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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MDFAHGHL_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDFAHGHL_00002	3.45e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDFAHGHL_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MDFAHGHL_00004	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDFAHGHL_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MDFAHGHL_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDFAHGHL_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDFAHGHL_00008	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MDFAHGHL_00009	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDFAHGHL_00010	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MDFAHGHL_00011	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDFAHGHL_00012	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDFAHGHL_00013	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00016	1e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
MDFAHGHL_00017	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDFAHGHL_00018	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDFAHGHL_00019	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDFAHGHL_00020	2.35e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDFAHGHL_00021	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDFAHGHL_00022	4.17e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MDFAHGHL_00024	1.25e-157	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MDFAHGHL_00025	4.04e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MDFAHGHL_00026	1.44e-277	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MDFAHGHL_00027	1.01e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MDFAHGHL_00028	2.48e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDFAHGHL_00029	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDFAHGHL_00030	2.41e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDFAHGHL_00031	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDFAHGHL_00032	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MDFAHGHL_00033	1.07e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MDFAHGHL_00034	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00037	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MDFAHGHL_00038	1.45e-136	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MDFAHGHL_00039	2.17e-247	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MDFAHGHL_00040	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MDFAHGHL_00041	1.9e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDFAHGHL_00042	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00043	2.86e-92	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MDFAHGHL_00044	1.56e-232	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDFAHGHL_00045	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MDFAHGHL_00046	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MDFAHGHL_00047	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MDFAHGHL_00048	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MDFAHGHL_00049	3.33e-209	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDFAHGHL_00050	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MDFAHGHL_00051	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDFAHGHL_00052	2.09e-22	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDFAHGHL_00053	4.31e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MDFAHGHL_00054	2.49e-310	yabE	-	-	T	-	-	-	protein conserved in bacteria
MDFAHGHL_00055	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDFAHGHL_00056	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDFAHGHL_00057	8.17e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MDFAHGHL_00058	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00059	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MDFAHGHL_00060	2.73e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDFAHGHL_00061	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MDFAHGHL_00062	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MDFAHGHL_00063	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MDFAHGHL_00064	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDFAHGHL_00065	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDFAHGHL_00066	3.72e-138	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDFAHGHL_00067	5.18e-07	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDFAHGHL_00068	7.82e-118	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDFAHGHL_00069	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MDFAHGHL_00070	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDFAHGHL_00071	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MDFAHGHL_00072	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_00073	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MDFAHGHL_00074	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MDFAHGHL_00075	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MDFAHGHL_00076	9.16e-65	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MDFAHGHL_00077	1.2e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MDFAHGHL_00078	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MDFAHGHL_00081	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MDFAHGHL_00082	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDFAHGHL_00083	1.15e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDFAHGHL_00084	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDFAHGHL_00085	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDFAHGHL_00086	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDFAHGHL_00087	1.15e-187	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDFAHGHL_00088	4.53e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDFAHGHL_00089	1.29e-203	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MDFAHGHL_00090	4.4e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDFAHGHL_00091	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDFAHGHL_00092	1.31e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MDFAHGHL_00093	3.6e-209	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MDFAHGHL_00094	4.92e-184	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDFAHGHL_00095	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDFAHGHL_00096	8.2e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MDFAHGHL_00097	1.44e-38	yazB	-	-	K	-	-	-	transcriptional
MDFAHGHL_00098	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDFAHGHL_00099	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MDFAHGHL_00100	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00110	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00111	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MDFAHGHL_00112	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MDFAHGHL_00113	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MDFAHGHL_00114	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MDFAHGHL_00116	6.35e-156	lcnDR2	-	-	V	-	-	-	Domain of unknown function (DUF4135)
MDFAHGHL_00117	4.97e-164	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MDFAHGHL_00118	1.65e-61	-	-	-	O	ko:K20486	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S8 family
MDFAHGHL_00119	4.4e-22	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDFAHGHL_00120	4.01e-257	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDFAHGHL_00121	7.66e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MDFAHGHL_00122	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MDFAHGHL_00123	3.02e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDFAHGHL_00124	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDFAHGHL_00125	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDFAHGHL_00126	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MDFAHGHL_00127	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDFAHGHL_00128	1.68e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDFAHGHL_00129	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDFAHGHL_00130	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MDFAHGHL_00131	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MDFAHGHL_00132	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDFAHGHL_00133	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDFAHGHL_00134	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDFAHGHL_00135	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDFAHGHL_00136	7.42e-99	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDFAHGHL_00137	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDFAHGHL_00138	7.25e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MDFAHGHL_00139	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDFAHGHL_00140	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDFAHGHL_00141	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MDFAHGHL_00142	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDFAHGHL_00143	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDFAHGHL_00144	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDFAHGHL_00145	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDFAHGHL_00146	1.41e-240	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MDFAHGHL_00147	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MDFAHGHL_00148	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDFAHGHL_00149	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MDFAHGHL_00150	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDFAHGHL_00151	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDFAHGHL_00152	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDFAHGHL_00153	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDFAHGHL_00154	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDFAHGHL_00155	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDFAHGHL_00156	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MDFAHGHL_00157	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDFAHGHL_00158	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDFAHGHL_00159	5.48e-12	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDFAHGHL_00160	7.7e-39	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDFAHGHL_00161	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDFAHGHL_00162	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDFAHGHL_00163	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDFAHGHL_00164	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDFAHGHL_00165	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDFAHGHL_00166	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDFAHGHL_00167	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MDFAHGHL_00168	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MDFAHGHL_00169	1.34e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDFAHGHL_00170	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDFAHGHL_00171	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MDFAHGHL_00172	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDFAHGHL_00173	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MDFAHGHL_00174	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDFAHGHL_00175	1.13e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDFAHGHL_00176	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDFAHGHL_00177	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MDFAHGHL_00178	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDFAHGHL_00179	7.28e-192	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDFAHGHL_00180	1.37e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDFAHGHL_00181	9.1e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDFAHGHL_00182	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDFAHGHL_00183	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MDFAHGHL_00184	7.48e-187	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MDFAHGHL_00185	6.11e-106	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MDFAHGHL_00186	3.22e-103	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MDFAHGHL_00187	1.98e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDFAHGHL_00188	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDFAHGHL_00189	6.81e-103	gerD	-	-	-	ko:K06294	-	ko00000	-
MDFAHGHL_00190	2.08e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MDFAHGHL_00191	1.29e-182	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MDFAHGHL_00192	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00198	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_00199	1.07e-188	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MDFAHGHL_00200	4.78e-38	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MDFAHGHL_00201	1.27e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDFAHGHL_00202	8.07e-233	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MDFAHGHL_00203	1.69e-257	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MDFAHGHL_00204	2.25e-287	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MDFAHGHL_00205	7.62e-223	ybaS	-	-	S	-	-	-	Na -dependent transporter
MDFAHGHL_00206	1.26e-148	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MDFAHGHL_00207	7.1e-230	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_00208	2.19e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_00209	1.21e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MDFAHGHL_00210	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MDFAHGHL_00211	3.46e-304	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00212	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MDFAHGHL_00213	5.62e-312	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MDFAHGHL_00214	3.7e-313	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_00215	1.2e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDFAHGHL_00216	1.82e-112	ybbJ	-	-	J	-	-	-	acetyltransferase
MDFAHGHL_00217	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MDFAHGHL_00223	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_00224	1.11e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MDFAHGHL_00225	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDFAHGHL_00226	2.33e-303	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00227	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDFAHGHL_00228	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDFAHGHL_00229	3.17e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MDFAHGHL_00230	1.36e-136	-	-	-	S	-	-	-	ABC-2 family transporter protein
MDFAHGHL_00231	3.07e-124	ybdN	-	-	-	-	-	-	-
MDFAHGHL_00232	2.23e-163	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MDFAHGHL_00233	1.47e-206	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MDFAHGHL_00234	7.37e-136	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MDFAHGHL_00235	1.41e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MDFAHGHL_00236	3.52e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_00237	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_00238	2.16e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDFAHGHL_00239	3.02e-256	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
MDFAHGHL_00240	5.23e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MDFAHGHL_00241	1.17e-218	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MDFAHGHL_00242	1.65e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MDFAHGHL_00243	1.61e-253	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MDFAHGHL_00244	2.34e-35	-	-	-	-	-	-	-	-
MDFAHGHL_00245	2.68e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
MDFAHGHL_00246	1.75e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MDFAHGHL_00247	1.52e-145	yqeB	-	-	-	-	-	-	-
MDFAHGHL_00248	7.84e-55	ybyB	-	-	-	-	-	-	-
MDFAHGHL_00249	0.0	ybeC	-	-	E	-	-	-	amino acid
MDFAHGHL_00250	1.04e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MDFAHGHL_00251	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MDFAHGHL_00252	4.08e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MDFAHGHL_00253	2.02e-267	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MDFAHGHL_00255	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MDFAHGHL_00256	2.44e-45	-	-	-	-	-	-	-	-
MDFAHGHL_00257	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDFAHGHL_00258	2.7e-258	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MDFAHGHL_00259	9.69e-273	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDFAHGHL_00260	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDFAHGHL_00261	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_00262	3.05e-194	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MDFAHGHL_00263	2.58e-56	ybfN	-	-	-	-	-	-	-
MDFAHGHL_00264	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MDFAHGHL_00265	6.43e-137	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_00266	6.61e-76	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_00267	2.15e-31	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_00268	5.02e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MDFAHGHL_00269	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDFAHGHL_00270	1.24e-231	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MDFAHGHL_00271	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MDFAHGHL_00272	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDFAHGHL_00273	6.52e-281	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_00274	7.91e-219	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MDFAHGHL_00275	5.89e-36	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MDFAHGHL_00276	1.64e-47	-	-	-	L	-	-	-	Transposase
MDFAHGHL_00277	4.47e-200	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDFAHGHL_00278	1.15e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MDFAHGHL_00279	7.8e-238	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDFAHGHL_00280	1.14e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MDFAHGHL_00281	1.32e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
MDFAHGHL_00282	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MDFAHGHL_00283	1.33e-104	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MDFAHGHL_00284	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MDFAHGHL_00285	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDFAHGHL_00286	8.93e-163	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDFAHGHL_00287	1.25e-156	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDFAHGHL_00288	8.52e-267	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MDFAHGHL_00289	7.61e-194	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MDFAHGHL_00291	2.19e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MDFAHGHL_00292	7.15e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MDFAHGHL_00293	9.81e-149	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDFAHGHL_00294	2.9e-253	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MDFAHGHL_00295	7.95e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
MDFAHGHL_00296	3.39e-228	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MDFAHGHL_00297	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_00298	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_00299	6.25e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MDFAHGHL_00300	9.98e-249	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MDFAHGHL_00301	1.1e-181	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_00302	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDFAHGHL_00303	2.99e-213	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDFAHGHL_00304	1.4e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDFAHGHL_00305	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDFAHGHL_00306	1.66e-190	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_00307	1.16e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MDFAHGHL_00308	3.63e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MDFAHGHL_00309	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MDFAHGHL_00310	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MDFAHGHL_00311	2.56e-47	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MDFAHGHL_00312	1.73e-96	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MDFAHGHL_00313	1.52e-176	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MDFAHGHL_00314	1.17e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
MDFAHGHL_00315	5.22e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MDFAHGHL_00316	7.71e-294	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MDFAHGHL_00317	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MDFAHGHL_00318	7e-211	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MDFAHGHL_00319	3.37e-272	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MDFAHGHL_00320	3.48e-178	ycgA	-	-	S	-	-	-	Membrane
MDFAHGHL_00321	1.64e-88	ycgA	-	-	S	-	-	-	Membrane
MDFAHGHL_00322	1.32e-107	ycgB	-	-	-	-	-	-	-
MDFAHGHL_00323	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MDFAHGHL_00324	1.62e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDFAHGHL_00325	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MDFAHGHL_00326	6.92e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_00327	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MDFAHGHL_00328	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MDFAHGHL_00329	5.64e-315	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_00330	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MDFAHGHL_00331	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDFAHGHL_00332	2.78e-82	ymzB	-	-	-	-	-	-	-
MDFAHGHL_00333	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MDFAHGHL_00334	3.03e-06	-	-	-	-	-	-	-	-
MDFAHGHL_00335	6.85e-164	ymaC	-	-	S	-	-	-	Replication protein
MDFAHGHL_00336	7.27e-106	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MDFAHGHL_00337	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MDFAHGHL_00338	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MDFAHGHL_00340	2.08e-77	ymaF	-	-	S	-	-	-	YmaF family
MDFAHGHL_00341	2.19e-220	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDFAHGHL_00342	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MDFAHGHL_00343	1.21e-58	-	-	-	-	-	-	-	-
MDFAHGHL_00344	9.42e-29	ymzA	-	-	-	-	-	-	-
MDFAHGHL_00345	1.61e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MDFAHGHL_00346	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDFAHGHL_00347	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDFAHGHL_00348	2.15e-139	ymaB	-	-	S	-	-	-	MutT family
MDFAHGHL_00349	2.64e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDFAHGHL_00350	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MDFAHGHL_00351	4e-173	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDFAHGHL_00352	3.71e-89	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDFAHGHL_00353	1.01e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MDFAHGHL_00354	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MDFAHGHL_00355	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MDFAHGHL_00356	1.43e-273	mrjp	-	-	G	-	-	-	Major royal jelly protein
MDFAHGHL_00357	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MDFAHGHL_00358	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MDFAHGHL_00359	6.1e-276	xylR	-	-	GK	-	-	-	ROK family
MDFAHGHL_00360	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MDFAHGHL_00361	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MDFAHGHL_00362	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MDFAHGHL_00367	2.21e-27	-	-	-	-	-	-	-	-
MDFAHGHL_00368	1.77e-152	yobV	-	-	K	-	-	-	WYL domain
MDFAHGHL_00369	1.58e-85	dinB	-	-	S	-	-	-	DinB family
MDFAHGHL_00370	5.08e-238	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MDFAHGHL_00372	6.73e-23	-	-	-	-	-	-	-	-
MDFAHGHL_00374	5.21e-49	-	-	-	-	-	-	-	-
MDFAHGHL_00375	2.36e-06	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDFAHGHL_00376	5.71e-190	yoaP	-	-	K	-	-	-	YoaP-like
MDFAHGHL_00377	2.92e-131	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_00378	6.77e-54	-	-	-	-	-	-	-	-
MDFAHGHL_00380	2.09e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MDFAHGHL_00381	4.15e-258	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_00382	1.65e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
MDFAHGHL_00383	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDFAHGHL_00384	7.75e-126	yvgO	-	-	-	-	-	-	-
MDFAHGHL_00386	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MDFAHGHL_00387	1.49e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MDFAHGHL_00388	2.21e-188	yndL	-	-	S	-	-	-	Replication protein
MDFAHGHL_00389	1.74e-11	-	-	-	-	-	-	-	-
MDFAHGHL_00390	6.29e-185	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MDFAHGHL_00391	1.85e-94	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MDFAHGHL_00393	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDFAHGHL_00394	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MDFAHGHL_00395	5.22e-145	yneB	-	-	L	-	-	-	resolvase
MDFAHGHL_00396	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MDFAHGHL_00397	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MDFAHGHL_00398	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MDFAHGHL_00399	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MDFAHGHL_00400	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MDFAHGHL_00401	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MDFAHGHL_00402	2.47e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MDFAHGHL_00403	1.31e-97	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MDFAHGHL_00404	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MDFAHGHL_00405	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MDFAHGHL_00406	8.04e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MDFAHGHL_00407	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MDFAHGHL_00408	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDFAHGHL_00409	3.46e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MDFAHGHL_00411	1.48e-45	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MDFAHGHL_00412	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MDFAHGHL_00413	4.68e-71	yneQ	-	-	-	-	-	-	-
MDFAHGHL_00414	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MDFAHGHL_00415	9.09e-121	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDFAHGHL_00416	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MDFAHGHL_00417	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDFAHGHL_00418	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDFAHGHL_00419	3.81e-20	-	-	-	-	-	-	-	-
MDFAHGHL_00420	1.82e-63	ynfC	-	-	-	-	-	-	-
MDFAHGHL_00421	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MDFAHGHL_00422	4.68e-233	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MDFAHGHL_00423	6.78e-248	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MDFAHGHL_00424	7.48e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MDFAHGHL_00425	1.18e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MDFAHGHL_00426	1.5e-193	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_00427	1.57e-234	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MDFAHGHL_00428	2.27e-288	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
MDFAHGHL_00429	1.85e-204	yndG	-	-	S	-	-	-	DoxX-like family
MDFAHGHL_00430	3.17e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MDFAHGHL_00431	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MDFAHGHL_00432	6.01e-94	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
MDFAHGHL_00433	3.31e-81	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDFAHGHL_00436	3.29e-276	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
MDFAHGHL_00437	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MDFAHGHL_00438	1.8e-70	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
MDFAHGHL_00439	3.58e-316	-	-	-	T	-	-	-	Histidine kinase
MDFAHGHL_00440	9.31e-165	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MDFAHGHL_00441	0.0	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MDFAHGHL_00442	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MDFAHGHL_00443	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00444	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00445	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00446	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00447	7.55e-285	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_00448	4.99e-179	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MDFAHGHL_00449	1.29e-156	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDFAHGHL_00450	8.91e-162	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDFAHGHL_00451	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MDFAHGHL_00452	1.12e-285	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDFAHGHL_00453	1.94e-247	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MDFAHGHL_00454	4.31e-166	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MDFAHGHL_00455	9.71e-274	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDFAHGHL_00456	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MDFAHGHL_00457	6.17e-191	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MDFAHGHL_00458	5.53e-96	yngA	-	-	S	-	-	-	membrane
MDFAHGHL_00459	3.73e-208	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDFAHGHL_00460	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_00461	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDFAHGHL_00462	4.99e-178	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MDFAHGHL_00463	4.23e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MDFAHGHL_00464	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MDFAHGHL_00465	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MDFAHGHL_00466	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDFAHGHL_00467	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MDFAHGHL_00468	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MDFAHGHL_00469	4.5e-28	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MDFAHGHL_00470	1.31e-19	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MDFAHGHL_00471	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
MDFAHGHL_00472	1.01e-300	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00473	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00474	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00475	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00476	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00477	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00478	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_00479	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MDFAHGHL_00480	2.01e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDFAHGHL_00481	3.69e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
MDFAHGHL_00482	2.7e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MDFAHGHL_00484	3.97e-125	-	-	-	L	-	-	-	Integrase
MDFAHGHL_00485	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MDFAHGHL_00486	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MDFAHGHL_00487	1.68e-256	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
MDFAHGHL_00488	3.29e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MDFAHGHL_00489	3.65e-17	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDFAHGHL_00490	3.85e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_00491	1.77e-239	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDFAHGHL_00492	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MDFAHGHL_00493	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MDFAHGHL_00494	7.8e-207	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_00495	2.07e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDFAHGHL_00496	7.2e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDFAHGHL_00497	3.37e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MDFAHGHL_00498	6.1e-101	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDFAHGHL_00499	1.45e-77	-	-	-	L	-	-	-	Transposase
MDFAHGHL_00500	1.44e-180	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_00501	3.47e-286	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDFAHGHL_00502	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_00503	1.45e-57	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDFAHGHL_00504	9.79e-182	yoxB	-	-	-	-	-	-	-
MDFAHGHL_00505	7.72e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MDFAHGHL_00506	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MDFAHGHL_00507	1.48e-246	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDFAHGHL_00508	8.34e-201	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDFAHGHL_00509	2.32e-269	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDFAHGHL_00510	8.56e-34	yoaF	-	-	-	-	-	-	-
MDFAHGHL_00512	8.07e-129	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_00513	5.71e-58	-	-	-	-	-	-	-	-
MDFAHGHL_00514	2.62e-100	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MDFAHGHL_00515	5.27e-146	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDFAHGHL_00516	8.94e-44	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MDFAHGHL_00517	3.67e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MDFAHGHL_00518	1.06e-172	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDFAHGHL_00519	1.16e-120	yobS	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_00520	8.07e-174	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDFAHGHL_00521	7.8e-119	yobW	-	-	-	-	-	-	-
MDFAHGHL_00522	7.69e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MDFAHGHL_00523	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDFAHGHL_00524	1.33e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MDFAHGHL_00525	1.23e-181	-	-	-	J	-	-	-	Protein required for attachment to host cells
MDFAHGHL_00526	1.6e-123	yocC	-	-	-	-	-	-	-
MDFAHGHL_00527	3.47e-243	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MDFAHGHL_00529	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MDFAHGHL_00530	6.72e-103	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDFAHGHL_00531	3.17e-246	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDFAHGHL_00532	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDFAHGHL_00534	2.13e-77	yocK	-	-	T	-	-	-	general stress protein
MDFAHGHL_00535	1.35e-13	yocL	-	-	-	-	-	-	-
MDFAHGHL_00536	3.51e-13	yocN	-	-	-	-	-	-	-
MDFAHGHL_00537	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDFAHGHL_00538	9.63e-60	yozN	-	-	-	-	-	-	-
MDFAHGHL_00539	6.36e-50	yocN	-	-	-	-	-	-	-
MDFAHGHL_00540	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
MDFAHGHL_00542	4.69e-43	yozC	-	-	-	-	-	-	-
MDFAHGHL_00543	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDFAHGHL_00544	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MDFAHGHL_00545	3.49e-214	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MDFAHGHL_00546	1.19e-297	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDFAHGHL_00547	1.52e-216	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MDFAHGHL_00548	1.15e-182	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MDFAHGHL_00549	7.41e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MDFAHGHL_00550	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MDFAHGHL_00551	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MDFAHGHL_00552	4.2e-209	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MDFAHGHL_00553	9.26e-145	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MDFAHGHL_00554	1.56e-295	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDFAHGHL_00555	3.76e-285	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MDFAHGHL_00556	5.48e-143	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDFAHGHL_00558	1.69e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MDFAHGHL_00559	8.69e-195	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDFAHGHL_00560	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MDFAHGHL_00561	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MDFAHGHL_00562	1.28e-31	-	-	-	-	-	-	-	-
MDFAHGHL_00563	2.96e-210	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MDFAHGHL_00564	1.4e-105	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MDFAHGHL_00566	2.59e-89	iolK	-	-	S	-	-	-	tautomerase
MDFAHGHL_00567	7.87e-92	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MDFAHGHL_00568	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
MDFAHGHL_00569	1.91e-138	yodC	-	-	C	-	-	-	nitroreductase
MDFAHGHL_00570	1.25e-142	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MDFAHGHL_00571	5.62e-224	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDFAHGHL_00572	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MDFAHGHL_00573	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDFAHGHL_00574	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MDFAHGHL_00575	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_00576	8.67e-170	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_00577	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MDFAHGHL_00578	2.6e-167	yodH	-	-	Q	-	-	-	Methyltransferase
MDFAHGHL_00579	1.68e-50	yodI	-	-	-	-	-	-	-
MDFAHGHL_00580	7.76e-193	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MDFAHGHL_00581	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MDFAHGHL_00583	1.11e-70	yodL	-	-	S	-	-	-	YodL-like
MDFAHGHL_00584	4.5e-135	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MDFAHGHL_00585	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
MDFAHGHL_00587	1.9e-161	yodN	-	-	-	-	-	-	-
MDFAHGHL_00588	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MDFAHGHL_00589	9.87e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MDFAHGHL_00590	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MDFAHGHL_00591	2.95e-205	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MDFAHGHL_00592	3.44e-301	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MDFAHGHL_00593	2.68e-159	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDFAHGHL_00594	4.47e-145	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDFAHGHL_00595	7.18e-314	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDFAHGHL_00597	7.24e-188	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MDFAHGHL_00598	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MDFAHGHL_00599	6.96e-64	cgeC	-	-	-	ko:K06321	-	ko00000	-
MDFAHGHL_00600	9.32e-92	cgeA	-	-	-	ko:K06319	-	ko00000	-
MDFAHGHL_00601	1.34e-232	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MDFAHGHL_00602	2.33e-284	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MDFAHGHL_00603	3.54e-95	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MDFAHGHL_00608	1.49e-273	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDFAHGHL_00609	5.52e-35	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDFAHGHL_00610	0.0	baeB	3.1.2.6	-	P	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Rhodanese Homology Domain
MDFAHGHL_00611	5.58e-291	-	1.8.5.4	-	S	ko:K17218	ko00920,map00920	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MDFAHGHL_00612	1.56e-124	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
MDFAHGHL_00613	2.69e-254	-	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_00614	7.02e-144	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDFAHGHL_00616	9.7e-133	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MDFAHGHL_00617	1.63e-165	-	-	-	S	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved WHH
MDFAHGHL_00618	3.09e-61	-	-	-	V	-	-	-	HNH endonuclease
MDFAHGHL_00619	9.03e-48	-	-	-	V	-	-	-	HNH endonuclease
MDFAHGHL_00620	2.86e-75	-	-	-	V	-	-	-	HNH endonuclease
MDFAHGHL_00621	7.74e-121	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MDFAHGHL_00622	8.41e-108	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MDFAHGHL_00623	0.0	yokA	-	-	L	-	-	-	Recombinase
MDFAHGHL_00624	1.37e-134	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MDFAHGHL_00625	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MDFAHGHL_00626	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDFAHGHL_00627	8.22e-90	ypoP	-	-	K	-	-	-	transcriptional
MDFAHGHL_00628	4.79e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00629	1.05e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDFAHGHL_00630	8.84e-138	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MDFAHGHL_00631	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MDFAHGHL_00632	4.46e-250	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MDFAHGHL_00633	3.27e-230	yplP	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_00634	3.69e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MDFAHGHL_00635	1.55e-72	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
MDFAHGHL_00636	6.97e-150	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDFAHGHL_00637	3.66e-118	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDFAHGHL_00638	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDFAHGHL_00639	4.24e-67	ypjP	-	-	S	-	-	-	YpjP-like protein
MDFAHGHL_00640	4.6e-68	ypjP	-	-	S	-	-	-	YpjP-like protein
MDFAHGHL_00641	6.04e-173	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MDFAHGHL_00642	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MDFAHGHL_00643	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MDFAHGHL_00644	4.02e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MDFAHGHL_00645	3.26e-128	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MDFAHGHL_00646	1.13e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MDFAHGHL_00647	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDFAHGHL_00648	5.21e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MDFAHGHL_00649	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MDFAHGHL_00650	1.27e-17	degR	-	-	-	-	-	-	-
MDFAHGHL_00651	1.13e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MDFAHGHL_00652	3.82e-39	ypeQ	-	-	S	-	-	-	Zinc-finger
MDFAHGHL_00653	2.06e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MDFAHGHL_00654	2.79e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MDFAHGHL_00655	7.37e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MDFAHGHL_00657	9.55e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
MDFAHGHL_00658	2.44e-10	-	-	-	-	-	-	-	-
MDFAHGHL_00659	7.03e-53	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MDFAHGHL_00660	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MDFAHGHL_00661	1.26e-117	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MDFAHGHL_00662	8.31e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MDFAHGHL_00663	1.56e-79	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_00664	1.69e-50	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_00665	3.81e-67	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
MDFAHGHL_00666	2.17e-12	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MDFAHGHL_00667	6.17e-124	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDFAHGHL_00668	1.32e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
MDFAHGHL_00669	1.78e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MDFAHGHL_00670	1.77e-298	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MDFAHGHL_00671	2.85e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDFAHGHL_00672	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MDFAHGHL_00673	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MDFAHGHL_00675	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
MDFAHGHL_00676	6.65e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MDFAHGHL_00677	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDFAHGHL_00678	3.27e-129	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MDFAHGHL_00679	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MDFAHGHL_00681	1.99e-302	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MDFAHGHL_00682	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MDFAHGHL_00683	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MDFAHGHL_00684	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDFAHGHL_00685	2.85e-82	yppG	-	-	S	-	-	-	YppG-like protein
MDFAHGHL_00689	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
MDFAHGHL_00690	2e-239	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MDFAHGHL_00691	2.54e-145	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDFAHGHL_00692	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDFAHGHL_00693	5.18e-119	ypoC	-	-	-	-	-	-	-
MDFAHGHL_00694	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDFAHGHL_00695	2.81e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MDFAHGHL_00696	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MDFAHGHL_00697	4.19e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MDFAHGHL_00698	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00699	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MDFAHGHL_00700	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MDFAHGHL_00701	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MDFAHGHL_00702	9.87e-203	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MDFAHGHL_00703	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MDFAHGHL_00704	4.61e-71	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDFAHGHL_00705	5.45e-19	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDFAHGHL_00706	2.46e-63	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDFAHGHL_00707	5.92e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDFAHGHL_00708	7.63e-271	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MDFAHGHL_00709	1.56e-170	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MDFAHGHL_00710	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MDFAHGHL_00711	9.78e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDFAHGHL_00712	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MDFAHGHL_00713	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_00714	4.94e-290	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MDFAHGHL_00715	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
MDFAHGHL_00716	2.63e-136	ypjA	-	-	S	-	-	-	membrane
MDFAHGHL_00717	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MDFAHGHL_00718	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MDFAHGHL_00719	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MDFAHGHL_00720	5.77e-102	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MDFAHGHL_00721	2.6e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MDFAHGHL_00722	7.49e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDFAHGHL_00723	1.43e-296	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDFAHGHL_00724	5.29e-262	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MDFAHGHL_00725	9.08e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDFAHGHL_00726	1.14e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDFAHGHL_00727	7.05e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDFAHGHL_00728	3.69e-150	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MDFAHGHL_00729	1.17e-167	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MDFAHGHL_00730	6.78e-211	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDFAHGHL_00731	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDFAHGHL_00732	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MDFAHGHL_00733	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDFAHGHL_00734	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDFAHGHL_00735	1.58e-178	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MDFAHGHL_00736	1.47e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MDFAHGHL_00737	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDFAHGHL_00738	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDFAHGHL_00739	9.74e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MDFAHGHL_00740	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MDFAHGHL_00741	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MDFAHGHL_00742	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDFAHGHL_00743	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MDFAHGHL_00744	6.87e-173	yphF	-	-	-	-	-	-	-
MDFAHGHL_00745	2.29e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MDFAHGHL_00746	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MDFAHGHL_00747	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MDFAHGHL_00748	3.22e-90	yphA	-	-	-	-	-	-	-
MDFAHGHL_00749	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
MDFAHGHL_00750	5.92e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDFAHGHL_00751	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MDFAHGHL_00752	8.24e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MDFAHGHL_00753	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MDFAHGHL_00754	7.01e-74	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MDFAHGHL_00755	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MDFAHGHL_00756	9.24e-214	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MDFAHGHL_00757	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MDFAHGHL_00758	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MDFAHGHL_00759	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDFAHGHL_00760	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDFAHGHL_00761	1.15e-189	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MDFAHGHL_00762	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MDFAHGHL_00763	7.16e-133	ypbE	-	-	M	-	-	-	Lysin motif
MDFAHGHL_00764	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MDFAHGHL_00765	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDFAHGHL_00766	4.63e-166	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MDFAHGHL_00767	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MDFAHGHL_00768	2.53e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDFAHGHL_00769	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDFAHGHL_00770	1.44e-256	rsiX	-	-	-	-	-	-	-
MDFAHGHL_00771	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_00772	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_00773	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_00774	3.6e-251	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MDFAHGHL_00775	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MDFAHGHL_00776	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MDFAHGHL_00777	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDFAHGHL_00778	8.99e-116	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MDFAHGHL_00779	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MDFAHGHL_00780	9.35e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDFAHGHL_00781	1.51e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MDFAHGHL_00782	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDFAHGHL_00783	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDFAHGHL_00785	1.99e-121	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MDFAHGHL_00786	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDFAHGHL_00787	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDFAHGHL_00788	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDFAHGHL_00789	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MDFAHGHL_00790	2.76e-270	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDFAHGHL_00791	4.92e-71	ypuD	-	-	-	-	-	-	-
MDFAHGHL_00792	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDFAHGHL_00793	7.89e-105	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
MDFAHGHL_00794	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDFAHGHL_00795	6.31e-199	ypuA	-	-	S	-	-	-	Secreted protein
MDFAHGHL_00796	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDFAHGHL_00797	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MDFAHGHL_00798	1.31e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MDFAHGHL_00799	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MDFAHGHL_00800	8.19e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MDFAHGHL_00801	9.92e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MDFAHGHL_00802	1.89e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MDFAHGHL_00803	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MDFAHGHL_00804	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_00805	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MDFAHGHL_00806	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MDFAHGHL_00807	1.43e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDFAHGHL_00808	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MDFAHGHL_00809	1.22e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDFAHGHL_00810	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MDFAHGHL_00811	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MDFAHGHL_00812	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MDFAHGHL_00813	1.96e-30	-	-	-	-	-	-	-	-
MDFAHGHL_00814	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MDFAHGHL_00815	5.23e-268	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MDFAHGHL_00816	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MDFAHGHL_00817	6.19e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MDFAHGHL_00818	6.9e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_00819	1.75e-21	yqxK	-	-	L	-	-	-	DNA helicase
MDFAHGHL_00820	1.13e-223	yqxK	-	-	L	-	-	-	DNA helicase
MDFAHGHL_00821	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MDFAHGHL_00822	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MDFAHGHL_00823	2.27e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MDFAHGHL_00824	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MDFAHGHL_00825	3e-228	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MDFAHGHL_00826	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MDFAHGHL_00827	5.4e-80	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MDFAHGHL_00828	9.08e-227	yqkA	-	-	K	-	-	-	GrpB protein
MDFAHGHL_00829	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MDFAHGHL_00830	1.9e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MDFAHGHL_00831	1.74e-106	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDFAHGHL_00832	2.11e-152	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDFAHGHL_00833	4.38e-74	-	-	-	S	-	-	-	YolD-like protein
MDFAHGHL_00835	6.44e-243	yueF	-	-	S	-	-	-	transporter activity
MDFAHGHL_00837	2.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_00838	6.33e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDFAHGHL_00839	1.07e-250	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MDFAHGHL_00840	1.24e-60	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MDFAHGHL_00841	8.69e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_00842	9.69e-224	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDFAHGHL_00843	8.27e-187	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDFAHGHL_00844	4.14e-176	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MDFAHGHL_00845	9.58e-307	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MDFAHGHL_00846	1.4e-281	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDFAHGHL_00847	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDFAHGHL_00848	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDFAHGHL_00849	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00850	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00851	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00852	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00853	6.72e-289	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00854	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00855	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00856	1.53e-295	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00857	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00858	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00859	6.85e-67	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00860	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_00861	2.78e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MDFAHGHL_00862	1.93e-314	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDFAHGHL_00865	3.97e-63	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_00866	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_00867	5.26e-123	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDFAHGHL_00868	1.59e-211	-	-	-	K	-	-	-	LysR substrate binding domain
MDFAHGHL_00869	6.03e-43	-	-	-	S	-	-	-	GlpM protein
MDFAHGHL_00870	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MDFAHGHL_00871	2.72e-190	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDFAHGHL_00872	9.66e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDFAHGHL_00873	8.09e-158	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDFAHGHL_00874	1.39e-179	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDFAHGHL_00875	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDFAHGHL_00876	1.16e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDFAHGHL_00877	1.3e-34	yqzJ	-	-	-	-	-	-	-
MDFAHGHL_00878	4.13e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDFAHGHL_00879	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MDFAHGHL_00880	3.07e-41	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDFAHGHL_00881	5.54e-286	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDFAHGHL_00882	2.69e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MDFAHGHL_00884	5.47e-125	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00885	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MDFAHGHL_00886	2.58e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDFAHGHL_00887	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDFAHGHL_00888	5.83e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDFAHGHL_00889	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MDFAHGHL_00890	1.48e-219	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDFAHGHL_00891	3.75e-286	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDFAHGHL_00892	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDFAHGHL_00893	2.92e-115	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDFAHGHL_00894	8.82e-72	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDFAHGHL_00895	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDFAHGHL_00896	1.2e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MDFAHGHL_00897	1.58e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDFAHGHL_00898	6.8e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MDFAHGHL_00899	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MDFAHGHL_00900	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MDFAHGHL_00901	2.82e-205	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MDFAHGHL_00902	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MDFAHGHL_00903	1.07e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDFAHGHL_00904	2.25e-263	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MDFAHGHL_00905	1.24e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MDFAHGHL_00906	1.4e-202	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDFAHGHL_00907	3.85e-49	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDFAHGHL_00908	1.9e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDFAHGHL_00909	2.51e-127	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MDFAHGHL_00911	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MDFAHGHL_00912	6.93e-147	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
MDFAHGHL_00914	1.37e-273	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MDFAHGHL_00917	0.000208	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDFAHGHL_00918	3.59e-250	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDFAHGHL_00919	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MDFAHGHL_00920	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MDFAHGHL_00921	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MDFAHGHL_00922	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MDFAHGHL_00923	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MDFAHGHL_00924	9.48e-126	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDFAHGHL_00925	8.18e-314	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDFAHGHL_00926	8.13e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDFAHGHL_00927	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDFAHGHL_00928	1.35e-314	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDFAHGHL_00929	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDFAHGHL_00930	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDFAHGHL_00931	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_00932	2.91e-234	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MDFAHGHL_00933	1.27e-67	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MDFAHGHL_00934	1.64e-57	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDFAHGHL_00935	1.82e-13	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDFAHGHL_00936	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MDFAHGHL_00937	7.03e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MDFAHGHL_00938	1.05e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MDFAHGHL_00939	3.02e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MDFAHGHL_00940	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MDFAHGHL_00941	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MDFAHGHL_00942	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MDFAHGHL_00943	3.12e-221	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MDFAHGHL_00944	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MDFAHGHL_00945	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDFAHGHL_00946	6.04e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MDFAHGHL_00947	3.99e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MDFAHGHL_00948	1.04e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MDFAHGHL_00949	7.65e-83	yqhP	-	-	-	-	-	-	-
MDFAHGHL_00950	7e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MDFAHGHL_00951	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MDFAHGHL_00952	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MDFAHGHL_00953	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MDFAHGHL_00954	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDFAHGHL_00955	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDFAHGHL_00956	1.16e-264	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MDFAHGHL_00957	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDFAHGHL_00958	3.57e-194	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MDFAHGHL_00959	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MDFAHGHL_00960	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MDFAHGHL_00961	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MDFAHGHL_00962	3.27e-103	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MDFAHGHL_00963	1.98e-157	yqxM	-	-	-	ko:K19433	-	ko00000	-
MDFAHGHL_00964	1.69e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MDFAHGHL_00965	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
MDFAHGHL_00966	4.9e-83	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MDFAHGHL_00967	1.58e-88	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MDFAHGHL_00968	6.31e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MDFAHGHL_00969	3.93e-94	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
MDFAHGHL_00970	4.46e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MDFAHGHL_00971	2.62e-239	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MDFAHGHL_00972	3.84e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MDFAHGHL_00973	4.53e-239	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MDFAHGHL_00974	9.23e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDFAHGHL_00975	2.49e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDFAHGHL_00977	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MDFAHGHL_00978	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MDFAHGHL_00979	3.45e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MDFAHGHL_00980	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MDFAHGHL_00981	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
MDFAHGHL_00982	4.35e-23	yqgU	-	-	-	-	-	-	-
MDFAHGHL_00983	1.48e-201	yqgU	-	-	-	-	-	-	-
MDFAHGHL_00984	1.06e-285	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MDFAHGHL_00985	4.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MDFAHGHL_00986	9.1e-39	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MDFAHGHL_00987	2.96e-275	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MDFAHGHL_00988	5.38e-11	yqgO	-	-	-	-	-	-	-
MDFAHGHL_00989	8.98e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDFAHGHL_00990	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDFAHGHL_00991	3.42e-68	yqzD	-	-	-	-	-	-	-
MDFAHGHL_00992	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDFAHGHL_00993	2.32e-188	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDFAHGHL_00994	1.18e-185	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDFAHGHL_00995	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MDFAHGHL_00996	6.1e-204	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDFAHGHL_00997	9.5e-208	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDFAHGHL_00998	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MDFAHGHL_00999	2.37e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MDFAHGHL_01000	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MDFAHGHL_01001	4.77e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MDFAHGHL_01002	2.18e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MDFAHGHL_01003	1.84e-64	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MDFAHGHL_01004	1.97e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDFAHGHL_01005	9.58e-80	yqfX	-	-	S	-	-	-	membrane
MDFAHGHL_01006	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MDFAHGHL_01007	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MDFAHGHL_01008	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_01009	1.01e-47	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MDFAHGHL_01010	4.23e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDFAHGHL_01011	1.39e-313	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDFAHGHL_01012	2.24e-82	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MDFAHGHL_01013	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDFAHGHL_01014	4.58e-42	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
MDFAHGHL_01015	6.25e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDFAHGHL_01016	2.97e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MDFAHGHL_01017	1.95e-82	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MDFAHGHL_01018	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDFAHGHL_01019	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDFAHGHL_01020	3.33e-113	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MDFAHGHL_01021	2.38e-149	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDFAHGHL_01022	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
MDFAHGHL_01023	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MDFAHGHL_01024	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MDFAHGHL_01025	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MDFAHGHL_01026	6e-24	-	-	-	S	-	-	-	YqzL-like protein
MDFAHGHL_01027	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDFAHGHL_01028	1.58e-91	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MDFAHGHL_01029	6.41e-84	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MDFAHGHL_01030	7.14e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDFAHGHL_01031	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MDFAHGHL_01032	8.67e-67	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MDFAHGHL_01033	8.86e-117	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MDFAHGHL_01034	3.72e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MDFAHGHL_01035	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MDFAHGHL_01036	7.93e-89	yqfB	-	-	-	-	-	-	-
MDFAHGHL_01037	4.48e-189	yqfA	-	-	S	-	-	-	UPF0365 protein
MDFAHGHL_01038	7.39e-293	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MDFAHGHL_01039	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MDFAHGHL_01040	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MDFAHGHL_01041	8.3e-203	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MDFAHGHL_01042	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MDFAHGHL_01043	1.75e-181	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDFAHGHL_01044	6.58e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MDFAHGHL_01045	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDFAHGHL_01046	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MDFAHGHL_01047	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDFAHGHL_01048	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDFAHGHL_01049	3.95e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MDFAHGHL_01050	1.39e-194	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDFAHGHL_01051	1.2e-193	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDFAHGHL_01052	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MDFAHGHL_01053	2.6e-279	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MDFAHGHL_01054	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MDFAHGHL_01055	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MDFAHGHL_01056	6.36e-233	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MDFAHGHL_01057	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MDFAHGHL_01058	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MDFAHGHL_01059	1.39e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MDFAHGHL_01060	9.79e-192	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDFAHGHL_01061	2.52e-117	yqeM	-	-	Q	-	-	-	Methyltransferase
MDFAHGHL_01062	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDFAHGHL_01063	5.62e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MDFAHGHL_01064	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDFAHGHL_01065	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MDFAHGHL_01066	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDFAHGHL_01067	4.59e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MDFAHGHL_01068	4.96e-114	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MDFAHGHL_01070	1.85e-180	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDFAHGHL_01071	5.69e-181	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MDFAHGHL_01072	2.92e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_01073	3.43e-12	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDFAHGHL_01074	1.4e-280	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MDFAHGHL_01075	6.78e-160	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_01076	6.73e-207	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MDFAHGHL_01077	4.01e-122	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MDFAHGHL_01078	1.48e-190	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MDFAHGHL_01079	6.4e-129	yqaC	-	-	F	-	-	-	adenylate kinase activity
MDFAHGHL_01080	2.14e-71	-	-	-	K	-	-	-	acetyltransferase
MDFAHGHL_01081	1.42e-122	-	-	-	S	-	-	-	DinB family
MDFAHGHL_01083	1.76e-191	supH	-	-	S	-	-	-	hydrolase
MDFAHGHL_01084	3.03e-189	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDFAHGHL_01085	1.23e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDFAHGHL_01086	5.3e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDFAHGHL_01087	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_01088	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MDFAHGHL_01089	1.95e-107	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MDFAHGHL_01090	1.32e-107	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MDFAHGHL_01091	4.62e-107	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDFAHGHL_01092	7.89e-213	yybE	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01093	9.68e-273	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_01094	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MDFAHGHL_01095	3.36e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MDFAHGHL_01096	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
MDFAHGHL_01097	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MDFAHGHL_01098	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MDFAHGHL_01099	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MDFAHGHL_01100	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MDFAHGHL_01101	4.76e-106	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDFAHGHL_01102	1.92e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
MDFAHGHL_01103	7.93e-270	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDFAHGHL_01104	2.09e-69	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MDFAHGHL_01105	3.46e-122	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MDFAHGHL_01106	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDFAHGHL_01107	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MDFAHGHL_01108	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MDFAHGHL_01109	3.56e-124	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MDFAHGHL_01110	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MDFAHGHL_01111	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDFAHGHL_01112	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MDFAHGHL_01113	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MDFAHGHL_01114	1.81e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MDFAHGHL_01115	2.32e-153	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MDFAHGHL_01116	2.82e-259	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDFAHGHL_01117	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MDFAHGHL_01118	1.11e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDFAHGHL_01119	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MDFAHGHL_01120	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDFAHGHL_01121	2.82e-238	yrrI	-	-	S	-	-	-	AI-2E family transporter
MDFAHGHL_01122	1.14e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDFAHGHL_01123	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDFAHGHL_01124	1.38e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDFAHGHL_01125	7.94e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDFAHGHL_01126	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MDFAHGHL_01127	8.4e-42	yrzR	-	-	-	-	-	-	-
MDFAHGHL_01128	1.76e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01129	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDFAHGHL_01130	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDFAHGHL_01131	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDFAHGHL_01132	2.1e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDFAHGHL_01133	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_01134	9.19e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MDFAHGHL_01135	1.18e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MDFAHGHL_01136	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDFAHGHL_01137	3.58e-194	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDFAHGHL_01138	3.71e-55	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDFAHGHL_01141	4.66e-193	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MDFAHGHL_01142	3.48e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDFAHGHL_01143	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDFAHGHL_01144	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDFAHGHL_01145	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MDFAHGHL_01146	7.78e-63	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MDFAHGHL_01147	2.97e-110	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MDFAHGHL_01148	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MDFAHGHL_01149	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MDFAHGHL_01150	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_01151	2.64e-141	yrbG	-	-	S	-	-	-	membrane
MDFAHGHL_01152	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MDFAHGHL_01153	1.78e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MDFAHGHL_01154	2.49e-264	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDFAHGHL_01155	4.96e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MDFAHGHL_01156	1.39e-28	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MDFAHGHL_01157	6.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDFAHGHL_01158	1.8e-120	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDFAHGHL_01159	1.47e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MDFAHGHL_01161	8.92e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDFAHGHL_01162	1.59e-257	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MDFAHGHL_01163	1.04e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDFAHGHL_01164	5.7e-200	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MDFAHGHL_01165	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MDFAHGHL_01166	5.53e-13	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDFAHGHL_01167	8.4e-241	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDFAHGHL_01168	1.23e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MDFAHGHL_01169	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MDFAHGHL_01170	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MDFAHGHL_01171	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDFAHGHL_01172	3.64e-140	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MDFAHGHL_01173	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MDFAHGHL_01174	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MDFAHGHL_01175	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MDFAHGHL_01176	3.59e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MDFAHGHL_01177	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MDFAHGHL_01178	4.17e-22	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MDFAHGHL_01179	4.1e-144	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MDFAHGHL_01180	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MDFAHGHL_01181	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MDFAHGHL_01182	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MDFAHGHL_01183	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MDFAHGHL_01184	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MDFAHGHL_01185	8.25e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MDFAHGHL_01186	3.11e-209	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MDFAHGHL_01187	5.18e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MDFAHGHL_01188	4.6e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MDFAHGHL_01189	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDFAHGHL_01190	1.53e-35	-	-	-	-	-	-	-	-
MDFAHGHL_01191	7.7e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MDFAHGHL_01192	1.58e-310	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MDFAHGHL_01193	5.4e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MDFAHGHL_01194	1.2e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MDFAHGHL_01195	4.82e-100	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MDFAHGHL_01196	1.14e-57	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MDFAHGHL_01197	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MDFAHGHL_01198	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MDFAHGHL_01199	2.72e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MDFAHGHL_01200	8.26e-116	ysxD	-	-	-	-	-	-	-
MDFAHGHL_01201	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MDFAHGHL_01202	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MDFAHGHL_01203	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MDFAHGHL_01204	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDFAHGHL_01205	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDFAHGHL_01206	1.11e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MDFAHGHL_01207	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDFAHGHL_01208	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDFAHGHL_01209	3.68e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDFAHGHL_01210	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDFAHGHL_01211	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDFAHGHL_01212	7.17e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MDFAHGHL_01213	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MDFAHGHL_01217	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MDFAHGHL_01218	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDFAHGHL_01219	1.44e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDFAHGHL_01220	7.73e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MDFAHGHL_01221	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDFAHGHL_01222	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_01223	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_01224	2.67e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MDFAHGHL_01225	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MDFAHGHL_01226	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MDFAHGHL_01227	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MDFAHGHL_01228	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MDFAHGHL_01229	8.64e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDFAHGHL_01230	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDFAHGHL_01231	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDFAHGHL_01232	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MDFAHGHL_01233	5.22e-229	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MDFAHGHL_01234	8.64e-178	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MDFAHGHL_01235	1.43e-177	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MDFAHGHL_01236	1.23e-57	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_01237	1.9e-46	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_01238	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDFAHGHL_01239	4.68e-161	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MDFAHGHL_01240	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MDFAHGHL_01241	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDFAHGHL_01242	3.21e-250	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MDFAHGHL_01243	3.45e-116	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MDFAHGHL_01244	7.05e-108	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MDFAHGHL_01245	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MDFAHGHL_01246	1.08e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDFAHGHL_01247	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDFAHGHL_01248	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDFAHGHL_01249	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDFAHGHL_01250	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MDFAHGHL_01251	8.77e-262	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MDFAHGHL_01252	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
MDFAHGHL_01253	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MDFAHGHL_01254	1.11e-213	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MDFAHGHL_01255	6.2e-186	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MDFAHGHL_01256	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MDFAHGHL_01257	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MDFAHGHL_01258	4.38e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MDFAHGHL_01259	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MDFAHGHL_01260	5.75e-286	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MDFAHGHL_01261	1.85e-182	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MDFAHGHL_01262	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MDFAHGHL_01263	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MDFAHGHL_01264	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MDFAHGHL_01265	1.71e-241	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MDFAHGHL_01266	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MDFAHGHL_01267	9.71e-90	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MDFAHGHL_01268	4.65e-57	ysdA	-	-	S	-	-	-	Membrane
MDFAHGHL_01269	2.3e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDFAHGHL_01270	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MDFAHGHL_01271	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDFAHGHL_01272	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDFAHGHL_01273	1.12e-68	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
MDFAHGHL_01274	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MDFAHGHL_01275	1.46e-208	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01276	1.72e-181	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01277	7.21e-194	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MDFAHGHL_01278	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDFAHGHL_01279	1.99e-197	ytxC	-	-	S	-	-	-	YtxC-like family
MDFAHGHL_01280	3.36e-57	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_01281	3.97e-56	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_01282	1.42e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MDFAHGHL_01283	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MDFAHGHL_01284	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDFAHGHL_01285	4.31e-56	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MDFAHGHL_01286	2.42e-13	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MDFAHGHL_01287	2.19e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDFAHGHL_01288	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01289	1.69e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MDFAHGHL_01290	5.53e-206	ytbE	-	-	S	-	-	-	reductase
MDFAHGHL_01291	4.17e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDFAHGHL_01292	2e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MDFAHGHL_01293	1.99e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDFAHGHL_01294	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDFAHGHL_01295	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MDFAHGHL_01296	1.68e-166	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_01297	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MDFAHGHL_01298	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MDFAHGHL_01299	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDFAHGHL_01300	1.32e-69	-	-	-	-	-	-	-	-
MDFAHGHL_01301	5.5e-83	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MDFAHGHL_01302	5.65e-96	ytwI	-	-	S	-	-	-	membrane
MDFAHGHL_01303	9.96e-248	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MDFAHGHL_01304	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MDFAHGHL_01305	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MDFAHGHL_01306	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDFAHGHL_01307	1.15e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MDFAHGHL_01308	3.59e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDFAHGHL_01309	4.93e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MDFAHGHL_01310	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDFAHGHL_01311	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MDFAHGHL_01312	2.64e-114	ytrI	-	-	-	-	-	-	-
MDFAHGHL_01313	7.04e-32	-	-	-	-	-	-	-	-
MDFAHGHL_01314	3.38e-186	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MDFAHGHL_01315	3.38e-10	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MDFAHGHL_01316	1.06e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MDFAHGHL_01317	6.77e-305	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MDFAHGHL_01318	8.4e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MDFAHGHL_01319	5.9e-184	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_01321	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MDFAHGHL_01322	2.74e-291	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDFAHGHL_01323	4.03e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MDFAHGHL_01324	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDFAHGHL_01325	3.22e-208	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MDFAHGHL_01326	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDFAHGHL_01327	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MDFAHGHL_01328	1.79e-104	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MDFAHGHL_01329	1.5e-26	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MDFAHGHL_01330	3.93e-114	yteJ	-	-	S	-	-	-	RDD family
MDFAHGHL_01331	6.39e-235	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MDFAHGHL_01332	2.32e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDFAHGHL_01333	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MDFAHGHL_01334	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDFAHGHL_01335	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MDFAHGHL_01336	1.47e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDFAHGHL_01337	7.85e-205	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDFAHGHL_01338	2.88e-27	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MDFAHGHL_01339	2.62e-06	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDFAHGHL_01340	6.31e-289	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDFAHGHL_01341	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDFAHGHL_01342	6.38e-193	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MDFAHGHL_01343	4e-140	yttP	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01344	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MDFAHGHL_01345	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MDFAHGHL_01346	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDFAHGHL_01347	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDFAHGHL_01348	1.18e-128	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MDFAHGHL_01349	2.25e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MDFAHGHL_01351	7.42e-113	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MDFAHGHL_01353	2.49e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MDFAHGHL_01355	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDFAHGHL_01356	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01357	5.77e-160	ygaZ	-	-	E	-	-	-	AzlC protein
MDFAHGHL_01358	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MDFAHGHL_01359	6.98e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDFAHGHL_01360	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDFAHGHL_01361	4.72e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MDFAHGHL_01362	5.92e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MDFAHGHL_01363	2.2e-176	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MDFAHGHL_01364	4.27e-155	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MDFAHGHL_01365	8.63e-185	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MDFAHGHL_01366	4.86e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MDFAHGHL_01367	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MDFAHGHL_01368	1.45e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MDFAHGHL_01369	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MDFAHGHL_01370	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDFAHGHL_01371	1.07e-187	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDFAHGHL_01372	2.16e-83	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDFAHGHL_01373	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDFAHGHL_01374	9.89e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDFAHGHL_01375	1.71e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MDFAHGHL_01376	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
MDFAHGHL_01377	1.66e-101	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MDFAHGHL_01378	4.33e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MDFAHGHL_01379	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
MDFAHGHL_01380	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MDFAHGHL_01381	1.36e-211	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDFAHGHL_01382	1.3e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDFAHGHL_01383	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
MDFAHGHL_01384	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
MDFAHGHL_01385	1.18e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDFAHGHL_01386	1.72e-215	ytlQ	-	-	-	-	-	-	-
MDFAHGHL_01387	3.82e-133	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MDFAHGHL_01388	2.77e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDFAHGHL_01389	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MDFAHGHL_01390	1.22e-289	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDFAHGHL_01391	1.29e-278	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MDFAHGHL_01392	7.72e-165	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDFAHGHL_01393	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MDFAHGHL_01394	8.68e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDFAHGHL_01395	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_01396	9.17e-300	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MDFAHGHL_01397	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MDFAHGHL_01398	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MDFAHGHL_01399	3.18e-238	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_01400	2.28e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDFAHGHL_01401	1.95e-218	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDFAHGHL_01402	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MDFAHGHL_01403	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MDFAHGHL_01404	2.06e-112	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_01405	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MDFAHGHL_01406	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MDFAHGHL_01407	6.16e-59	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MDFAHGHL_01408	3.72e-178	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MDFAHGHL_01409	2.46e-271	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MDFAHGHL_01410	1.88e-163	ywaF	-	-	S	-	-	-	Integral membrane protein
MDFAHGHL_01411	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MDFAHGHL_01412	9.35e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_01413	3.03e-222	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MDFAHGHL_01414	4.49e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_01415	1.36e-287	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MDFAHGHL_01416	4.27e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_01417	3.66e-209	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MDFAHGHL_01418	1.19e-231	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDFAHGHL_01419	3.86e-216	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDFAHGHL_01420	5.11e-208	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_01421	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MDFAHGHL_01423	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MDFAHGHL_01424	1.65e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MDFAHGHL_01425	3.1e-137	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MDFAHGHL_01427	1.28e-185	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
MDFAHGHL_01428	7.04e-272	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MDFAHGHL_01429	5.71e-193	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MDFAHGHL_01430	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MDFAHGHL_01431	3.13e-291	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_01432	2.81e-13	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_01433	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDFAHGHL_01434	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDFAHGHL_01435	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MDFAHGHL_01436	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MDFAHGHL_01437	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MDFAHGHL_01438	4.53e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MDFAHGHL_01439	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDFAHGHL_01440	7.52e-174	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDFAHGHL_01441	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MDFAHGHL_01442	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MDFAHGHL_01443	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MDFAHGHL_01445	1.21e-98	ytkA	-	-	S	-	-	-	YtkA-like
MDFAHGHL_01446	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDFAHGHL_01447	6.93e-53	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MDFAHGHL_01448	2.67e-136	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MDFAHGHL_01449	1.23e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MDFAHGHL_01450	3.68e-312	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MDFAHGHL_01451	6.38e-236	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MDFAHGHL_01453	4.98e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MDFAHGHL_01454	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDFAHGHL_01455	7.52e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDFAHGHL_01456	8.79e-200	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MDFAHGHL_01457	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MDFAHGHL_01458	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MDFAHGHL_01459	1.28e-170	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MDFAHGHL_01460	9.03e-103	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MDFAHGHL_01482	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_01484	1.46e-126	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MDFAHGHL_01485	1.08e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MDFAHGHL_01486	1.96e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MDFAHGHL_01487	1.08e-106	yuaE	-	-	S	-	-	-	DinB superfamily
MDFAHGHL_01488	2.88e-116	-	-	-	S	-	-	-	MOSC domain
MDFAHGHL_01489	1.74e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MDFAHGHL_01490	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDFAHGHL_01491	3.51e-125	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MDFAHGHL_01492	2.03e-122	yuaB	-	-	-	-	-	-	-
MDFAHGHL_01493	4.31e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MDFAHGHL_01494	4.65e-194	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDFAHGHL_01495	1.46e-282	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MDFAHGHL_01496	6.7e-160	-	-	-	G	-	-	-	Cupin
MDFAHGHL_01497	6.45e-70	yjcN	-	-	-	-	-	-	-
MDFAHGHL_01499	3.65e-12	-	-	-	-	-	-	-	-
MDFAHGHL_01501	9.87e-70	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
MDFAHGHL_01502	7.48e-05	-	-	-	-	-	-	-	-
MDFAHGHL_01506	4.8e-07	-	-	-	-	-	-	-	-
MDFAHGHL_01507	1.53e-136	-	-	-	S	-	-	-	peptidoglycan catabolic process
MDFAHGHL_01509	2.16e-89	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDFAHGHL_01510	4.86e-46	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDFAHGHL_01511	6.02e-252	yubA	-	-	S	-	-	-	transporter activity
MDFAHGHL_01512	5.1e-84	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDFAHGHL_01513	2.83e-98	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDFAHGHL_01514	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MDFAHGHL_01515	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDFAHGHL_01516	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDFAHGHL_01517	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDFAHGHL_01519	1.73e-301	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDFAHGHL_01520	5.44e-180	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MDFAHGHL_01521	1.61e-55	-	-	-	-	-	-	-	-
MDFAHGHL_01522	2.44e-243	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MDFAHGHL_01523	1.83e-101	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MDFAHGHL_01524	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDFAHGHL_01525	1.9e-295	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDFAHGHL_01526	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MDFAHGHL_01527	1.24e-22	-	-	-	-	-	-	-	-
MDFAHGHL_01528	2.44e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MDFAHGHL_01529	8.37e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MDFAHGHL_01530	2.09e-95	yugN	-	-	S	-	-	-	YugN-like family
MDFAHGHL_01532	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MDFAHGHL_01533	3.94e-133	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MDFAHGHL_01534	2.15e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
MDFAHGHL_01535	1.37e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MDFAHGHL_01536	3.88e-285	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MDFAHGHL_01537	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MDFAHGHL_01538	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MDFAHGHL_01539	5.02e-268	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MDFAHGHL_01540	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01541	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
MDFAHGHL_01542	3.5e-54	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MDFAHGHL_01543	5.51e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MDFAHGHL_01544	1.49e-291	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01545	2.4e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MDFAHGHL_01546	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MDFAHGHL_01547	2.25e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MDFAHGHL_01548	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MDFAHGHL_01549	2.62e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01550	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MDFAHGHL_01551	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDFAHGHL_01552	4.81e-55	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MDFAHGHL_01553	6.69e-67	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MDFAHGHL_01554	2.88e-249	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MDFAHGHL_01555	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_01556	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDFAHGHL_01557	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDFAHGHL_01559	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDFAHGHL_01560	5.39e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDFAHGHL_01561	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDFAHGHL_01562	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDFAHGHL_01563	2.47e-101	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDFAHGHL_01564	1.1e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDFAHGHL_01565	1.21e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MDFAHGHL_01566	1.45e-85	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MDFAHGHL_01567	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_01568	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01570	8.68e-119	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
MDFAHGHL_01571	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
MDFAHGHL_01572	7.9e-72	yuzC	-	-	-	-	-	-	-
MDFAHGHL_01573	6.86e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MDFAHGHL_01574	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDFAHGHL_01575	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MDFAHGHL_01576	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MDFAHGHL_01577	9.09e-50	yueH	-	-	S	-	-	-	YueH-like protein
MDFAHGHL_01578	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MDFAHGHL_01579	1.88e-238	yueF	-	-	S	-	-	-	transporter activity
MDFAHGHL_01580	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MDFAHGHL_01581	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MDFAHGHL_01582	3.25e-166	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_01583	4.63e-101	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MDFAHGHL_01584	2.33e-282	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MDFAHGHL_01585	9.33e-225	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MDFAHGHL_01586	3.09e-38	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MDFAHGHL_01587	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDFAHGHL_01588	2.28e-275	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MDFAHGHL_01589	2.32e-51	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MDFAHGHL_01590	2.36e-61	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MDFAHGHL_01591	5.19e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
MDFAHGHL_01592	1.63e-260	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MDFAHGHL_01593	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MDFAHGHL_01594	2.73e-41	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MDFAHGHL_01595	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_01596	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_01597	5.21e-225	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MDFAHGHL_01598	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MDFAHGHL_01599	1.59e-285	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MDFAHGHL_01600	1.28e-173	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01601	3.61e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MDFAHGHL_01602	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MDFAHGHL_01603	2.37e-69	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MDFAHGHL_01604	4.25e-53	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MDFAHGHL_01605	2.01e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MDFAHGHL_01606	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MDFAHGHL_01607	1.43e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MDFAHGHL_01608	1.7e-153	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01609	2.45e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
MDFAHGHL_01610	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDFAHGHL_01611	1.03e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MDFAHGHL_01613	1.15e-237	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDFAHGHL_01614	5.68e-40	-	-	-	-	-	-	-	-
MDFAHGHL_01615	8.41e-93	-	-	-	CP	-	-	-	Membrane
MDFAHGHL_01616	6.82e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDFAHGHL_01618	1.62e-39	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
MDFAHGHL_01620	3.41e-121	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MDFAHGHL_01621	4.47e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01622	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MDFAHGHL_01623	5.54e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDFAHGHL_01624	1.22e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDFAHGHL_01625	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MDFAHGHL_01626	2.08e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDFAHGHL_01627	8.06e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01628	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MDFAHGHL_01629	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MDFAHGHL_01630	4.76e-217	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDFAHGHL_01631	1.62e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MDFAHGHL_01632	1.43e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MDFAHGHL_01633	7.66e-251	yutH	-	-	S	-	-	-	Spore coat protein
MDFAHGHL_01634	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MDFAHGHL_01635	5.03e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDFAHGHL_01636	7.66e-96	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MDFAHGHL_01637	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01638	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MDFAHGHL_01639	5.8e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MDFAHGHL_01640	4.76e-168	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MDFAHGHL_01641	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDFAHGHL_01642	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDFAHGHL_01643	1.58e-145	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MDFAHGHL_01644	5.25e-81	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MDFAHGHL_01645	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MDFAHGHL_01646	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MDFAHGHL_01649	9.57e-174	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
MDFAHGHL_01650	1.23e-273	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_01651	2.53e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MDFAHGHL_01652	1.3e-303	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MDFAHGHL_01653	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
MDFAHGHL_01654	1.35e-264	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_01655	4.84e-172	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MDFAHGHL_01656	4.31e-69	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MDFAHGHL_01657	6.37e-115	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MDFAHGHL_01658	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MDFAHGHL_01659	5.26e-203	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDFAHGHL_01660	4.28e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MDFAHGHL_01661	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MDFAHGHL_01662	2.01e-213	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDFAHGHL_01665	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MDFAHGHL_01666	3.7e-259	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MDFAHGHL_01667	1.72e-162	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MDFAHGHL_01668	5.28e-105	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MDFAHGHL_01669	3.07e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MDFAHGHL_01670	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MDFAHGHL_01671	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MDFAHGHL_01672	2.31e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDFAHGHL_01673	1.23e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MDFAHGHL_01674	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MDFAHGHL_01675	8.85e-85	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDFAHGHL_01676	4.46e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MDFAHGHL_01677	1.46e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MDFAHGHL_01678	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDFAHGHL_01679	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MDFAHGHL_01680	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
MDFAHGHL_01681	3.6e-81	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MDFAHGHL_01682	3.06e-28	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MDFAHGHL_01683	6.36e-09	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MDFAHGHL_01684	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MDFAHGHL_01685	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MDFAHGHL_01686	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MDFAHGHL_01687	9.03e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MDFAHGHL_01688	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MDFAHGHL_01689	2.9e-10	-	-	-	S	-	-	-	YuzL-like protein
MDFAHGHL_01690	1.12e-216	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MDFAHGHL_01691	2.25e-58	-	-	-	-	-	-	-	-
MDFAHGHL_01692	4.46e-72	yusN	-	-	M	-	-	-	Coat F domain
MDFAHGHL_01693	9.65e-92	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MDFAHGHL_01694	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MDFAHGHL_01695	1.57e-89	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MDFAHGHL_01696	1.27e-169	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01697	2.44e-206	yusT	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MDFAHGHL_01698	1.3e-207	-	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01699	1.87e-115	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MDFAHGHL_01700	2.23e-52	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MDFAHGHL_01701	1.46e-241	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDFAHGHL_01702	2.85e-51	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MDFAHGHL_01703	2.6e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDFAHGHL_01704	3.77e-60	-	-	-	S	-	-	-	YusW-like protein
MDFAHGHL_01705	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MDFAHGHL_01706	3.3e-198	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01707	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MDFAHGHL_01708	6.82e-308	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDFAHGHL_01709	3.17e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_01710	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01711	4.63e-33	-	-	-	-	-	-	-	-
MDFAHGHL_01712	3.11e-201	yuxN	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01713	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDFAHGHL_01714	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MDFAHGHL_01715	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MDFAHGHL_01716	4.56e-246	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MDFAHGHL_01717	1.04e-269	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MDFAHGHL_01718	3.22e-83	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_01719	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_01720	8.92e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MDFAHGHL_01721	7.09e-193	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MDFAHGHL_01722	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MDFAHGHL_01723	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MDFAHGHL_01724	1.43e-291	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_01725	3.23e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MDFAHGHL_01726	1.87e-289	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MDFAHGHL_01727	8.32e-233	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_01728	1.16e-215	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDFAHGHL_01729	4.99e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01730	9.15e-120	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MDFAHGHL_01731	3.21e-50	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MDFAHGHL_01732	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MDFAHGHL_01733	2.7e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_01734	1.67e-50	-	-	-	-	-	-	-	-
MDFAHGHL_01735	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MDFAHGHL_01736	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
MDFAHGHL_01737	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MDFAHGHL_01738	4.84e-88	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MDFAHGHL_01739	1.33e-186	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDFAHGHL_01740	1.17e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_01741	3.29e-238	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_01742	2.21e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDFAHGHL_01743	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MDFAHGHL_01744	1.06e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MDFAHGHL_01745	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MDFAHGHL_01746	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MDFAHGHL_01747	7e-214	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MDFAHGHL_01748	6.8e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MDFAHGHL_01749	1.92e-123	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MDFAHGHL_01750	4.32e-148	yfiK	-	-	K	-	-	-	Regulator
MDFAHGHL_01751	8.26e-251	-	-	-	T	-	-	-	Histidine kinase
MDFAHGHL_01752	4.97e-220	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MDFAHGHL_01753	3.65e-251	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MDFAHGHL_01754	4.66e-258	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MDFAHGHL_01755	1.77e-200	yvgN	-	-	S	-	-	-	reductase
MDFAHGHL_01756	1.38e-113	yvgO	-	-	-	-	-	-	-
MDFAHGHL_01757	2.52e-176	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MDFAHGHL_01758	2.51e-207	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MDFAHGHL_01759	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MDFAHGHL_01760	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MDFAHGHL_01761	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDFAHGHL_01762	2.24e-139	yvgT	-	-	S	-	-	-	membrane
MDFAHGHL_01763	2.05e-185	-	-	-	S	-	-	-	Metallo-peptidase family M12
MDFAHGHL_01764	7.48e-96	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MDFAHGHL_01765	8.75e-136	bdbD	-	-	O	-	-	-	Thioredoxin
MDFAHGHL_01766	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MDFAHGHL_01767	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MDFAHGHL_01768	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MDFAHGHL_01769	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MDFAHGHL_01770	8.97e-252	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MDFAHGHL_01771	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDFAHGHL_01772	4.39e-209	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDFAHGHL_01773	2.63e-283	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDFAHGHL_01774	2.61e-91	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDFAHGHL_01775	3.56e-188	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MDFAHGHL_01776	7.6e-300	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_01777	2.9e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MDFAHGHL_01778	9.08e-235	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_01779	9e-181	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDFAHGHL_01780	8.24e-156	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDFAHGHL_01781	1.04e-156	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDFAHGHL_01782	3.69e-190	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MDFAHGHL_01783	4.15e-168	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MDFAHGHL_01784	3.16e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDFAHGHL_01785	6.64e-211	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MDFAHGHL_01786	1.87e-178	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MDFAHGHL_01787	1.1e-70	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MDFAHGHL_01789	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MDFAHGHL_01790	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDFAHGHL_01791	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MDFAHGHL_01792	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MDFAHGHL_01793	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
MDFAHGHL_01794	1.58e-91	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MDFAHGHL_01795	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDFAHGHL_01796	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
MDFAHGHL_01797	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MDFAHGHL_01798	4.69e-159	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MDFAHGHL_01799	3.96e-176	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDFAHGHL_01800	1.53e-160	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MDFAHGHL_01801	1.88e-162	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_01802	3.47e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDFAHGHL_01803	7.98e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDFAHGHL_01804	2.39e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDFAHGHL_01805	4.07e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDFAHGHL_01806	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MDFAHGHL_01807	2.64e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDFAHGHL_01808	9.31e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDFAHGHL_01809	3.79e-122	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MDFAHGHL_01810	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDFAHGHL_01811	1.01e-129	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MDFAHGHL_01812	7.67e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MDFAHGHL_01813	3.1e-156	yvbI	-	-	M	-	-	-	Membrane
MDFAHGHL_01814	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MDFAHGHL_01815	1.11e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MDFAHGHL_01816	5.65e-272	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MDFAHGHL_01817	1.69e-229	-	-	-	-	-	-	-	-
MDFAHGHL_01818	1.83e-161	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MDFAHGHL_01819	2.89e-185	-	-	-	C	-	-	-	WbqC-like protein family
MDFAHGHL_01820	1.31e-190	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
MDFAHGHL_01821	1.93e-303	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MDFAHGHL_01822	4.25e-220	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
MDFAHGHL_01823	2.45e-137	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MDFAHGHL_01824	1.43e-126	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MDFAHGHL_01825	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDFAHGHL_01826	1.86e-307	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MDFAHGHL_01827	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDFAHGHL_01828	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MDFAHGHL_01829	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDFAHGHL_01830	1.62e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MDFAHGHL_01831	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDFAHGHL_01832	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDFAHGHL_01834	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDFAHGHL_01835	6.68e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MDFAHGHL_01836	1.25e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_01838	3.25e-195	yvbU	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01839	6.36e-204	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MDFAHGHL_01840	6.69e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_01841	0.0	-	-	-	-	-	-	-	-
MDFAHGHL_01842	4.5e-234	yhjM	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01843	2.2e-149	-	-	-	S	ko:K07149	-	ko00000	Membrane
MDFAHGHL_01844	6.26e-215	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDFAHGHL_01846	1.14e-196	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
MDFAHGHL_01847	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MDFAHGHL_01848	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MDFAHGHL_01849	1.23e-173	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDFAHGHL_01850	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MDFAHGHL_01851	9.19e-162	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDFAHGHL_01852	1.42e-287	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDFAHGHL_01853	3.1e-156	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MDFAHGHL_01854	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MDFAHGHL_01855	4.13e-312	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MDFAHGHL_01856	9.82e-45	yvfG	-	-	S	-	-	-	YvfG protein
MDFAHGHL_01857	2.08e-242	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MDFAHGHL_01858	7.8e-282	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MDFAHGHL_01859	7.03e-80	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MDFAHGHL_01860	9.52e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDFAHGHL_01861	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_01862	3.12e-251	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDFAHGHL_01863	5.24e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MDFAHGHL_01864	7.95e-250	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MDFAHGHL_01865	1.46e-263	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MDFAHGHL_01866	1.74e-272	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MDFAHGHL_01867	2.74e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDFAHGHL_01868	7.76e-281	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MDFAHGHL_01869	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MDFAHGHL_01870	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MDFAHGHL_01871	4.76e-155	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MDFAHGHL_01872	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MDFAHGHL_01873	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MDFAHGHL_01875	1.7e-128	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MDFAHGHL_01876	1.06e-145	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MDFAHGHL_01877	1.15e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDFAHGHL_01878	2.47e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MDFAHGHL_01879	1.14e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MDFAHGHL_01880	2.02e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MDFAHGHL_01881	6.27e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MDFAHGHL_01882	6.21e-303	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MDFAHGHL_01883	3.92e-47	-	-	-	-	-	-	-	-
MDFAHGHL_01885	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDFAHGHL_01886	1.65e-284	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MDFAHGHL_01887	6.67e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MDFAHGHL_01888	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDFAHGHL_01889	1.93e-209	yraN	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01890	6.58e-276	yraM	-	-	S	-	-	-	PrpF protein
MDFAHGHL_01891	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MDFAHGHL_01892	7.64e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MDFAHGHL_01893	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MDFAHGHL_01894	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MDFAHGHL_01895	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MDFAHGHL_01896	2.51e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDFAHGHL_01897	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
MDFAHGHL_01898	1.95e-136	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MDFAHGHL_01899	9.28e-26	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MDFAHGHL_01900	2.76e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MDFAHGHL_01901	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MDFAHGHL_01902	8.99e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MDFAHGHL_01903	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MDFAHGHL_01904	4.94e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MDFAHGHL_01905	3.13e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDFAHGHL_01906	2.16e-174	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MDFAHGHL_01908	2.49e-312	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MDFAHGHL_01909	3.35e-246	sasA	-	-	T	-	-	-	Histidine kinase
MDFAHGHL_01910	1.6e-157	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_01911	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MDFAHGHL_01912	1.4e-144	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MDFAHGHL_01913	3.4e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDFAHGHL_01914	2.78e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MDFAHGHL_01915	2.41e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDFAHGHL_01916	6.76e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MDFAHGHL_01917	1.35e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDFAHGHL_01918	1.83e-148	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MDFAHGHL_01919	6.03e-270	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MDFAHGHL_01920	3.56e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MDFAHGHL_01921	3.16e-108	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MDFAHGHL_01922	8.12e-158	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MDFAHGHL_01923	1.84e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDFAHGHL_01924	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDFAHGHL_01925	2.45e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDFAHGHL_01926	5.45e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDFAHGHL_01927	4.29e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MDFAHGHL_01928	4.24e-134	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MDFAHGHL_01929	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MDFAHGHL_01930	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MDFAHGHL_01931	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MDFAHGHL_01932	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
MDFAHGHL_01933	4.87e-66	yvlA	-	-	-	-	-	-	-
MDFAHGHL_01934	8.07e-44	yvkN	-	-	-	-	-	-	-
MDFAHGHL_01935	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDFAHGHL_01936	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDFAHGHL_01937	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01938	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MDFAHGHL_01939	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01940	2.41e-297	yvkA	-	-	P	-	-	-	-transporter
MDFAHGHL_01941	3.46e-237	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MDFAHGHL_01942	9.15e-284	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDFAHGHL_01943	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MDFAHGHL_01944	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MDFAHGHL_01945	3.11e-307	ywoF	-	-	P	-	-	-	Right handed beta helix region
MDFAHGHL_01946	7.34e-197	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MDFAHGHL_01947	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MDFAHGHL_01948	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MDFAHGHL_01949	4.82e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_01950	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDFAHGHL_01951	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDFAHGHL_01952	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDFAHGHL_01953	1.35e-89	-	-	-	-	-	-	-	-
MDFAHGHL_01954	9.83e-12	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MDFAHGHL_01955	8.23e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MDFAHGHL_01956	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MDFAHGHL_01957	8.13e-137	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDFAHGHL_01958	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MDFAHGHL_01959	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MDFAHGHL_01960	2.8e-108	yviE	-	-	-	-	-	-	-
MDFAHGHL_01961	1.2e-208	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MDFAHGHL_01962	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MDFAHGHL_01963	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
MDFAHGHL_01964	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MDFAHGHL_01965	5.47e-98	yvyF	-	-	S	-	-	-	flagellar protein
MDFAHGHL_01966	3.53e-100	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MDFAHGHL_01967	2.14e-58	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MDFAHGHL_01968	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MDFAHGHL_01969	8.81e-204	degV	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_01970	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_01971	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MDFAHGHL_01972	1.2e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MDFAHGHL_01973	2.6e-240	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_01974	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MDFAHGHL_01975	4.67e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MDFAHGHL_01976	6.92e-186	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MDFAHGHL_01977	2.99e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MDFAHGHL_01978	5.65e-26	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MDFAHGHL_01979	1.17e-44	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MDFAHGHL_01980	2.51e-213	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MDFAHGHL_01981	3.1e-308	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDFAHGHL_01982	6.46e-285	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MDFAHGHL_01983	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_01984	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDFAHGHL_01985	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MDFAHGHL_01986	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MDFAHGHL_01987	1.31e-64	-	-	-	-	-	-	-	-
MDFAHGHL_01988	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MDFAHGHL_01989	1.88e-272	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDFAHGHL_01990	2.64e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDFAHGHL_01991	1.02e-85	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDFAHGHL_01992	2.81e-245	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDFAHGHL_01993	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MDFAHGHL_01994	9.62e-210	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDFAHGHL_01995	2.3e-303	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDFAHGHL_01996	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDFAHGHL_01997	2.01e-55	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MDFAHGHL_01998	1.5e-26	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MDFAHGHL_01999	3.69e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDFAHGHL_02000	3.04e-278	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDFAHGHL_02001	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDFAHGHL_02002	9.91e-243	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDFAHGHL_02003	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MDFAHGHL_02004	2.69e-255	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MDFAHGHL_02005	3.13e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MDFAHGHL_02006	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
MDFAHGHL_02007	4.54e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDFAHGHL_02008	9.77e-231	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02009	1.3e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDFAHGHL_02010	1.28e-79	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MDFAHGHL_02011	3.32e-305	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDFAHGHL_02012	4.04e-29	ywtC	-	-	-	-	-	-	-
MDFAHGHL_02013	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MDFAHGHL_02014	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MDFAHGHL_02015	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MDFAHGHL_02017	1.98e-90	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MDFAHGHL_02018	1.15e-159	-	-	-	P	ko:K06295	-	ko00000	Bacillus/Clostridium GerA spore germination protein
MDFAHGHL_02019	1.79e-246	-	-	-	E	-	-	-	Spore germination protein
MDFAHGHL_02020	2.25e-263	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MDFAHGHL_02021	4.28e-228	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MDFAHGHL_02022	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDFAHGHL_02023	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDFAHGHL_02024	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MDFAHGHL_02025	1.87e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDFAHGHL_02026	6.93e-208	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MDFAHGHL_02027	2.91e-116	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MDFAHGHL_02028	3.53e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MDFAHGHL_02029	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MDFAHGHL_02030	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MDFAHGHL_02031	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
MDFAHGHL_02033	7.35e-307	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDFAHGHL_02034	3.43e-163	ywrJ	-	-	-	-	-	-	-
MDFAHGHL_02035	2.24e-186	cotB	-	-	-	ko:K06325	-	ko00000	-
MDFAHGHL_02036	5.57e-271	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MDFAHGHL_02037	3.57e-21	-	-	-	-	-	-	-	-
MDFAHGHL_02038	6.96e-145	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MDFAHGHL_02040	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MDFAHGHL_02041	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MDFAHGHL_02042	4.91e-131	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MDFAHGHL_02043	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MDFAHGHL_02044	3.04e-173	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MDFAHGHL_02045	9.61e-121	-	-	-	-	-	-	-	-
MDFAHGHL_02046	1.39e-25	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
MDFAHGHL_02047	7.22e-60	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
MDFAHGHL_02048	6.26e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF1851)
MDFAHGHL_02049	8.26e-81	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MDFAHGHL_02050	1.42e-132	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MDFAHGHL_02051	3.45e-118	-	-	-	-	-	-	-	-
MDFAHGHL_02052	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MDFAHGHL_02053	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MDFAHGHL_02056	1.84e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MDFAHGHL_02057	5.28e-315	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDFAHGHL_02058	6.38e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MDFAHGHL_02059	2.69e-158	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MDFAHGHL_02060	3.53e-152	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MDFAHGHL_02061	1.74e-21	-	-	-	-	-	-	-	-
MDFAHGHL_02062	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MDFAHGHL_02063	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDFAHGHL_02064	2.15e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MDFAHGHL_02065	5.59e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MDFAHGHL_02066	1.47e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MDFAHGHL_02067	4.49e-82	ywpG	-	-	-	-	-	-	-
MDFAHGHL_02068	9.16e-91	ywpF	-	-	S	-	-	-	YwpF-like protein
MDFAHGHL_02069	1.87e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDFAHGHL_02070	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDFAHGHL_02071	1.63e-258	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MDFAHGHL_02072	1.14e-188	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MDFAHGHL_02073	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MDFAHGHL_02074	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MDFAHGHL_02075	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MDFAHGHL_02076	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
MDFAHGHL_02077	2.89e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_02078	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MDFAHGHL_02079	2.81e-312	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MDFAHGHL_02080	5.6e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MDFAHGHL_02081	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MDFAHGHL_02082	3.71e-76	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MDFAHGHL_02083	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDFAHGHL_02084	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MDFAHGHL_02085	4.67e-95	ywnJ	-	-	S	-	-	-	VanZ like family
MDFAHGHL_02086	1.31e-188	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MDFAHGHL_02087	7.91e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MDFAHGHL_02089	2.55e-90	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MDFAHGHL_02090	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDFAHGHL_02091	1.97e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MDFAHGHL_02092	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MDFAHGHL_02093	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02094	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MDFAHGHL_02095	1.07e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MDFAHGHL_02096	2.35e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MDFAHGHL_02097	2.01e-16	csbD	-	-	K	-	-	-	CsbD-like
MDFAHGHL_02098	3.66e-108	ywmF	-	-	S	-	-	-	Peptidase M50
MDFAHGHL_02099	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDFAHGHL_02100	1.31e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MDFAHGHL_02101	1.29e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MDFAHGHL_02103	1.5e-158	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDFAHGHL_02104	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MDFAHGHL_02105	5.75e-242	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MDFAHGHL_02106	2.02e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDFAHGHL_02107	8.35e-175	ywmB	-	-	S	-	-	-	TATA-box binding
MDFAHGHL_02108	2.25e-45	ywzB	-	-	S	-	-	-	membrane
MDFAHGHL_02109	1.76e-118	ywmA	-	-	-	-	-	-	-
MDFAHGHL_02110	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MDFAHGHL_02111	1.8e-188	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDFAHGHL_02112	1.29e-105	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDFAHGHL_02113	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDFAHGHL_02114	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDFAHGHL_02115	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDFAHGHL_02116	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDFAHGHL_02117	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDFAHGHL_02118	3e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MDFAHGHL_02119	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MDFAHGHL_02120	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDFAHGHL_02121	1.7e-300	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDFAHGHL_02122	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MDFAHGHL_02123	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MDFAHGHL_02124	2.08e-101	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDFAHGHL_02125	1.66e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MDFAHGHL_02126	1.31e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDFAHGHL_02127	5.15e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MDFAHGHL_02128	1.38e-154	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MDFAHGHL_02129	9.92e-78	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MDFAHGHL_02131	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDFAHGHL_02132	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDFAHGHL_02133	3.56e-86	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02134	1.04e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MDFAHGHL_02135	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MDFAHGHL_02136	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MDFAHGHL_02137	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MDFAHGHL_02138	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MDFAHGHL_02139	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDFAHGHL_02140	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MDFAHGHL_02141	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDFAHGHL_02142	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDFAHGHL_02143	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MDFAHGHL_02144	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MDFAHGHL_02145	2.72e-119	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MDFAHGHL_02146	4.1e-230	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDFAHGHL_02147	2.21e-112	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDFAHGHL_02148	8.35e-67	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDFAHGHL_02149	9.17e-38	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MDFAHGHL_02150	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MDFAHGHL_02151	2.18e-288	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MDFAHGHL_02152	5.7e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MDFAHGHL_02153	7.93e-59	ywjC	-	-	-	-	-	-	-
MDFAHGHL_02154	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDFAHGHL_02155	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDFAHGHL_02156	1.75e-135	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDFAHGHL_02157	1.45e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MDFAHGHL_02158	1.13e-126	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MDFAHGHL_02159	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MDFAHGHL_02160	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDFAHGHL_02161	2.49e-110	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MDFAHGHL_02162	8.75e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
MDFAHGHL_02163	1.33e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MDFAHGHL_02164	1.05e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MDFAHGHL_02165	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MDFAHGHL_02166	1.14e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02168	8.09e-314	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MDFAHGHL_02169	8.1e-299	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MDFAHGHL_02170	1.16e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDFAHGHL_02172	9.15e-41	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
MDFAHGHL_02173	2.41e-45	-	-	-	-	-	-	-	-
MDFAHGHL_02174	1.18e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MDFAHGHL_02176	5.95e-101	-	-	-	CP	-	-	-	Membrane
MDFAHGHL_02179	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MDFAHGHL_02180	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MDFAHGHL_02181	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDFAHGHL_02182	2.57e-107	-	-	-	-	-	-	-	-
MDFAHGHL_02183	3.32e-124	ywhD	-	-	S	-	-	-	YwhD family
MDFAHGHL_02184	9.43e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MDFAHGHL_02185	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MDFAHGHL_02186	1.02e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02187	2.71e-316	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
MDFAHGHL_02188	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MDFAHGHL_02189	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MDFAHGHL_02190	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MDFAHGHL_02191	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MDFAHGHL_02192	5.36e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MDFAHGHL_02193	3.23e-121	-	-	-	S	-	-	-	membrane
MDFAHGHL_02194	8.51e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02195	1.4e-213	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MDFAHGHL_02198	4.7e-238	-	-	-	-	-	-	-	-
MDFAHGHL_02200	1.58e-204	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MDFAHGHL_02201	2.25e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_02202	2.93e-214	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MDFAHGHL_02203	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MDFAHGHL_02204	2.82e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MDFAHGHL_02205	1.7e-180	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_02206	1.56e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MDFAHGHL_02207	8.14e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MDFAHGHL_02208	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MDFAHGHL_02209	8.05e-181	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_02210	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MDFAHGHL_02211	1.4e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MDFAHGHL_02212	4.24e-288	ywfA	-	-	EGP	-	-	-	-transporter
MDFAHGHL_02213	2.83e-264	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MDFAHGHL_02214	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDFAHGHL_02215	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MDFAHGHL_02216	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDFAHGHL_02217	9.01e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MDFAHGHL_02218	6.37e-207	-	-	-	T	-	-	-	Histidine kinase
MDFAHGHL_02219	2.59e-162	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_02220	2.37e-96	-	-	-	-	-	-	-	-
MDFAHGHL_02221	1.21e-152	-	-	-	S	-	-	-	ABC-2 family transporter protein
MDFAHGHL_02222	2.28e-222	bcrA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02223	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MDFAHGHL_02224	2.86e-209	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDFAHGHL_02225	1.83e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDFAHGHL_02226	9.8e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDFAHGHL_02227	6.44e-239	spsG	-	-	M	-	-	-	Spore Coat
MDFAHGHL_02228	1.05e-175	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MDFAHGHL_02229	1.23e-274	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MDFAHGHL_02230	4.04e-207	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MDFAHGHL_02231	5.29e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MDFAHGHL_02232	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MDFAHGHL_02233	1.29e-183	spsA	-	-	M	-	-	-	Spore Coat
MDFAHGHL_02234	1.49e-89	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MDFAHGHL_02235	3.75e-77	ywdK	-	-	S	-	-	-	small membrane protein
MDFAHGHL_02236	2.01e-294	ywdJ	-	-	F	-	-	-	Xanthine uracil
MDFAHGHL_02237	3.7e-61	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MDFAHGHL_02238	5.93e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDFAHGHL_02239	2.42e-194	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MDFAHGHL_02241	3.46e-116	ywdD	-	-	-	-	-	-	-
MDFAHGHL_02242	1.6e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MDFAHGHL_02243	4.13e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDFAHGHL_02244	3.52e-26	ywdA	-	-	-	-	-	-	-
MDFAHGHL_02245	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDFAHGHL_02246	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02247	5.46e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MDFAHGHL_02249	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDFAHGHL_02250	1.15e-236	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_02251	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MDFAHGHL_02252	1.58e-263	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MDFAHGHL_02253	6.39e-102	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MDFAHGHL_02254	1.03e-50	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MDFAHGHL_02255	1.6e-82	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MDFAHGHL_02256	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MDFAHGHL_02257	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDFAHGHL_02258	1.47e-68	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDFAHGHL_02259	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MDFAHGHL_02260	5.74e-48	ydaS	-	-	S	-	-	-	membrane
MDFAHGHL_02261	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDFAHGHL_02262	5.5e-117	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDFAHGHL_02263	5.13e-146	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDFAHGHL_02264	3.45e-81	gtcA	-	-	S	-	-	-	GtrA-like protein
MDFAHGHL_02265	6.43e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDFAHGHL_02267	7.5e-168	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MDFAHGHL_02268	1.71e-172	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
MDFAHGHL_02269	3.09e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDFAHGHL_02270	2.98e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MDFAHGHL_02271	1.22e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDFAHGHL_02272	2.04e-95	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDFAHGHL_02273	3.57e-54	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDFAHGHL_02274	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02275	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MDFAHGHL_02276	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MDFAHGHL_02277	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MDFAHGHL_02278	5.9e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MDFAHGHL_02279	4.26e-220	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MDFAHGHL_02280	7.26e-285	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MDFAHGHL_02281	1.29e-88	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MDFAHGHL_02282	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDFAHGHL_02283	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDFAHGHL_02284	6.3e-209	gspA	-	-	M	-	-	-	General stress
MDFAHGHL_02285	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MDFAHGHL_02286	7.57e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MDFAHGHL_02287	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MDFAHGHL_02288	3.78e-204	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02289	1.33e-120	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02290	1.04e-292	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MDFAHGHL_02291	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02292	1.31e-290	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDFAHGHL_02293	5.72e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MDFAHGHL_02294	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDFAHGHL_02295	2.9e-68	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02296	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDFAHGHL_02297	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MDFAHGHL_02298	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MDFAHGHL_02299	5.36e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MDFAHGHL_02300	1.15e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_02301	4.83e-231	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_02302	9.23e-214	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MDFAHGHL_02303	3.3e-79	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MDFAHGHL_02304	6.3e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDFAHGHL_02305	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02306	6.75e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02307	7.31e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDFAHGHL_02308	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_02309	4.13e-92	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MDFAHGHL_02310	6.26e-111	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MDFAHGHL_02311	2.17e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDFAHGHL_02312	7.88e-269	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MDFAHGHL_02313	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDFAHGHL_02314	2.26e-245	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MDFAHGHL_02315	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MDFAHGHL_02316	1.07e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDFAHGHL_02317	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MDFAHGHL_02318	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MDFAHGHL_02319	9.56e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MDFAHGHL_02320	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MDFAHGHL_02321	4.75e-289	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MDFAHGHL_02322	3.03e-151	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MDFAHGHL_02323	2.04e-22	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MDFAHGHL_02324	1.51e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_02325	2.66e-217	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MDFAHGHL_02326	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDFAHGHL_02327	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MDFAHGHL_02328	1.61e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDFAHGHL_02329	1.2e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDFAHGHL_02332	7.42e-112	yxjI	-	-	S	-	-	-	LURP-one-related
MDFAHGHL_02333	9.77e-279	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MDFAHGHL_02334	6.25e-98	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MDFAHGHL_02335	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDFAHGHL_02336	3.75e-126	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MDFAHGHL_02337	4.1e-66	yxiS	-	-	-	-	-	-	-
MDFAHGHL_02339	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDFAHGHL_02340	2.33e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MDFAHGHL_02341	8.45e-187	bglS	-	-	M	-	-	-	licheninase activity
MDFAHGHL_02342	1.19e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MDFAHGHL_02343	2.21e-283	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MDFAHGHL_02344	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MDFAHGHL_02346	5.37e-27	-	-	-	-	-	-	-	-
MDFAHGHL_02349	2.73e-100	-	-	-	-	-	-	-	-
MDFAHGHL_02353	4.73e-97	yxiG	-	-	-	-	-	-	-
MDFAHGHL_02354	3.88e-92	yxxG	-	-	-	-	-	-	-
MDFAHGHL_02356	6.36e-256	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MDFAHGHL_02357	1.78e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MDFAHGHL_02358	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MDFAHGHL_02359	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_02360	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02363	0.000685	-	-	-	K	-	-	-	Cupin 2, conserved barrel domain protein
MDFAHGHL_02364	1.56e-172	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
MDFAHGHL_02365	4.28e-156	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MDFAHGHL_02366	2.45e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MDFAHGHL_02367	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MDFAHGHL_02368	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MDFAHGHL_02369	5.73e-302	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MDFAHGHL_02370	2.04e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MDFAHGHL_02371	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDFAHGHL_02372	1.1e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MDFAHGHL_02373	1.16e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDFAHGHL_02374	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDFAHGHL_02375	1e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDFAHGHL_02376	2.32e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MDFAHGHL_02379	2.06e-42	yxeE	-	-	-	-	-	-	-
MDFAHGHL_02380	5.09e-35	yxeD	-	-	-	-	-	-	-
MDFAHGHL_02381	8.01e-46	-	-	-	-	-	-	-	-
MDFAHGHL_02382	1.06e-230	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MDFAHGHL_02383	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MDFAHGHL_02384	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MDFAHGHL_02385	4.65e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02386	6.81e-225	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_02387	5.65e-160	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_02388	1.4e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MDFAHGHL_02389	4.18e-201	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MDFAHGHL_02390	2.54e-211	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MDFAHGHL_02391	7.67e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDFAHGHL_02392	7.75e-296	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MDFAHGHL_02393	1.18e-225	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MDFAHGHL_02394	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MDFAHGHL_02395	2.92e-233	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MDFAHGHL_02396	5.96e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MDFAHGHL_02397	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDFAHGHL_02398	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDFAHGHL_02399	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MDFAHGHL_02400	1.1e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDFAHGHL_02401	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MDFAHGHL_02403	6.15e-195	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_02404	7.82e-134	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_02405	1.01e-255	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_02406	3.84e-259	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MDFAHGHL_02407	1.02e-279	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDFAHGHL_02408	3.07e-306	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDFAHGHL_02409	4.13e-190	yxaL	-	-	S	-	-	-	PQQ-like domain
MDFAHGHL_02410	4.84e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MDFAHGHL_02411	4.06e-66	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDFAHGHL_02412	3.98e-258	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDFAHGHL_02413	9.49e-98	yxaI	-	-	S	-	-	-	membrane protein domain
MDFAHGHL_02414	3.42e-165	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
MDFAHGHL_02415	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MDFAHGHL_02416	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MDFAHGHL_02417	3.39e-293	-	-	-	S	-	-	-	Fic/DOC family
MDFAHGHL_02418	5.04e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_02419	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MDFAHGHL_02420	3.87e-111	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MDFAHGHL_02421	2.71e-197	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MDFAHGHL_02422	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MDFAHGHL_02423	4.94e-124	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MDFAHGHL_02424	2.86e-244	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MDFAHGHL_02425	2.32e-236	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MDFAHGHL_02426	0.0	-	-	-	L	-	-	-	AAA domain
MDFAHGHL_02427	2.36e-312	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MDFAHGHL_02428	4.99e-143	-	-	-	-	-	-	-	-
MDFAHGHL_02429	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDFAHGHL_02432	8.39e-280	yycP	-	-	-	-	-	-	-
MDFAHGHL_02433	1.43e-172	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MDFAHGHL_02434	3.31e-237	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MDFAHGHL_02435	5.89e-113	yycN	-	-	K	-	-	-	Acetyltransferase
MDFAHGHL_02437	9.49e-262	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MDFAHGHL_02438	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MDFAHGHL_02439	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDFAHGHL_02440	6.09e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MDFAHGHL_02441	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MDFAHGHL_02442	4.53e-189	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
MDFAHGHL_02443	0.0	-	-	-	S	-	-	-	ABC transporter
MDFAHGHL_02444	1.85e-252	-	-	-	S	-	-	-	Major Facilitator Superfamily
MDFAHGHL_02445	0.0	-	-	-	-	-	-	-	-
MDFAHGHL_02446	2.51e-245	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MDFAHGHL_02447	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MDFAHGHL_02448	9.23e-14	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_02449	1.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDFAHGHL_02450	9.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MDFAHGHL_02451	1.77e-197	yycI	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02452	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02453	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_02454	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_02459	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDFAHGHL_02460	1.65e-60	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02461	2.89e-18	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02462	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MDFAHGHL_02463	1.88e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MDFAHGHL_02465	5.12e-25	yycC	-	-	K	-	-	-	YycC-like protein
MDFAHGHL_02466	5.22e-52	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
MDFAHGHL_02467	1.24e-171	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MDFAHGHL_02468	1.68e-108	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MDFAHGHL_02469	3.16e-259	-	-	-	S	-	-	-	Ecdysteroid kinase
MDFAHGHL_02470	3.96e-298	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
MDFAHGHL_02471	9.36e-317	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MDFAHGHL_02472	1.85e-158	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MDFAHGHL_02473	8.75e-160	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
MDFAHGHL_02474	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MDFAHGHL_02475	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MDFAHGHL_02476	2.73e-120	yybS	-	-	S	-	-	-	membrane
MDFAHGHL_02477	2.8e-65	yybS	-	-	S	-	-	-	membrane
MDFAHGHL_02479	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MDFAHGHL_02480	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02481	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MDFAHGHL_02482	3.54e-198	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDFAHGHL_02483	5.64e-220	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MDFAHGHL_02484	7.02e-117	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MDFAHGHL_02485	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MDFAHGHL_02486	2.4e-152	-	-	-	K	-	-	-	FCD domain
MDFAHGHL_02487	7.11e-118	-	-	-	S	-	-	-	PFAM DinB family protein
MDFAHGHL_02488	3.32e-204	-	-	-	G	-	-	-	Major Facilitator Superfamily
MDFAHGHL_02489	6.22e-209	-	-	-	K	-	-	-	LysR substrate binding domain
MDFAHGHL_02490	1.13e-129	-	-	-	E	-	-	-	LysE type translocator
MDFAHGHL_02491	7.42e-276	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_02492	7.58e-212	yybE	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02493	1.21e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MDFAHGHL_02494	1.7e-148	ydgI	-	-	C	-	-	-	nitroreductase
MDFAHGHL_02495	3.36e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MDFAHGHL_02496	3.4e-197	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_02497	1.3e-99	yybA	-	-	K	-	-	-	transcriptional
MDFAHGHL_02498	3.81e-100	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_02499	3.23e-180	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
MDFAHGHL_02501	7.04e-89	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MDFAHGHL_02502	6.24e-214	-	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02503	3.96e-184	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MDFAHGHL_02504	7.43e-130	-	-	-	-	-	-	-	-
MDFAHGHL_02505	3.55e-36	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MDFAHGHL_02506	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2326)
MDFAHGHL_02507	2.01e-74	-	-	-	-	-	-	-	-
MDFAHGHL_02508	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDFAHGHL_02510	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MDFAHGHL_02511	1.11e-59	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MDFAHGHL_02512	3.6e-211	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDFAHGHL_02513	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MDFAHGHL_02514	5.93e-89	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02515	1.84e-232	ccpB	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02516	2.51e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDFAHGHL_02517	7.39e-132	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDFAHGHL_02518	3.59e-125	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MDFAHGHL_02519	9.65e-36	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDFAHGHL_02520	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDFAHGHL_02521	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MDFAHGHL_02522	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDFAHGHL_02523	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDFAHGHL_02524	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02525	4.54e-170	yyaD	-	-	S	-	-	-	Membrane
MDFAHGHL_02526	2.08e-111	yhhY	-	-	K	-	-	-	FR47-like protein
MDFAHGHL_02527	2.84e-143	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MDFAHGHL_02528	1.23e-190	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDFAHGHL_02529	1.23e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MDFAHGHL_02530	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MDFAHGHL_02531	3.25e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MDFAHGHL_02532	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDFAHGHL_02533	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDFAHGHL_02534	1.14e-142	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MDFAHGHL_02535	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDFAHGHL_02536	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDFAHGHL_02537	2.77e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MDFAHGHL_02538	1.31e-87	tmrB	-	-	S	-	-	-	AAA domain
MDFAHGHL_02539	2.82e-190	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MDFAHGHL_02540	5.54e-303	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_02541	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MDFAHGHL_02542	4.68e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MDFAHGHL_02543	1.51e-189	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MDFAHGHL_02544	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MDFAHGHL_02545	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDFAHGHL_02546	1.81e-310	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDFAHGHL_02547	1.17e-225	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MDFAHGHL_02548	1.85e-51	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MDFAHGHL_02549	3.33e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MDFAHGHL_02550	1.43e-127	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MDFAHGHL_02551	2.4e-210	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MDFAHGHL_02552	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MDFAHGHL_02553	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDFAHGHL_02554	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDFAHGHL_02555	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MDFAHGHL_02556	2.01e-285	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MDFAHGHL_02557	4.25e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
MDFAHGHL_02558	7.48e-283	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDFAHGHL_02559	9.31e-97	yckC	-	-	S	-	-	-	membrane
MDFAHGHL_02560	5.5e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MDFAHGHL_02561	2.21e-212	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_02562	9.11e-112	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_02563	5.81e-92	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MDFAHGHL_02564	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MDFAHGHL_02565	2.67e-125	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MDFAHGHL_02566	3.14e-139	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MDFAHGHL_02567	1.01e-84	hxlR	-	-	K	-	-	-	transcriptional
MDFAHGHL_02568	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02569	1.13e-65	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02570	4.59e-289	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02571	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02572	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDFAHGHL_02573	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MDFAHGHL_02574	3.05e-180	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MDFAHGHL_02575	1.91e-316	-	-	-	E	-	-	-	Aminotransferase class I and II
MDFAHGHL_02576	2.38e-86	-	-	-	S	-	-	-	YcxB-like protein
MDFAHGHL_02577	9.63e-193	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MDFAHGHL_02578	5.05e-315	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MDFAHGHL_02579	1.11e-168	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MDFAHGHL_02580	3.11e-144	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MDFAHGHL_02581	8.3e-171	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MDFAHGHL_02582	4.99e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDFAHGHL_02583	5.85e-144	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MDFAHGHL_02584	6.95e-205	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MDFAHGHL_02585	1.4e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MDFAHGHL_02586	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MDFAHGHL_02587	1.64e-51	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MDFAHGHL_02588	1.01e-101	yclD	-	-	-	-	-	-	-
MDFAHGHL_02589	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MDFAHGHL_02590	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MDFAHGHL_02592	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MDFAHGHL_02593	4e-300	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MDFAHGHL_02594	2.27e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MDFAHGHL_02595	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDFAHGHL_02596	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDFAHGHL_02597	1.56e-183	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MDFAHGHL_02598	2.46e-147	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MDFAHGHL_02599	1.38e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02600	2.5e-279	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MDFAHGHL_02601	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MDFAHGHL_02602	4.84e-160	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MDFAHGHL_02603	0.0	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MDFAHGHL_02604	9.08e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDFAHGHL_02605	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MDFAHGHL_02606	3.96e-64	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MDFAHGHL_02607	1.46e-15	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDFAHGHL_02610	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDFAHGHL_02611	1.91e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_02612	9.14e-203	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDFAHGHL_02613	9.34e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02614	1.18e-224	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MDFAHGHL_02615	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MDFAHGHL_02616	3.14e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02617	4.14e-176	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MDFAHGHL_02618	3.39e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MDFAHGHL_02619	2.76e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDFAHGHL_02620	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDFAHGHL_02621	3.09e-287	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDFAHGHL_02622	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDFAHGHL_02623	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MDFAHGHL_02624	2.4e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_02625	2.05e-131	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02626	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MDFAHGHL_02627	1.49e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDFAHGHL_02628	9.6e-73	-	-	-	-	-	-	-	-
MDFAHGHL_02629	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MDFAHGHL_02630	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MDFAHGHL_02631	1.79e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MDFAHGHL_02632	2.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MDFAHGHL_02634	2.21e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDFAHGHL_02635	6.12e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MDFAHGHL_02636	4.6e-272	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MDFAHGHL_02637	2.15e-195	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MDFAHGHL_02638	1.14e-175	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MDFAHGHL_02639	5.12e-242	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MDFAHGHL_02640	2.4e-169	kipR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02641	8.11e-152	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MDFAHGHL_02643	5.95e-75	yczJ	-	-	S	-	-	-	biosynthesis
MDFAHGHL_02644	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MDFAHGHL_02645	2.2e-222	ycsN	-	-	S	-	-	-	Oxidoreductase
MDFAHGHL_02646	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MDFAHGHL_02647	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MDFAHGHL_02648	7.7e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_02649	1.17e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MDFAHGHL_02650	5.11e-152	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDFAHGHL_02651	5.1e-21	ydaG	-	-	S	-	-	-	general stress protein
MDFAHGHL_02652	1.98e-31	ydaG	-	-	S	-	-	-	general stress protein
MDFAHGHL_02653	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MDFAHGHL_02654	5.59e-64	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MDFAHGHL_02655	7.97e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MDFAHGHL_02656	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDFAHGHL_02657	4.86e-259	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MDFAHGHL_02658	1.13e-190	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MDFAHGHL_02659	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MDFAHGHL_02660	4.54e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MDFAHGHL_02661	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MDFAHGHL_02663	0.0	ydaO	-	-	E	-	-	-	amino acid
MDFAHGHL_02664	2.64e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MDFAHGHL_02665	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDFAHGHL_02666	1.45e-98	-	-	-	K	-	-	-	acetyltransferase
MDFAHGHL_02668	2.1e-268	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MDFAHGHL_02670	1.09e-11	-	-	-	-	-	-	-	-
MDFAHGHL_02672	3.08e-115	-	-	-	-	-	-	-	-
MDFAHGHL_02673	9.66e-57	-	-	-	-	-	-	-	-
MDFAHGHL_02674	1.29e-54	-	-	-	-	-	-	-	-
MDFAHGHL_02675	2.28e-289	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MDFAHGHL_02677	1.95e-45	ydaT	-	-	-	-	-	-	-
MDFAHGHL_02678	1.86e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MDFAHGHL_02679	7.05e-72	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MDFAHGHL_02680	3.6e-175	ydbA	-	-	P	-	-	-	EcsC protein family
MDFAHGHL_02681	1.24e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MDFAHGHL_02682	8.99e-83	ydbB	-	-	G	-	-	-	Cupin domain
MDFAHGHL_02683	4.45e-83	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MDFAHGHL_02684	1.64e-199	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MDFAHGHL_02685	4.39e-254	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MDFAHGHL_02686	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDFAHGHL_02687	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MDFAHGHL_02688	3.91e-287	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_02689	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
MDFAHGHL_02690	1.67e-221	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_02691	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDFAHGHL_02692	9.32e-70	ydbL	-	-	-	-	-	-	-
MDFAHGHL_02693	1.16e-265	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MDFAHGHL_02694	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
MDFAHGHL_02695	6.58e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
MDFAHGHL_02696	2.84e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDFAHGHL_02697	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
MDFAHGHL_02698	1.78e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MDFAHGHL_02699	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDFAHGHL_02700	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDFAHGHL_02701	6.83e-109	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MDFAHGHL_02702	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MDFAHGHL_02703	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MDFAHGHL_02704	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDFAHGHL_02705	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MDFAHGHL_02706	8.06e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDFAHGHL_02707	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MDFAHGHL_02708	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MDFAHGHL_02709	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MDFAHGHL_02710	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MDFAHGHL_02711	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MDFAHGHL_02712	8.83e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MDFAHGHL_02713	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MDFAHGHL_02714	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MDFAHGHL_02715	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_02716	5.75e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MDFAHGHL_02717	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MDFAHGHL_02718	1.78e-21	-	-	-	-	-	-	-	-
MDFAHGHL_02719	1.22e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MDFAHGHL_02724	1.29e-122	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MDFAHGHL_02725	1.13e-193	-	-	-	S	-	-	-	Serine aminopeptidase, S33
MDFAHGHL_02726	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
MDFAHGHL_02727	1.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02728	1.09e-96	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MDFAHGHL_02729	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MDFAHGHL_02730	1.59e-85	-	-	-	S	-	-	-	YjbR
MDFAHGHL_02731	5.78e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02732	4e-147	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MDFAHGHL_02733	7.04e-133	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
MDFAHGHL_02734	2.48e-173	-	-	-	C	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_02735	9.09e-236	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDFAHGHL_02736	1.62e-227	-	-	-	C	-	-	-	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDFAHGHL_02737	6.06e-75	-	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02738	6.56e-252	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MDFAHGHL_02739	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MDFAHGHL_02740	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MDFAHGHL_02741	2.63e-53	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02742	2.38e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MDFAHGHL_02743	2.76e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
MDFAHGHL_02744	3.94e-133	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MDFAHGHL_02745	1.01e-254	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MDFAHGHL_02746	1.74e-36	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MDFAHGHL_02747	2.16e-167	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDFAHGHL_02748	2.31e-162	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MDFAHGHL_02749	1.18e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MDFAHGHL_02750	8.2e-68	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MDFAHGHL_02751	1.04e-216	ybfA	-	-	K	-	-	-	FR47-like protein
MDFAHGHL_02752	2.34e-301	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_02753	1.06e-235	-	-	-	S	-	-	-	Patatin-like phospholipase
MDFAHGHL_02754	2.49e-110	-	-	-	S	-	-	-	DinB superfamily
MDFAHGHL_02755	5.19e-85	-	-	-	G	-	-	-	Cupin domain
MDFAHGHL_02758	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MDFAHGHL_02759	2.42e-100	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02760	3.22e-217	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MDFAHGHL_02761	7.41e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MDFAHGHL_02763	1.51e-127	yrkC	-	-	G	-	-	-	Cupin domain
MDFAHGHL_02764	4.27e-114	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MDFAHGHL_02765	3.64e-191	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MDFAHGHL_02767	2.49e-255	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MDFAHGHL_02768	3.17e-75	ydeH	-	-	-	-	-	-	-
MDFAHGHL_02769	2.61e-110	-	-	-	F	-	-	-	nucleoside 2-deoxyribosyltransferase
MDFAHGHL_02770	1.01e-138	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDFAHGHL_02771	1.05e-74	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDFAHGHL_02772	9.13e-191	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MDFAHGHL_02773	1.1e-192	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDFAHGHL_02774	1.69e-298	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MDFAHGHL_02775	6.74e-218	-	-	-	S	-	-	-	Sodium Bile acid symporter family
MDFAHGHL_02776	6.37e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MDFAHGHL_02777	1.47e-86	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MDFAHGHL_02778	2.42e-282	nhaC_1	-	-	C	-	-	-	antiporter
MDFAHGHL_02779	2.79e-161	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MDFAHGHL_02780	6.37e-131	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MDFAHGHL_02781	1.46e-146	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_02783	7.21e-136	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
MDFAHGHL_02784	3.03e-159	-	-	-	T	-	-	-	Transcriptional regulator
MDFAHGHL_02785	1.08e-244	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MDFAHGHL_02786	8.65e-136	-	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_02787	1.59e-252	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MDFAHGHL_02788	1.2e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02789	3.17e-203	ydeK	-	-	EG	-	-	-	-transporter
MDFAHGHL_02790	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDFAHGHL_02791	4.9e-64	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MDFAHGHL_02792	2.4e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
MDFAHGHL_02793	5.61e-84	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDFAHGHL_02794	8.58e-180	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDFAHGHL_02795	2.86e-85	yraF	-	-	M	-	-	-	Spore coat protein
MDFAHGHL_02796	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
MDFAHGHL_02797	5.37e-279	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_02798	1.39e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_02799	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MDFAHGHL_02800	3.47e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MDFAHGHL_02801	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MDFAHGHL_02802	2.72e-129	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_02803	2.47e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_02804	6.54e-251	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MDFAHGHL_02805	3.9e-268	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MDFAHGHL_02806	1.31e-286	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDFAHGHL_02807	1.06e-198	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDFAHGHL_02808	9e-158	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDFAHGHL_02809	3.44e-105	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MDFAHGHL_02810	7.18e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MDFAHGHL_02811	8.93e-192	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDFAHGHL_02812	1.58e-145	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MDFAHGHL_02813	7.76e-187	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MDFAHGHL_02814	6.38e-197	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MDFAHGHL_02815	6.99e-28	-	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MDFAHGHL_02816	2.79e-155	ydhC	-	-	K	-	-	-	FCD
MDFAHGHL_02817	4.77e-291	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDFAHGHL_02820	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MDFAHGHL_02822	4.3e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MDFAHGHL_02823	1.11e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MDFAHGHL_02824	7.17e-172	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MDFAHGHL_02825	3.25e-154	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MDFAHGHL_02826	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MDFAHGHL_02827	4.25e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MDFAHGHL_02828	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MDFAHGHL_02829	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02830	0.0	ybeC	-	-	E	-	-	-	amino acid
MDFAHGHL_02831	5.67e-195	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MDFAHGHL_02832	2.41e-111	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MDFAHGHL_02833	8.11e-237	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MDFAHGHL_02834	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDFAHGHL_02837	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_02840	1.77e-236	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MDFAHGHL_02841	2.59e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MDFAHGHL_02842	1.02e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MDFAHGHL_02843	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MDFAHGHL_02844	7.23e-162	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDFAHGHL_02845	1.63e-68	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDFAHGHL_02846	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MDFAHGHL_02847	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MDFAHGHL_02848	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDFAHGHL_02849	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDFAHGHL_02850	8.18e-163	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDFAHGHL_02851	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MDFAHGHL_02852	4.09e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDFAHGHL_02853	3.45e-29	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDFAHGHL_02854	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDFAHGHL_02855	5.82e-30	-	-	-	-	-	-	-	-
MDFAHGHL_02856	7.93e-101	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
MDFAHGHL_02857	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MDFAHGHL_02858	7.16e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MDFAHGHL_02859	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MDFAHGHL_02860	4.24e-221	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MDFAHGHL_02861	5.75e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MDFAHGHL_02862	1.17e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MDFAHGHL_02863	1.84e-201	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDFAHGHL_02864	3.88e-163	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MDFAHGHL_02865	4.68e-216	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MDFAHGHL_02866	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MDFAHGHL_02867	1.68e-194	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MDFAHGHL_02868	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_02869	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MDFAHGHL_02870	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
MDFAHGHL_02871	2.12e-196	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MDFAHGHL_02873	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MDFAHGHL_02874	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MDFAHGHL_02875	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MDFAHGHL_02876	1.24e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDFAHGHL_02877	6.84e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MDFAHGHL_02878	9.37e-276	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MDFAHGHL_02879	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MDFAHGHL_02880	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MDFAHGHL_02881	8.06e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_02882	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MDFAHGHL_02883	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDFAHGHL_02884	2.94e-166	yebC	-	-	M	-	-	-	Membrane
MDFAHGHL_02886	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MDFAHGHL_02887	1.82e-37	yebG	-	-	S	-	-	-	NETI protein
MDFAHGHL_02888	4.6e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDFAHGHL_02889	1.31e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDFAHGHL_02890	6.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDFAHGHL_02891	3.53e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MDFAHGHL_02892	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDFAHGHL_02893	2.32e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDFAHGHL_02894	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDFAHGHL_02895	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDFAHGHL_02896	2.17e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MDFAHGHL_02897	4.22e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDFAHGHL_02898	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MDFAHGHL_02899	2.42e-299	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MDFAHGHL_02900	5.93e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MDFAHGHL_02901	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MDFAHGHL_02902	7.32e-248	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MDFAHGHL_02903	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02904	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MDFAHGHL_02905	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MDFAHGHL_02906	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MDFAHGHL_02907	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDFAHGHL_02908	2.74e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MDFAHGHL_02909	4.42e-249	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MDFAHGHL_02910	1.44e-158	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MDFAHGHL_02911	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDFAHGHL_02912	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDFAHGHL_02913	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDFAHGHL_02914	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDFAHGHL_02915	9.46e-199	yerO	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_02916	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MDFAHGHL_02917	5.16e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDFAHGHL_02918	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDFAHGHL_02920	7.9e-202	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MDFAHGHL_02921	3.92e-175	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MDFAHGHL_02922	6.2e-103	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MDFAHGHL_02923	4.77e-106	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MDFAHGHL_02924	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MDFAHGHL_02925	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MDFAHGHL_02927	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MDFAHGHL_02928	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MDFAHGHL_02929	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MDFAHGHL_02930	1.29e-128	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MDFAHGHL_02931	5.92e-05	-	-	-	-	-	-	-	-
MDFAHGHL_02932	8.99e-157	yetF	-	-	S	-	-	-	membrane
MDFAHGHL_02933	5.49e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MDFAHGHL_02934	1.32e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDFAHGHL_02935	1.88e-198	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDFAHGHL_02936	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MDFAHGHL_02937	1.82e-73	-	-	-	H	-	-	-	riboflavin kinase activity
MDFAHGHL_02938	1.54e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDFAHGHL_02939	2.08e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_02940	1.41e-263	yetM	-	-	CH	-	-	-	FAD binding domain
MDFAHGHL_02941	2.38e-252	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MDFAHGHL_02942	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MDFAHGHL_02944	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MDFAHGHL_02945	8.77e-190	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MDFAHGHL_02946	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MDFAHGHL_02947	2.81e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MDFAHGHL_02948	1.78e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MDFAHGHL_02949	2.95e-240	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MDFAHGHL_02950	2.7e-278	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_02951	2.06e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MDFAHGHL_02952	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDFAHGHL_02953	2.85e-169	yfmS	-	-	NT	-	-	-	chemotaxis protein
MDFAHGHL_02954	2.1e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_02955	4.2e-266	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDFAHGHL_02956	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDFAHGHL_02957	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MDFAHGHL_02958	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MDFAHGHL_02959	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDFAHGHL_02960	1.78e-264	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MDFAHGHL_02961	7.93e-64	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MDFAHGHL_02962	5.73e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MDFAHGHL_02963	4.44e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MDFAHGHL_02964	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MDFAHGHL_02965	8.27e-311	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MDFAHGHL_02966	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDFAHGHL_02969	6.63e-56	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
MDFAHGHL_02970	3.17e-100	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
MDFAHGHL_02971	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MDFAHGHL_02972	1.14e-153	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDFAHGHL_02973	8.33e-228	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MDFAHGHL_02974	2.01e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MDFAHGHL_02975	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MDFAHGHL_02976	1.49e-279	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MDFAHGHL_02977	3.36e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MDFAHGHL_02978	5.28e-160	yflK	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_02979	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MDFAHGHL_02980	1.98e-26	yflI	-	-	-	-	-	-	-
MDFAHGHL_02981	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MDFAHGHL_02982	2.11e-154	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MDFAHGHL_02983	8.77e-315	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MDFAHGHL_02984	7.03e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MDFAHGHL_02985	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MDFAHGHL_02986	8.46e-84	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MDFAHGHL_02987	8.64e-106	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MDFAHGHL_02988	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MDFAHGHL_02989	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MDFAHGHL_02990	2.71e-314	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_02991	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MDFAHGHL_02992	2.38e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MDFAHGHL_02993	1.45e-158	frp	-	-	C	-	-	-	nitroreductase
MDFAHGHL_02994	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
MDFAHGHL_02995	7.7e-256	yibE	-	-	S	-	-	-	YibE/F-like protein
MDFAHGHL_02996	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MDFAHGHL_02997	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MDFAHGHL_02998	6.94e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDFAHGHL_02999	3.54e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDFAHGHL_03000	1.82e-177	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MDFAHGHL_03001	6.98e-252	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03002	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MDFAHGHL_03003	1.69e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDFAHGHL_03004	5.26e-70	yfkI	-	-	S	-	-	-	gas vesicle protein
MDFAHGHL_03005	1.34e-77	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDFAHGHL_03006	1.44e-92	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDFAHGHL_03007	6.71e-12	-	-	-	-	-	-	-	-
MDFAHGHL_03008	9.79e-279	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03009	8.42e-239	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MDFAHGHL_03010	5.66e-186	yfkD	-	-	S	-	-	-	YfkD-like protein
MDFAHGHL_03011	8.63e-188	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MDFAHGHL_03012	2.06e-282	yfkA	-	-	S	-	-	-	YfkB-like domain
MDFAHGHL_03013	7.99e-37	yfjT	-	-	-	-	-	-	-
MDFAHGHL_03014	4.36e-199	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MDFAHGHL_03015	4.82e-194	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MDFAHGHL_03017	2.24e-236	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MDFAHGHL_03018	1.04e-209	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDFAHGHL_03019	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDFAHGHL_03020	2.15e-67	-	-	-	S	-	-	-	YfzA-like protein
MDFAHGHL_03021	1.21e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDFAHGHL_03022	5.79e-122	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MDFAHGHL_03023	5.55e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDFAHGHL_03024	3.74e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDFAHGHL_03025	2.91e-276	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDFAHGHL_03026	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDFAHGHL_03027	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MDFAHGHL_03028	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MDFAHGHL_03029	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDFAHGHL_03030	7.72e-179	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MDFAHGHL_03031	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_03032	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MDFAHGHL_03033	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDFAHGHL_03034	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDFAHGHL_03035	5.54e-82	yfiD3	-	-	S	-	-	-	DoxX
MDFAHGHL_03036	3.46e-207	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MDFAHGHL_03037	6.5e-218	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDFAHGHL_03038	1.61e-125	padR	-	-	K	-	-	-	transcriptional
MDFAHGHL_03039	3.61e-144	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDFAHGHL_03040	8.4e-240	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MDFAHGHL_03042	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MDFAHGHL_03043	2.87e-61	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MDFAHGHL_03044	1.14e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MDFAHGHL_03045	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MDFAHGHL_03046	1.38e-108	yfiV	-	-	K	-	-	-	transcriptional
MDFAHGHL_03047	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDFAHGHL_03048	2.75e-213	yfhB	-	-	S	-	-	-	PhzF family
MDFAHGHL_03049	8.22e-138	yfhC	-	-	C	-	-	-	nitroreductase
MDFAHGHL_03050	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
MDFAHGHL_03052	1.66e-183	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MDFAHGHL_03053	7.27e-19	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MDFAHGHL_03054	1.82e-182	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MDFAHGHL_03055	1.23e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MDFAHGHL_03056	2.86e-268	yfhI	-	-	EGP	-	-	-	-transporter
MDFAHGHL_03058	8.56e-217	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MDFAHGHL_03059	3.12e-60	yfhJ	-	-	S	-	-	-	WVELL protein
MDFAHGHL_03060	6.14e-105	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MDFAHGHL_03061	7.04e-56	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MDFAHGHL_03062	3.93e-218	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MDFAHGHL_03063	6.93e-212	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDFAHGHL_03064	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MDFAHGHL_03065	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MDFAHGHL_03066	8.97e-217	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MDFAHGHL_03067	2.54e-50	yfhS	-	-	-	-	-	-	-
MDFAHGHL_03068	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_03069	2.38e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MDFAHGHL_03070	4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MDFAHGHL_03071	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MDFAHGHL_03072	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MDFAHGHL_03073	9.11e-240	ygaE	-	-	S	-	-	-	Membrane
MDFAHGHL_03074	6.86e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MDFAHGHL_03075	3.41e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MDFAHGHL_03076	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MDFAHGHL_03077	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MDFAHGHL_03078	2.75e-213	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MDFAHGHL_03079	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MDFAHGHL_03096	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
MDFAHGHL_03097	2.07e-173	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MDFAHGHL_03098	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDFAHGHL_03099	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MDFAHGHL_03102	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MDFAHGHL_03103	5.69e-235	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MDFAHGHL_03104	4.5e-180	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MDFAHGHL_03105	3.03e-230	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MDFAHGHL_03106	6.07e-188	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MDFAHGHL_03107	1.81e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MDFAHGHL_03108	1.18e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDFAHGHL_03109	3.16e-107	ygaO	-	-	-	-	-	-	-
MDFAHGHL_03110	9.41e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03112	2.24e-146	yhzB	-	-	S	-	-	-	B3/4 domain
MDFAHGHL_03113	5.95e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MDFAHGHL_03114	6.09e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
MDFAHGHL_03115	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDFAHGHL_03116	1.39e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MDFAHGHL_03117	6.95e-86	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MDFAHGHL_03118	8.18e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MDFAHGHL_03119	1.23e-07	-	-	-	-	-	-	-	-
MDFAHGHL_03120	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MDFAHGHL_03121	4.34e-281	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MDFAHGHL_03122	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MDFAHGHL_03123	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MDFAHGHL_03124	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MDFAHGHL_03125	5.26e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDFAHGHL_03126	1.41e-72	yhcC	-	-	-	-	-	-	-
MDFAHGHL_03127	1.65e-66	-	-	-	-	-	-	-	-
MDFAHGHL_03128	1.64e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03129	2.08e-161	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_03130	2.35e-215	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_03131	1.91e-210	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDFAHGHL_03132	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MDFAHGHL_03133	4.13e-190	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDFAHGHL_03134	9.23e-247	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MDFAHGHL_03135	5.49e-295	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_03136	8.1e-81	yhcM	-	-	-	-	-	-	-
MDFAHGHL_03137	5.43e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDFAHGHL_03138	1.42e-208	yhcP	-	-	-	-	-	-	-
MDFAHGHL_03139	1.74e-150	yhcQ	-	-	M	-	-	-	Spore coat protein
MDFAHGHL_03140	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MDFAHGHL_03141	8.19e-140	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MDFAHGHL_03142	2.88e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDFAHGHL_03143	1.88e-92	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MDFAHGHL_03144	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MDFAHGHL_03145	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MDFAHGHL_03146	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDFAHGHL_03147	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDFAHGHL_03148	1.04e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MDFAHGHL_03149	3.3e-198	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDFAHGHL_03150	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDFAHGHL_03151	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MDFAHGHL_03152	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MDFAHGHL_03153	7.43e-260	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_03154	3.15e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDFAHGHL_03155	8.03e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MDFAHGHL_03156	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
MDFAHGHL_03157	2.42e-70	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MDFAHGHL_03158	1.27e-298	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDFAHGHL_03159	3.25e-97	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MDFAHGHL_03160	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
MDFAHGHL_03161	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MDFAHGHL_03162	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MDFAHGHL_03163	6.44e-177	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MDFAHGHL_03164	8.17e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03165	2.33e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MDFAHGHL_03166	7.83e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_03167	8.9e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MDFAHGHL_03168	1.78e-268	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDFAHGHL_03169	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MDFAHGHL_03170	1.69e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MDFAHGHL_03171	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_03172	1.59e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDFAHGHL_03173	3.94e-307	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDFAHGHL_03174	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MDFAHGHL_03175	6e-288	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MDFAHGHL_03176	3.87e-301	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDFAHGHL_03177	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MDFAHGHL_03178	2.12e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDFAHGHL_03179	4.97e-79	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDFAHGHL_03180	1.28e-165	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MDFAHGHL_03181	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MDFAHGHL_03182	1.11e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MDFAHGHL_03183	7.18e-181	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MDFAHGHL_03184	4.89e-201	nodB1	-	-	G	-	-	-	deacetylase
MDFAHGHL_03185	1.19e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MDFAHGHL_03186	1.22e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03187	2.29e-125	ymcC	-	-	S	-	-	-	Membrane
MDFAHGHL_03188	2.49e-110	-	-	-	T	-	-	-	universal stress protein
MDFAHGHL_03190	4.92e-140	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDFAHGHL_03191	8.91e-251	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDFAHGHL_03192	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MDFAHGHL_03193	1.04e-68	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MDFAHGHL_03195	1.15e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MDFAHGHL_03196	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MDFAHGHL_03197	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MDFAHGHL_03198	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MDFAHGHL_03199	3.88e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MDFAHGHL_03200	2.32e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MDFAHGHL_03201	5.21e-260	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MDFAHGHL_03202	1.03e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDFAHGHL_03203	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MDFAHGHL_03204	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MDFAHGHL_03205	5.95e-208	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MDFAHGHL_03206	4.58e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MDFAHGHL_03208	4.11e-175	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MDFAHGHL_03209	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
MDFAHGHL_03210	3.92e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_03211	7.16e-279	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MDFAHGHL_03212	1.57e-301	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MDFAHGHL_03213	0.0	yhaN	-	-	L	-	-	-	AAA domain
MDFAHGHL_03214	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MDFAHGHL_03215	3.48e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MDFAHGHL_03216	5.57e-187	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDFAHGHL_03217	6.43e-41	-	-	-	-	-	-	-	-
MDFAHGHL_03218	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MDFAHGHL_03219	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MDFAHGHL_03220	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MDFAHGHL_03221	4.74e-55	yhaH	-	-	S	-	-	-	YtxH-like protein
MDFAHGHL_03222	2.55e-24	-	-	-	-	-	-	-	-
MDFAHGHL_03223	4.09e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MDFAHGHL_03224	2.14e-104	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDFAHGHL_03225	4.96e-134	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDFAHGHL_03226	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MDFAHGHL_03227	1.5e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MDFAHGHL_03228	5.74e-17	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDFAHGHL_03229	4.1e-231	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDFAHGHL_03230	2.48e-161	ecsC	-	-	S	-	-	-	EcsC protein family
MDFAHGHL_03231	5.33e-287	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MDFAHGHL_03232	4.16e-313	yhfA	-	-	C	-	-	-	membrane
MDFAHGHL_03233	1.93e-58	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MDFAHGHL_03234	1.05e-152	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDFAHGHL_03235	2.98e-300	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDFAHGHL_03236	2.2e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MDFAHGHL_03237	7.76e-233	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MDFAHGHL_03238	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MDFAHGHL_03239	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03240	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MDFAHGHL_03241	5.92e-235	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDFAHGHL_03243	1.81e-251	yhfE	-	-	G	-	-	-	peptidase M42
MDFAHGHL_03244	3.36e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDFAHGHL_03246	1.7e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MDFAHGHL_03247	1.85e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MDFAHGHL_03248	2.21e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
MDFAHGHL_03249	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MDFAHGHL_03250	2.38e-86	yhfM	-	-	-	-	-	-	-
MDFAHGHL_03251	7.06e-118	yhfN	-	-	O	-	-	-	Peptidase M48
MDFAHGHL_03252	6.93e-149	yhfN	-	-	O	-	-	-	Peptidase M48
MDFAHGHL_03253	4.14e-94	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDFAHGHL_03254	3.1e-99	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDFAHGHL_03255	1.83e-201	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MDFAHGHL_03256	1.48e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MDFAHGHL_03257	2.59e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MDFAHGHL_03258	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MDFAHGHL_03259	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MDFAHGHL_03260	1.61e-276	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MDFAHGHL_03261	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MDFAHGHL_03262	1.35e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_03263	5.7e-44	yhzC	-	-	S	-	-	-	IDEAL
MDFAHGHL_03264	7.64e-142	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MDFAHGHL_03265	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MDFAHGHL_03266	2.25e-73	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MDFAHGHL_03267	3.6e-122	-	-	-	S	-	-	-	MepB protein
MDFAHGHL_03268	8e-166	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MDFAHGHL_03269	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MDFAHGHL_03270	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
MDFAHGHL_03271	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDFAHGHL_03272	1.37e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MDFAHGHL_03273	4.12e-79	yhjD	-	-	-	-	-	-	-
MDFAHGHL_03274	1.64e-144	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MDFAHGHL_03275	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDFAHGHL_03276	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MDFAHGHL_03277	1.03e-123	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_03278	8.45e-263	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MDFAHGHL_03279	4.57e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03280	2.72e-142	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MDFAHGHL_03281	4.92e-120	yhjR	-	-	S	-	-	-	Rubrerythrin
MDFAHGHL_03282	2.11e-161	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDFAHGHL_03283	7.65e-129	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MDFAHGHL_03284	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MDFAHGHL_03285	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MDFAHGHL_03286	1.11e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDFAHGHL_03287	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MDFAHGHL_03288	2.64e-67	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MDFAHGHL_03289	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MDFAHGHL_03290	1.67e-86	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MDFAHGHL_03291	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MDFAHGHL_03292	8.51e-109	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MDFAHGHL_03293	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MDFAHGHL_03294	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MDFAHGHL_03295	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MDFAHGHL_03296	1.54e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MDFAHGHL_03297	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
MDFAHGHL_03298	1.12e-125	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MDFAHGHL_03299	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDFAHGHL_03300	9.75e-174	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MDFAHGHL_03301	9.14e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
MDFAHGHL_03302	6.71e-206	yisR	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03303	3.11e-116	yisT	-	-	S	-	-	-	DinB family
MDFAHGHL_03304	8.48e-96	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MDFAHGHL_03305	2.38e-239	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDFAHGHL_03306	2.87e-113	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MDFAHGHL_03307	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDFAHGHL_03308	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MDFAHGHL_03309	6.39e-79	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MDFAHGHL_03310	1.59e-206	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MDFAHGHL_03311	6.25e-221	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
MDFAHGHL_03312	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MDFAHGHL_03313	6.52e-310	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MDFAHGHL_03315	3.18e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03316	1.61e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MDFAHGHL_03317	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MDFAHGHL_03318	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MDFAHGHL_03319	1.49e-11	-	-	-	-	-	-	-	-
MDFAHGHL_03320	1.52e-198	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MDFAHGHL_03321	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MDFAHGHL_03322	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MDFAHGHL_03323	2.87e-106	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MDFAHGHL_03324	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MDFAHGHL_03325	1.18e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MDFAHGHL_03326	1.18e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDFAHGHL_03327	5.39e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDFAHGHL_03328	5.17e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MDFAHGHL_03329	1.97e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MDFAHGHL_03330	1.69e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDFAHGHL_03331	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MDFAHGHL_03332	3.02e-227	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDFAHGHL_03333	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MDFAHGHL_03334	5.24e-33	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MDFAHGHL_03335	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MDFAHGHL_03336	2.12e-137	yjaV	-	-	-	-	-	-	-
MDFAHGHL_03337	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MDFAHGHL_03338	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MDFAHGHL_03339	2.82e-44	yjzB	-	-	-	-	-	-	-
MDFAHGHL_03340	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDFAHGHL_03341	2.71e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDFAHGHL_03342	7.48e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MDFAHGHL_03343	4.15e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03344	6.88e-206	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03345	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MDFAHGHL_03346	4.24e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03347	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03348	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MDFAHGHL_03349	3.18e-85	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MDFAHGHL_03350	1.84e-126	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MDFAHGHL_03351	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDFAHGHL_03352	2.53e-213	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03353	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03354	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03355	2.19e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03356	5.82e-289	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MDFAHGHL_03357	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDFAHGHL_03358	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDFAHGHL_03359	6.8e-142	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MDFAHGHL_03360	8.03e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDFAHGHL_03361	8.44e-284	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MDFAHGHL_03362	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MDFAHGHL_03363	3.14e-27	-	-	-	-	-	-	-	-
MDFAHGHL_03364	6.05e-220	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MDFAHGHL_03365	1.22e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MDFAHGHL_03366	7.66e-153	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDFAHGHL_03367	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03368	3.5e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MDFAHGHL_03369	1.56e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MDFAHGHL_03370	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDFAHGHL_03371	2.35e-211	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDFAHGHL_03372	1.51e-183	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MDFAHGHL_03373	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDFAHGHL_03374	4.88e-178	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MDFAHGHL_03375	8.09e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MDFAHGHL_03376	6.85e-279	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MDFAHGHL_03377	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
MDFAHGHL_03378	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDFAHGHL_03379	8.18e-243	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDFAHGHL_03380	1.83e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDFAHGHL_03381	1.68e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MDFAHGHL_03382	2.9e-126	yjbX	-	-	S	-	-	-	Spore coat protein
MDFAHGHL_03383	2.1e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MDFAHGHL_03384	4.28e-121	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MDFAHGHL_03385	7.48e-100	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MDFAHGHL_03386	8.38e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
MDFAHGHL_03387	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MDFAHGHL_03388	1.69e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MDFAHGHL_03390	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDFAHGHL_03391	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MDFAHGHL_03392	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDFAHGHL_03393	1.49e-49	-	-	-	-	-	-	-	-
MDFAHGHL_03394	1.29e-184	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MDFAHGHL_03395	3.23e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MDFAHGHL_03396	2.04e-170	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MDFAHGHL_03397	4.32e-48	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MDFAHGHL_03398	3.66e-98	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDFAHGHL_03399	2.43e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MDFAHGHL_03400	8.27e-163	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MDFAHGHL_03401	3.37e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDFAHGHL_03402	1.15e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDFAHGHL_03404	3.91e-06	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MDFAHGHL_03405	2.11e-75	-	-	-	-	-	-	-	-
MDFAHGHL_03406	2.84e-74	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MDFAHGHL_03407	1.96e-121	-	-	-	-	-	-	-	-
MDFAHGHL_03410	4.69e-174	-	-	-	-	-	-	-	-
MDFAHGHL_03412	1.45e-14	-	-	-	-	-	-	-	-
MDFAHGHL_03415	1.32e-62	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MDFAHGHL_03416	7.55e-12	-	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03421	1.72e-212	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MDFAHGHL_03422	1.27e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MDFAHGHL_03423	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MDFAHGHL_03424	1.44e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_03425	3.28e-282	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MDFAHGHL_03426	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDFAHGHL_03427	2.85e-237	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDFAHGHL_03428	2.81e-279	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDFAHGHL_03429	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDFAHGHL_03430	3.63e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_03431	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDFAHGHL_03432	5.65e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MDFAHGHL_03433	1.02e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MDFAHGHL_03434	2.03e-190	-	-	-	N	-	-	-	Kelch motif
MDFAHGHL_03437	1.18e-134	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MDFAHGHL_03439	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
MDFAHGHL_03440	1.08e-92	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MDFAHGHL_03441	1.13e-122	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MDFAHGHL_03442	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MDFAHGHL_03443	1.05e-115	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDFAHGHL_03444	2.28e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDFAHGHL_03445	2.08e-286	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDFAHGHL_03446	1.73e-40	-	-	-	-	-	-	-	-
MDFAHGHL_03447	4.78e-186	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MDFAHGHL_03448	3.55e-159	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MDFAHGHL_03449	5.56e-169	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03450	8.66e-229	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MDFAHGHL_03451	8.91e-121	yjlB	-	-	S	-	-	-	Cupin domain
MDFAHGHL_03452	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MDFAHGHL_03453	7.49e-281	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDFAHGHL_03454	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MDFAHGHL_03455	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MDFAHGHL_03456	7.19e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MDFAHGHL_03457	2.08e-44	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MDFAHGHL_03458	7.91e-297	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MDFAHGHL_03459	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MDFAHGHL_03460	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDFAHGHL_03461	4.32e-105	yjoA	-	-	S	-	-	-	DinB family
MDFAHGHL_03462	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MDFAHGHL_03464	1.17e-221	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MDFAHGHL_03465	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
MDFAHGHL_03466	7.87e-144	yjqB	-	-	S	-	-	-	phage-related replication protein
MDFAHGHL_03467	1.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MDFAHGHL_03468	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDFAHGHL_03470	1.46e-194	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MDFAHGHL_03474	3.05e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MDFAHGHL_03475	3.38e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MDFAHGHL_03476	3.37e-156	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MDFAHGHL_03477	5.17e-304	xkdE3	-	-	S	-	-	-	portal protein
MDFAHGHL_03478	1.19e-44	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MDFAHGHL_03479	1.02e-52	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MDFAHGHL_03480	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
MDFAHGHL_03481	2.17e-61	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MDFAHGHL_03482	1.42e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MDFAHGHL_03483	1.2e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MDFAHGHL_03484	4.28e-74	xkdJ	-	-	-	-	-	-	-
MDFAHGHL_03485	1.57e-20	-	-	-	-	-	-	-	-
MDFAHGHL_03486	1.33e-286	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MDFAHGHL_03487	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MDFAHGHL_03488	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MDFAHGHL_03489	4.33e-27	-	-	-	-	-	-	-	-
MDFAHGHL_03490	4.06e-278	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MDFAHGHL_03491	5.39e-144	xkdP	-	-	S	-	-	-	Lysin motif
MDFAHGHL_03492	1.87e-206	xkdQ	-	-	G	-	-	-	NLP P60 protein
MDFAHGHL_03493	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MDFAHGHL_03494	1.16e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MDFAHGHL_03495	6.22e-212	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDFAHGHL_03496	1.43e-112	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MDFAHGHL_03497	2.56e-37	-	-	-	-	-	-	-	-
MDFAHGHL_03498	2.44e-83	-	-	-	-	-	-	-	-
MDFAHGHL_03500	5.6e-41	xkdX	-	-	-	-	-	-	-
MDFAHGHL_03501	2.46e-68	xepA	-	-	-	-	-	-	-
MDFAHGHL_03502	5.15e-69	xepA	-	-	-	-	-	-	-
MDFAHGHL_03503	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MDFAHGHL_03504	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MDFAHGHL_03505	3.49e-215	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MDFAHGHL_03506	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MDFAHGHL_03507	3.13e-171	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MDFAHGHL_03508	8.61e-227	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MDFAHGHL_03509	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MDFAHGHL_03510	1.31e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MDFAHGHL_03511	3.43e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MDFAHGHL_03512	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDFAHGHL_03513	1.34e-230	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MDFAHGHL_03514	1.55e-72	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
MDFAHGHL_03516	5.55e-278	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDFAHGHL_03517	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MDFAHGHL_03519	3.24e-106	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MDFAHGHL_03520	1.2e-66	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MDFAHGHL_03521	2.4e-205	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03522	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDFAHGHL_03523	1.12e-243	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03524	7.58e-25	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDFAHGHL_03525	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MDFAHGHL_03526	3.4e-227	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MDFAHGHL_03527	1.34e-258	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MDFAHGHL_03528	1.18e-221	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDFAHGHL_03529	2.31e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDFAHGHL_03530	1.46e-263	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MDFAHGHL_03531	1.46e-204	ykgA	-	-	E	-	-	-	Amidinotransferase
MDFAHGHL_03532	1.25e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MDFAHGHL_03533	3.83e-132	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDFAHGHL_03534	2.02e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MDFAHGHL_03535	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MDFAHGHL_03536	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MDFAHGHL_03537	4.35e-262	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDFAHGHL_03538	1.37e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDFAHGHL_03539	3.46e-58	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MDFAHGHL_03540	1.2e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MDFAHGHL_03541	1.92e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MDFAHGHL_03542	6.79e-78	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDFAHGHL_03544	2.58e-277	-	-	-	M	-	-	-	Glycosyl transferase family 2
MDFAHGHL_03545	3.23e-187	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
MDFAHGHL_03546	3.41e-278	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03547	5.48e-156	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MDFAHGHL_03548	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDFAHGHL_03549	9e-227	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDFAHGHL_03550	8.04e-193	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDFAHGHL_03551	6.53e-171	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MDFAHGHL_03552	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_03553	4.86e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MDFAHGHL_03554	4.42e-310	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MDFAHGHL_03556	8.66e-310	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MDFAHGHL_03557	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
MDFAHGHL_03558	1.58e-23	-	-	-	-	-	-	-	-
MDFAHGHL_03559	5.25e-37	ykoL	-	-	-	-	-	-	-
MDFAHGHL_03560	1.98e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MDFAHGHL_03561	3.03e-29	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MDFAHGHL_03562	1.76e-66	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MDFAHGHL_03563	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MDFAHGHL_03564	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MDFAHGHL_03565	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
MDFAHGHL_03566	1.44e-173	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MDFAHGHL_03567	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_03568	1.69e-165	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MDFAHGHL_03569	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MDFAHGHL_03570	6.86e-163	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MDFAHGHL_03571	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MDFAHGHL_03572	4.63e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MDFAHGHL_03573	4.44e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDFAHGHL_03574	4.95e-246	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MDFAHGHL_03575	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_03576	1.94e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDFAHGHL_03578	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MDFAHGHL_03579	1.04e-288	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MDFAHGHL_03580	1.35e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDFAHGHL_03581	1.54e-292	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDFAHGHL_03582	1.58e-288	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MDFAHGHL_03583	1.4e-176	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MDFAHGHL_03584	4.52e-147	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MDFAHGHL_03585	2.6e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MDFAHGHL_03587	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MDFAHGHL_03588	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MDFAHGHL_03589	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MDFAHGHL_03590	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MDFAHGHL_03591	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MDFAHGHL_03592	7.69e-232	ykvI	-	-	S	-	-	-	membrane
MDFAHGHL_03593	7.88e-98	-	-	-	-	-	-	-	-
MDFAHGHL_03594	3.38e-138	-	-	-	-	-	-	-	-
MDFAHGHL_03595	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MDFAHGHL_03596	2.55e-102	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MDFAHGHL_03597	2.11e-131	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MDFAHGHL_03598	2.46e-122	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MDFAHGHL_03600	1.79e-77	ykvN	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03601	1.89e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MDFAHGHL_03602	2.4e-27	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MDFAHGHL_03603	2.54e-60	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MDFAHGHL_03604	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03605	7.17e-39	-	-	-	-	-	-	-	-
MDFAHGHL_03606	1.77e-143	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MDFAHGHL_03607	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDFAHGHL_03608	1.63e-101	stoA	-	-	CO	-	-	-	thiol-disulfide
MDFAHGHL_03609	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MDFAHGHL_03610	9.91e-265	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MDFAHGHL_03612	5.14e-220	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03613	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MDFAHGHL_03614	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDFAHGHL_03615	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MDFAHGHL_03616	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDFAHGHL_03617	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03618	3.53e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MDFAHGHL_03619	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MDFAHGHL_03620	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MDFAHGHL_03621	6.91e-167	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MDFAHGHL_03622	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDFAHGHL_03623	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDFAHGHL_03624	6.26e-172	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDFAHGHL_03625	2.37e-85	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDFAHGHL_03626	6.38e-15	-	-	-	-	-	-	-	-
MDFAHGHL_03627	4.75e-214	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MDFAHGHL_03628	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
MDFAHGHL_03629	7.96e-309	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03630	8.88e-117	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03631	4.65e-200	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MDFAHGHL_03632	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDFAHGHL_03633	7.72e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MDFAHGHL_03634	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03635	1.52e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MDFAHGHL_03636	4.54e-37	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MDFAHGHL_03637	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
MDFAHGHL_03638	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
MDFAHGHL_03639	1.83e-116	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDFAHGHL_03640	2.47e-222	ykuO	-	-	-	-	-	-	-
MDFAHGHL_03641	9.16e-105	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDFAHGHL_03642	2.49e-130	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDFAHGHL_03643	2.39e-277	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDFAHGHL_03644	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MDFAHGHL_03645	1.54e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MDFAHGHL_03646	8.45e-106	ykuV	-	-	CO	-	-	-	thiol-disulfide
MDFAHGHL_03647	7.46e-127	rok	-	-	K	-	-	-	Repressor of ComK
MDFAHGHL_03648	2.53e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
MDFAHGHL_03649	2.01e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDFAHGHL_03650	4.91e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDFAHGHL_03651	1.95e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MDFAHGHL_03652	3.21e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MDFAHGHL_03653	3.41e-107	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MDFAHGHL_03654	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MDFAHGHL_03655	2.2e-138	yknW	-	-	S	-	-	-	Yip1 domain
MDFAHGHL_03656	2e-246	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDFAHGHL_03657	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDFAHGHL_03658	2.45e-268	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MDFAHGHL_03659	1.18e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03660	4.75e-214	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MDFAHGHL_03661	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MDFAHGHL_03662	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MDFAHGHL_03663	1.82e-50	ykoA	-	-	-	-	-	-	-
MDFAHGHL_03664	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDFAHGHL_03665	2.54e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDFAHGHL_03666	9.85e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MDFAHGHL_03667	5.24e-17	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MDFAHGHL_03668	3.72e-235	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MDFAHGHL_03669	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MDFAHGHL_03670	5.87e-313	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MDFAHGHL_03671	1.29e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MDFAHGHL_03672	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MDFAHGHL_03673	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MDFAHGHL_03674	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDFAHGHL_03675	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MDFAHGHL_03676	7.48e-188	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MDFAHGHL_03677	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDFAHGHL_03678	1.08e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MDFAHGHL_03679	1.8e-134	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MDFAHGHL_03680	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_03681	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03682	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03683	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03684	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03685	1.32e-135	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03686	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03687	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03688	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03689	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03690	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03691	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MDFAHGHL_03692	3.48e-269	-	-	-	V	-	-	-	Beta-lactamase
MDFAHGHL_03693	1.62e-208	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDFAHGHL_03694	1.9e-22	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDFAHGHL_03695	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDFAHGHL_03696	2.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDFAHGHL_03697	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDFAHGHL_03698	5.4e-56	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MDFAHGHL_03699	4.87e-193	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MDFAHGHL_03700	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MDFAHGHL_03701	1.9e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MDFAHGHL_03702	6.7e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MDFAHGHL_03703	3.33e-33	ykzI	-	-	-	-	-	-	-
MDFAHGHL_03704	1.35e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MDFAHGHL_03705	2.17e-107	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MDFAHGHL_03706	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MDFAHGHL_03707	5.52e-246	ylaA	-	-	-	-	-	-	-
MDFAHGHL_03708	5.38e-61	ylaB	-	-	-	-	-	-	-
MDFAHGHL_03709	8.11e-121	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MDFAHGHL_03711	3.48e-63	ylaE	-	-	-	-	-	-	-
MDFAHGHL_03712	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MDFAHGHL_03713	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MDFAHGHL_03714	3.31e-60	-	-	-	S	-	-	-	YlaH-like protein
MDFAHGHL_03715	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03716	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDFAHGHL_03717	9.42e-314	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MDFAHGHL_03718	2.49e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MDFAHGHL_03719	6.57e-224	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MDFAHGHL_03720	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MDFAHGHL_03721	2.24e-67	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDFAHGHL_03722	1.8e-162	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDFAHGHL_03723	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDFAHGHL_03724	2.85e-213	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MDFAHGHL_03725	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDFAHGHL_03726	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MDFAHGHL_03727	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDFAHGHL_03728	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MDFAHGHL_03729	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MDFAHGHL_03730	4.37e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MDFAHGHL_03731	1.01e-79	ylbA	-	-	S	-	-	-	YugN-like family
MDFAHGHL_03732	3.35e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MDFAHGHL_03733	5.32e-242	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MDFAHGHL_03734	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
MDFAHGHL_03735	2.46e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MDFAHGHL_03736	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MDFAHGHL_03737	2.78e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
MDFAHGHL_03738	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MDFAHGHL_03739	9.7e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDFAHGHL_03740	7.76e-177	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MDFAHGHL_03741	5.67e-64	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MDFAHGHL_03742	1.23e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MDFAHGHL_03743	4.36e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MDFAHGHL_03744	9.04e-296	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MDFAHGHL_03745	1.7e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MDFAHGHL_03746	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MDFAHGHL_03747	1.22e-108	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MDFAHGHL_03748	1.38e-117	ylbP	-	-	K	-	-	-	n-acetyltransferase
MDFAHGHL_03749	4.13e-211	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDFAHGHL_03750	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MDFAHGHL_03751	1.72e-18	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDFAHGHL_03752	2.1e-65	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDFAHGHL_03753	3.5e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDFAHGHL_03754	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MDFAHGHL_03755	1.15e-26	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDFAHGHL_03756	6.04e-273	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDFAHGHL_03757	6.51e-148	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDFAHGHL_03758	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MDFAHGHL_03759	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDFAHGHL_03760	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDFAHGHL_03761	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDFAHGHL_03762	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDFAHGHL_03763	5.69e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDFAHGHL_03764	9.58e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MDFAHGHL_03765	2.67e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDFAHGHL_03766	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDFAHGHL_03767	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDFAHGHL_03769	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MDFAHGHL_03770	1.14e-110	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MDFAHGHL_03771	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_03772	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_03773	1.97e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MDFAHGHL_03774	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MDFAHGHL_03775	7.36e-33	ylmC	-	-	S	-	-	-	sporulation protein
MDFAHGHL_03776	2.74e-205	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MDFAHGHL_03777	5.23e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDFAHGHL_03778	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDFAHGHL_03779	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MDFAHGHL_03780	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MDFAHGHL_03781	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MDFAHGHL_03782	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDFAHGHL_03783	1.79e-84	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MDFAHGHL_03784	1.24e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDFAHGHL_03785	2.65e-216	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDFAHGHL_03786	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDFAHGHL_03787	2.31e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MDFAHGHL_03788	1.26e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MDFAHGHL_03789	2.91e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDFAHGHL_03790	7.32e-169	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDFAHGHL_03791	5.74e-67	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDFAHGHL_03792	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MDFAHGHL_03793	3.54e-181	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MDFAHGHL_03794	7.67e-224	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDFAHGHL_03795	3.66e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDFAHGHL_03796	2.2e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDFAHGHL_03798	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MDFAHGHL_03799	8.54e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MDFAHGHL_03800	5.03e-207	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MDFAHGHL_03801	2.35e-43	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MDFAHGHL_03802	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MDFAHGHL_03803	2.06e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MDFAHGHL_03804	1.76e-188	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MDFAHGHL_03805	1.54e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MDFAHGHL_03806	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MDFAHGHL_03807	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MDFAHGHL_03808	6.32e-168	yloC	-	-	S	-	-	-	stress-induced protein
MDFAHGHL_03809	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MDFAHGHL_03810	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MDFAHGHL_03811	2.71e-14	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDFAHGHL_03812	2.18e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDFAHGHL_03813	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDFAHGHL_03814	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDFAHGHL_03815	4.76e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDFAHGHL_03816	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDFAHGHL_03817	1.52e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDFAHGHL_03818	3.51e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MDFAHGHL_03819	4.91e-33	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDFAHGHL_03820	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDFAHGHL_03821	1.08e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDFAHGHL_03822	2.51e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDFAHGHL_03823	1.84e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MDFAHGHL_03824	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MDFAHGHL_03825	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MDFAHGHL_03826	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MDFAHGHL_03827	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MDFAHGHL_03828	4.14e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MDFAHGHL_03829	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDFAHGHL_03830	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MDFAHGHL_03831	7.71e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDFAHGHL_03832	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_03833	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MDFAHGHL_03834	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDFAHGHL_03835	3.02e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDFAHGHL_03836	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MDFAHGHL_03837	1.08e-223	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDFAHGHL_03838	1.01e-180	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MDFAHGHL_03839	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDFAHGHL_03840	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDFAHGHL_03841	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MDFAHGHL_03842	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MDFAHGHL_03843	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MDFAHGHL_03844	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDFAHGHL_03845	8.4e-178	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MDFAHGHL_03846	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDFAHGHL_03847	7.24e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDFAHGHL_03848	1.01e-52	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDFAHGHL_03849	5.2e-96	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDFAHGHL_03850	0.0	ylqG	-	-	-	-	-	-	-
MDFAHGHL_03851	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MDFAHGHL_03852	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDFAHGHL_03853	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDFAHGHL_03854	1.27e-216	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MDFAHGHL_03855	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDFAHGHL_03856	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDFAHGHL_03857	2.99e-218	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MDFAHGHL_03858	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDFAHGHL_03859	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDFAHGHL_03860	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MDFAHGHL_03861	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MDFAHGHL_03862	2.63e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MDFAHGHL_03863	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MDFAHGHL_03864	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MDFAHGHL_03865	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDFAHGHL_03866	5.06e-125	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MDFAHGHL_03867	4.26e-308	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MDFAHGHL_03868	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MDFAHGHL_03869	1.53e-85	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MDFAHGHL_03870	2.22e-262	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MDFAHGHL_03871	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MDFAHGHL_03872	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MDFAHGHL_03873	1.85e-44	flbD	-	-	N	ko:K02385	-	ko00000,ko02035	protein, possibly involved in motility
MDFAHGHL_03874	1.89e-80	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MDFAHGHL_03875	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDFAHGHL_03876	6.97e-247	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MDFAHGHL_03877	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MDFAHGHL_03878	9.34e-144	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MDFAHGHL_03879	1.48e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MDFAHGHL_03880	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MDFAHGHL_03881	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MDFAHGHL_03882	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDFAHGHL_03883	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDFAHGHL_03884	2.17e-131	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MDFAHGHL_03885	3.83e-201	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MDFAHGHL_03886	2.36e-247	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MDFAHGHL_03887	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MDFAHGHL_03888	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MDFAHGHL_03889	5.91e-143	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MDFAHGHL_03890	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MDFAHGHL_03891	7.95e-76	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_03892	1.42e-71	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDFAHGHL_03893	7.41e-97	ylxL	-	-	-	-	-	-	-
MDFAHGHL_03894	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MDFAHGHL_03895	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDFAHGHL_03896	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MDFAHGHL_03897	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDFAHGHL_03898	7.76e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDFAHGHL_03899	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MDFAHGHL_03900	6.31e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDFAHGHL_03901	9.82e-298	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MDFAHGHL_03902	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDFAHGHL_03903	5.48e-268	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDFAHGHL_03904	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDFAHGHL_03905	3.28e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MDFAHGHL_03906	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MDFAHGHL_03907	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MDFAHGHL_03908	1.83e-38	ylxQ	-	-	J	-	-	-	ribosomal protein
MDFAHGHL_03909	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDFAHGHL_03910	1.58e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MDFAHGHL_03911	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDFAHGHL_03912	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDFAHGHL_03913	1.19e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MDFAHGHL_03914	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDFAHGHL_03915	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDFAHGHL_03916	3.56e-233	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MDFAHGHL_03917	2.51e-300	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MDFAHGHL_03918	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MDFAHGHL_03919	9.9e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MDFAHGHL_03920	4.75e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MDFAHGHL_03921	1.22e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDFAHGHL_03922	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MDFAHGHL_03923	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDFAHGHL_03924	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDFAHGHL_03925	4.12e-170	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MDFAHGHL_03926	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
MDFAHGHL_03927	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDFAHGHL_03928	1.15e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MDFAHGHL_03929	2.72e-270	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MDFAHGHL_03930	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDFAHGHL_03931	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MDFAHGHL_03932	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
MDFAHGHL_03933	1.74e-311	ymfH	-	-	S	-	-	-	zinc protease
MDFAHGHL_03934	2.33e-27	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MDFAHGHL_03935	2.06e-109	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MDFAHGHL_03936	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MDFAHGHL_03937	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MDFAHGHL_03938	1e-179	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MDFAHGHL_03939	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDFAHGHL_03940	8.03e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MDFAHGHL_03941	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDFAHGHL_03942	1.83e-277	pbpX	-	-	V	-	-	-	Beta-lactamase
MDFAHGHL_03943	1.68e-307	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MDFAHGHL_03944	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MDFAHGHL_03945	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MDFAHGHL_03946	1.43e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MDFAHGHL_03947	4.29e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDFAHGHL_03948	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDFAHGHL_03949	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MDFAHGHL_03950	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MDFAHGHL_03951	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDFAHGHL_03952	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDFAHGHL_03954	1.72e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MDFAHGHL_03955	4.92e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_03956	5.25e-233	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MDFAHGHL_03957	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MDFAHGHL_03958	5.27e-49	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MDFAHGHL_03959	1.27e-309	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MDFAHGHL_03960	1.02e-185	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MDFAHGHL_03961	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MDFAHGHL_03962	9.2e-40	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03963	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03964	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03965	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MDFAHGHL_03966	4.89e-188	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03967	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MDFAHGHL_03968	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MDFAHGHL_03969	2.38e-294	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MDFAHGHL_03970	1.81e-103	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MDFAHGHL_03971	4.46e-153	yoaK	-	-	S	-	-	-	Membrane
MDFAHGHL_03972	1.55e-72	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives