PICBCKBE_02506	2.09e-208	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
PICBCKBE_02507	1.8e-08	-	-	-	-	-	-	-	-
PICBCKBE_02508	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PICBCKBE_02509	6.71e-307	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PICBCKBE_02510	1.02e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PICBCKBE_02511	8.61e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PICBCKBE_02512	1.38e-227	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_02513	1.81e-250	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_02514	2.61e-236	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PICBCKBE_02515	9.77e-206	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PICBCKBE_02516	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PICBCKBE_02517	2.36e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF3899)
PICBCKBE_02519	3.05e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
PICBCKBE_02520	2.24e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
PICBCKBE_02521	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
PICBCKBE_02522	9.14e-191	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
PICBCKBE_02523	3.64e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PICBCKBE_02524	4.46e-226	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_02525	9.27e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_02526	5.49e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
PICBCKBE_02527	6.18e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PICBCKBE_02528	7.63e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PICBCKBE_02530	9.83e-186	-	-	-	GM	-	-	-	ADP-glyceromanno-heptose 6-epimerase activity
PICBCKBE_02531	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PICBCKBE_02532	3.45e-37	yjzC	-	-	S	-	-	-	YjzC-like protein
PICBCKBE_02533	1.14e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
PICBCKBE_02534	4.9e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
PICBCKBE_02535	2.49e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
PICBCKBE_02536	1.92e-204	yitS	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02537	5.96e-206	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_02538	2.79e-136	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
PICBCKBE_02539	1.12e-78	yisL	-	-	S	-	-	-	UPF0344 protein
PICBCKBE_02540	7.6e-214	yisK	3.7.1.5	-	Q	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	ko00000,ko00001,ko01000	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PICBCKBE_02541	2.95e-285	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
PICBCKBE_02542	5.22e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
PICBCKBE_02543	1.03e-147	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
PICBCKBE_02544	2.75e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
PICBCKBE_02545	8.26e-96	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
PICBCKBE_02546	2.62e-40	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
PICBCKBE_02547	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PICBCKBE_02548	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
PICBCKBE_02549	3.03e-183	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
PICBCKBE_02550	3.57e-125	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
PICBCKBE_02552	6.23e-289	yhfN	-	-	O	-	-	-	Peptidase M48
PICBCKBE_02553	3.18e-56	-	-	-	S	-	-	-	branched-chain amino acid
PICBCKBE_02554	2.64e-153	ygaZ	-	-	E	-	-	-	AzlC protein
PICBCKBE_02555	0.0	lcfB_2	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Activates fatty acids by binding to coenzyme A
PICBCKBE_02556	9.5e-238	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PICBCKBE_02557	2.38e-29	yhfH	-	-	S	-	-	-	YhfH-like protein
PICBCKBE_02558	4.28e-84	ytkA	-	-	S	-	-	-	YtkA-like
PICBCKBE_02559	2.68e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PICBCKBE_02560	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PICBCKBE_02561	1.7e-211	-	-	-	EG	-	-	-	EamA-like transporter family
PICBCKBE_02562	1.13e-307	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
PICBCKBE_02563	2.02e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
PICBCKBE_02564	4.62e-183	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PICBCKBE_02565	1.04e-227	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PICBCKBE_02566	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
PICBCKBE_02567	7.94e-134	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_02568	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PICBCKBE_02569	2.07e-235	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PICBCKBE_02570	1.14e-252	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PICBCKBE_02571	7.85e-122	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PICBCKBE_02572	6.74e-305	yhfA	-	-	C	-	-	-	membrane
PICBCKBE_02573	1.07e-285	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PICBCKBE_02574	2.33e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PICBCKBE_02575	3.54e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
PICBCKBE_02576	4.71e-98	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PICBCKBE_02577	5.63e-108	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
PICBCKBE_02578	2.4e-47	yhaH	-	-	S	-	-	-	YtxH-like protein
PICBCKBE_02579	8.28e-135	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
PICBCKBE_02580	1.19e-71	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
PICBCKBE_02581	2.05e-197	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PICBCKBE_02582	2.41e-37	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
PICBCKBE_02583	7.73e-230	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
PICBCKBE_02584	0.0	yhaN	-	-	L	-	-	-	AAA domain
PICBCKBE_02585	1.64e-304	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
PICBCKBE_02586	9.57e-209	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
PICBCKBE_02587	3.16e-206	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
PICBCKBE_02589	9.1e-165	-	-	-	P	-	-	-	Integral membrane protein TerC family
PICBCKBE_02590	7.99e-37	-	-	-	S	-	-	-	YhzD-like protein
PICBCKBE_02591	2.29e-179	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
PICBCKBE_02592	3.08e-207	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
PICBCKBE_02593	1.58e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PICBCKBE_02594	2.35e-266	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
PICBCKBE_02595	0.0	-	-	-	HJ	-	-	-	YheC/D like ATP-grasp
PICBCKBE_02596	2.19e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
PICBCKBE_02597	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
PICBCKBE_02598	4.25e-292	-	-	-	HJ	-	-	-	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
PICBCKBE_02599	3.47e-212	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
PICBCKBE_02600	1.92e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PICBCKBE_02601	3.3e-39	B4168_3115	-	-	S	ko:K06419	-	ko00000	spore protein
PICBCKBE_02602	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PICBCKBE_02603	2.16e-22	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_02604	1.14e-201	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_02606	1.16e-133	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PICBCKBE_02607	6.85e-55	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
PICBCKBE_02608	1.17e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PICBCKBE_02609	9.76e-230	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PICBCKBE_02610	3.35e-215	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PICBCKBE_02611	1.35e-111	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
PICBCKBE_02612	6.59e-227	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PICBCKBE_02613	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
PICBCKBE_02614	1.25e-114	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
PICBCKBE_02615	1.4e-154	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PICBCKBE_02616	5.49e-197	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PICBCKBE_02617	4.27e-224	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PICBCKBE_02618	5.73e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
PICBCKBE_02619	2.04e-229	yvlB	-	-	S	-	-	-	Putative adhesin
PICBCKBE_02620	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PICBCKBE_02621	1.23e-187	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
PICBCKBE_02622	6.31e-295	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PICBCKBE_02623	9.55e-286	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PICBCKBE_02624	7.34e-95	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
PICBCKBE_02625	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PICBCKBE_02626	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PICBCKBE_02627	1.55e-15	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2164)
PICBCKBE_02628	2.74e-46	csbA	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02629	3.57e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PICBCKBE_02630	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_02631	9.05e-67	-	-	-	S	ko:K12962	ko01503,map01503	ko00000,ko00001,ko00002,ko01005,ko02000	EamA-like transporter family
PICBCKBE_02632	3.85e-74	-	-	-	P	-	-	-	EamA-like transporter family
PICBCKBE_02633	0.0	-	-	-	-	-	-	-	-
PICBCKBE_02634	1.17e-220	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PICBCKBE_02636	3.27e-184	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PICBCKBE_02637	9.79e-194	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PICBCKBE_02638	3.7e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
PICBCKBE_02639	5.24e-209	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PICBCKBE_02640	4.17e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PICBCKBE_02641	0.0	hemG	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PICBCKBE_02642	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
PICBCKBE_02643	2.13e-160	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PICBCKBE_02644	5.47e-35	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
PICBCKBE_02645	6.09e-57	fdxA	-	-	C	-	-	-	4Fe-4S binding domain
PICBCKBE_02646	6.84e-226	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
PICBCKBE_02647	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02648	2.06e-210	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PICBCKBE_02649	3.57e-211	fatD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PICBCKBE_02650	9.26e-290	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PICBCKBE_02651	3.47e-186	-	-	-	L	-	-	-	transposase mutator type
PICBCKBE_02653	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PICBCKBE_02654	5.45e-232	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PICBCKBE_02655	1.23e-313	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
PICBCKBE_02656	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PICBCKBE_02657	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_02658	1.19e-181	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
PICBCKBE_02659	2.14e-201	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PICBCKBE_02660	7.33e-177	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
PICBCKBE_02662	8.82e-68	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
PICBCKBE_02663	8.76e-202	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PICBCKBE_02664	5.23e-230	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PICBCKBE_02665	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PICBCKBE_02666	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
PICBCKBE_02667	8.95e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PICBCKBE_02669	8.14e-75	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
PICBCKBE_02670	1.94e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
PICBCKBE_02671	2.09e-290	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PICBCKBE_02672	5.15e-79	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
PICBCKBE_02674	2.93e-135	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PICBCKBE_02676	0.0	-	-	-	L	-	-	-	Transposase
PICBCKBE_02677	0.0	-	-	-	O	-	-	-	AAA domain
PICBCKBE_02678	4.05e-103	-	-	-	E	-	-	-	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_02679	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_02680	1.66e-84	-	-	-	E	-	-	-	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_02682	2.8e-311	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PICBCKBE_02683	6.64e-187	-	-	-	G	ko:K10709	-	ko00000	myo-inosose-2 dehydratase activity
PICBCKBE_02684	1.62e-191	-	-	-	G	-	-	-	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PICBCKBE_02685	1.52e-145	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
PICBCKBE_02686	2.19e-125	-	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
PICBCKBE_02687	6.08e-236	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PICBCKBE_02688	1.67e-123	-	-	-	U	-	-	-	SEC-C motif
PICBCKBE_02689	1.96e-31	-	-	-	S	-	-	-	Nucleotidyltransferase domain
PICBCKBE_02690	3.42e-45	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PICBCKBE_02691	9.57e-106	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PICBCKBE_02692	1.7e-204	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
PICBCKBE_02693	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
PICBCKBE_02694	2.9e-99	yvyG	-	-	NOU	-	-	-	FlgN protein
PICBCKBE_02695	1.24e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
PICBCKBE_02696	2.2e-91	yvyF	-	-	S	-	-	-	flagellar protein
PICBCKBE_02697	1.63e-171	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
PICBCKBE_02698	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PICBCKBE_02700	3.3e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_02701	0.0	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
PICBCKBE_02702	2.8e-159	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PICBCKBE_02703	5.7e-262	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PICBCKBE_02704	2.07e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
PICBCKBE_02705	3.9e-225	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PICBCKBE_02706	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
PICBCKBE_02707	1.28e-313	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PICBCKBE_02708	3.01e-251	cwlS	-	CBM50	M	ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PICBCKBE_02709	5e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
PICBCKBE_02710	1.69e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PICBCKBE_02711	4.41e-270	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PICBCKBE_02712	0.0	bmr3_1	-	-	P	ko:K18935	-	ko00000,ko02000	Major facilitator superfamily
PICBCKBE_02713	6.09e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PICBCKBE_02714	1.52e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PICBCKBE_02716	6.3e-91	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PICBCKBE_02717	2.63e-207	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
PICBCKBE_02719	9.05e-22	-	-	-	-	-	-	-	-
PICBCKBE_02720	1.15e-43	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
PICBCKBE_02721	3.05e-234	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_02722	2.6e-260	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
PICBCKBE_02723	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PICBCKBE_02724	8.2e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PICBCKBE_02725	1.46e-283	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PICBCKBE_02726	2.16e-21	-	-	-	-	-	-	-	-
PICBCKBE_02727	2.69e-23	-	-	-	I	-	-	-	acyl-CoA dehydrogenase activity
PICBCKBE_02728	1.67e-270	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
PICBCKBE_02731	1.95e-176	lppC	-	-	M	-	-	-	5'-nucleotidase, lipoprotein e(P4)
PICBCKBE_02732	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
PICBCKBE_02733	2.69e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PICBCKBE_02734	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
PICBCKBE_02735	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_02736	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PICBCKBE_02737	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_02738	1.92e-262	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PICBCKBE_02739	8.19e-47	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
PICBCKBE_02740	1.29e-172	-	-	-	GKT	ko:K03483	-	ko00000,ko03000	transcriptional antiterminator
PICBCKBE_02741	9.45e-104	yjhE	-	-	S	-	-	-	Phage tail protein
PICBCKBE_02742	0.0	-	-	-	FH	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
PICBCKBE_02743	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PICBCKBE_02744	2.81e-57	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
PICBCKBE_02745	1.23e-40	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
PICBCKBE_02746	2.94e-189	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PICBCKBE_02747	8.28e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
PICBCKBE_02748	1.53e-52	-	-	-	-	-	-	-	-
PICBCKBE_02749	3.29e-187	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
PICBCKBE_02750	0.0	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PICBCKBE_02751	3.05e-67	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PICBCKBE_02752	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha-galactosidase
PICBCKBE_02753	3.27e-134	-	4.1.3.17	-	H	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	ko00000,ko00001,ko01000	Methyltransferase
PICBCKBE_02754	1.41e-285	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PICBCKBE_02755	1.7e-141	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
PICBCKBE_02756	2.84e-57	-	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
PICBCKBE_02757	3.38e-81	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
PICBCKBE_02759	1.88e-315	-	-	-	V	-	-	-	Mate efflux family protein
PICBCKBE_02760	1.44e-196	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
PICBCKBE_02761	0.0	-	-	-	L	-	-	-	AAA domain
PICBCKBE_02762	1.62e-314	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Calcineurin-like phosphoesterase superfamily domain
PICBCKBE_02763	1.31e-129	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
PICBCKBE_02764	6.41e-197	morA	-	-	S	-	-	-	Aldo/keto reductase family
PICBCKBE_02765	1.9e-177	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PICBCKBE_02766	8.74e-58	-	-	-	M	-	-	-	Spore coat protein
PICBCKBE_02767	1.25e-71	-	-	-	M	-	-	-	Spore coat protein
PICBCKBE_02768	1.97e-230	-	-	-	C	-	-	-	Aldo/keto reductase family
PICBCKBE_02769	0.0	ubiE2	-	-	Q	-	-	-	Methyltransferase domain
PICBCKBE_02770	2.1e-85	ubiE2	-	-	Q	-	-	-	Methyltransferase domain
PICBCKBE_02771	6.64e-185	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	BAAT / Acyl-CoA thioester hydrolase C terminal
PICBCKBE_02773	1.84e-189	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
PICBCKBE_02774	5.86e-122	hxlB	4.1.2.43, 5.3.1.27	-	M	ko:K08093,ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	arabinose-5-phosphate isomerase activity
PICBCKBE_02775	5.9e-232	ykvZ	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_02776	3.37e-112	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
PICBCKBE_02777	5.68e-114	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
PICBCKBE_02778	7.16e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PICBCKBE_02779	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
PICBCKBE_02781	2.95e-287	yfkA	-	-	S	-	-	-	YfkB-like domain
PICBCKBE_02782	1.49e-98	-	-	-	-	-	-	-	-
PICBCKBE_02783	4.69e-39	-	-	-	-	-	-	-	-
PICBCKBE_02784	1.14e-91	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
PICBCKBE_02785	4.37e-287	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PICBCKBE_02786	3.71e-197	yokD	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	aminoglycoside
PICBCKBE_02787	2.44e-213	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_02788	0.0	-	-	-	I	-	-	-	Acyl-CoA dehydrogenase, middle domain
PICBCKBE_02789	0.0	-	6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_02790	1.02e-81	-	-	-	K	-	-	-	transcriptional
PICBCKBE_02791	9.2e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
PICBCKBE_02793	8.39e-180	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
PICBCKBE_02794	1.08e-101	-	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PICBCKBE_02795	2.82e-111	-	-	-	-	-	-	-	-
PICBCKBE_02796	1.66e-269	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
PICBCKBE_02797	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PICBCKBE_02798	0.0	-	-	-	L	-	-	-	Transposase, IS4 family protein
PICBCKBE_02799	4.08e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mg2 transporter protein CorA family protein
PICBCKBE_02802	1.53e-306	panF	-	-	H	ko:K14392	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PICBCKBE_02803	7.03e-62	-	-	-	S	-	-	-	Sodium pantothenate symporter
PICBCKBE_02804	3.21e-212	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PICBCKBE_02805	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PICBCKBE_02806	9.66e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
PICBCKBE_02807	1.46e-30	-	-	-	E	-	-	-	Belongs to the arginase family
PICBCKBE_02808	1.84e-189	-	-	-	E	-	-	-	Belongs to the arginase family
PICBCKBE_02809	1.22e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PICBCKBE_02810	9.28e-249	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PICBCKBE_02811	1.47e-214	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PICBCKBE_02812	3.42e-180	-	-	-	P	ko:K02049,ko:K15600	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02813	1.47e-243	M1-596	-	-	P	ko:K02051,ko:K15598	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PICBCKBE_02814	8.33e-183	-	-	-	P	ko:K15599	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
PICBCKBE_02815	1.4e-154	-	-	-	S	-	-	-	Thiamine-binding protein
PICBCKBE_02817	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PICBCKBE_02818	6.59e-106	-	-	-	S	-	-	-	Heat induced stress protein YflT
PICBCKBE_02819	1.92e-211	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PICBCKBE_02820	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
PICBCKBE_02821	1.13e-270	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
PICBCKBE_02822	2.74e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PICBCKBE_02823	1.04e-217	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PICBCKBE_02824	3.45e-174	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PICBCKBE_02825	9.73e-228	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
PICBCKBE_02826	4.91e-110	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PICBCKBE_02827	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
PICBCKBE_02828	0.0	-	-	-	S	-	-	-	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PICBCKBE_02829	1.69e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
PICBCKBE_02830	2.13e-64	yqgV	-	-	S	-	-	-	Thiamine-binding protein
PICBCKBE_02831	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
PICBCKBE_02832	7.71e-128	-	-	-	KT	-	-	-	HD domain
PICBCKBE_02834	2.23e-155	yabE	-	-	S	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	3D domain
PICBCKBE_02835	3.52e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PICBCKBE_02837	0.0	ppc	4.1.1.31	-	C	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PICBCKBE_02838	1.18e-41	-	-	-	-	-	-	-	-
PICBCKBE_02839	4.12e-183	-	-	-	L	-	-	-	transposase mutator type
PICBCKBE_02840	5.85e-24	macB1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
PICBCKBE_02841	9.58e-214	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PICBCKBE_02842	2.06e-157	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
PICBCKBE_02843	9.52e-212	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PICBCKBE_02844	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PICBCKBE_02845	6.98e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
PICBCKBE_02846	6.37e-42	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
PICBCKBE_02847	2.4e-168	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
PICBCKBE_02848	1.23e-188	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PICBCKBE_02849	1.08e-111	-	-	-	-	-	-	-	-
PICBCKBE_02850	8.19e-96	-	3.4.21.121	-	O	ko:K20755	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
PICBCKBE_02851	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
PICBCKBE_02852	6.68e-206	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PICBCKBE_02853	2.92e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
PICBCKBE_02854	2.27e-69	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PICBCKBE_02855	1.06e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PICBCKBE_02856	1.49e-169	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PICBCKBE_02857	8.72e-298	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PICBCKBE_02858	2e-282	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PICBCKBE_02859	3.14e-189	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PICBCKBE_02860	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
PICBCKBE_02861	3.84e-278	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PICBCKBE_02862	3.17e-277	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PICBCKBE_02863	1.34e-09	-	-	-	S	-	-	-	ABC-2 family transporter protein
PICBCKBE_02864	1.26e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PICBCKBE_02865	2.04e-226	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the SIS family. GutQ KpsF subfamily
PICBCKBE_02866	5.7e-199	kdsA	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
PICBCKBE_02867	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
PICBCKBE_02868	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PICBCKBE_02869	9.22e-317	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PICBCKBE_02870	1.58e-106	-	-	-	-	-	-	-	-
PICBCKBE_02871	4.19e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PICBCKBE_02872	1.02e-67	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_02873	2.01e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
PICBCKBE_02874	0.0	wprA	-	-	O	ko:K13274,ko:K20276	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PICBCKBE_02875	2.97e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF1659)
PICBCKBE_02876	1.62e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PICBCKBE_02877	3.26e-23	-	-	-	S	-	-	-	YvrJ protein family
PICBCKBE_02878	3.21e-47	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
PICBCKBE_02879	4.46e-168	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
PICBCKBE_02880	2.07e-280	-	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_02881	7.6e-216	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PICBCKBE_02883	3.37e-79	-	-	-	-	-	-	-	-
PICBCKBE_02884	7.28e-290	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PICBCKBE_02885	2.66e-157	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
PICBCKBE_02886	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PICBCKBE_02887	1.43e-30	-	-	-	S	-	-	-	Zinc-ribbon containing domain
PICBCKBE_02888	9.45e-315	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
PICBCKBE_02889	4.24e-216	-	3.5.1.4	-	C	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Acetamidase
PICBCKBE_02891	9.79e-168	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
PICBCKBE_02892	8.3e-171	-	-	-	T	-	-	-	Histidine kinase
PICBCKBE_02893	2.74e-24	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
PICBCKBE_02894	1.98e-66	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
PICBCKBE_02896	2.86e-57	-	-	-	-	-	-	-	-
PICBCKBE_02897	1.86e-163	-	-	-	-	-	-	-	-
PICBCKBE_02898	9.95e-61	-	-	-	T	-	-	-	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PICBCKBE_02899	1.97e-59	-	-	-	-	-	-	-	-
PICBCKBE_02901	5.3e-264	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
PICBCKBE_02902	5.22e-16	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_02903	0.0	-	1.3.1.31	-	C	ko:K10797	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PICBCKBE_02904	5.76e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PICBCKBE_02905	6.27e-249	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PICBCKBE_02906	1.67e-127	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
PICBCKBE_02907	1.09e-292	-	-	-	L	-	-	-	PFAM Transposase, IS116 IS110 IS902
PICBCKBE_02908	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
PICBCKBE_02909	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5110)
PICBCKBE_02910	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
PICBCKBE_02911	1.63e-278	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PICBCKBE_02912	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PICBCKBE_02913	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
PICBCKBE_02914	1.82e-158	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PICBCKBE_02915	8.2e-210	XK27_10120	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
PICBCKBE_02916	5.11e-28	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PICBCKBE_02917	6.62e-58	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PICBCKBE_02918	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PICBCKBE_02919	5.58e-185	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
PICBCKBE_02920	0.0	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PICBCKBE_02922	1.06e-185	fnt	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
PICBCKBE_02923	1.39e-124	-	-	-	S	-	-	-	NYN domain
PICBCKBE_02924	4.05e-265	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PICBCKBE_02925	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
PICBCKBE_02926	9.52e-204	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
PICBCKBE_02927	3.74e-265	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PICBCKBE_02928	9.1e-281	xylR	-	-	GK	-	-	-	ROK family
PICBCKBE_02929	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
PICBCKBE_02930	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
PICBCKBE_02931	1.81e-316	xylT	-	-	U	ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PICBCKBE_02932	2.49e-256	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
PICBCKBE_02933	3.69e-30	-	-	-	-	-	-	-	-
PICBCKBE_02934	1.69e-197	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_02935	0.0	comM	-	-	O	ko:K07391	-	ko00000	Mg chelatase subunit ChlI
PICBCKBE_02936	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
PICBCKBE_02937	1.16e-285	mvaS	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
PICBCKBE_02938	0.0	-	-	-	L	-	-	-	RNA-directed DNA polymerase (reverse transcriptase)
PICBCKBE_02939	9.08e-175	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PICBCKBE_02940	5.58e-181	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
PICBCKBE_02941	8.6e-138	yjlB	-	-	S	-	-	-	Cupin domain
PICBCKBE_02942	4.33e-62	-	-	-	-	-	-	-	-
PICBCKBE_02943	9.78e-257	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PICBCKBE_02944	5.39e-130	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
PICBCKBE_02945	8.34e-127	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
PICBCKBE_02946	2.46e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PICBCKBE_02947	5.03e-148	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PICBCKBE_02948	6.78e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PICBCKBE_02949	1.41e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PICBCKBE_02950	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
PICBCKBE_02952	1.66e-222	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_02953	7.34e-271	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PICBCKBE_02954	1.38e-97	ywoH	-	-	K	-	-	-	transcriptional
PICBCKBE_02955	1.85e-238	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
PICBCKBE_02956	6.72e-286	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PICBCKBE_02957	0.0	-	3.2.1.37	GH43	K	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	helix_turn_helix, arabinose operon control protein
PICBCKBE_02958	0.0	-	-	-	E	-	-	-	Amino acid permease
PICBCKBE_02960	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	MFS/sugar transport protein
PICBCKBE_02961	2.93e-298	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PICBCKBE_02962	1.47e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PICBCKBE_02963	1.39e-70	ptcA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS cellobiose transporter subunit IIA
PICBCKBE_02964	5.21e-71	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_02965	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
PICBCKBE_02966	1.33e-273	-	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_02967	2.17e-243	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
PICBCKBE_02968	6.98e-286	-	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
PICBCKBE_02969	1.32e-291	-	1.3.99.32	-	I	ko:K16173	ko00362,ko01120,map00362,map01120	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, N-terminal domain
PICBCKBE_02970	1.57e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF3870)
PICBCKBE_02972	3.94e-25	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_02973	4.73e-205	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_02974	2.67e-221	ydhF	-	-	S	-	-	-	Oxidoreductase
PICBCKBE_02975	4.78e-79	-	-	-	-	-	-	-	-
PICBCKBE_02977	4.43e-224	-	-	-	K	-	-	-	cell envelope-related transcriptional attenuator
PICBCKBE_02979	0.0	ybeC	-	-	E	-	-	-	amino acid
PICBCKBE_02980	3.27e-27	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
PICBCKBE_02981	4.18e-237	csd1	-	-	S	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein, Csd1 family
PICBCKBE_02982	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
PICBCKBE_02983	1.37e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF3006)
PICBCKBE_02984	0.0	-	-	-	L	-	-	-	Metallo-beta-lactamase superfamily
PICBCKBE_02985	1e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
PICBCKBE_02986	1.52e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
PICBCKBE_02987	1.13e-89	-	-	-	S	-	-	-	YjbR
PICBCKBE_02988	4.48e-231	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PICBCKBE_02989	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
PICBCKBE_02990	1.92e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
PICBCKBE_02991	1.74e-291	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
PICBCKBE_02992	0.0	-	-	-	EQ	-	-	-	Hydantoinase oxoprolinase
PICBCKBE_02993	2.36e-270	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
PICBCKBE_02994	0.0	-	-	-	K	-	-	-	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PICBCKBE_02995	1.93e-109	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
PICBCKBE_02996	2.65e-76	-	2.7.1.56	-	F	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PICBCKBE_02998	5.8e-251	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PICBCKBE_02999	2.45e-40	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	to PTS system galactitol-specific enzyme IIB component
PICBCKBE_03000	9.74e-19	-	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PICBCKBE_03001	3.29e-211	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
PICBCKBE_03002	1.96e-253	-	-	-	M	-	-	-	SIS domain
PICBCKBE_03003	1.13e-183	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PFAM Phosphotransferase system, mannose fructose sorbose family IID component
PICBCKBE_03004	9.17e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PICBCKBE_03005	8.95e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
PICBCKBE_03006	1.26e-95	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PICBCKBE_03007	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	PTS system fructose IIA component
PICBCKBE_03008	0.0	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
PICBCKBE_03009	0.0	-	3.5.2.14	-	EQ	ko:K01474	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
PICBCKBE_03010	0.0	-	3.5.2.14	-	EQ	ko:K01473	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
PICBCKBE_03011	4.47e-126	-	-	-	K	-	-	-	Cupin domain
PICBCKBE_03012	1.28e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PICBCKBE_03013	3.04e-171	-	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PICBCKBE_03014	2.81e-106	-	2.7.1.191	-	G	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PICBCKBE_03015	6.56e-182	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PICBCKBE_03016	1.01e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PICBCKBE_03017	3.82e-95	agaF	2.7.1.191	-	G	ko:K02744,ko:K02793	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PICBCKBE_03018	1.32e-67	-	-	-	L	-	-	-	Transposase
PICBCKBE_03019	2.63e-51	-	-	-	-	-	-	-	-
PICBCKBE_03020	4.1e-137	-	-	-	S	-	-	-	Protein of unknown function DUF262
PICBCKBE_03021	1.88e-89	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	N-4 methylation of cytosine
PICBCKBE_03022	1.35e-156	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
PICBCKBE_03023	4.66e-151	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_03024	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_03026	1.5e-168	yodH	-	-	Q	-	-	-	Methyltransferase
PICBCKBE_03027	1.57e-186	yjaZ	-	-	O	-	-	-	Zn-dependent protease
PICBCKBE_03028	7.07e-44	yodI	-	-	-	-	-	-	-
PICBCKBE_03029	1.82e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PICBCKBE_03030	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PICBCKBE_03031	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_03035	1.51e-234	-	-	-	I	-	-	-	Alpha beta hydrolase
PICBCKBE_03036	1.59e-93	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PICBCKBE_03038	5.69e-283	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PICBCKBE_03039	7.05e-270	-	-	-	GK	-	-	-	ROK family
PICBCKBE_03040	1.38e-179	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_03041	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
PICBCKBE_03042	9.42e-313	-	-	-	G	-	-	-	MFS/sugar transport protein
PICBCKBE_03043	2.14e-46	-	-	-	-	-	-	-	-
PICBCKBE_03044	8.73e-175	-	-	-	E	-	-	-	IrrE N-terminal-like domain
PICBCKBE_03045	1.68e-78	-	-	-	S	-	-	-	Helix-turn-helix
PICBCKBE_03046	0.0	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	Peptidase M30
PICBCKBE_03047	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
PICBCKBE_03048	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
PICBCKBE_03049	1.71e-253	xylP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PICBCKBE_03050	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
PICBCKBE_03051	5.31e-146	xylR	-	-	GK	-	-	-	Transcriptional regulator
PICBCKBE_03052	5.48e-215	-	-	-	S	ko:K07459	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PICBCKBE_03053	9.41e-136	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PICBCKBE_03054	1.64e-114	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PICBCKBE_03055	1.14e-295	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PICBCKBE_03056	3.09e-240	-	2.7.7.13	-	G	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
PICBCKBE_03057	8.15e-42	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PICBCKBE_03058	2.49e-33	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
PICBCKBE_03059	8.48e-44	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
PICBCKBE_03061	2.11e-45	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
PICBCKBE_03062	7.34e-43	-	-	-	S	-	-	-	Membrane protein involved in the export of O-antigen and teichoic acid
PICBCKBE_03063	3.09e-116	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PICBCKBE_03064	1.73e-191	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PICBCKBE_03065	8.34e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
PICBCKBE_03066	6.23e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
PICBCKBE_03067	5.91e-154	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
PICBCKBE_03068	2.07e-196	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PICBCKBE_03069	1.72e-136	-	2.7.7.6	-	K	ko:K00960	-	ko00000,ko01000	Belongs to the sigma-70 factor family. ECF subfamily
PICBCKBE_03070	1.62e-115	-	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	ComK protein
PICBCKBE_03071	1.03e-21	csbD	-	-	S	-	-	-	Belongs to the UPF0337 (CsbD) family
PICBCKBE_03072	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
PICBCKBE_03073	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PICBCKBE_03075	2.13e-209	msrR	-	-	K	-	-	-	COG1316 Transcriptional regulator
PICBCKBE_03076	1.16e-135	yngC	-	-	S	-	-	-	membrane-associated protein
PICBCKBE_03077	8.46e-301	-	-	-	S	-	-	-	SNARE associated Golgi protein
PICBCKBE_03079	1.25e-72	yodB	-	-	K	-	-	-	transcriptional
PICBCKBE_03080	1.01e-251	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
PICBCKBE_03081	1.04e-90	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PICBCKBE_03082	3.08e-151	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PICBCKBE_03083	1.04e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PICBCKBE_03084	2.08e-176	glnH	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PICBCKBE_03085	9.76e-172	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PICBCKBE_03086	1.02e-218	ydbI	-	-	S	-	-	-	AI-2E family transporter
PICBCKBE_03087	1.83e-33	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PICBCKBE_03088	3.25e-188	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PICBCKBE_03089	0.0	ydaO	-	-	E	-	-	-	amino acid
PICBCKBE_03091	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
PICBCKBE_03092	9.18e-242	cnpD2	-	-	T	-	-	-	HD domain
PICBCKBE_03095	3.25e-274	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PICBCKBE_03096	2.6e-124	-	-	-	S	-	-	-	Belongs to the UPF0312 family
PICBCKBE_03097	2.06e-169	-	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PICBCKBE_03099	1.75e-157	-	-	-	K	ko:K10914,ko:K21828	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PICBCKBE_03100	5e-276	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PICBCKBE_03101	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PICBCKBE_03102	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PICBCKBE_03103	3.84e-190	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PICBCKBE_03104	1.55e-129	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PICBCKBE_03107	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PICBCKBE_03108	1.83e-234	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
PICBCKBE_03109	6.47e-303	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
PICBCKBE_03110	1.01e-156	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PICBCKBE_03111	0.0	citS	2.7.13.3	-	T	ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
PICBCKBE_03112	1.4e-300	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
PICBCKBE_03113	1.11e-283	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
PICBCKBE_03115	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
PICBCKBE_03117	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
PICBCKBE_03118	1.15e-299	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
PICBCKBE_03119	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PICBCKBE_03120	0.0	pucI	-	-	FH	ko:K03457	-	ko00000	COG1953 Cytosine uracil thiamine allantoin permeases
PICBCKBE_03121	3.81e-294	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PICBCKBE_03122	3e-271	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
PICBCKBE_03123	0.0	-	2.6.1.55	-	H	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	ko00000,ko00001,ko01000	Aminotransferase class-III
PICBCKBE_03124	6.65e-281	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Transcriptional regulator
PICBCKBE_03125	7.19e-177	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PICBCKBE_03126	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PICBCKBE_03127	1.34e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PICBCKBE_03128	0.0	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
PICBCKBE_03129	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03130	0.0	-	-	-	H	-	-	-	HemY protein
PICBCKBE_03132	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03133	3.24e-246	-	-	-	L	-	-	-	COG3039 Transposase and inactivated derivatives, IS5 family
PICBCKBE_03134	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03135	1.06e-260	potD	-	-	E	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
PICBCKBE_03136	7.93e-179	potC	-	-	E	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1177 ABC-type spermidine putrescine transport system, permease component II
PICBCKBE_03137	2.89e-179	potB	-	-	E	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
PICBCKBE_03138	8.87e-269	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PICBCKBE_03139	1.6e-128	-	-	-	K	-	-	-	Cupin domain
PICBCKBE_03141	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
PICBCKBE_03142	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
PICBCKBE_03143	4.11e-25	-	-	-	-	-	-	-	-
PICBCKBE_03144	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
PICBCKBE_03145	4.25e-128	-	-	-	C	-	-	-	Nitroreductase family
PICBCKBE_03146	1.67e-222	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PICBCKBE_03147	4.58e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
PICBCKBE_03148	1.49e-121	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
PICBCKBE_03149	6.33e-132	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
PICBCKBE_03150	1.8e-307	-	-	-	G	ko:K03535	-	ko00000,ko02000	Major Facilitator Superfamily
PICBCKBE_03151	1.39e-230	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
PICBCKBE_03152	7.95e-171	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PICBCKBE_03153	2.36e-246	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
PICBCKBE_03154	2.86e-315	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PICBCKBE_03155	6.35e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PICBCKBE_03157	6.59e-143	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PICBCKBE_03158	2.47e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PICBCKBE_03159	1.78e-171	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	Mannitol dehydrogenase Rossmann domain
PICBCKBE_03160	8.71e-195	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PICBCKBE_03161	9.71e-294	mtlA	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PICBCKBE_03162	2.26e-302	-	-	-	L	-	-	-	Transposase DDE domain group 1
PICBCKBE_03163	2.24e-96	-	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_03164	4.91e-30	-	-	-	-	-	-	-	-
PICBCKBE_03165	1.5e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
PICBCKBE_03166	1.56e-237	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases C terminal
PICBCKBE_03167	5.55e-220	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
PICBCKBE_03168	1.58e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases C terminal
PICBCKBE_03169	7.15e-142	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PICBCKBE_03170	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PICBCKBE_03171	5.25e-209	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
PICBCKBE_03172	1.07e-39	-	-	-	-	-	-	-	-
PICBCKBE_03173	8.73e-60	-	-	-	-	-	-	-	-
PICBCKBE_03174	3.83e-202	-	-	-	S	-	-	-	Nuclease-related domain
PICBCKBE_03175	2.64e-214	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PICBCKBE_03177	1.78e-242	-	-	-	T	ko:K20971	ko02025,map02025	ko00000,ko00001,ko01001,ko02022	Diguanylate cyclase, GGDEF domain
PICBCKBE_03178	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_03179	5.71e-261	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
PICBCKBE_03180	4.29e-120	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03181	2.47e-77	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03182	2.61e-123	ywhH	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
PICBCKBE_03183	2.5e-139	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
PICBCKBE_03184	3.81e-171	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
PICBCKBE_03185	8.69e-180	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
PICBCKBE_03186	2.61e-180	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
PICBCKBE_03188	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
PICBCKBE_03189	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PICBCKBE_03190	1.43e-251	-	-	-	S	-	-	-	Phosphotransferase enzyme family
PICBCKBE_03191	5.34e-89	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
PICBCKBE_03193	2.1e-123	-	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_03194	5.9e-91	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_03195	2.17e-220	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PICBCKBE_03196	2.89e-176	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PICBCKBE_03197	7.27e-306	bbsG	1.3.8.7	-	I	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	ko00000,ko00001,ko00002,ko01000	COG1960 Acyl-CoA dehydrogenases
PICBCKBE_03198	9.24e-246	-	-	-	T	ko:K17763	-	ko00000,ko03021	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
PICBCKBE_03199	6.56e-164	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
PICBCKBE_03200	1.04e-136	-	-	-	-	-	-	-	-
PICBCKBE_03201	2.4e-129	-	-	-	-	-	-	-	-
PICBCKBE_03202	1.56e-144	-	-	-	-	-	-	-	-
PICBCKBE_03203	2.28e-248	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PICBCKBE_03204	2.06e-192	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PICBCKBE_03205	2.79e-226	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PICBCKBE_03206	1.44e-233	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PICBCKBE_03207	4.95e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PICBCKBE_03208	2.2e-177	yfcA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PICBCKBE_03209	3.62e-68	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
PICBCKBE_03210	1.17e-62	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
PICBCKBE_03211	7.22e-148	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PICBCKBE_03212	1.8e-120	-	-	-	Q	-	-	-	Thioesterase superfamily
PICBCKBE_03213	6.52e-24	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_03214	1.14e-27	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_03215	1.05e-29	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_03216	1.18e-90	-	-	-	S	-	-	-	transposase or invertase
PICBCKBE_03217	4.53e-264	crtQ	-	-	M	ko:K10211	ko00906,map00906	ko00000,ko00001,ko01000	Glycosyl transferase family 21
PICBCKBE_03218	5.73e-143	-	-	-	I	-	-	-	Belongs to the PlsY family
PICBCKBE_03219	3.79e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PICBCKBE_03220	4.41e-113	-	-	-	C	-	-	-	Flavodoxin
PICBCKBE_03221	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PICBCKBE_03223	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03224	2.49e-43	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
PICBCKBE_03225	0.0	-	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PICBCKBE_03226	1.44e-177	-	-	-	T	ko:K21562	-	ko00000,ko03000	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PICBCKBE_03227	3.57e-261	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PICBCKBE_03228	2.61e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PICBCKBE_03230	4.09e-219	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
PICBCKBE_03231	6.36e-162	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
PICBCKBE_03232	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PICBCKBE_03234	3.68e-295	-	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
PICBCKBE_03235	3.03e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
PICBCKBE_03236	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
PICBCKBE_03237	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PICBCKBE_03238	2.29e-107	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
PICBCKBE_03239	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PICBCKBE_03240	1.75e-228	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PICBCKBE_03241	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03242	6.38e-203	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_03243	4.06e-69	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_03244	8.41e-235	-	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PICBCKBE_03245	7.5e-100	-	-	-	-	-	-	-	-
PICBCKBE_03246	3.09e-59	-	-	-	S	-	-	-	DsrE/DsrF-like family
PICBCKBE_03247	8.96e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PICBCKBE_03248	0.0	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0236
PICBCKBE_03249	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_03250	9.01e-11	-	-	-	-	-	-	-	-
PICBCKBE_03251	4.77e-165	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PICBCKBE_03252	5.73e-170	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PICBCKBE_03253	1.32e-97	yycN	-	-	K	-	-	-	FR47-like protein
PICBCKBE_03254	6.64e-297	lmrP	-	-	E	ko:K08152	-	ko00000,ko02000	Transmembrane secretion effector
PICBCKBE_03255	6.46e-150	-	-	-	E	-	-	-	lactoylglutathione lyase activity
PICBCKBE_03257	3.59e-63	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
PICBCKBE_03258	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_03259	3.12e-115	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PICBCKBE_03261	4.14e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PICBCKBE_03263	9.02e-277	-	-	-	G	-	-	-	Major Facilitator Superfamily
PICBCKBE_03265	8.81e-240	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PICBCKBE_03266	9.96e-69	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
PICBCKBE_03267	1.17e-271	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PICBCKBE_03269	5.81e-218	-	-	-	F	-	-	-	ATP-grasp domain
PICBCKBE_03270	7.34e-59	-	-	-	S	-	-	-	ATP-grasp domain
PICBCKBE_03271	9.57e-87	-	-	-	F	-	-	-	ATP-grasp domain
PICBCKBE_03272	1.33e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PICBCKBE_03273	5.64e-59	ltaA	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	L-allo-threonine aldolase activity
PICBCKBE_03274	1.32e-161	-	-	-	-	-	-	-	-
PICBCKBE_03275	2.47e-77	-	-	-	-	-	-	-	-
PICBCKBE_03276	1.58e-138	-	-	-	K	-	-	-	Transcriptional regulator
PICBCKBE_03277	1.22e-132	-	-	-	Q	-	-	-	Isochorismatase family
PICBCKBE_03278	0.0	-	-	-	EGP	-	-	-	Major facilitator superfamily
PICBCKBE_03279	7.93e-278	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PICBCKBE_03280	8.76e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
PICBCKBE_03281	2.37e-124	XK27_04830	-	-	S	-	-	-	Protein of unknown function (DUF1700)
PICBCKBE_03282	1.05e-153	-	-	-	S	-	-	-	Putative adhesin
PICBCKBE_03283	0.0	-	-	-	NT	ko:K03406,ko:K06595	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemoreceptor zinc-binding domain
PICBCKBE_03284	1.02e-178	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PICBCKBE_03285	5.07e-202	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
PICBCKBE_03286	1.38e-254	-	-	-	EGP	-	-	-	COG2814 Arabinose efflux permease
PICBCKBE_03287	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_03288	4.9e-93	-	-	-	S	-	-	-	Pfam:DUF1399
PICBCKBE_03289	1.93e-303	-	-	-	L	-	-	-	Transposase DDE domain group 1
PICBCKBE_03290	1.55e-274	-	-	-	G	-	-	-	Major facilitator Superfamily
PICBCKBE_03291	0.0	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_03292	1.16e-128	-	-	-	L	-	-	-	Domain of unknown function (DUF4277)
PICBCKBE_03293	3.13e-34	-	-	-	L	-	-	-	PFAM Transposase, IS4-like
PICBCKBE_03294	2.94e-106	-	-	-	S	-	-	-	cellulose binding
PICBCKBE_03295	1.01e-107	-	-	-	-	-	-	-	-
PICBCKBE_03296	3.43e-185	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PICBCKBE_03297	1.91e-123	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
PICBCKBE_03299	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PICBCKBE_03300	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PICBCKBE_03301	2.16e-283	ybbR	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_03302	6.33e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PICBCKBE_03303	3.34e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PICBCKBE_03304	6.53e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PICBCKBE_03306	1.27e-216	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
PICBCKBE_03307	6.55e-157	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PICBCKBE_03309	2.28e-16	-	-	-	S	-	-	-	Haemolysin XhlA
PICBCKBE_03310	1.27e-41	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PICBCKBE_03312	5.4e-08	-	-	-	-	-	-	-	-
PICBCKBE_03313	6.78e-28	-	-	-	-	-	-	-	-
PICBCKBE_03314	6.6e-104	-	-	-	S	-	-	-	Prophage endopeptidase tail
PICBCKBE_03315	1.09e-80	-	-	-	S	-	-	-	Phage tail protein
PICBCKBE_03316	7.92e-83	-	-	-	S	-	-	-	domain protein
PICBCKBE_03319	2.42e-59	-	-	-	-	-	-	-	-
PICBCKBE_03320	9.68e-39	-	-	-	-	-	-	-	-
PICBCKBE_03321	9.51e-32	-	-	-	-	-	-	-	-
PICBCKBE_03325	6.28e-102	-	-	-	-	-	-	-	-
PICBCKBE_03327	9.74e-148	-	-	-	-	-	-	-	-
PICBCKBE_03328	4.59e-314	-	-	-	K	-	-	-	cell adhesion
PICBCKBE_03329	8.69e-223	-	-	-	S	-	-	-	Terminase-like family
PICBCKBE_03330	2.22e-80	-	-	-	L	-	-	-	transposase activity
PICBCKBE_03332	7.18e-52	yqaQ	-	-	L	-	-	-	Transposase
PICBCKBE_03333	6.08e-05	-	-	-	-	-	-	-	-
PICBCKBE_03335	2.33e-91	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
PICBCKBE_03336	2.46e-22	-	-	-	-	-	-	-	-
PICBCKBE_03337	9.12e-60	-	-	-	V	-	-	-	N-6 DNA Methylase
PICBCKBE_03339	6.34e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
PICBCKBE_03340	8.69e-58	-	-	-	S	-	-	-	dUTPase
PICBCKBE_03343	3.83e-163	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PICBCKBE_03345	5.85e-39	-	-	-	-	-	-	-	-
PICBCKBE_03346	1.62e-157	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PICBCKBE_03347	3.52e-178	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
PICBCKBE_03354	1.49e-21	-	-	-	S	-	-	-	Helix-turn-helix domain
PICBCKBE_03355	1.5e-71	-	-	-	K	-	-	-	Phage antirepressor protein KilAC domain
PICBCKBE_03356	2e-20	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
PICBCKBE_03357	1.05e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PICBCKBE_03358	1.98e-39	-	-	-	S	-	-	-	Pfam:Peptidase_M78
PICBCKBE_03360	1.14e-23	-	-	-	S	-	-	-	membrane
PICBCKBE_03361	2.16e-88	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
PICBCKBE_03362	1.39e-163	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PICBCKBE_03372	1.39e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PICBCKBE_03373	2.95e-147	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PICBCKBE_03374	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PICBCKBE_03375	3.56e-259	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PICBCKBE_03376	1.21e-212	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PICBCKBE_03377	2.29e-180	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PICBCKBE_03378	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
PICBCKBE_03379	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
PICBCKBE_03380	2.21e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
PICBCKBE_03381	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
PICBCKBE_03382	4.77e-42	-	-	-	-	-	-	-	-
PICBCKBE_03383	4.31e-177	pdaB	-	-	G	-	-	-	xylanase chitin deacetylase
PICBCKBE_03384	4.06e-238	-	-	-	S	-	-	-	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
PICBCKBE_03386	4.13e-140	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
PICBCKBE_03387	4.54e-112	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
PICBCKBE_03388	5.43e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PICBCKBE_03389	2.59e-169	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
PICBCKBE_03390	1.73e-107	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
PICBCKBE_03391	0.0	lysP	-	-	E	ko:K11733	-	ko00000,ko02000	amino acid
PICBCKBE_03392	6.21e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
PICBCKBE_03393	9.55e-289	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
PICBCKBE_03395	0.0	-	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
PICBCKBE_03396	1.74e-124	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PICBCKBE_03397	9.65e-275	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PICBCKBE_03398	1.36e-28	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PICBCKBE_03399	1.05e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PICBCKBE_03400	3.24e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PICBCKBE_03401	5.67e-177	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PICBCKBE_03402	2.18e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PICBCKBE_03403	4.72e-207	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PICBCKBE_03404	8.45e-202	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PICBCKBE_03406	8.7e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PICBCKBE_03407	9.96e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PICBCKBE_03408	9.37e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PICBCKBE_03409	6.28e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PICBCKBE_03410	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PICBCKBE_03411	3.31e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PICBCKBE_03412	1.14e-292	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PICBCKBE_03413	3.48e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
PICBCKBE_03414	2.65e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PICBCKBE_03415	5.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PICBCKBE_03416	1.22e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PICBCKBE_03417	1.76e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PICBCKBE_03418	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PICBCKBE_03419	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PICBCKBE_03420	9.01e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PICBCKBE_03421	2.15e-75	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PICBCKBE_03422	1.48e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PICBCKBE_03423	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PICBCKBE_03424	2.44e-36	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PICBCKBE_03425	2.03e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PICBCKBE_03426	7.14e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PICBCKBE_03427	2.75e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PICBCKBE_03428	1.16e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PICBCKBE_03429	1.46e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PICBCKBE_03430	3.56e-57	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PICBCKBE_03431	8.08e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PICBCKBE_03432	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PICBCKBE_03433	1.82e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PICBCKBE_03434	8.83e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PICBCKBE_03435	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PICBCKBE_03436	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PICBCKBE_03437	2.06e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PICBCKBE_03438	5.27e-49	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
PICBCKBE_03439	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PICBCKBE_03440	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PICBCKBE_03441	5.13e-144	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PICBCKBE_03442	1.94e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PICBCKBE_03443	5.97e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PICBCKBE_03445	6.58e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PICBCKBE_03446	2.39e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PICBCKBE_03447	9.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PICBCKBE_03448	6.36e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PICBCKBE_03449	3.83e-147	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
PICBCKBE_03450	5.27e-117	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
PICBCKBE_03451	2.48e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PICBCKBE_03452	1.88e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PICBCKBE_03453	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PICBCKBE_03454	5.88e-154	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
PICBCKBE_03455	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PICBCKBE_03456	2.39e-108	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PICBCKBE_03457	1.01e-156	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PICBCKBE_03458	8.64e-253	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
PICBCKBE_03459	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PICBCKBE_03461	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
PICBCKBE_03462	7.06e-249	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PICBCKBE_03463	1.34e-132	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
PICBCKBE_03464	6.38e-97	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PICBCKBE_03466	7.37e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3969)
PICBCKBE_03467	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_03470	8.4e-51	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
PICBCKBE_03471	1.58e-11	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PICBCKBE_03472	4.93e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PICBCKBE_03473	1.28e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PICBCKBE_03474	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PICBCKBE_03475	1.78e-113	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PICBCKBE_03476	4.53e-246	-	-	-	L	-	-	-	COG3039 Transposase and inactivated derivatives, IS5 family
PICBCKBE_03477	5.75e-226	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03478	0.0	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
PICBCKBE_03479	6.43e-153	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
PICBCKBE_03480	2.42e-162	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
PICBCKBE_03482	1.44e-292	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PICBCKBE_03483	2.28e-133	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PICBCKBE_03484	9.82e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PICBCKBE_03485	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PICBCKBE_03486	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PICBCKBE_03487	3.29e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
PICBCKBE_03488	1.39e-58	-	-	-	-	-	-	-	-
PICBCKBE_03489	1.73e-57	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
PICBCKBE_03497	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PICBCKBE_03498	5.73e-125	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PICBCKBE_03499	2.39e-21	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PICBCKBE_03500	2.74e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PICBCKBE_03501	2.18e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PICBCKBE_03502	5.07e-204	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PICBCKBE_03503	9.15e-183	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PICBCKBE_03504	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PICBCKBE_03505	2.89e-123	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
PICBCKBE_03506	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PICBCKBE_03507	3.24e-225	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PICBCKBE_03508	1.72e-162	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
PICBCKBE_03509	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
PICBCKBE_03511	7.71e-85	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
PICBCKBE_03512	7.06e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PICBCKBE_03513	1.39e-141	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
PICBCKBE_03514	1.23e-67	yabP	-	-	S	-	-	-	Sporulation protein YabP
PICBCKBE_03515	1.58e-55	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PICBCKBE_03516	8.25e-249	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PICBCKBE_03517	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PICBCKBE_03518	2.8e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
PICBCKBE_03519	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PICBCKBE_03520	1.79e-50	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
PICBCKBE_03521	1.38e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PICBCKBE_03522	5.06e-144	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PICBCKBE_03523	1.32e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PICBCKBE_03524	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PICBCKBE_03525	2.07e-106	-	-	-	-	-	-	-	-
PICBCKBE_03526	9.05e-55	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Abc transporter
PICBCKBE_03527	2.95e-92	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PICBCKBE_03529	2.1e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PICBCKBE_03530	5.31e-82	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
PICBCKBE_03531	1.24e-198	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PICBCKBE_03532	6.21e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PICBCKBE_03533	4.78e-46	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
PICBCKBE_03534	8.34e-51	veg	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_03535	1.66e-213	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
PICBCKBE_03536	2.94e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PICBCKBE_03537	9.16e-138	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PICBCKBE_03538	4.68e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
PICBCKBE_03539	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PICBCKBE_03540	6.07e-77	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
PICBCKBE_03541	1.53e-210	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PICBCKBE_03542	2.98e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
PICBCKBE_03543	8.7e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
PICBCKBE_03544	1.06e-87	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PICBCKBE_03545	3.27e-191	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
PICBCKBE_03546	1.99e-237	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PICBCKBE_03547	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
PICBCKBE_03548	3.54e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
PICBCKBE_03549	2.41e-155	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PICBCKBE_03550	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
PICBCKBE_03551	6.44e-49	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
PICBCKBE_03552	4.29e-120	-	-	-	L	-	-	-	Transposase, Mutator family
PICBCKBE_03553	4.81e-252	M1-161	-	-	T	-	-	-	HD domain
PICBCKBE_03554	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PICBCKBE_03555	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PICBCKBE_03556	9.35e-16	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
PICBCKBE_03557	1.77e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PICBCKBE_03558	2.41e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
PICBCKBE_03559	9.58e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria