ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IGALPHCO_00001 5.93e-55 - - - - - - - -
IGALPHCO_00002 3.01e-36 - - - - - - - -
IGALPHCO_00006 0.0 steT - - E ko:K03294 - ko00000 amino acid
IGALPHCO_00012 3.64e-219 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
IGALPHCO_00016 8.02e-144 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IGALPHCO_00017 2.29e-254 - - - S - - - DUF218 domain
IGALPHCO_00018 2.04e-60 - - - - - - - -
IGALPHCO_00019 1.65e-209 - - - L - - - HNH nucleases
IGALPHCO_00020 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
IGALPHCO_00021 4.29e-255 - - - G - - - Glycosyl hydrolases family 8
IGALPHCO_00022 9.26e-306 - - - M - - - Glycosyl transferase
IGALPHCO_00024 3.24e-153 - - - - - - - -
IGALPHCO_00025 1.14e-23 - - - - - - - -
IGALPHCO_00026 1.64e-84 - - - S - - - Iron-sulphur cluster biosynthesis
IGALPHCO_00027 3.66e-237 ysdE - - P - - - Citrate transporter
IGALPHCO_00028 8.93e-124 lemA - - S ko:K03744 - ko00000 LemA family
IGALPHCO_00029 9.9e-208 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IGALPHCO_00030 7.55e-98 yifK - - E ko:K03293 - ko00000 Amino acid permease
IGALPHCO_00031 1.26e-279 yifK - - E ko:K03293 - ko00000 Amino acid permease
IGALPHCO_00032 6.63e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
IGALPHCO_00033 2.97e-304 - - - E - - - amino acid
IGALPHCO_00034 2.55e-246 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
IGALPHCO_00035 3.31e-208 - - - EG - - - EamA-like transporter family
IGALPHCO_00036 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
IGALPHCO_00037 3.43e-169 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
IGALPHCO_00038 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IGALPHCO_00039 1.7e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IGALPHCO_00040 1.57e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
IGALPHCO_00041 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IGALPHCO_00042 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGALPHCO_00043 6.45e-47 - - - - - - - -
IGALPHCO_00044 1.66e-249 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
IGALPHCO_00045 3.11e-242 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
IGALPHCO_00046 1.41e-114 ymdB - - S - - - Macro domain protein
IGALPHCO_00047 0.0 - - - V - - - ABC transporter transmembrane region
IGALPHCO_00048 5.89e-161 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
IGALPHCO_00049 3.03e-277 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
IGALPHCO_00050 4.69e-202 - - - - - - - -
IGALPHCO_00051 4.49e-93 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
IGALPHCO_00052 7.26e-200 - - - C - - - Domain of unknown function (DUF4931)
IGALPHCO_00053 1.62e-195 - - - K - - - Helix-turn-helix domain, rpiR family
IGALPHCO_00054 1.39e-181 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IGALPHCO_00055 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
IGALPHCO_00056 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGALPHCO_00057 2.16e-208 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IGALPHCO_00058 2.6e-165 - - - - - - - -
IGALPHCO_00059 1.32e-66 - - - - - - - -
IGALPHCO_00060 2.6e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
IGALPHCO_00061 8.05e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
IGALPHCO_00062 5.95e-147 - - - G - - - Phosphoglycerate mutase family
IGALPHCO_00063 4.06e-145 - - - G - - - phosphoglycerate mutase
IGALPHCO_00064 1.91e-119 - - - K - - - Bacterial regulatory proteins, tetR family
IGALPHCO_00065 1.18e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
IGALPHCO_00066 3.13e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00067 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IGALPHCO_00068 1.36e-50 - - - - - - - -
IGALPHCO_00069 1.4e-140 - - - K - - - WHG domain
IGALPHCO_00070 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00071 2.22e-125 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
IGALPHCO_00072 5.19e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IGALPHCO_00073 5.22e-255 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
IGALPHCO_00074 1.24e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IGALPHCO_00075 3.27e-228 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGALPHCO_00076 3.16e-125 cvpA - - S - - - Colicin V production protein
IGALPHCO_00077 1.75e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
IGALPHCO_00078 2.47e-195 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IGALPHCO_00079 5e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
IGALPHCO_00080 4.28e-196 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IGALPHCO_00081 1.23e-56 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
IGALPHCO_00082 1.89e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IGALPHCO_00083 1.03e-179 - - - S - - - Protein of unknown function (DUF1129)
IGALPHCO_00084 5.85e-122 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00085 7.68e-252 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00086 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IGALPHCO_00087 2.39e-156 vanR - - K - - - response regulator
IGALPHCO_00088 4.88e-262 - - - T - - - His Kinase A (phosphoacceptor) domain
IGALPHCO_00089 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGALPHCO_00090 3.17e-185 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IGALPHCO_00091 1.53e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00092 2.34e-283 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IGALPHCO_00093 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
IGALPHCO_00094 1.38e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
IGALPHCO_00095 5.13e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IGALPHCO_00096 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
IGALPHCO_00097 2.82e-44 - - - S - - - YSIRK type signal peptide
IGALPHCO_00098 2.74e-269 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IGALPHCO_00099 4.28e-180 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IGALPHCO_00100 1.07e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
IGALPHCO_00101 5.93e-206 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IGALPHCO_00102 2.22e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IGALPHCO_00103 4.21e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
IGALPHCO_00104 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IGALPHCO_00105 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IGALPHCO_00106 2.87e-269 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IGALPHCO_00107 6.06e-54 - - - - - - - -
IGALPHCO_00108 5.46e-81 - - - - - - - -
IGALPHCO_00109 0.0 - - - S - - - ABC transporter
IGALPHCO_00110 2.11e-175 - - - S - - - Putative threonine/serine exporter
IGALPHCO_00111 2.22e-103 - - - S - - - Threonine/Serine exporter, ThrE
IGALPHCO_00112 1.05e-53 - - - - - - - -
IGALPHCO_00113 7.58e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
IGALPHCO_00114 6.79e-105 - - - - - - - -
IGALPHCO_00115 4.31e-231 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGALPHCO_00116 1.35e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
IGALPHCO_00117 1.11e-142 - - - - - - - -
IGALPHCO_00118 0.0 - - - S - - - O-antigen ligase like membrane protein
IGALPHCO_00119 1.87e-58 - - - - - - - -
IGALPHCO_00120 1.18e-128 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
IGALPHCO_00121 5.52e-164 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
IGALPHCO_00122 2.8e-297 - - - S - - - Putative peptidoglycan binding domain
IGALPHCO_00123 2.13e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGALPHCO_00124 0.0 - - - E - - - Amino Acid
IGALPHCO_00125 2.68e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00126 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IGALPHCO_00127 7.94e-36 - - - L ko:K07483 - ko00000 transposase activity
IGALPHCO_00128 3.55e-21 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
IGALPHCO_00129 5.9e-67 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
IGALPHCO_00130 4.36e-162 gpm2 - - G - - - Phosphoglycerate mutase family
IGALPHCO_00131 1.54e-34 - - - - - - - -
IGALPHCO_00132 1.65e-69 - - - - - - - -
IGALPHCO_00133 2.04e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IGALPHCO_00134 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IGALPHCO_00135 2.81e-165 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IGALPHCO_00136 3.25e-185 - - - K - - - Helix-turn-helix domain, rpiR family
IGALPHCO_00137 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
IGALPHCO_00139 5.92e-150 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
IGALPHCO_00140 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IGALPHCO_00141 8.72e-160 - - - S - - - Peptidase_C39 like family
IGALPHCO_00142 1.54e-131 - - - E - - - GDSL-like Lipase/Acylhydrolase
IGALPHCO_00143 7.58e-210 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IGALPHCO_00144 1.13e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGALPHCO_00146 5.64e-176 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00147 8.58e-228 - - - S - - - Conserved hypothetical protein 698
IGALPHCO_00148 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
IGALPHCO_00149 1.03e-106 - - - S - - - Pyridoxamine 5'-phosphate oxidase
IGALPHCO_00150 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IGALPHCO_00151 2.1e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IGALPHCO_00152 6.17e-85 - - - S - - - Protein of unknown function (DUF3021)
IGALPHCO_00153 1.9e-259 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
IGALPHCO_00154 6.11e-41 - - - K - - - LytTr DNA-binding domain
IGALPHCO_00157 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
IGALPHCO_00158 1.34e-139 ybbB - - S - - - Protein of unknown function (DUF1211)
IGALPHCO_00160 2.26e-142 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
IGALPHCO_00161 1.2e-150 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
IGALPHCO_00162 1.55e-158 - - - T - - - Transcriptional regulatory protein, C terminal
IGALPHCO_00163 6.7e-227 - - - T - - - GHKL domain
IGALPHCO_00164 2.13e-115 ykoJ - - S - - - Peptidase propeptide and YPEB domain
IGALPHCO_00165 1.9e-13 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IGALPHCO_00166 1.88e-44 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IGALPHCO_00167 1.21e-101 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IGALPHCO_00168 1.89e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IGALPHCO_00169 7.14e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
IGALPHCO_00170 1.08e-289 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
IGALPHCO_00171 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGALPHCO_00172 8.45e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
IGALPHCO_00173 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
IGALPHCO_00174 7.21e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
IGALPHCO_00175 1.24e-185 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IGALPHCO_00176 4.88e-140 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IGALPHCO_00177 1.97e-173 - - - H - - - Nodulation protein S (NodS)
IGALPHCO_00178 1.23e-173 - - - S - - - PFAM Archaeal ATPase
IGALPHCO_00179 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
IGALPHCO_00181 3.26e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
IGALPHCO_00182 2.87e-112 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGALPHCO_00183 1.79e-216 - - - S ko:K07045 - ko00000 Amidohydrolase
IGALPHCO_00184 2.01e-39 - - - - - - - -
IGALPHCO_00185 1.25e-195 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IGALPHCO_00186 2.15e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IGALPHCO_00187 4.4e-213 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
IGALPHCO_00188 2.26e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
IGALPHCO_00189 1.62e-149 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IGALPHCO_00190 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGALPHCO_00191 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGALPHCO_00192 6.88e-230 - - - K - - - Transcriptional regulator
IGALPHCO_00193 1.42e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
IGALPHCO_00194 6.87e-258 napA - - P - - - Sodium/hydrogen exchanger family
IGALPHCO_00195 0.0 cadA - - P - - - P-type ATPase
IGALPHCO_00196 4.76e-111 ykuL - - S - - - (CBS) domain
IGALPHCO_00200 2.34e-212 - - - K - - - helix_turn_helix, arabinose operon control protein
IGALPHCO_00201 1.6e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IGALPHCO_00202 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00203 6.57e-144 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IGALPHCO_00204 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IGALPHCO_00205 6.78e-236 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
IGALPHCO_00206 3.05e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
IGALPHCO_00207 1.05e-186 yycI - - S - - - YycH protein
IGALPHCO_00208 0.0 yycH - - S - - - YycH protein
IGALPHCO_00209 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGALPHCO_00210 2.49e-166 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IGALPHCO_00211 9.19e-177 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
IGALPHCO_00212 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IGALPHCO_00213 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
IGALPHCO_00214 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
IGALPHCO_00215 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IGALPHCO_00216 0.0 - - - E - - - Phospholipase B
IGALPHCO_00217 1.99e-144 - - - I - - - Acid phosphatase homologues
IGALPHCO_00218 0.0 - - - E - - - amino acid
IGALPHCO_00219 2.38e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
IGALPHCO_00220 4.49e-39 - - - - - - - -
IGALPHCO_00221 4.36e-89 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGALPHCO_00222 2.04e-107 - - - - - - - -
IGALPHCO_00223 7.25e-265 pepA - - E - - - M42 glutamyl aminopeptidase
IGALPHCO_00225 3.97e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00226 4.05e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
IGALPHCO_00227 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
IGALPHCO_00228 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IGALPHCO_00229 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
IGALPHCO_00230 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
IGALPHCO_00231 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
IGALPHCO_00232 0.0 - - - E - - - Peptidase family C69
IGALPHCO_00233 2.99e-272 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
IGALPHCO_00234 5.71e-201 - - - S - - - Alpha beta hydrolase
IGALPHCO_00235 2.08e-87 - - - K - - - Transcriptional regulator, MarR family
IGALPHCO_00236 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00237 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
IGALPHCO_00238 2.53e-66 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
IGALPHCO_00239 2.16e-109 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_00240 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
IGALPHCO_00241 1.87e-218 - - - K - - - LysR substrate binding domain
IGALPHCO_00242 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IGALPHCO_00243 9.38e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IGALPHCO_00244 1.09e-171 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IGALPHCO_00245 8.35e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
IGALPHCO_00246 5.19e-111 - - - S - - - Peptidase propeptide and YPEB domain
IGALPHCO_00247 8.77e-237 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IGALPHCO_00248 2.59e-103 - - - P - - - Major Facilitator Superfamily
IGALPHCO_00249 4.31e-191 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_00250 1.75e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_00251 3.24e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_00252 9.75e-85 - - - - - - - -
IGALPHCO_00253 1.37e-108 - - - S - - - Putative adhesin
IGALPHCO_00255 2.24e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IGALPHCO_00257 1.01e-274 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IGALPHCO_00258 0.0 mdr - - EGP - - - Major Facilitator
IGALPHCO_00259 1.1e-146 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IGALPHCO_00260 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IGALPHCO_00261 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
IGALPHCO_00262 4.64e-277 - - - S - - - Protein of unknown function (DUF2974)
IGALPHCO_00263 1.68e-175 - - - - - - - -
IGALPHCO_00264 1.1e-192 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGALPHCO_00265 9.66e-221 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IGALPHCO_00266 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IGALPHCO_00267 3.79e-221 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
IGALPHCO_00268 3.25e-64 - - - - - - - -
IGALPHCO_00269 4.31e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
IGALPHCO_00270 2.33e-165 - - - F - - - Glutamine amidotransferase class-I
IGALPHCO_00271 3.4e-138 ylbE - - GM - - - NAD(P)H-binding
IGALPHCO_00272 2.33e-103 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IGALPHCO_00273 3.65e-227 - - - P - - - Voltage gated chloride channel
IGALPHCO_00274 8.45e-238 - - - S - - - Bacteriocin helveticin-J
IGALPHCO_00275 2.64e-122 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
IGALPHCO_00276 6.31e-203 - - - S ko:K07088 - ko00000 Membrane transport protein
IGALPHCO_00277 3.1e-175 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
IGALPHCO_00278 9.83e-185 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IGALPHCO_00279 0.0 qacA - - EGP - - - Major Facilitator
IGALPHCO_00280 0.0 qacA - - EGP - - - Major Facilitator
IGALPHCO_00281 2.17e-88 - - - - - - - -
IGALPHCO_00282 8.11e-61 ybfG - - M - - - peptidoglycan-binding domain-containing protein
IGALPHCO_00284 7.68e-23 - - - - - - - -
IGALPHCO_00285 8.68e-100 - - - K - - - acetyltransferase
IGALPHCO_00286 4.4e-59 - - - S - - - PFAM Archaeal ATPase
IGALPHCO_00287 1.28e-161 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IGALPHCO_00288 8.93e-25 - - - K - - - Transcriptional regulator
IGALPHCO_00289 4.22e-304 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
IGALPHCO_00290 8.92e-105 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGALPHCO_00291 5.88e-256 - - - S - - - PFAM Archaeal ATPase
IGALPHCO_00292 3.18e-114 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
IGALPHCO_00293 8.88e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IGALPHCO_00294 5.61e-227 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
IGALPHCO_00295 2.12e-115 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
IGALPHCO_00296 5.77e-81 yugI - - J ko:K07570 - ko00000 general stress protein
IGALPHCO_00297 7.44e-230 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IGALPHCO_00298 9.8e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
IGALPHCO_00299 1.52e-134 - - - S - - - Protein of unknown function (DUF1461)
IGALPHCO_00300 2.82e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IGALPHCO_00301 1.97e-124 yutD - - S - - - Protein of unknown function (DUF1027)
IGALPHCO_00302 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IGALPHCO_00303 1.15e-73 - - - - - - - -
IGALPHCO_00304 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IGALPHCO_00305 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
IGALPHCO_00306 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
IGALPHCO_00307 1.38e-227 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IGALPHCO_00308 1.21e-267 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
IGALPHCO_00309 1.09e-63 - - - - - - - -
IGALPHCO_00310 2.92e-37 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IGALPHCO_00311 3.9e-167 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
IGALPHCO_00312 1.05e-271 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGALPHCO_00313 3.6e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IGALPHCO_00314 9.32e-182 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IGALPHCO_00315 3.65e-90 yslB - - S - - - Protein of unknown function (DUF2507)
IGALPHCO_00316 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00317 8.93e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IGALPHCO_00318 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IGALPHCO_00319 1.88e-118 cvpA - - S - - - Colicin V production protein
IGALPHCO_00320 3.49e-55 yrzB - - S - - - Belongs to the UPF0473 family
IGALPHCO_00321 1.01e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IGALPHCO_00322 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
IGALPHCO_00323 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IGALPHCO_00324 2.28e-294 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IGALPHCO_00325 1.24e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
IGALPHCO_00326 2.72e-262 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGALPHCO_00327 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGALPHCO_00328 1.99e-67 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
IGALPHCO_00329 9.41e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IGALPHCO_00330 1.79e-131 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IGALPHCO_00331 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IGALPHCO_00332 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IGALPHCO_00333 3.14e-90 - - - EGP - - - Major facilitator Superfamily
IGALPHCO_00334 2.32e-76 - - - - - - - -
IGALPHCO_00335 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
IGALPHCO_00336 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IGALPHCO_00337 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IGALPHCO_00338 6.76e-168 - - - S - - - membrane
IGALPHCO_00339 6.68e-103 - - - K - - - LytTr DNA-binding domain
IGALPHCO_00340 5.73e-34 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IGALPHCO_00341 6.28e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IGALPHCO_00342 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IGALPHCO_00343 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
IGALPHCO_00344 2.9e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGALPHCO_00345 5.91e-125 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IGALPHCO_00346 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
IGALPHCO_00347 2.34e-215 yibE - - S - - - overlaps another CDS with the same product name
IGALPHCO_00348 1.88e-154 yibF - - S - - - overlaps another CDS with the same product name
IGALPHCO_00349 8.43e-197 - - - I - - - alpha/beta hydrolase fold
IGALPHCO_00350 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
IGALPHCO_00351 3.01e-164 - - - K ko:K03710 - ko00000,ko03000 UTRA
IGALPHCO_00352 1.09e-271 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
IGALPHCO_00353 3.6e-289 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGALPHCO_00354 1.13e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IGALPHCO_00355 1.63e-190 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
IGALPHCO_00356 1.02e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
IGALPHCO_00357 2.19e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IGALPHCO_00359 5.91e-180 - - - L - - - oxidized base lesion DNA N-glycosylase activity
IGALPHCO_00360 1.81e-310 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGALPHCO_00361 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IGALPHCO_00362 4.71e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGALPHCO_00363 1.07e-205 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
IGALPHCO_00364 9.73e-90 - - - - - - - -
IGALPHCO_00365 3.06e-144 - - - - - - - -
IGALPHCO_00366 1.61e-55 - - - - - - - -
IGALPHCO_00367 2.81e-292 - - - D - - - nuclear chromosome segregation
IGALPHCO_00368 8.26e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IGALPHCO_00369 1.83e-124 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
IGALPHCO_00370 7.13e-169 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
IGALPHCO_00371 2.13e-111 - - - S - - - ECF transporter, substrate-specific component
IGALPHCO_00372 2.23e-178 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
IGALPHCO_00373 6.9e-198 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IGALPHCO_00374 3.33e-78 yabA - - L - - - Involved in initiation control of chromosome replication
IGALPHCO_00375 1.62e-196 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IGALPHCO_00376 1.24e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
IGALPHCO_00377 1.45e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGALPHCO_00378 3.03e-44 - - - S - - - Protein of unknown function (DUF2508)
IGALPHCO_00379 8.84e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IGALPHCO_00380 6.62e-69 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IGALPHCO_00381 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGALPHCO_00382 3.38e-109 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IGALPHCO_00383 9.83e-66 - - - S - - - Protein conserved in bacteria
IGALPHCO_00384 8.77e-190 - - - - - - - -
IGALPHCO_00385 3.9e-30 - - - - - - - -
IGALPHCO_00386 1.25e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IGALPHCO_00387 3.25e-44 - - - - - - - -
IGALPHCO_00388 3.82e-182 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
IGALPHCO_00389 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IGALPHCO_00390 1.78e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IGALPHCO_00391 4.48e-185 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_00392 2.23e-150 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
IGALPHCO_00393 1.96e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
IGALPHCO_00394 2.48e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IGALPHCO_00395 1.89e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IGALPHCO_00396 5.22e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IGALPHCO_00397 8.06e-17 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IGALPHCO_00398 1.48e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IGALPHCO_00399 4.51e-238 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IGALPHCO_00400 3.94e-290 - - - G - - - Major Facilitator Superfamily
IGALPHCO_00401 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGALPHCO_00402 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IGALPHCO_00403 5.9e-46 - - - - - - - -
IGALPHCO_00404 3.08e-115 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
IGALPHCO_00405 1.39e-180 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGALPHCO_00406 5.57e-104 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IGALPHCO_00407 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IGALPHCO_00408 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGALPHCO_00409 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IGALPHCO_00410 3.82e-133 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
IGALPHCO_00411 2.2e-239 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IGALPHCO_00412 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IGALPHCO_00413 3.11e-250 - - - M - - - transferase activity, transferring glycosyl groups
IGALPHCO_00414 7.46e-201 - - - S - - - glycosyl transferase family 2
IGALPHCO_00415 3.04e-35 - - - UW - - - Tetratricopeptide repeat
IGALPHCO_00416 5.23e-93 - - - S - - - Phage tail tube protein
IGALPHCO_00417 2.27e-62 - - - - - - - -
IGALPHCO_00418 1.01e-55 - - - - - - - -
IGALPHCO_00419 4.96e-42 - - - S - - - Phage head-tail joining protein
IGALPHCO_00420 1.05e-62 - - - S - - - Phage gp6-like head-tail connector protein
IGALPHCO_00422 4.92e-191 - - - S - - - Phage capsid family
IGALPHCO_00423 6.45e-112 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
IGALPHCO_00424 1.53e-177 - - - S - - - portal protein
IGALPHCO_00426 6.7e-275 - - - L - - - Terminase
IGALPHCO_00427 1.03e-65 - - - L - - - Terminase
IGALPHCO_00428 4.74e-65 - - - L - - - Phage terminase, small subunit
IGALPHCO_00429 1.64e-07 - - - - - - - -
IGALPHCO_00445 1.54e-90 - - - K - - - ORF6N domain
IGALPHCO_00448 1.89e-52 - - - S - - - Transcriptional regulator, RinA family
IGALPHCO_00453 4.62e-31 - - - S - - - Bacteriocin class II with double-glycine leader peptide
IGALPHCO_00454 6.99e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
IGALPHCO_00455 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IGALPHCO_00456 3.14e-184 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IGALPHCO_00457 1.23e-155 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
IGALPHCO_00458 6.57e-40 - - - S - - - magnesium ion binding
IGALPHCO_00466 1.52e-21 ansR - - K - - - Transcriptional regulator
IGALPHCO_00468 1.17e-18 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
IGALPHCO_00470 2.42e-52 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGALPHCO_00473 3.04e-103 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
IGALPHCO_00474 1.17e-31 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
IGALPHCO_00476 4.65e-46 - - - S - - - ERF superfamily
IGALPHCO_00477 5.36e-57 - - - L - - - DnaD domain protein
IGALPHCO_00478 6e-73 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
IGALPHCO_00479 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
IGALPHCO_00480 1.5e-231 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
IGALPHCO_00481 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IGALPHCO_00482 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IGALPHCO_00483 2.07e-218 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
IGALPHCO_00484 7.76e-287 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGALPHCO_00485 4.93e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
IGALPHCO_00486 4.61e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
IGALPHCO_00487 2.79e-193 yleF - - K - - - Helix-turn-helix domain, rpiR family
IGALPHCO_00488 1.06e-239 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
IGALPHCO_00489 5.88e-201 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IGALPHCO_00490 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGALPHCO_00491 1.8e-167 - - - S ko:K07090 - ko00000 membrane transporter protein
IGALPHCO_00492 2.84e-203 - - - S - - - Aldo/keto reductase family
IGALPHCO_00493 9.42e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IGALPHCO_00501 9.3e-45 - - - - - - - -
IGALPHCO_00502 7.31e-105 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
IGALPHCO_00504 8.62e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
IGALPHCO_00509 2.45e-25 - - - - - - - -
IGALPHCO_00510 7.79e-112 - - - L ko:K07491 - ko00000 Transposase IS200 like
IGALPHCO_00511 0.0 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
IGALPHCO_00512 2.67e-204 int3 - - L - - - Belongs to the 'phage' integrase family
IGALPHCO_00513 2.56e-148 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
IGALPHCO_00514 4.26e-170 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGALPHCO_00515 8.49e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IGALPHCO_00516 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IGALPHCO_00517 3.74e-48 yozE - - S - - - Belongs to the UPF0346 family
IGALPHCO_00518 2.03e-190 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
IGALPHCO_00519 2.78e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
IGALPHCO_00520 4.74e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IGALPHCO_00521 4.7e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGALPHCO_00522 4.17e-134 - - - J ko:K10716 - ko00000,ko02000 Ion transport protein
IGALPHCO_00523 3.05e-36 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00527 3.44e-282 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
IGALPHCO_00528 6.12e-278 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IGALPHCO_00529 9.41e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
IGALPHCO_00531 9.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
IGALPHCO_00532 1.34e-261 - - - EGP - - - Major Facilitator Superfamily
IGALPHCO_00533 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IGALPHCO_00534 1.58e-209 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IGALPHCO_00535 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
IGALPHCO_00536 2.09e-76 yqhL - - P - - - Rhodanese-like protein
IGALPHCO_00537 3.31e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
IGALPHCO_00538 2.67e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
IGALPHCO_00539 1.67e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGALPHCO_00540 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IGALPHCO_00541 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IGALPHCO_00542 0.0 - - - S - - - membrane
IGALPHCO_00543 1.9e-259 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
IGALPHCO_00544 5.34e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGALPHCO_00545 6.41e-261 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IGALPHCO_00546 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGALPHCO_00547 3.68e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IGALPHCO_00548 4.83e-82 yodB - - K - - - Transcriptional regulator, HxlR family
IGALPHCO_00549 3.14e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGALPHCO_00550 8.53e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IGALPHCO_00551 5.26e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGALPHCO_00552 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00553 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGALPHCO_00554 1.89e-169 csrR - - K - - - response regulator
IGALPHCO_00555 3.13e-122 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
IGALPHCO_00556 4.15e-279 ylbM - - S - - - Belongs to the UPF0348 family
IGALPHCO_00557 4.36e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IGALPHCO_00558 1.47e-142 yqeK - - H - - - Hydrolase, HD family
IGALPHCO_00559 9.54e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGALPHCO_00560 1.59e-268 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
IGALPHCO_00561 6.66e-115 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
IGALPHCO_00562 6.48e-243 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IGALPHCO_00563 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IGALPHCO_00564 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IGALPHCO_00565 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGALPHCO_00566 8.78e-302 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IGALPHCO_00567 1.43e-95 - - - S - - - Protein of unknown function (DUF3021)
IGALPHCO_00568 9.31e-97 - - - K - - - LytTr DNA-binding domain
IGALPHCO_00569 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGALPHCO_00570 1.4e-204 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IGALPHCO_00571 6.38e-314 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
IGALPHCO_00572 1.2e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IGALPHCO_00573 3.74e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IGALPHCO_00574 8.18e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IGALPHCO_00575 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGALPHCO_00576 1.11e-77 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IGALPHCO_00577 1.05e-97 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IGALPHCO_00578 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IGALPHCO_00579 3.96e-111 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
IGALPHCO_00580 8.43e-155 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGALPHCO_00581 1.11e-70 ytpP - - CO - - - Thioredoxin
IGALPHCO_00582 5.68e-83 - - - - - - - -
IGALPHCO_00583 9.86e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IGALPHCO_00584 4.34e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IGALPHCO_00585 1.14e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00586 9.69e-99 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
IGALPHCO_00587 3.74e-80 - - - - - - - -
IGALPHCO_00588 9.85e-47 - - - S - - - YtxH-like protein
IGALPHCO_00589 3.04e-203 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IGALPHCO_00590 4.39e-12 yxeH - - S - - - hydrolase
IGALPHCO_00591 7.61e-16 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
IGALPHCO_00592 7.18e-242 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IGALPHCO_00593 3.9e-43 - - - S - - - SnoaL-like domain
IGALPHCO_00594 3.84e-146 - - - C - - - nitroreductase
IGALPHCO_00595 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00596 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
IGALPHCO_00597 8.09e-260 - - - M - - - Glycosyl transferases group 1
IGALPHCO_00598 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IGALPHCO_00599 2.7e-137 pncA - - Q - - - Isochorismatase family
IGALPHCO_00600 1.14e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IGALPHCO_00601 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
IGALPHCO_00602 3.7e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IGALPHCO_00603 1.97e-295 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IGALPHCO_00604 6.55e-224 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IGALPHCO_00605 3.04e-119 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IGALPHCO_00606 9.2e-214 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IGALPHCO_00607 7.14e-166 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IGALPHCO_00608 3.72e-152 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IGALPHCO_00609 0.0 - - - I - - - Protein of unknown function (DUF2974)
IGALPHCO_00610 3.21e-95 yxeH - - S - - - hydrolase
IGALPHCO_00611 1.05e-69 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
IGALPHCO_00612 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGALPHCO_00613 2.58e-103 - - - - - - - -
IGALPHCO_00614 1.9e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
IGALPHCO_00615 6.09e-113 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
IGALPHCO_00616 2.41e-165 terC - - P - - - Integral membrane protein TerC family
IGALPHCO_00617 1.18e-83 yeaO - - S - - - Protein of unknown function, DUF488
IGALPHCO_00618 5.3e-150 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IGALPHCO_00619 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_00620 1.67e-213 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_00621 1.38e-230 - - - S - - - DUF218 domain
IGALPHCO_00622 5.06e-68 ybjQ - - S - - - Belongs to the UPF0145 family
IGALPHCO_00623 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
IGALPHCO_00624 6.25e-221 - - - - - - - -
IGALPHCO_00625 3.66e-167 - - - - - - - -
IGALPHCO_00626 7.06e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGALPHCO_00627 5.06e-31 - - - - - - - -
IGALPHCO_00628 7.85e-180 - - - - - - - -
IGALPHCO_00629 7.71e-188 - - - - - - - -
IGALPHCO_00630 7.68e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IGALPHCO_00631 5.15e-79 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
IGALPHCO_00632 5.38e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IGALPHCO_00633 1.57e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGALPHCO_00634 4.32e-154 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IGALPHCO_00635 1.13e-191 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_00636 1.14e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00637 4.22e-144 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
IGALPHCO_00638 2.79e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
IGALPHCO_00639 1.84e-209 - - - M - - - domain protein
IGALPHCO_00641 4.34e-110 - - - - - - - -
IGALPHCO_00642 1.19e-171 - - - - - - - -
IGALPHCO_00643 8.64e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IGALPHCO_00644 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IGALPHCO_00645 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IGALPHCO_00646 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IGALPHCO_00647 4.44e-172 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IGALPHCO_00648 2.36e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IGALPHCO_00649 1.97e-113 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IGALPHCO_00650 4.08e-221 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
IGALPHCO_00651 7.36e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
IGALPHCO_00652 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IGALPHCO_00653 3.44e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IGALPHCO_00654 2.53e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
IGALPHCO_00655 6.79e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IGALPHCO_00656 2.5e-154 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
IGALPHCO_00657 2.23e-202 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGALPHCO_00658 1.09e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGALPHCO_00659 8.96e-12 - - - - - - - -
IGALPHCO_00660 1.74e-175 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IGALPHCO_00661 1.82e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IGALPHCO_00662 1.11e-283 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IGALPHCO_00663 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IGALPHCO_00664 3.67e-313 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IGALPHCO_00665 1.43e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IGALPHCO_00666 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGALPHCO_00667 3.71e-83 - - - - - - - -
IGALPHCO_00668 2.64e-217 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
IGALPHCO_00669 2.96e-111 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IGALPHCO_00670 3.64e-219 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
IGALPHCO_00671 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IGALPHCO_00672 3.11e-268 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IGALPHCO_00673 7.3e-52 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
IGALPHCO_00674 8.92e-55 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGALPHCO_00675 1.25e-236 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
IGALPHCO_00676 0.0 yhaN - - L - - - AAA domain
IGALPHCO_00677 1.1e-276 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
IGALPHCO_00678 1.29e-72 yheA - - S - - - Belongs to the UPF0342 family
IGALPHCO_00679 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IGALPHCO_00680 4.34e-179 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IGALPHCO_00681 3.7e-118 int3 - - L - - - Belongs to the 'phage' integrase family
IGALPHCO_00682 2.41e-24 ansR - - K - - - Transcriptional regulator
IGALPHCO_00683 5.05e-20 - - - - - - - -
IGALPHCO_00689 4.3e-36 - - - - - - - -
IGALPHCO_00691 1.94e-32 - - - - - - - -
IGALPHCO_00697 7.64e-37 - - - H - - - RibD C-terminal domain
IGALPHCO_00698 1.36e-99 - - - L - - - NUDIX domain
IGALPHCO_00699 1.37e-176 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
IGALPHCO_00700 1.04e-244 flp - - V - - - Beta-lactamase
IGALPHCO_00701 5.08e-83 ung2 - - L - - - Uracil-DNA glycosylase
IGALPHCO_00702 7.88e-21 ung2 - - L - - - Uracil-DNA glycosylase
IGALPHCO_00703 4.63e-144 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
IGALPHCO_00704 1.82e-123 dpsB - - P - - - Belongs to the Dps family
IGALPHCO_00705 6.45e-45 - - - C - - - Heavy-metal-associated domain
IGALPHCO_00706 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
IGALPHCO_00707 1.27e-64 - - - - - - - -
IGALPHCO_00708 5.43e-43 - - - - - - - -
IGALPHCO_00709 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGALPHCO_00710 1.54e-147 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IGALPHCO_00711 1.5e-162 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00712 9.63e-306 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
IGALPHCO_00713 2.99e-189 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
IGALPHCO_00714 7.45e-94 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
IGALPHCO_00715 9.96e-129 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00716 6.3e-130 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00717 8.55e-183 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
IGALPHCO_00718 3.82e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
IGALPHCO_00719 9.25e-50 - - - M - - - family 8
IGALPHCO_00720 1.17e-41 - - - UW - - - Tetratricopeptide repeat
IGALPHCO_00722 4.33e-194 - - - S - - - hydrolase
IGALPHCO_00723 7.28e-213 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
IGALPHCO_00724 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGALPHCO_00725 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IGALPHCO_00726 2.23e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGALPHCO_00727 1.12e-264 camS - - S - - - sex pheromone
IGALPHCO_00728 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGALPHCO_00729 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IGALPHCO_00730 2.71e-143 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
IGALPHCO_00731 5.63e-130 - - - S - - - ECF transporter, substrate-specific component
IGALPHCO_00733 4.7e-103 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IGALPHCO_00734 7.45e-167 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
IGALPHCO_00735 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
IGALPHCO_00736 7.83e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IGALPHCO_00737 3.34e-176 - - - - - - - -
IGALPHCO_00738 0.0 - - - V - - - ABC transporter transmembrane region
IGALPHCO_00739 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
IGALPHCO_00740 0.0 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
IGALPHCO_00741 1.58e-199 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IGALPHCO_00742 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGALPHCO_00743 0.0 - - - S - - - Glycosyltransferase like family 2
IGALPHCO_00744 6.68e-262 - - - M - - - Glycosyl transferases group 1
IGALPHCO_00745 3.97e-173 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IGALPHCO_00746 1.44e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
IGALPHCO_00747 1.9e-259 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
IGALPHCO_00748 2.57e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
IGALPHCO_00749 3.79e-237 - - - - - - - -
IGALPHCO_00750 4.34e-63 XK27_05625 - - P - - - Rhodanese Homology Domain
IGALPHCO_00753 1.71e-211 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
IGALPHCO_00754 9.91e-46 - - - K - - - SIS domain
IGALPHCO_00755 2.51e-49 - - - S - - - Bacterial protein of unknown function (DUF898)
IGALPHCO_00757 5.02e-166 - - - M - - - LysM domain protein
IGALPHCO_00758 5.68e-174 - - - S - - - Putative ABC-transporter type IV
IGALPHCO_00759 4.9e-76 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
IGALPHCO_00760 8.39e-114 - - - K - - - acetyltransferase
IGALPHCO_00762 1.21e-207 yvgN - - C - - - Aldo keto reductase
IGALPHCO_00763 4.84e-312 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
IGALPHCO_00764 1.8e-269 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
IGALPHCO_00765 2.04e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
IGALPHCO_00766 1.66e-98 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IGALPHCO_00767 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
IGALPHCO_00768 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
IGALPHCO_00769 0.0 - - - S - - - TerB-C domain
IGALPHCO_00770 1.97e-53 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IGALPHCO_00771 2.5e-71 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
IGALPHCO_00772 2.91e-94 - - - - - - - -
IGALPHCO_00773 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_00774 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
IGALPHCO_00775 4.14e-311 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
IGALPHCO_00776 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00777 5.05e-289 - - - L - - - Phage tail tape measure protein TP901
IGALPHCO_00778 9.83e-88 - - - S - - - Phage tail protein
IGALPHCO_00779 0.0 - - - S - - - Phage minor structural protein
IGALPHCO_00780 1.7e-65 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
IGALPHCO_00786 2e-130 - - - M - - - lysozyme activity
IGALPHCO_00787 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGALPHCO_00788 1.39e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IGALPHCO_00789 1.27e-220 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
IGALPHCO_00790 1.9e-115 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IGALPHCO_00791 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IGALPHCO_00792 8.34e-229 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IGALPHCO_00793 2.38e-124 - - - K - - - LysR substrate binding domain
IGALPHCO_00794 5.82e-130 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IGALPHCO_00796 1.24e-94 - - - - - - - -
IGALPHCO_00797 1.9e-259 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
IGALPHCO_00799 3.05e-98 - - - P - - - Major Facilitator Superfamily
IGALPHCO_00800 2.49e-56 - - - M - - - LPXTG-motif cell wall anchor domain protein
IGALPHCO_00801 0.0 - - - M - - - domain protein
IGALPHCO_00802 4.88e-197 arbx - - M - - - Glycosyl transferase family 8
IGALPHCO_00803 9.44e-187 - - - I - - - Acyl-transferase
IGALPHCO_00804 0.0 - - - S - - - domain, Protein
IGALPHCO_00805 1.59e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGALPHCO_00806 3.49e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
IGALPHCO_00807 2.18e-269 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGALPHCO_00808 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
IGALPHCO_00809 6.19e-224 ydbI - - K - - - AI-2E family transporter
IGALPHCO_00810 5.06e-36 - - - - - - - -
IGALPHCO_00811 9.66e-221 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IGALPHCO_00812 6.15e-180 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGALPHCO_00814 1.66e-219 - - - S - - - Protein of unknown function (DUF1002)
IGALPHCO_00815 8.79e-201 epsV - - S - - - glycosyl transferase family 2
IGALPHCO_00816 1.99e-160 - - - S - - - Alpha/beta hydrolase family
IGALPHCO_00817 5.4e-80 - - - - - - - -
IGALPHCO_00818 1.75e-229 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGALPHCO_00819 5.58e-306 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
IGALPHCO_00820 1.13e-145 - - - K - - - Bacterial regulatory proteins, tetR family
IGALPHCO_00821 1.39e-162 - - - - - - - -
IGALPHCO_00822 0.0 - - - S - - - Cysteine-rich secretory protein family
IGALPHCO_00823 3.19e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IGALPHCO_00824 3.79e-142 - - - - - - - -
IGALPHCO_00825 4.84e-36 - - - G - - - Transmembrane secretion effector
IGALPHCO_00826 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
IGALPHCO_00827 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
IGALPHCO_00828 1.58e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IGALPHCO_00829 4.33e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
IGALPHCO_00830 2.03e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
IGALPHCO_00831 2.02e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
IGALPHCO_00832 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IGALPHCO_00833 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IGALPHCO_00834 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IGALPHCO_00835 1.32e-117 ypmB - - S - - - Protein conserved in bacteria
IGALPHCO_00836 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
IGALPHCO_00837 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
IGALPHCO_00838 9.5e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGALPHCO_00839 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
IGALPHCO_00840 7.52e-148 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IGALPHCO_00841 9.33e-136 ypsA - - S - - - Belongs to the UPF0398 family
IGALPHCO_00842 2.08e-55 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IGALPHCO_00843 1.55e-273 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IGALPHCO_00844 3.9e-308 cpdA - - S - - - Calcineurin-like phosphoesterase
IGALPHCO_00845 5.48e-232 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
IGALPHCO_00846 2.29e-223 degV1 - - S - - - DegV family
IGALPHCO_00847 1.78e-73 - - - - - - - -
IGALPHCO_00848 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
IGALPHCO_00849 1.02e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IGALPHCO_00850 1.95e-218 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IGALPHCO_00851 1.8e-249 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IGALPHCO_00852 1.48e-90 - - - - - - - -
IGALPHCO_00853 6.93e-88 - - - S - - - Domain of unknown function DUF1828
IGALPHCO_00854 8.62e-152 - - - S - - - Rib/alpha-like repeat
IGALPHCO_00855 4.98e-10 - - - - - - - -
IGALPHCO_00856 4.33e-314 yagE - - E - - - amino acid
IGALPHCO_00857 2.58e-139 - - - GM - - - NmrA-like family
IGALPHCO_00858 8.38e-189 - - - L - - - Phage integrase, N-terminal SAM-like domain
IGALPHCO_00859 6.86e-130 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
IGALPHCO_00860 6.8e-221 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
IGALPHCO_00861 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IGALPHCO_00862 7.6e-306 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IGALPHCO_00863 0.0 oatA - - I - - - Acyltransferase
IGALPHCO_00864 2.79e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IGALPHCO_00865 7.14e-185 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGALPHCO_00866 8.03e-63 - - - S - - - Lipopolysaccharide assembly protein A domain
IGALPHCO_00867 3.88e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IGALPHCO_00868 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IGALPHCO_00869 7.45e-36 - - - S - - - Protein of unknown function (DUF2929)
IGALPHCO_00870 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IGALPHCO_00871 1.69e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IGALPHCO_00872 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IGALPHCO_00873 9.56e-211 yitL - - S ko:K00243 - ko00000 S1 domain
IGALPHCO_00874 3.91e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
IGALPHCO_00875 1.95e-82 ribT - - K ko:K02859 - ko00000 acetyltransferase
IGALPHCO_00876 1.23e-172 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IGALPHCO_00877 1.59e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IGALPHCO_00878 1.38e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IGALPHCO_00879 2.37e-107 - - - M - - - Lysin motif
IGALPHCO_00880 7.74e-124 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IGALPHCO_00881 1.78e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IGALPHCO_00882 6.93e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IGALPHCO_00883 4.29e-311 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IGALPHCO_00884 1.37e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGALPHCO_00885 1.17e-297 XK27_05225 - - S - - - Tetratricopeptide repeat protein
IGALPHCO_00886 3.6e-101 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IGALPHCO_00887 1.29e-96 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGALPHCO_00888 4.11e-75 - - - - - - - -
IGALPHCO_00889 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
IGALPHCO_00890 3.06e-158 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IGALPHCO_00891 6.92e-173 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGALPHCO_00892 4.21e-214 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGALPHCO_00893 1.21e-190 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGALPHCO_00894 5.17e-166 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGALPHCO_00895 3.9e-248 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IGALPHCO_00896 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
IGALPHCO_00898 1.86e-308 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IGALPHCO_00899 0.0 XK27_08315 - - M - - - Sulfatase
IGALPHCO_00900 1.2e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IGALPHCO_00901 6.49e-268 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IGALPHCO_00902 7.93e-217 yqhA - - G - - - Aldose 1-epimerase
IGALPHCO_00903 3.83e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
IGALPHCO_00904 6.21e-152 - - - - - - - -
IGALPHCO_00905 7.72e-228 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
IGALPHCO_00906 9.65e-95 - - - S - - - GtrA-like protein
IGALPHCO_00907 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGALPHCO_00908 1.45e-60 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
IGALPHCO_00909 9.1e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGALPHCO_00910 2.4e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
IGALPHCO_00911 1.05e-187 - - - - - - - -
IGALPHCO_00912 8.33e-182 - - - - - - - -
IGALPHCO_00913 1.44e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
IGALPHCO_00914 2.76e-262 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
IGALPHCO_00915 1.13e-184 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IGALPHCO_00916 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGALPHCO_00917 1.96e-45 - - - S - - - Protein of unknown function (DUF2922)
IGALPHCO_00918 3.41e-37 - - - - - - - -
IGALPHCO_00919 1.67e-175 - - - - - - - -
IGALPHCO_00920 8.74e-95 - - - - - - - -
IGALPHCO_00921 1.83e-25 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_00922 1.76e-74 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
IGALPHCO_00923 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
IGALPHCO_00924 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
IGALPHCO_00925 0.0 - - - S - - - Bacterial membrane protein, YfhO
IGALPHCO_00926 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
IGALPHCO_00928 1.41e-213 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IGALPHCO_00929 1.27e-172 rpl - - K - - - Helix-turn-helix domain, rpiR family
IGALPHCO_00930 3.79e-208 - - - D - - - transport
IGALPHCO_00931 3.3e-235 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
IGALPHCO_00932 1.08e-285 yqjV - - EGP - - - Major Facilitator Superfamily
IGALPHCO_00933 1.93e-286 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
IGALPHCO_00934 2.53e-133 yitW - - S - - - Iron-sulfur cluster assembly protein
IGALPHCO_00935 8.75e-177 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGALPHCO_00936 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
IGALPHCO_00938 3.01e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
IGALPHCO_00939 3.03e-50 - - - K - - - Helix-turn-helix XRE-family like proteins
IGALPHCO_00940 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
IGALPHCO_00941 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IGALPHCO_00942 0.0 - - - S - - - Calcineurin-like phosphoesterase
IGALPHCO_00943 1.13e-107 - - - - - - - -
IGALPHCO_00944 6.11e-189 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGALPHCO_00945 1.11e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGALPHCO_00946 1.28e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IGALPHCO_00947 1.16e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
IGALPHCO_00949 6.03e-114 usp5 - - T - - - universal stress protein
IGALPHCO_00950 1.45e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IGALPHCO_00951 3.53e-169 - - - K - - - UTRA domain
IGALPHCO_00952 1.76e-128 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGALPHCO_00953 3.15e-113 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
IGALPHCO_00954 4.76e-14 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
IGALPHCO_00955 1.27e-53 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IGALPHCO_00956 2.17e-134 - - - - - - - -
IGALPHCO_00957 3.2e-239 - - - S - - - zinc-ribbon domain
IGALPHCO_00958 7.23e-51 - - - - - - - -
IGALPHCO_00959 2.8e-238 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
IGALPHCO_00960 2.67e-98 - - - - - - - -
IGALPHCO_00961 4.76e-119 - - - - - - - -
IGALPHCO_00962 9.31e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
IGALPHCO_00963 4.19e-84 - - - S - - - Cupredoxin-like domain
IGALPHCO_00964 3.13e-65 - - - S - - - Cupredoxin-like domain
IGALPHCO_00965 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IGALPHCO_00966 0.0 - - - E - - - Amino acid permease
IGALPHCO_00967 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
IGALPHCO_00968 3.96e-314 ynbB - - P - - - aluminum resistance
IGALPHCO_00969 3.72e-86 - - - K - - - Acetyltransferase (GNAT) domain
IGALPHCO_00970 3.6e-302 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
IGALPHCO_00971 4.45e-90 - - - S - - - Iron-sulphur cluster biosynthesis
IGALPHCO_00972 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IGALPHCO_00973 1.48e-75 eriC - - P ko:K03281 - ko00000 chloride
IGALPHCO_00974 1.33e-276 - - - S - - - Sterol carrier protein domain
IGALPHCO_00975 2.71e-200 - - - I - - - Acyltransferase
IGALPHCO_00976 1.24e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
IGALPHCO_00977 1.45e-162 - - - S - - - Protein of unknown function (DUF975)
IGALPHCO_00978 3.05e-176 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IGALPHCO_00979 6.76e-52 - - - S - - - Plasmid replication protein
IGALPHCO_00981 6.35e-48 - - - M - - - Plasmid recombination enzyme
IGALPHCO_00982 1.75e-119 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
IGALPHCO_00983 6.89e-195 yitS - - S - - - EDD domain protein, DegV family
IGALPHCO_00984 1.07e-23 - - - - - - - -
IGALPHCO_00985 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
IGALPHCO_00986 1.17e-181 - - - K - - - Helix-turn-helix domain
IGALPHCO_00987 0.0 fusA1 - - J - - - elongation factor G
IGALPHCO_00988 3.68e-258 eriC - - P ko:K03281 - ko00000 chloride
IGALPHCO_00990 5.97e-241 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IGALPHCO_00991 1.21e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IGALPHCO_00992 2.64e-211 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGALPHCO_00993 9.29e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IGALPHCO_00994 3.15e-141 - - - KQ - - - helix_turn_helix, mercury resistance
IGALPHCO_00995 3.71e-280 - - - L - - - COG3547 Transposase and inactivated derivatives
IGALPHCO_00996 1.63e-155 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
IGALPHCO_00997 5.82e-275 - - - - - - - -
IGALPHCO_00998 4.44e-111 - - - S - - - Domain of unknown function (DUF4767)
IGALPHCO_00999 4.66e-148 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
IGALPHCO_01001 1.1e-108 - - - - - - - -
IGALPHCO_01002 2.69e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGALPHCO_01003 1.26e-132 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IGALPHCO_01004 3.55e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IGALPHCO_01005 2.09e-277 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IGALPHCO_01006 2.45e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IGALPHCO_01007 9.52e-205 - - - - - - - -
IGALPHCO_01008 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGALPHCO_01009 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IGALPHCO_01010 1.8e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IGALPHCO_01011 2.78e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IGALPHCO_01012 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IGALPHCO_01013 2.6e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
IGALPHCO_01014 1.19e-235 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IGALPHCO_01015 3.34e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGALPHCO_01016 1.74e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
IGALPHCO_01017 4e-66 ylbG - - S - - - UPF0298 protein
IGALPHCO_01018 1.36e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IGALPHCO_01019 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IGALPHCO_01020 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGALPHCO_01021 3.08e-47 ykzG - - S - - - Belongs to the UPF0356 family
IGALPHCO_01022 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGALPHCO_01023 6.85e-225 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IGALPHCO_01024 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IGALPHCO_01025 6.91e-149 - - - S - - - repeat protein
IGALPHCO_01026 2.24e-161 pgm - - G - - - Phosphoglycerate mutase family
IGALPHCO_01027 1.23e-275 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IGALPHCO_01028 1.27e-76 XK27_04120 - - S - - - Putative amino acid metabolism
IGALPHCO_01029 8.3e-274 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
IGALPHCO_01030 1.02e-164 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGALPHCO_01031 6.32e-52 - - - - - - - -
IGALPHCO_01032 1.81e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IGALPHCO_01033 3.93e-45 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IGALPHCO_01034 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IGALPHCO_01035 4.46e-162 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
IGALPHCO_01036 1.39e-187 ylmH - - S - - - S4 domain protein
IGALPHCO_01037 1.36e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
IGALPHCO_01038 9.26e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IGALPHCO_01039 6.35e-311 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGALPHCO_01040 5.2e-309 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IGALPHCO_01041 4.49e-197 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IGALPHCO_01042 5.53e-265 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGALPHCO_01043 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IGALPHCO_01044 1.28e-226 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGALPHCO_01045 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IGALPHCO_01046 3.95e-73 ftsL - - D - - - Cell division protein FtsL
IGALPHCO_01047 1.17e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IGALPHCO_01048 1.89e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IGALPHCO_01049 2.2e-68 - - - S - - - Protein of unknown function (DUF3397)
IGALPHCO_01050 2.36e-19 - - - S - - - Protein of unknown function (DUF4044)
IGALPHCO_01051 1.1e-120 mreD - - - ko:K03571 - ko00000,ko03036 -
IGALPHCO_01052 1.17e-188 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IGALPHCO_01053 3.11e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
IGALPHCO_01054 9.17e-144 radC - - L ko:K03630 - ko00000 DNA repair protein
IGALPHCO_01055 1.1e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
IGALPHCO_01056 1.92e-300 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IGALPHCO_01057 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IGALPHCO_01058 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
IGALPHCO_01059 1.21e-233 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
IGALPHCO_01060 5.19e-158 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IGALPHCO_01061 4.43e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGALPHCO_01062 1.75e-275 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
IGALPHCO_01063 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IGALPHCO_01065 7.54e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IGALPHCO_01066 1.06e-109 - - - S - - - Protein of unknown function (DUF1694)
IGALPHCO_01067 4.01e-298 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
IGALPHCO_01068 9.34e-08 - - - - - - - -
IGALPHCO_01069 3.52e-106 uspA - - T - - - universal stress protein
IGALPHCO_01070 1.3e-284 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IGALPHCO_01071 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
IGALPHCO_01072 5.54e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IGALPHCO_01073 3.34e-18 - - - S - - - DNA-directed RNA polymerase subunit beta
IGALPHCO_01074 3.53e-229 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
IGALPHCO_01075 3.07e-42 - - - S - - - Protein of unknown function (DUF1146)
IGALPHCO_01076 1.21e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IGALPHCO_01077 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IGALPHCO_01078 1.21e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IGALPHCO_01079 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IGALPHCO_01080 1.13e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGALPHCO_01081 5.6e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IGALPHCO_01082 1.75e-35 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGALPHCO_01083 7.4e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IGALPHCO_01084 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IGALPHCO_01085 8.5e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IGALPHCO_01086 1.52e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IGALPHCO_01087 4.43e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IGALPHCO_01088 8.2e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IGALPHCO_01089 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
IGALPHCO_01090 6.5e-246 ampC - - V - - - Beta-lactamase
IGALPHCO_01093 5.55e-90 - - - - - - - -
IGALPHCO_01094 0.0 - - - EGP - - - Major Facilitator
IGALPHCO_01095 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IGALPHCO_01096 9.16e-138 vanZ - - V - - - VanZ like family
IGALPHCO_01097 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGALPHCO_01098 0.0 yclK - - T - - - Histidine kinase
IGALPHCO_01099 1.89e-166 - - - K - - - Transcriptional regulatory protein, C terminal
IGALPHCO_01100 4.63e-88 - - - S - - - SdpI/YhfL protein family
IGALPHCO_01101 1.21e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IGALPHCO_01102 3.45e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
IGALPHCO_01103 8.27e-133 - - - M - - - Protein of unknown function (DUF3737)
IGALPHCO_01104 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
IGALPHCO_01106 3.36e-289 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGALPHCO_01107 3.44e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
IGALPHCO_01108 1.71e-111 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IGALPHCO_01110 3.97e-77 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
IGALPHCO_01111 3.76e-54 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
IGALPHCO_01112 3.47e-222 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
IGALPHCO_01113 5.45e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
IGALPHCO_01114 6.1e-171 yebC - - K - - - Transcriptional regulatory protein
IGALPHCO_01115 2.53e-123 - - - S - - - VanZ like family
IGALPHCO_01116 8.3e-274 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGALPHCO_01117 5.11e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IGALPHCO_01118 8.42e-148 - - - S - - - Alpha/beta hydrolase family
IGALPHCO_01119 1.11e-37 - - - - - - - -
IGALPHCO_01120 1.81e-274 - - - S - - - Putative adhesin
IGALPHCO_01121 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_01122 1.18e-78 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGALPHCO_01123 1.14e-83 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGALPHCO_01124 1.67e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IGALPHCO_01125 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGALPHCO_01126 4.07e-220 ybbR - - S - - - YbbR-like protein
IGALPHCO_01127 6.38e-197 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGALPHCO_01128 9.5e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_01129 2.65e-176 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_01130 1.45e-171 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_01131 1.46e-261 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IGALPHCO_01132 4.55e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
IGALPHCO_01133 6.4e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IGALPHCO_01134 7.13e-110 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
IGALPHCO_01135 1.82e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
IGALPHCO_01136 1.02e-172 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IGALPHCO_01137 1.69e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
IGALPHCO_01138 6.97e-121 - - - - - - - -
IGALPHCO_01139 4.65e-112 - - - - - - - -
IGALPHCO_01140 1.13e-137 - - - K ko:K06977 - ko00000 acetyltransferase
IGALPHCO_01141 2.95e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IGALPHCO_01142 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IGALPHCO_01143 7.52e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
IGALPHCO_01144 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGALPHCO_01145 5.9e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGALPHCO_01146 7.02e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IGALPHCO_01147 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IGALPHCO_01148 3.72e-238 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
IGALPHCO_01150 5.59e-164 ycaM - - E - - - amino acid
IGALPHCO_01151 1.12e-174 ycaM - - E - - - amino acid
IGALPHCO_01152 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IGALPHCO_01153 2.02e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IGALPHCO_01154 1.54e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IGALPHCO_01155 1.58e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IGALPHCO_01156 2.04e-117 - - - S - - - Short repeat of unknown function (DUF308)
IGALPHCO_01157 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGALPHCO_01158 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IGALPHCO_01159 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IGALPHCO_01160 1.66e-206 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
IGALPHCO_01161 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IGALPHCO_01162 2.96e-265 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IGALPHCO_01163 0.0 - - - - - - - -
IGALPHCO_01164 1.39e-279 - - - I - - - Protein of unknown function (DUF2974)
IGALPHCO_01165 1.27e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
IGALPHCO_01166 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IGALPHCO_01167 1.15e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
IGALPHCO_01168 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IGALPHCO_01169 1.42e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
IGALPHCO_01170 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IGALPHCO_01171 5.89e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGALPHCO_01172 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IGALPHCO_01173 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGALPHCO_01174 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGALPHCO_01175 7.88e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IGALPHCO_01176 5.33e-30 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IGALPHCO_01177 3.59e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IGALPHCO_01178 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGALPHCO_01179 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
IGALPHCO_01180 8.89e-80 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IGALPHCO_01181 4.86e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGALPHCO_01182 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IGALPHCO_01183 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IGALPHCO_01184 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IGALPHCO_01185 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGALPHCO_01186 3.23e-96 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
IGALPHCO_01187 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGALPHCO_01188 1.56e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
IGALPHCO_01189 5.58e-146 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IGALPHCO_01190 2.36e-116 - - - - - - - -
IGALPHCO_01191 6.65e-99 - - - - - - - -
IGALPHCO_01192 5.48e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
IGALPHCO_01193 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IGALPHCO_01194 2.17e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
IGALPHCO_01195 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
IGALPHCO_01196 1.02e-34 - - - - - - - -
IGALPHCO_01197 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
IGALPHCO_01198 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGALPHCO_01199 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IGALPHCO_01200 1.15e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IGALPHCO_01201 3.47e-211 coiA - - S ko:K06198 - ko00000 Competence protein
IGALPHCO_01202 5.4e-140 yjbH - - Q - - - Thioredoxin
IGALPHCO_01203 2.51e-143 - - - S - - - CYTH
IGALPHCO_01204 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
IGALPHCO_01205 3.58e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGALPHCO_01206 1.08e-217 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IGALPHCO_01207 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
IGALPHCO_01208 1.29e-301 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IGALPHCO_01209 6.1e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
IGALPHCO_01210 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
IGALPHCO_01211 5.14e-268 XK27_05220 - - S - - - AI-2E family transporter
IGALPHCO_01212 8e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IGALPHCO_01213 6.82e-99 - - - S - - - Protein of unknown function (DUF1149)
IGALPHCO_01214 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IGALPHCO_01215 2e-282 ymfF - - S - - - Peptidase M16 inactive domain protein
IGALPHCO_01216 2.87e-288 ymfH - - S - - - Peptidase M16
IGALPHCO_01217 9.65e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
IGALPHCO_01218 1.71e-177 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
IGALPHCO_01219 7.62e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGALPHCO_01220 2.99e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGALPHCO_01221 2.52e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IGALPHCO_01222 9.48e-262 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
IGALPHCO_01223 2.31e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
IGALPHCO_01224 4.57e-288 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
IGALPHCO_01225 7.79e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
IGALPHCO_01226 3.97e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGALPHCO_01227 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGALPHCO_01228 3.42e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGALPHCO_01229 6.45e-41 - - - - - - - -
IGALPHCO_01230 6.79e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IGALPHCO_01231 5.09e-201 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGALPHCO_01232 4.51e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IGALPHCO_01233 1.05e-221 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IGALPHCO_01234 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
IGALPHCO_01235 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
IGALPHCO_01236 3.03e-226 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IGALPHCO_01237 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
IGALPHCO_01238 4.7e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
IGALPHCO_01240 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IGALPHCO_01241 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IGALPHCO_01242 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGALPHCO_01243 5.26e-200 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
IGALPHCO_01244 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
IGALPHCO_01245 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
IGALPHCO_01246 1.32e-271 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
IGALPHCO_01247 9.44e-27 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGALPHCO_01248 8.11e-278 - - - M - - - LPXTG-motif cell wall anchor domain protein
IGALPHCO_01249 4.87e-236 - - - S - - - AAA domain
IGALPHCO_01250 7.96e-159 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGALPHCO_01251 2.39e-16 - - - - - - - -
IGALPHCO_01252 9.99e-53 - - - - - - - -
IGALPHCO_01253 3.4e-198 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
IGALPHCO_01254 3.56e-68 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
IGALPHCO_01255 3.17e-166 - - - G - - - Belongs to the phosphoglycerate mutase family
IGALPHCO_01256 1.04e-140 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IGALPHCO_01257 1.38e-194 - - - GM - - - NmrA-like family
IGALPHCO_01258 8.24e-129 - - - K - - - Transcriptional regulator C-terminal region
IGALPHCO_01259 3.99e-258 - - - S - - - membrane
IGALPHCO_01260 1.08e-112 - - - GM - - - NAD(P)H-binding
IGALPHCO_01261 1.24e-16 - - - GM - - - NAD(P)H-binding
IGALPHCO_01262 8.02e-161 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
IGALPHCO_01263 7.99e-149 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGALPHCO_01264 1.13e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IGALPHCO_01265 1.08e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IGALPHCO_01266 5.49e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IGALPHCO_01267 1.18e-179 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGALPHCO_01268 1.41e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGALPHCO_01269 6.38e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGALPHCO_01270 1.91e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IGALPHCO_01271 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGALPHCO_01272 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IGALPHCO_01273 1.92e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IGALPHCO_01274 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IGALPHCO_01275 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGALPHCO_01276 1.4e-154 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IGALPHCO_01277 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IGALPHCO_01278 5.78e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
IGALPHCO_01279 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IGALPHCO_01280 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IGALPHCO_01281 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IGALPHCO_01282 3.04e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IGALPHCO_01283 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IGALPHCO_01284 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGALPHCO_01285 6.1e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IGALPHCO_01286 1.18e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IGALPHCO_01287 6.02e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IGALPHCO_01288 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IGALPHCO_01289 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IGALPHCO_01290 3e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IGALPHCO_01291 3.69e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IGALPHCO_01292 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IGALPHCO_01293 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IGALPHCO_01294 1.99e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IGALPHCO_01295 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IGALPHCO_01296 1.02e-62 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IGALPHCO_01297 1.16e-212 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
IGALPHCO_01298 1.5e-20 - - - S - - - CsbD-like
IGALPHCO_01299 1.83e-54 - - - S - - - Transglycosylase associated protein
IGALPHCO_01300 6.22e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IGALPHCO_01301 0.0 - - - L - - - Helicase C-terminal domain protein
IGALPHCO_01302 5.31e-175 - - - S - - - Alpha beta hydrolase
IGALPHCO_01303 2.89e-09 - - - K ko:K15773 - ko00000,ko02048,ko03000 peptidyl-tyrosine sulfation
IGALPHCO_01304 3.48e-212 arbZ - - I - - - Phosphate acyltransferases
IGALPHCO_01305 2.24e-239 - - - M - - - Glycosyl transferase family 8
IGALPHCO_01306 1.46e-298 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IGALPHCO_01307 6.85e-132 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IGALPHCO_01308 2.53e-139 - - - S - - - SNARE associated Golgi protein
IGALPHCO_01309 1.11e-199 - - - I - - - alpha/beta hydrolase fold
IGALPHCO_01310 5.94e-160 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
IGALPHCO_01311 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IGALPHCO_01312 2.89e-227 - - - - - - - -
IGALPHCO_01313 1.29e-164 - - - S - - - SNARE associated Golgi protein
IGALPHCO_01314 3.98e-188 - - - S - - - haloacid dehalogenase-like hydrolase
IGALPHCO_01315 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
IGALPHCO_01316 7.62e-126 yobS - - K - - - Bacterial regulatory proteins, tetR family
IGALPHCO_01317 3.27e-206 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IGALPHCO_01318 1.86e-213 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
IGALPHCO_01319 8.58e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
IGALPHCO_01320 2.6e-113 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IGALPHCO_01321 2.41e-96 yybA - - K - - - Transcriptional regulator
IGALPHCO_01322 4.76e-75 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IGALPHCO_01323 9.33e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGALPHCO_01324 8.06e-315 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
IGALPHCO_01325 3.96e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGALPHCO_01326 3.57e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
IGALPHCO_01327 8.41e-260 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
IGALPHCO_01328 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IGALPHCO_01329 1.25e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
IGALPHCO_01330 1.36e-203 dkgB - - S - - - reductase
IGALPHCO_01331 3.02e-255 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
IGALPHCO_01332 2.82e-235 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
IGALPHCO_01333 4.35e-201 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IGALPHCO_01334 3.56e-145 yviA - - S - - - Protein of unknown function (DUF421)
IGALPHCO_01335 2.34e-97 - - - S - - - Protein of unknown function (DUF3290)
IGALPHCO_01336 6.59e-314 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IGALPHCO_01337 6.63e-127 - - - S - - - PAS domain
IGALPHCO_01338 1.4e-187 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
IGALPHCO_01339 0.0 - - - GM ko:K13732 ko05100,map05100 ko00000,ko00001 domain, Protein
IGALPHCO_01340 2.42e-69 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IGALPHCO_01341 9.28e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IGALPHCO_01342 9.55e-118 - - - - - - - -
IGALPHCO_01343 1.44e-186 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IGALPHCO_01344 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IGALPHCO_01345 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
IGALPHCO_01346 1.7e-182 - - - S - - - PAS domain
IGALPHCO_01347 7.59e-305 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGALPHCO_01348 1.27e-274 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
IGALPHCO_01349 1.97e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IGALPHCO_01350 8.61e-89 - - - - - - - -
IGALPHCO_01351 4.65e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
IGALPHCO_01352 5.58e-180 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
IGALPHCO_01353 2.18e-216 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IGALPHCO_01354 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_01355 3.36e-196 - - - EG - - - EamA-like transporter family
IGALPHCO_01356 1.72e-120 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
IGALPHCO_01357 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
IGALPHCO_01360 3.18e-106 yhaH - - S - - - Protein of unknown function (DUF805)
IGALPHCO_01361 5.8e-146 - - - S - - - Protein of unknown function (DUF969)
IGALPHCO_01362 1.37e-199 - - - S - - - Protein of unknown function (DUF979)
IGALPHCO_01363 2.07e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IGALPHCO_01364 2.33e-47 - - - - - - - -
IGALPHCO_01365 2.24e-204 mutR - - K - - - Helix-turn-helix XRE-family like proteins
IGALPHCO_01366 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
IGALPHCO_01367 1.81e-141 - - - S - - - Putative adhesin
IGALPHCO_01368 6.87e-258 napA - - P - - - Sodium/hydrogen exchanger family
IGALPHCO_01369 0.0 cadA - - P - - - P-type ATPase
IGALPHCO_01370 4.76e-111 ykuL - - S - - - (CBS) domain
IGALPHCO_01371 5.45e-61 - - - - - - - -
IGALPHCO_01372 1.88e-66 - - - - - - - -
IGALPHCO_01373 9.74e-78 - - - - - - - -
IGALPHCO_01375 2.11e-271 - - - S - - - Membrane
IGALPHCO_01376 6.13e-52 - - - - - - - -
IGALPHCO_01377 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
IGALPHCO_01378 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGALPHCO_01379 4.7e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
IGALPHCO_01380 5.16e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGALPHCO_01381 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IGALPHCO_01382 1.05e-181 pbpX2 - - V - - - Beta-lactamase
IGALPHCO_01383 1.97e-275 - - - E - - - Major Facilitator Superfamily
IGALPHCO_01384 2.11e-53 - - - - - - - -
IGALPHCO_01385 6.12e-313 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGALPHCO_01386 1.69e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IGALPHCO_01387 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
IGALPHCO_01388 0.0 - - - E ko:K03294 - ko00000 Amino Acid
IGALPHCO_01389 8.54e-144 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
IGALPHCO_01390 1.06e-297 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IGALPHCO_01392 1.15e-25 - - - - - - - -
IGALPHCO_01393 1.4e-44 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IGALPHCO_01394 1.1e-128 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
IGALPHCO_01395 1.34e-117 - - - K - - - Arabinose-binding domain of AraC transcription regulator, N-term
IGALPHCO_01397 8.45e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
IGALPHCO_01398 1.79e-100 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
IGALPHCO_01399 1.73e-103 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IGALPHCO_01400 8.41e-235 - - - M - - - Glycosyl transferase family 8
IGALPHCO_01401 8.6e-86 - - - S - - - Domain of unknown function (DUF956)
IGALPHCO_01402 4.25e-220 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
IGALPHCO_01403 1.23e-166 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
IGALPHCO_01404 8.1e-236 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IGALPHCO_01405 3.02e-44 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
IGALPHCO_01406 6.42e-90 - - - M - - - Rib/alpha-like repeat
IGALPHCO_01407 7.23e-60 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IGALPHCO_01408 4.15e-145 - - - K - - - helix_turn_helix, mercury resistance
IGALPHCO_01409 9.07e-291 sptS - - T - - - Histidine kinase
IGALPHCO_01410 1.01e-149 dltr - - K - - - response regulator
IGALPHCO_01411 1.93e-145 - - - T - - - Region found in RelA / SpoT proteins
IGALPHCO_01412 7.25e-88 - - - O - - - OsmC-like protein
IGALPHCO_01413 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IGALPHCO_01414 1.33e-226 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_01415 8.55e-216 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IGALPHCO_01416 1.64e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IGALPHCO_01417 2.97e-207 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
IGALPHCO_01418 1.36e-100 ykuP - - C ko:K03839 - ko00000 Flavodoxin
IGALPHCO_01419 3.74e-115 gtcA1 - - S - - - Teichoic acid glycosylation protein
IGALPHCO_01420 3.66e-275 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IGALPHCO_01423 1.88e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGALPHCO_01424 5.69e-280 yfmL - - L - - - DEAD DEAH box helicase
IGALPHCO_01425 1.34e-175 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IGALPHCO_01426 6.91e-297 - - - E ko:K03294 - ko00000 amino acid
IGALPHCO_01427 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
IGALPHCO_01428 4.03e-301 yhdP - - S - - - Transporter associated domain
IGALPHCO_01429 6.35e-160 - - - - - - - -
IGALPHCO_01430 3.14e-147 - - - C - - - nitroreductase
IGALPHCO_01431 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
IGALPHCO_01432 8.19e-86 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IGALPHCO_01433 1.39e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
IGALPHCO_01434 3.96e-224 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
IGALPHCO_01435 1.62e-165 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGALPHCO_01436 4.05e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGALPHCO_01437 1.98e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IGALPHCO_01438 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
IGALPHCO_01439 2.22e-219 - - - L - - - Psort location Cytoplasmic, score
IGALPHCO_01441 2.89e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
IGALPHCO_01442 6.89e-181 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGALPHCO_01443 4.49e-189 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGALPHCO_01444 1.19e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
IGALPHCO_01445 4.88e-216 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IGALPHCO_01446 9.53e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IGALPHCO_01447 1.13e-124 - - - K - - - Acetyltransferase (GNAT) domain
IGALPHCO_01448 3.39e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_01449 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
IGALPHCO_01450 6.46e-206 - - - S - - - Phospholipase, patatin family
IGALPHCO_01451 7.06e-270 pacL - - P - - - Cation transporter/ATPase, N-terminus
IGALPHCO_01452 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
IGALPHCO_01454 6.77e-71 - - - S - - - Enterocin A Immunity
IGALPHCO_01458 8.53e-287 - - - S - - - CAAX protease self-immunity
IGALPHCO_01459 1.09e-61 - - - S - - - Enterocin A Immunity
IGALPHCO_01461 1.2e-127 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
IGALPHCO_01462 6.15e-40 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IGALPHCO_01463 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
IGALPHCO_01464 1.34e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
IGALPHCO_01465 0.0 - - - S - - - Putative threonine/serine exporter
IGALPHCO_01466 1.04e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IGALPHCO_01467 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IGALPHCO_01468 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IGALPHCO_01469 5.8e-116 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_01470 1.29e-31 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGALPHCO_01471 2.32e-200 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IGALPHCO_01472 2.33e-87 - - - L - - - nuclease
IGALPHCO_01473 7.26e-183 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
IGALPHCO_01474 2e-64 - - - K - - - Helix-turn-helix domain
IGALPHCO_01475 1.78e-241 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IGALPHCO_01476 2.8e-238 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
IGALPHCO_01477 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
IGALPHCO_01478 2.7e-38 - - - S - - - Sugar efflux transporter for intercellular exchange
IGALPHCO_01479 2.48e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGALPHCO_01480 1.03e-131 - - - I - - - PAP2 superfamily
IGALPHCO_01482 6.94e-201 lysR5 - - K - - - LysR substrate binding domain
IGALPHCO_01483 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
IGALPHCO_01484 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
IGALPHCO_01485 8.21e-127 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IGALPHCO_01486 3.46e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IGALPHCO_01487 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGALPHCO_01488 0.0 potE - - E - - - Amino Acid
IGALPHCO_01489 5.93e-124 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGALPHCO_01490 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IGALPHCO_01491 1.33e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
IGALPHCO_01492 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IGALPHCO_01493 2.01e-251 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IGALPHCO_01494 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IGALPHCO_01495 4.19e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGALPHCO_01496 1.54e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IGALPHCO_01497 4.37e-124 - - - S - - - GyrI-like small molecule binding domain
IGALPHCO_01498 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
IGALPHCO_01499 4.29e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IGALPHCO_01500 3.48e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IGALPHCO_01501 2.75e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IGALPHCO_01502 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IGALPHCO_01503 1.09e-62 - - - J - - - ribosomal protein
IGALPHCO_01504 1.08e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
IGALPHCO_01505 4.31e-278 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IGALPHCO_01506 2.3e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IGALPHCO_01507 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGALPHCO_01508 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IGALPHCO_01509 2.69e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IGALPHCO_01510 3.37e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IGALPHCO_01511 5.91e-176 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGALPHCO_01512 2.02e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IGALPHCO_01513 1.01e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IGALPHCO_01514 8.74e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IGALPHCO_01515 7.4e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IGALPHCO_01516 4.42e-249 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
IGALPHCO_01517 2.35e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
IGALPHCO_01518 6.29e-294 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
IGALPHCO_01519 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_01520 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_01521 4.85e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
IGALPHCO_01522 1.7e-45 ynzC - - S - - - UPF0291 protein
IGALPHCO_01523 7.82e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGALPHCO_01524 2.15e-151 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
IGALPHCO_01525 2.61e-96 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
IGALPHCO_01526 1.15e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGALPHCO_01527 2.61e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IGALPHCO_01528 3.7e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IGALPHCO_01529 2.07e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IGALPHCO_01530 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IGALPHCO_01531 1.99e-291 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGALPHCO_01532 3.48e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IGALPHCO_01533 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IGALPHCO_01534 5.21e-269 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IGALPHCO_01535 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IGALPHCO_01536 2.75e-79 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IGALPHCO_01537 6.66e-309 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_01538 6.3e-199 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGALPHCO_01539 4.31e-230 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_01540 8.34e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGALPHCO_01541 1.72e-244 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGALPHCO_01542 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGALPHCO_01543 1.23e-231 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IGALPHCO_01544 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGALPHCO_01545 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
IGALPHCO_01546 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
IGALPHCO_01547 6.36e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IGALPHCO_01548 1.76e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IGALPHCO_01549 3.18e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IGALPHCO_01550 6.45e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IGALPHCO_01551 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IGALPHCO_01552 1.29e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IGALPHCO_01553 1.81e-309 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGALPHCO_01554 9.69e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IGALPHCO_01555 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGALPHCO_01556 3.3e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IGALPHCO_01557 3.6e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IGALPHCO_01558 7.04e-63 - - - - - - - -
IGALPHCO_01559 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IGALPHCO_01560 4.35e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
IGALPHCO_01561 5.32e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IGALPHCO_01562 2.74e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGALPHCO_01563 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGALPHCO_01564 4.13e-193 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IGALPHCO_01565 1e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGALPHCO_01566 7.32e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
IGALPHCO_01567 1.73e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGALPHCO_01568 1.57e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
IGALPHCO_01569 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IGALPHCO_01570 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IGALPHCO_01571 1.9e-79 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IGALPHCO_01572 2.81e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGALPHCO_01573 8.02e-271 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
IGALPHCO_01574 1.17e-17 - - - - - - - -
IGALPHCO_01575 2.18e-83 - - - - - - - -
IGALPHCO_01576 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
IGALPHCO_01577 2.02e-120 - - - S - - - ECF-type riboflavin transporter, S component
IGALPHCO_01578 7.71e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
IGALPHCO_01579 1.44e-72 - - - - - - - -
IGALPHCO_01580 6.43e-160 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IGALPHCO_01581 0.0 - - - S - - - Predicted membrane protein (DUF2207)
IGALPHCO_01582 7.4e-225 - - - I - - - Carboxylesterase family
IGALPHCO_01583 3e-75 - - - K - - - helix_turn_helix, arabinose operon control protein
IGALPHCO_01585 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IGALPHCO_01586 2.88e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
IGALPHCO_01587 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGALPHCO_01588 3.24e-102 - - - K - - - MerR HTH family regulatory protein
IGALPHCO_01589 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
IGALPHCO_01590 2.18e-120 - - - S - - - Domain of unknown function (DUF4811)
IGALPHCO_01591 1.98e-190 - - - M - - - Glycosyl transferase family 2
IGALPHCO_01592 8.04e-139 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
IGALPHCO_01593 4.86e-92 - - - - - - - -
IGALPHCO_01594 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IGALPHCO_01596 3.69e-183 - - - S - - - haloacid dehalogenase-like hydrolase
IGALPHCO_01597 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
IGALPHCO_01598 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IGALPHCO_01599 1.22e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
IGALPHCO_01600 8.75e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IGALPHCO_01601 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IGALPHCO_01602 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IGALPHCO_01603 8.05e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IGALPHCO_01604 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IGALPHCO_01605 8.18e-141 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
IGALPHCO_01606 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGALPHCO_01607 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGALPHCO_01608 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IGALPHCO_01610 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IGALPHCO_01611 9.21e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGALPHCO_01612 1.92e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IGALPHCO_01613 0.0 - - - S - - - membrane
IGALPHCO_01614 0.0 - - - S - - - membrane
IGALPHCO_01615 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGALPHCO_01616 2.07e-312 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IGALPHCO_01617 2.22e-78 - - - J ko:K07571 - ko00000 S1 RNA binding domain
IGALPHCO_01618 1.52e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IGALPHCO_01619 3.62e-46 yabO - - J - - - S4 domain protein
IGALPHCO_01620 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGALPHCO_01621 4.45e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IGALPHCO_01622 1.14e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IGALPHCO_01623 2.13e-158 - - - S - - - (CBS) domain
IGALPHCO_01624 4.08e-270 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGALPHCO_01625 1.75e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IGALPHCO_01626 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IGALPHCO_01627 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IGALPHCO_01628 8.98e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IGALPHCO_01629 0.0 - - - E - - - amino acid
IGALPHCO_01630 4.25e-172 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGALPHCO_01631 6.08e-183 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IGALPHCO_01632 1.62e-230 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
IGALPHCO_01633 3.01e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IGALPHCO_01634 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IGALPHCO_01635 1.15e-184 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
IGALPHCO_01636 1.78e-103 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
IGALPHCO_01637 1.46e-42 ydeP - - K - - - Transcriptional regulator, HxlR family
IGALPHCO_01638 1.25e-97 - - - - - - - -
IGALPHCO_01639 7.02e-105 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IGALPHCO_01640 1.85e-53 - - - - - - - -
IGALPHCO_01641 1.75e-259 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IGALPHCO_01642 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IGALPHCO_01643 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IGALPHCO_01644 1.78e-123 - - - - - - - -
IGALPHCO_01645 6.72e-10 - - - G - - - gluconokinase activity
IGALPHCO_01646 5.37e-107 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGALPHCO_01647 6.23e-102 ywnA - - K - - - Transcriptional regulator
IGALPHCO_01648 2.47e-226 - - - C - - - nadph quinone reductase
IGALPHCO_01649 3.19e-106 - - - K - - - Acetyltransferase (GNAT) domain
IGALPHCO_01650 3.27e-83 - - - S - - - Protein of unknown function (DUF3021)
IGALPHCO_01651 9.54e-97 - - - K - - - LytTr DNA-binding domain
IGALPHCO_01652 8.55e-189 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IGALPHCO_01653 5.66e-195 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGALPHCO_01654 1.14e-259 - - - S - - - Membrane
IGALPHCO_01655 2.37e-35 - - - P ko:K10716 - ko00000,ko02000 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IGALPHCO_01656 7.67e-10 - - - - - - - -
IGALPHCO_01657 6.18e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IGALPHCO_01658 5.34e-245 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IGALPHCO_01659 2.02e-78 ydeP - - K - - - Transcriptional regulator, HxlR family
IGALPHCO_01660 8.76e-85 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IGALPHCO_01661 0.0 - - - EGP - - - Major Facilitator
IGALPHCO_01662 5.31e-107 - - - K - - - Bacterial regulatory proteins, tetR family
IGALPHCO_01663 2.21e-276 - - - L - - - COG3547 Transposase and inactivated derivatives
IGALPHCO_01664 6.87e-69 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
IGALPHCO_01665 5.32e-35 - - - - - - - -
IGALPHCO_01666 8.9e-218 - - - K - - - Helix-turn-helix
IGALPHCO_01667 6.23e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
IGALPHCO_01668 1.91e-144 - - - K - - - transcriptional regulator
IGALPHCO_01670 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IGALPHCO_01671 6.92e-164 - - - K - - - Psort location CytoplasmicMembrane, score
IGALPHCO_01672 3.36e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IGALPHCO_01673 1.6e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
IGALPHCO_01674 5.13e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGALPHCO_01675 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IGALPHCO_01676 1.46e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IGALPHCO_01677 9.65e-95 - - - S - - - Domain of unknown function (DUF1934)
IGALPHCO_01678 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IGALPHCO_01679 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
IGALPHCO_01680 3.99e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IGALPHCO_01681 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGALPHCO_01682 7.34e-290 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGALPHCO_01683 1.36e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGALPHCO_01684 4.64e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
IGALPHCO_01685 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
IGALPHCO_01686 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IGALPHCO_01687 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
IGALPHCO_01688 2.38e-224 yvdE - - K - - - helix_turn _helix lactose operon repressor
IGALPHCO_01689 2.27e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGALPHCO_01690 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IGALPHCO_01691 1.91e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IGALPHCO_01692 1.22e-48 veg - - S - - - Biofilm formation stimulator VEG
IGALPHCO_01693 1.35e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IGALPHCO_01694 3.78e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IGALPHCO_01695 7.48e-188 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
IGALPHCO_01696 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGALPHCO_01697 4.11e-232 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
IGALPHCO_01698 1.03e-127 - - - S ko:K06872 - ko00000 TPM domain
IGALPHCO_01699 9.68e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
IGALPHCO_01700 2.46e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IGALPHCO_01701 1.03e-149 - - - E - - - Belongs to the SOS response-associated peptidase family
IGALPHCO_01703 8.03e-151 - - - - - - - -
IGALPHCO_01704 1.08e-122 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IGALPHCO_01705 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGALPHCO_01706 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGALPHCO_01707 3.44e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IGALPHCO_01708 7.13e-56 - - - - - - - -
IGALPHCO_01709 3.56e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
IGALPHCO_01710 2.81e-175 - - - K ko:K03492 - ko00000,ko03000 UTRA
IGALPHCO_01711 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGALPHCO_01712 6.47e-95 - - - S - - - Domain of unknown function (DUF3284)
IGALPHCO_01713 3.42e-167 - - - K ko:K03489 - ko00000,ko03000 UTRA
IGALPHCO_01714 6.29e-307 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGALPHCO_01715 3.84e-101 - - - - - - - -
IGALPHCO_01716 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGALPHCO_01717 4.47e-232 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGALPHCO_01718 2.9e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
IGALPHCO_01719 2.71e-281 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
IGALPHCO_01731 2.48e-80 - - - - - - - -
IGALPHCO_01738 7.37e-40 - - - - - - - -
IGALPHCO_01740 7.94e-36 - - - L ko:K07483 - ko00000 transposase activity
IGALPHCO_01741 3.55e-21 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
IGALPHCO_01742 5.9e-67 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
IGALPHCO_01743 0.0 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)