ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EKFEBFEA_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKFEBFEA_00002 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EKFEBFEA_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EKFEBFEA_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKFEBFEA_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
EKFEBFEA_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKFEBFEA_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKFEBFEA_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00011 4.5e-234 yaaC - - S - - - YaaC-like Protein
EKFEBFEA_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EKFEBFEA_00013 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EKFEBFEA_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EKFEBFEA_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EKFEBFEA_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKFEBFEA_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EKFEBFEA_00019 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EKFEBFEA_00020 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EKFEBFEA_00021 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EKFEBFEA_00022 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EKFEBFEA_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKFEBFEA_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKFEBFEA_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKFEBFEA_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
EKFEBFEA_00027 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EKFEBFEA_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EKFEBFEA_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EKFEBFEA_00033 5.05e-260 yaaN - - P - - - Belongs to the TelA family
EKFEBFEA_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EKFEBFEA_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKFEBFEA_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
EKFEBFEA_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EKFEBFEA_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EKFEBFEA_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
EKFEBFEA_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EKFEBFEA_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EKFEBFEA_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EKFEBFEA_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKFEBFEA_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EKFEBFEA_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKFEBFEA_00046 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EKFEBFEA_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
EKFEBFEA_00048 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKFEBFEA_00049 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKFEBFEA_00050 6.69e-200 yabG - - S ko:K06436 - ko00000 peptidase
EKFEBFEA_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
EKFEBFEA_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
EKFEBFEA_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKFEBFEA_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EKFEBFEA_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EKFEBFEA_00056 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EKFEBFEA_00057 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKFEBFEA_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKFEBFEA_00059 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EKFEBFEA_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EKFEBFEA_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
EKFEBFEA_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKFEBFEA_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EKFEBFEA_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EKFEBFEA_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EKFEBFEA_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
EKFEBFEA_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
EKFEBFEA_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EKFEBFEA_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EKFEBFEA_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EKFEBFEA_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EKFEBFEA_00075 1.25e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EKFEBFEA_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EKFEBFEA_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EKFEBFEA_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKFEBFEA_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EKFEBFEA_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKFEBFEA_00081 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EKFEBFEA_00082 3.77e-218 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EKFEBFEA_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKFEBFEA_00084 1.03e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EKFEBFEA_00085 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EKFEBFEA_00086 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EKFEBFEA_00087 2.78e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKFEBFEA_00088 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EKFEBFEA_00089 1.81e-41 yazB - - K - - - transcriptional
EKFEBFEA_00090 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKFEBFEA_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EKFEBFEA_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EKFEBFEA_00104 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EKFEBFEA_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EKFEBFEA_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EKFEBFEA_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKFEBFEA_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EKFEBFEA_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EKFEBFEA_00110 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EKFEBFEA_00111 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EKFEBFEA_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKFEBFEA_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EKFEBFEA_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EKFEBFEA_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKFEBFEA_00116 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKFEBFEA_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EKFEBFEA_00118 8.04e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EKFEBFEA_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EKFEBFEA_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EKFEBFEA_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKFEBFEA_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EKFEBFEA_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKFEBFEA_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EKFEBFEA_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EKFEBFEA_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFEBFEA_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFEBFEA_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EKFEBFEA_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKFEBFEA_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EKFEBFEA_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKFEBFEA_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKFEBFEA_00133 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
EKFEBFEA_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EKFEBFEA_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKFEBFEA_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EKFEBFEA_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EKFEBFEA_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKFEBFEA_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKFEBFEA_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKFEBFEA_00141 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKFEBFEA_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKFEBFEA_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EKFEBFEA_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKFEBFEA_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKFEBFEA_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKFEBFEA_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKFEBFEA_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKFEBFEA_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKFEBFEA_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKFEBFEA_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKFEBFEA_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKFEBFEA_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EKFEBFEA_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EKFEBFEA_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EKFEBFEA_00156 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EKFEBFEA_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EKFEBFEA_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKFEBFEA_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EKFEBFEA_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKFEBFEA_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKFEBFEA_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKFEBFEA_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EKFEBFEA_00164 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFEBFEA_00165 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFEBFEA_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKFEBFEA_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EKFEBFEA_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKFEBFEA_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EKFEBFEA_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
EKFEBFEA_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
EKFEBFEA_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EKFEBFEA_00173 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EKFEBFEA_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
EKFEBFEA_00175 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EKFEBFEA_00176 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
EKFEBFEA_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00186 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EKFEBFEA_00188 3.47e-205 ybaS - - S - - - Na -dependent transporter
EKFEBFEA_00189 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
EKFEBFEA_00190 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00191 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00192 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EKFEBFEA_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EKFEBFEA_00194 3.6e-306 ybbC - - S - - - protein conserved in bacteria
EKFEBFEA_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EKFEBFEA_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EKFEBFEA_00197 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00198 3.82e-194 ybbH - - K - - - transcriptional
EKFEBFEA_00199 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EKFEBFEA_00200 1.55e-114 ybbJ - - J - - - acetyltransferase
EKFEBFEA_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
EKFEBFEA_00207 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_00208 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EKFEBFEA_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKFEBFEA_00210 4.16e-292 ybbR - - S - - - protein conserved in bacteria
EKFEBFEA_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKFEBFEA_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EKFEBFEA_00213 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EKFEBFEA_00214 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EKFEBFEA_00215 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKFEBFEA_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EKFEBFEA_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
EKFEBFEA_00218 2.51e-125 ybcF - - P - - - carbonic anhydrase
EKFEBFEA_00219 5.59e-64 - - - - - - - -
EKFEBFEA_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
EKFEBFEA_00221 9.45e-67 - - - K - - - Helix-turn-helix domain
EKFEBFEA_00222 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
EKFEBFEA_00224 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
EKFEBFEA_00225 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
EKFEBFEA_00226 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EKFEBFEA_00227 3.99e-313 skfF - - S - - - ABC transporter
EKFEBFEA_00228 3.88e-118 - - - C - - - HEAT repeats
EKFEBFEA_00229 5.88e-103 - - - CO - - - Thioredoxin-like domain
EKFEBFEA_00230 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EKFEBFEA_00231 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
EKFEBFEA_00232 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
EKFEBFEA_00234 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
EKFEBFEA_00235 6.61e-196 ybdN - - - - - - -
EKFEBFEA_00236 1.19e-278 ybdO - - S - - - Domain of unknown function (DUF4885)
EKFEBFEA_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EKFEBFEA_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
EKFEBFEA_00240 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
EKFEBFEA_00241 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EKFEBFEA_00242 1.11e-54 ybyB - - - - - - -
EKFEBFEA_00243 0.0 ybeC - - E - - - amino acid
EKFEBFEA_00244 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EKFEBFEA_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EKFEBFEA_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
EKFEBFEA_00247 8.93e-220 ybfA - - K - - - FR47-like protein
EKFEBFEA_00248 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EKFEBFEA_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
EKFEBFEA_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
EKFEBFEA_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKFEBFEA_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
EKFEBFEA_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
EKFEBFEA_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKFEBFEA_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
EKFEBFEA_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EKFEBFEA_00260 2.33e-61 ybfN - - - - - - -
EKFEBFEA_00261 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
EKFEBFEA_00262 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_00263 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EKFEBFEA_00264 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFEBFEA_00265 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00266 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EKFEBFEA_00267 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EKFEBFEA_00269 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EKFEBFEA_00270 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EKFEBFEA_00271 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EKFEBFEA_00272 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EKFEBFEA_00273 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EKFEBFEA_00274 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_00275 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EKFEBFEA_00276 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
EKFEBFEA_00277 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFEBFEA_00278 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_00279 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EKFEBFEA_00280 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
EKFEBFEA_00281 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EKFEBFEA_00282 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EKFEBFEA_00283 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EKFEBFEA_00284 1.87e-220 eamA1 - - EG - - - spore germination
EKFEBFEA_00285 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_00286 1.66e-218 ycbM - - T - - - Histidine kinase
EKFEBFEA_00287 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00288 4.25e-150 - - - S - - - ABC-2 family transporter protein
EKFEBFEA_00289 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
EKFEBFEA_00290 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EKFEBFEA_00291 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
EKFEBFEA_00292 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EKFEBFEA_00293 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKFEBFEA_00294 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKFEBFEA_00295 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EKFEBFEA_00296 3.48e-268 ycbU - - E - - - Selenocysteine lyase
EKFEBFEA_00297 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EKFEBFEA_00298 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EKFEBFEA_00299 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EKFEBFEA_00300 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EKFEBFEA_00301 4.32e-78 - - - S - - - RDD family
EKFEBFEA_00302 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
EKFEBFEA_00303 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
EKFEBFEA_00304 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EKFEBFEA_00305 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EKFEBFEA_00306 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EKFEBFEA_00307 5.83e-223 yccK - - C - - - Aldo keto reductase
EKFEBFEA_00308 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
EKFEBFEA_00309 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_00310 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_00311 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EKFEBFEA_00312 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EKFEBFEA_00313 5.87e-181 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_00314 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EKFEBFEA_00315 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EKFEBFEA_00316 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EKFEBFEA_00317 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EKFEBFEA_00318 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_00319 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EKFEBFEA_00320 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EKFEBFEA_00321 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EKFEBFEA_00322 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EKFEBFEA_00323 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EKFEBFEA_00324 2.96e-245 yceH - - P - - - Belongs to the TelA family
EKFEBFEA_00325 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EKFEBFEA_00326 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
EKFEBFEA_00327 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EKFEBFEA_00328 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EKFEBFEA_00329 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EKFEBFEA_00330 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EKFEBFEA_00331 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EKFEBFEA_00332 0.0 ycgA - - S - - - Membrane
EKFEBFEA_00333 1.25e-127 ycgB - - - - - - -
EKFEBFEA_00334 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EKFEBFEA_00335 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EKFEBFEA_00336 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EKFEBFEA_00337 0.0 mdr - - EGP - - - the major facilitator superfamily
EKFEBFEA_00338 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_00339 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
EKFEBFEA_00340 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EKFEBFEA_00341 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_00342 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EKFEBFEA_00343 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EKFEBFEA_00344 1.31e-140 tmrB - - S - - - AAA domain
EKFEBFEA_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKFEBFEA_00346 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
EKFEBFEA_00347 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
EKFEBFEA_00348 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EKFEBFEA_00349 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EKFEBFEA_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EKFEBFEA_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKFEBFEA_00352 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFEBFEA_00353 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EKFEBFEA_00354 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
EKFEBFEA_00355 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
EKFEBFEA_00356 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
EKFEBFEA_00357 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EKFEBFEA_00358 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EKFEBFEA_00359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EKFEBFEA_00360 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EKFEBFEA_00361 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFEBFEA_00362 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EKFEBFEA_00363 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EKFEBFEA_00364 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
EKFEBFEA_00365 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
EKFEBFEA_00366 6.78e-291 yciC - - S - - - GTPases (G3E family)
EKFEBFEA_00367 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EKFEBFEA_00368 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EKFEBFEA_00371 5.95e-101 yckC - - S - - - membrane
EKFEBFEA_00372 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
EKFEBFEA_00373 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EKFEBFEA_00374 7.06e-93 nin - - S - - - Competence protein J (ComJ)
EKFEBFEA_00375 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
EKFEBFEA_00376 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_00377 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EKFEBFEA_00378 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EKFEBFEA_00379 6.05e-86 hxlR - - K - - - transcriptional
EKFEBFEA_00380 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_00381 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_00382 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EKFEBFEA_00383 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EKFEBFEA_00384 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
EKFEBFEA_00385 1.61e-126 - - - S - - - YcxB-like protein
EKFEBFEA_00386 1.77e-209 ycxC - - EG - - - EamA-like transporter family
EKFEBFEA_00387 0.0 ycxD - - K - - - GntR family transcriptional regulator
EKFEBFEA_00388 2.9e-96 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EKFEBFEA_00389 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
EKFEBFEA_00390 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EKFEBFEA_00391 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EKFEBFEA_00392 1.5e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EKFEBFEA_00393 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EKFEBFEA_00394 2.33e-142 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EKFEBFEA_00395 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EKFEBFEA_00396 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EKFEBFEA_00397 3.05e-109 yclD - - - - - - -
EKFEBFEA_00398 5.12e-207 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
EKFEBFEA_00399 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EKFEBFEA_00400 0.0 yclG - - M - - - Pectate lyase superfamily protein
EKFEBFEA_00402 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EKFEBFEA_00403 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
EKFEBFEA_00404 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EKFEBFEA_00405 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EKFEBFEA_00406 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EKFEBFEA_00407 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_00408 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EKFEBFEA_00409 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EKFEBFEA_00411 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EKFEBFEA_00412 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EKFEBFEA_00413 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00414 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00415 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00416 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EKFEBFEA_00417 0.0 ycnB - - EGP - - - the major facilitator superfamily
EKFEBFEA_00418 1.76e-199 ycnC - - K - - - Transcriptional regulator
EKFEBFEA_00419 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EKFEBFEA_00420 1.68e-60 ycnE - - S - - - Monooxygenase
EKFEBFEA_00421 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EKFEBFEA_00422 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_00423 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFEBFEA_00424 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFEBFEA_00425 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EKFEBFEA_00426 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_00427 1.07e-138 ycnI - - S - - - protein conserved in bacteria
EKFEBFEA_00428 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EKFEBFEA_00429 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EKFEBFEA_00430 1.34e-74 - - - - - - - -
EKFEBFEA_00431 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EKFEBFEA_00432 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EKFEBFEA_00433 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EKFEBFEA_00434 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EKFEBFEA_00436 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EKFEBFEA_00437 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
EKFEBFEA_00438 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EKFEBFEA_00440 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EKFEBFEA_00441 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EKFEBFEA_00442 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EKFEBFEA_00443 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EKFEBFEA_00444 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EKFEBFEA_00445 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EKFEBFEA_00446 3.8e-171 kipR - - K - - - Transcriptional regulator
EKFEBFEA_00447 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EKFEBFEA_00449 7.67e-66 yczJ - - S - - - biosynthesis
EKFEBFEA_00450 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EKFEBFEA_00451 3.26e-224 ycsN - - S - - - Oxidoreductase
EKFEBFEA_00452 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EKFEBFEA_00453 0.0 ydaB - - IQ - - - acyl-CoA ligase
EKFEBFEA_00454 6.05e-129 ydaC - - Q - - - Methyltransferase domain
EKFEBFEA_00455 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_00456 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EKFEBFEA_00457 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKFEBFEA_00458 5.24e-101 ydaG - - S - - - general stress protein
EKFEBFEA_00459 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EKFEBFEA_00460 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EKFEBFEA_00461 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EKFEBFEA_00462 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKFEBFEA_00463 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EKFEBFEA_00464 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EKFEBFEA_00465 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EKFEBFEA_00466 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
EKFEBFEA_00467 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EKFEBFEA_00468 0.0 ydaO - - E - - - amino acid
EKFEBFEA_00469 3.75e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EKFEBFEA_00470 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EKFEBFEA_00471 2.14e-53 - - - - - - - -
EKFEBFEA_00472 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EKFEBFEA_00473 1.67e-42 ydaS - - S - - - membrane
EKFEBFEA_00474 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EKFEBFEA_00475 1.06e-190 ydbA - - P - - - EcsC protein family
EKFEBFEA_00476 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
EKFEBFEA_00477 7.58e-79 ydbB - - G - - - Cupin domain
EKFEBFEA_00478 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
EKFEBFEA_00479 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
EKFEBFEA_00480 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EKFEBFEA_00481 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EKFEBFEA_00482 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EKFEBFEA_00483 4.43e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFEBFEA_00484 3.25e-231 ydbI - - S - - - AI-2E family transporter
EKFEBFEA_00485 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00486 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKFEBFEA_00487 9.32e-70 ydbL - - - - - - -
EKFEBFEA_00488 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
EKFEBFEA_00489 1.49e-26 - - - S - - - Fur-regulated basic protein B
EKFEBFEA_00491 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFEBFEA_00492 4.19e-75 ydbP - - CO - - - Thioredoxin
EKFEBFEA_00493 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EKFEBFEA_00494 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EKFEBFEA_00495 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKFEBFEA_00496 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EKFEBFEA_00497 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EKFEBFEA_00498 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EKFEBFEA_00499 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EKFEBFEA_00500 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EKFEBFEA_00501 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKFEBFEA_00502 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EKFEBFEA_00503 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EKFEBFEA_00504 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EKFEBFEA_00505 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EKFEBFEA_00506 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EKFEBFEA_00507 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EKFEBFEA_00508 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EKFEBFEA_00509 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EKFEBFEA_00510 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_00511 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EKFEBFEA_00515 1.32e-106 ydcG - - S - - - EVE domain
EKFEBFEA_00516 1.49e-40 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_00517 1.08e-43 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_00518 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EKFEBFEA_00519 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EKFEBFEA_00527 4.41e-270 ydcL - - L - - - Belongs to the 'phage' integrase family
EKFEBFEA_00528 1.41e-119 - - - E - - - IrrE N-terminal-like domain
EKFEBFEA_00529 1.91e-81 - - - K - - - Transcriptional
EKFEBFEA_00530 8.96e-24 - - - - - - - -
EKFEBFEA_00531 9.52e-56 - - - - - - - -
EKFEBFEA_00533 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
EKFEBFEA_00534 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
EKFEBFEA_00535 2.62e-263 nicK - - L ko:K07467 - ko00000 Replication initiation factor
EKFEBFEA_00538 1.38e-43 yddA - - - - - - -
EKFEBFEA_00539 7.65e-232 yddB - - S - - - Conjugative transposon protein TcpC
EKFEBFEA_00540 3.41e-54 yddC - - - - - - -
EKFEBFEA_00541 7.8e-124 yddD - - S - - - TcpE family
EKFEBFEA_00542 0.0 yddE - - S - - - AAA-like domain
EKFEBFEA_00543 2.81e-74 - - - S - - - Domain of unknown function (DUF1874)
EKFEBFEA_00544 0.0 yddG - - S - - - maturation of SSU-rRNA
EKFEBFEA_00545 4.74e-243 yddH - - M - - - Lysozyme-like
EKFEBFEA_00546 4.05e-114 yddI - - - - - - -
EKFEBFEA_00547 6.67e-86 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EKFEBFEA_00548 8.08e-192 - - - S - - - TIR domain
EKFEBFEA_00549 5.17e-92 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EKFEBFEA_00551 2.93e-212 - - - - - - - -
EKFEBFEA_00552 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_00553 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
EKFEBFEA_00554 2.17e-102 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
EKFEBFEA_00555 1.62e-128 yddQ - - Q - - - Isochorismatase family
EKFEBFEA_00556 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
EKFEBFEA_00557 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
EKFEBFEA_00562 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
EKFEBFEA_00563 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EKFEBFEA_00564 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EKFEBFEA_00565 2.47e-47 ydzE - - EG - - - spore germination
EKFEBFEA_00566 3.23e-215 - - - K - - - AraC-like ligand binding domain
EKFEBFEA_00567 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EKFEBFEA_00568 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EKFEBFEA_00569 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_00570 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
EKFEBFEA_00571 4.76e-72 ydeH - - - - - - -
EKFEBFEA_00572 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
EKFEBFEA_00573 6.11e-150 - - - - - - - -
EKFEBFEA_00574 4.66e-197 ydeK - - EG - - - -transporter
EKFEBFEA_00575 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_00576 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EKFEBFEA_00577 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
EKFEBFEA_00578 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
EKFEBFEA_00579 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EKFEBFEA_00580 5.03e-91 ydeP - - K - - - Transcriptional regulator
EKFEBFEA_00581 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
EKFEBFEA_00582 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EKFEBFEA_00583 3.74e-136 ydeS - - K - - - Transcriptional regulator
EKFEBFEA_00584 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EKFEBFEA_00585 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKFEBFEA_00586 8.05e-191 - - - J - - - GNAT acetyltransferase
EKFEBFEA_00587 3.05e-207 - - - EG - - - EamA-like transporter family
EKFEBFEA_00588 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_00589 5.97e-151 ydfE - - S - - - Flavin reductase like domain
EKFEBFEA_00590 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EKFEBFEA_00591 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKFEBFEA_00593 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_00594 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_00595 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EKFEBFEA_00596 9.73e-226 - - - S - - - Alpha/beta hydrolase family
EKFEBFEA_00597 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EKFEBFEA_00598 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
EKFEBFEA_00599 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFEBFEA_00600 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EKFEBFEA_00601 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EKFEBFEA_00602 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
EKFEBFEA_00603 9.63e-77 ydfQ - - CO - - - Thioredoxin
EKFEBFEA_00604 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
EKFEBFEA_00605 5.33e-39 - - - - - - - -
EKFEBFEA_00607 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
EKFEBFEA_00608 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
EKFEBFEA_00609 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EKFEBFEA_00610 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
EKFEBFEA_00611 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
EKFEBFEA_00612 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
EKFEBFEA_00613 4.21e-72 - - - S - - - DoxX-like family
EKFEBFEA_00614 2.49e-114 yycN - - K - - - Acetyltransferase
EKFEBFEA_00615 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EKFEBFEA_00616 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_00617 5.09e-119 - - - S - - - DinB family
EKFEBFEA_00618 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_00619 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EKFEBFEA_00620 6.42e-147 ydgI - - C - - - nitroreductase
EKFEBFEA_00621 1.15e-90 - - - K - - - Winged helix DNA-binding domain
EKFEBFEA_00622 5.97e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EKFEBFEA_00623 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EKFEBFEA_00624 5.24e-158 ydhC - - K - - - FCD
EKFEBFEA_00625 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
EKFEBFEA_00626 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKFEBFEA_00627 7.71e-166 - - - - - - - -
EKFEBFEA_00628 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EKFEBFEA_00629 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EKFEBFEA_00631 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
EKFEBFEA_00632 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EKFEBFEA_00633 4.01e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
EKFEBFEA_00634 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EKFEBFEA_00635 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00636 6.09e-70 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00637 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFEBFEA_00638 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EKFEBFEA_00639 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EKFEBFEA_00640 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EKFEBFEA_00641 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EKFEBFEA_00642 3.49e-273 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EKFEBFEA_00643 1.12e-98 ydhU - - P ko:K07217 - ko00000 Catalase
EKFEBFEA_00644 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
EKFEBFEA_00647 6.54e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00650 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EKFEBFEA_00651 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EKFEBFEA_00652 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EKFEBFEA_00653 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EKFEBFEA_00654 1.63e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKFEBFEA_00655 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EKFEBFEA_00656 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EKFEBFEA_00657 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKFEBFEA_00658 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EKFEBFEA_00659 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EKFEBFEA_00660 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EKFEBFEA_00661 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EKFEBFEA_00662 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKFEBFEA_00663 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EKFEBFEA_00665 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
EKFEBFEA_00666 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
EKFEBFEA_00667 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EKFEBFEA_00669 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
EKFEBFEA_00670 0.0 - - - J - - - LlaJI restriction endonuclease
EKFEBFEA_00671 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
EKFEBFEA_00672 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EKFEBFEA_00673 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EKFEBFEA_00674 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EKFEBFEA_00675 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EKFEBFEA_00676 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EKFEBFEA_00677 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKFEBFEA_00678 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EKFEBFEA_00679 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EKFEBFEA_00680 1.37e-248 - - - S - - - Ion transport 2 domain protein
EKFEBFEA_00681 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_00682 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EKFEBFEA_00683 1.79e-84 ydjM - - M - - - Lytic transglycolase
EKFEBFEA_00684 3.76e-213 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EKFEBFEA_00686 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
EKFEBFEA_00687 3.21e-205 - - - I - - - Alpha/beta hydrolase family
EKFEBFEA_00688 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
EKFEBFEA_00689 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EKFEBFEA_00690 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_00691 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKFEBFEA_00692 1.18e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EKFEBFEA_00693 6.74e-287 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EKFEBFEA_00694 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EKFEBFEA_00695 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EKFEBFEA_00696 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EKFEBFEA_00697 1.44e-165 yebC - - M - - - Membrane
EKFEBFEA_00699 2.66e-120 yebE - - S - - - UPF0316 protein
EKFEBFEA_00700 3.13e-38 yebG - - S - - - NETI protein
EKFEBFEA_00701 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKFEBFEA_00702 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKFEBFEA_00703 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKFEBFEA_00704 1.06e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EKFEBFEA_00705 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFEBFEA_00706 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFEBFEA_00707 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKFEBFEA_00708 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKFEBFEA_00709 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EKFEBFEA_00710 4.4e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKFEBFEA_00711 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EKFEBFEA_00712 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EKFEBFEA_00713 5.26e-96 - - - K - - - helix_turn_helix ASNC type
EKFEBFEA_00714 1.91e-297 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
EKFEBFEA_00715 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
EKFEBFEA_00716 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EKFEBFEA_00717 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EKFEBFEA_00718 7.62e-68 yerC - - S - - - protein conserved in bacteria
EKFEBFEA_00719 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EKFEBFEA_00721 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EKFEBFEA_00722 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EKFEBFEA_00723 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKFEBFEA_00724 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EKFEBFEA_00725 6.28e-253 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EKFEBFEA_00726 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EKFEBFEA_00727 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFEBFEA_00728 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKFEBFEA_00729 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EKFEBFEA_00730 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKFEBFEA_00731 2.93e-201 yerO - - K - - - Transcriptional regulator
EKFEBFEA_00732 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EKFEBFEA_00733 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKFEBFEA_00734 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKFEBFEA_00735 3.63e-127 - - - L - - - Recombinase
EKFEBFEA_00736 5.61e-71 - - - L - - - Resolvase, N terminal domain
EKFEBFEA_00737 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
EKFEBFEA_00738 0.0 - - - L - - - DEAD-like helicases superfamily
EKFEBFEA_00739 1.37e-271 yeeC - - P - - - T5orf172
EKFEBFEA_00740 7.48e-05 - - - - - - - -
EKFEBFEA_00741 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
EKFEBFEA_00742 2.1e-109 - - - S - - - Protein of unknown function, DUF600
EKFEBFEA_00743 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
EKFEBFEA_00744 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
EKFEBFEA_00745 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
EKFEBFEA_00747 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
EKFEBFEA_00749 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_00750 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
EKFEBFEA_00751 8.81e-206 yesF - - GM - - - NAD(P)H-binding
EKFEBFEA_00752 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EKFEBFEA_00753 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EKFEBFEA_00754 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EKFEBFEA_00755 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
EKFEBFEA_00757 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
EKFEBFEA_00758 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_00759 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
EKFEBFEA_00760 8.76e-316 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
EKFEBFEA_00761 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_00762 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_00763 6.85e-255 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
EKFEBFEA_00764 0.0 yesS - - K - - - Transcriptional regulator
EKFEBFEA_00765 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
EKFEBFEA_00766 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
EKFEBFEA_00767 3.44e-146 - - - S - - - Protein of unknown function, DUF624
EKFEBFEA_00768 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EKFEBFEA_00769 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EKFEBFEA_00770 6.37e-140 - - - E - - - GDSL-like Lipase/Acylhydrolase
EKFEBFEA_00771 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
EKFEBFEA_00772 0.0 yetA - - - - - - -
EKFEBFEA_00773 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EKFEBFEA_00774 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EKFEBFEA_00775 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_00776 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EKFEBFEA_00777 3.13e-158 yetF - - S - - - membrane
EKFEBFEA_00778 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EKFEBFEA_00779 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_00780 9.79e-45 - - - - - - - -
EKFEBFEA_00781 1.92e-57 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFEBFEA_00782 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFEBFEA_00783 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
EKFEBFEA_00784 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EKFEBFEA_00785 7.35e-203 - - - EG - - - EamA-like transporter family
EKFEBFEA_00786 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_00787 4.77e-270 yetM - - CH - - - FAD binding domain
EKFEBFEA_00788 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
EKFEBFEA_00789 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EKFEBFEA_00790 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EKFEBFEA_00791 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EKFEBFEA_00792 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EKFEBFEA_00793 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EKFEBFEA_00794 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
EKFEBFEA_00795 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EKFEBFEA_00796 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_00797 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EKFEBFEA_00798 4.16e-313 yfnA - - E ko:K03294 - ko00000 amino acid
EKFEBFEA_00799 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFEBFEA_00800 5.14e-161 yfmS - - NT - - - chemotaxis protein
EKFEBFEA_00801 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFEBFEA_00802 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EKFEBFEA_00803 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EKFEBFEA_00804 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EKFEBFEA_00805 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFEBFEA_00806 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EKFEBFEA_00807 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EKFEBFEA_00808 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EKFEBFEA_00809 1.72e-268 - - - G - - - Major Facilitator Superfamily
EKFEBFEA_00810 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
EKFEBFEA_00811 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EKFEBFEA_00812 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00813 2.85e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00814 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EKFEBFEA_00815 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
EKFEBFEA_00816 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
EKFEBFEA_00817 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EKFEBFEA_00818 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EKFEBFEA_00819 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EKFEBFEA_00820 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EKFEBFEA_00821 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EKFEBFEA_00823 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EKFEBFEA_00824 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EKFEBFEA_00825 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EKFEBFEA_00826 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EKFEBFEA_00827 2.51e-159 yflK - - S - - - protein conserved in bacteria
EKFEBFEA_00828 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
EKFEBFEA_00829 6.9e-27 yflI - - - - - - -
EKFEBFEA_00830 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
EKFEBFEA_00831 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EKFEBFEA_00832 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EKFEBFEA_00833 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EKFEBFEA_00834 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EKFEBFEA_00835 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
EKFEBFEA_00836 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
EKFEBFEA_00838 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
EKFEBFEA_00839 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EKFEBFEA_00840 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00841 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EKFEBFEA_00842 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EKFEBFEA_00843 5.27e-161 frp - - C - - - nitroreductase
EKFEBFEA_00844 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EKFEBFEA_00845 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EKFEBFEA_00846 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_00847 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
EKFEBFEA_00848 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKFEBFEA_00849 2.53e-67 yfkI - - S - - - gas vesicle protein
EKFEBFEA_00850 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EKFEBFEA_00851 1.64e-12 - - - - - - - -
EKFEBFEA_00852 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_00853 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EKFEBFEA_00854 3.69e-189 yfkD - - S - - - YfkD-like protein
EKFEBFEA_00855 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
EKFEBFEA_00856 1.76e-283 yfkA - - S - - - YfkB-like domain
EKFEBFEA_00857 3.26e-36 yfjT - - - - - - -
EKFEBFEA_00858 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EKFEBFEA_00859 4.82e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EKFEBFEA_00860 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EKFEBFEA_00861 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EKFEBFEA_00862 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKFEBFEA_00863 3e-53 - - - S - - - YfzA-like protein
EKFEBFEA_00864 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKFEBFEA_00865 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
EKFEBFEA_00867 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFEBFEA_00868 2.75e-244 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFEBFEA_00869 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFEBFEA_00870 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFEBFEA_00871 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EKFEBFEA_00872 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EKFEBFEA_00873 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
EKFEBFEA_00874 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
EKFEBFEA_00875 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
EKFEBFEA_00876 2.5e-185 yfjC - - - - - - -
EKFEBFEA_00877 1.94e-270 yfjB - - - - - - -
EKFEBFEA_00878 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
EKFEBFEA_00879 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKFEBFEA_00880 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EKFEBFEA_00881 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_00882 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EKFEBFEA_00883 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFEBFEA_00884 2.01e-84 yfiD3 - - S - - - DoxX
EKFEBFEA_00885 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EKFEBFEA_00886 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
EKFEBFEA_00887 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_00888 5.47e-234 - - - G - - - Xylose isomerase
EKFEBFEA_00889 5.17e-295 - - - S - - - Oxidoreductase
EKFEBFEA_00891 7.54e-276 baeS - - T - - - Histidine kinase
EKFEBFEA_00892 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EKFEBFEA_00893 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00894 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EKFEBFEA_00895 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EKFEBFEA_00896 1.89e-128 padR - - K - - - transcriptional
EKFEBFEA_00897 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EKFEBFEA_00898 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EKFEBFEA_00899 4.18e-141 yfiR - - K - - - Transcriptional regulator
EKFEBFEA_00900 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
EKFEBFEA_00901 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EKFEBFEA_00902 0.0 yfiU - - EGP - - - the major facilitator superfamily
EKFEBFEA_00903 5.39e-106 yfiV - - K - - - transcriptional
EKFEBFEA_00904 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKFEBFEA_00905 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EKFEBFEA_00906 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00907 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_00908 7.61e-215 yfhB - - S - - - PhzF family
EKFEBFEA_00909 2.87e-138 yfhC - - C - - - nitroreductase
EKFEBFEA_00910 8.86e-35 yfhD - - S - - - YfhD-like protein
EKFEBFEA_00912 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EKFEBFEA_00913 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EKFEBFEA_00914 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
EKFEBFEA_00916 2.45e-268 yfhI - - EGP - - - -transporter
EKFEBFEA_00917 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
EKFEBFEA_00918 8.95e-60 yfhJ - - S - - - WVELL protein
EKFEBFEA_00919 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
EKFEBFEA_00920 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
EKFEBFEA_00921 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
EKFEBFEA_00922 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_00923 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EKFEBFEA_00924 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EKFEBFEA_00925 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EKFEBFEA_00926 1.73e-48 yfhS - - - - - - -
EKFEBFEA_00927 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_00928 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EKFEBFEA_00929 2.01e-49 ygaB - - S - - - YgaB-like protein
EKFEBFEA_00930 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EKFEBFEA_00931 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EKFEBFEA_00932 1.87e-238 ygaE - - S - - - Membrane
EKFEBFEA_00933 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EKFEBFEA_00934 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EKFEBFEA_00935 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EKFEBFEA_00936 4.67e-75 ygzB - - S - - - UPF0295 protein
EKFEBFEA_00937 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
EKFEBFEA_00938 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_00956 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
EKFEBFEA_00957 3.88e-37 - - - - - - - -
EKFEBFEA_00958 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EKFEBFEA_00959 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EKFEBFEA_00960 0.0 ygaK - - C - - - Berberine and berberine like
EKFEBFEA_00962 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EKFEBFEA_00963 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EKFEBFEA_00964 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EKFEBFEA_00965 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EKFEBFEA_00966 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EKFEBFEA_00968 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKFEBFEA_00969 2.79e-102 ygaO - - - - - - -
EKFEBFEA_00970 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_00972 1.92e-147 yhzB - - S - - - B3/4 domain
EKFEBFEA_00973 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKFEBFEA_00974 4.79e-226 yhbB - - S - - - Putative amidase domain
EKFEBFEA_00975 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EKFEBFEA_00976 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
EKFEBFEA_00977 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EKFEBFEA_00978 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EKFEBFEA_00979 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EKFEBFEA_00980 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EKFEBFEA_00981 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EKFEBFEA_00982 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EKFEBFEA_00983 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EKFEBFEA_00984 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
EKFEBFEA_00985 3.95e-59 yhcC - - - - - - -
EKFEBFEA_00986 2.92e-69 - - - - - - - -
EKFEBFEA_00987 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_00988 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00989 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_00990 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKFEBFEA_00991 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EKFEBFEA_00992 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EKFEBFEA_00993 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EKFEBFEA_00994 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFEBFEA_00995 3.23e-80 yhcM - - - - - - -
EKFEBFEA_00996 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFEBFEA_00997 3.96e-227 yhcP - - - - - - -
EKFEBFEA_00998 1.68e-146 yhcQ - - M - - - Spore coat protein
EKFEBFEA_00999 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EKFEBFEA_01000 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EKFEBFEA_01001 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EKFEBFEA_01002 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
EKFEBFEA_01003 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
EKFEBFEA_01004 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
EKFEBFEA_01005 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKFEBFEA_01006 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFEBFEA_01007 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EKFEBFEA_01008 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EKFEBFEA_01009 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKFEBFEA_01010 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EKFEBFEA_01011 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EKFEBFEA_01012 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_01013 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_01014 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EKFEBFEA_01015 1.65e-51 yhdB - - S - - - YhdB-like protein
EKFEBFEA_01016 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
EKFEBFEA_01017 2.4e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EKFEBFEA_01018 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EKFEBFEA_01019 5.29e-307 ygxB - - M - - - Conserved TM helix
EKFEBFEA_01020 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EKFEBFEA_01021 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EKFEBFEA_01022 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EKFEBFEA_01023 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01024 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EKFEBFEA_01025 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_01026 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
EKFEBFEA_01027 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKFEBFEA_01028 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_01029 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_01030 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
EKFEBFEA_01031 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
EKFEBFEA_01032 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_01033 6.74e-244 yhdN - - C - - - Aldo keto reductase
EKFEBFEA_01034 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKFEBFEA_01035 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EKFEBFEA_01036 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EKFEBFEA_01037 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EKFEBFEA_01038 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EKFEBFEA_01039 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKFEBFEA_01040 1.01e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKFEBFEA_01041 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EKFEBFEA_01042 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
EKFEBFEA_01043 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EKFEBFEA_01044 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EKFEBFEA_01045 5.7e-200 nodB1 - - G - - - deacetylase
EKFEBFEA_01046 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EKFEBFEA_01047 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EKFEBFEA_01048 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
EKFEBFEA_01049 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFEBFEA_01050 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFEBFEA_01051 3.31e-143 yheG - - GM - - - NAD(P)H-binding
EKFEBFEA_01052 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EKFEBFEA_01053 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
EKFEBFEA_01054 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EKFEBFEA_01055 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
EKFEBFEA_01056 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
EKFEBFEA_01057 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
EKFEBFEA_01058 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
EKFEBFEA_01059 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EKFEBFEA_01060 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EKFEBFEA_01061 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EKFEBFEA_01062 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EKFEBFEA_01064 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
EKFEBFEA_01065 2.29e-36 - - - S - - - YhzD-like protein
EKFEBFEA_01066 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_01067 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EKFEBFEA_01068 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EKFEBFEA_01069 0.0 yhaN - - L - - - AAA domain
EKFEBFEA_01070 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EKFEBFEA_01071 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
EKFEBFEA_01072 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EKFEBFEA_01073 1.4e-116 yhaK - - S - - - Putative zincin peptidase
EKFEBFEA_01074 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
EKFEBFEA_01075 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EKFEBFEA_01076 1.74e-54 yhaH - - S - - - YtxH-like protein
EKFEBFEA_01077 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
EKFEBFEA_01078 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKFEBFEA_01079 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EKFEBFEA_01080 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EKFEBFEA_01081 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EKFEBFEA_01082 5e-162 ecsC - - S - - - EcsC protein family
EKFEBFEA_01083 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EKFEBFEA_01084 8.98e-317 yhfA - - C - - - membrane
EKFEBFEA_01085 1.58e-12 - - - C - - - Rubrerythrin
EKFEBFEA_01086 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EKFEBFEA_01087 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EKFEBFEA_01088 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EKFEBFEA_01089 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EKFEBFEA_01090 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EKFEBFEA_01091 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01092 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EKFEBFEA_01093 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKFEBFEA_01094 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
EKFEBFEA_01095 2.68e-253 yhfE - - G - - - peptidase M42
EKFEBFEA_01096 3.75e-94 - - - S - - - ASCH
EKFEBFEA_01097 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKFEBFEA_01098 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EKFEBFEA_01099 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EKFEBFEA_01100 1.82e-144 yhfK - - GM - - - NmrA-like family
EKFEBFEA_01101 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EKFEBFEA_01102 2.78e-85 yhfM - - - - - - -
EKFEBFEA_01103 9.64e-308 yhfN - - O - - - Peptidase M48
EKFEBFEA_01104 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EKFEBFEA_01105 2.75e-105 - - - K - - - acetyltransferase
EKFEBFEA_01106 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EKFEBFEA_01107 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EKFEBFEA_01108 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EKFEBFEA_01109 1.19e-256 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EKFEBFEA_01110 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EKFEBFEA_01111 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EKFEBFEA_01112 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EKFEBFEA_01113 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EKFEBFEA_01114 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_01115 9.84e-45 yhzC - - S - - - IDEAL
EKFEBFEA_01116 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EKFEBFEA_01117 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_01118 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
EKFEBFEA_01119 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFEBFEA_01120 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
EKFEBFEA_01121 2.57e-78 yhjD - - - - - - -
EKFEBFEA_01122 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
EKFEBFEA_01123 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EKFEBFEA_01124 0.0 yhjG - - CH - - - FAD binding domain
EKFEBFEA_01125 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_01126 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EKFEBFEA_01127 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EKFEBFEA_01128 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
EKFEBFEA_01129 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EKFEBFEA_01130 2.63e-240 yhjM - - K - - - Transcriptional regulator
EKFEBFEA_01131 2.14e-260 yhjN - - S ko:K07120 - ko00000 membrane
EKFEBFEA_01132 1.27e-272 - - - EGP - - - Transmembrane secretion effector
EKFEBFEA_01133 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
EKFEBFEA_01134 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
EKFEBFEA_01135 9.3e-102 yhjR - - S - - - Rubrerythrin
EKFEBFEA_01136 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EKFEBFEA_01137 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EKFEBFEA_01138 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EKFEBFEA_01139 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EKFEBFEA_01140 1.34e-66 yisB - - V - - - COG1403 Restriction endonuclease
EKFEBFEA_01141 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EKFEBFEA_01142 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EKFEBFEA_01143 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EKFEBFEA_01144 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EKFEBFEA_01145 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
EKFEBFEA_01146 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EKFEBFEA_01147 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
EKFEBFEA_01148 3.96e-224 cotH - - M ko:K06330 - ko00000 Spore Coat
EKFEBFEA_01149 4.53e-13 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EKFEBFEA_01150 6.29e-162 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EKFEBFEA_01151 1.02e-74 yisL - - S - - - UPF0344 protein
EKFEBFEA_01152 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EKFEBFEA_01153 7.48e-137 yisN - - S - - - Protein of unknown function (DUF2777)
EKFEBFEA_01154 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EKFEBFEA_01155 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
EKFEBFEA_01156 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EKFEBFEA_01157 5.86e-310 yisQ - - V - - - Mate efflux family protein
EKFEBFEA_01158 1.72e-208 yisR - - K - - - Transcriptional regulator
EKFEBFEA_01159 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EKFEBFEA_01160 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EKFEBFEA_01161 7.28e-122 yisT - - S - - - DinB family
EKFEBFEA_01162 5.42e-140 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EKFEBFEA_01163 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EKFEBFEA_01164 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
EKFEBFEA_01165 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EKFEBFEA_01166 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EKFEBFEA_01167 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EKFEBFEA_01168 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EKFEBFEA_01169 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
EKFEBFEA_01170 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
EKFEBFEA_01171 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKFEBFEA_01172 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EKFEBFEA_01173 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_01174 7.86e-207 yitH - - K - - - Acetyltransferase (GNAT) domain
EKFEBFEA_01175 8.19e-107 - - - S - - - Acetyltransferase (GNAT) domain
EKFEBFEA_01176 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EKFEBFEA_01177 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EKFEBFEA_01178 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EKFEBFEA_01179 4.16e-122 - - - - - - - -
EKFEBFEA_01180 1.42e-218 - - - - - - - -
EKFEBFEA_01181 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
EKFEBFEA_01182 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
EKFEBFEA_01183 7.76e-123 - - - - - - - -
EKFEBFEA_01184 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
EKFEBFEA_01185 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EKFEBFEA_01186 9.13e-202 yitS - - S - - - protein conserved in bacteria
EKFEBFEA_01187 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EKFEBFEA_01188 1.61e-92 ipi - - S - - - Intracellular proteinase inhibitor
EKFEBFEA_01189 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
EKFEBFEA_01190 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EKFEBFEA_01191 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EKFEBFEA_01192 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EKFEBFEA_01193 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
EKFEBFEA_01194 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EKFEBFEA_01195 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
EKFEBFEA_01196 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKFEBFEA_01197 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKFEBFEA_01198 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EKFEBFEA_01199 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EKFEBFEA_01200 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EKFEBFEA_01201 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EKFEBFEA_01202 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKFEBFEA_01203 2.51e-39 yjzC - - S - - - YjzC-like protein
EKFEBFEA_01204 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
EKFEBFEA_01205 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
EKFEBFEA_01206 5.41e-134 yjaV - - - - - - -
EKFEBFEA_01207 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EKFEBFEA_01208 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EKFEBFEA_01209 2.67e-38 yjzB - - - - - - -
EKFEBFEA_01210 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKFEBFEA_01211 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKFEBFEA_01212 9.48e-193 yjaZ - - O - - - Zn-dependent protease
EKFEBFEA_01213 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01214 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01215 2.12e-77 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EKFEBFEA_01216 1.89e-239 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EKFEBFEA_01217 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01218 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01219 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
EKFEBFEA_01220 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EKFEBFEA_01221 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EKFEBFEA_01222 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01223 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01224 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01225 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01226 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
EKFEBFEA_01227 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_01228 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EKFEBFEA_01229 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
EKFEBFEA_01230 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKFEBFEA_01231 1.31e-283 coiA - - S ko:K06198 - ko00000 Competence protein
EKFEBFEA_01232 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EKFEBFEA_01233 2.68e-28 - - - - - - - -
EKFEBFEA_01235 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EKFEBFEA_01236 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EKFEBFEA_01237 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKFEBFEA_01238 5.15e-130 yjbK - - S - - - protein conserved in bacteria
EKFEBFEA_01239 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
EKFEBFEA_01240 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EKFEBFEA_01241 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKFEBFEA_01242 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EKFEBFEA_01243 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EKFEBFEA_01244 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKFEBFEA_01245 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EKFEBFEA_01246 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EKFEBFEA_01247 1.14e-277 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EKFEBFEA_01248 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
EKFEBFEA_01249 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EKFEBFEA_01250 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKFEBFEA_01251 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EKFEBFEA_01252 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EKFEBFEA_01253 2.32e-107 yjbX - - S - - - Spore coat protein
EKFEBFEA_01254 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EKFEBFEA_01255 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EKFEBFEA_01256 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EKFEBFEA_01257 1.08e-54 cotW - - - ko:K06341 - ko00000 -
EKFEBFEA_01258 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EKFEBFEA_01259 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
EKFEBFEA_01262 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
EKFEBFEA_01263 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EKFEBFEA_01264 6.31e-51 - - - - - - - -
EKFEBFEA_01265 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_01266 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EKFEBFEA_01267 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EKFEBFEA_01268 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EKFEBFEA_01269 6.4e-281 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EKFEBFEA_01270 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EKFEBFEA_01271 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
EKFEBFEA_01274 3.75e-269 - - - S - - - Putative amidase domain
EKFEBFEA_01275 1.52e-68 yjcN - - - - - - -
EKFEBFEA_01278 2.24e-106 - - - L - - - Transposase
EKFEBFEA_01279 5.68e-100 yjcP - - - - - - -
EKFEBFEA_01280 1.01e-65 - - - S - - - YjcQ protein
EKFEBFEA_01281 3.29e-121 yqaS - - L - - - DNA packaging
EKFEBFEA_01282 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EKFEBFEA_01283 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_01284 0.000759 - - - - - - - -
EKFEBFEA_01285 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EKFEBFEA_01286 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_01287 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EKFEBFEA_01288 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EKFEBFEA_01289 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EKFEBFEA_01291 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKFEBFEA_01292 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
EKFEBFEA_01293 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
EKFEBFEA_01294 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKFEBFEA_01296 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EKFEBFEA_01297 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
EKFEBFEA_01298 1.95e-30 yjfB - - S - - - Putative motility protein
EKFEBFEA_01299 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EKFEBFEA_01300 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
EKFEBFEA_01301 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
EKFEBFEA_01302 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EKFEBFEA_01303 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
EKFEBFEA_01305 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EKFEBFEA_01307 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EKFEBFEA_01308 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EKFEBFEA_01309 1.11e-41 - - - - - - - -
EKFEBFEA_01310 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EKFEBFEA_01311 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EKFEBFEA_01312 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EKFEBFEA_01313 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EKFEBFEA_01314 8.91e-121 yjlB - - S - - - Cupin domain
EKFEBFEA_01315 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EKFEBFEA_01316 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EKFEBFEA_01317 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EKFEBFEA_01318 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
EKFEBFEA_01319 2.02e-248 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
EKFEBFEA_01320 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EKFEBFEA_01321 1.66e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EKFEBFEA_01322 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_01323 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
EKFEBFEA_01324 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EKFEBFEA_01325 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EKFEBFEA_01326 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EKFEBFEA_01327 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EKFEBFEA_01328 4.87e-106 yjoA - - S - - - DinB family
EKFEBFEA_01329 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
EKFEBFEA_01330 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EKFEBFEA_01332 1.79e-55 - - - S - - - YCII-related domain
EKFEBFEA_01333 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EKFEBFEA_01334 3.31e-81 yjqA - - S - - - Bacterial PH domain
EKFEBFEA_01335 1.47e-143 yjqB - - S - - - Pfam:DUF867
EKFEBFEA_01336 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
EKFEBFEA_01337 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
EKFEBFEA_01338 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
EKFEBFEA_01340 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
EKFEBFEA_01341 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
EKFEBFEA_01345 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EKFEBFEA_01346 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EKFEBFEA_01347 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EKFEBFEA_01348 0.0 yqbA - - S - - - portal protein
EKFEBFEA_01349 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
EKFEBFEA_01350 3.91e-217 xkdG - - S - - - Phage capsid family
EKFEBFEA_01351 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
EKFEBFEA_01352 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
EKFEBFEA_01353 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EKFEBFEA_01354 2.87e-101 xkdJ - - - - - - -
EKFEBFEA_01355 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EKFEBFEA_01356 6.01e-99 xkdM - - S - - - Phage tail tube protein
EKFEBFEA_01357 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EKFEBFEA_01358 0.0 xkdO - - L - - - Transglycosylase SLT domain
EKFEBFEA_01359 1.77e-158 xkdP - - S - - - Lysin motif
EKFEBFEA_01360 2.31e-232 xkdQ - - G - - - NLP P60 protein
EKFEBFEA_01361 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
EKFEBFEA_01362 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
EKFEBFEA_01363 9.24e-246 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EKFEBFEA_01364 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EKFEBFEA_01365 4.43e-56 - - - - - - - -
EKFEBFEA_01366 0.0 - - - - - - - -
EKFEBFEA_01367 8.68e-74 xkdW - - S - - - XkdW protein
EKFEBFEA_01368 9.34e-33 xkdX - - - - - - -
EKFEBFEA_01369 1.51e-198 xepA - - - - - - -
EKFEBFEA_01370 7.71e-52 xhlA - - S - - - Haemolysin XhlA
EKFEBFEA_01371 8.12e-53 xhlB - - S - - - SPP1 phage holin
EKFEBFEA_01372 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EKFEBFEA_01373 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EKFEBFEA_01374 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EKFEBFEA_01375 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
EKFEBFEA_01376 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EKFEBFEA_01377 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
EKFEBFEA_01378 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EKFEBFEA_01380 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKFEBFEA_01381 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_01383 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFEBFEA_01384 1.54e-183 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
EKFEBFEA_01385 2.42e-197 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EKFEBFEA_01386 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01387 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKFEBFEA_01388 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01389 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EKFEBFEA_01391 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EKFEBFEA_01392 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EKFEBFEA_01393 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKFEBFEA_01394 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_01395 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EKFEBFEA_01396 4.37e-206 ykgA - - E - - - Amidinotransferase
EKFEBFEA_01397 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
EKFEBFEA_01398 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EKFEBFEA_01399 5.85e-13 - - - - - - - -
EKFEBFEA_01400 4.81e-168 ykjA - - S - - - Protein of unknown function (DUF421)
EKFEBFEA_01401 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
EKFEBFEA_01402 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKFEBFEA_01403 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EKFEBFEA_01404 2.86e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EKFEBFEA_01405 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EKFEBFEA_01406 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKFEBFEA_01407 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKFEBFEA_01408 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
EKFEBFEA_01409 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
EKFEBFEA_01410 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
EKFEBFEA_01412 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
EKFEBFEA_01413 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EKFEBFEA_01414 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EKFEBFEA_01415 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFEBFEA_01416 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EKFEBFEA_01417 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_01418 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EKFEBFEA_01419 7.28e-144 ykoF - - S - - - YKOF-related Family
EKFEBFEA_01420 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_01421 8.05e-312 ykoH - - T - - - Histidine kinase
EKFEBFEA_01422 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
EKFEBFEA_01423 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
EKFEBFEA_01424 1.45e-08 - - - - - - - -
EKFEBFEA_01426 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EKFEBFEA_01427 1.49e-70 tnrA - - K - - - transcriptional
EKFEBFEA_01428 1.63e-25 - - - - - - - -
EKFEBFEA_01429 3.04e-36 ykoL - - - - - - -
EKFEBFEA_01430 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EKFEBFEA_01431 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EKFEBFEA_01432 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
EKFEBFEA_01433 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EKFEBFEA_01434 0.0 ykoS - - - - - - -
EKFEBFEA_01435 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_01436 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EKFEBFEA_01437 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EKFEBFEA_01438 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
EKFEBFEA_01439 4.48e-153 ykoX - - S - - - membrane-associated protein
EKFEBFEA_01440 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EKFEBFEA_01441 1.47e-166 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_01442 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
EKFEBFEA_01443 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EKFEBFEA_01444 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
EKFEBFEA_01445 3.4e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EKFEBFEA_01446 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EKFEBFEA_01448 8.33e-31 ykzE - - - - - - -
EKFEBFEA_01449 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EKFEBFEA_01450 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_01451 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKFEBFEA_01453 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EKFEBFEA_01454 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EKFEBFEA_01455 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EKFEBFEA_01456 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EKFEBFEA_01457 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EKFEBFEA_01458 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EKFEBFEA_01459 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EKFEBFEA_01460 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EKFEBFEA_01461 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
EKFEBFEA_01463 5.84e-95 eag - - - - - - -
EKFEBFEA_01464 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EKFEBFEA_01465 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EKFEBFEA_01466 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EKFEBFEA_01467 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EKFEBFEA_01468 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EKFEBFEA_01469 4.26e-230 ykvI - - S - - - membrane
EKFEBFEA_01470 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EKFEBFEA_01471 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EKFEBFEA_01472 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EKFEBFEA_01473 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EKFEBFEA_01474 2.8e-81 ykvN - - K - - - Transcriptional regulator
EKFEBFEA_01475 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_01476 2.69e-275 - - - M - - - Glycosyl transferases group 1
EKFEBFEA_01477 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
EKFEBFEA_01478 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
EKFEBFEA_01479 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
EKFEBFEA_01480 5.43e-35 ykvS - - S - - - protein conserved in bacteria
EKFEBFEA_01481 2.6e-39 - - - - - - - -
EKFEBFEA_01482 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EKFEBFEA_01483 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_01484 5.79e-117 stoA - - CO - - - thiol-disulfide
EKFEBFEA_01485 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EKFEBFEA_01486 3.99e-09 - - - - - - - -
EKFEBFEA_01487 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EKFEBFEA_01489 3.28e-230 ykvZ - - K - - - Transcriptional regulator
EKFEBFEA_01491 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EKFEBFEA_01492 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_01493 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EKFEBFEA_01494 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKFEBFEA_01495 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01496 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EKFEBFEA_01497 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_01498 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_01499 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EKFEBFEA_01500 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
EKFEBFEA_01501 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EKFEBFEA_01502 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_01503 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EKFEBFEA_01504 1.05e-22 - - - - - - - -
EKFEBFEA_01505 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EKFEBFEA_01506 3.71e-110 ykyB - - S - - - YkyB-like protein
EKFEBFEA_01507 1.6e-69 - - - S - - - Bacterial protein of unknown function (DUF961)
EKFEBFEA_01508 1.39e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
EKFEBFEA_01509 0.0 - - - D ko:K03466 - ko00000,ko03036 Domain of unknown function DUF87
EKFEBFEA_01510 1.82e-297 - - - K ko:K07467 - ko00000 Replication initiation factor
EKFEBFEA_01511 3.41e-41 - - - S - - - Psort location CytoplasmicMembrane, score
EKFEBFEA_01512 1.42e-117 - - - S - - - Antirestriction protein (ArdA)
EKFEBFEA_01513 2.03e-88 - - - S - - - TcpE family
EKFEBFEA_01514 0.0 - - - S - - - AAA-like domain
EKFEBFEA_01515 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
EKFEBFEA_01516 3.21e-243 - - - M - - - NlpC p60 family protein
EKFEBFEA_01517 7.95e-221 - - - S - - - Conjugative transposon protein TcpC
EKFEBFEA_01518 0.0 - - - J - - - Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKFEBFEA_01519 8.07e-76 - - - K - - - Helix-turn-helix domain
EKFEBFEA_01520 3.84e-94 - - - K - - - Sigma-70, region 4
EKFEBFEA_01521 1.4e-48 - - - S - - - Helix-turn-helix domain
EKFEBFEA_01522 3.87e-42 xis - - S - - - Excisionase from transposon Tn916
EKFEBFEA_01523 1.68e-295 - - - L - - - DNA binding domain of tn916 integrase
EKFEBFEA_01524 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_01525 7.1e-116 ykuD - - S - - - protein conserved in bacteria
EKFEBFEA_01526 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EKFEBFEA_01527 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_01528 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
EKFEBFEA_01529 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
EKFEBFEA_01531 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
EKFEBFEA_01532 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
EKFEBFEA_01533 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
EKFEBFEA_01534 7.83e-38 ykzF - - S - - - Antirepressor AbbA
EKFEBFEA_01535 5.15e-100 ykuL - - S - - - CBS domain
EKFEBFEA_01536 6.52e-216 ccpC - - K - - - Transcriptional regulator
EKFEBFEA_01537 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
EKFEBFEA_01538 1.33e-226 ykuO - - - - - - -
EKFEBFEA_01539 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
EKFEBFEA_01540 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EKFEBFEA_01541 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EKFEBFEA_01542 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
EKFEBFEA_01543 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EKFEBFEA_01544 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
EKFEBFEA_01545 6.25e-106 ykuV - - CO - - - thiol-disulfide
EKFEBFEA_01546 4.71e-122 rok - - K - - - Repressor of ComK
EKFEBFEA_01547 1.47e-201 yknT - - - ko:K06437 - ko00000 -
EKFEBFEA_01548 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EKFEBFEA_01549 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EKFEBFEA_01550 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EKFEBFEA_01551 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EKFEBFEA_01552 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EKFEBFEA_01553 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EKFEBFEA_01554 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFEBFEA_01555 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EKFEBFEA_01556 1.6e-151 yknW - - S - - - Yip1 domain
EKFEBFEA_01557 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKFEBFEA_01558 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_01559 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EKFEBFEA_01560 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01561 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EKFEBFEA_01562 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EKFEBFEA_01563 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EKFEBFEA_01564 5.43e-52 ykoA - - - - - - -
EKFEBFEA_01565 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EKFEBFEA_01566 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKFEBFEA_01567 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EKFEBFEA_01568 1.09e-18 - - - S - - - Uncharacterized protein YkpC
EKFEBFEA_01569 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EKFEBFEA_01570 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EKFEBFEA_01571 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EKFEBFEA_01572 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EKFEBFEA_01573 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EKFEBFEA_01574 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EKFEBFEA_01575 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKFEBFEA_01576 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
EKFEBFEA_01577 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
EKFEBFEA_01578 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKFEBFEA_01579 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EKFEBFEA_01580 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
EKFEBFEA_01581 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFEBFEA_01582 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFEBFEA_01583 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFEBFEA_01584 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFEBFEA_01585 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EKFEBFEA_01586 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EKFEBFEA_01587 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
EKFEBFEA_01588 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
EKFEBFEA_01589 4.48e-35 ykzI - - - - - - -
EKFEBFEA_01590 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EKFEBFEA_01591 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
EKFEBFEA_01592 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EKFEBFEA_01593 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EKFEBFEA_01594 0.0 ylaA - - - - - - -
EKFEBFEA_01595 1.44e-56 ylaB - - - - - - -
EKFEBFEA_01596 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_01598 1.74e-57 ylaE - - - - - - -
EKFEBFEA_01599 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
EKFEBFEA_01600 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EKFEBFEA_01601 4.4e-63 ylaH - - S - - - YlaH-like protein
EKFEBFEA_01602 8.92e-44 ylaI - - S - - - protein conserved in bacteria
EKFEBFEA_01603 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFEBFEA_01604 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EKFEBFEA_01605 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EKFEBFEA_01606 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EKFEBFEA_01607 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
EKFEBFEA_01608 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EKFEBFEA_01609 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EKFEBFEA_01610 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EKFEBFEA_01611 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EKFEBFEA_01612 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EKFEBFEA_01613 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKFEBFEA_01614 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EKFEBFEA_01615 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EKFEBFEA_01616 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EKFEBFEA_01617 1.61e-81 ylbA - - S - - - YugN-like family
EKFEBFEA_01618 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
EKFEBFEA_01619 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
EKFEBFEA_01620 3.24e-89 ylbD - - S - - - Putative coat protein
EKFEBFEA_01621 1.73e-48 ylbE - - S - - - YlbE-like protein
EKFEBFEA_01622 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
EKFEBFEA_01623 4.36e-52 ylbG - - S - - - UPF0298 protein
EKFEBFEA_01624 2.12e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EKFEBFEA_01625 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKFEBFEA_01626 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EKFEBFEA_01627 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EKFEBFEA_01628 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EKFEBFEA_01629 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
EKFEBFEA_01631 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EKFEBFEA_01632 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EKFEBFEA_01633 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EKFEBFEA_01634 3.26e-116 ylbP - - K - - - n-acetyltransferase
EKFEBFEA_01635 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKFEBFEA_01636 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EKFEBFEA_01637 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EKFEBFEA_01638 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EKFEBFEA_01639 3.42e-68 ftsL - - D - - - Essential cell division protein
EKFEBFEA_01640 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EKFEBFEA_01641 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EKFEBFEA_01642 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKFEBFEA_01643 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKFEBFEA_01644 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKFEBFEA_01645 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EKFEBFEA_01646 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKFEBFEA_01647 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EKFEBFEA_01648 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EKFEBFEA_01649 3.45e-146 ylxW - - S - - - protein conserved in bacteria
EKFEBFEA_01650 1.06e-132 ylxX - - S - - - protein conserved in bacteria
EKFEBFEA_01651 5.37e-76 sbp - - S - - - small basic protein
EKFEBFEA_01652 8.45e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKFEBFEA_01653 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKFEBFEA_01654 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EKFEBFEA_01655 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EKFEBFEA_01656 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_01657 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_01658 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EKFEBFEA_01659 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EKFEBFEA_01660 3.58e-51 ylmC - - S - - - sporulation protein
EKFEBFEA_01661 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EKFEBFEA_01662 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EKFEBFEA_01663 7.41e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EKFEBFEA_01664 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EKFEBFEA_01665 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
EKFEBFEA_01666 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EKFEBFEA_01667 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKFEBFEA_01668 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
EKFEBFEA_01669 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKFEBFEA_01670 1.68e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EKFEBFEA_01671 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKFEBFEA_01672 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EKFEBFEA_01673 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EKFEBFEA_01674 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EKFEBFEA_01675 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EKFEBFEA_01676 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EKFEBFEA_01677 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EKFEBFEA_01678 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EKFEBFEA_01679 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EKFEBFEA_01680 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKFEBFEA_01682 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EKFEBFEA_01683 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EKFEBFEA_01684 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EKFEBFEA_01685 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EKFEBFEA_01686 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EKFEBFEA_01687 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EKFEBFEA_01688 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EKFEBFEA_01689 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EKFEBFEA_01690 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EKFEBFEA_01691 8.41e-202 yloC - - S - - - stress-induced protein
EKFEBFEA_01692 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EKFEBFEA_01693 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EKFEBFEA_01694 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EKFEBFEA_01695 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKFEBFEA_01696 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKFEBFEA_01697 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKFEBFEA_01698 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKFEBFEA_01699 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKFEBFEA_01700 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EKFEBFEA_01701 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EKFEBFEA_01702 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EKFEBFEA_01703 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EKFEBFEA_01704 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EKFEBFEA_01705 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EKFEBFEA_01706 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EKFEBFEA_01707 3.65e-78 yloU - - S - - - protein conserved in bacteria
EKFEBFEA_01708 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EKFEBFEA_01709 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EKFEBFEA_01710 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EKFEBFEA_01711 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKFEBFEA_01712 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EKFEBFEA_01713 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EKFEBFEA_01714 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EKFEBFEA_01715 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EKFEBFEA_01716 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKFEBFEA_01717 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EKFEBFEA_01718 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EKFEBFEA_01719 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EKFEBFEA_01720 1.67e-114 - - - - - - - -
EKFEBFEA_01721 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKFEBFEA_01722 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKFEBFEA_01723 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EKFEBFEA_01724 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EKFEBFEA_01725 5.89e-81 ylqD - - S - - - YlqD protein
EKFEBFEA_01726 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKFEBFEA_01727 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EKFEBFEA_01728 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EKFEBFEA_01729 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKFEBFEA_01730 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKFEBFEA_01731 0.0 ylqG - - - - - - -
EKFEBFEA_01732 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EKFEBFEA_01733 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EKFEBFEA_01734 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EKFEBFEA_01735 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EKFEBFEA_01736 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKFEBFEA_01737 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKFEBFEA_01738 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EKFEBFEA_01739 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKFEBFEA_01740 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKFEBFEA_01741 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EKFEBFEA_01742 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EKFEBFEA_01743 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EKFEBFEA_01744 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EKFEBFEA_01745 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EKFEBFEA_01746 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFEBFEA_01747 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EKFEBFEA_01748 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EKFEBFEA_01749 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EKFEBFEA_01750 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
EKFEBFEA_01751 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EKFEBFEA_01752 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EKFEBFEA_01753 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EKFEBFEA_01754 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EKFEBFEA_01755 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFEBFEA_01756 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EKFEBFEA_01757 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EKFEBFEA_01758 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EKFEBFEA_01759 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EKFEBFEA_01760 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EKFEBFEA_01761 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EKFEBFEA_01762 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKFEBFEA_01763 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EKFEBFEA_01764 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EKFEBFEA_01765 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EKFEBFEA_01766 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EKFEBFEA_01767 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EKFEBFEA_01768 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EKFEBFEA_01769 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EKFEBFEA_01770 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EKFEBFEA_01771 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_01772 6.91e-101 ylxL - - - - - - -
EKFEBFEA_01773 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EKFEBFEA_01774 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKFEBFEA_01775 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EKFEBFEA_01776 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EKFEBFEA_01777 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKFEBFEA_01778 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EKFEBFEA_01779 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EKFEBFEA_01780 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EKFEBFEA_01781 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EKFEBFEA_01782 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKFEBFEA_01783 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EKFEBFEA_01784 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EKFEBFEA_01785 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EKFEBFEA_01786 6.16e-63 ylxQ - - J - - - ribosomal protein
EKFEBFEA_01787 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKFEBFEA_01788 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EKFEBFEA_01789 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKFEBFEA_01790 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKFEBFEA_01791 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EKFEBFEA_01792 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKFEBFEA_01793 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EKFEBFEA_01794 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EKFEBFEA_01795 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
EKFEBFEA_01796 1.53e-56 ymxH - - S - - - YlmC YmxH family
EKFEBFEA_01797 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EKFEBFEA_01798 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EKFEBFEA_01799 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKFEBFEA_01800 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EKFEBFEA_01801 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKFEBFEA_01802 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKFEBFEA_01803 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EKFEBFEA_01804 4.94e-44 - - - S - - - YlzJ-like protein
EKFEBFEA_01805 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EKFEBFEA_01806 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01807 5.97e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_01808 2.96e-302 albE - - S - - - Peptidase M16
EKFEBFEA_01809 2.37e-309 ymfH - - S - - - zinc protease
EKFEBFEA_01810 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EKFEBFEA_01811 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
EKFEBFEA_01812 1.02e-97 ymfK - - S - - - Protein of unknown function (DUF3388)
EKFEBFEA_01813 1.33e-67 ymfK - - S - - - Protein of unknown function (DUF3388)
EKFEBFEA_01814 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EKFEBFEA_01815 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKFEBFEA_01816 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EKFEBFEA_01817 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKFEBFEA_01818 8.43e-282 pbpX - - V - - - Beta-lactamase
EKFEBFEA_01819 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EKFEBFEA_01820 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EKFEBFEA_01821 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EKFEBFEA_01822 1.01e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EKFEBFEA_01823 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKFEBFEA_01824 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EKFEBFEA_01825 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EKFEBFEA_01826 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EKFEBFEA_01827 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKFEBFEA_01828 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKFEBFEA_01829 7.19e-93 - - - S - - - Regulatory protein YrvL
EKFEBFEA_01831 1.38e-127 ymcC - - S - - - Membrane
EKFEBFEA_01832 2.94e-141 pksA - - K - - - Transcriptional regulator
EKFEBFEA_01833 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EKFEBFEA_01834 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EKFEBFEA_01836 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EKFEBFEA_01837 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EKFEBFEA_01838 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EKFEBFEA_01839 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKFEBFEA_01840 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EKFEBFEA_01841 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EKFEBFEA_01842 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EKFEBFEA_01843 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EKFEBFEA_01844 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EKFEBFEA_01845 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EKFEBFEA_01846 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EKFEBFEA_01847 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EKFEBFEA_01848 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EKFEBFEA_01849 2.49e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EKFEBFEA_01850 2.8e-81 ymzB - - - - - - -
EKFEBFEA_01851 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
EKFEBFEA_01852 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EKFEBFEA_01853 3.96e-163 ymaC - - S - - - Replication protein
EKFEBFEA_01854 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EKFEBFEA_01855 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
EKFEBFEA_01856 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EKFEBFEA_01858 5.41e-76 ymaF - - S - - - YmaF family
EKFEBFEA_01859 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKFEBFEA_01860 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EKFEBFEA_01861 8.07e-32 - - - - - - - -
EKFEBFEA_01862 1.2e-30 ymzA - - - - - - -
EKFEBFEA_01863 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EKFEBFEA_01864 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFEBFEA_01865 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFEBFEA_01866 2.24e-141 - - - - - - - -
EKFEBFEA_01867 1.72e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EKFEBFEA_01868 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EKFEBFEA_01869 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKFEBFEA_01870 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EKFEBFEA_01871 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EKFEBFEA_01872 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EKFEBFEA_01873 2.95e-14 - - - - - - - -
EKFEBFEA_01874 2.61e-40 - - - - - - - -
EKFEBFEA_01875 7.13e-52 - - - - - - - -
EKFEBFEA_01876 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
EKFEBFEA_01877 1.97e-186 ynaC - - - - - - -
EKFEBFEA_01878 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
EKFEBFEA_01879 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
EKFEBFEA_01880 1.06e-80 ynaF - - - - - - -
EKFEBFEA_01883 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
EKFEBFEA_01884 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EKFEBFEA_01885 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EKFEBFEA_01886 3.15e-278 xylR - - GK - - - ROK family
EKFEBFEA_01887 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EKFEBFEA_01888 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EKFEBFEA_01889 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EKFEBFEA_01890 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_01891 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKFEBFEA_01892 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
EKFEBFEA_01893 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EKFEBFEA_01894 7.54e-22 - - - - - - - -
EKFEBFEA_01897 7.03e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKFEBFEA_01899 1.55e-172 - - - S - - - Domain of unknown function, YrpD
EKFEBFEA_01902 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
EKFEBFEA_01903 8.92e-96 - - - - - - - -
EKFEBFEA_01904 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EKFEBFEA_01907 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EKFEBFEA_01908 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
EKFEBFEA_01909 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
EKFEBFEA_01910 9.15e-199 yndG - - S - - - DoxX-like family
EKFEBFEA_01911 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
EKFEBFEA_01912 0.0 yndJ - - S - - - YndJ-like protein
EKFEBFEA_01914 1.68e-177 yndL - - S - - - Replication protein
EKFEBFEA_01915 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
EKFEBFEA_01916 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EKFEBFEA_01918 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKFEBFEA_01919 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EKFEBFEA_01920 3.97e-145 yneB - - L - - - resolvase
EKFEBFEA_01921 1.15e-43 ynzC - - S - - - UPF0291 protein
EKFEBFEA_01922 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EKFEBFEA_01923 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EKFEBFEA_01924 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EKFEBFEA_01925 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
EKFEBFEA_01926 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EKFEBFEA_01927 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EKFEBFEA_01928 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EKFEBFEA_01929 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
EKFEBFEA_01930 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
EKFEBFEA_01931 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EKFEBFEA_01932 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EKFEBFEA_01933 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EKFEBFEA_01934 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EKFEBFEA_01935 9.26e-10 - - - S - - - Fur-regulated basic protein B
EKFEBFEA_01937 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EKFEBFEA_01938 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EKFEBFEA_01939 1.63e-71 yneQ - - - - - - -
EKFEBFEA_01940 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
EKFEBFEA_01941 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EKFEBFEA_01942 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EKFEBFEA_01943 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKFEBFEA_01944 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKFEBFEA_01945 1.82e-18 - - - - - - - -
EKFEBFEA_01946 1.06e-75 ynfC - - - - - - -
EKFEBFEA_01947 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EKFEBFEA_01948 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EKFEBFEA_01950 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
EKFEBFEA_01951 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EKFEBFEA_01952 1.04e-104 yngA - - S - - - membrane
EKFEBFEA_01953 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EKFEBFEA_01954 2.01e-134 yngC - - S - - - membrane-associated protein
EKFEBFEA_01955 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
EKFEBFEA_01956 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKFEBFEA_01957 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EKFEBFEA_01958 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EKFEBFEA_01959 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EKFEBFEA_01960 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EKFEBFEA_01961 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKFEBFEA_01962 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EKFEBFEA_01963 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
EKFEBFEA_01964 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EKFEBFEA_01965 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
EKFEBFEA_01966 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
EKFEBFEA_01967 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_01968 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_01969 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_01970 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_01971 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EKFEBFEA_01972 2.54e-245 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EKFEBFEA_01973 9.8e-313 yoeA - - V - - - MATE efflux family protein
EKFEBFEA_01974 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EKFEBFEA_01976 1.14e-124 - - - L - - - Integrase
EKFEBFEA_01977 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
EKFEBFEA_01978 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EKFEBFEA_01979 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01980 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EKFEBFEA_01981 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EKFEBFEA_01982 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EKFEBFEA_01983 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_01984 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKFEBFEA_01985 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFEBFEA_01986 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EKFEBFEA_01987 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_01988 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
EKFEBFEA_01989 1.34e-185 yoxB - - - - - - -
EKFEBFEA_01990 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EKFEBFEA_01991 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
EKFEBFEA_01992 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EKFEBFEA_01993 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFEBFEA_01994 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFEBFEA_01995 2.08e-44 yoaF - - - - - - -
EKFEBFEA_01997 1.25e-20 - - - - - - - -
EKFEBFEA_01998 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
EKFEBFEA_01999 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
EKFEBFEA_02000 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EKFEBFEA_02001 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
EKFEBFEA_02002 1.79e-145 yoaK - - S - - - Membrane
EKFEBFEA_02003 1.5e-254 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
EKFEBFEA_02004 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EKFEBFEA_02006 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EKFEBFEA_02008 4.7e-188 yoaP - - K - - - YoaP-like
EKFEBFEA_02009 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EKFEBFEA_02010 2.36e-116 - - - - - - - -
EKFEBFEA_02011 3.63e-218 yoaR - - V - - - vancomycin resistance protein
EKFEBFEA_02012 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
EKFEBFEA_02013 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_02014 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
EKFEBFEA_02015 6.67e-203 yoaU - - K - - - LysR substrate binding domain
EKFEBFEA_02016 1.11e-202 yoaV - - EG - - - EamA-like transporter family
EKFEBFEA_02017 6.84e-103 yoaW - - - - - - -
EKFEBFEA_02018 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
EKFEBFEA_02019 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EKFEBFEA_02023 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EKFEBFEA_02024 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EKFEBFEA_02025 6.27e-51 - - - S - - - TM2 domain
EKFEBFEA_02026 3.92e-76 - - - K - - - Helix-turn-helix
EKFEBFEA_02028 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EKFEBFEA_02029 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EKFEBFEA_02030 6.85e-229 - - - - - - - -
EKFEBFEA_02031 1.36e-08 - - - - - - - -
EKFEBFEA_02035 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EKFEBFEA_02037 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFEBFEA_02038 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFEBFEA_02039 2.05e-51 - - - S - - - YolD-like protein
EKFEBFEA_02040 2.08e-64 - - - - - - - -
EKFEBFEA_02041 0.0 - - - K - - - Psort location Cytoplasmic, score
EKFEBFEA_02042 3.58e-202 - - - - - - - -
EKFEBFEA_02043 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EKFEBFEA_02044 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EKFEBFEA_02045 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
EKFEBFEA_02046 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
EKFEBFEA_02047 0.0 yobO - - M - - - Pectate lyase superfamily protein
EKFEBFEA_02048 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EKFEBFEA_02049 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EKFEBFEA_02050 1.29e-183 - - - J - - - FR47-like protein
EKFEBFEA_02051 9.22e-129 yobS - - K - - - Transcriptional regulator
EKFEBFEA_02052 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EKFEBFEA_02053 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
EKFEBFEA_02054 2.05e-229 yobV - - K - - - WYL domain
EKFEBFEA_02055 7.69e-123 yobW - - - - - - -
EKFEBFEA_02056 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EKFEBFEA_02057 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKFEBFEA_02058 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
EKFEBFEA_02059 4.49e-186 - - - - - - - -
EKFEBFEA_02060 1.32e-122 yocC - - - - - - -
EKFEBFEA_02061 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EKFEBFEA_02062 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EKFEBFEA_02063 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_02064 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_02065 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
EKFEBFEA_02066 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EKFEBFEA_02067 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKFEBFEA_02068 1.42e-107 yocK - - T - - - general stress protein
EKFEBFEA_02069 3.02e-70 yocL - - - - - - -
EKFEBFEA_02070 7.29e-46 - - - - - - - -
EKFEBFEA_02071 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EKFEBFEA_02072 2.94e-55 yozN - - - - - - -
EKFEBFEA_02073 1.83e-49 yocN - - - - - - -
EKFEBFEA_02074 2.17e-74 yozO - - S - - - Bacterial PH domain
EKFEBFEA_02075 1.91e-42 yozC - - - - - - -
EKFEBFEA_02076 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EKFEBFEA_02077 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EKFEBFEA_02078 3.35e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EKFEBFEA_02079 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EKFEBFEA_02080 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
EKFEBFEA_02081 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EKFEBFEA_02082 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EKFEBFEA_02083 0.0 yojO - - P - - - Von Willebrand factor
EKFEBFEA_02084 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EKFEBFEA_02085 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EKFEBFEA_02086 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EKFEBFEA_02087 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EKFEBFEA_02088 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKFEBFEA_02090 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EKFEBFEA_02091 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFEBFEA_02092 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EKFEBFEA_02093 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EKFEBFEA_02094 1.85e-58 - - - - - - - -
EKFEBFEA_02095 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EKFEBFEA_02096 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EKFEBFEA_02097 1.95e-14 - - - - - - - -
EKFEBFEA_02098 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EKFEBFEA_02099 2.05e-86 iolK - - S - - - tautomerase
EKFEBFEA_02100 1.37e-76 yodB - - K - - - transcriptional
EKFEBFEA_02101 1.92e-140 yodC - - C - - - nitroreductase
EKFEBFEA_02102 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EKFEBFEA_02103 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EKFEBFEA_02104 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
EKFEBFEA_02105 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFEBFEA_02106 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EKFEBFEA_02107 6.38e-168 yodH - - Q - - - Methyltransferase
EKFEBFEA_02108 2.93e-42 yodI - - - - - - -
EKFEBFEA_02109 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EKFEBFEA_02110 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EKFEBFEA_02111 2.08e-12 - - - - - - - -
EKFEBFEA_02112 1.17e-71 yodL - - S - - - YodL-like
EKFEBFEA_02113 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EKFEBFEA_02114 5.18e-34 yozD - - S - - - YozD-like protein
EKFEBFEA_02116 3.84e-161 yodN - - - - - - -
EKFEBFEA_02117 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
EKFEBFEA_02118 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
EKFEBFEA_02119 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EKFEBFEA_02120 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EKFEBFEA_02121 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EKFEBFEA_02122 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKFEBFEA_02124 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKFEBFEA_02127 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EKFEBFEA_02128 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EKFEBFEA_02129 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
EKFEBFEA_02130 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
EKFEBFEA_02131 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EKFEBFEA_02132 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EKFEBFEA_02133 1.13e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EKFEBFEA_02135 1.31e-139 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKFEBFEA_02144 6.52e-216 - - - S - - - Calcineurin-like phosphoesterase
EKFEBFEA_02145 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EKFEBFEA_02150 2.85e-107 - - - L - - - Bacterial transcription activator, effector binding domain
EKFEBFEA_02151 3.02e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EKFEBFEA_02152 2.34e-51 - - - O - - - Glutaredoxin
EKFEBFEA_02153 1.12e-87 - - - S - - - Ribonucleotide reductase, small chain
EKFEBFEA_02154 3.73e-126 - - - L - - - HNH endonuclease
EKFEBFEA_02155 1.59e-139 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFEBFEA_02156 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFEBFEA_02157 1.71e-160 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKFEBFEA_02158 7.75e-87 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EKFEBFEA_02175 0.0 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
EKFEBFEA_02177 1.71e-126 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EKFEBFEA_02178 3.92e-115 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
EKFEBFEA_02183 9.54e-147 - - - S - - - protein conserved in bacteria
EKFEBFEA_02184 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EKFEBFEA_02185 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EKFEBFEA_02186 3.45e-288 - - - L - - - DNA primase activity
EKFEBFEA_02187 0.0 - - - J - - - DnaB-like helicase C terminal domain
EKFEBFEA_02188 1.1e-112 - - - - - - - -
EKFEBFEA_02189 6.35e-229 - - - L - - - AAA domain
EKFEBFEA_02190 2.37e-219 - - - - - - - -
EKFEBFEA_02195 0.0 - - - M - - - Parallel beta-helix repeats
EKFEBFEA_02196 1.83e-192 - - - S - - - Pfam:DUF867
EKFEBFEA_02199 2.62e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EKFEBFEA_02200 3.73e-199 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
EKFEBFEA_02201 6.17e-103 - - - - - - - -
EKFEBFEA_02208 3.88e-60 - - - - - - - -
EKFEBFEA_02210 9.17e-126 - - - S - - - Protein of unknown function (DUF1273)
EKFEBFEA_02212 1.16e-102 yoqH - - M - - - LysM domain
EKFEBFEA_02215 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
EKFEBFEA_02216 2.12e-175 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
EKFEBFEA_02222 0.000573 - - - S - - - YopX protein
EKFEBFEA_02227 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_02228 2.89e-226 - - - - - - - -
EKFEBFEA_02229 0.0 - - - S - - - DNA-sulfur modification-associated
EKFEBFEA_02230 2.04e-254 - - - L - - - Belongs to the 'phage' integrase family
EKFEBFEA_02235 7.95e-135 - - - - - - - -
EKFEBFEA_02237 8.39e-125 - - - - - - - -
EKFEBFEA_02238 2.68e-124 - - - S - - - Super-infection exclusion protein B
EKFEBFEA_02244 0.0 - - - - - - - -
EKFEBFEA_02245 7.56e-48 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EKFEBFEA_02246 0.0 - - - - - - - -
EKFEBFEA_02248 1.07e-305 - - - - - - - -
EKFEBFEA_02251 6.64e-73 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
EKFEBFEA_02254 0.0 - - - - - - - -
EKFEBFEA_02255 7.27e-56 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKFEBFEA_02257 2.29e-293 - - - - - - - -
EKFEBFEA_02260 4.45e-225 - - - - - - - -
EKFEBFEA_02261 0.0 - - - S - - - Terminase-like family
EKFEBFEA_02262 0.0 - - - - - - - -
EKFEBFEA_02263 0.0 - - - - - - - -
EKFEBFEA_02264 1.24e-122 - - - - - - - -
EKFEBFEA_02265 5.93e-237 - - - - - - - -
EKFEBFEA_02266 8.05e-106 - - - - - - - -
EKFEBFEA_02267 8.95e-91 - - - - - - - -
EKFEBFEA_02269 9.48e-157 - - - - - - - -
EKFEBFEA_02270 4.38e-118 - - - - - - - -
EKFEBFEA_02271 2.4e-169 - - - - - - - -
EKFEBFEA_02272 1.58e-145 - - - - - - - -
EKFEBFEA_02275 2.22e-76 - - - - - - - -
EKFEBFEA_02276 4.46e-229 - - - - - - - -
EKFEBFEA_02279 1.65e-112 - - - - - - - -
EKFEBFEA_02280 2e-94 - - - - - - - -
EKFEBFEA_02281 1.73e-247 - - - A - - - Belongs to the 'phage' integrase family
EKFEBFEA_02286 5.66e-159 - - - - - - - -
EKFEBFEA_02287 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EKFEBFEA_02288 1.7e-186 - - - S - - - Phage tail protein
EKFEBFEA_02289 0.0 - - - S - - - Pfam Transposase IS66
EKFEBFEA_02290 9.28e-166 - - - - - - - -
EKFEBFEA_02291 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
EKFEBFEA_02292 1.31e-210 - - - - - - - -
EKFEBFEA_02294 7.44e-257 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
EKFEBFEA_02295 1.42e-43 bhlA - - S - - - BhlA holin family
EKFEBFEA_02296 3.04e-53 - - - S - - - SPP1 phage holin
EKFEBFEA_02297 5.12e-96 - - - O ko:K03611 - ko00000,ko03110 protein disulfide oxidoreductase activity
EKFEBFEA_02298 6.04e-309 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_02299 3.44e-91 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
EKFEBFEA_02300 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 Peptidase C39 family
EKFEBFEA_02303 2.97e-306 - - - S - - - damaged DNA binding
EKFEBFEA_02304 7.69e-73 - - - S - - - YolD-like protein
EKFEBFEA_02305 1.42e-55 - - - - - - - -
EKFEBFEA_02309 5.26e-128 - - - J - - - Acetyltransferase (GNAT) domain
EKFEBFEA_02310 5.38e-142 yokK - - S - - - SMI1 / KNR4 family
EKFEBFEA_02311 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
EKFEBFEA_02312 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
EKFEBFEA_02313 2.64e-119 yokH - - G - - - SMI1 / KNR4 family
EKFEBFEA_02314 5.27e-261 - - - - - - - -
EKFEBFEA_02315 2.55e-178 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EKFEBFEA_02316 6.83e-109 - - - S - - - Bacterial PH domain
EKFEBFEA_02317 8.79e-199 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
EKFEBFEA_02320 5.1e-123 - - - - - - - -
EKFEBFEA_02321 4.93e-153 - - - - - - - -
EKFEBFEA_02322 0.0 yokA - - L - - - Recombinase
EKFEBFEA_02323 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EKFEBFEA_02324 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EKFEBFEA_02325 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKFEBFEA_02326 4.14e-94 ypoP - - K - - - transcriptional
EKFEBFEA_02327 3.49e-290 mepA - - V - - - MATE efflux family protein
EKFEBFEA_02328 2.13e-40 ypmT - - S - - - Uncharacterized ympT
EKFEBFEA_02329 6.8e-129 ypmS - - S - - - protein conserved in bacteria
EKFEBFEA_02330 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EKFEBFEA_02331 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EKFEBFEA_02332 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EKFEBFEA_02333 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EKFEBFEA_02334 1.4e-236 yplP - - K - - - Transcriptional regulator
EKFEBFEA_02335 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EKFEBFEA_02336 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EKFEBFEA_02337 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKFEBFEA_02338 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKFEBFEA_02339 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EKFEBFEA_02340 3.47e-148 ypjP - - S - - - YpjP-like protein
EKFEBFEA_02341 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EKFEBFEA_02342 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
EKFEBFEA_02343 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EKFEBFEA_02344 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EKFEBFEA_02345 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EKFEBFEA_02346 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EKFEBFEA_02347 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EKFEBFEA_02348 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EKFEBFEA_02349 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EKFEBFEA_02350 1.17e-22 degR - - - - - - -
EKFEBFEA_02351 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
EKFEBFEA_02352 1.54e-37 ypeQ - - S - - - Zinc-finger
EKFEBFEA_02353 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EKFEBFEA_02354 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EKFEBFEA_02355 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EKFEBFEA_02356 5.23e-05 - - - - ko:K06429 - ko00000 -
EKFEBFEA_02357 2.26e-213 ypcP - - L - - - 5'3' exonuclease
EKFEBFEA_02358 1.08e-11 - - - - - - - -
EKFEBFEA_02359 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
EKFEBFEA_02360 0.0 ypbR - - S - - - Dynamin family
EKFEBFEA_02361 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EKFEBFEA_02362 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EKFEBFEA_02363 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EKFEBFEA_02364 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EKFEBFEA_02365 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EKFEBFEA_02366 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EKFEBFEA_02367 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EKFEBFEA_02368 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EKFEBFEA_02369 1.92e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
EKFEBFEA_02370 1.25e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EKFEBFEA_02371 2.05e-179 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_02372 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EKFEBFEA_02374 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EKFEBFEA_02375 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EKFEBFEA_02376 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
EKFEBFEA_02377 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EKFEBFEA_02378 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EKFEBFEA_02379 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EKFEBFEA_02380 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EKFEBFEA_02381 8.72e-68 yppG - - S - - - YppG-like protein
EKFEBFEA_02382 9.21e-11 - - - S - - - YppF-like protein
EKFEBFEA_02383 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
EKFEBFEA_02386 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
EKFEBFEA_02387 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKFEBFEA_02388 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EKFEBFEA_02389 1.43e-121 ypoC - - - - - - -
EKFEBFEA_02390 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKFEBFEA_02391 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EKFEBFEA_02392 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EKFEBFEA_02393 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EKFEBFEA_02394 2.27e-103 ypmB - - S - - - protein conserved in bacteria
EKFEBFEA_02395 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EKFEBFEA_02396 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EKFEBFEA_02397 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EKFEBFEA_02398 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EKFEBFEA_02399 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EKFEBFEA_02400 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EKFEBFEA_02401 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EKFEBFEA_02402 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EKFEBFEA_02403 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EKFEBFEA_02404 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EKFEBFEA_02405 8.38e-190 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EKFEBFEA_02406 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EKFEBFEA_02407 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EKFEBFEA_02408 6.84e-183 ypjB - - S - - - sporulation protein
EKFEBFEA_02409 1.63e-125 ypjA - - S - - - membrane
EKFEBFEA_02410 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EKFEBFEA_02411 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EKFEBFEA_02412 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EKFEBFEA_02413 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
EKFEBFEA_02414 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
EKFEBFEA_02415 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
EKFEBFEA_02416 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EKFEBFEA_02417 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EKFEBFEA_02418 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKFEBFEA_02419 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EKFEBFEA_02420 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EKFEBFEA_02421 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EKFEBFEA_02422 3.84e-143 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EKFEBFEA_02423 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EKFEBFEA_02424 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EKFEBFEA_02425 3.42e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EKFEBFEA_02426 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EKFEBFEA_02427 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKFEBFEA_02428 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EKFEBFEA_02429 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EKFEBFEA_02430 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EKFEBFEA_02431 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EKFEBFEA_02432 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EKFEBFEA_02433 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EKFEBFEA_02434 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EKFEBFEA_02435 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKFEBFEA_02436 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EKFEBFEA_02437 9.07e-178 yphF - - - - - - -
EKFEBFEA_02438 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
EKFEBFEA_02439 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EKFEBFEA_02440 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EKFEBFEA_02441 8.69e-40 ypzH - - - - - - -
EKFEBFEA_02442 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
EKFEBFEA_02443 2.73e-134 yphA - - - - - - -
EKFEBFEA_02444 1.13e-11 - - - S - - - YpzI-like protein
EKFEBFEA_02445 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EKFEBFEA_02446 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EKFEBFEA_02447 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EKFEBFEA_02448 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
EKFEBFEA_02449 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
EKFEBFEA_02450 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EKFEBFEA_02451 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EKFEBFEA_02452 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EKFEBFEA_02453 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EKFEBFEA_02454 3.96e-312 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EKFEBFEA_02455 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EKFEBFEA_02456 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EKFEBFEA_02457 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
EKFEBFEA_02458 5.04e-148 ypbE - - M - - - Lysin motif
EKFEBFEA_02459 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EKFEBFEA_02460 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EKFEBFEA_02461 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EKFEBFEA_02462 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EKFEBFEA_02463 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EKFEBFEA_02464 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFEBFEA_02465 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EKFEBFEA_02466 2.7e-257 rsiX - - - - - - -
EKFEBFEA_02467 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_02468 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_02469 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_02470 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EKFEBFEA_02471 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EKFEBFEA_02472 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EKFEBFEA_02473 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EKFEBFEA_02474 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EKFEBFEA_02475 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EKFEBFEA_02476 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EKFEBFEA_02477 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
EKFEBFEA_02478 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKFEBFEA_02479 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKFEBFEA_02480 3.18e-123 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EKFEBFEA_02481 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_02482 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EKFEBFEA_02483 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKFEBFEA_02484 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EKFEBFEA_02485 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKFEBFEA_02486 2.96e-72 ypuD - - - - - - -
EKFEBFEA_02487 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EKFEBFEA_02488 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
EKFEBFEA_02490 3.82e-09 - - - S - - - SNARE associated Golgi protein
EKFEBFEA_02492 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKFEBFEA_02493 2.67e-193 ypuA - - S - - - Secreted protein
EKFEBFEA_02494 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EKFEBFEA_02495 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EKFEBFEA_02496 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
EKFEBFEA_02497 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EKFEBFEA_02498 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EKFEBFEA_02499 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EKFEBFEA_02500 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
EKFEBFEA_02501 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EKFEBFEA_02502 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_02503 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EKFEBFEA_02504 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EKFEBFEA_02505 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EKFEBFEA_02506 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EKFEBFEA_02507 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EKFEBFEA_02508 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EKFEBFEA_02509 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
EKFEBFEA_02510 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EKFEBFEA_02511 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EKFEBFEA_02512 3.73e-44 yqkK - - - - - - -
EKFEBFEA_02513 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EKFEBFEA_02514 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EKFEBFEA_02515 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EKFEBFEA_02516 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EKFEBFEA_02517 3.18e-77 ansR - - K - - - Transcriptional regulator
EKFEBFEA_02518 2.62e-283 yqxK - - L - - - DNA helicase
EKFEBFEA_02519 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EKFEBFEA_02520 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
EKFEBFEA_02521 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EKFEBFEA_02522 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
EKFEBFEA_02523 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EKFEBFEA_02524 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
EKFEBFEA_02525 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
EKFEBFEA_02526 2.89e-251 yqkA - - K - - - GrpB protein
EKFEBFEA_02527 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EKFEBFEA_02528 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EKFEBFEA_02529 1.87e-65 yqiX - - S - - - YolD-like protein
EKFEBFEA_02530 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFEBFEA_02532 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
EKFEBFEA_02534 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_02535 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EKFEBFEA_02536 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EKFEBFEA_02537 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_02538 3.98e-230 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EKFEBFEA_02539 6.84e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFEBFEA_02540 0.0 rocB - - E - - - arginine degradation protein
EKFEBFEA_02541 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EKFEBFEA_02542 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EKFEBFEA_02543 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EKFEBFEA_02544 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKFEBFEA_02545 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKFEBFEA_02546 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKFEBFEA_02547 1.77e-32 yqzJ - - - - - - -
EKFEBFEA_02548 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKFEBFEA_02549 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
EKFEBFEA_02550 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EKFEBFEA_02551 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EKFEBFEA_02552 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EKFEBFEA_02554 2.41e-128 yqjB - - S - - - protein conserved in bacteria
EKFEBFEA_02555 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EKFEBFEA_02556 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EKFEBFEA_02557 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EKFEBFEA_02558 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EKFEBFEA_02559 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
EKFEBFEA_02560 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EKFEBFEA_02561 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_02562 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
EKFEBFEA_02563 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKFEBFEA_02564 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EKFEBFEA_02565 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EKFEBFEA_02566 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EKFEBFEA_02567 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EKFEBFEA_02568 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EKFEBFEA_02569 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EKFEBFEA_02570 0.0 bkdR - - KT - - - Transcriptional regulator
EKFEBFEA_02571 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EKFEBFEA_02572 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EKFEBFEA_02573 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EKFEBFEA_02574 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EKFEBFEA_02575 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EKFEBFEA_02576 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EKFEBFEA_02577 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EKFEBFEA_02578 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EKFEBFEA_02579 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EKFEBFEA_02580 2.26e-37 - - - - - - - -
EKFEBFEA_02581 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EKFEBFEA_02583 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EKFEBFEA_02584 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EKFEBFEA_02585 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EKFEBFEA_02586 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EKFEBFEA_02587 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EKFEBFEA_02588 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKFEBFEA_02589 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EKFEBFEA_02590 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKFEBFEA_02591 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKFEBFEA_02592 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKFEBFEA_02593 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKFEBFEA_02594 1.65e-88 yqhY - - S - - - protein conserved in bacteria
EKFEBFEA_02595 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EKFEBFEA_02596 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKFEBFEA_02597 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EKFEBFEA_02598 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EKFEBFEA_02599 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EKFEBFEA_02600 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EKFEBFEA_02601 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EKFEBFEA_02602 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EKFEBFEA_02603 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EKFEBFEA_02604 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EKFEBFEA_02605 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EKFEBFEA_02606 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKFEBFEA_02607 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EKFEBFEA_02608 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
EKFEBFEA_02609 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
EKFEBFEA_02610 3.79e-223 yqhQ - - S - - - Protein of unknown function (DUF1385)
EKFEBFEA_02611 5.18e-81 yqhP - - - - - - -
EKFEBFEA_02612 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EKFEBFEA_02613 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EKFEBFEA_02614 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EKFEBFEA_02615 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EKFEBFEA_02616 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKFEBFEA_02617 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EKFEBFEA_02618 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EKFEBFEA_02619 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKFEBFEA_02620 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
EKFEBFEA_02621 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EKFEBFEA_02622 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EKFEBFEA_02623 1.56e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EKFEBFEA_02624 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EKFEBFEA_02625 8.73e-160 yqxM - - - ko:K19433 - ko00000 -
EKFEBFEA_02626 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
EKFEBFEA_02627 4.9e-37 yqzE - - S - - - YqzE-like protein
EKFEBFEA_02628 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EKFEBFEA_02629 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EKFEBFEA_02630 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EKFEBFEA_02631 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
EKFEBFEA_02632 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EKFEBFEA_02633 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EKFEBFEA_02634 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EKFEBFEA_02636 1.51e-233 yqxL - - P - - - Mg2 transporter protein
EKFEBFEA_02637 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EKFEBFEA_02638 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EKFEBFEA_02640 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EKFEBFEA_02641 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EKFEBFEA_02642 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EKFEBFEA_02643 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
EKFEBFEA_02644 7.34e-66 yqgV - - S - - - Thiamine-binding protein
EKFEBFEA_02645 5.65e-258 yqgU - - - - - - -
EKFEBFEA_02646 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EKFEBFEA_02647 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EKFEBFEA_02648 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EKFEBFEA_02649 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
EKFEBFEA_02650 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
EKFEBFEA_02651 3.38e-14 yqgO - - - - - - -
EKFEBFEA_02652 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKFEBFEA_02653 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EKFEBFEA_02654 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
EKFEBFEA_02656 3.42e-68 yqzD - - - - - - -
EKFEBFEA_02657 2.92e-98 yqzC - - S - - - YceG-like family
EKFEBFEA_02658 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKFEBFEA_02659 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKFEBFEA_02660 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EKFEBFEA_02661 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EKFEBFEA_02662 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EKFEBFEA_02663 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EKFEBFEA_02664 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EKFEBFEA_02665 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EKFEBFEA_02666 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EKFEBFEA_02667 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
EKFEBFEA_02668 2.05e-99 yqgA - - - - - - -
EKFEBFEA_02669 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
EKFEBFEA_02670 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EKFEBFEA_02671 2.04e-81 yqfX - - S - - - membrane
EKFEBFEA_02672 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EKFEBFEA_02673 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EKFEBFEA_02674 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EKFEBFEA_02675 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EKFEBFEA_02676 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EKFEBFEA_02677 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKFEBFEA_02678 4.89e-58 yqfQ - - S - - - YqfQ-like protein
EKFEBFEA_02679 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EKFEBFEA_02680 2.27e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKFEBFEA_02681 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EKFEBFEA_02682 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EKFEBFEA_02683 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EKFEBFEA_02684 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKFEBFEA_02685 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EKFEBFEA_02686 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EKFEBFEA_02687 3.29e-144 ccpN - - K - - - CBS domain
EKFEBFEA_02688 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EKFEBFEA_02689 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EKFEBFEA_02690 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EKFEBFEA_02691 5.29e-27 - - - S - - - YqzL-like protein
EKFEBFEA_02692 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKFEBFEA_02693 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EKFEBFEA_02694 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EKFEBFEA_02695 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKFEBFEA_02696 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EKFEBFEA_02698 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EKFEBFEA_02699 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EKFEBFEA_02700 2.07e-60 yqfC - - S - - - sporulation protein YqfC
EKFEBFEA_02701 3.13e-79 yqfB - - - - - - -
EKFEBFEA_02702 4.35e-192 yqfA - - S - - - UPF0365 protein
EKFEBFEA_02703 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EKFEBFEA_02704 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EKFEBFEA_02705 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EKFEBFEA_02706 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EKFEBFEA_02707 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EKFEBFEA_02708 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EKFEBFEA_02709 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EKFEBFEA_02710 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKFEBFEA_02711 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EKFEBFEA_02712 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKFEBFEA_02713 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EKFEBFEA_02714 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EKFEBFEA_02715 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EKFEBFEA_02716 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
EKFEBFEA_02717 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EKFEBFEA_02718 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EKFEBFEA_02719 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EKFEBFEA_02720 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EKFEBFEA_02721 2.36e-22 - - - S - - - YqzM-like protein
EKFEBFEA_02722 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EKFEBFEA_02723 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EKFEBFEA_02724 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EKFEBFEA_02725 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKFEBFEA_02726 9.8e-179 yqeM - - Q - - - Methyltransferase
EKFEBFEA_02727 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EKFEBFEA_02728 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EKFEBFEA_02729 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKFEBFEA_02730 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EKFEBFEA_02731 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKFEBFEA_02732 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EKFEBFEA_02733 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EKFEBFEA_02735 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EKFEBFEA_02736 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EKFEBFEA_02737 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
EKFEBFEA_02738 7.95e-219 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
EKFEBFEA_02739 9.38e-171 - - - - - - - -
EKFEBFEA_02740 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
EKFEBFEA_02741 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_02742 0.0 - - - L ko:K06400 - ko00000 Recombinase
EKFEBFEA_02743 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EKFEBFEA_02744 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
EKFEBFEA_02745 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_02746 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
EKFEBFEA_02747 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EKFEBFEA_02748 8.68e-120 - - - S - - - Tetratricopeptide repeat
EKFEBFEA_02751 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EKFEBFEA_02752 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
EKFEBFEA_02754 5.4e-80 - - - - - - - -
EKFEBFEA_02756 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EKFEBFEA_02757 8.36e-89 - - - S - - - Bacteriophage holin family
EKFEBFEA_02758 2.45e-213 xepA - - - - - - -
EKFEBFEA_02759 9.34e-33 - - - - - - - -
EKFEBFEA_02760 1.01e-73 xkdW - - S - - - XkdW protein
EKFEBFEA_02761 2.91e-283 - - - - - - - -
EKFEBFEA_02762 3e-54 - - - - - - - -
EKFEBFEA_02763 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EKFEBFEA_02764 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EKFEBFEA_02765 6.6e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
EKFEBFEA_02766 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
EKFEBFEA_02767 1.02e-231 xkdQ - - G - - - NLP P60 protein
EKFEBFEA_02768 6.56e-156 xkdP - - S - - - Lysin motif
EKFEBFEA_02769 0.0 xkdO - - L - - - Transglycosylase SLT domain
EKFEBFEA_02770 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EKFEBFEA_02772 4.23e-99 xkdM - - S - - - Phage tail tube protein
EKFEBFEA_02773 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EKFEBFEA_02774 2.52e-36 - - - - - - - -
EKFEBFEA_02775 3.24e-102 yqbJ - - - - - - -
EKFEBFEA_02776 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EKFEBFEA_02777 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
EKFEBFEA_02778 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
EKFEBFEA_02779 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
EKFEBFEA_02780 9.21e-216 xkdG - - S - - - Phage capsid family
EKFEBFEA_02781 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
EKFEBFEA_02782 2.13e-149 - - - - - - - -
EKFEBFEA_02783 1.73e-217 - - - S - - - Phage Mu protein F like protein
EKFEBFEA_02784 0.0 yqbA - - S - - - portal protein
EKFEBFEA_02785 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
EKFEBFEA_02786 2.02e-158 yqaS - - L - - - DNA packaging
EKFEBFEA_02788 1.58e-105 yqaQ - - L - - - Transposase
EKFEBFEA_02789 7.56e-214 - - - - - - - -
EKFEBFEA_02790 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
EKFEBFEA_02791 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
EKFEBFEA_02793 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
EKFEBFEA_02794 3.33e-159 yqaL - - L - - - DnaD domain protein
EKFEBFEA_02795 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
EKFEBFEA_02796 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
EKFEBFEA_02800 1.27e-134 - - - - - - - -
EKFEBFEA_02802 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
EKFEBFEA_02803 1.25e-74 - - - K - - - sequence-specific DNA binding
EKFEBFEA_02805 8.73e-132 yqaC - - F - - - adenylate kinase activity
EKFEBFEA_02806 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
EKFEBFEA_02807 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EKFEBFEA_02808 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
EKFEBFEA_02809 7.32e-306 yrkQ - - T - - - Histidine kinase
EKFEBFEA_02810 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EKFEBFEA_02811 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EKFEBFEA_02812 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
EKFEBFEA_02813 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EKFEBFEA_02814 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
EKFEBFEA_02815 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
EKFEBFEA_02816 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
EKFEBFEA_02817 8.07e-282 yrkH - - P - - - Rhodanese Homology Domain
EKFEBFEA_02818 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
EKFEBFEA_02819 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
EKFEBFEA_02820 4.38e-52 yrkD - - S - - - protein conserved in bacteria
EKFEBFEA_02821 3.81e-139 yrkC - - G - - - Cupin domain
EKFEBFEA_02822 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
EKFEBFEA_02823 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_02824 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EKFEBFEA_02825 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EKFEBFEA_02826 7.28e-25 - - - S - - - YrzO-like protein
EKFEBFEA_02827 1.53e-219 yrdR - - EG - - - EamA-like transporter family
EKFEBFEA_02828 1.2e-204 - - - K - - - Transcriptional regulator
EKFEBFEA_02829 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EKFEBFEA_02830 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EKFEBFEA_02831 1.75e-87 yodA - - S - - - tautomerase
EKFEBFEA_02832 2.08e-209 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EKFEBFEA_02834 2.22e-295 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EKFEBFEA_02835 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
EKFEBFEA_02836 2.29e-176 azlC - - E - - - AzlC protein
EKFEBFEA_02837 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
EKFEBFEA_02838 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EKFEBFEA_02839 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EKFEBFEA_02840 7.37e-133 yrdC - - Q - - - Isochorismatase family
EKFEBFEA_02841 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
EKFEBFEA_02842 1.47e-120 yrdA - - S - - - DinB family
EKFEBFEA_02843 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EKFEBFEA_02844 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EKFEBFEA_02845 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EKFEBFEA_02846 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
EKFEBFEA_02848 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EKFEBFEA_02849 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_02850 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
EKFEBFEA_02851 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EKFEBFEA_02852 5.13e-211 yraN - - K - - - Transcriptional regulator
EKFEBFEA_02853 7.25e-264 yraM - - S - - - PrpF protein
EKFEBFEA_02855 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EKFEBFEA_02856 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_02857 4.9e-200 - - - S - - - Alpha beta hydrolase
EKFEBFEA_02858 6.61e-80 - - - T - - - sh3 domain protein
EKFEBFEA_02859 2.92e-81 - - - T - - - sh3 domain protein
EKFEBFEA_02860 6.62e-87 - - - E - - - Glyoxalase-like domain
EKFEBFEA_02861 4.19e-50 yraG - - - ko:K06440 - ko00000 -
EKFEBFEA_02862 9.61e-84 yraF - - M - - - Spore coat protein
EKFEBFEA_02863 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKFEBFEA_02864 1.05e-36 yraE - - - ko:K06440 - ko00000 -
EKFEBFEA_02865 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
EKFEBFEA_02866 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EKFEBFEA_02867 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
EKFEBFEA_02868 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EKFEBFEA_02869 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EKFEBFEA_02870 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EKFEBFEA_02871 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EKFEBFEA_02872 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EKFEBFEA_02873 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
EKFEBFEA_02874 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
EKFEBFEA_02875 0.0 levR - - K - - - PTS system fructose IIA component
EKFEBFEA_02876 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_02877 5.63e-137 yrhP - - E - - - LysE type translocator
EKFEBFEA_02878 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
EKFEBFEA_02879 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_02880 3.67e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
EKFEBFEA_02881 0.0 oatA - - I - - - Acyltransferase family
EKFEBFEA_02882 2.67e-62 yrhK - - S - - - YrhK-like protein
EKFEBFEA_02883 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EKFEBFEA_02884 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EKFEBFEA_02885 1.1e-126 yrhH - - Q - - - methyltransferase
EKFEBFEA_02886 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EKFEBFEA_02888 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EKFEBFEA_02889 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EKFEBFEA_02890 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EKFEBFEA_02891 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
EKFEBFEA_02892 6.93e-49 yrhC - - S - - - YrhC-like protein
EKFEBFEA_02893 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EKFEBFEA_02894 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EKFEBFEA_02895 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKFEBFEA_02896 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EKFEBFEA_02897 7.27e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
EKFEBFEA_02898 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
EKFEBFEA_02899 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EKFEBFEA_02900 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKFEBFEA_02901 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EKFEBFEA_02902 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EKFEBFEA_02903 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EKFEBFEA_02904 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EKFEBFEA_02905 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKFEBFEA_02906 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
EKFEBFEA_02907 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKFEBFEA_02908 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
EKFEBFEA_02909 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKFEBFEA_02910 3.07e-242 yrrI - - S - - - AI-2E family transporter
EKFEBFEA_02911 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EKFEBFEA_02912 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EKFEBFEA_02913 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_02914 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_02915 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
EKFEBFEA_02916 8.4e-42 yrzR - - - - - - -
EKFEBFEA_02917 1.23e-108 yrrD - - S - - - protein conserved in bacteria
EKFEBFEA_02918 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EKFEBFEA_02919 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
EKFEBFEA_02920 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EKFEBFEA_02921 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EKFEBFEA_02922 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_02923 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EKFEBFEA_02924 3.4e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EKFEBFEA_02925 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EKFEBFEA_02926 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EKFEBFEA_02928 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EKFEBFEA_02929 1.6e-89 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EKFEBFEA_02930 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKFEBFEA_02931 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKFEBFEA_02932 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EKFEBFEA_02933 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EKFEBFEA_02934 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EKFEBFEA_02935 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EKFEBFEA_02936 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
EKFEBFEA_02937 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_02938 6.34e-147 yrbG - - S - - - membrane
EKFEBFEA_02939 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
EKFEBFEA_02940 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EKFEBFEA_02941 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EKFEBFEA_02942 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKFEBFEA_02943 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
EKFEBFEA_02944 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EKFEBFEA_02945 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EKFEBFEA_02946 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EKFEBFEA_02947 0.0 csbX - - EGP - - - the major facilitator superfamily
EKFEBFEA_02948 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EKFEBFEA_02949 2.32e-152 yrzF - - T - - - serine threonine protein kinase
EKFEBFEA_02951 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
EKFEBFEA_02952 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
EKFEBFEA_02953 8.63e-165 yebC - - K - - - transcriptional regulatory protein
EKFEBFEA_02954 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFEBFEA_02955 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EKFEBFEA_02956 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EKFEBFEA_02957 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EKFEBFEA_02958 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EKFEBFEA_02959 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EKFEBFEA_02960 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EKFEBFEA_02961 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EKFEBFEA_02962 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EKFEBFEA_02963 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKFEBFEA_02964 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EKFEBFEA_02965 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EKFEBFEA_02966 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EKFEBFEA_02967 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EKFEBFEA_02968 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EKFEBFEA_02969 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EKFEBFEA_02970 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EKFEBFEA_02971 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EKFEBFEA_02972 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EKFEBFEA_02973 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EKFEBFEA_02974 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EKFEBFEA_02975 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EKFEBFEA_02976 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EKFEBFEA_02977 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EKFEBFEA_02978 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EKFEBFEA_02979 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EKFEBFEA_02980 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EKFEBFEA_02981 1.53e-35 - - - - - - - -
EKFEBFEA_02982 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EKFEBFEA_02983 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EKFEBFEA_02984 8.99e-315 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EKFEBFEA_02985 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EKFEBFEA_02986 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EKFEBFEA_02987 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EKFEBFEA_02988 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EKFEBFEA_02989 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EKFEBFEA_02990 8.23e-117 ysxD - - - - - - -
EKFEBFEA_02991 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EKFEBFEA_02992 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EKFEBFEA_02993 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EKFEBFEA_02994 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKFEBFEA_02995 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EKFEBFEA_02996 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
EKFEBFEA_02997 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKFEBFEA_02998 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EKFEBFEA_02999 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EKFEBFEA_03000 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EKFEBFEA_03001 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EKFEBFEA_03002 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EKFEBFEA_03003 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EKFEBFEA_03005 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EKFEBFEA_03006 1.01e-184 ysnF - - S - - - protein conserved in bacteria
EKFEBFEA_03008 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EKFEBFEA_03009 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKFEBFEA_03010 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EKFEBFEA_03011 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EKFEBFEA_03012 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EKFEBFEA_03013 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_03014 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_03015 1.6e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EKFEBFEA_03016 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EKFEBFEA_03017 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EKFEBFEA_03018 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EKFEBFEA_03019 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
EKFEBFEA_03020 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EKFEBFEA_03021 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EKFEBFEA_03022 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EKFEBFEA_03023 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EKFEBFEA_03025 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EKFEBFEA_03026 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EKFEBFEA_03027 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EKFEBFEA_03028 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_03029 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EKFEBFEA_03030 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
EKFEBFEA_03031 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKFEBFEA_03032 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EKFEBFEA_03033 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
EKFEBFEA_03034 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EKFEBFEA_03035 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKFEBFEA_03036 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKFEBFEA_03037 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKFEBFEA_03038 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKFEBFEA_03039 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EKFEBFEA_03040 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EKFEBFEA_03041 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
EKFEBFEA_03042 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EKFEBFEA_03043 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
EKFEBFEA_03045 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EKFEBFEA_03046 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EKFEBFEA_03047 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EKFEBFEA_03048 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EKFEBFEA_03049 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EKFEBFEA_03050 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EKFEBFEA_03051 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EKFEBFEA_03052 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EKFEBFEA_03053 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EKFEBFEA_03054 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EKFEBFEA_03055 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EKFEBFEA_03056 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
EKFEBFEA_03057 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
EKFEBFEA_03058 1.27e-59 ysdA - - S - - - Membrane
EKFEBFEA_03059 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKFEBFEA_03060 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EKFEBFEA_03061 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKFEBFEA_03063 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EKFEBFEA_03064 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EKFEBFEA_03065 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EKFEBFEA_03066 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03067 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EKFEBFEA_03068 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKFEBFEA_03069 5.98e-206 ytxC - - S - - - YtxC-like family
EKFEBFEA_03070 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
EKFEBFEA_03071 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EKFEBFEA_03072 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EKFEBFEA_03073 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKFEBFEA_03074 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EKFEBFEA_03075 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKFEBFEA_03076 9.85e-88 ytcD - - K - - - Transcriptional regulator
EKFEBFEA_03077 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EKFEBFEA_03078 4.54e-205 ytbE - - S - - - reductase
EKFEBFEA_03079 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKFEBFEA_03080 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EKFEBFEA_03081 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKFEBFEA_03082 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKFEBFEA_03083 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EKFEBFEA_03084 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_03085 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EKFEBFEA_03086 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EKFEBFEA_03087 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EKFEBFEA_03088 9.38e-95 ytwI - - S - - - membrane
EKFEBFEA_03089 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
EKFEBFEA_03090 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EKFEBFEA_03091 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EKFEBFEA_03092 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EKFEBFEA_03093 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EKFEBFEA_03094 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKFEBFEA_03095 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EKFEBFEA_03096 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EKFEBFEA_03097 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
EKFEBFEA_03098 5.12e-112 ytrI - - - - - - -
EKFEBFEA_03099 1.15e-39 - - - - - - - -
EKFEBFEA_03100 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EKFEBFEA_03101 2.15e-63 ytpI - - S - - - YtpI-like protein
EKFEBFEA_03102 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
EKFEBFEA_03103 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
EKFEBFEA_03104 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EKFEBFEA_03105 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
EKFEBFEA_03106 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_03107 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EKFEBFEA_03108 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_03109 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EKFEBFEA_03110 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_03111 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_03112 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EKFEBFEA_03113 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EKFEBFEA_03114 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EKFEBFEA_03115 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EKFEBFEA_03116 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
EKFEBFEA_03117 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_03119 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EKFEBFEA_03120 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EKFEBFEA_03121 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EKFEBFEA_03122 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKFEBFEA_03123 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EKFEBFEA_03124 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKFEBFEA_03125 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
EKFEBFEA_03126 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
EKFEBFEA_03127 7.05e-113 yteJ - - S - - - RDD family
EKFEBFEA_03128 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EKFEBFEA_03129 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKFEBFEA_03130 0.0 ytcJ - - S - - - amidohydrolase
EKFEBFEA_03131 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKFEBFEA_03132 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EKFEBFEA_03133 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKFEBFEA_03134 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EKFEBFEA_03135 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EKFEBFEA_03136 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EKFEBFEA_03137 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EKFEBFEA_03138 2.94e-142 yttP - - K - - - Transcriptional regulator
EKFEBFEA_03139 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EKFEBFEA_03140 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EKFEBFEA_03141 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKFEBFEA_03143 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKFEBFEA_03144 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EKFEBFEA_03145 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EKFEBFEA_03146 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EKFEBFEA_03147 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EKFEBFEA_03148 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EKFEBFEA_03149 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EKFEBFEA_03150 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EKFEBFEA_03151 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EKFEBFEA_03152 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
EKFEBFEA_03153 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EKFEBFEA_03154 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKFEBFEA_03155 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EKFEBFEA_03156 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EKFEBFEA_03157 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKFEBFEA_03158 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
EKFEBFEA_03159 3.17e-75 ytpP - - CO - - - Thioredoxin
EKFEBFEA_03160 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EKFEBFEA_03161 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EKFEBFEA_03162 4.06e-68 ytzB - - S - - - small secreted protein
EKFEBFEA_03163 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EKFEBFEA_03164 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EKFEBFEA_03165 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EKFEBFEA_03166 9.51e-61 ytzH - - S - - - YtzH-like protein
EKFEBFEA_03167 3.02e-192 ytmP - - M - - - Phosphotransferase
EKFEBFEA_03168 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EKFEBFEA_03169 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EKFEBFEA_03170 4.92e-212 ytlQ - - - - - - -
EKFEBFEA_03171 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EKFEBFEA_03172 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EKFEBFEA_03173 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EKFEBFEA_03174 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EKFEBFEA_03175 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EKFEBFEA_03176 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EKFEBFEA_03177 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EKFEBFEA_03178 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EKFEBFEA_03179 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_03180 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EKFEBFEA_03181 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EKFEBFEA_03182 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EKFEBFEA_03183 1.97e-152 yteU - - S - - - Integral membrane protein
EKFEBFEA_03184 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
EKFEBFEA_03185 5.81e-95 yteS - - G - - - transport
EKFEBFEA_03186 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EKFEBFEA_03187 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EKFEBFEA_03188 0.0 ytdP - - K - - - Transcriptional regulator
EKFEBFEA_03189 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EKFEBFEA_03190 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EKFEBFEA_03191 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
EKFEBFEA_03192 2.64e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EKFEBFEA_03193 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EKFEBFEA_03194 5.04e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EKFEBFEA_03195 3.73e-284 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EKFEBFEA_03196 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EKFEBFEA_03197 4.04e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EKFEBFEA_03198 1.43e-222 - - - S - - - Acetyl xylan esterase (AXE1)
EKFEBFEA_03199 1.12e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_03200 4.68e-315 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EKFEBFEA_03201 6.02e-217 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_03202 1.32e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EKFEBFEA_03203 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EKFEBFEA_03204 1.22e-68 ytwF - - P - - - Sulfurtransferase
EKFEBFEA_03205 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EKFEBFEA_03206 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
EKFEBFEA_03207 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EKFEBFEA_03208 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
EKFEBFEA_03209 2.02e-78 yttA - - S - - - Pfam Transposase IS66
EKFEBFEA_03210 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EKFEBFEA_03211 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03212 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EKFEBFEA_03213 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_03214 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EKFEBFEA_03215 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03216 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EKFEBFEA_03217 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EKFEBFEA_03218 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03219 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EKFEBFEA_03221 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
EKFEBFEA_03222 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EKFEBFEA_03223 6.76e-137 ytqB - - J - - - Putative rRNA methylase
EKFEBFEA_03224 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EKFEBFEA_03225 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EKFEBFEA_03226 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EKFEBFEA_03227 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_03228 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EKFEBFEA_03229 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKFEBFEA_03230 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EKFEBFEA_03231 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
EKFEBFEA_03232 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EKFEBFEA_03233 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EKFEBFEA_03234 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EKFEBFEA_03235 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EKFEBFEA_03236 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EKFEBFEA_03237 1.59e-81 ytkC - - S - - - Bacteriophage holin family
EKFEBFEA_03238 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EKFEBFEA_03240 8.26e-96 ytkA - - S - - - YtkA-like
EKFEBFEA_03241 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EKFEBFEA_03242 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EKFEBFEA_03243 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EKFEBFEA_03244 2.81e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EKFEBFEA_03245 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EKFEBFEA_03246 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EKFEBFEA_03247 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EKFEBFEA_03248 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EKFEBFEA_03249 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EKFEBFEA_03250 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EKFEBFEA_03251 1.22e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EKFEBFEA_03252 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EKFEBFEA_03253 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKFEBFEA_03254 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EKFEBFEA_03255 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EKFEBFEA_03256 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EKFEBFEA_03257 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
EKFEBFEA_03258 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
EKFEBFEA_03259 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFEBFEA_03260 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
EKFEBFEA_03261 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
EKFEBFEA_03263 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
EKFEBFEA_03264 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
EKFEBFEA_03265 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
EKFEBFEA_03266 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EKFEBFEA_03267 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EKFEBFEA_03268 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
EKFEBFEA_03269 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
EKFEBFEA_03270 2.96e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKFEBFEA_03271 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EKFEBFEA_03293 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EKFEBFEA_03294 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EKFEBFEA_03295 1.2e-122 - - - M - - - FR47-like protein
EKFEBFEA_03296 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EKFEBFEA_03297 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EKFEBFEA_03298 1.95e-109 yuaE - - S - - - DinB superfamily
EKFEBFEA_03299 8.58e-139 yuaD - - - - - - -
EKFEBFEA_03300 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EKFEBFEA_03301 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EKFEBFEA_03302 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EKFEBFEA_03303 5.83e-118 yuaB - - - - - - -
EKFEBFEA_03304 1.83e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EKFEBFEA_03305 1.85e-301 - - - P ko:K03498 - ko00000,ko02000 Potassium
EKFEBFEA_03306 3.31e-52 yubF - - S - - - yiaA/B two helix domain
EKFEBFEA_03307 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKFEBFEA_03308 0.0 yubD - - P - - - Major Facilitator Superfamily
EKFEBFEA_03309 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
EKFEBFEA_03311 6.02e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EKFEBFEA_03312 3.8e-256 yubA - - S - - - transporter activity
EKFEBFEA_03313 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EKFEBFEA_03314 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
EKFEBFEA_03315 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
EKFEBFEA_03316 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EKFEBFEA_03317 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EKFEBFEA_03318 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
EKFEBFEA_03319 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_03320 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_03321 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_03322 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_03323 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EKFEBFEA_03324 5e-48 - - - - - - - -
EKFEBFEA_03325 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
EKFEBFEA_03326 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EKFEBFEA_03327 1.07e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EKFEBFEA_03328 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EKFEBFEA_03329 1.35e-51 - - - - - - - -
EKFEBFEA_03330 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
EKFEBFEA_03331 1.76e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EKFEBFEA_03332 4.22e-95 yugN - - S - - - YugN-like family
EKFEBFEA_03334 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EKFEBFEA_03335 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EKFEBFEA_03336 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EKFEBFEA_03337 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EKFEBFEA_03338 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EKFEBFEA_03339 6.62e-256 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EKFEBFEA_03340 6.74e-112 alaR - - K - - - Transcriptional regulator
EKFEBFEA_03341 1.2e-201 yugF - - I - - - Hydrolase
EKFEBFEA_03342 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
EKFEBFEA_03343 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EKFEBFEA_03344 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03345 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EKFEBFEA_03346 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EKFEBFEA_03348 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
EKFEBFEA_03349 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EKFEBFEA_03350 3.31e-98 yuxK - - S - - - protein conserved in bacteria
EKFEBFEA_03351 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
EKFEBFEA_03352 1.68e-295 - - - L - - - DNA binding domain of tn916 integrase
EKFEBFEA_03353 3.87e-42 xis - - S - - - Excisionase from transposon Tn916
EKFEBFEA_03354 1.4e-48 - - - S - - - Helix-turn-helix domain
EKFEBFEA_03355 3.84e-94 - - - K - - - Sigma-70, region 4
EKFEBFEA_03356 8.07e-76 - - - K - - - Helix-turn-helix domain
EKFEBFEA_03357 0.0 - - - J - - - Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKFEBFEA_03358 7.95e-221 - - - S - - - Conjugative transposon protein TcpC
EKFEBFEA_03359 3.21e-243 - - - M - - - NlpC p60 family protein
EKFEBFEA_03360 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
EKFEBFEA_03361 0.0 - - - S - - - AAA-like domain
EKFEBFEA_03362 2.03e-88 - - - S - - - TcpE family
EKFEBFEA_03363 1.42e-117 - - - S - - - Antirestriction protein (ArdA)
EKFEBFEA_03364 3.41e-41 - - - S - - - Psort location CytoplasmicMembrane, score
EKFEBFEA_03365 1.82e-297 - - - K ko:K07467 - ko00000 Replication initiation factor
EKFEBFEA_03366 0.0 - - - D ko:K03466 - ko00000,ko03036 Domain of unknown function DUF87
EKFEBFEA_03367 1.39e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
EKFEBFEA_03368 1.6e-69 - - - S - - - Bacterial protein of unknown function (DUF961)
EKFEBFEA_03369 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EKFEBFEA_03370 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EKFEBFEA_03371 6.34e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EKFEBFEA_03372 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03373 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EKFEBFEA_03374 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EKFEBFEA_03375 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
EKFEBFEA_03376 7.06e-22 - - - - - - - -
EKFEBFEA_03377 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EKFEBFEA_03378 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFEBFEA_03379 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFEBFEA_03380 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFEBFEA_03381 7.39e-103 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFEBFEA_03382 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EKFEBFEA_03383 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EKFEBFEA_03384 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EKFEBFEA_03385 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_03386 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03388 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
EKFEBFEA_03389 6.29e-10 - - - S - - - DegQ (SacQ) family
EKFEBFEA_03390 9.63e-08 - - - - - - - -
EKFEBFEA_03391 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EKFEBFEA_03392 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKFEBFEA_03393 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EKFEBFEA_03394 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
EKFEBFEA_03395 1.63e-52 yueH - - S - - - YueH-like protein
EKFEBFEA_03396 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EKFEBFEA_03397 4.72e-245 yueF - - S - - - transporter activity
EKFEBFEA_03398 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
EKFEBFEA_03399 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
EKFEBFEA_03400 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EKFEBFEA_03401 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_03402 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
EKFEBFEA_03403 0.0 yueB - - S - - - type VII secretion protein EsaA
EKFEBFEA_03404 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EKFEBFEA_03405 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EKFEBFEA_03406 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EKFEBFEA_03407 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
EKFEBFEA_03408 1.03e-292 yukF - - QT - - - Transcriptional regulator
EKFEBFEA_03409 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EKFEBFEA_03410 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EKFEBFEA_03411 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EKFEBFEA_03412 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_03413 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EKFEBFEA_03414 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EKFEBFEA_03415 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EKFEBFEA_03416 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03417 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
EKFEBFEA_03418 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EKFEBFEA_03419 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EKFEBFEA_03420 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EKFEBFEA_03421 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EKFEBFEA_03422 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EKFEBFEA_03423 3.28e-151 yuiC - - S - - - protein conserved in bacteria
EKFEBFEA_03424 9.78e-47 yuiB - - S - - - Putative membrane protein
EKFEBFEA_03425 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EKFEBFEA_03426 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EKFEBFEA_03428 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKFEBFEA_03429 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
EKFEBFEA_03430 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_03431 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EKFEBFEA_03432 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKFEBFEA_03433 1.54e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFEBFEA_03434 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EKFEBFEA_03435 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EKFEBFEA_03436 6.61e-75 yuzD - - S - - - protein conserved in bacteria
EKFEBFEA_03437 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EKFEBFEA_03438 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EKFEBFEA_03439 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EKFEBFEA_03440 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EKFEBFEA_03441 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EKFEBFEA_03442 4.63e-255 yutH - - S - - - Spore coat protein
EKFEBFEA_03443 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EKFEBFEA_03444 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EKFEBFEA_03445 9.69e-99 yutE - - S - - - Protein of unknown function DUF86
EKFEBFEA_03446 3.2e-63 yutD - - S - - - protein conserved in bacteria
EKFEBFEA_03447 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EKFEBFEA_03448 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EKFEBFEA_03449 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EKFEBFEA_03450 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EKFEBFEA_03451 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
EKFEBFEA_03452 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EKFEBFEA_03453 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EKFEBFEA_03454 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
EKFEBFEA_03455 2.72e-82 yunG - - - - - - -
EKFEBFEA_03456 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EKFEBFEA_03457 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EKFEBFEA_03458 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
EKFEBFEA_03459 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EKFEBFEA_03460 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EKFEBFEA_03461 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EKFEBFEA_03462 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EKFEBFEA_03463 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EKFEBFEA_03464 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EKFEBFEA_03465 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EKFEBFEA_03466 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EKFEBFEA_03468 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EKFEBFEA_03469 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EKFEBFEA_03470 6.53e-218 bsn - - L - - - Ribonuclease
EKFEBFEA_03471 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_03472 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EKFEBFEA_03473 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EKFEBFEA_03474 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EKFEBFEA_03475 1.24e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EKFEBFEA_03476 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EKFEBFEA_03477 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EKFEBFEA_03478 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EKFEBFEA_03479 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EKFEBFEA_03481 3.35e-56 - - - - - - - -
EKFEBFEA_03482 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_03483 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EKFEBFEA_03484 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EKFEBFEA_03485 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKFEBFEA_03486 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EKFEBFEA_03487 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EKFEBFEA_03488 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKFEBFEA_03489 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EKFEBFEA_03490 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EKFEBFEA_03491 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKFEBFEA_03492 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
EKFEBFEA_03493 2e-73 yusE - - CO - - - Thioredoxin
EKFEBFEA_03494 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EKFEBFEA_03495 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EKFEBFEA_03496 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EKFEBFEA_03497 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EKFEBFEA_03498 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EKFEBFEA_03499 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EKFEBFEA_03500 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EKFEBFEA_03501 2.86e-14 - - - S - - - YuzL-like protein
EKFEBFEA_03502 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EKFEBFEA_03503 2.23e-54 - - - - - - - -
EKFEBFEA_03504 2.12e-70 yusN - - M - - - Coat F domain
EKFEBFEA_03505 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EKFEBFEA_03506 0.0 yusP - - P - - - Major facilitator superfamily
EKFEBFEA_03507 1.76e-86 yusQ - - S - - - Tautomerase enzyme
EKFEBFEA_03508 6.81e-82 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03509 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03510 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EKFEBFEA_03511 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
EKFEBFEA_03512 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EKFEBFEA_03513 2.01e-87 - - - S - - - YusW-like protein
EKFEBFEA_03514 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EKFEBFEA_03515 1.21e-41 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EKFEBFEA_03516 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03517 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
EKFEBFEA_03518 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFEBFEA_03519 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_03520 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03521 3.06e-204 yuxN - - K - - - Transcriptional regulator
EKFEBFEA_03522 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EKFEBFEA_03523 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
EKFEBFEA_03524 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EKFEBFEA_03525 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EKFEBFEA_03526 1.22e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EKFEBFEA_03527 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_03528 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03529 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EKFEBFEA_03530 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EKFEBFEA_03531 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EKFEBFEA_03532 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EKFEBFEA_03533 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_03534 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EKFEBFEA_03535 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EKFEBFEA_03536 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_03537 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EKFEBFEA_03538 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03539 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EKFEBFEA_03540 0.0 yvrG - - T - - - Histidine kinase
EKFEBFEA_03541 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_03542 5.07e-32 - - - - - - - -
EKFEBFEA_03543 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EKFEBFEA_03544 3.46e-26 - - - S - - - YvrJ protein family
EKFEBFEA_03545 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EKFEBFEA_03546 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
EKFEBFEA_03547 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EKFEBFEA_03548 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03549 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
EKFEBFEA_03550 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EKFEBFEA_03551 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_03552 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKFEBFEA_03553 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_03555 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EKFEBFEA_03556 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EKFEBFEA_03557 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EKFEBFEA_03558 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EKFEBFEA_03559 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EKFEBFEA_03560 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EKFEBFEA_03561 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EKFEBFEA_03562 4.54e-203 yvgN - - S - - - reductase
EKFEBFEA_03563 7.97e-113 yvgO - - - - - - -
EKFEBFEA_03564 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EKFEBFEA_03565 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EKFEBFEA_03566 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EKFEBFEA_03567 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EKFEBFEA_03568 3.88e-140 yvgT - - S - - - membrane
EKFEBFEA_03569 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EKFEBFEA_03570 3.45e-137 bdbD - - O - - - Thioredoxin
EKFEBFEA_03571 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EKFEBFEA_03572 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EKFEBFEA_03573 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
EKFEBFEA_03574 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EKFEBFEA_03575 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EKFEBFEA_03576 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EKFEBFEA_03577 0.0 - - - S - - - Fusaric acid resistance protein-like
EKFEBFEA_03578 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
EKFEBFEA_03579 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EKFEBFEA_03580 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
EKFEBFEA_03581 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_03583 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EKFEBFEA_03584 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EKFEBFEA_03585 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EKFEBFEA_03586 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EKFEBFEA_03587 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
EKFEBFEA_03588 3.44e-48 yvzC - - K - - - transcriptional
EKFEBFEA_03589 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EKFEBFEA_03590 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EKFEBFEA_03591 3.85e-72 yvaP - - K - - - transcriptional
EKFEBFEA_03592 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EKFEBFEA_03593 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFEBFEA_03594 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKFEBFEA_03595 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFEBFEA_03596 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKFEBFEA_03597 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EKFEBFEA_03598 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
EKFEBFEA_03599 4.79e-224 - - - - - - - -
EKFEBFEA_03601 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EKFEBFEA_03602 9.63e-60 sdpR - - K - - - transcriptional
EKFEBFEA_03603 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFEBFEA_03604 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EKFEBFEA_03605 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EKFEBFEA_03606 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EKFEBFEA_03607 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EKFEBFEA_03608 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EKFEBFEA_03609 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
EKFEBFEA_03610 2.38e-158 yvbI - - M - - - Membrane
EKFEBFEA_03611 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EKFEBFEA_03612 2.4e-106 yvbK - - K - - - acetyltransferase
EKFEBFEA_03613 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EKFEBFEA_03614 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EKFEBFEA_03615 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKFEBFEA_03616 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EKFEBFEA_03617 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKFEBFEA_03618 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKFEBFEA_03619 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_03620 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EKFEBFEA_03621 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_03622 3.45e-206 yvbU - - K - - - Transcriptional regulator
EKFEBFEA_03623 2.37e-199 yvbV - - EG - - - EamA-like transporter family
EKFEBFEA_03624 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EKFEBFEA_03625 2.68e-252 - - - S - - - Glycosyl hydrolase
EKFEBFEA_03626 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKFEBFEA_03627 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EKFEBFEA_03628 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EKFEBFEA_03629 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_03630 1.76e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_03631 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EKFEBFEA_03632 1.03e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EKFEBFEA_03633 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
EKFEBFEA_03634 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
EKFEBFEA_03635 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EKFEBFEA_03636 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
EKFEBFEA_03637 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EKFEBFEA_03638 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EKFEBFEA_03639 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EKFEBFEA_03640 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_03641 9.32e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EKFEBFEA_03642 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EKFEBFEA_03643 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EKFEBFEA_03644 5.69e-44 yvfG - - S - - - YvfG protein
EKFEBFEA_03645 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EKFEBFEA_03646 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EKFEBFEA_03647 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EKFEBFEA_03648 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKFEBFEA_03649 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_03650 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_03651 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EKFEBFEA_03652 6.3e-251 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EKFEBFEA_03653 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EKFEBFEA_03654 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EKFEBFEA_03655 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EKFEBFEA_03656 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EKFEBFEA_03657 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EKFEBFEA_03658 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EKFEBFEA_03659 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EKFEBFEA_03660 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EKFEBFEA_03661 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EKFEBFEA_03663 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EKFEBFEA_03664 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
EKFEBFEA_03665 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EKFEBFEA_03666 0.0 pbpE - - V - - - Beta-lactamase
EKFEBFEA_03667 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EKFEBFEA_03668 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EKFEBFEA_03669 0.0 ybeC - - E - - - amino acid
EKFEBFEA_03670 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
EKFEBFEA_03671 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EKFEBFEA_03672 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EKFEBFEA_03673 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
EKFEBFEA_03674 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EKFEBFEA_03675 1.99e-235 - - - S - - - Patatin-like phospholipase
EKFEBFEA_03677 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EKFEBFEA_03678 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EKFEBFEA_03679 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EKFEBFEA_03680 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
EKFEBFEA_03681 2.42e-203 malA - - S - - - Protein of unknown function (DUF1189)
EKFEBFEA_03682 1.18e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EKFEBFEA_03683 2.12e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EKFEBFEA_03684 1.03e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EKFEBFEA_03685 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
EKFEBFEA_03686 2.28e-223 yvdE - - K - - - Transcriptional regulator
EKFEBFEA_03687 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EKFEBFEA_03688 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EKFEBFEA_03689 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EKFEBFEA_03690 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EKFEBFEA_03691 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKFEBFEA_03692 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EKFEBFEA_03693 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_03694 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
EKFEBFEA_03695 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_03696 1.37e-45 - - - - - - - -
EKFEBFEA_03697 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EKFEBFEA_03698 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EKFEBFEA_03699 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EKFEBFEA_03700 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EKFEBFEA_03701 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EKFEBFEA_03702 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EKFEBFEA_03703 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EKFEBFEA_03704 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EKFEBFEA_03705 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EKFEBFEA_03706 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EKFEBFEA_03708 0.0 - - - - - - - -
EKFEBFEA_03709 6.36e-172 - - - - - - - -
EKFEBFEA_03710 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EKFEBFEA_03711 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EKFEBFEA_03712 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EKFEBFEA_03713 7.21e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKFEBFEA_03714 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EKFEBFEA_03715 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EKFEBFEA_03716 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EKFEBFEA_03717 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EKFEBFEA_03718 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
EKFEBFEA_03719 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
EKFEBFEA_03720 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EKFEBFEA_03721 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EKFEBFEA_03722 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
EKFEBFEA_03723 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKFEBFEA_03724 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKFEBFEA_03725 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKFEBFEA_03726 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EKFEBFEA_03727 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EKFEBFEA_03728 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EKFEBFEA_03729 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_03730 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EKFEBFEA_03731 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EKFEBFEA_03732 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_03733 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
EKFEBFEA_03734 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EKFEBFEA_03735 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EKFEBFEA_03736 5.8e-221 yvlB - - S - - - Putative adhesin
EKFEBFEA_03737 8.09e-65 yvlA - - - - - - -
EKFEBFEA_03738 2.73e-46 yvkN - - - - - - -
EKFEBFEA_03739 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKFEBFEA_03740 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EKFEBFEA_03741 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EKFEBFEA_03742 2.54e-42 csbA - - S - - - protein conserved in bacteria
EKFEBFEA_03743 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EKFEBFEA_03744 1.43e-131 yvkB - - K - - - Transcriptional regulator
EKFEBFEA_03745 5.47e-298 yvkA - - P - - - -transporter
EKFEBFEA_03746 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFEBFEA_03747 1.68e-72 swrA - - S - - - Swarming motility protein
EKFEBFEA_03748 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EKFEBFEA_03749 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EKFEBFEA_03750 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EKFEBFEA_03751 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EKFEBFEA_03752 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EKFEBFEA_03753 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKFEBFEA_03754 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EKFEBFEA_03755 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKFEBFEA_03756 9.14e-88 - - - - - - - -
EKFEBFEA_03757 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EKFEBFEA_03758 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EKFEBFEA_03759 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EKFEBFEA_03760 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
EKFEBFEA_03761 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EKFEBFEA_03762 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EKFEBFEA_03763 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EKFEBFEA_03764 4.19e-93 yviE - - - - - - -
EKFEBFEA_03765 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EKFEBFEA_03766 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EKFEBFEA_03767 3.5e-102 yvyG - - NOU - - - FlgN protein
EKFEBFEA_03768 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EKFEBFEA_03769 1.83e-96 yvyF - - S - - - flagellar protein
EKFEBFEA_03770 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EKFEBFEA_03771 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EKFEBFEA_03772 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EKFEBFEA_03773 2.15e-199 degV - - S - - - protein conserved in bacteria
EKFEBFEA_03774 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EKFEBFEA_03775 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EKFEBFEA_03776 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EKFEBFEA_03777 3.99e-225 yvhJ - - K - - - Transcriptional regulator
EKFEBFEA_03778 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EKFEBFEA_03779 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EKFEBFEA_03780 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EKFEBFEA_03781 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EKFEBFEA_03782 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EKFEBFEA_03783 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFEBFEA_03784 8.77e-283 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EKFEBFEA_03785 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EKFEBFEA_03786 6.49e-100 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EKFEBFEA_03787 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EKFEBFEA_03788 0.0 lytB - - D - - - Stage II sporulation protein
EKFEBFEA_03789 3.26e-50 - - - - - - - -
EKFEBFEA_03790 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EKFEBFEA_03791 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EKFEBFEA_03792 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EKFEBFEA_03793 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EKFEBFEA_03794 0.0 - - - M - - - Glycosyltransferase like family 2
EKFEBFEA_03795 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
EKFEBFEA_03796 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EKFEBFEA_03797 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EKFEBFEA_03798 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EKFEBFEA_03799 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKFEBFEA_03800 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
EKFEBFEA_03801 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EKFEBFEA_03802 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EKFEBFEA_03803 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EKFEBFEA_03804 0.0 - - - - - - - -
EKFEBFEA_03805 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKFEBFEA_03806 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EKFEBFEA_03807 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EKFEBFEA_03808 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EKFEBFEA_03809 2.29e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EKFEBFEA_03810 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_03811 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
EKFEBFEA_03812 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EKFEBFEA_03813 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EKFEBFEA_03814 2.29e-29 ywtC - - - - - - -
EKFEBFEA_03815 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EKFEBFEA_03816 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EKFEBFEA_03817 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EKFEBFEA_03818 2.92e-231 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
EKFEBFEA_03819 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKFEBFEA_03820 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EKFEBFEA_03821 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EKFEBFEA_03822 2.87e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EKFEBFEA_03823 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EKFEBFEA_03824 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
EKFEBFEA_03825 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
EKFEBFEA_03826 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EKFEBFEA_03827 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EKFEBFEA_03828 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EKFEBFEA_03829 3.36e-218 alsR - - K - - - LysR substrate binding domain
EKFEBFEA_03830 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EKFEBFEA_03831 9.09e-164 ywrJ - - - - - - -
EKFEBFEA_03832 1.02e-196 cotB - - - ko:K06325 - ko00000 -
EKFEBFEA_03833 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
EKFEBFEA_03834 2.17e-16 - - - - - - - -
EKFEBFEA_03835 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EKFEBFEA_03836 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
EKFEBFEA_03837 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EKFEBFEA_03838 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EKFEBFEA_03839 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EKFEBFEA_03840 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EKFEBFEA_03842 3.83e-132 ywqN - - S - - - NAD(P)H-dependent
EKFEBFEA_03843 1.16e-209 - - - K - - - Transcriptional regulator
EKFEBFEA_03844 7.78e-176 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EKFEBFEA_03845 1.36e-71 - - - S - - - MORN repeat variant
EKFEBFEA_03846 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
EKFEBFEA_03847 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
EKFEBFEA_03849 2.52e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
EKFEBFEA_03850 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKFEBFEA_03851 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EKFEBFEA_03852 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EKFEBFEA_03853 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EKFEBFEA_03854 3.6e-25 - - - - - - - -
EKFEBFEA_03855 0.0 ywqB - - S - - - SWIM zinc finger
EKFEBFEA_03856 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EKFEBFEA_03857 4.53e-203 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EKFEBFEA_03858 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EKFEBFEA_03859 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EKFEBFEA_03860 5.26e-88 ywpG - - - - - - -
EKFEBFEA_03861 8.81e-89 ywpF - - S - - - YwpF-like protein
EKFEBFEA_03862 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EKFEBFEA_03863 2.55e-197 ywpD - - T - - - Histidine kinase
EKFEBFEA_03864 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EKFEBFEA_03865 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKFEBFEA_03866 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EKFEBFEA_03867 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EKFEBFEA_03868 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EKFEBFEA_03869 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EKFEBFEA_03870 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EKFEBFEA_03871 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
EKFEBFEA_03872 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_03873 1.02e-312 ywoF - - P - - - Right handed beta helix region
EKFEBFEA_03874 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EKFEBFEA_03875 8e-309 ywoD - - EGP - - - Major facilitator superfamily
EKFEBFEA_03876 2.56e-134 yjgF - - Q - - - Isochorismatase family
EKFEBFEA_03877 3.04e-102 - - - - - - - -
EKFEBFEA_03878 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EKFEBFEA_03879 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EKFEBFEA_03880 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EKFEBFEA_03881 1.63e-95 ywnJ - - S - - - VanZ like family
EKFEBFEA_03882 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EKFEBFEA_03883 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EKFEBFEA_03884 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
EKFEBFEA_03885 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
EKFEBFEA_03886 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKFEBFEA_03887 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EKFEBFEA_03888 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
EKFEBFEA_03889 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EKFEBFEA_03890 4.58e-85 ywnA - - K - - - Transcriptional regulator
EKFEBFEA_03891 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EKFEBFEA_03892 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EKFEBFEA_03893 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EKFEBFEA_03895 1.11e-21 csbD - - K - - - CsbD-like
EKFEBFEA_03896 1.12e-109 ywmF - - S - - - Peptidase M50
EKFEBFEA_03897 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EKFEBFEA_03898 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKFEBFEA_03899 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EKFEBFEA_03901 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EKFEBFEA_03902 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EKFEBFEA_03903 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EKFEBFEA_03904 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKFEBFEA_03905 2.39e-174 ywmB - - S - - - TATA-box binding
EKFEBFEA_03906 4.54e-45 ywzB - - S - - - membrane
EKFEBFEA_03907 6.12e-115 ywmA - - - - - - -
EKFEBFEA_03908 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EKFEBFEA_03909 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKFEBFEA_03910 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKFEBFEA_03911 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKFEBFEA_03912 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKFEBFEA_03913 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKFEBFEA_03914 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKFEBFEA_03915 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EKFEBFEA_03916 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EKFEBFEA_03917 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKFEBFEA_03918 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKFEBFEA_03919 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
EKFEBFEA_03920 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EKFEBFEA_03921 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKFEBFEA_03922 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
EKFEBFEA_03923 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EKFEBFEA_03924 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EKFEBFEA_03925 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EKFEBFEA_03926 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EKFEBFEA_03928 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EKFEBFEA_03929 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKFEBFEA_03930 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_03931 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EKFEBFEA_03932 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EKFEBFEA_03933 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EKFEBFEA_03934 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EKFEBFEA_03935 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EKFEBFEA_03936 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKFEBFEA_03937 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EKFEBFEA_03938 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKFEBFEA_03939 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EKFEBFEA_03940 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EKFEBFEA_03941 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EKFEBFEA_03942 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
EKFEBFEA_03943 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EKFEBFEA_03944 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EKFEBFEA_03945 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
EKFEBFEA_03946 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EKFEBFEA_03947 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EKFEBFEA_03948 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EKFEBFEA_03949 1.32e-57 ywjC - - - - - - -
EKFEBFEA_03950 1.35e-124 ywjB - - H - - - RibD C-terminal domain
EKFEBFEA_03951 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EKFEBFEA_03952 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKFEBFEA_03953 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EKFEBFEA_03954 6.32e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EKFEBFEA_03955 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EKFEBFEA_03956 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFEBFEA_03957 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EKFEBFEA_03958 1.57e-180 ywiC - - S - - - YwiC-like protein
EKFEBFEA_03959 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EKFEBFEA_03960 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EKFEBFEA_03961 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EKFEBFEA_03962 4.64e-96 ywiB - - S - - - protein conserved in bacteria
EKFEBFEA_03963 3.71e-12 - - - S - - - Bacteriocin subtilosin A
EKFEBFEA_03964 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
EKFEBFEA_03966 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EKFEBFEA_03967 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EKFEBFEA_03968 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
EKFEBFEA_03969 0.0 - - - L - - - Peptidase, M16
EKFEBFEA_03971 0.0 ywhL - - CO - - - amine dehydrogenase activity
EKFEBFEA_03972 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
EKFEBFEA_03973 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EKFEBFEA_03975 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
EKFEBFEA_03976 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EKFEBFEA_03977 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EKFEBFEA_03978 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EKFEBFEA_03979 1.92e-123 ywhD - - S - - - YwhD family
EKFEBFEA_03980 3.29e-154 ywhC - - S - - - Peptidase family M50
EKFEBFEA_03981 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EKFEBFEA_03982 1.76e-94 ywhA - - K - - - Transcriptional regulator
EKFEBFEA_03983 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKFEBFEA_03985 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
EKFEBFEA_03986 1.1e-103 yffB - - K - - - Transcriptional regulator
EKFEBFEA_03987 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
EKFEBFEA_03988 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EKFEBFEA_03989 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EKFEBFEA_03990 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EKFEBFEA_03991 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
EKFEBFEA_03992 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EKFEBFEA_03993 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_03994 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EKFEBFEA_03995 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EKFEBFEA_03996 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_03997 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EKFEBFEA_03998 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EKFEBFEA_03999 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EKFEBFEA_04000 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKFEBFEA_04001 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EKFEBFEA_04002 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EKFEBFEA_04003 1.89e-275 ywfA - - EGP - - - -transporter
EKFEBFEA_04004 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EKFEBFEA_04005 0.0 rocB - - E - - - arginine degradation protein
EKFEBFEA_04006 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EKFEBFEA_04007 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EKFEBFEA_04008 1.1e-102 - - - - - - - -
EKFEBFEA_04009 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EKFEBFEA_04010 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EKFEBFEA_04011 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EKFEBFEA_04012 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EKFEBFEA_04013 2.54e-243 spsG - - M - - - Spore Coat
EKFEBFEA_04014 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
EKFEBFEA_04015 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EKFEBFEA_04016 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EKFEBFEA_04017 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EKFEBFEA_04018 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EKFEBFEA_04019 4.87e-188 spsA - - M - - - Spore Coat
EKFEBFEA_04020 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EKFEBFEA_04021 1.59e-78 ywdK - - S - - - small membrane protein
EKFEBFEA_04022 4.57e-304 ywdJ - - F - - - Xanthine uracil
EKFEBFEA_04023 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
EKFEBFEA_04024 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EKFEBFEA_04025 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKFEBFEA_04026 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
EKFEBFEA_04028 8.74e-146 ywdD - - - - - - -
EKFEBFEA_04029 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
EKFEBFEA_04030 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EKFEBFEA_04031 6.19e-39 ywdA - - - - - - -
EKFEBFEA_04032 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EKFEBFEA_04033 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_04034 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
EKFEBFEA_04035 4.49e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EKFEBFEA_04037 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EKFEBFEA_04038 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_04039 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EKFEBFEA_04040 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EKFEBFEA_04041 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EKFEBFEA_04042 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EKFEBFEA_04043 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EKFEBFEA_04044 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EKFEBFEA_04045 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EKFEBFEA_04046 5.11e-49 ydaS - - S - - - membrane
EKFEBFEA_04047 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EKFEBFEA_04048 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKFEBFEA_04049 3.33e-77 gtcA - - S - - - GtrA-like protein
EKFEBFEA_04050 4.16e-159 ywcC - - K - - - transcriptional regulator
EKFEBFEA_04052 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
EKFEBFEA_04053 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKFEBFEA_04054 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EKFEBFEA_04055 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EKFEBFEA_04056 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
EKFEBFEA_04057 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
EKFEBFEA_04058 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EKFEBFEA_04059 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EKFEBFEA_04060 2.7e-203 ywbI - - K - - - Transcriptional regulator
EKFEBFEA_04061 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EKFEBFEA_04062 1.21e-143 ywbG - - M - - - effector of murein hydrolase
EKFEBFEA_04063 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
EKFEBFEA_04064 1.32e-39 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EKFEBFEA_04065 1.3e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EKFEBFEA_04066 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EKFEBFEA_04067 7.78e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
EKFEBFEA_04068 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFEBFEA_04069 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EKFEBFEA_04070 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_04071 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EKFEBFEA_04072 6.53e-217 gspA - - M - - - General stress
EKFEBFEA_04073 3.96e-164 ywaF - - S - - - Integral membrane protein
EKFEBFEA_04074 2.15e-115 ywaE - - K - - - Transcriptional regulator
EKFEBFEA_04075 2.7e-298 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKFEBFEA_04076 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EKFEBFEA_04077 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EKFEBFEA_04078 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EKFEBFEA_04079 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
EKFEBFEA_04080 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_04081 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EKFEBFEA_04082 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKFEBFEA_04083 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKFEBFEA_04084 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_04085 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EKFEBFEA_04086 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EKFEBFEA_04087 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_04088 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKFEBFEA_04089 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EKFEBFEA_04090 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EKFEBFEA_04091 8.94e-28 yxzF - - - - - - -
EKFEBFEA_04092 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EKFEBFEA_04093 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EKFEBFEA_04094 4.48e-277 yxlH - - EGP - - - Major Facilitator Superfamily
EKFEBFEA_04095 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EKFEBFEA_04096 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_04097 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
EKFEBFEA_04098 1.75e-43 - - - - - - - -
EKFEBFEA_04099 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
EKFEBFEA_04100 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EKFEBFEA_04101 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EKFEBFEA_04102 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKFEBFEA_04103 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EKFEBFEA_04104 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EKFEBFEA_04105 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EKFEBFEA_04106 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EKFEBFEA_04107 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
EKFEBFEA_04108 0.0 - - - O - - - Peptidase family M48
EKFEBFEA_04110 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
EKFEBFEA_04111 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EKFEBFEA_04112 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EKFEBFEA_04113 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFEBFEA_04114 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKFEBFEA_04115 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
EKFEBFEA_04116 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EKFEBFEA_04117 2.01e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EKFEBFEA_04118 1.53e-213 - - - K - - - LysR substrate binding domain
EKFEBFEA_04119 5.63e-102 - - - S - - - Protein of unknown function (DUF1453)
EKFEBFEA_04120 7.13e-261 - - - T - - - Signal transduction histidine kinase
EKFEBFEA_04121 5.66e-150 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
EKFEBFEA_04122 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EKFEBFEA_04125 2.57e-114 yxjI - - S - - - LURP-one-related
EKFEBFEA_04126 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EKFEBFEA_04127 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EKFEBFEA_04128 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EKFEBFEA_04129 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EKFEBFEA_04130 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EKFEBFEA_04131 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EKFEBFEA_04132 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EKFEBFEA_04133 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFEBFEA_04134 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
EKFEBFEA_04135 9.65e-65 yxiS - - - - - - -
EKFEBFEA_04136 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EKFEBFEA_04137 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EKFEBFEA_04138 2.62e-185 bglS - - M - - - licheninase activity
EKFEBFEA_04139 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EKFEBFEA_04140 2.75e-145 - - - - - - - -
EKFEBFEA_04141 3.97e-294 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EKFEBFEA_04142 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EKFEBFEA_04143 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
EKFEBFEA_04146 5.53e-65 yxiJ - - S - - - YxiJ-like protein
EKFEBFEA_04147 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
EKFEBFEA_04148 6.22e-107 - - - - - - - -
EKFEBFEA_04149 1.2e-57 - - - - - - - -
EKFEBFEA_04150 8.76e-99 yxiG - - - - - - -
EKFEBFEA_04151 1.12e-82 - - - - - - - -
EKFEBFEA_04152 3.69e-111 - - - - - - - -
EKFEBFEA_04153 1.09e-94 yxxG - - - - - - -
EKFEBFEA_04154 0.0 wapA - - M - - - COG3209 Rhs family protein
EKFEBFEA_04155 1.17e-216 yxxF - - EG - - - EamA-like transporter family
EKFEBFEA_04156 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
EKFEBFEA_04157 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EKFEBFEA_04158 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_04159 1.33e-67 - - - - - - - -
EKFEBFEA_04160 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
EKFEBFEA_04161 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
EKFEBFEA_04162 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
EKFEBFEA_04163 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
EKFEBFEA_04164 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EKFEBFEA_04165 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EKFEBFEA_04166 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EKFEBFEA_04167 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EKFEBFEA_04168 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EKFEBFEA_04169 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EKFEBFEA_04170 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EKFEBFEA_04171 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EKFEBFEA_04172 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EKFEBFEA_04173 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKFEBFEA_04174 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EKFEBFEA_04175 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
EKFEBFEA_04176 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
EKFEBFEA_04177 0.0 yxeQ - - S - - - MmgE/PrpD family
EKFEBFEA_04178 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EKFEBFEA_04179 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_04180 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EKFEBFEA_04181 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EKFEBFEA_04182 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKFEBFEA_04183 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EKFEBFEA_04185 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EKFEBFEA_04186 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
EKFEBFEA_04189 7.32e-42 yxeE - - - - - - -
EKFEBFEA_04190 2.66e-28 yxeD - - - - - - -
EKFEBFEA_04191 6.79e-91 - - - - - - - -
EKFEBFEA_04192 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_04193 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
EKFEBFEA_04194 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EKFEBFEA_04195 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EKFEBFEA_04196 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_04197 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_04198 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EKFEBFEA_04199 9.32e-188 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EKFEBFEA_04200 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EKFEBFEA_04201 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EKFEBFEA_04202 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EKFEBFEA_04203 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EKFEBFEA_04204 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EKFEBFEA_04205 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EKFEBFEA_04206 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EKFEBFEA_04207 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EKFEBFEA_04208 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EKFEBFEA_04209 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EKFEBFEA_04211 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
EKFEBFEA_04212 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKFEBFEA_04213 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EKFEBFEA_04215 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EKFEBFEA_04216 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EKFEBFEA_04217 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EKFEBFEA_04218 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
EKFEBFEA_04219 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
EKFEBFEA_04220 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
EKFEBFEA_04221 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
EKFEBFEA_04222 8.99e-114 yxnB - - - - - - -
EKFEBFEA_04223 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EKFEBFEA_04224 1.8e-271 yxaM - - U - - - MFS_1 like family
EKFEBFEA_04225 2.63e-137 yxaL - - S - - - PQQ-like domain
EKFEBFEA_04226 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
EKFEBFEA_04227 2.83e-99 yxaI - - S - - - membrane protein domain
EKFEBFEA_04228 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EKFEBFEA_04229 9.33e-254 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
EKFEBFEA_04230 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EKFEBFEA_04231 4.48e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EKFEBFEA_04232 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EKFEBFEA_04233 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EKFEBFEA_04234 2.19e-153 yxaC - - M - - - effector of murein hydrolase
EKFEBFEA_04235 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
EKFEBFEA_04236 2.54e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EKFEBFEA_04237 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
EKFEBFEA_04238 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EKFEBFEA_04239 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EKFEBFEA_04240 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKFEBFEA_04241 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EKFEBFEA_04242 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EKFEBFEA_04243 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EKFEBFEA_04244 1.2e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EKFEBFEA_04245 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EKFEBFEA_04246 1.44e-24 - - - - - - - -
EKFEBFEA_04247 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EKFEBFEA_04248 5.06e-144 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EKFEBFEA_04249 1.55e-173 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
EKFEBFEA_04250 1.35e-237 - - - S - - - Radical SAM superfamily
EKFEBFEA_04251 1.99e-17 - - - - - - - -
EKFEBFEA_04252 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EKFEBFEA_04253 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
EKFEBFEA_04254 7.17e-86 - - - - - - - -
EKFEBFEA_04255 0.0 - - - S - - - Calcineurin-like phosphoesterase
EKFEBFEA_04256 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKFEBFEA_04258 1.25e-93 - - - - - - - -
EKFEBFEA_04259 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EKFEBFEA_04261 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
EKFEBFEA_04262 1.77e-281 yycP - - - - - - -
EKFEBFEA_04263 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EKFEBFEA_04264 3.84e-113 yycN - - K - - - Acetyltransferase
EKFEBFEA_04265 3.03e-239 - - - S - - - aspartate phosphatase
EKFEBFEA_04267 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EKFEBFEA_04268 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EKFEBFEA_04269 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EKFEBFEA_04270 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EKFEBFEA_04271 2.42e-281 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EKFEBFEA_04272 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EKFEBFEA_04273 1.2e-200 yycI - - S - - - protein conserved in bacteria
EKFEBFEA_04274 0.0 yycH - - S - - - protein conserved in bacteria
EKFEBFEA_04275 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EKFEBFEA_04276 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EKFEBFEA_04281 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKFEBFEA_04282 1.19e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_04283 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EKFEBFEA_04284 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EKFEBFEA_04286 1.89e-22 yycC - - K - - - YycC-like protein
EKFEBFEA_04287 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EKFEBFEA_04288 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKFEBFEA_04289 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EKFEBFEA_04290 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EKFEBFEA_04291 5.23e-205 yybS - - S - - - membrane
EKFEBFEA_04293 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
EKFEBFEA_04294 6.68e-90 yybR - - K - - - Transcriptional regulator
EKFEBFEA_04295 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EKFEBFEA_04296 2.34e-92 - - - - - - - -
EKFEBFEA_04298 6.8e-308 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_04299 3.44e-22 - - - - - - - -
EKFEBFEA_04300 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
EKFEBFEA_04301 3.78e-169 - - - - - - - -
EKFEBFEA_04302 5.36e-157 - - - - - - - -
EKFEBFEA_04303 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
EKFEBFEA_04304 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EKFEBFEA_04305 4.35e-194 - - - - - - - -
EKFEBFEA_04306 3.02e-88 - - - S - - - SnoaL-like domain
EKFEBFEA_04307 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
EKFEBFEA_04308 3.31e-281 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_04309 1.36e-212 yybE - - K - - - Transcriptional regulator
EKFEBFEA_04310 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
EKFEBFEA_04311 1.27e-99 yybC - - - - - - -
EKFEBFEA_04312 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
EKFEBFEA_04313 4.54e-100 yybA - - K - - - transcriptional
EKFEBFEA_04314 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
EKFEBFEA_04315 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
EKFEBFEA_04316 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EKFEBFEA_04317 1.09e-87 - - - S - - - YjbR
EKFEBFEA_04318 2.2e-139 yyaP - - H - - - RibD C-terminal domain
EKFEBFEA_04319 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EKFEBFEA_04320 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
EKFEBFEA_04321 1.34e-88 - - - K - - - MerR HTH family regulatory protein
EKFEBFEA_04322 1.99e-207 - - - EG - - - EamA-like transporter family
EKFEBFEA_04323 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EKFEBFEA_04324 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EKFEBFEA_04325 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
EKFEBFEA_04326 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EKFEBFEA_04327 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKFEBFEA_04328 3.03e-230 ccpB - - K - - - Transcriptional regulator
EKFEBFEA_04329 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EKFEBFEA_04330 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKFEBFEA_04331 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKFEBFEA_04332 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EKFEBFEA_04333 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EKFEBFEA_04334 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EKFEBFEA_04335 7.41e-45 yyzM - - S - - - protein conserved in bacteria
EKFEBFEA_04336 5.34e-227 yyaD - - S - - - Membrane
EKFEBFEA_04337 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
EKFEBFEA_04338 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EKFEBFEA_04339 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EKFEBFEA_04340 1.13e-98 - - - S - - - Bacterial PH domain
EKFEBFEA_04341 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EKFEBFEA_04342 8.68e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EKFEBFEA_04343 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EKFEBFEA_04344 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKFEBFEA_04345 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EKFEBFEA_04346 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKFEBFEA_04347 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)